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<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP1</accession>
    <name>V6DSP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6676" checksum="8AAD764053E48135" modified="2014-02-19" version="1">MEASGDTTDRVTAFDRQDELRCRVIENLVHLVVTNNLVTIKILTRLAMKPRSLHLSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP4</accession>
    <name>V6DSP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C464_17232</name>
        <name evidence="5" type="ORF">BN903_197</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BAT" evidence="4">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="158"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="225" mass="24514" checksum="DD0F144A2F95F506" modified="2014-02-19" version="1">MTRIEYEVSDPSFVLTQLATAADCTLTYDGGVQQTATENYVFVTVDDAPLDTVVDATDGLTVVEDVQRIRGGDSGGVLRLQLSDPFLATELADHGAVLRSATATTAGTTLVVDLPASIEVRHVTQFLADRFGDLELVSKQTREQASEHGFYASVLDRLTDRQLEVLETAYYSGFFESPRKANGEAVANSLDISPQAFYQHIRTSQRKLFAALVDDHTPIATQHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP9</accession>
    <name>V6DSP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3813" checksum="C748D9232CBEDE1B" modified="2014-02-19" version="1">MLSVVCGTVSRHCLFAVSSKRVFTAVGILGITSALMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR0</accession>
    <name>V6DSR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exonuclease VII small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C444_07820</name>
        <name evidence="1" type="ORF">BN903_179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5819" checksum="ECE2A775F1872A07" modified="2014-02-19" version="1">MDRVEEIIEQLDTDEVSLDDGHDLYNEGQELLSEIRERLQEGDGEITEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR1</accession>
    <name>V6DSR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_09316</name>
        <name evidence="3" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="60"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11897" checksum="E2669354FCB7AB42" modified="2014-02-19" version="1">MLTEVDILEVARVVEGEASTGDSIAEEDSEWSWEGIKATGARYLPTRNVEIPAEAVRHFMTDDLVTVNATRTAKEVAQELISNDIEQVPLVSGTDLDGIVRDVDLLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR3</accession>
    <name>V6DSR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-isopropylmalate dehydratase small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuD</name>
        <name evidence="1" type="ORF">BN903_200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4286" checksum="63FC64264D4630B0" modified="2014-02-19" version="1">MSDPDERYDGDLLPEFLQSLVARGRLKPYMRASLDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR5</accession>
    <name>V6DSR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_06800</name>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076968.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119985at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="8918" checksum="45E367C24B436D11" modified="2014-02-19" version="1">MTDIEAAIREAFEHTEYDLGDVAVNRRQVRVPVIEEGADPDALRAVIEEALGADALAAVTVTTERIAGEDTVGTVVSFRYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR6</accession>
    <name>V6DSR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C437_15084</name>
        <name evidence="1" type="ORF">BN903_184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="11277" checksum="8CCA92DEBF7B7BBE" modified="2014-02-19" version="1">MNLYALQRFNTALRLQTESLGNRHYDAELNLYHVNSEVCKQMSKVILNLIYNLIMGREGGQTIAEPMSEAIEQSSSTDVYSIQTLEHLITMSLQVEKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR8</accession>
    <name>V6DSR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Hlac_2238</name>
        <name evidence="5" type="ORF">BN903_265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076364.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82473at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="67"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="251" mass="27522" checksum="DB83ADBC6D10DD7C" modified="2014-02-19" version="1">MDAKHPVRTTEKTLALVEELMDREPCGVTELADGLEMGKSAVHNHLTTLRKHGYVLKSGDEYQLGLKFLEVGGSTRKSMEFYQVAEPEVKSLADETGELANLLVEEQGMGVYLMRSKGEDAVDLDTYAGLRTHLHTTALGKAILAYLPESRVEEIIEQHGIEQKTSRSVGSREELFDALEGVRDRGYAIDDGERLEGLRCIAAPVKDSSDEVLGAISVSAPASRVSDDDLHGRLPERVLSAANVVELNINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSR9</accession>
    <name>V6DSR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09763</name>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="404" mass="42696" checksum="DBF085BA4AF621DA" modified="2014-02-19" version="1">MGAVADSPALAGSDAVAGSSSPVTEQTSTPQVDRANLTFRTLSTPAGAETRVSAYARGPDLGSSLGFATADTDAAVETAAVVRRIEGAESTVERQQHILAEINRIERAEVALESRQANAFAAHAAGEVSDRELVDELVRVAAIAREYDERLDEIDALAEATDGFSSPSRLDELQVALQVYEGPVREQALATARGQSPPTDMYVASSQGTVVLATVVDGEYVREVFRTDRWDRGGGPISNDLAIEVTEAAYPETTALREPDAFGAGAVQRITIPHEFGTLRTFVSGGTERVFVEHQRIELAAFPDSESVSESGDGFNVTVERTYPGGPVTVTVLDDETGEPVPNVTVTKSIGDGDSQAIGTTNAAGVVRTLSPSETYRITVVDEPRVVVVGDIDPLPTPRPIGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSS2</accession>
    <name>V6DSS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5301" checksum="5491396A23A09C2C" modified="2014-02-19" version="1">MSISDLYTDLLSYHLPTGASAEFVSLNHLLGISCSNSLAPAGHLYFNSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSS3</accession>
    <name>V6DSS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase (TCE33)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C471_10185</name>
        <name evidence="3" type="ORF">BN903_194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="174" mass="20486" checksum="71C36EAB5559005A" modified="2014-02-19" version="1">MDREFDSQQILEAIADRGVTYVVPKRMHTSEKAQAKRLLQRDQDHYVTDRKLHLGNNEWHETTLQYRRKKNSDRTDYGQYAVFMTNGDPSAITEYGKRWDIERGYKSIKRFMAATTSKDFVLRFFYFAFACLLYSIWRGIDMLFQCEKGGVYDREPVVTAQNTLTLLRQETGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSS4</accession>
    <name>V6DSS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04201</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8156" checksum="A0DD0CCAEFDFAB71" modified="2014-02-19" version="1">MFVLRPAAHEFVAVYVVFDRDGVLAQTVRDTYDLGPGLAAGLDASYPTDGDDSVGDDSDGGDEADGDDGGDFDALDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSS6</accession>
    <name>V6DSS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycyl-tRNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C470_06934</name>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7576" checksum="62C828CB3D3F4824" modified="2014-02-19" version="1">MYAIRSYYVSPAXVGRTAPVRXXXXXXXVLALPRLPSADELDRAARTGEPFASVADRYDAVDTDVETAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSS7</accession>
    <name>V6DSS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9775" checksum="F83B462564D2D75E" modified="2014-02-19" version="1">MFGPLQRIRNGFLGWVSNGDVVGDTGLDRLTCDGFASVRCPHYQRKYRRCVANLVDEIDTGSFGETVVGNDTVDSGLLECLLRGCSCRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSS8</accession>
    <name>V6DSS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C496_16052</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629628.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124641at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9697" checksum="E8299C3DF4CFC53F" modified="2014-02-19" version="1">MSEPQITLYRLQACPFCERVVRTLNELDLEYRSRYVEPMHSERNVVKRVSGARSVPAIVDRETGVTMSESANIVEYLNGTYGEGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST0</accession>
    <name>V6DST0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6073" checksum="EE6D19B08DAB5AD9" modified="2014-02-19" version="1">MPQNKLGYLFILILLLYARKCRGLRGRAPENGRRPVHRTAAVDASGTCGGECCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST2</accession>
    <name>V6DST2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Circadian clock protein, KaiC</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C468_01255</name>
        <name evidence="3" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010624">
        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KaiC" evidence="2">
        <location>
            <begin position="19"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="29223" checksum="F72B7000E5750343" modified="2014-02-19" version="1">MTVWPTLVPGEQQREVEPGTLSSGVAGLDELLHGGLDQGTVTIFSGPTGVGKTTTGLQFLSQAALEGKQSVLFQFEEAERTMRKRADAISLPLQAALDSGNMSIVEIAPEEYTVGQFEHLVREAVEDGTEVVMIDGSQGFQENLRGLDNTTGALLRIGRFLRAAGVSTILINEVHNITGNFHATEERTSNLADNIVFLRHVEYRGEMRKVIGTLKMRTSDFERGLRELEITADGIRVGEPLPQLRGILTGTPEWDDNDGGEETGSSEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST3</accession>
    <name>V6DST3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HSB1_40880</name>
        <name evidence="2" type="ORF">BN903_269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="17792" checksum="724C9C85E0408B04" modified="2014-02-19" version="1">MVRLPNLLRLLLLGIGALLARLGLVGRERAEETTDLAWPRIVTGLARMSKSVADTAMVGVALGQTAIAGMGFAGPFWGVSFAVGGGTAAGTIALVSQHFGADDRDELGQVVRSSVVLATAIALPVAALFWLTPRSLVGVLSDDPAAVAYGADYLRVLAVGVPFAVLNTYNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST4</accession>
    <name>V6DST4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein alpha/beta-subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_04226</name>
        <name evidence="3" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="189" mass="20108" checksum="01397028E74EB0ED" modified="2014-02-19" version="1">MKVLVTVKEVAEADDDFAIEGTDIAESDLEYDLNEWDDYAVEAAVQLAESGIADEVVAVTVGPERAEETIRMALAKGADRAVRVWDDALEGSFPDVASKVDLFEAVVAEEKPDLILGGVQAADTGFGATGVALAERIGFEHAAVVNHLGRRRGRGRRARPPRAGGGVEELTDVDLPAVLTVQTGLNEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST6</accession>
    <name>V6DST6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
            <ecNumber evidence="2">1.5.99.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_05573</name>
        <name evidence="2" type="ORF">BN903_209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.99.11" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="216" mass="23909" checksum="0939AE01705482A9" modified="2014-02-19" version="1">MDEYIELIRRYLRGDPEGFDGEFFSPSRTAFWEAFEPERASIPIYNGALGPANVRLTGQFADGWVPNLYPDSQFKEARGWLADGATRADRDPESIDVAMYVLTAVDEDPERARQAAAEHVAYYLRDIPGYYDRAAEQAGYEDVVEAVRSAPSMEAGADAVADGLLDHLAVVGTPDEARAQLDHLRELGVDLPIVRAPAGSDREWAERTLETFAPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST7</accession>
    <name>V6DST7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076981.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20673" checksum="FF0362A5E5DB94A2" modified="2014-02-19" version="1">MSEAGSTQAGAAYCRNCEQQVQPVGGVNRELGIILLFFGFIPGLVYLGGGWIMDQYGLLSKNCPICGDDNWSRQPVNNAGDSDRTVNGDDSEGELVAQHNASGSERARSGVAAKIQKWVIRTIKSWATVAIIVFPLFFFFSLSNVSMLVSTILSVSWFGVCIYGLHRRDLLHFGIHSPFYYREQKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DST8</accession>
    <name>V6DST8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6673" checksum="E8806DF6E7113E71" modified="2014-02-19" version="1">MSPRARRARAESLTDWSVQRVKFGLYCWFSTQNAAYISGKRRFGGDAPSTFMSVCGFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU0</accession>
    <name>V6DSU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dolichol kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04635</name>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076963.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96884at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="PTHR31303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="21543" checksum="3447746ACC95266A" modified="2014-02-19" version="1">MPLPAAAWRERVEFERRLVHASGTLYPVPYLLGWISWEATGRLMVLSVAVATLLEALRLTDSVGPLDPLYDALVREYEADGVAGYALYQVGMAATALLFAPVFAVPAMWMLSIGDPISGGLGENAATEPKRLSVVAAMVFVCFGIAVPYAIPEFGPDPGVIVALAGAIPAAVADGLPPLIRGVAVDDNLTIPPAAASGMFLAAALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU1</accession>
    <name>V6DSU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_04086</name>
        <name evidence="3" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="18"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="183" mass="19981" checksum="FDE0B70B312D8ABF" modified="2014-02-19" version="1">MPRENYQERLDDLRDGVVEMGETVCDRLDDAVAAAVSGDDDLARSVIEGDHEVNETYLALEDECTELLALQQPVAGDLRLVAASFKIITDLERVADLATNLADYGGPEGGVHPAVDVRRLXXXXXXXTPTATRTTARPTTRRSKPRSTRCHRRCSPCATSNGSPTTRSTSRRGPCTWSKTTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU2</accession>
    <name>V6DSU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C461_01477</name>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076976.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110906at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="10025" checksum="EE3C7D381823540F" modified="2014-02-19" version="1">MQHLIIRGDPDIRRDAVIEYDGEELVCFGINVQGGWHGPDEPQLWCTVGTEDEREAYDKREYVPHWLDVDAVDAEEIEVLSEKGALSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU4</accession>
    <name>V6DSU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_04672</name>
        <name evidence="1" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="349" mass="38058" checksum="BEE8DFB151AD8C80" modified="2014-02-19" version="1">MEMLPFVAGELSIVRSPETVTPADEDAGGGVGFLRASADDAPAASVPPGPXXXXXXXDTVEHAWVGDGVPLDANKATLDAYHRRLEAGQVEQSRISVLVVCNDEQMREEGDVADLYGLRDMVQFDIEVRHDLDRGEMREALASDVDFLHYIGHVDDRGMQCADSYLDLTDEDLEIGVSAFLLNACQSYRQGEALVHRGSRGGIVTLSDVANSPATKLGRIIARLMNSGFNLRTALHVAKRELITGHQYIVVGDGATTICQSRSGGAVVINAKRQNKQVNISTNIYPNGPYGVGTLSTLNLETVSSNYYVPAEIEAFNVAKNDFQNFLELETLPIFMNERLSWTDTISFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU5</accession>
    <name>V6DSU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4000" checksum="69D52B1051B1CC32" modified="2014-02-19" version="1">MSGCGRAGIPVSGRDEYVGTAVGSGESDTGVNAIELPFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU7</accession>
    <name>V6DSU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7022" checksum="2C5D07603D4BA59D" modified="2014-02-19" version="1">MSVGAGALPVVTGTALNRCFDVAIGDRVVRFVSRPKQCGNLPNTFRSSLSVNSIILAQRTLFNIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSU8</accession>
    <name>V6DSU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="148" mass="15716" checksum="410222393AD14C3B" modified="2014-02-19" version="1">MVELLAVVDGVDRVDALAVQVRRERVDVAADHGHVEVAPALVRERSPGGDRLVRDVPQVSATVFGDDEHAHHAPTPFSRRTSARRPADSPASPSMISASDSLSGSYISVIVSALSTSAAVRPRSARSFAAISLRCACRIPRRLATAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT11</accession>
    <name>V6DT11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_13145</name>
        <name evidence="1" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8503" checksum="D597944729E74DD8" modified="2014-02-19" version="1">MAADCTVIAADHPDAAADEVIADAGFCVEPTVDAITEILAAALDGTRPPTAPVDRAQQYDWDAIAEQAERTYRAAINDTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT12</accession>
    <name>V6DT12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4276" checksum="D27B1BD174433B3A" modified="2014-02-19" version="1">MHWSVWCPVPASGLDGTERPRLTSDRRLRRSAGGAILIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT14</accession>
    <name>V6DT14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C436_08514</name>
        <name evidence="1" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077018.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122029at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6705" checksum="0B11C9D36E446FA3" modified="2014-02-19" version="1">MRIITHTCPACGTIVAANELEGNRVMKCPGLGCQEVLEFDDLPQDARDHFLDNRERYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT19</accession>
    <name>V6DT19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5654" checksum="11340374668B8163" modified="2014-02-19" version="1">MLVIPGIIYIYPYAAGAFGFTFFATYLALPLVPALLLGLVAVWSMTAATADGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT30</accession>
    <name>V6DT30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4692" checksum="52E9852B97982BBF" modified="2014-02-19" version="1">MRSNWKDSRSRYLIVLFYGMISSLSRIYILCFNIRPYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT32</accession>
    <name>V6DT32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C449_09159</name>
        <name evidence="2" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="420" mass="49097" checksum="7574C8B2D5F36D6E" modified="2014-02-19" version="1">MKNIVLLTFDSLRADHCSHHGYDRDTTPNLADIAQNGISFSNAVSPASRTNPSMSGIFTGEHIINRDKISNPEHSKYHLNRHGTFVEELSEKGYSTAAFCPNAYSSRYYGFDNGFDKFEDFMFSSEKYKKLFDRHITESSVYTAVRNLRNLIRKEEAFRLWETYIDNIEQWAEKSNKPFFLWAFALDTHFPYIVPRNQQKWSNLLEMYYYNWRCNQLLDKFDIQISEREKQGIMNIYDDSIRYADLMIKEVKKRLDKYDPVYIITSDHGEAIGERGIYGHFYPSLYEENIHVPLVIGGNIEQTKTIDNPTSLTELYDMVISISETGSISYNPKDIVFATTYDGRRERNLFTYKTKSWKYHYILEDGTEQKKLFNMDGNLVEPENEVENEPVSSALGALADRRKSHEEEIIQIRESVKTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT33</accession>
    <name>V6DT33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein</fullName>
            <ecNumber evidence="5">1.1.1.79</ecNumber>
            <ecNumber evidence="5">1.1.1.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_00060</name>
        <name evidence="5" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.79" evidence="5"/>
    <dbReference type="EC" id="1.1.1.81" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="37"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="241" mass="26184" checksum="4BC4B21BADCE6999" modified="2014-02-19" version="1">MFAGTGHLPREALADHGVAVTNASGVHGPNIAEHVVGSMIAHARQFHRAYRQQSRREWRTYETTEVYGSTVAVVGLGAIGQAVVDRLESFDVETVGVRYSPEKGGPTDEVYGFDEFHEAVADAEYVVLACPLTEATRGLVDADALRTMRPDAVLVNIARGPVVDTDALVTELRNNRIRGAALDVTDPEPLPEDHPLWGLSNATITPHNAGHTPEYYERVADILADNVARLDAGEDLRNRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT34</accession>
    <name>V6DT34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4755" checksum="158A7B718F8900E6" modified="2014-02-19" version="1">MKLAPDMNGPSVTGCGYYHSVLSVRYATNNYLIKIRKAQMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT35</accession>
    <name>V6DT35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5584" checksum="C4063AA259112837" modified="2014-02-19" version="1">MCGATPTCRISVQEDRVESEVGSRRSEPKRPGCSSPETTVGGDSAAPNRMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT36</accession>
    <name>V6DT36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4723" checksum="69DE24F2A7670F0E" modified="2014-02-19" version="1">MVDAEYQYFSELLVSIDCVFCKHHLCSIQSFELFIQYSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT37</accession>
    <name>V6DT37_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative signal peptide protein</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C470_06798</name>
        <name evidence="5" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="157"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="352" mass="37299" checksum="913C8263977F6FAA" modified="2014-02-19" version="1">MPTRRPKVMSSLSRPNAVGLVGVSIVVATAVTGVVADVSTRTVLLQSSVPLAVGIGLVGYGAFLRTREVDLKPRTVLTGTALGLGAFLVVGAWFGLISARPDTSIRLSIVASLSIGSAFGTLVGSYATQLHDANERLRETNRRLKARNDQMDEFVDVASHDLRNPVNVAQGRLELARDERDSEHLRSAGRALDRMDELITDLVSLAKAGDQIRSFEPVDLGAVSEGCWDLVATRDASVSVDTNRTVRADGNRIKQIFENLFRNAVQHGGDGVTVTVGDLPDGFFVEDDGAGIPEELRGAVLEDGFSTSADGVGLGLSIVAQVSQAHGWDVTVTESKTGGARFEFTGVGTVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT38</accession>
    <name>V6DT38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="12109" checksum="B049A1BC58DD08F7" modified="2014-02-19" version="1">MIDTNALLPSLLVRFAHSLRKGTLRYRSVELGLDPEQWKRGWIAVAGSAGIGCLLWGVGSVGLRLVSSGSVHGVSLGALAAVGVYSGIFGLYYRIIRTLFAGTQAETDCVDART</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT41</accession>
    <name>V6DT41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C436_08457</name>
        <name evidence="1" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077027.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75045at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7432" checksum="267C105394C7A1AD" modified="2014-02-19" version="1">MVRSAADEVIADAGFCVEPAVDAITEILGAALDGTRPPTDPVEHARQYDWDAIAEQAEATYQRAIDGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT42</accession>
    <name>V6DT42_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aspS</name>
        <name evidence="9" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076222.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24288at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="134"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="189"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="219"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="405"/>
            <end position="408"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="434" mass="49090" checksum="7D10C4B0A7ED49EB" modified="2014-02-19" version="1">MIERIHTSDVEPDADEVAIAGHVHEIRDLGGLVFLIVRDREGLIQIVFKEEREPELFEAVQDVGAEDVVRVVGEPLESDQAPGGVEIAPTEYEVIDEADSPLPLEISKDIEVDLSTRLDNRALDLRKPETLAVFTLRSELITAMEEWFDDEGFVDIKTPLISKGGAEGGAELFPILYYNQDAFLSQSPQLYKQMLMASGYEAVYETGTAFRAEDFATSRHVSEISMFDVELAYIDDHDDVMDVQEESLRYALRRVAENAERELDLLDVDLDVPEDDFPRITFDEALDILETEYGHFPDDPTDLDTKGEKLLGEHFEEQGHPAFFVVGYPDEKFYYMQEVEGDDIASRKFDLIYKGQELSSGGQREHDVERMVEVMEAEGVETANFEFYIEALSYGTPPHGGYGLGIDRLVQKVADLDNIKEAIMFPRDPNRLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT43</accession>
    <name>V6DT43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5300" checksum="4491187CDF1180EB" modified="2014-02-19" version="1">MPLSQTVSATPKQKQQMSGLDRLSSHGLRLFEYYYWYGLILKHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT44</accession>
    <name>V6DT44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_17059</name>
        <name evidence="1" type="ORF">BN903_153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077042.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64032at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="200" mass="22331" checksum="BB59C916C030E013" modified="2014-02-19" version="1">MSGIELRDETLYVEREPNQLDELAIAFSRILDQVGIKHVYIAGYVSILAGRARSTEDVDVLIEPIDNTTADKLATTLSTEGYWGPAMPLTSMYEMLENEDPIWVAPTDQITPHIEVKTVTDEFDQASLSHALSAQIDGQSIPIGPLELQIAYKLSLGAQKDIEDAVHLYTLFEETLSAPQLETWVSRLDVEAEYDRLKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT45</accession>
    <name>V6DT45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4620" checksum="131F7946D9E655AC" modified="2014-02-19" version="1">MRPHAGRRRLLFTEHARGLQDQVSEAMEGDVRTVLALFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT46</accession>
    <name>V6DT46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_03028</name>
        <name evidence="1" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076225.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74033at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043853">
        <property type="entry name" value="DUF5815"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19132">
        <property type="entry name" value="DUF5815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="19869" checksum="68C4A4D96B17A1BA" modified="2014-02-19" version="1">MSQPRVPGGDENALELPCGEAIGVDELDLGMREYECACGETHAVVMDVHPPERFLPDFLVDVLREAIETTSEEMPEFDTPHLLGVVLEEFPEAVVAHDASENADVGYAMAWVTEFDSRRLHEVVVELVVELMEHAVSHAEDDEALSAFEQEMVEFDVSEFVEQYRAERDLEAEDPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT47</accession>
    <name>V6DT47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">IS1341-type transposase (TCE32)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C450_05970</name>
        <name evidence="7" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077024.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75656at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="177"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="295"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="417" mass="46755" checksum="542E37A4BB182818" modified="2014-02-19" version="1">MADEYVRRTAITRLSVDGEQRELLEDTITEWKRGCQIATNLAWGHCNAKSDVQSLAYDSVREDTDLGSQHAILATHQAAQAITGCIERRSQGKKVSKPTFTAPTIKYDTRTMTVFDDDTVSLATTESRVRCPLDLPDADDGYQRQYLDSDEWSVTESTLTARDGEFFLHIGFRRHKNDTERNTAEDGTVLGVDLGIENLAVTSTAYFFSGRELTHDLREFEKVRAGLQQTGTRSAHRTLGQSSGRELRHVRDVLHRASNALIDEALRYDCDVIAFENLTDIRERTGASWGHKWAFRTLYEYVEYKAESVGISVKQVGSAYTSQRCSECGFTVEENRRSRNDFRCVKCGSEANADYNAAKNIGMRYVRRGQQSSRRTGDSQLALKSGMVTPKGGFTAYPDGFEAEFTDKPHPQSAEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT48</accession>
    <name>V6DT48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5141" checksum="19F0621E9D85ABB4" modified="2014-02-19" version="1">MRDSRFEPILTNKKPVSGVLLVKTTDDTLFLVFSRVSLETLVRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT49</accession>
    <name>V6DT49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4428" checksum="8DACEB73422709CC" modified="2014-02-19" version="1">MIGVSIVTPTKPISMNNRVRQSYIMGVVDKPSYDRKCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT51</accession>
    <name>V6DT51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_14549</name>
        <name evidence="1" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076226.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125578at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8424" checksum="926EF683CC65AEF0" modified="2014-02-19" version="1">MSAGEYDRYERIRGVLAEADEPLTAREILALVEECDDCEEIDSPHRVATVLGRRAERGEIEVIAGQPYQYRLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT52</accession>
    <name>V6DT52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5484" checksum="68E56E4BCB034E83" modified="2014-02-19" version="1">MPLPAECPECGDTDIDVVSVPPSDHAYEGWQTALECDTCDERVFARELDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT53</accession>
    <name>V6DT53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_13155</name>
        <name evidence="1" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077026.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="85962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="16714" checksum="98C4E253200B9CB4" modified="2014-02-19" version="1">MDEDIEGDVGSLDIAALEEIRAEFLALDGLVDHTGFDSLLDPTELQIYVDDGIADATWCRFDIRWYQTGYYSVHHTDENGVNFRFDHHPKPDAPDRHFHHPPDADRVTASCIDVTEPRLVARAVHQLWRRVYETGETASLNTAENPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT54</accession>
    <name>V6DT54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9678" checksum="276EAE15AABF4F9C" modified="2014-02-19" version="1">MITDQIGAFTTVLRLYSAVMLLIDNDVFRVEREPQDSGNYPHPTGFAVGAQKQGMRGRTNRLVTATIDPLLVRVKGHLLRPKGQACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT56</accession>
    <name>V6DT56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5256" checksum="BB93D1931F654C6B" modified="2014-02-19" version="1">MDVCKIIHSERKFHIVVLMYDTYTIFVAHGVHYYRSIGVGVRTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT57</accession>
    <name>V6DT57_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12327</name>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="189" mass="20819" checksum="2B038D1DD468D61F" modified="2014-02-19" version="1">MRERDVTNFSAEDERTRRAIDVLVTYESDIPEARRRIERAARDCEAVIDGGPDIRIGVARYMAGPDCRLHEFGDNGILLRLRYWVKKPYKLAKVQSDVNTEIRERLGDPEADVTMAYPHRHLVFDDTSGVARVDAAADSAAVRASDPSTVRESDSPGDASSVPDAAGDVPDSAGSAFERDERPADDSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT58</accession>
    <name>V6DT58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11297" checksum="18B18433FF71E05E" modified="2014-02-19" version="1">MAAHVRVIVENAQEVDAIGVGERVRLGFQRVALRPVADDPEGAISVGGHSVERFHEGLDVRVFDQLLRDTHPSPVWPPPAPLYTFGLFKAEIIQRDIDIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT59</accession>
    <name>V6DT59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_03773</name>
        <name evidence="1" type="ORF">BN903_141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077037.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64536at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="357" mass="40841" checksum="66DFCFE51ACDEB63" modified="2014-02-19" version="1">MKVYPKIPRYDHPVVPELFFDADDVVLLEKFDGSSFRFTLYDERYASSYPDPVVNAAEGDGSLVFGTRRTIRGCHRDDLEEIDGALHRAVRCLRDGIDSDALRRCHDEHGGPLIVYAENLVYSTLDYGYTERDLPALVGFDVLPYAAIDSMTPPGNPYAETFEGFLSIDKAWRVFERIRIEDTSHDRAFVPASIIAETSEFDPDNYAVPRSSLADDIRAEGVVVRSDNYDRRVKVVREAFEELNREQFGHDPDDAETGAEQIVAMYCTSARIRKTVRSLVVEADREFGVHLVEDLYPRVVEDIWAEHWQEIMRLDFEFTPADVYPLVAKRCVTELRQMETNAELNDADPTTIWQHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT60</accession>
    <name>V6DT60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface glycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12191</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006630092.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129313at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="8095" checksum="C038DC41E426E3C6" modified="2014-02-19" version="1">MPRVKITVPEHLEMQIAQMVEEGEFLNREEAVEELLSTGIKAYKTSGPRDDDDSSGFEDEGMMGHEDEYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT61</accession>
    <name>V6DT61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8022" checksum="D2299E75212F2861" modified="2014-02-19" version="1">MIRTTDAELAERSVAAIVEEVVESVAPPGADASFAETETTNNGTEPIEESNEGKQDPKPLTDGAEVETDEAESETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT62</accession>
    <name>V6DT62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagella cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_12337</name>
        <name evidence="1" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076236.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110416at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8702" checksum="AD217AAC174315FA" modified="2014-02-19" version="1">MTEFDVHDHRHELKQLRDAGATSLWENREEMDCPVCDDAFSRLFVTEQPGTTFPENDGARFCLLRGGDAVYLFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT64</accession>
    <name>V6DT64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="11638" checksum="D72F6A3AF3FB8BC0" modified="2014-02-19" version="1">MSDASVSNGHSNTDAVINITDNLEIWEGVALRPAVIDRSAASTTVGSPTVRVRSEVAPFEPSINTEQEGVFTVDDSETVEFSFSGRNGAATSDFDGDNLRVLVAHIDPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT65</accession>
    <name>V6DT65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thiC</name>
        <name evidence="10" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="301"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="324"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK38715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="448" mass="48382" checksum="37C481B1DD4D7A3B" modified="2014-02-19" version="1">MNATQIELARDGEVTPAMERVAERENCEAAFVRRRVAEGRAVIPNNHGHDSLDPMVIGDDFSTKVNANIGNSESTSDLDAELRKLHAAVHYGADTVMDLSTGDRLDETREANVAYSPVPVGTVPIYEAVKRAESPGDITHELLLDVIGKQAEQGVDYMTIHAGVLLEHLPLTDGRKTGIVSRGGSILAQWIEENGAQNPLYAKFEEICEIFAEHDVTVSLGDGLRPGCLADASDEAQFAELETLGELTRVARDHGVQVMVEGPGHVPMDEIADNVDRQREVCDGAPFYVLGPLVTDIAPATTTSRARSARPRRRVRARRCCVTSRRKSTSVSPTRRTCETGSRRIGSQLTPPMSPTTARVRATGTTPSPRRATSSTGPGSSISRSTRSAHGTTTIRRFPETTTRKPGSARCAARSSARCASTKTRGTRTGRCPTSAARPTSTRPPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT66</accession>
    <name>V6DT66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5603" checksum="CAA1D9BB187D7EB6" modified="2014-02-19" version="1">MSLAPRSGRDLSSGKYISFSRITPLFPGLIESFSLSVSEREDVSDRGAGVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT67</accession>
    <name>V6DT67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C480_12866</name>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="228" mass="25555" checksum="75300B1D2A286C24" modified="2014-02-19" version="1">MPSRIAYHIDITLTLNYGPLDAEFSGEDREELQSELIEFVEFIDEEEALSTLPRPEENSEPKPEDKEGDQAPLSGWGDPDSSPTTQDSGSVRDEFTSLSTITGVDENTLDRLFELPENEEGVPSLNMYHFENGVLRLGDARNQRQAQASSLLMLAWEACLNEKKIKFDRLDDALVASDVETERRGSMGQAFSSDASDWFESDGSQIYLVGKGKNHARKLIQELADEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT68</accession>
    <name>V6DT68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08855</name>
        <name evidence="2" type="ORF">BN903_135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077035.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100277at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="17701" checksum="BCB0D6DEA7B8B657" modified="2014-02-19" version="1">MSNEPTDTEPTHDEFTPDPDEIEYPSTLRITSLPAQQAQAAAIERAERWEDGEEVPHVVNFEDRARLRQLLTDRRMELLEAVMDTPPASIRALADRLDRDVHDVHDDLYLLAEYDIIHFEEAGRAKKPYVPYDTVRLEVEFGLPRDDGSESAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT69</accession>
    <name>V6DT69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5953" checksum="2E0E946AA8FBEF98" modified="2014-02-19" version="1">MGPAAGGQFASLNFAVRNGHESRLSRDRYISLSQIIENEIQSEYRIWPLEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX5</accession>
    <name>V6DWX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_13046</name>
        <name evidence="2" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077385.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118181at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11407" checksum="0A1A67FFDAE9FB36" modified="2014-02-19" version="1">MIAWLGGQGNVISLLIPLFGICLLSIVDRVTETNRARRYFLSGFVLWFGCRVVLGLEQGTLVSFPRPIGLLGALSLLIGFLSLTFYGYYVVQTGRDPLASRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX6</accession>
    <name>V6DWX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Monovalent cation/H+ antiporter subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C464_08535</name>
        <name evidence="9" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077398.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64692at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025383">
        <property type="entry name" value="MbhD-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13244">
        <property type="entry name" value="DUF4040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4040" evidence="8">
        <location>
            <begin position="29"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="196" mass="20204" checksum="0CB38334EBF83C47" modified="2014-02-19" version="1">MTGALASVGPVGAPVVAQVTAIEASLFAFVVLTALFTALARDVLAAVIIFGAYSLGMAALYTFYRAPDVAMTEAAISAGVTTVLLLLTLAKTTRRDHEAAFESVNLPAVGAVGLLFGGLMLTMGDIPAVGSADAPIWSNPDVSQWYIAETYAETGVENSVMAVLAAFRGFDTFGEAVVVFAAGIAALIVLHREVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX8</accession>
    <name>V6DWX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6503" checksum="D0864DCCB196810C" modified="2014-02-19" version="1">MAARDGGESELFEYDADHGRDAGTEGNDEEFGEFDRDGGYFDHTRGGRSIIMTLSRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ0</accession>
    <name>V6DWZ0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PyrE-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_05065</name>
        <name evidence="4" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077404.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77963at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01214">
        <property type="entry name" value="PyrE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022854">
        <property type="entry name" value="PyrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF41">
        <property type="entry name" value="PTHR19278:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="77"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="22505" checksum="62CB1D55941676EC" modified="2014-02-19" version="1">MKNVDDLIDSAAELAEHGLSKGEIADELNVSRETASWLVERAGGSEADDSTAETTASADIHVDWSALGRDSTRLGYAASAMADLLAKQGEEVDLTVGVEKAGAPLATAVADRLDTDLGTYAPAKHQWDEGDIDEQGGGFSRNFAAIRNRDCYVVDDIITSGTTMRESIDAIRQQGGDPVACVVLVDKKGYDEIDGVPVYSLVDVVRVDREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ2</accession>
    <name>V6DWZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C469_14242</name>
        <name evidence="7" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078218.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15038at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="460" mass="47523" checksum="2CA079F03AB2C18B" modified="2014-02-19" version="1">MGHHDLDRSLGLYPTMMISMGAMIGSGIFVLPALGYKKAGPAVILAYVLAALVVLPAALSKAEMATAMPESGGTYLYIDRALGPFFGTIAGIGAWFSLVFKSSFALVGLGAYLLLFAPLSQGAVVYVALALGVLVVALNVSGTKMSGQIQAVIVSLVVAGLLAYVLNAGFVADAGRYTPFATEGNLGVVTAAAFVFVSYAGVTKVASVAEEVKDPGRNLPRAILGSMGIMTVLYVAVVGAVVGLSDPDVLNTGGPDGTASLTPMADGASELFGGAGVVFVSVIAVVALTSMANAGVLSSSRFPLAMSRDDLLPPALRTIDERFKTPRNSVLLTGVVLLLLIAFVPVIELAKLASAFQILVFSIINLALVAFREADVPSYQPEFRAPGYPFVQAFGFLAGIGLLTQMGGLPILGAVGIITASALTYFVYGRSRTNRTGAIGTILSDRRDEEDDEAAPTEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ3</accession>
    <name>V6DWZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-superfamily hydrolase, subfamily IA, variant 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12781</name>
        <name evidence="2" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="198" mass="21772" checksum="0D486630AE8C8387" modified="2014-02-19" version="1">MTYDTVVFDNDGVLVGRTRFDVLRDATRNAFEECGVEEPDPDDVEQMTIGATPGSVGTVCQTYDLDPGSFWRTRDDVVSRAQQQEAREGRKTPYDDLDELQDLDVEMGIVSSNQQATVDFLVDHFDGFERMGAAYGREPTIHSLQLRKPNPTTSSRHSATLTRATRCSSATTSPTSARPRTRESTPRSSAGRTAATGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ4</accession>
    <name>V6DWZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenite oxidase small subunit AoxA</fullName>
            <ecNumber evidence="5">1.20.9.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C445_10727</name>
        <name evidence="5" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.20.9.1" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050611">
        <property type="term" value="F:arsenate reductase (azurin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="8908" checksum="AE7DA308D0599E7F" modified="2014-02-19" version="1">MGCPVQGQVKPEREMAGPCPCHYTTFDLSKGGLVVSGAATTDLPQIRLDVEDGDVYATGVDGLSYGYRDNLRDGEPVTAEETEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ5</accession>
    <name>V6DWZ5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl18</name>
        <name evidence="6" type="synonym">rpl18p</name>
        <name evidence="6" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078224.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108717at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_L18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_L5_euk/L18_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="PTHR23410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20189" checksum="6F1C5CEA2E703E85" modified="2014-02-19" version="1">MATGPRYKVPMRRRREVRTDYHQRLRLLKSGKPRLVARVSNAHVRAQLVTPGPDGDETHAAASSEELGEYGWDAPTGNLPSAYLTGFLAGARAVDAGLDEAVLDIGLNTATPGNKTFAVQEGAIDAGLEVPHNDDVLADWSRTRGEHIADYAEQLDEPLYSGEFDASELPEHFDSVLATIQEDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ6</accession>
    <name>V6DWZ6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_12826</name>
        <name evidence="5" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077408.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116879at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="310" mass="34038" checksum="1ACE0BADD9865CF3" modified="2014-02-19" version="1">MSDQEQADAADEAEETETETDAGGLEDGDFVRVAYTIRTADDGRVIDTTDKETAEDAEIDVDEYDFEPRIIALGAGHVFPSVEEAFVGGSVGDEGTVDVPAEDAFGEYDPDEVETVKADKIPEDDRYPGAQIQIDNRQGHLETIIGGRARVDFNHPLAGEDLEYEYEILEAIDDREEQASGMLGMYLQEAPEVRIETVTEEEETVTEDDDGEETVETEEVEKDVLYVTATQAMQMNQQWMFQKQQIAQDLMDRLDLDRVVIEEVIEGGGMGGLGGMMGGMGGGAGDVDIEEALEDVDVDADEIVDEIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ7</accession>
    <name>V6DWZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01868</name>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078262.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80006at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="22526" checksum="FAD77E6349BF2353" modified="2014-02-19" version="1">MVSDDTRAVSDVDDAHAVPDDDDARAVSDDLDAFVDENLDRYAETQGVLPKRLDEFGETYRSQGHLTRDQLYEIAYESSTRSAYHVEKNPEARCREVTRNARAVDGDFSTIHLITGLAGFKAPTASCVLAALDGDRHAVVDTRVWASLERLSYLDGRKESFDAADYVAMIGPIREIAAETGHRAVDVGYALFAHDAHVREGTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ8</accession>
    <name>V6DWZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase FAD-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09958</name>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="15630" checksum="A99E585B48E76657" modified="2014-02-19" version="1">MDTTATVESVASVGPDTYALRFRAPDGFAAEPGQFVKLGTEIDGESVARFYTLSSPRVGETFEVTVGIDPDEGGDFSAFLADAEAGTEMTLSGPYGDQHYDGEARAVVIAGGPGIGPAVAIAEXXXXXXXVADAEAAVDAAGGDADAAKVENFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWZ9</accession>
    <name>V6DWZ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MIP family channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_15469</name>
        <name evidence="7" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077807.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45822at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="255" mass="26512" checksum="5BEE706579816C7E" modified="2014-02-19" version="1">MNPYVAEVIGTAILIIFGGGVVANVVLDETKGNGGGWIVITWGWAIGVFMGVFTISQVSGGHINPAVTIGLAAAGLFDWTQVPLYVAAQTLGGFLGGIVVWLAYRDHFAVTEDEGAKLAIFSTAPEIRNYSSNLITEIIGTFVLVFGVLYLNSAGFLNETSGEILQTITIDGQEVGFGLGALSALPIALVVLGIGLSLGGPTGYAINPARDLGPRIAHAILPFPHKGPSDWAYSWVPVVGPILGALLAAGLYHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX95</accession>
    <name>V6DX95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5371" checksum="9CE6DB172EC51C0B" modified="2014-02-19" version="1">MLKPSVVDICTVSIAQYRETMHRIVALIIELGFSTKDPIVILQSISQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX96</accession>
    <name>V6DX96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Archaerhodopsin BD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">aopbd1</name>
        <name evidence="12" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="entry name" value="PTHR28286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00950">
        <property type="entry name" value="BACTERIAL_OPSIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00327">
        <property type="entry name" value="BACTERIAL_OPSIN_RET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK39990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="258" mass="27732" checksum="D53FD865096E6FAC" modified="2014-02-19" version="1">MDPIALQAGYDLLGDGRPETLWLGIGTILMLIGTFYFLVKGWGVTDKEAREYYSITILIPGIASAAYLSMFFGIGLTEVTVGGEVLDIYYARYADWLFTTPLLLLDLALLAKVDRSTIGTLVGVDALMIVTGLIGALSHTPLARYTWWLFSTIAMIVVLYFLATSLRAAAKERGPDVAKLFNTLTALVLVLWTAYPILWIVGTEGTGVVGLGVETLLFMVLDVLAKVGFGFILLRSRAIIGGTEAPEPSAGADAQAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX97</accession>
    <name>V6DX97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_08177</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5759" checksum="6A9B4ADC4AB270E0" modified="2014-02-19" version="1">MGLKEDTANGVISLGIGVAVTWFTASDGEHDTTDLLVAVAISSFLSGFFTSYFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX98</accession>
    <name>V6DX98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10958</name>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077886.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99874at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025098">
        <property type="entry name" value="DUF4013"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13197">
        <property type="entry name" value="DUF4013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="22848" checksum="71C2F3BF0901B251" modified="2014-02-19" version="1">MRPSIAAVSYPVAGDAAERPLLAVWLLLALSVLVPVLPAVPVVGYLVRVLAASERGDSLPPFLADGRTLLRRSLGGLVVCLAFLGVPFAALLVTLYGVITLEPGADAPVVVILAGSTAVLFMGIIGLYLVPISLTTYGRQGSLRRAFSTDSLRPVAGHAAYFFGWTLGFTALVVTVGVGGALFTLSRIGPLAGTFVLAYGLLVTAYLWGRAVERARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0J0</accession>
    <name>V6E0J0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08861</name>
        <name evidence="3" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629442.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000034.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130128at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043902">
        <property type="entry name" value="DUF5786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19099">
        <property type="entry name" value="DUF5786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5786" evidence="2">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6700" checksum="2B0E2C5A93F39531" modified="2014-02-19" version="1">MGFGSYDESEQENQDLDADFDDEDGVQAAQETHEGSVDYEPGASNDELLDRLQEIKSEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0J2</accession>
    <name>V6E0J2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
            <ecNumber evidence="2">1.1.1.302</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03591</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000033">
        <property type="protein sequence ID" value="CDK41100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7230" checksum="F0FECB06B2136195" modified="2014-02-19" version="1">MIFSCFEAGVVDELHVYVGSMVVGGRDAPTLADGSGFIEAFPDLTLTDVERLDDGVVLSYDVEDDDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0J5</accession>
    <name>V6E0J5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-carnitine dehydratase/bile acid-inducible protein F</fullName>
            <ecNumber evidence="1">2.8.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_14400</name>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.16" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000035">
        <property type="protein sequence ID" value="CDK41113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033608">
        <property type="term" value="F:formyl-CoA transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9560" checksum="4708B974284084C9" modified="2014-02-19" version="1">MPASRVRDVSEVFADPQIEARGMLAEADHPTAGTVTFPGSPMYFSRTPTTVRRHPPALGEHTESVLREYGYGDGDIDELRERGAISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0J7</accession>
    <name>V6E0J7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_01234</name>
        <name evidence="3" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004598787.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="55594409"/>
    <dbReference type="OrthoDB" id="110723at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9992" checksum="96ACF0405F45AA09" modified="2014-02-19" version="1">MTVRLLDFHAEWCGPCKTQDPILEEIQEDLGDAFELQKVDVDEEQDVANQYQVRSLPTLIVENDDGVVDRFVGVTQREDIEAALTEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0J8</accession>
    <name>V6E0J8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isocitrate lyase and phosphorylmutase</fullName>
            <ecNumber evidence="4">4.1.3.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_06437</name>
        <name evidence="4" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.32" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000035">
        <property type="protein sequence ID" value="CDK41118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078461.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000035.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="53531at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047529">
        <property type="term" value="F:2,3-dimethylmalate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="347" mass="39042" checksum="99D92CA613D27833" modified="2014-02-19" version="1">MNPNELDDDVFDRDIDNPAGRKLRELFDEQEYTFAPGIYHALDARLAEMAGLDAAYMSGYSTVLGQFGFPDLEMVTMTEMVENAKRMVEATNLPVIADCDTGYGGIHNVRRAVREYEKAGVAAVHIEDQTSPKRCGHIAGKQIVSREEARSRFEAAVDAKQSEDTVIIARTDAYGSANGDWEEHLERGRIYADAGVDLVWPEMPDPSREDAVEYAETIHETHPDLDLAFNYSSSFEWGAEEDPLTFEELGDLGYQYIFITLYGLHSGAHAVYEDLSNIAENDEQAQFDLEERYIGHETESHHELSFVPRYQDIEAEFDPEARKRQEESAGFTEEENDPITASEGGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0K3</accession>
    <name>V6E0K3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_07851</name>
        <name evidence="3" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000037">
        <property type="protein sequence ID" value="CDK41123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8574" checksum="D9EEC4FBA9D3628C" modified="2014-02-19" version="1">MAFAVPWPLWGVNRVVAGLPVWIWWHVAWLGLCAALFALFVRSGAWERGMGQRSTTDSGSGTPGTASGTAKTADAEGDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0K6</accession>
    <name>V6E0K6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_08901</name>
        <name evidence="1" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="4986" checksum="76DC51D71BD19362" modified="2014-02-19" version="1">MTTVHFTCSDCAQTIEVNDAMRETILEAGCPVCTAAAAEDDFAVTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0K8</accession>
    <name>V6E0K8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13192</name>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000037">
        <property type="protein sequence ID" value="CDK41128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="6011" checksum="B3EAEDA6F694B5F4" modified="2014-02-19" version="1">MRSEAEIREQYEFLREQLDDEEMNHRGVEELFTHYKRALGWVLEEEHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0L0</accession>
    <name>V6E0L0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000035">
        <property type="protein sequence ID" value="CDK41115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8244" checksum="5873E3EBD66328E6" modified="2014-02-19" version="1">MSPVGDENKVVASVVNTSEVPAARYDDALTKDTTTEAPAARTPAARCAPRSRCSLRCLRRHQNASRSDWLTRASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0L3</accession>
    <name>V6E0L3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase E1 component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_02203</name>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000039">
        <property type="protein sequence ID" value="CDK41133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6548" checksum="0408134BBD994F52" modified="2014-02-19" version="1">MGHESGTEAIADGNVFPLNIGIAAHLPHAVGAAWAFDHRDEGRVVACHFGTARPARATSTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0L5</accession>
    <name>V6E0L5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M28</fullName>
            <ecNumber evidence="4">3.4.11.10</ecNumber>
            <ecNumber evidence="4">3.4.11.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_02604</name>
        <name evidence="4" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.10" evidence="4"/>
    <dbReference type="EC" id="3.4.11.6" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000036">
        <property type="protein sequence ID" value="CDK41120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="3">
        <location>
            <begin position="135"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="361" mass="37958" checksum="5678DEF62938F565" modified="2014-02-19" version="1">MTAPLVDVGDGTDEEFAAAGDALEGAVAMASSLTPESHDRWIHRMEKYVAAAERGAVGFVFRNHIEGALPPTGEIGYHNRPGPIPAVGVSKEVGDRLSRLAVGAGKGGGVGSEGDDGPTVSLDVDCRNEPTTSVNAVAEVGPDTDEAVYLTAHVDAHDVSDGANDNGAGSALVVEVGRLLASVEDDLDTRVRLVTFGSEEIGLWGAYHAAETTPREEIACVVNLDGACSSRNLRVGTNRFDGMRSVFEAVVDAFDAPLATGETISPHGDQWAFVQEGIPAVMVSTTSDQSGRGWGHTHADTLDKLDSRDLGEVATLVAASVYRFATGEVEAAHRSRESIRDAIDEGYVEELKTGGRWPYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0L7</accession>
    <name>V6E0L7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04747</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000040">
        <property type="protein sequence ID" value="CDK41138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078481.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000040.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116265at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007254">
        <property type="entry name" value="DUF373"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38815">
        <property type="entry name" value="PTHR38815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04123">
        <property type="entry name" value="DUF373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="369" mass="38285" checksum="F340EBE866BB28A9" modified="2014-02-19" version="1">MLLVLCVDLDDDLGRKTGIPTPVIGDEDVTEAAVALATADPEDSDVNVLFQGVNVHDELAAEGEVVEVAAVTGVDGPDVKANRAVGQEVDRVLAELSTGEEVSAVVITDGAQDESVLPVIRSRMPIDGMRRVVVRQAQDLESLYYTIKQVLADPETRGTILIPLGVLLLIYPLVVVANLFDVAGAAVLGILSGAVGLYSLFRGLGLEETVDGAAESVRNVLYTGRVTLVTYVVALALIVVGGVQGIDTVDAVRGVQGGSLAGGTALAAFVHGFVQWLSVAGVTSSLGQITDEYLAGRFRWRYLNAPFYVVSIAVVLFAVSGFFLPDAPGVTALGLSELAMALAAGTLIGVLSTLAFAVAESQLPSADPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0M1</accession>
    <name>V6E0M1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_09537</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000037">
        <property type="protein sequence ID" value="CDK41125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004597247.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000037.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38951235"/>
    <dbReference type="GeneID" id="55595103"/>
    <dbReference type="GeneID" id="64826576"/>
    <dbReference type="OrthoDB" id="124778at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="10986" checksum="E8945B30BC60A2AF" modified="2014-02-19" version="1">MYDLTGFQRDLLYVIAGLDEPHGLAIKEELEEYYEKEIHHGRLYPNLDTLVEKGLVEKGQRDRRTNYYTLTRRGRREIEARTDWEAEYIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0M2</accession>
    <name>V6E0M2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MIP family channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_16209</name>
        <name evidence="7" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000041">
        <property type="protein sequence ID" value="CDK41143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078485.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000041.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45822at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK41143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="255" mass="26347" checksum="E58AC96859AE5CF7" modified="2014-02-19" version="1">MNPYVAEVIGTAILIVFGGGVVANVVLDETKGNGGGWIVITWGWAIGVFMGVFTISQVSGGHINPAVTVGLAAAGLFDWAQVPLYVASQTLGGFLGGVTVWLAYKDHFAITEAEDAKLAIFSTAPEIRNYASNLITEIIGTFVLVFAVLYLNSAGFVDGTSGQILQTITIDGQEVGFGLGALSALPIALVVLGIGLSLGGPTGYAINPARDLGPRVAHAVLPFPHKGPSDWAYSWVPVVGPILGALLAAGLYRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0M5</accession>
    <name>V6E0M5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rh family protein/ammonium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C465_15662</name>
        <name evidence="9" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the P(II) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000038">
        <property type="protein sequence ID" value="CDK41130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="8">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK41130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="231" mass="23790" checksum="397296E6FA7B0BE7" modified="2014-02-19" version="1">MFPVHGSAGVLGVLALPFVSINGFSVDLLVSQVIGVVVITAWTVIATAIVFGAFKALGQARVTPEHERDGLDVSEHGVETYPEFGRANVATDGGPSVVDATESANDSPRADGGEESGAEIKMVTAVVRPDKLGAIKQALAEVNAPSLTVTNVSGRGSQPAKKGQWRGEEFTVDLHQKVKVEVVVADIPADEVAEAIAGAAKTGEPGDGKVFIMPVEDALQVRTGATGPEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0M6</accession>
    <name>V6E0M6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000042">
        <property type="protein sequence ID" value="CDK41148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6524" checksum="DC5D636BB70FAA20" modified="2014-02-19" version="1">MTPVGGPLLAYLHDVPFEPAQRTVGRGRRLDLEFDVQTPCRGVIRSPGFGYVVLCVHTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSN3</accession>
    <name>V6DSN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="8877" checksum="70DD121E836356D0" modified="2014-02-19" version="1">MIAYYLTTREYTPGSVVMGFLIGGLVFIIGNAILGVAVTNLFVSGSGVERSLLGHMQNSLPHGMRLFIGGLLGVAGALVVEEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSN4</accession>
    <name>V6DSN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6537" checksum="7C9CDA93E8F6EA1A" modified="2014-02-19" version="1">MIVVFGMNHLRSASLPSTFVAKSRVSFPDDTDGLESSALTSSVTYREISCSPARADALGDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSN5</accession>
    <name>V6DSN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_15044</name>
        <name evidence="2" type="ORF">BN903_175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076955.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91082at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="140" mass="14536" checksum="5B7EB89EFF79A70D" modified="2014-02-19" version="1">MCTQGCSGGTPARTEESPSPVRIIHGSIGLMLLALLPLFLFVGTAAAQSDPGSAFCDSNMAGTIQNIFTIIQFGGPLIGGVLALGATVAIPFARRSDWKKEMKSVRNQGLLWGVIVAPLGTEIVQFILNNVVVGGTSCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSN9</accession>
    <name>V6DSN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C486_17155</name>
        <name evidence="2" type="ORF">BN903_154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076888.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109353at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="24328" checksum="868A414EBE04A2E4" modified="2014-02-19" version="1">MGHRALVAYERTDGQYTLHYSHWGAANLKLNHRISAASPFGGEDTDSRWAKQLLAELVDGLEADAVDGYLVDEDRPSTIVEPKPRATGLTLEEIVADHLDYLHHEAFYVVSPTFKVTAYRTLWFGLQYDSETVEEGETVGNGALATVRWDDGEPVGDGHLQGQFAALKDVVGDMLDKGVFTPSAARQYLKRKLAERVGDQQELLIPTGESPFEKASQNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP0</accession>
    <name>V6DSP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6232" checksum="64C3BBFE74EA7399" modified="2014-02-19" version="1">MVYTCRRRYLKLPRWPLSGEAITPSVPLQTDLSEPALFSITEPSSKYRIFETSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP5</accession>
    <name>V6DSP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_00965</name>
        <name evidence="2" type="ORF">BN903_245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="8407" checksum="C486E5B372623CAE" modified="2014-02-19" version="1">MSKTSTLLDLVCAHRRQMKVALAVLIACGLLLAFSAVFVRPGDDAWPILVIDAVLVVGGFVAFASTYWYCTKREMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP7</accession>
    <name>V6DSP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C437_15089</name>
        <name evidence="1" type="ORF">BN903_185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076912.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16853at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="406" mass="46474" checksum="4A58DC24DCC473B8" modified="2014-02-19" version="1">MPFRALADGKIVTPTQVDDHQPVECPECRGILYPRDGKHRARHFFHAADDAAESCSMASQEESDTHARCTALAVATLADQYPNTARVGAEIKIDATGTPTTPETRRADALVEFNKENPFFGGGLIIEVQHKHHSKDIEGTTHDYLSAGYSVAWLESEDIGDEQLDYQVVDEAFRADDGSAFSIREYDPWEFDTRVEANLNWEEKSQGCHFVEEYGSHNWSQVPGYAHPDRYEYEYCWWCGSRRRYDHELTRFVYDYEGVLAPEVDIEVLRDAVIPYPDVADNFDDWKNSDSFGRERSFEGALAKRTDVAPCRGPHGIHEWRRKEVIERRYDDRVDVALWECQHCPVHLLTNHTGHGETEAAILFGKAPNPDWGLDHLNGNPQKCNNRSHHKQADWDYCPDCFQIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSP8</accession>
    <name>V6DSP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C485_00425</name>
        <name evidence="1" type="ORF">BN903_164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076895.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64032at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="23302" checksum="320B6695A61A3A51" modified="2014-02-19" version="1">MELSDDTLTVSRELSALDKDVLEFTQILDTCDVNYVIVSGYVAILTGRSRSTEDIDVILESLSEEETEQLVTKLKDREYWGMAMPLAEMYSMLSEGSRIRIAEDGEMYPNFETWFVSNDVEREALSNPLTVTFEEGQIKISPLELQIAYKLRLAQAADSLSGKDFEDALHLYLTFEERFNTEQLETYVNELGVEDYYAELKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSQ1</accession>
    <name>V6DSQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pNG6014</name>
        <name evidence="2" type="ORF">BN903_190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076916.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112335at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="15086" checksum="4D5D8DAF2E6995AD" modified="2014-02-19" version="1">MSDGWGDASGIEGNYEEEDDEVDSGETSEVSETVETSSSTETNDSNSTSETNETSKTKTNIKDEWNGRTIYIPDGVLNEMEDTYLESQLKLRKAGQDEFKKNRHFYPLLVQFGVEALSEADAEEIQARLSELGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSQ8</accession>
    <name>V6DSQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5588" checksum="5ABE5998BE863573" modified="2014-02-19" version="1">MRTRANDYYDAVRSRKGDRIGRAGAADVPVAGARRGTADRPRETTGKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT00</accession>
    <name>V6DT00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_00994</name>
        <name evidence="2" type="ORF">BN903_330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076414.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125511at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021377">
        <property type="entry name" value="DUF3006"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11213">
        <property type="entry name" value="DUF3006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10784" checksum="A4958268433C2A68" modified="2014-02-19" version="1">MTAIELPDGEYTAVVDNVEDGFATVFFERDGEEAGNAVLEASRLPPDGRHADAILSVVLSEGRIEAATYKPEQTESRAEEAQDRFDRLSKRPPSDEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT01</accession>
    <name>V6DT01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">8-oxoguanine DNA glycosylase domain protein</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_00457</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076204.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83981at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="140"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="308" mass="34433" checksum="E8CA0E74CA76CD0F" modified="2014-02-19" version="1">MERGAIDVGDLAGPFDLQATLESGQSYLWNRADGDTYGELHAHGGDAWYETVVDPIPAVTDERVAVRVRQEGGVHDGTLRWEASTDAEPLLTHLLRLDDDLDAILDATPDLSLLERAYDAYEGMRLTRDPVFPCLISFICSAQMRVARIHGMQRRLRETYGDAVALGDETYRAFPTPEQLAARTEDELRDLSLGYRAPYVQRTAEMVASGEADPREAADLPYEEARESLTRFVGVGDKVADCVLLFSLGFLEAVPLDTWIRTTIEEYYPDCDRGSYAATSRALRERFGDEFAGYAQTYVFYYLRAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT02</accession>
    <name>V6DT02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS240-type transposase (ISH102)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_06237</name>
        <name evidence="1" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="12296" checksum="1DA3018BBDE9377D" modified="2014-02-19" version="1">MKLSIQLHLSVLSISNIIFCFLKYSVLIEVDRPFITGPQANLQSETDRNPNPVVVDETVIRLNNEQYRLYAAVDTDSNDLIYTLFEPTKTNIILDQFFSELHKKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT03</accession>
    <name>V6DT03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C463_02186</name>
        <name evidence="5" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334933.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="313" mass="33888" checksum="15AA2BF4B53F6D58" modified="2014-02-19" version="1">MPRPSVVLIVEDEPDLADQYAAWLDDDYEVRSTIDAETAREEFDASVDVVLLDRQLPDASGAGLLGRLRARDGDFAAAMITGIEPDFRVLQLDVDEYVTKPVERDELRALVERLTDRRAVEEAVDGYLSLLAKKRASEADSSHGEPASDSRSDSSSGELLARRRQIESLLVRLGTPADESSAMFPDDEGRVDGTGETGAGEPPLYRSRPTEFYGLWLLAALTYGVGDVVSTLYAVLGVTGIDEANPVVGSLLTTFGIPGFLLLKFLVFLVLISVSVQGARTVDRFSYYWPPVVMALLGVGLTAWNLTTIAGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT04</accession>
    <name>V6DT04_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C469_13065</name>
        <name evidence="5" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="29028" checksum="499BCCC2F1CF02D0" modified="2014-02-19" version="1">MMPVLDKPTIQYVVEEAVEAGIDDILIITGRGKQAIERHFDKSYELEEALEADGKLDRLDRVQEIADLADIHYVRQKERDGLGDAVRYARKHVGDEPFALLLGDTIIENDTPCTETLIDEAEAHETSVLSLERVPWEQVPSYGVADTGDVESSAGSFPVNDFVEKPPQDEAPSNLAITGRYVLTSEIFELLESTEKGVGGELQLTDAIRELDDVRGVELDGDRYDIGNIPSWLRANIEMSLHHDDGEINEAVEALLREQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT05</accession>
    <name>V6DT05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="11072" checksum="04A766BF6A5B5088" modified="2014-02-19" version="1">MPIVYIRFSISSHLTHVLFPSTSNSKLVPRRYLSRQPVRADKVGLLLSAGPNTDPLPHSLLLRYVRVRKSQCARVVNPDFDSFGFIEILFFRRFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT06</accession>
    <name>V6DT06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C488_21287</name>
        <name evidence="3" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.57" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077098.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75045at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="379" mass="41542" checksum="12A5E0E7426742AE" modified="2014-02-19" version="1">MQIAFVTNVVYPFVTGGAEKRIHEIGTRLAERGHDVTVYGRHFWDGPAEITHEGITLRAVAPEADLYADDRRSITEALDFAARALPPLRRRLSDDEHDVVVASVFPYFPVLSTKLASLGTDTPLVTTWHEVWGDYWDEYLGRLAPFGKVTEHVTARTPQHPTAISGVTADRLAAIGPDRGRIEIVPNGIDVKQIHNAPLPEQGYDILFAGRLIEHKNVDLLLEAFDRVAVDTDATLGIVGDGPERDALEAQATELTHADRVEFCGFLDDYEDVLGHMRAADIFCSPSTREGFGLTFAEAMAADCTVIAADHPDSAADEVIDDAGFLVDPTVDAVTEILDRAVGGARPTTAPRERAQQYDWDAVATQAETAYRRAIDGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT07</accession>
    <name>V6DT07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_12341</name>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="283" mass="29894" checksum="98C65739F7BC49DE" modified="2014-02-19" version="1">MDGPNDADATVRLACGDRPSVRDGITAERVVSVLFGTDVEAWRTGWQRTAAGPPSREAVVDASDVTRSGAASSTQVMANGGLAYTILGREAGNERVLDALASHLDGAPPGTVDLVIDDLAPVAARDGPDSAVAFTDRFVARFAERANRIAIGYARGGPAEVVSRIGDRVDSLVGTDAETVAVERLSREDPTTFGYVRRHWAEAKRGIEACDRNYPQSKQVHAALTDPETTPRTLGATLSGLVTLGALDTWSETVGPTRYDLTAYRPDRAWAIGAAVETGASDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT08</accession>
    <name>V6DT08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6380" checksum="B1269436B052C534" modified="2014-02-19" version="1">MVSDETHSTPTPPLPLFQSPLAERCICLHPHRFRCYDREVDLSTNLIVNSGTAGVSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT09</accession>
    <name>V6DT09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_02201</name>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077006.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64670at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="347" mass="38754" checksum="3C6B1F1A4A641117" modified="2014-02-19" version="1">MADSTGRDSGPPIDADAFQEWVEHTAETRDIDEQELLNQLVSAFWILDEMNGVTEERDPVGGGTSPYPPELSDPDRWSVGDAEAASGVAADRSGSSSAGRDGDEDETASDDEAADDRSQKETEPVDGPEKPESGAVADEIQSLRESMYGQLEMIQTVTKLRRQVSDLSLDVEQQRSRQEEFADRYSDNLTRLHSRVETLDDRLDEGALDETELDRIAEEFSAEIDRLDSTQREFETWIDEEFDEIEGLFKQLLDTTGTLEERLDTLDTAVSTLRDDEETDRLAALRRDALDLGTDTGRCERCETTIDISMLDEPRCPDCDATFVAAEPAESWNPFAKPVLRTAERVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT10</accession>
    <name>V6DT10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4952" checksum="A96C9960D7C74385" modified="2014-02-19" version="1">MCGVYRLVCRPRHPLFGTLASRHANWPSSRLAKRRENRKSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT13</accession>
    <name>V6DT13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
            <ecNumber evidence="3">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_17253</name>
        <name evidence="3" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16670" checksum="78988B88D292D92E" modified="2014-02-19" version="1">MNLADSRVLVTGGAGLVGSHLAASLLDRGATVRVADDLSKGTRDRVPDGAAFVEADLTDPADVARVVTDDLDIVFHFAAYTDTNYDDDRALFEDNTAMTYNVLERMREVGIDRFAFTSSSTVYGEAPGRRPRTTRRWNPSPCTAPRSSRTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT15</accession>
    <name>V6DT15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4500" checksum="8D4323F941F7AE3F" modified="2014-02-19" version="1">MIGLSIMPLNVFSELSNLIDVSTVLSSMCGANYYGSLYSHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT16</accession>
    <name>V6DT16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C444_16918</name>
        <name evidence="2" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077029.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79384at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="145" mass="16944" checksum="63F4253C71B9E136" modified="2014-02-19" version="1">MPDDVTDPPDRGPIDSELLDRIATHLSRSNRFNNIETRPVYAPNAVIADYDLGYFPNGVTRASLRIRWFETDDFSVHYSEQYRTGNAWECHWDSHPNDHNTREHFHPPPDASTPGTDEEYPEDWRDVLATVLTRLDDRIEAFWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT17</accession>
    <name>V6DT17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5246" checksum="17E40A72A73CF610" modified="2014-02-19" version="1">MRIGFNMNENLQSQSESRENSGQRREKQQSESEMSINRRTETAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT18</accession>
    <name>V6DT18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7707" checksum="B0A4A53FB7D7CD37" modified="2014-02-19" version="1">MNHSDVHTPDRYFLSLDLNTDELRSLSFVETKHLKTGRAANERFLVTHPWTTTQDASVDHRERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT20</accession>
    <name>V6DT20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_2138</name>
        <name evidence="2" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="295" mass="33611" checksum="56959ACD4F301EC6" modified="2014-02-19" version="1">MEPKVSIVLLNWNNFDDTDDCLESIEKQDYGQLQTILIDNGSDDGSFGRLTKDHNLVSTRLKSNIGFPAANNIGIEIAMETDSDYIFLLNNDTILPKDDVISKLVSVAEGRENLGILSPIITHYPETEQIWFAKGVINKYLGETKHKYKNRNIGELDSKRLINNDRMTGCAMFVPDYVFEDVGKLESDYFLLESDTDFSLRVREQGYDLITDSTNVIHHKVSASTDDQFELSYYSSRNRWRLINDSSTFYRTAKLAYVLGTIRGIFRRIKSGEIRYVPDLVRGAIHGIIGRDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT21</accession>
    <name>V6DT21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="17721" checksum="EB40751B779DADF4" modified="2014-02-19" version="1">MLLTTAIRPDQARTPLSCRTADKATEMADLSSADPRRTRTVLSRSVGRSGRRPEVETASHRHPNGVNRGRLSKNAVFKILLEDRPVTGPVERAQRYDWDASPYRADGTSTRRGVKDKRINHHQETHNRCDPDCQQLRIKDDNTNAVRGGKRQWKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT22</accession>
    <name>V6DT22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6547" checksum="A0864C2B82E67099" modified="2014-02-19" version="1">MGWGYCASHHSPFATNAPTASAVSGHLCLVHVLVPDTPMLTAEPMGWGVPRSPSTFRPGTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT23</accession>
    <name>V6DT23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5790" checksum="1DA665E2DEA9B539" modified="2014-02-19" version="1">MVAGRVLLVRRVRVDRGHQCPRLRVRFLSGVDRASLEAAVVGAVAVAVVGSVAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT26</accession>
    <name>V6DT26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbD</name>
        <name evidence="2" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077017.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43377at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="298" mass="32314" checksum="20B7A5BCE18A0054" modified="2014-02-19" version="1">MRLLVVGANGLLGSNVVRAGQRRGWDVCGTYHSMRPDFEIPLVQFDLQAYDEFEAILAEFEPDVVVNCAAMTDVDGCETDPETARVLNGDAPGALAAQCVSHDVQFVHVSTDYVFDGTARDPYPETADPNPVQVYGESKLAGERAVRETAPAALVARLSFVWGIHRSRNELTGFPAWVRGQLQDGDEVPLFTDQWLTPTRAGQAADVLLDLIDHDASGLVHVACTSCVTPYEFGEVIAEVGGYDAELLGAGSMDDVDRDATRPAHSCLDVSRVESTLERAQPTLQEDVDAVRETFESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT27</accession>
    <name>V6DT27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00040</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076215.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122226at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036473">
        <property type="entry name" value="Mopterin_CF_MoaD-rel_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12343" checksum="2286C546CC8E20A5" modified="2014-02-19" version="1">MSDDGSASVEEADGDASAPGLPPAEEGWERETVAYRGISRRLAAHYLRNLGGELVGTDDPAEATRVDGDGWRVALSAEKVTAAAAIKITEVTAEFAGDPDALADLLPKYRQKAMRAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT28</accession>
    <name>V6DT28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4736" checksum="AF95A07D89C7589E" modified="2014-02-19" version="1">MNDVDTQHYPADSREDALRWESYRYWDEPPEVSFCRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV0</accession>
    <name>V6DWV0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C466_07280</name>
        <name evidence="5" type="synonym">cetZ</name>
        <name evidence="7" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CetZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077775.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="23481at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="6">
        <location>
            <begin position="2"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="112"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="390" mass="41831" checksum="5986FABEA331B856" modified="2014-02-19" version="1">MKLATIGVGNAGSKLIDQMIEFEVETGRNLCRHALIINTARTDLAKPENIPEDRRVLMGDTHRKARGHGVGGDAEIGAEVATTDIDEIRRVFDDVEIHEVDAVLVAAGLGGGTGSGAAPVVIDEIQKMYDEPVYGLGVLPGKYEGGRPALNAARSLQSFVTKVDNFIAFDNDAWRSRGQTIEQGYEEMNEELATRIVTLLAAGEVDESEVGENAMDSSDIMRTLDTGGVSSIGYASTELSPAKQGLLSKFNDSEQSEDESTDAAKIKGLVRRAVNSRLTVPCEVSSADRALIVFAGPPEAISRKGVESAREWLESAADTVDVLAGDDPRPGSSTLAAVVLLSNVTETPRIDEIQNQAVDAQNKIREQDAVREEEIQSLITDDDNDLDPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV1</accession>
    <name>V6DWV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HSP20 type chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_03669</name>
        <name evidence="3" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078245.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100431at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040612">
        <property type="entry name" value="ArsA_HSP20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17886">
        <property type="entry name" value="ArsA_HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="2">
        <location>
            <begin position="34"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13753" checksum="1DC5F4A6D314D581" modified="2014-02-19" version="1">MDRDDRDDPFGDFFEEIERMMNEMANANGPSADDAGFGSDTHVDAYATEESVRLVADLPAVSKEDLSLRCDGDALTISAVSDRREYDETVDLPAPVDEHSADATFNNGVLEVTFDRADDSASIDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV2</accession>
    <name>V6DWV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12034" checksum="EC0DF6E3135920BA" modified="2014-02-19" version="1">MRISGEISGIAVTSPASFVIGAGLNGCPERVSNQSEDHDAEHRITSYNVCYTKLLRPMSVVISRGRQGTQGIGXXXXXXXGPRAGRGRARQRVEHGPRPVRPRRGVRHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV3</accession>
    <name>V6DWV3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1524 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NJ7G_4323</name>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1524" evidence="1">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="17113" checksum="A8C76D5F53648910" modified="2014-02-19" version="1">MRVLVSTKQAVEEAVDRSRYDTNSEGALFTNNSVVAILGLIEEAYAGDDISGYAVDHIYPKNKSREINEAVGDEVDLNRIGNLQLLPQGANEKKSDQLPKDWLYNIGESSSSRVKEINLYPDVEPEKENAIEFIEQREQMITDYLLQKYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV4</accession>
    <name>V6DWV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13692</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078176.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121980at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="7709" checksum="F5CD45474587BB1B" modified="2014-02-19" version="1">MSHQSGSPRFDLDAAFKAFGAVGIAISVALVVAVFALTDPFGEYVTASPAVFGTLLSVVLVAAVGYTTYALRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV5</accession>
    <name>V6DWV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA (Guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.216</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_12767</name>
        <name evidence="8" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004809">
        <property type="term" value="F:tRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="PTHR10631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 7" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="197" mass="21701" checksum="62E5569C635C4F2E" modified="2014-02-19" version="1">MGLRTLVSALVRTAARYDKAARPIVSHVSRHYARTYLELESGARAADDCLEALGHVDHCEDCLWRSATHGRIADPVDACPECGSNRVLTAGPIWLGPVADPDFARAVRREVTDDMGEAKRARKLLGTVARELDTPTHYDQHRLYKQWGEPAIGMDEFVERLRGAGHEASRAHYRGTAVKSTASIPQMREAVLGTDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV6</accession>
    <name>V6DWV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase, IS605 OrfB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C484_17034</name>
        <name evidence="1" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6604" checksum="368BE0A4D09CE9C9" modified="2014-02-19" version="1">MCDDCGTTANADVNGAENIRQKVSPSSPNLSVNRSNGWLAQPSTFLFDKETGAFAPQEQVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV7</accession>
    <name>V6DWV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4789" checksum="7603A266BAA9E82B" modified="2014-02-19" version="1">MAGVGVFLKYRHRLLVTTAKLIKILVVRASPRIDSSDQRLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV8</accession>
    <name>V6DWV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4097" checksum="AD3ADDC7A02476BC" modified="2014-02-19" version="1">MRCPRDWGFGGVRRTSDESALVANTGRKVGFALSISTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWV9</accession>
    <name>V6DWV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
            <ecNumber evidence="3">2.6.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_09429</name>
        <name evidence="3" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078179.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="34141at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="446" mass="48453" checksum="C182BBE1C339C4FC" modified="2014-02-19" version="1">MDRDTATPAVDDLPGERAREWVEYHHESAAPSTYVYEFVWDRTAPAEGPFCTDVDGNVLMDFTSHVAAAPLGYNNPLIMDRLEEFDLVDPLKIAGQDFYAAGGPTPDDGLPGSSGLMDRLTDLTAHYDMDTVFLSNSGAEAVENAIKIAYDESDGAKYAITFDGAFHGRTLGALSLNRSKAVYRRDFPEVSGVMDVPYCDDRTCSAETCSCGFFADGVSRLRRKLDPKRGNVHPDDVAYLILEPIQGEGGYRFPSEAFTDEIAALTDEHDITLIADEIQSGVGRTGEMWGSDHYAYEPDVIASAKGLRVGATVSRSDVFPEETGRLSSTWGAGDLIASAQGALTLDAIEEADLMDNAVTRGRQFKETMRDADLDPVEDVRGKGLMLAVEFDTKERRDAVVKNAFGRGLLTLACGHNVLRILPPLDVTEREIDLGADLLTDAIAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW1</accession>
    <name>V6DWW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">50S ribosomal protein L15P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl15p</name>
        <name evidence="6" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="5">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10786" checksum="148D28E7A837D4A5" modified="2014-02-19" version="1">MKVQKLDEDAALYAAEDLAEEDGDAYVFDARDVVEDGHEADVVKVLGGGQVRRELRVTADAFTAGAVELIEEAGGEATLSERAEDAADEPENTSDDENDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW4</accession>
    <name>V6DWW4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5808 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_12927</name>
        <name evidence="3" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078194.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122393at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043831">
        <property type="entry name" value="DUF5808"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19124">
        <property type="entry name" value="DUF5808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5808" evidence="2">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10555" checksum="299215353FACAA52" modified="2014-02-19" version="1">MADKQSSGEILGIPYNFERPSLGRLLSSYWQPDKGMLVEKPFGIGYTLNLANWRSWVVLAVAGGLYYQQQQSGGAAVSEEGASEDDDGPVEVIVDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW5</accession>
    <name>V6DWW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hmuk_3241</name>
        <name evidence="1" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="11146" checksum="F97CEAC1CC90F22A" modified="2014-02-19" version="1">MLLELLESPLDEVIERLRVDFDSSQLNQLSKHPAERWLSRSHIARLASAQCNYTVFPRFYIRGIFAFSPVGDGLFVDVDDVAAESQLKESLYNSIVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW6</accession>
    <name>V6DWW6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl6p</name>
        <name evidence="3" type="synonym">rpl6</name>
        <name evidence="5" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078227.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80629at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_A">
        <property type="entry name" value="Ribosomal_L6_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_L6_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019907">
        <property type="entry name" value="Ribosomal_L6P_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03653">
        <property type="entry name" value="uL6_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="4">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="4">
        <location>
            <begin position="92"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="19291" checksum="477A7D2D20BD998C" modified="2014-02-19" version="1">MNRVEIEIPDDVSAETDHLELTVEGPNGSVTRRLWYPDVDVSVEDGAVVITADNEDAKTNATVGTFESHVANMIHGVTEGWEYAMEVYYAHFPMQVTVEGDEVVIENFLGESAARRTPIRGDTEVQVDGETVTLTGSDKEAVGQTAADIEQLTKVTDKDTRVFQDGVYIVEKPTGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW7</accession>
    <name>V6DWW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_12877</name>
        <name evidence="3" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078198.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15948at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="120"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="557" mass="62765" checksum="928452482E04CC16" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW8</accession>
    <name>V6DWW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="4810" checksum="D56F379A7ACD727F" modified="2014-02-19" version="1">MDMSTISLLPGVTAPAAAVLGGVWLVHGGTVAIGAGFVLAALVAWAYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW9</accession>
    <name>V6DWW9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplX</name>
        <name evidence="2" type="synonym">rpl24</name>
        <name evidence="4" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Located at the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008584888.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107015at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_L24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_L26/L24P_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="PTHR11143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="13335" checksum="A0941A8DE8D6A4E6" modified="2014-02-19" version="1">MTKQPRKQRKRSETAPLHERQNQVRATLTADLREEYGQRNVRVNAGDTVEVLRGDAAGTEAEVVSVDLSAERITVEDVTVEKADGEEVPRPIPASNVRVTELDLEDERREARLQEDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX0</accession>
    <name>V6DWX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphodiesterase, MJ0936 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_05257</name>
        <name evidence="3" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9520" checksum="BE1D5757A5B40B80" modified="2014-02-19" version="1">MGEYDGIVLGHTHVQGVREAGGGFVCNPGSVGQPRDGDPRAGYAVLDTTTDGTDAVETRRVEYDIDRVAVAVREADLPELTAERLYEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX1</accession>
    <name>V6DWX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_15692</name>
        <name evidence="1" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077420.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113365at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8575" checksum="ECA3E8BACD2F4C16" modified="2014-02-19" version="1">MNRTGKYTVVEACNDHGAITLREHPRNGTLYVVEYDDPEVEAELSSLDPGSVVELDLRRAGRRGNAWCAESARAVDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX2</accession>
    <name>V6DWX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14272" checksum="54462C9A0155DAF4" modified="2014-02-19" version="1">MISLRQELRKIRTYARRYGGLGGADGRRHRRIRRGSTPLCSGGKPLCSGSFREYLSVSLRSGYAYVSGNRSLVTYRIQRQTGGTDVVYGIGHVDAGRARTSERTRARLASTPTLRMIQIPRQASGVAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX3</accession>
    <name>V6DWX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5309" checksum="4BBD66BBDD60AA94" modified="2014-02-19" version="1">MTADSYFNRPARSSISLHKRQVDPRGTFAEAVEICHRHSELVRLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX4</accession>
    <name>V6DWX4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpl23p</name>
        <name evidence="6" type="synonym">rpl23</name>
        <name evidence="8" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit. Contacts protein L29.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078239.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113971at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_L23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019985">
        <property type="entry name" value="Ribosomal_L23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03636">
        <property type="entry name" value="uL23_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9210" checksum="7A887299FA5BB3AE" modified="2014-02-19" version="1">MNSIIEHPIVTEQAMNEMDFNNKLLFLVDVDATKPEISSEVADRYDVGVVGVNTQVTPQGEKKAIVTLSEDDDATEIASRIGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX7</accession>
    <name>V6DWX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Insertion element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03893</name>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="15142" checksum="02EA42D85E1CD3DC" modified="2014-02-19" version="1">MFVLVDRGTERRYIVPAKSADESTIRLLLADRQQEPLTVYTDGFRAYDPLEEDESFDREYVVHGDGEYAADTVHVNTCESHASLARRWLSPHRGISKDRLTQYFRAFQLRRELYRKPGREALKHAVKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWX9</accession>
    <name>V6DWX9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="4">IGPS</shortName>
            <ecNumber evidence="4">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_07657</name>
        <name evidence="4" type="synonym">trpC</name>
        <name evidence="6" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_A">
        <property type="entry name" value="IGPS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="5">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="209" mass="22108" checksum="3B0F2037F22ACB5F" modified="2014-02-19" version="1">MIAEVKPTSPTTDGAREDDPVALAEGMVTGGAAALSVLTEPEHFGGSVDTLERVRDAVDVPVLRKDFVVDEDQLDAVESDVVLLIARFVGDDLPDLLAAARDRGFQVLVEVHDREELERALDAGATTVGVNNRDLAELVVDLGTFESVAPHVPDEVTLIAESGIGSPADVRRMRAAGADALLVGSAIMDGDVEANTRELTRAETTEHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY0</accession>
    <name>V6DWY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05055</name>
        <name evidence="2" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077406.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83850at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="189" mass="21287" checksum="2ECBFE01622BE765" modified="2014-02-19" version="1">MTGRVFRLHSTLELPLEDVEAYFDEDPDLPPEIDDIDITRRNNTLIIKALSDDESISKYTPTAQLKASVTETRVWEEEPPRAGGPQWMDDEEEEIPSELVEFACFKGDRETVLQNSALQYPMFLVLREIATLSEKGTLTAITEENDELEATRIVEGERRPASIEVVESPQGAGEGDGGVNWRDNEFISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY2</accession>
    <name>V6DWY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="8944" checksum="B5D1E7F47895991F" modified="2014-02-19" version="1">MGLGGIDDDTDTTNCGSNDATGLPPTATSTMTESRTDERERTARPAETSNSEPMAQPTTTGPVDAGDSNQQSRRRETRERGGGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY3</accession>
    <name>V6DWY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phospholipase/carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_05000</name>
        <name evidence="1" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="9635" checksum="6E88BFB0198061F5" modified="2014-02-19" version="1">MEDPDRYAWVVALHGYLPESHADLDPDGIEGKPVFVGAGAGDRVIPDERTNAAVERLEAVDAAVTHGSFPGGHGIGPQELEAVVEFVESQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY4</accession>
    <name>V6DWY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monovalent cation/H+ antiporter subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C473_16172</name>
        <name evidence="8" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077396.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128222at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007208">
        <property type="entry name" value="MrpF/PhaF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34702">
        <property type="entry name" value="PTHR34702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04066">
        <property type="entry name" value="MrpF_PhaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10371" checksum="8BE8B61715532F0D" modified="2014-02-19" version="1">MSLVDATLAAGYTLGDFLLVAAAGFAVLAVGMLYRAVVGPTMQDRVLAVNVLGTNTVVILAILGAALGEPTFLDIALVYALLNFLMAIAISKFTVEQGGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY5</accession>
    <name>V6DWY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_09990</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="349" mass="39226" checksum="B7E7D6E21E295299" modified="2014-02-19" version="1">MIPDKSHLPDGYADHLRSLTERLTSLRETLESDHTLTTDQRMFARRLMHLTSQPITEAERILPDPDCDDDSTDDSVLDSADDYANALAHVEEQLCWLIRSLRAALVDANYDEAPAEKFTTALEHATALRDILPTVPTESPVLATQADINPSEIDPHVGGRGDSDGRWLEYQLDRALNRWGYGAARRQHIFSLEVDVVARRRTKQQEPSDWIVAQCKDWTTDPITPRVLFRLCTVAFACRAMPVLCHTTELTPRAEKLARELEVRVLTLKDLERAELPAPHVAKPTTALNKWGPQYQAREDRGSFPLMFRGEPGKRFSYVPGFAPVGNGADYEPIEGDQDDDDTHPAAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY6</accession>
    <name>V6DWY6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6 9">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="1 6 9">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">pgk</name>
        <name evidence="10" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 9">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="1 6 9"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078211.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46017at2157"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6 7">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 7">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <begin position="358"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="407" mass="43866" checksum="B7E88B3717F009A3" modified="2014-02-19" version="1">MPTFDTIDDLPTDSRVLVRLDLNSPVEDGEPQDNRRFERHARTVRELAEAGHRVVLMAHQGRPGRDDFTSLSGHAAILADHVGRDVDFVADTYGDEALAAIDALGAGEILLLENTRMCDGELPEESPEEKAETEFVRTLAPHFDAYVNDAYSAAHRKHASLVGFPLALPAYAGRVMETEYEANTAIATREFDGPVTMVVGGTKATDVIGVMDALDEKVDRFLLGGVAGELFLRAAGHPVGHDVGGMDLFDEQWEANRELIESVLDERGDAIRLASDLAYEGFDGDRAEVAVDDIEEKTEGFLDVGSETVADYEPAIRESDAVFVKGALGVFEDERFADGTVGVLEAIAETDCFSVVGGGDTSRAIEMYGMSEADFSHVSIAGGAYIRALTGEPLPAVEVLEAAAKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY7</accession>
    <name>V6DWY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5626" checksum="1A07097E29FB585A" modified="2014-02-19" version="1">MSRVADRREATTNERAPGPRVARSTVRETSYASEVVEPIGTGGVRIDPNTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY8</accession>
    <name>V6DWY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xaa-pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_12766</name>
        <name evidence="3" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="198" mass="21486" checksum="3F5D0565E58E1220" modified="2014-02-19" version="1">MATRLPESAFEDRLAAVRDRLAATDADAATWVGATAIEYLTGFHHIQTERPVVLAVTDDRVEITVPRLEVERVSPNSRIDAVHDYFDYPGGEPVSVAVEMLNGLGVDAIAADADGPPGVMGYEGPAFSDSLDVETQSWVGRDALGEVRRRGRPDPRVGEVGEPRAPLPRRLLRAGGAPGDRLAARVDRRVPRHARHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWY9</accession>
    <name>V6DWY9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Polbeta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HQ_1903A</name>
        <name evidence="3" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077788.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="2">
        <location>
            <begin position="121"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="231" mass="25860" checksum="B56F35F0D3BBE8E3" modified="2014-02-19" version="1">MNRETNSQNSPGGTISLSIPPSDPALFKHKATSDILLFLTNHRFSDFSLRELATQIDHSHQSVRRAVNVLSANDLVVDSPESNQRLVQINRQRLSIPDDPILRISQSEYHQPVKAAVTELRENINDVVGIILYGSVARGEADRRSDIDLWVLTRSGRAESQREANAIARDLEETEFDGNRYAYDIDVEAVQAIPSYTKDIREIVVSGIPVYKTSDFETVENLLLEEGAADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX70</accession>
    <name>V6DX70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03091</name>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="9727" checksum="0D9D6EB1468EF1F3" modified="2014-02-19" version="1">MIVGATVVAALGAGPVAWLARDRIPASRREMYGRILVAISLPAFMLFVGVSLAFGIPFLSVTDAVVVGVVCGGAVALLAERTVVPERYRAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX71</accession>
    <name>V6DX71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10424</name>
        <name evidence="2" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077478.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107536at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14580" checksum="3DC5A1A2624564CB" modified="2014-02-19" version="1">MSSGGSSYGDIHRYEPARESTAAAIAIVLLTVIEVVFVALFTYGLMSAWASTEAGNMYVGALLALIFIDLAFILLLYRKEFLPDVMIVKKRRRKWEDLYVREEDKEGDGIDTGNLAETLKRAVYPYYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX72</accession>
    <name>V6DX72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PadR-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_06965</name>
        <name evidence="3" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077865.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116902at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="29"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12930" checksum="2D1C29112DEBCE21" modified="2014-02-19" version="1">MAKWFHSGRRRDLCALLYDHGELRAQSAKSRLESHYDERIDPGSFYGTLSALVESGYLDRRTEGIADVYTLTEAGETALLDHYAWLGERIDGGGKPEDDDRPEGGAERDEPNLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX73</accession>
    <name>V6DX73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="10080" checksum="DF00EE2C372CBA9D" modified="2014-02-19" version="1">MRCCAGRGSKGQPRDGQRRRQDRKERAERATEDRTERLSVSRLGLRWSSRRQQPCRAERLGLRERPCRSAIYKEPSAIGRFGQNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX74</accession>
    <name>V6DX74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_08380</name>
        <name evidence="3" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078323.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62109at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="152"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="26142" checksum="F7100189E8B82B8C" modified="2014-02-19" version="1">MSTEADFGERLEAQTVTYLDRIDDCVVLLPRVLDEYAADGPYRDTVDEIAAVESECDDLVRDLRTLITDAGPDDIGLLNTRINFNESALLDFYNELDVVANLTERIAQEVAMMRPDAGVDSFDDMREMADRIAEMVAVLGDVVEGFVRGLARADATETLTEGIEAIRELESECDGLRNDAIETAFADETIDQPLVYRELAILLDELANAVEDLTDRIVVIASKEPGIVTESASDADGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX75</accession>
    <name>V6DX75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_01422</name>
        <name evidence="1" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="10371" checksum="AAE287F341F9E300" modified="2014-02-19" version="1">MDRFTRRPPTAIGEHNRVSTRYFARRDDAEWTSKPLSDVRDGWHDTVECATALVQCYEDGMWIRVRDDCERHAPSRLRGVCSNESTAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX76</accession>
    <name>V6DX76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077868.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="142843at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="6976" checksum="2E51DB1D83E465E3" modified="2014-02-19" version="1">MIDDVVELVFDVLLGFVPNVVLGAIALVVGLVTTAVGIATLSDPGMMGEALTVVGLSVVAGVLILWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX77</accession>
    <name>V6DX77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="11810" checksum="67795DFEEB641E55" modified="2014-02-19" version="1">MRTARLTGTGSLPWELPHAHAAQFRFGPAGRGVAISPPPARGTQPRSRAASRPSASVRPARKSMLKTPPEQPRHMILEAAVTEPLPIAGTAAAVLLASLALVVVWVAYLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX78</accession>
    <name>V6DX78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_01906</name>
        <name evidence="6" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078301.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93366at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="28"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="16670" checksum="8384C9E9C46E8C4D" modified="2014-02-19" version="1">MDESRRIAGVDEVPEESTLLVTLRPTDPDAVGEGEGDLGEGEDGDPEVEAILTRAAGEVRAFRNYCQHWTDVRLDKDDGAFVRNGEVFCQKHGATFEADGGYCNFGPCEGAVLESVSVTVDGDDVFLDDDAYEFVRLGPSAGKGDGSGSRIDFTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX79</accession>
    <name>V6DX79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_03131</name>
        <name evidence="8" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.20" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077486.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="377" mass="41399" checksum="ACA4E02A94049933" modified="2014-02-19" version="1">MARVTLDTLRKEFDRGTIVAVDDLDLEIDDGEFVTVVGPSGCGKTTTLRMVAGLEEPTSGTVSFDDEDVTEVHAKERPVAMVFQNYALYPHKTVRENMAFGLKMSTEMTKEQRHERVREMAEMMGIEDLLDDKPDELSGGQKQRVALGRAIAREPEVFLFDEPLSNLDAKLRTEMRAEIQKLQKEFGVTAMYVTHDQEEAMTMGDRLAILNDGKLQQVGAPTEVYQKPVNKFVAGFIGSPSMNFLDVDVETDGTTATIRDESSGLALTLSSEYVAGHDLESGPYTLGIRPENIGIVEDPTGEETLTATVEVVEPIGSDNYVHLSVNDDFLARAPPDVQPETGDEVGVVFDEADLHLFDAETGEDVFLTDEEIAAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX81</accession>
    <name>V6DX81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C463_02918</name>
        <name evidence="7" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077878.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="272" mass="28188" checksum="F5E5D414C3CD8927" modified="2014-02-19" version="1">MSLPAVARKDLRETVQSRGMIALIALFSLLVSVLAFIVRPTGQNEQFATEALLSFFVGPVLVTYLVPLVGVVVGYGAVSGERESGSLKLLLSLPHSRADVVFGKVIGRGAALALAVFAGFLLPAAVLIVVPVTFNAGAFLGYTVFAAALGVVFVSISVGCSAASSTQLRALIGSIGVYVLFVLLWSVLTGRLVGAVPGSVINALPLSATQIRVFLQVSNPTSAVEVLSNAFLGGQLFSGQQANRQLSAAAMLVFWTVAPPLAGLLKFDADDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX84</accession>
    <name>V6DX84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_10474</name>
        <name evidence="1" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5624" checksum="401B9D80F0658955" modified="2014-02-19" version="1">MLASLDGVAFDAPDSPWIESFDPTRFDGDEEFGIVEGMSLSERTEGETGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX85</accession>
    <name>V6DX85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6715" checksum="F2433D3EF26E1323" modified="2014-02-19" version="1">MKVKFREGARVKMAHHAMYPLPRKDLILPPWVLNPLRPWHVEESERVNRTVVNEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX86</accession>
    <name>V6DX86_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Taxis protein CheF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06863</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in taxis signal transduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078309.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43199at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007381">
        <property type="entry name" value="CheF1/F2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42201">
        <property type="entry name" value="PTHR42201"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04283">
        <property type="entry name" value="CheF-arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026802">
        <property type="entry name" value="UCP026802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR026802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="289" mass="31647" checksum="9DC26CCBD959FB23" modified="2014-02-19" version="1">MEESVVADFVGRVHAASLQTDEPATGRVLLSQRRLVLATDDGKETVPLSQVFDVVVGSVPGDLRSFFNDSVTVAYERDGTRRSALVEGESEDMDRFVRLLFTVLLRNVTVTVRHPAKVGGRVTDATDHRASVTVSPGEIRFDDCPEPFTVDLSSVIDYERTDRTLGGTKRPALVFRHVDDDRTVTSITTVPNERALNILGRYIKIEYDEAMEDLDSFDPTEEQLEILVSIYSAGGEANISDVVTGDVTQTSMILDTLREADLVADGESGAALTRKGQMIVSSYLESVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX87</accession>
    <name>V6DX87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01997</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078339.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111287at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="37"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="131" mass="14346" checksum="E9C2D4F3F062E50F" modified="2014-02-19" version="1">MSSTDRLQRYVADECGSCTDEELSKRLAELEALNDSVGGSDLETDVDLLSALANETRYKIVRMLHAADDDELCVCELSPLLDVSDSAISHALSKLTDAGLVTRRKEGKWRMYRATPRANAVLVALDGSRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX88</accession>
    <name>V6DX88_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03181</name>
        <name evidence="2" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077490.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114465at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="11146" checksum="02819536D7D5C8AE" modified="2014-02-19" version="1">MDDTDIEVNARVTEDRTVIDVTGTRDVAVVVRSGGGERIYLPPEGFDDPVSGSPYTSPYQGSGAGGEESPYGGGTGSTRGVMDTADGFRVTHPEPVTEFDVYRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX89</accession>
    <name>V6DX89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transporters inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_03121</name>
        <name evidence="6" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077485.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42276at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="90"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="36060" checksum="B8D154C14B6EF78B" modified="2014-02-19" version="1">MASSQPGTAASGLSRLRSVLPFASRDWGLLLVAPGVLLFSSFMLYPIFYLFYISLTNATFAGSVIGGGAELIGLANYVQLIYDSQFWTSMTTTWLFVAVSLVAKVFLAVGIALLLNHVRVAGKRYMRAAVIVPLGFPGIFTITVWRGMFSDARYGVFNTILGRYNEFMSSLSAPQALLFDVPIGFLSGRWEAFFAYVTTEVWLAYPFMVIIIVSALQDVPRSLHEAAMVDGAGALQRFRTVTLPAIKGPVLFASILTAATSFQQFLIPWVFNQGGPSRQNELIIVYGYREAITFNQFGLSAAILIVGIAFVGLFMLVAVRYGGLAEGVGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX90</accession>
    <name>V6DX90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenic resistance protein ArsA</fullName>
            <ecNumber evidence="2">3.6.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01987</name>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="169"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="285" mass="31161" checksum="8FBD4CC7C5A0D85D" modified="2014-02-19" version="1">MEPSGEETEFVFFSGKGGVGKSTVSCATATWLADNDYETLLVTTDPAPNLSDIFGQSIGHEVTAIDGIENLSAIEIDPDTAAEEYRQETIEPMRELLGEEEIRTVEEQLNSPCVEEIAAFDNFVDFMDSPEYDVVVFDTAPTGHTIRLMELPSDWNAELEKGGSTCIGPAASMEERKQDYERAIDTLQDGERTAFAFVGKPEDSSIDEIERSAGDLAELGIESQLLILNGYLPESVCEDPFFEGKRADEQAVIERAREEFDADATATYPLQPGEIAVVGGKAHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX91</accession>
    <name>V6DX91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_10911</name>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078312.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121557at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8733" checksum="89C5097D354620AC" modified="2014-02-19" version="1">MKVDATDLKTNETDDRGRVYLGTEYANKRVTVAVVEVESDRPDDDELAAAYRDASESAAALTEEWSEMSDEAWESLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX92</accession>
    <name>V6DX92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="12013" checksum="253BD20D608742DA" modified="2014-02-19" version="1">MFSGNRLVQTTYPSFRVVAVLLLELHSDSRACTICGLDHRRSETAGAQEARKAIATSRMTKTRIGRRNQTTSHQLDPVESSPEGCREPGGESPIAPPGSYIYNAFEYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX93</accession>
    <name>V6DX93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_06495</name>
        <name evidence="8" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.20" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077882.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="372" mass="40796" checksum="92DCA5A02CBC8CE3" modified="2014-02-19" version="1">MGTLELDGVTKVFPDGDGEIVAVDDVDIEMRDGEFLVVVGPSGCGKSTTLRMVAGLETISSGDIRLAGKIINDVKPQHRDIAMVFQSYALYPHMTVRENMAFGLEESTDLSDGEIDERVTDATETMGIAELLDRKPSDLSGGQRQRVALGRAIVRDPEVFLMDEPLSNLDAKLRSEMRTELQRLQDDLDVTTMYVTHDQTEAMTMGDRIAILDAGELQQVATPLECYHEPANQFVAGFIGDPSMNFFDVQRDGETLVSPLFDYPLSESTLDDIGDVTDLTLGVRPEDISLAGDAEGEHTFSTVVDVVEPMGDENTVYLRFEDAPEDQTFIATVDGLQQVAAGDEITIEIPEETIHLFDGNSGEAVHNREIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX94</accession>
    <name>V6DX94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_03176</name>
        <name evidence="1" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5769" checksum="B9D8D6AD13041EA7" modified="2014-02-19" version="1">MVADDIADALVGRAYRVRGNLSVDDYGANLDADEFELADDDPADAARAALAEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX99</accession>
    <name>V6DX99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein synthesis factor GTP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_07839</name>
        <name evidence="6" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK39995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039263">
        <property type="entry name" value="GTPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="PTHR43721:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="148"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="569" mass="61114" checksum="04D54C2CFF6A4561" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0F2</accession>
    <name>V6E0F2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_13802</name>
        <name evidence="4" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078425.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000030.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89741at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="3">
        <location>
            <begin position="62"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="17383" checksum="2B98D426E3A3DCF4" modified="2014-02-19" version="1">MDRTDIAEMDPLPADATEFVERKLEDEHGYLSWLNTSVETIERGRVVLSIPFDDKLTNADGQTIHGGVAATLIDTAGGVAQRTTFENPLGGGVATVNLDANYLRPATGDLRAEAEVVRAGGSIGVSEMTVTTAVDGAGGTDENDGEENRSEVVVGQGSFRLFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0F4</accession>
    <name>V6E0F4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="178" mass="19460" checksum="26B5A6F7D44FA006" modified="2014-02-19" version="1">MFDEVLGGTVGDTSGTGNALSLPAGVREIPPLVFALFEDGLVVRELDRLALFDELDLEVLHLVFGDVAGTGADGAALFEFALLAVGTGRDRARAATAAADRAVTGFGELRLRNRGRAVFEHFLGDVGRGFPPRSLHGGDEEDEQRRDRRERDRGQAHDPRDRHDRQWAKHTRGYGEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0F6</accession>
    <name>V6E0F6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">GMP synthase [glutamine-hydrolyzing] subunit B</fullName>
            <ecNumber evidence="5 12">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">GMP synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">guaAB</name>
        <name evidence="15" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="5 12"/>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078435.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000031.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31932at2157"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00345">
        <property type="entry name" value="GMP_synthase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026598">
        <property type="entry name" value="GMP_synthase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12 13" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12 13" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="14">
        <location>
            <begin position="2"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="29"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CDK41088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="305" mass="33776" checksum="38B149C3FD4DE5DB" modified="2014-02-19" version="1">MVETEEFIAEAKAEIREAIGDANAVIALSGGVDSSVAATLAYEAVGDQLTPVYVDTGLMRKGETEEIRETFSFMESLRVIEAQERFFDRLDGVTDPEEKRHVIGEGFIDEFETVARDVGADYLVQGTIYPDRIESEGNIKSHHNVGGLPDVVDFEGIVEPVRDLYKDEVREVARALGLEEVISERMPFPGPGLAVRIVGEVTPEKAEVAREATHVVEEELEEYDPWQAFAAVLGKATGVKGDNRVHGWVVAVRSVESRDGMTARAQELDWSTLQRIQSRITGENENVARVVYDVTHKPPATIEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0F7</accession>
    <name>V6E0F7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L10e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpl10e</name>
        <name evidence="6" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078419.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000029.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82104at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00448">
        <property type="entry name" value="Ribosomal_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_L10e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022981">
        <property type="entry name" value="Ribosomal_L10e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018255">
        <property type="entry name" value="Ribosomal_L10e_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="PTHR11726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01257">
        <property type="entry name" value="RIBOSOMAL_L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="5">
        <location>
            <begin position="14"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="176" mass="19725" checksum="9688DF461665B363" modified="2014-02-19" version="1">MSDKPASMYRTIDKPSYTRREYITGIPGSKIAQHNMGDLTAEPDDYPVQISLRVEEELQVRHGSLESARLSANRHLIKELGEGNYKMTLRKFPHQVIRENKQATGAGADRVSDGMRQAFGKPVGTAARLNKDDVVFTAYCDVEQASVVKEAFRRAYNKLSPPCRITVDRGEKLLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0G1</accession>
    <name>V6E0G1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4716" checksum="D7C56E83E54F844D" modified="2014-02-19" version="1">MVVALLLPAWFANRSRRSQRDLSATEQYRTERTRVTPEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0G6</accession>
    <name>V6E0G6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C467_11050</name>
        <name evidence="12" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078432.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000031.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51079at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="324"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK41085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="399" mass="42591" checksum="B1312292E9FA9451" modified="2014-02-19" version="1">MRGIKIGSAFGIPIRLNWTFLIVLPLFAYLIGQQVGSIVDVMNETAGLGIDAAVLASGPAPWLLGLAAAVGLFVGVLLHEFGHSLVAMRYGYEIESITLWLLGGLASFTEFPEDWKHEFWIAIAGPLVSVAVGIACYGVVFALPAGAGASVGVNAALFVFGYLALLNVVLAVFNMLPAFPMDGGRVLRALLARNQPHAQATQRAASVGKIFAFLMGIIGLLTFQLLLIVLAFFVYVAASGEAQQTTLRAAFEDVTVGDVMTRREDLHTVTEDTSVADLMSRMFEERHTGYPVLDGDELVGMVTLEDARSVREVERDAYHVDDVMATDLVAAAPEADALTALQTMQESGVGRLPVVDADGDLVGLISRSDLMTAFNIIQTGGTPRVIGGRRRVDDEPGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0G9</accession>
    <name>V6E0G9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000032">
        <property type="protein sequence ID" value="CDK41093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6327" checksum="BA2EC6E64B540E68" modified="2014-02-19" version="1">MRCGAGIEGAAGRRTQATVGPQRGSDSDRVRTAPSVRPPPGWGFGGLRVDNLFINNYPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0H1</accession>
    <name>V6E0H1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaredoxin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_11018</name>
        <name evidence="1" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078437.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000031.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114503at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="11068" checksum="148D205B42A8F8DE" modified="2014-02-19" version="1">MSESTSTDGGEGDADDGADATVPVTLYTREDCSLCVVARETIESVAADLDGVAVDLDEVDVDTDPELAEEYGERVPYVLVDGHPAFKYEVDERDLRLKLLAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0I0</accession>
    <name>V6E0I0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_06555</name>
        <name evidence="4" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000032">
        <property type="protein sequence ID" value="CDK41095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078441.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000032.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="86"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="150"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="350" mass="37702" checksum="177F1EB77BC06648" modified="2014-02-19" version="1">MKSAPESTPIDHAESIVNALGDGAYVLDADRNRVFVNDRLREVTGFDEAVLHGVHPERLVEAGYWTEETGDRYRAVIDRVLLGESDDERVQLTTTLGDGSEVTTETRLTPIERDGEIVGAVGVIRDVTDRVERERELERLNERLERLAGFLSHDLRNPLSVARGYVDLARETGSTERLAAAEEALDRIESMIGEALVMARDPAEIDTEDAAVDLDDLAADCLESGDFGDRPADAEIVVEDSGPVTGDPTLLRRAVGNLIGNAFDHASDASTVRIGVDDRGLYVADDGPGLPDDERERDELTEFGVSRGGGTGIGLAIVERVAAAHGWTLEIGESADDGFRATLVGAEPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0I4</accession>
    <name>V6E0I4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoserine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_05622</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000033">
        <property type="protein sequence ID" value="CDK41098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="292" mass="34623" checksum="3380D56D0D0D5930" modified="2014-02-19" version="1">MDEADNVDLSEDDLENGSKGQLIKRAGQLRDRRNELNQMASERASKRDDLNAKTREKVDEAQEHRENRDELNEQVQEHKDKRNELNAEANELFDEVEELKQDLELGSGKSIEELEEEIEDLEFRQQTEVLDAEDERELIEKIDDKREKLAEKKEKVDDTSELDDLVEEAEEVRSEASQHHQKVTELADKAQEHHNQMIEAYREADDIRDEADEMHELFVEAQEAADRHHEDFVRVQKRLRELDKKEEEERQDERAEKREEEKEEAEEIYQKFKEGETLDTEDLMKLQKTGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0I8</accession>
    <name>V6E0I8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15859</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000033">
        <property type="protein sequence ID" value="CDK41103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078452.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000033.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87487at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="21257" checksum="6360D2F8BF86FAA0" modified="2014-02-19" version="1">MDALAQAGLLSPDTLPLLLLTAGLLLSMAEALAPGANFIVVGIALIGAGLGGLLLTSLGVAGALLTLFMALLTLAFGAAAFYGYHEFDLYGGKGQQQTSDSDSLKGKTGTVTERVTPTGGEVKLAGGGFNPHYSARSMDGEIDEGEEVMVVDPGGGNVVTVESMGYVEDDIDRELAADRARKAAASEADVESTEESEADAETEVERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSJ1</accession>
    <name>V6DSJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12479</name>
        <name evidence="2" type="ORF">BN903_200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076327.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="14771" checksum="05E32E177D434258" modified="2014-02-19" version="1">MIERVLVAMDGSDLAEQALRYALDAHDDAEITVIHVLGGASPMMGEATGLALSDDDDDGVREAAEPVFKRAQEIAAEHDKTVETLIAVGRPARSIIDHAEGFDTVVLGTHNSSLADRLLVGNVAKTVFQKSPVPVTVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSJ2</accession>
    <name>V6DSJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HSB1_39190</name>
        <name evidence="1" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076853.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32950at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="345" mass="39566" checksum="E70EFD0E875E0B04" modified="2014-02-19" version="1">MTRRSQRHRTTTLPFSYRNKGMDFDLDSFTVDDGDRTALELNPSQTEIDLASAVSSPDSGDESDWSTITLHGELRLPKETVQAVFPEDERAQPPAKLYVAIRCHETIYRDRIVVSETPTTPGEYNVELEIPKDTVRGTVELRPYLVRTEAHPGEEPNDYADQKNFRVASGTLYYVVVDRDEEEERAAIDGERVRFSQNAHLPDGNKLYYLDFRNEGRPKLWINSDHPRIAEVLQNRGSVGAEARMRDVILDQVSYGVWVQLLVRAGSAVDAEGEVEHEWQEMVLQTFARNLYDTSDISEATHRLRDDLSDPQTLPHVIQRIDSELQEYIDPREQLIHLMEEGLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSJ3</accession>
    <name>V6DSJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LtrC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HalDL1DRAFT_3282</name>
        <name evidence="2" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076870.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013610">
        <property type="entry name" value="ArdC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08401">
        <property type="entry name" value="ArdcN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArdcN" evidence="1">
        <location>
            <begin position="27"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="35093" checksum="96DB34C75B0126A4" modified="2014-02-19" version="1">MATTSDSSVSFEETDTRDNEMNSAIEQWIDELVAGVGDAQASEEFQEWLDVQSRFHDYSYRNTLLIKQQCPKATRVAGYRTWQEEFDRHVQEGESAIWIWAPIITKQCPECENSPGYHKDSDCNYDETPPEEWSEGLVGFKPAPVFDVSQTEGEPLPDLGTEATGDAGDLVTRLTDAADEIGVTVRIVPANEWTHGEAKGICEQLSLIDVQPRVEVRDRENEADLARTLVHEYAHTLLHFDVDDDTERAKREVEAEAVAYVVGRYCGLDTSGSAFYLATWESDDPEVVRERLGRISRTAEELIDVLEEPPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSJ4</accession>
    <name>V6DSJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NJ7G_4304</name>
        <name evidence="2" type="ORF">BN903_148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076951.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86851at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="131" mass="15323" checksum="E93338597AE0DFE2" modified="2014-02-19" version="1">MSLEVLNRHSEALFEFLWCPVCGHEIFTHIPFEGVFCKNCNTEVVLRESRETRGYEEAILACFDTAPTWNLHVDEKLRRDFPDGSARVKVFGAPDDYEVDWWSPEPDEYWQPVERGEFDDIEEPDDVSHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSJ7</accession>
    <name>V6DSJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_03235</name>
        <name evidence="1" type="ORF">BN903_205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="16237" checksum="999E21589F471ABC" modified="2014-02-19" version="1">MTEAADRIFVNGEVHTLADPEDGGDAVREAVAVRDGAIVRTGRTXXXXXXXVAGLQPPDRVAAAHDDHAVRLLFDQQRGRVRERVRLADAEKLAVHHVTDRGVCSHTSRIRSDRLKAAPDTVIPVPFVRLRFVPTLNGARPSESCPSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSJ8</accession>
    <name>V6DSJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076875.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="143110at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11356" checksum="D202B2CE88A5272D" modified="2014-02-19" version="1">MALLTPGSENVLVGGVLLLVGYLIKYRRWTWLISEATSLVAADDETAPVIASLIGNISVVIGAILLIIGSLQALRVVTNLPDWVFLGILAVATILVAPQLSYNLQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL1</accession>
    <name>V6DSL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="10387" checksum="00E7232CD88B721C" modified="2014-02-19" version="1">MTDEDAVTQEIATAYDVDEITVDSETFQKVVATTYYDGQLEYESVTQLVGTETAQRLCLLNADLKNEPLDLAAPDDVDVYDGDATTVETATDGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL2</accession>
    <name>V6DSL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HSB1_24670</name>
        <name evidence="2" type="ORF">BN903_150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076885.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130442at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6565" checksum="CA5C3893CFBE520D" modified="2014-02-19" version="1">MEFDFARSVGPLVVIVAIATAALTAVMTPSTVFMMVLPSMIGFSIIAFFLGMKHGEFQARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL3</accession>
    <name>V6DSL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_01684</name>
        <name evidence="1" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5868" checksum="9C2190DE9E321CF9" modified="2014-02-19" version="1">MVSKQFIQQIVRLEPSSKTLYECRQCGYSVEKDVEECPQCAAHEIAAYDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL4</accession>
    <name>V6DSL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C437_14999</name>
        <name evidence="1" type="ORF">BN903_167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076897.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113503at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="10737" checksum="C5E23DE57BCD4E55" modified="2014-02-19" version="1">MSDPDRYDETTDDHERFEVELLAQDRDAQSPSTADLDDETAHQMVRELLDAGTVTPVVDQRILIHEPSGTAFKSIQQLAVFHEGWTAAHDADEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL5</accession>
    <name>V6DSL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC transporter ATP-binding protein</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C471_00060</name>
        <name evidence="7" type="ORF">BN903_220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076339.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55756at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="247" mass="27125" checksum="97514EF1FAB8E687" modified="2014-02-19" version="1">MSLLELEDVHAHYGPSHILRGVSISIDEGEVVTLLGRNGAGKTTTVRSIAGTEPPQIRSGAIRFDGTDITDWPADDIAMGGIGVVPEGRRLFTELTVEENLELSTITRSWWNTIRRRGLGGGESTMEIGELYDLFPRLEERREQQAGTLSGGEQQMLSIARTLRLPDLDLLLLDEPTEGLAPQIVTAVGDAVEEIADRGLTVLLIEQNVREALRIADRGHVLDQGDIVYQGTTEDLENEDLDEYLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL7</accession>
    <name>V6DSL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C488_20047</name>
        <name evidence="2" type="ORF">BN903_134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076874.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="22687at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="385" mass="43516" checksum="442D28C537332AE3" modified="2014-02-19" version="1">MKDPETTTVFAGLDGRTDSKLPEWYAERHGGPEPVSFSKAVRNLPQAIDTAVAYRNPFTDEWVKTNRFNALVEPSRLQAEANDNQEIDSLFHIPTDSYAIINPVDVYGPLEEVLREETIDGTPLGDVMFGEIRRYRGGGEVHMDIMFDGLEVRLPGRSDPITMGVTSGYDFFGEHAVYVEGFAQDGYCSNTMRSLTDKEVIKHVGDVRNFRTWWEELLAQVELVADDLFEFIRDAQDIELDFSELPFTVTEFYTLLGFPDYLAERAAGDAEANAMSPFEIDMWTLHSGATYALTHFFQGKEGASLDQYVRIANDILFNPEGTIERVEQAYEEQLEADSDDGSQASLAGERALASIERVSDDLQEKVDQFEEREDTLRERFQDAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSL8</accession>
    <name>V6DSL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_00162</name>
        <name evidence="1" type="ORF">BN903_155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076889.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89800at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13936" checksum="A61E72CAD60CD883" modified="2014-02-19" version="1">MATLQAATTSTGAIVSNPQAVRELCESHCFGTLDWEVTEDGELTIWGHDDFEVYEARENGLPDYEGGIVTHEFLQELAGHLEGNEELDIQTAGFTKCRFPVLAKRYVVRDGEVLHADLSSPNPIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSM1</accession>
    <name>V6DSM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C489_19061</name>
        <name evidence="2" type="ORF">BN903_139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076877.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017259">
        <property type="entry name" value="UCP037672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12650">
        <property type="entry name" value="DUF3784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11407" checksum="705955F8145B5E60" modified="2014-02-19" version="1">MLDGGSIAIEWIASGAFVTLLGVLIKFAGWTWLLAGYSKSTSKVSDDIVQDMAGNTILRVGIATFVFGILASVIDLPSYLALVITAVIFLAVLRLIYRLNTQPSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSM4</accession>
    <name>V6DSM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_15054</name>
        <name evidence="2" type="ORF">BN903_177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10373" checksum="0B4AF8C8A693D70C" modified="2014-02-19" version="1">MAQASPRNNRPEADSDERSSVSVEAWLEVVSKELDPTECQGLVELGIYSIHDHSSARTITLPKDAETFHDAAAVKQFYFEGEDCPLLIVVPLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSM6</accession>
    <name>V6DSM6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C485_00430</name>
        <name evidence="2" type="ORF">BN903_165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076896.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73984at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="20965" checksum="A8ED49CD47E9F650" modified="2014-02-19" version="1">MSRTSHRADGDIVRDFLSVADLLAEPQLAQLYAYLARQDAATVQDVMDDLALAQGTAYSYVNRLVDAGVVDVTDDDQPRKYAARAIDLTVTTAAGDREYTITPALIDAVGRRETDADIDTYIDRHGVAGLATALTYAVARERGEVTHRLMADDLDISPLAAELILQALRPVVHEHYDIGEDVRHDTEDGANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSM7</accession>
    <name>V6DSM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5586" checksum="CBFB4E830F245116" modified="2014-02-19" version="1">MDRSITAAVKSDIIAPSAIVILVPSSDSTKHNDRMIAERTSELLTDTIVACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSM8</accession>
    <name>V6DSM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5449" checksum="9B4538D7F2C7F987" modified="2014-02-19" version="1">MGRLTVSPRPPIRGLTGRYCSVLDLVYGGSVYISQMSAAIGRAVRIELHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR0</accession>
    <name>V6DWR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6541" checksum="02310B4544B208D5" modified="2014-02-19" version="1">MIAAFLAGSTGVVIQSIIGRQEAILAQGLIFAISFLVGFGLVYGPSFIRAYTSSSDNRQQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR1</accession>
    <name>V6DWR1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pheS</name>
        <name evidence="9" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="258" mass="29561" checksum="87F832EEFFE54AF7" modified="2014-02-19" version="1">MKDVLVGMGFQEMEGPHADADFWINDCLFMPQDHPARTHWDRFALDVDPMESIPDELIRRVESAHRDGWGEDGDGYHSPWSEEFAREVALRGHTTSLSMRYLSGIAGAELEPPQRYFSVEKVYRNDTLDPTHLLEFFQIEGWVMAEDLSVRDLMGTFEEFYRQFGITDIRFKPHYNPYTEPSFELFGEHPETGEEIEIGNSGVFREEVTGPLGVDCDVMAWGLALERLAMLTTGAEDIRDLHGTLADIDFLRNAEVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR2</accession>
    <name>V6DWR2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylglycinamide formyltransferase 1</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purN</name>
        <name evidence="5" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077344.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37310at2157"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="4">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="534" mass="57492" checksum="A6D9585C4CAE3AE8" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR3</accession>
    <name>V6DWR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5377" checksum="BB96290C765729ED" modified="2014-02-19" version="1">MSRSGHRSEAMRASTTARASTPTRRSVPETRLLPELRVYPGHDRLIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR4</accession>
    <name>V6DWR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13642</name>
        <name evidence="2" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078170.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="16828" checksum="F17085C97D84564D" modified="2014-02-19" version="1">MFDTIVVATDGSDSVQRAVSVAVDVAARFDAEVHAVYVVDASEVESSPDTVRDDLREALDDQGRDALDRVSDAASDRDDDLDVTIEVREGRPASEIDAYARDVDADLVAMGTRGRHGENRFLIGSVAERVVRTCPIPVLTVRQLTEEDPRRTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR5</accession>
    <name>V6DWR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="19258" checksum="96ABFD317CFC70AB" modified="2014-02-19" version="1">MAPDLDRLPLGVRRAGGVDDVHHHVRVRQFVEELVAEALPLVCARDEPGHVEQFDRDVPFPVAAVLRAAALLAVETRAARPHVGHPAVGVDGRERVVRDVDVGLRGGGVEGGLAGVRLARERDRDHAGASRRREKRLSVGRGEATDGGHCGSASGGRGRARLEEAAGDAPRNQQRLAQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR6</accession>
    <name>V6DWR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="9597" checksum="167F62FB2BA6B4AA" modified="2014-02-19" version="1">MFAKRYDNFLSCTERPGSQNSHSDHGRVATPATPFIRAHRTHRRHGYRSHRRRRPRPARGVAGAVRVLRARDRRADARARRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR7</accession>
    <name>V6DWR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoesterase, icc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_02218</name>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="168" mass="17525" checksum="4EE7C26C1F3F4D88" modified="2014-02-19" version="1">MEALREACSDRGADLELVAGNHDTALADAWGGTVREAYVVEEAAAAGLESRTSAGEPETRTAVICHGHEPPSVTADRYVIGHVHPTIEIDGDRRPCFLRGAGTYRGADVLLLPAFTRLAAGVPVNDAATGGLNSPLVDDAAALAPVVYDPDGGEPLRFPPLGAFDRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR8</accession>
    <name>V6DWR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11085</name>
        <name evidence="2" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077749.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114315at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10545" checksum="B9CBB54F3C293D2F" modified="2014-02-19" version="1">MDRISAIRNVEDALREFENGEADLAATERRVAAVLRTYATEFDGDDDVYRAVGDSPVDGTVVVAPSEPAARERVLAASGISEDPDDGDQPDFDVERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWR9</accession>
    <name>V6DWR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8717" checksum="99AE621B59E72A2C" modified="2014-02-19" version="1">MCATVSSSSPPPPPPRQPASPTVAVPPAAARKDRRDAVRVDSYILTETGPRGTPSRHQQLKRIPMTPSDSQKLIWGPLSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT0</accession>
    <name>V6DWT0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="6590" checksum="8D7BCBE01A5B7BC5" modified="2014-02-19" version="1">MVGGLDGREAVVALEQRLRGPGRVLVGDVLREESSSPAGGASPGSAVGSAPCSAARSTGSYSDTRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT1</accession>
    <name>V6DWT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Hlac_0987</name>
        <name evidence="8" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="28704" checksum="34A22DD43846A4DD" modified="2014-02-19" version="1">MITVQVLADLGIDQGTLTGIVVVLVAASLASRVVGYALNAVAERSPDRRISIKMLIPIARFLIYAAAAFLVLGPLLRLSTAQLLAVSGLLGAALGFGLKDLFAGMIGGLVLITERPYQVGDKVAIDGDYGEVTNIGLRSTTLVTPDDSAVMVPNATLFTANVSNANDGRPEMMVVVELAVTASADVDRASEIVEEAMMTSKYVYTDDDHPLTVLVEDESYYRTIRGKAYVADLRDEFAFASDVTERSMAAFASEGIDMPEAPVNVSHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT2</accession>
    <name>V6DWT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_01689</name>
        <name evidence="2" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077765.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112736at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12863" checksum="809FE614E6CDC47A" modified="2014-02-19" version="1">MEQPSPPTSLPKYLAEGLPKQDTETLQEIHSYIEALIEYRDRSVDTDELPETAEPVEEPDNSENGTVVKEKVTCGDDSCKCASGKPADMHGPYLYRYYRENGTMKSEYVGKPGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT3</accession>
    <name>V6DWT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_07467</name>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7150" checksum="8DE856DCC5718E0D" modified="2014-02-19" version="1">MWLTVERWNRAAVSLYKKIGFETSDAESFELEMGLRLNPEVETGESRTDGEIEEPEGDGGDAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT4</accession>
    <name>V6DWT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6605" checksum="90C968EA769EF23D" modified="2014-02-19" version="1">MVNPACRDNIITGLKVRIKFCQLRRALRRRLETTRSITKYPGRSAWSSAGRRADSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT5</accession>
    <name>V6DWT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8378" checksum="40975BDC853A225E" modified="2014-02-19" version="1">MKHLLLFEIAVHGRVLVVDQQLIWDLVRCEDHIRPTASSRIGLLPARNVATPRASATSPFQQEYVQRIAFQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT6</accession>
    <name>V6DWT6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">flpA</name>
        <name evidence="6" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077366.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58340at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="74"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="90"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="115"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="212" mass="23133" checksum="36AED64068682FEB" modified="2014-02-19" version="1">MSEPTLPNGVERQEIDGERRLATRGEPVYGEPTADGWRAWDPERSKLGGMLELGLETGLAGGETVLYLGAASGTTVSHVADFAGPTYAVEFAPRPARDLLDAAEPRDRLFPLLKDARKPETYAHVVESDVDAVVQDVATRGQAEVAVRNARFLADDGRLLLAIKARSEDVTAAPADVFDGALDRLREAYEILETRRLDRYHEDHLGVVATPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT7</accession>
    <name>V6DWT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein</fullName>
            <ecNumber evidence="7">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C476_17362</name>
        <name evidence="7" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077769.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67630at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="24605" checksum="F420D78488759390" modified="2014-02-19" version="1">MSVIQLDGVVKRYDTGAEIIEALKDVDFHADRGEMVVVTGPSGSGKSTMLNMIGLLDTPTEGEIYLDGRTVTDFDEDERTEERRSQLGFVFQNFHLLPMLTAEENVELPSMWDTDVDRRERAVDLLERVGLGDRLTHTPDELSGGQQQRVAIARSLINEPDILLADEPTGNLDQDTGKTVLDEITRLKREENIAVVSITHDEQLVEYADRVVRIVDGVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT8</accession>
    <name>V6DWT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="10257" checksum="0CF3DAAC87303A18" modified="2014-02-19" version="1">MSEDRSLDNFAPDADGETGDAGTDGAVDTEPDGAVDDSTDAESDAAADASDDVDPATATSTWHAXXXXXXXXGFSTGGSPTTAAGRRPPIGTSKPPTSSYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWT9</accession>
    <name>V6DWT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chlorite dismutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13652</name>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="82"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="19320" checksum="5ACB03B880F7E4C9" modified="2014-02-19" version="1">MYATVLYSEADVDELFDEVEGLRGNFDHYGTHVKTAVYEGRHTDRAAVVSIWDTASAAETAGGFLSELPDIVARAGEESGFGTMGMFYTVKPDYQTEFVDTFDDVGELLAEMDGHVETDLMVNVEDESDMFIASQWNAKEDAMQFFRSDEFSETVQWGRDVLADRPRHVFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU0</accession>
    <name>V6DWU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="122" mass="12733" checksum="89D2E249DCB00214" modified="2014-02-19" version="1">MRDVLRLRGLLIHFCECVEFLGRLGGSFISDCSHGDHLQSPGREGSMRSLRSSSLTPFAPAVLASHVFALAAAPLSPTSHSTSPSPASSLAPSASLREPATPSRGAASRSPVATARRHAPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU1</accession>
    <name>V6DWU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7813" checksum="92B4242F72CC39FF" modified="2014-02-19" version="1">MLRRGEIKLLPTIITTDIGAEPSPSIRSSRRSRTADPRRRRSARLVDPPVTLIRPGRKANHRKCGVTASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU2</accession>
    <name>V6DWU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
            <ecNumber evidence="3">3.4.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_12862</name>
        <name evidence="3" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.5" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="3"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18040" checksum="9DADE0B0DAC411BF" modified="2014-02-19" version="1">MICGNSLGGAVALWIASERDLALDGLVLAGTGAKLAVADSLRDALATDFDRAVSLLHEPNRLFHDAPAEYVELSEASMRACGRAVTERDFLTCHDFDVRDRLDEIGVPTLALVGAHDELTPPAYHEYLADRIPDGEWTELPDAAHLAMLERPAAFNEALSEFLARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU3</accession>
    <name>V6DWU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_13925</name>
        <name evidence="3" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="556" mass="57949" checksum="058DD95CD2FFFEAB" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU4</accession>
    <name>V6DWU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_13163</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077364.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100804at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15433" checksum="5CCCA332CD10FA35" modified="2014-02-19" version="1">MSEHTTPATTRPSTRKRYKRIAYGLLGVGILALWIAIALDRFVLGVALYWAGGIGMGLVQRFSPVDLYDERDTTIEREAGHYTMKVFAYVFVLGAPGGLVLEESGIVTLPGEFYGSMWTLFALFVAYGAFVIYYKYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU5</accession>
    <name>V6DWU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_13088</name>
        <name evidence="6" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077376.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70625at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="174" mass="19173" checksum="4709A4BA7B47E16C" modified="2014-02-19" version="1">MSYQTSNPLVGETEFALDGPWATYWIAFLRVVTGWWFFHSGFTKILTDGFSYSYGPMYMSEMTGTALGPIPVWMGNNLAFLIEPGVPLFETLIGLALIAGAFTRFAAFGGVIFMSLFWIGNAEFGHGVVNSDLMGLLLFLTVIVLAAGRYYGLDALIEETALVKQNPKLRYLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU6</accession>
    <name>V6DWU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cryptochrome/photolyase-related protein Phr3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10286</name>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="275" mass="30468" checksum="CF72E018837B8579" modified="2014-02-19" version="1">MVVDGRYAGAVERVLDDDALAAGRWKHNVXXXXXXXSTSLDEFGDGDAATGGANDDPAPVPLNAAEGFIRQVIGWREFVRHVYREAMPELADANKLEQKRELPPAYWDGETDMECLSEAVGHVREFGYAHHIERLMVLSNFALVYGVDPGELNEWFHLGFVDAYHWVTTPNVVAMGSFGTDVLSSKPYASSGSYVNRMSDHCADCPYAVSRTTGEGACPFNALYWDFLKENEETLRGTGRMGLMYSHVDGKDDEEWTAIRERAAAVRELAAEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU7</accession>
    <name>V6DWU7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C470_04285</name>
        <name evidence="7" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + beta-nicotinamide D-ribonucleotide + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the archaeal NMN adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077370.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90722at2157"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02166">
        <property type="entry name" value="NMNAT_Archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00243">
        <property type="entry name" value="NMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006418">
        <property type="entry name" value="NMN_Atrans_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01527">
        <property type="entry name" value="arch_NMN_Atrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="176" mass="20016" checksum="73E194FAA75D7969" modified="2014-02-19" version="1">MRGFYIGRYQPFHDGHQHMVEEIAAEVDELVLGIGSAGDSHTTRNPFTAGERVMMVTKAVEELDATTYVVPIEDLDRNSVWVSHVQSMTPRFDVAYSNNPLVVRLFEEAGVEVRQSPMFRRDVLEGTELRERMIRGRDWEDLVPDAVVDVIREVDGVERIRRIAETDTNGEEPSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU8</accession>
    <name>V6DWU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6959" checksum="A0293B6D3BD01828" modified="2014-02-19" version="1">MVMYVFKYFTYKPPTSYIYPRVLLRLRGVEQAPKLDGRSRRRFVRQSWTGSETSNLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWU9</accession>
    <name>V6DWU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Binding-protein-dependent transporters inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13677</name>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13073" checksum="6503C28893789C57" modified="2014-02-19" version="1">MATETGSELDGDAAVAIGLDDPRRLLRGALGVAGFLAVWYVVSLGSPAYVVPSPVAVAGAFGSELASGDMTTALYQSVRHWIPGTVAGTASRGRQGTQGIGXXXXXXXGTSFVTVKLTFVNRQYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW0</accession>
    <name>V6DWW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_2975</name>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334954.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108890at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041025">
        <property type="entry name" value="HNH_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18780">
        <property type="entry name" value="HNH_repeat"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="518" mass="57923" checksum="DAE550907ADCDF84" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW2</accession>
    <name>V6DWW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_05205</name>
        <name evidence="1" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077388.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93321at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043815">
        <property type="entry name" value="DUF5797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19110">
        <property type="entry name" value="DUF5797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="168" mass="18939" checksum="CEE016E8813B64C3" modified="2014-02-19" version="1">MSLTDEERSRLADVVRLQPTKNGELQDAWEMDSGSEVHGYLEDHLKEYYYRDDDSLIRTTAEANDLVDVEPGVEPDAVAKGGVPETIRVPELEARVVEVLAGPEERSQSVVSVLNALREAYDGDPEVDAVRRALRSLERKNVVEVVYRTVPTFRLAVERDEIEVEISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWW3</accession>
    <name>V6DWW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="146" mass="16252" checksum="4684DBE5EFC3616A" modified="2014-02-19" version="1">MRTAIHYLLLFSVQLQHSLTVTATTATAQPYSNSNSNNSYSTAVSTKAASPDQITLLQNLYRVLLTAEVNIANSSVNRLFISISLPVPLKSNVLSRGYHGKLCHPWSAFLLIALIVQTSLSEIYLSVYKVIIQNNYIVYLFTKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX30</accession>
    <name>V6DX30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4777" checksum="53167FFE91D1DEF7" modified="2014-02-19" version="1">MGPRQVDDLARDAGRVRPARRVPRLRLRRRAFLTPVAPNGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX31</accession>
    <name>V6DX31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH-quinone oxidoreductase, B subunit</fullName>
            <ecNumber evidence="3">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10068</name>
        <name evidence="3" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077445.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54259at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="2">
        <location>
            <begin position="70"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="232" mass="25975" checksum="F893AF6AD82F1970" modified="2014-02-19" version="1">MSSDQPFITDESQVVTETRDARMTGQGDRFNSRLREAFGSSPFILTKFDKFLNWCRGSSMFMLQFGIACCSIEMMHTYAVKHDLDRFGSGVPRASPRQADVMIVPGTIVSKFAPRMKRVYDQMPEPKFVVGMGSCTISGGPFQEGYNVIKGAEEVIPIDIHVPGCPPRPEALVYGVVKLQERVANGEAAPVTVKPYELEQFSDLERDELVDKLTDQIDDDELVMRYNFADSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX32</accession>
    <name>V6DX32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trxA</name>
        <name evidence="3" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077831.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110723at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="11849" checksum="0DDDEEA17D89CD72" modified="2014-02-19" version="1">MSSTEAAPAEPIRLADTDAFDAHVADHDVVLVDFYADWCGPCQMMEPAVEAVASDTDAAVLKVDVDEHQALAGEYGVQSIPTLLVFSDGELADQMVGAQTEQALVDAVAEPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX33</accession>
    <name>V6DX33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal-transducing histidine kinase domain protein</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02849</name>
        <name evidence="3" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="330" mass="35773" checksum="DF19B473B9BCD2E6" modified="2014-02-19" version="1">MSDDADAEAGSGTVRVGGENVHAGDEAGPEERLKRQRDDLRLLNQVMRHDIRNDLQLVGAYAELLDDHVDEEGKEYLEVIKRNTQSAVSLTTTVRDLAEVMLRDDAEPSGVSLDHVLSQQVEEVRSAYSEAVFTVEGSFPAAEVVGDEMLSSVFRNLLRNAVQHNDETPPTVTVSATAEKADGVAEVRIADNGPGIPEDQRDEVFGKGEKDSTARGRGSACTWSGRSSRYTTATCGSKTTNRRARCSSSGCRSATGNASGRHERIHLVGTDYSSSYSIATELIQNRFPVGSGPSSNTWPRWESQFAHRTSVRDIPWLVSTVVVTDSSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX34</accession>
    <name>V6DX34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="6326" checksum="288C110A57199E9C" modified="2014-02-19" version="1">MGRRVFRPQHISQLSNTTKLYGRIQRLCGRERDRRNAGYRYRVDRRLLRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX35</accession>
    <name>V6DX35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_05751</name>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078294.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129051at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="6997" checksum="4E2556EC6F147312" modified="2014-02-19" version="1">MALLRRFEALSVQAQIVVVALVCDPIGFAAGYLLAPEFGLEPIVGGAYGLVAASLPLSLLVLREASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX36</accession>
    <name>V6DX36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8740" checksum="172BC7E43003D520" modified="2014-02-19" version="1">MTIASKRTIRTPNRRTAATKSNSPAVIPSAMLPKYPALSAPETTTYAPITGTRSGSGSKPPNGSDTVRPPPLGASTKLQRSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX37</accession>
    <name>V6DX37_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10123</name>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077500.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78441at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="9"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="18146" checksum="8B1FB9B34BE02F3F" modified="2014-02-19" version="1">MSDIHPDQRVAVLADSQNLYHSAQSVYSRNIDYSGLLESAVADRSLVRAIAYVIRADSPEEESFFEALRDIGFETKIKEIKTFADGSKKADWDLGMSLDAVSLASHVDTVVLCTGDGDFARLCSHLRHEGVRVEAMGFGNSAADELIEAADDFVDLAEDKEQFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX38</accession>
    <name>V6DX38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_10229</name>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077455.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98919at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="14265" checksum="3AC5A120FEBAB63F" modified="2014-02-19" version="1">MSHPSTEQIDELLSATRTATGDELRSLTYFTEDDVEQLYLRSDLSRTADLIGFAENERQGFRAQSLYANTQLGDYRFTVRVFENGYLTRVIANGHGAWLTTDSMEIDRFEELASALATILRSFDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX39</accession>
    <name>V6DX39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_02187</name>
        <name evidence="8" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077836.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35368at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="171"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="487" mass="49918" checksum="BE02409520DC2E54" modified="2014-02-19" version="1">MPRSFTPTAYEDLDPDRRPSLAAALVPVLAIVAFLGIGSAVLGLDPHPPLLWSIAFVGAFGLWLGYDWDDLFDGVANGLVMGLQAILIIFTIYGLIATWVSAGTIPSLMYYGLEILSPTTFLPAAAVLAAVVAFAIGSSWTTVGTLGVTFVGIGAGLGVPAPMTVGAVLSGAYAGDKQSPLSDTTNLAAGVTNTDLYAHIRRMRTGTAIAFGLAVIAFAAVGLRVSGSIPAGRIAEIQGGLTETYAITVLAFVPLVVTFGLALRGYAALPTLVAGVFAGAFTTILLQGAGFVAAWETFMYGTAPESASNTVNELLATDGLTGSAWTITVVVAALSLGGILERTGVLAVIAHAFTSAVRSPGALIAGTGISAILINALTAQQYMSIVLPGVTLRNTYDEFGMDSDQLSRAVEAAGTPTGALIPYHAGAVFMASATGVPTLEYAPYYLFAFFSPVVLFVMALTGYTIDVNPVSADDPGKTPTATPGSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX49</accession>
    <name>V6DX49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_02851</name>
        <name evidence="3" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="15864" checksum="CC475EB0D4A7BFBB" modified="2014-02-19" version="1">MTEPSGDQEVAQRRRRDRSXXXXXXXAKTNNPLFYFGSAGVASTASGAAMAAFVLYRYLAFGVSHEVIAVGAVGAIILGIQLLVFGVLADMIHSLHVEQIERYERSIDDRAAGRPSGTDGLEATEDRDSDARGAESTRREEPGDARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX50</accession>
    <name>V6DX50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10359</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="212" mass="23016" checksum="258D0636E4D63E4A" modified="2014-02-19" version="1">MRTQRRLTRVMQVVLVGIIVYGLFGSRYGLPGGGTKAVTNGTIGLLVTFIPAMLERNYDIPLDPWLGVWITAAVFLHTLGSAWFYAQIGWWDHLTHALSASLVAGAGYTAIRAVDLHSDEIRIPARFAFVFIFVVVLGFGVFWELFEFGLDIVADETGIDMPLAQHGLDDTVGDLTYNSIGALLVAVFGQAHLAGVADDIREGLFSDANSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX51</accession>
    <name>V6DX51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13338" checksum="F58BE7BE3D1B3BB3" modified="2014-02-19" version="1">MAGHTHTSPGVPREELARLLVSHVGRRRGDRADVAERVRLLLADEHLEPATVGRPRPAGVLASARLFDHTPRTDGSPNGVSRVLTAAKFARTGSGRTSAGLLGDVIERSARTATAAIPRENGPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX52</accession>
    <name>V6DX52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
            <ecNumber evidence="4">3.4.19.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_03436</name>
        <name evidence="4" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.1" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078286.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15633at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="393"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="601" mass="66556" checksum="E3EDFE541E10CCC5" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX53</accession>
    <name>V6DX53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5951" checksum="4A319980890E9803" modified="2014-02-19" version="1">MMGIIDSVRFSMKRWRLIVACSSQLVYPPVDVTRSFVSSKRGFSPRSQLSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX54</accession>
    <name>V6DX54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02282</name>
        <name evidence="3" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077846.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63240at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013971">
        <property type="entry name" value="HalX_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08663">
        <property type="entry name" value="HalX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20544" checksum="3B9A3BB672CB8166" modified="2014-02-19" version="1">MTEAPDATVLAVDDEPDLAELYRVYLDPAYDVRIATGGEEAIDAMDDAVDVVLLDRRMPDMSGHEVLTEIRGEGYDARVAMLTAVEPDVDIVEMPFDDYKTKPVTKEDLLTLVEVLLHRAAFDEQSQEFFALASKKAALEASGTTNSEEYEELIERMESVRLEVDDTLDLLSARDAFVEVPGEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX55</accession>
    <name>V6DX55_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycerol-1-phosphate dehydrogenase [NAD(P)+]</fullName>
            <shortName evidence="11">G1P dehydrogenase</shortName>
            <shortName evidence="11">G1PDH</shortName>
            <ecNumber evidence="11">1.1.1.261</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Enantiomeric glycerophosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">sn-glycerol-1-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">egsA</name>
        <name evidence="15" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NAD(+) + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:21412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.261"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NADP(+) + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21416"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.261"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the glycerol-1-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.261" evidence="11"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077470.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57545at2157"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106357">
        <property type="term" value="F:glycerol-1-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106358">
        <property type="term" value="F:glycerol-1-phosphate dehydrogenase [NADP+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00497_A">
        <property type="entry name" value="G1P_dehydrogenase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023002">
        <property type="entry name" value="G1P_dehydrogenase_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032837">
        <property type="entry name" value="G1PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13685">
        <property type="entry name" value="Fe-ADH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 12" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="11 14">
        <location>
            <begin position="94"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 14">
        <location>
            <begin position="116"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 13">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 14">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12 13">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11 12 13">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12 13">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CDK39955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="350" mass="36910" checksum="F6FDF3FEF925EEF7" modified="2014-02-19" version="1">MFEKTTWIKLPRNVLVGHDVLDDLGEAVGDLYLTGRPLIVTSPTPNEIAGDRVRAQFDDPATAVVEEASFAAVEELKETAEAVDPGYLIALGGGKPIDIAKMAADHLDVGFVSVPTVASHDGIVSGRSSIPEGDTRHSVAADPPLAVVADTTLIADAPWRLTTAGCADIISNYTAVKDWRLARRLRNVEYSEYAGALSEMTAELLVENADMIRPGLEESAWVVVKALVSSGVAMSIAGSSRPASGAEHLISHQLDRIAPGKALHGHQVGVASIMTEYLHSGENGRWNAIRDALAELDAPTTAGELGIDDAELIAALTSAHEIRDRYTILQGGINEEAAIEVATATGVIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX56</accession>
    <name>V6DX56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CopG family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_13842</name>
        <name evidence="7" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory CopG/NikR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078311.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90041at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RHH_1" evidence="5">
        <location>
            <begin position="2"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="NikR_C" evidence="6">
        <location>
            <begin position="58"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="131" mass="15390" checksum="2F186447A0787429" modified="2014-02-19" version="1">MRTSFNIPDEVVAEFDRVWRDEGIENRSRAVREAMSEYIESHSRLEDTAGEVVALVGFDYRHHDVIRELHGVQHAYQDVILNTSHTHQGEWCLESLFCRGAAERVRELTYRLRDFDAVRRVKVMMIRDGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX57</accession>
    <name>V6DX57_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7181" checksum="AB5F27094F619F28" modified="2014-02-19" version="1">MLRPRLDAGVGDASDVGCLRRDRDPRAGRLGDVAGRGCYLDRIARVRLEVHQNEHTLTRGARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX58</accession>
    <name>V6DX58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4986" checksum="326F14666AA4B037" modified="2014-02-19" version="1">MWDVRPPQPHRIKNVQIIRTNIGISQESLTSQVSTFNKSTTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX59</accession>
    <name>V6DX59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="318" mass="34615" checksum="83D18BBDD22613F4" modified="2014-02-19" version="1">MPAPEVVGEVDLGPDRPGVAGVGVRDGLADRRGGADHVGRLDDLAAALGVDDHADVVVLPADRLDVRLAEALVDLTVAVPEDHVVLDDVARVRRLRVPRVPLGDLVFEPQAVGRVLSEVLVGEEQHLVAPVERVLERVVGVRGRTDQPALLGAERLEVGVAVHVGDRDHVRVGLGSQFRPRRVDLEGLGHPGHRTGRLHAREDHLLSGVGDDVRGLGHERDAAEDDVLGVGGGGLLAQLVGVADEVRVFDDLPPLVVVAQDHHVVAERPQRLLDALRSLRFGERSVFRWKLFEVVVFEETEISLELRSFHCWHRRLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX60</accession>
    <name>V6DX60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="3847" checksum="5661EEE1A0F9EA51" modified="2014-02-19" version="1">MVTRSVGTAGGDGERRNYGAVGDGVPFSAVTSAAGACSTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX61</accession>
    <name>V6DX61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06803</name>
        <name evidence="2" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078315.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96414at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="13388" checksum="F5CBDEF2B8526B5C" modified="2014-02-19" version="1">MSDEAETDGEEAATDGGDEVLRASDLGGEGPPIDEKPYKIVFEANKCFGAGKCAEVADNWVMDVVSGMAKPETYYIGEEDLDENVRAAEACPAKKEAGVIHVVDRRTDEEIAPDPHGDGTLSVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX62</accession>
    <name>V6DX62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6338" checksum="EFDB3AA65310C158" modified="2014-02-19" version="1">MTKLLTPLETPGFVKNPATERRSIAVGSGPYARDRRIDGRMWTRRSARAGGRSDYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX63</accession>
    <name>V6DX63_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L37Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosomal protein L43e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rpl37ae</name>
        <name evidence="4" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078289.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="GeneID" id="65212119"/>
    <dbReference type="OrthoDB" id="122290at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_L37Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_L37ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_L37ae/L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9591" checksum="E8CE48DB34795697" modified="2014-02-19" version="1">MAEDKARSTGSAGRFGARYGRVARKRVQDIEAEMRNATVDGDDVTRKGTGIWVNEETGETFTGGAYRPETPGGRTVRRSIRAALADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX64</accession>
    <name>V6DX64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02352</name>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="25315" checksum="51D2F1036E682CFB" modified="2014-02-19" version="1">MTDESSGVELLRRAFLTGVAVVVPAVITLVVLAFAFNAVYDYLDAFSSAVVAVSPGRGLPIVGAIPREVAIEIATPVVFVAAILLLGAAVESSRYGERAVDYVDEAVERVPGVGSVYQGFRQMSDAMLDSDGGNFREVVLVEFPTEETYTLAFVTSETPEVIADHADSEGEGMRTLFMPMAPNPVMGGHVVFVPERRIVDVELTVEEGIRALVTSGVALXXXXXXXXYPLCALPPTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX65</accession>
    <name>V6DX65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5651" checksum="015157127D95674D" modified="2014-02-19" version="1">MRRRCDXXXXXXXVPVAPAEAATAAVAPPAVRTKSRLFIRFYSGRGALKPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX66</accession>
    <name>V6DX66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10404</name>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077474.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116698at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10149" checksum="F504662F06712BA9" modified="2014-02-19" version="1">MADEFMKGFALFTIGGLGWITFGGWYRTPSYYEVVQLVNPAEGVNTAYGEVGLLAGDMFFWLMILGALTFWVLIPASRQLRDSLSDDDAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX67</accession>
    <name>V6DX67_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">infB</name>
        <name evidence="9" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077859.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17053at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_A">
        <property type="entry name" value="IF_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004544">
        <property type="entry name" value="TF_aIF-2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00491">
        <property type="entry name" value="aIF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="10"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="597" mass="65109" checksum="C2B1C15084BD3A00" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX68</accession>
    <name>V6DX68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IIA protein</fullName>
            <ecNumber evidence="1">3.1.3.3</ecNumber>
            <ecNumber evidence="1">3.1.3.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_13912</name>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="1"/>
    <dbReference type="EC" id="3.1.3.74" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078319.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50266at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033883">
        <property type="term" value="F:pyridoxal phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="259" mass="27324" checksum="CA4397EEFDB026AD" modified="2014-02-19" version="1">MEFSGAVLDVDGTVVRGDEPIPGAPAGYRRLRGAGIETLFVSNNPTKAPPAYVDRLGAAGYDVDADRVFTAGSVTTRYLGRHHADDDLLCIADSGLLDQFAAAGLSTTDDVDAADALVASIDREFDYEDLCTALWALERDIPFIGTDPDVVIPAPERDVPGSGAVINAIAGVAERDPDAVLGKPSDTAIEMVRERLPYPPEECLVVGDRLDTDIALGERAGMTSVLVRSGVTDADDLAASEVSPDYVLDHLGEIDRVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX69</accession>
    <name>V6DX69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6903" checksum="C7463D4002610849" modified="2014-02-19" version="1">MNVREERRPRDGHTHRRRDEADRNPRWRAPPSALLWARGAPGEEVSRRSNAEATDEAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX80</accession>
    <name>V6DX80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_04836</name>
        <name evidence="2" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077479.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90425at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="158" mass="17709" checksum="2A0ADE400E458CDC" modified="2014-02-19" version="1">MVDESVIAALAGVSVTTSLPFLLYGAWIMIDAETVSWNVLMRHLRYIVAGLLLTTVPLVGWMIPRVLDQLTGMAILHAFFGVQAYAMLAFALTGIVRIFQAKRNADAYEDLDVDIDEIHEDMGHWRKRLRAGVAGFMLLWLCAWVTGVYRLLTLHFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX82</accession>
    <name>V6DX82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_15444</name>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078334.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129228at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14573" checksum="59B06ADA76010956" modified="2014-02-19" version="1">MYSTNVVYEVEFDILDDRRERFDAWVATDIIGWVGHESVAAFEVLTGGRRASADSKFVFEFETLQDWAAFVGSDRHEDAVDRLDALAENREATLWRRASVKLDAALDRTASERTDGGRDGRAINTVNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX83</accession>
    <name>V6DX83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9415" checksum="01A8801B41C77FB2" modified="2014-02-19" version="1">MNVRGFESSRYPVTTDESHIHTETAKRPVLSPLVARNAVGLADRDPPGRPLVRVDVPLEERHLAGAVVVIGPFTDEFRRPVANTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0A8</accession>
    <name>V6E0A8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5001" checksum="E49F8FEBEB12FBBA" modified="2014-02-19" version="1">MAVMPIPPITRRTCRRVLSRGGHVMPDGWSLPLKYPGENVSSLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0B1</accession>
    <name>V6E0B1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AsnC family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_10071</name>
        <name evidence="5" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078374.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000026.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93242at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK41030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15718" checksum="9C0606659B71B473" modified="2014-02-19" version="1">MDDLDRRILSILRRDARTPYTEIADRVGTSEGTVRNRVDRMTDEGVIERFTVTTRTGNVKAMIEISVEMNVNTDEVGQRMVDWEEVDFVWQVSGEEDIVLVVDAVDTRAVNELITQAREMDEVKSTKTRLILDERLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0B3</accession>
    <name>V6E0B3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TrkA-C domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05297</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078384.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100060at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026278">
        <property type="entry name" value="K(+)/H(+)_antiporter_KhtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005028">
        <property type="entry name" value="KhtT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK C-terminal" evidence="1">
        <location>
            <begin position="75"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="159" mass="17161" checksum="06F2ACE13322E05D" modified="2014-02-19" version="1">MTISESDLPGVGKKFEIDLGDEEMIVVIHNTGKREVFRRPDPDDDSEKVFAFDDDLARKIGSIIEGAYFQPVEPDTQETTLPGGILLEWYELPPGSPLVGETLESADIGNRTGLAIVAIQRDEGVLDSPGAETTLREGDTLIGVGTPENCAAFEEILTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0B6</accession>
    <name>V6E0B6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4533" checksum="BBB32AA3ED07F5E4" modified="2014-02-19" version="1">MSRSAAGTALPEADGHRGPKPANAASATLTPKTAGTLGGHKNPRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0C8</accession>
    <name>V6E0C8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division protein FtsZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C465_12973</name>
        <name evidence="4" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11895" checksum="7A4AE8576807D1D3" modified="2014-02-19" version="1">MMTGLSLPSATDADAALVAVAGDPDRISRKGAEKARKWLQEETGSMQVRGGDFPLDSDRIAALVLLAGVERSQRVEAFLERARQAVRDEREEKPDPAAAFENDEIDDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0D1</accession>
    <name>V6E0D1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C464_01978</name>
        <name evidence="7" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078403.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000028.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61149at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="97"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK41058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="330" mass="35440" checksum="1081AE89A2655B87" modified="2014-02-19" version="1">MSFGRFVLKRSLQGVGVVWGVITVVFALRFVTPGSPINAVAPLDATQETRQAIAAELGLDQPLYIQYGQYVFDLLQGDMGRSYIKGQEVTTLVFERLPATVELALAASVVAIVLAIPLGVISATNRNEPVDYGATLLSLGGISTPNFWLGIMLILIFAVEFDVFNTSGRGVDVGDVALSVISAEPFVGTLLAWLAYITLPAIALGTYFMALITRLTRSGMLDELSKGYVQAARAKGLPRTLIRYKHALRNTLIPVITVLGLQLGTLIGGAVITEAVFSWPGLGTLVIESINQRDWPALQGSLIVIGTSFVLVNILVDVVYAYLDPEVVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0D3</accession>
    <name>V6E0D3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="4939" checksum="BA7DCD9B72B03727" modified="2014-02-19" version="1">MSGVRCASRGGNGAVFGLRLAAELTDATAARGVFFPSDSPVVLWGITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0D5</accession>
    <name>V6E0D5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil/vitamin C permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_09408</name>
        <name evidence="8" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078407.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000028.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29114at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026033">
        <property type="entry name" value="Azg-like_bact_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005353">
        <property type="entry name" value="PbuG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK41063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="459" mass="47779" checksum="AD2EE1D61AB9B03F" modified="2014-02-19" version="1">MGLTDTLAERFDVESHGSDVRTELIAGLTTFLAMSYIIVVNPAILSEAIQIEGYGQGEVFQMIAIATILSAALATAVMALYANRPFGLAPGLGLNAFFAYTVVLGLGIPWQTALAAVFAEGVLFMILTAVGAREYVIRLFPEPVKRSVGAGIGLFLLFIGLQELQIVVPDDATLVTLGGIFGNPWAILGVLGLVLTFVLWARNVTGAIVLGIVTTSLVGWGLTLAGLFDRGTITPTSLPSPQYDITPLAGAFLDGLSGIDPLTFVLVVFTFFFVDFFDTAGTLIGVSQFGDFLDEDGDLPDMDRPLMADAVGTTAGAVLGTSTVTTYIESSTGVEEGGRTGLTALVVALLFVASLVVIPVVAAIPAYASFVALIVVGVMMLQGLTEVDWADPAWAVSAGLTVTVMPFAYSIADGLAAGIVAYPIIKVAVGEADEVALGQYAIAALLAAYYVLSTRGVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0D7</accession>
    <name>V6E0D7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ribE</name>
        <name evidence="4" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078396.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74349at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="114"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="114"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="22685" checksum="1E650C6E0DF1C1F1" modified="2014-02-19" version="1">MFTGIVEGTGAVRARTETDDGLRLKIGVDGVEGFDDLARGQSISVSGVCLTVEEHGVGGGDGAPDDGSTGDSDWFEVFLASETVAKTYLGEVREGDAVNVERAMPADGRFDGHVVQGHVDTVSEVTAIERVGEDWRFTFSIPEGHDDYLVDKGSVTLDGISLTVAEKRDGEFDVAVIPTTYDLTTLSAKSVGDPIHLEVDVIAKYVENMVGGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0E0</accession>
    <name>V6E0E0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6653" checksum="DEA1C533F7500C93" modified="2014-02-19" version="1">MRWRAPPSALLRARGAPREGVGGPKRSGGPATRLGRREVLCGRVGLEGAAGRRAEAFTRAKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0E1</accession>
    <name>V6E0E1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6189" checksum="18F490D8D52F67CA" modified="2014-02-19" version="1">MTDTPSLALRYVVCDACETVFALPDDPDEPDVCGRCGRRPLRELPDVRGSDAYFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0E3</accession>
    <name>V6E0E3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="316" mass="34281" checksum="74A526B9B7C97408" modified="2014-02-19" version="1">MGRHVLHLAFQEGEGDLVLRAVHRAVVDAVGLDEEVDAAAVVVVRPAGAAEHLGELLNGEPLDPHRQRVEDHLRGGEVDSGRQRRGGDDRGEVLVTEHALDLLPAAVIEPGVVRRGVVPELAADLVTAPPRVREDDRLAAVPLRRFRVELPFDELVRYLRLLAAVGEGDVSLDWDGSLLVLDERRPELLREPLGVPDGRREVDELGAVVARMRLHPVLAVVLQPRDEAVEPVAALALLQGVDLVDDDRPHVAQILPGPERVVDPLVGADDHVGVRVEPVAVVVHPRGADPDGHVEQVAVAVLEVLVFLVGERDERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0E4</accession>
    <name>V6E0E4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8134" checksum="5412DAE8359A4886" modified="2014-02-19" version="1">MSQTRERYEPIAPRERPSLPSAGDPLTRESLVRPCYRLISPVIGDSRRPTSMYVRDRMPSTCATPEPGGTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0E7</accession>
    <name>V6E0E7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="7899" checksum="E40CA9EF0C75BB29" modified="2014-02-19" version="1">MARACERPTGREPARARESGATEGDRREPEGCARRGWGGVRCGCGAGETQRGSHEAGIGVHESEALVSQSERGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0E9</accession>
    <name>V6E0E9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="8129" checksum="0A394FA536A8AA96" modified="2014-02-19" version="1">MSNGFSSSLIHNIRYCQHMNLYQTAVDRSICMSYMLTDLVITTPVSTVQDTRVVFSTRFLSRMKDFNRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF0</accession>
    <name>V6DSF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Concanavalin A-like lectin/glucanases family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="227" mass="25132" checksum="4CBF017755B01165" modified="2014-02-19" version="1">MIRDGGIVVDPTMKPEAGVARWTLSPEDTDGTTALDTWGDNDGAIYGGVQPNVETDVGPAYQFDGSTGHVVLGSVESLQLDAAYTVSQLIRFEKQQETWFFGNYDTEDRGAGITYDREGSGRIRWYDGIEFFTLSKPIETQRWYLVTLSRSGSTYTLYLDGEYEGSITTSQTGFSDSSRPNVTIGSSWGETRTDHRAPLHGFMKNIQIYAKEITSEEAARLYSQGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF1</accession>
    <name>V6DSF1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">16S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C472_01127</name>
        <name evidence="10" type="ORF">BN903_159</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an N(1)-methylpseudouridine in 16S/18S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyl-N(3)[(3S)-3-amino-3-carboxypropyl]pseudouridine in 16S/18S rRNA + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076297.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113131at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:18S rRNA aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="PTHR20426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RLI" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Ribo_biogen_C" evidence="8">
        <location>
            <begin position="40"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK38485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="167" mass="18843" checksum="6644AFAD9C39C91C" modified="2014-02-19" version="1">MDLHVRYEGDDDPDKCTARKLARFDLAELHRSDRATPYGVVLNPHAERALSPADAERARENALVALDCSWESAGEKMFSLPGEHRALPYLVAANPVNFGRPMKLTTVEAFAAALILLGERDHAERILSKFTWGETFLELNDEPLRRYADCEDSAEIVAVQQEYLDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF2</accession>
    <name>V6DSF2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_01684</name>
        <name evidence="2" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zinc_ribbon_2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5932" checksum="8B9147D0904209EC" modified="2014-02-19" version="1">MRRKQFIQQIVRLEPSSTTHHECRHCGYTVENNANECPQCGSHEIAAYDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF3</accession>
    <name>V6DSF3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HalDL1DRAFT_3151</name>
        <name evidence="7" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076851.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="REBASE" id="80601">
        <property type="entry name" value="M.HspAJ67ORF102P"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58937at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="371" mass="41395" checksum="41F3201995ECFA60" modified="2014-02-19" version="1">MKVAAVDLFCGTGGLSYGLQQSGISVVAGIDKDPDCKYPYEQNIDGEYVRADVHALARDPEPIAQMYPWDADLKILAACAPCQPYSTMGHSKGKDHEDHQKWGLLNEVSRIVEYVQPDVVVTENVLQVKQEDGVYDSFIESLESQGYHVNSDENKNVYCPEYGIPQKRKRWVVMASKRGPLSLPDPPIQNEDDYPTVKDAIDHLPPIEAGEVCDKNDVHRARSLSEKNLKRIDNMEPGGDWTLWEEKGLDHLLADCHRKASGRSYKAPYSRTRPDEPSPTITTQFYNYGSGRFGHYDTDQNRALSILEGALLQTFPEDYEFYDDWEDVGVSNLGRLIGNAVPPKLGEYMGQAILSHVGAAVPSVESTVADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG8</accession>
    <name>V6DSG8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HSB1_39200</name>
        <name evidence="1" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076854.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55987at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045920">
        <property type="entry name" value="DUF6339"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19866">
        <property type="entry name" value="DUF6339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="229" mass="26572" checksum="67006E3932C510EA" modified="2014-02-19" version="1">MTETELHRLTEDGRRLVGESFMKGETTLTDEQLNEYVEPMAGRPTADLNRIDSTVKEVLEEYPEYETAIDGSLAEEIHRSLNITRRTAGDPGLWHWLAVVQYPDLVRYRWEYRSEEAMREKFLGAGSDLYSNAIHRLWWIAELTSRGDDYSTTDAVFANQTMVNKVFDRWFARYQPAVRAMCDELADEPSRVIDETTRRFNHALTNVQLEGLSEDEAREMIRQIIAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH0</accession>
    <name>V6DSH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="13577" checksum="CAD99EB2493CD7DE" modified="2014-02-19" version="1">MVVYSRDVHRSISDLPESHTFSVSYQYSNRGYRNIVLYSNPKTVIGTKEVGGIEQKCANSELPYWEVGGRIDGWTRDSHVGPGDGLANRHDSTGSDRAVRRLRWSRTALRSVSHETLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH1</accession>
    <name>V6DSH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6965" checksum="CF92A8350238CE74" modified="2014-02-19" version="1">MDFGSGTYNWKIDREDGHVYDSAEATFDPLVASEVGQFCIHASHYGKGTGNFYVDDISISDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH2</accession>
    <name>V6DSH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="8034" checksum="11E990D1699392B6" modified="2014-02-19" version="1">MESRYSLLIGGADTLSSLLIDDQIRHSFITTGVSLWTRGVCCASDTRFLSCSLREMINYRVQITLWTKGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH3</accession>
    <name>V6DSH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell division control protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_17675</name>
        <name evidence="3" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076859.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="39"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="38810" checksum="AFC523A56912D4CE" modified="2014-02-19" version="1">MIRDARVLRAGFVPREVEHRDAEVNHLSSVLKPITNGEPADTAIVTGPSGTGKTCISQFVTERLREEVLDVEAIYVNCWRNYTRFRTLYQILDNLGATIDIHRQSTPHDELVDRLQQHDGPRTVVILDEVDQLEDPSVIYDLHSLPQFAIICIANKEEELFSRVDDRLVSRLRSSEHVRMDKYHDEQLYDILSARAKWGLDEGVITDDQLYRIADAAAGDARLAIGILRTAAGKADRENHERITDDILLDAAEDARAQIKQKSLDSLTPHQRVVYDIVGEHGPVGPSEIHERYSEDVDDPRTKRTIRTYLSKMEQYNLLEAEGTSRDRKYSLVDSAAASPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH4</accession>
    <name>V6DSH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C496_23121</name>
        <name evidence="1" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076841.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130243at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8708" checksum="D947FE27CDB49914" modified="2014-02-19" version="1">MSNDVSDEQTARELANTYADSECVGQLGDIIDIEEYDTEWLVEFETHTLSDTYTHHVRITKSVGNVISHDRSSRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH5</accession>
    <name>V6DSH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5133" checksum="3F1037A7136A290F" modified="2014-02-19" version="1">MGLEGAAARTKHGEARTARSEHRERLRTAASRASPRGWGFGVVRVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH6</accession>
    <name>V6DSH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_08740</name>
        <name evidence="3" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076867.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110514at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="78"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="15298" checksum="080CFB67CA4DB40F" modified="2014-02-19" version="1">MIEIPDSLRSVFSAQLEKRDGSYVVDVPASETEHDALAAGETYRIATLASDSSTGQKIQQEQHQSAAQETTPTSDDPPVNKGEVRDVTIETTGDQGDGIAKVERGYVVIVPGGQPGDEPTVEIEQVQENVAFASIVEQDSRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH7</accession>
    <name>V6DSH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076015.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="183" mass="19971" checksum="D2E1361D8B86EE5F" modified="2014-02-19" version="1">MHLHEHDDTHLWEGPFAALAAGQIDAATDDVLILAEDESEVRRLHSDIVTELGTPIAHAETYAGAQEELPFDVDTFDVSVQVNPSRSPFKRHQPLYQASAVTRPNGTIVYKAPRSLAHSEAVEIDTIYALNWKHHETPSLAALMTVSLAGTLGETNPTATASPSRPSHEQPPETEETTITSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSH9</accession>
    <name>V6DSH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3100</name>
        <name evidence="1" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076846.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55103at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="231" mass="25699" checksum="7795346845D5101D" modified="2014-02-19" version="1">MSFNNRSDALIELLEELTQAGHEYVLVGGYAVSAFNARFSTDLDIVVAPDSKAKFAEFLEGQGFEETDSHTKEWFYDTEVIEYEKRLTPQQPIGFDLLVNGLGCRQTEAQWSFDYLYDHSHQQEVSGGTVTTRGRVIDGAVLVAAKLHSGRETDLRDVLAVAEEIDLDAVTPHLRRGDDDALRDQLERGLEILESDELKHGYRSDFGASAVSEGTVTALQEYLSAQIDHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI1</accession>
    <name>V6DSI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C437_14824</name>
        <name evidence="1" type="ORF">BN903_132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076872.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38036at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="333" mass="37413" checksum="E3D9889FA17B4AA5" modified="2014-02-19" version="1">MSPDLSVSTSTDSEIATARQVDRVAFLHRAPFVLDGLALGFLPGFREDCGYQADQYLDLDIPVGMLDNDFRNPDLDRFVDRFFEYEPQVGVIGDIYERDDVDAHVAAARGIQASYPETDLIIVPKSRAVIDAIPEDLVLGYSRGYADRLAHEFSDPADWRGRRVHILGGSPPKQLEVIRQLTRPTLSADPPADIVGLDWNGLHRGAQFGEFWTANGWDDSGRDADHVTIRKTVRHSLARIREFWKSHGIWPESTPQDEGVHIEYEGPTPADLGHAACTECGTNVWRTRHGPYVAEYDTGAICGYCSYECYFRHRHRNNLEEIAGERSVYIPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI2</accession>
    <name>V6DSI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Branched-chain amino acid ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_14207</name>
        <name evidence="3" type="ORF">BN903_190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076318.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="23746at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="65"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="474" mass="49573" checksum="38AD5E5A83E863F6" modified="2014-02-19" version="1">MRDDHTRRSYLRRTSAAVGAAGLTGLAGCSGGGDGSDGSDGSDGGDGMDGGDGGDGGDGDLSGETIRIGALQPTSGDLQYYGQISLRGFYSGLAYKHDLDPIQEATPGTYTVEPDGGPTYEIIVEDTGFSPDTAQSVATDLVVDDEVDVLFGGTSSDSARRVIDTVVDETDVPYLIGPAADAGITVSDEFCHPLAFRASEHTAMDARAGGTYVAENFDINTVAIFASDNAFGQSVASNYAEVLEANGVDVLEPRFVEVGYSEFDGLFEQAVSDGASGVVGGFTASTLPQFLTSAISYDVQVFGGFAALLTTQLIGGTIQSELGEDFTAQDIKDAGLGPFTSRYHWNQYENPINEEFRQMHIDAYGIVPDLFSSGTFTAASALSQAVSEAGSTDGADVADALRGMTVADTPKGADGYTFQEHNNQAASQMTVAWPVPTSDEYADTWDAPIMPGEPEQRLDAEDVMVPEEDASCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI3</accession>
    <name>V6DSI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halar_0404</name>
        <name evidence="2" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076948.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78590at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="279" mass="29892" checksum="7DA7C4B71DF20D91" modified="2014-02-19" version="1">MLLPQLDDGITLLNVEGGRGVPILQSLVLDHLLLHDGPAFWIDANGHATTTTLAQIAPSQRLLNRIHVARGFTAYQHYGAVCDLPTAVNKSIQMSTTDAGAAGQGEPSRDEDTSPHTPALIVAPAVDAQYRADDTLGENHAKTLQARTLARLATYAEGYDISVLVTRNERNEFTESIATVADHHLECEQTRMGPRVVGEDFETLVYPVNDGAYYQTTFAYWRQLLAARATQVGVEPTTSAPSTPTPEGVRTGVTADSETVAATADPLLDAWTATGTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI4</accession>
    <name>V6DSI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5487" checksum="816419ECC5541E90" modified="2014-02-19" version="1">MIENAAQILFEFASSEISTYAATVGRGHDFNGISHVDTVRDLAIATQFAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI5</accession>
    <name>V6DSI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C489_19071</name>
        <name evidence="2" type="ORF">BN903_137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334928.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123514at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11477" checksum="794DE749363C72AA" modified="2014-02-19" version="1">MNNLLLIQVGNLSSTDILLLLSDYLTIGIGLIIAYIAYQGYSRNNSRPMLYIAVGFVLTFGGPGVIFLASLVIPLPSLVVGVATRLVEILGMGTILYGFIVPSQRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI6</accession>
    <name>V6DSI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01032</name>
        <name evidence="2" type="ORF">BN903_195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076322.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42446at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017533">
        <property type="entry name" value="Halocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03102">
        <property type="entry name" value="halo_cynanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Copper-bind" evidence="1">
        <location>
            <begin position="80"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="1">
        <location>
            <begin position="229"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="318" mass="34453" checksum="2E4012A84B78FF1F" modified="2014-02-19" version="1">MSRTPSTSRRRALALAAGGTLGALAGCLGSLDPIGGGNTDSGDGFTDTTDVPEPEYGHWFDGGTDYAGTVDRRGEDEVVIPVGDGDGFRFDPAAVWVDYDTTVRWEWTGESGVHDVVTYDGPAAIESELTDEATHEYAVTLTEADEGVTRYSCRPHQTIGEQGAIVVGPEIESYVTEYDTTPVDYGDWFARTPNVSETANPLRRDAVSVRVGGPGGYDPEAEEWETAPVYDTPALRVTPGTTVRWRWVPGAGEHSVVAEDGSFESDLVAVEAADSPEYQEDEHTFERVFEDPGIHEYACERHRDDGMRGAVVVAESRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI8</accession>
    <name>V6DSI8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C488_08022</name>
        <name evidence="2" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076866.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="53583at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="308" mass="35847" checksum="5B92086BD822C96D" modified="2014-02-19" version="1">MLRRIELEVLATVDRGDTISELATKLDHSESYLSRTVSDLVEKGLVYTERDGRRKRVVPSDARAVERYQDLVRQHSHIEFPELLTGKALEVLYYLDQPRTVAEIADRSDNYRNTVNRVLKRFCDRGLVGTDAGRYEFNADFDRLYEFARELAHHLHRHRLEVVAQKGTILWENYDEFLAQAEMEINADEFHETGLARFAAFNLRFLLTGHRYYFYDGEPDVVSPAELCCHTLLIDDGSRHRSYCLLLLSHVDVNEDDLCEQAAKYGLEDEIDALLQYLETHGEIEDSHLPEWSEFQELAAEYEVDLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSI9</accession>
    <name>V6DSI9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C445_06710</name>
        <name evidence="3" type="ORF">BN903_142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076880.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75104at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_11" evidence="2">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="251" mass="28197" checksum="0FADF029675E1F45" modified="2014-02-19" version="1">MSLPPWISEQLPENGRVNTKLTQRHVVETMYQSDRPFFSLQQIQQRLKPDVSKVTVRNRLDDLEDRGIVATDPLADSLTLYYIDHPESEWPLSPAGERALNRESAETGNPFREFLQHPLVNRVFREELLRSIAWAAIGLFGWAILVSSSGQLPATIWTVVGLPILTWASLTVGTIGVRLMTGNNLRVQSTEGLDTISLGGVVLGGFWAVFLIVVLDWSPLVTSGLYLFVTATYLVFYKRVIRPRFDASVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK0</accession>
    <name>V6DSK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Natpe_3996</name>
        <name evidence="1" type="ORF">BN903_152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076952.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78527at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="18309" checksum="ED99FFCB1BA8F412" modified="2014-02-19" version="1">MHIVIYTLVEASTHDDALATGKTVFDQLVGADPHASAVFDYYVTFDEEDTSVAGKARWGELPTAAPVDSDDGQDLLERGWEATNEAFERNLERVKDALNELSDEAIMRDRDLARHAFHQVGAYDGPTIFLYDEYANGIRHRGQLDRVLEASEELWIVPADVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK1</accession>
    <name>V6DSK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5358" checksum="4C3244EAD9E59C45" modified="2014-02-19" version="1">MNGSWLLEVLFSTPSTVVQTAVFHNQGPAAAALFQVFVQAEIGSWYDGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK2</accession>
    <name>V6DSK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_00898</name>
        <name evidence="1" type="ORF">BN903_210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076334.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113011at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="9361" checksum="E39BEED73E299226" modified="2014-02-19" version="1">MTEIAIEYAAGNRLRSEAETARRLIDAYLGDRPEVDRVTLSPSSESVFCVSVEGDRIWCTDPREWIDAMEAVTAARRRLSELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK3</accession>
    <name>V6DSK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7691" checksum="4E0EF7EABF94DE1C" modified="2014-02-19" version="1">MAEGVLDSDFDASKARSYRNGFAVALLAGFIVLSYQYWAIGELAIETMGIFFSAAFVFIISQFFYTRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK5</accession>
    <name>V6DSK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4493" checksum="8D9E26F2AE63EE80" modified="2014-02-19" version="1">MIFIEAFRAVFLVLVFAVLVFVDLGGKRLTNTPPSIRADVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK6</accession>
    <name>V6DSK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="6057" checksum="F87FCAC12FC9D1A2" modified="2014-02-19" version="1">MRTSVRIKRDLVYLFIVLLAGRTRIRATRAGRHRQRSQRWPAIDRPNRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK8</accession>
    <name>V6DSK8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9867" checksum="5A5A2C7C334A1EDB" modified="2014-02-19" version="1">MFCFSCQKYHFNMYIGFFMYLDSIVFARSSITEIAKSIDSQKPVGFRITFRLTKRYRRSVFLDFRDKYDFIAPFLLIYLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSK9</accession>
    <name>V6DSK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_17630</name>
        <name evidence="2" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076865.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119938at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="12400" checksum="2A0ED7DB7058CAF2" modified="2014-02-19" version="1">MSDEPPTPPATLTTEIVNTLNESEPERLREIATYAEALADHKEREARLKESADEEPVEERPDDLPDDVPAKATITIKEINDNRYYYWQWRDGEKIRSQYKGPVNPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN3</accession>
    <name>V6DWN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_10893</name>
        <name evidence="3" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.57" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078106.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66448at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="43"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="405" mass="43012" checksum="F886414A7189FFCB" modified="2014-02-19" version="1">MSVVEGVDAESASEPNASESNVPSSTEVLVVGPAGSRTEGTGGIGRYIAEQRRHLKGRVSLDVVDTAVRTPERPVEYLRTAAVLLSVWVGFLARRRPDIVHVHTSHSFSFYISAPYVLVAGLLWNRPVILHVHGSSFDTFLEDASPLAARFQQTVFGACTAVVALSDHWRDVLATRVPPERIVVVPNAVDPDEYDPDPAADPPHLVFVSNHIERKGIVEVTEAVDELQDSGLRFRATIAGSGPLSGHAEAVAEAHDAVDYVGFVSEERKRGLLGEGSVYVLPTSAEGLPIAVLEAMAGANAIVSTDVGGIPSIVDESNGALVAPGDVRGLTDALEELLSDPERTERMGRASRRRIEESYAWPDVVDELLSLYARALSDAEGANDDSAANDDGSADPDGAGVGVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN4</accession>
    <name>V6DWN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase M29 aminopeptidase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_10627</name>
        <name evidence="1" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="242" mass="26457" checksum="2C6EA647350BCC55" modified="2014-02-19" version="1">MSTVHPTRSLAQQAGMAYEEYQEFVYDAVLRDWEALADEMAKMKDILDDGEEVRIVTERDDAPDTDVRMSIAGRTAVNSAASVAYDSHNLPSGEVFTAPYDTAGEVFFDVPMTIDATRVRNVHLTFEDGEVVDFAAEAGEDALANVLDTDPGARRLGELGIGMNRGIDRFTDSILFDEKMGDTVHLAVGRAYDACLPEGESGNESAVHVDMITDVSADSRMEVDGEVVQRNGTFRWEGGFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN5</accession>
    <name>V6DWN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_05828</name>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077332.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6644at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="448" mass="49267" checksum="02AFAA0357CB98B9" modified="2014-02-19" version="1">MGLFDRLRGSDTPRVAFIGIDGLSYRLVADNPETFPTLSAIADGGGGGGIDSILPAESSACWPSLTTGKNPGETGVYGFQDREVGSYDTYVPMGRDVQAPRVWDRATDAGLDATVLNVPVTFPPQRTVQRMVSGYLSPDLDAAAHPEELREYLTGSDYRLSVNAKLGHKADKTAFLKHARETLDARAAAFERYVERDDWDLFVGVFTAPDRVNHFLWSDYEDGGTYREELLDFHAALDEHIGSIREALPNDVTLVVGSTHGFTRLDYDVYCNEWLEREGWLSYEDDDHDALADIDDDARAYSLVPGRFYLNVEGREPNGVVPEPEYEETRAELREALESWTGPDGNPVADRVVDRETAFRGDHAAIAPDLVVVPNDGFDLKAGFRPNDGVFDADGPRTGMHAFGDAALFVDHPDAAVRDADLLDVAPTLLKLLDIDYGRTDFDGASLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN6</accession>
    <name>V6DWN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MgtC/SapB transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C473_15546</name>
        <name evidence="8" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077324.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76036at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025105">
        <property type="entry name" value="DUF4010"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13194">
        <property type="entry name" value="DUF4010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4010" evidence="7">
        <location>
            <begin position="183"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="415" mass="42974" checksum="53BB88E790C59548" modified="2014-02-19" version="1">MMGAIDPFVYLETNVAKLVLATALGMFLGLEREWSQKSAGIRTFALISLAAAVFSLLDEPGLLVVGGVSVVASAVLLAVRSFVETDVDGLSLTTSASMLVAYGVGVLVAQGLFIESVTVAVLSSLLLVLKRELHEFAWGLSREEVRSAVEFTILAFVVFPLLPAETVDPWNAVQPRLVWSLVVAVSAIGFVNYVLVKRYQGRGYAVTGFFGGLVNSTAVVAEMAKRAKGRADLGEIAVGSILLANAAMAFRNAAVVAVFVPEAALVVGAPLGAITVAGIGVAVWRSDWRTTMEAELTSPFSLRNALTFGGLFLVVLLVSAVAEETFGAGGFVATSFLAGLVSSGTSTTTAVSLLGTGQIGVDTAVAGVVAGTAASILIKTAFAASIARELVRPVFLWNLLLIAVGVIAGIPLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN8</accession>
    <name>V6DWN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAS/PAC sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06774</name>
        <name evidence="3" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="83"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="174" mass="17545" checksum="02F8B6C1597B5366" modified="2014-02-19" version="1">MTLRPSDTSTPGRGGDEGEVPDTDERTATDAPANARDGFVPPAERAETDGSPSTSAGIDRASGGVGGTPANGASRPREADRFLLAVAVDGEVLFAGPSVPDVVGVEREALVGTDLLDRVHPGDRVAGGXXXXXXXLSPVCLASHDCWSEEFGGRSSPSGASTPTAPSRSATAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP0</accession>
    <name>V6DWP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, is605 orfb family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C482_02526</name>
        <name evidence="5" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077336.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75656at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="276"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="349" mass="39856" checksum="E1DC33A46253E539" modified="2014-02-19" version="1">MITVTVTAKFHNPSLSRRREWQHASRLYRDTKQFCIDGWENGDFGKSVTTASIDNDLYSAIQNQAIREAKSDHSKDGAVRYRESQPFAVNNQNWEIDTTENGSVVVGFPCVSQWWYTPIEVYDDIVDPVDRLVEGDADKTRLQIYRRGDDWYCTFNIEYDADTSGETPIGIDIGERHILAATAYGEDESMLVSGGEAKYVRRKYRSLRDSLSEAGALRARNRVGDKEQRRIKDLNHKLSRRLITFAEQFENPVIRMEDLEGIRENSSWSGVHSWHFHQLQQFITYKAEYAGIRVEKVDAYHTSQKCSVCGSMGTRDGDHFSCSECGRGRHADLNASENIAQREGEPCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP1</accession>
    <name>V6DWP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division protein FtsZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsZ</name>
        <name evidence="7" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin_C" evidence="6">
        <location>
            <begin position="50"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="186" mass="19927" checksum="E67CC2F1748BFFBE" modified="2014-02-19" version="1">MSDTVIVVPNDRLLDAVGKLPVRQAFKVSDEVLMRSVKGITELITMPGLVNLDFADVRTVMEKGGVAMIGLGESDSDSKAQDSVKSALRSPLLDVDISGANSALVNVTGGQDMSIEEAEGVVEEIYDRIDPDARIIWGTSVDDELEGEMRTMIVVTGVESPQIYGNNGEPPEGDAPSDVEDIDYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP2</accession>
    <name>V6DWP2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methionine synthase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">metE</name>
        <name evidence="4" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the archaeal MetE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078154.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21172at2157"/>
    <dbReference type="UniPathway" id="UPA00051"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00288">
        <property type="entry name" value="MetE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022921">
        <property type="entry name" value="MetE_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Meth_synt_2" evidence="3">
        <location>
            <begin position="25"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="357" mass="40309" checksum="D1BE78C142F6808C" modified="2014-02-19" version="1">MARNPAANRDQFRPDDHPNDTFLLSTVVGSYPKPKWLNRADELVDDPDSKFDDSDLEEAHDDACRLITHEHERAGLDTVVDGEMRRNEMVEFFADRIDGYEFNGPVKVWGHNYFDKPSVVEEVEYDEPWLVDEFEFTSSVAERPVKVPITGPYTLGFWAFNEAYPSTEELVYDLADLVNEEVEKLVEAGARYIQIDEPALATTPEDHAIVGEALERIAAGIPEEVRIGLHVCYGDYSRVYPEVNDYPIDEFDIELSNGDYEQIPVLEEPELEPDLALGVVDAHTAEVESVEEIKRNIRQGLRVVPPEKLTISPDCGLKLLPRDIAYGKTENMVTAVREVEAEIDAGEIDLDNPLADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP3</accession>
    <name>V6DWP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5508" checksum="17DA2ECBA0A47931" modified="2014-02-19" version="1">MMFGTGPSLACVREISLMSVVGVGVATEAIPDGLESRATQRGGDARPRRDGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP4</accession>
    <name>V6DWP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CbaC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13342</name>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7261" checksum="272096E074C7B3D2" modified="2014-02-19" version="1">MSRGGLLVTLAIFGVIVYEMRTVLDFVGVELPIIPYMAAVFVLAGAVVWYVSLMGGWRTEPEGDDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP5</accession>
    <name>V6DWP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Matrixin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05591</name>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M10" evidence="1">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="286" mass="31867" checksum="FC2344D5B57F8582" modified="2014-02-19" version="1">MVVATANRTRERAVTLTHPSPYGKTTLRLYVDDEAVDRNVSGVVAAATGYWERTDERYLGYPVAYERVSDEERADVILRFDRVDRCGVEDGDARYFGCADLLVDEPRTPMTATVEPNISDAEMSATIIHELGHVQGLEHGEEPADLMAPTSNLTTHRPVKVHLRAESGDVPRRVEDEVAAGLDYFADSEDIVGSDGFAWEFVDSAREAHVQITYDDRGNICFADGGGGSCTVEGEYYGQQDVRLEEIDDEVVAWHVGASFAPVLLEEVPPELMRDADRREREEWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP6</accession>
    <name>V6DWP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HTR-like protein</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_02348</name>
        <name evidence="7" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="471"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="616"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="645"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="673" mass="72778" checksum="EC31F35D2D32E7A6" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP7</accession>
    <name>V6DWP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7633" checksum="742F1C679D11F333" modified="2014-02-19" version="1">MVSHVLWWRGDDSAGSNLLRKLLSFFILSSGRHRHNDCAITVVTARKADYSVVQREKPPDAGRPVAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP8</accession>
    <name>V6DWP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="140" mass="15690" checksum="1D4774AFE07A71DB" modified="2014-02-19" version="1">MISTLIRPEYPRLWIVLFLLGALIEWLVTATVYVEMSQIESNIGEAKSEIDSTKKRAKTIKSEIEETQSEVMETKSEVEGIQEDTFSFISDSQGMGGRSLEERVSNLEDEVGVGRGGGRGSLSRRVSDLEDRIDDIQRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWP9</accession>
    <name>V6DWP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C470_11227</name>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078140.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69279at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="196" mass="20887" checksum="9EFA1A39526CF428" modified="2014-02-19" version="1">MDHTRRDALAGSALALSLATAGCLDFAAGEGPQGPEGTPATLTCEDENFVRLDQPFEGDVEETVVEAGETTFELSSEGNSETYGQSLRLVLRNTGDGPATALGRHAYSIQRETETGWIEIRGSTTGETVELPRSEEALDSSGVYNWSIDLDEQAIASAVPDVELTVCPELGPGTYRFVYWGLVDGPPIGVEFELVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ0</accession>
    <name>V6DWQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_02238</name>
        <name evidence="3" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077346.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="22281at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="15"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="433" mass="45795" checksum="289E00ADC27BAAFC" modified="2014-02-19" version="1">MAQFGNSVRLLGDREFAALAGTAFARSQAYSTILIALALYADLFGTTGFVEGLFGTAFAVVQLVIVLPLGRWVDTGNAKRWLLGGFLVNVAVFVGFALVDSSVHVILVRMVQGLGASVLWITGATVIGEISPDDERGRWLGSYNQFASFSSLAGDLVGGYLLYAYGFSETYLVLTLVTLAAFALVYAFLRDNPGGRKDPEDAGGIETFRSLLGLPMLRALVFFRFTFSVGKMAVIIFLPIYARTSFGISAFAIGWIMAGGKATKALTQGFVGDLTDRYERTYLFVAVGALLYGVGTATIPLAAYFEGTVSPVTVSYLGDSQTLGGAFFALFGAYSLLGIADSIRLPASMSLFVSEGEAYDSVASAMSLRSVSWKVGQVVGPVLVGTTMDGTSTETGFLLAAAFIAFATTGFAWQARNAHRAARDPGPAVPGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ1</accession>
    <name>V6DWQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_05818</name>
        <name evidence="3" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="279" mass="30004" checksum="083637F2B3798A84" modified="2014-02-19" version="1">MEALFLDVVRLHETWMEIVFPRQLDPSAVLGKWKPESAVQSIGYYLWAVLGAPLVAVAYPLLLVGFATRYYAAKLDSAVTRIGIAGAVLVSAVAWGTLTVITHLQLPFDAVIAVGAASTVAVVSAALAAGFSKLGGRFVSVLLAYPFAMTALFLPPVVAALVTPTLEELILPPSYELARWILDTFLSVGGINETLRGAFDLETFGEQWGTTRVGVRPDVARHFGAARLVPRAARRAREPDPTDVGRLSRSASRTRSSPRPAPSGTVWPTVRGRRQSTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ2</accession>
    <name>V6DWQ2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Taxis protein CheF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_09721</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in taxis signal transduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078144.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38718at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007381">
        <property type="entry name" value="CheF1/F2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42201">
        <property type="entry name" value="PTHR42201"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04283">
        <property type="entry name" value="CheF-arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026802">
        <property type="entry name" value="UCP026802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR026802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="290" mass="32476" checksum="4D8806BF7013B338" modified="2014-02-19" version="1">MSQEDSEYKITDTQAKFAVAVREGRKVSDVSWTPGRVLLSNRRLILAGNDGKRTVPLSKLERLGGRHDANQTVARVSNYVSFDLGEQVLLVAASDHESFERDVYRALLDQKTVMAKHPAIEGGVVQDTEWEQARVKIDENGLNAALERGVFVKFDLDDISGLDAAKRTVNGDKKPVIEVSHTDDEGTSIETHVAGDPNRMRFVESWLRKGEERSSTNVDLSSRDREVLMALYSGVSPFEIPSFLGMDVDDVEETFERLVELEVVEEVRIRREVALNSRGRNIASEAMNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ3</accession>
    <name>V6DWQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13607</name>
        <name evidence="2" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078163.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90239at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043829">
        <property type="entry name" value="DUF5806"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19122">
        <property type="entry name" value="DUF5806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="243" mass="26400" checksum="6CA561FD26659154" modified="2014-02-19" version="1">MSDDTGPAADSADETGGGADVPGGETGDKADAPGDEADVPGGESDETGATNASDGTDETGATNASDDVPRDVRKYERFKKMDGARYERVNEFLRDRTYITAREWAIARLCADFRTETGVEMTKIGENLPELVPFMTDTYTPQAVNQARYSFEEKVTKAGATFLYGAMSGFFTAEDLDEMMYEVTEVAKFLLEVEGVDLAVADELEAEDRISEVMRDVRASSADLRGEEVRCPECGHVHEPTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ4</accession>
    <name>V6DWQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5797" checksum="BD6B0FCC8E5BF2EC" modified="2014-02-19" version="1">MWVDSVTDPSTSTHTIDVHGKEQAVDSVYQKINQLFQPHSQVSPLIFTPVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ5</accession>
    <name>V6DWQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_00580</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077351.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="28717at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="465" mass="50279" checksum="C4E93EA731D290F6" modified="2014-02-19" version="1">MDRRALLSAAGASLVPLSGCVGDDLGVAPSTNGTDGGPTGTDGGQSGDGSTASLDVELRTVPHVVTAYEPSPSRGVDPEHVVPEAEVPAALRDPLDAALDGGFETDDPDNALLSAVDEFRVYDRGELKPYVELDGTRYVFEHAMPTFTAELADEEADEYDEDRVFRESRERDDIDSAAVETFVDALTAYGPNVARGEYRRCDRPEAVAEFLDEYDYLEDGRGLSRIETAVENAEPPHAITARELTEGDMWDRPVVDESELDGTVVTFFERALASDHRKPALPGDDRSQLFAAEVPDAYGDLAAGYDEPPYYRIDGTVYDVRVGESMYDRVPVSVSVAASEDAAREFTLSVAPAPERADGEAEGPYTFTSRGALPSALWVFDDGKRRSLDIAETEGIEGPRPRRSDGEALESLTASDEMVATYAVPESLPADTYVSRGTFRVSWGVPGQTPDEYGAYPFELAIAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ6</accession>
    <name>V6DWQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_00735</name>
        <name evidence="2" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077339.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104582at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="188" mass="20829" checksum="9B03369E7E42D6CE" modified="2014-02-19" version="1">MDELVVSTEVYADPEEVYAFLLDFPQYANYSEYLREVTTVSGDGGPGTQYALTFAWWKISYTARSEVTGVEPPERIDWEITKDIDAGGCWRVTPPETGDGVDDPEDPSDADPNGNAPCEVALEVEFDPGSASSDALDLPRLVSFDWVLKKAIPLIRSEAERVVERAVQDLEGSTRDVDLDVYVDSNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ7</accession>
    <name>V6DWQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C491_21341</name>
        <name evidence="1" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11620" checksum="D2AA96CC7AA2BE43" modified="2014-02-19" version="1">MATTCALCRRVVPDGRIDDPQVVQEHHLRPEERATSPTVMLCRPCHDQVHALLTNAELRETYDTVEALRSADRLRGYLDWIRGTEKLDIDITTSGHVRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ8</accession>
    <name>V6DWQ8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP cyclohydrolase MptA</fullName>
            <ecNumber evidence="3">3.5.4.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GTP cyclohydrolase IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">mptA</name>
        <name evidence="5" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25860"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58854"/>
            <dbReference type="EC" id="3.5.4.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; 5,6,7,8-tetrahydromethanopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.39" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078149.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109805at2157"/>
    <dbReference type="UniPathway" id="UPA00065"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003933">
        <property type="term" value="F:GTP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01527_A">
        <property type="entry name" value="GTP_cyclohydrol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003801">
        <property type="entry name" value="GTP_cyclohydrolase_FolE2/MptA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022840">
        <property type="entry name" value="GTP_cyclohydrolase_MptA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36445">
        <property type="entry name" value="PTHR36445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02649">
        <property type="entry name" value="GCHY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00294">
        <property type="entry name" value="TIGR00294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="site" description="May be catalytically important" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="308" mass="33692" checksum="F01ABE99FB09631A" modified="2014-02-19" version="1">MSHQLPDVQASAPDVTVGLSQVGVTGVEKLVKLARGDKRPIVLMAEFEVFVDLPSGRKGIDMSRNLATVDEILEDITREEAYRVEDVCGDAAERLLEKHDYTTTAEVSMSAELVTREDTPASGIETQSTATIVASATATEDGTREEIGAEVTGMTVCPCSQGMSESRARDKLAELGVDEETTEEFLEAVPQPGHSQRGHATLTITTDGHPDVDLRDVIDVARDSMSARIYNMAKRPDEDHMTYEAHADAKFVEDCVRALAEGTVEEFPHLPDDAVVHMKQSNDESIHQHNAHAEREVKLGDLRDELGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWQ9</accession>
    <name>V6DWQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5024" checksum="DE9E7511206BC735" modified="2014-02-19" version="1">MSHGRTERASGDKTRGEIGETTTGRFGSETYPSGSEIDRLFRHGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS0</accession>
    <name>V6DWS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_05421</name>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007171">
        <property type="entry name" value="DUF371"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023131">
        <property type="entry name" value="Mth639-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40696">
        <property type="entry name" value="PTHR40696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04027">
        <property type="entry name" value="DUF371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="175" mass="19367" checksum="E116AACF1C2BB574" modified="2014-02-19" version="1">MFRRRRADTYERRSGGRRRQCGFGLRRPLVEVVRAVGHENVTAEHASTVELTTDDWLTPAGDCIVGVEADRTPRDFGPEFREACRDASATIEATFVVDDGDETHRETLTGRGDPDLALVDDRSMVGRTSDYTDDERTIFVEGEGAAADLDRDLVAALADGADLRLRLKVTPARSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS1</accession>
    <name>V6DWS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_06900</name>
        <name evidence="3" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5268" checksum="16362AFDE3EBA6EE" modified="2014-02-19" version="1">MVDGGERVVEAGDTYVIPGGEPHAAANRGDEPVVGYDIFSPPRANPDWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS2</accession>
    <name>V6DWS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7926" checksum="815A5F05678E44F6" modified="2014-02-19" version="1">MDIAAAAPLIRHDVIPISRSERCEYTIDATIHQDDERVTTEHSVSFSPSDEQQTLVITVTAPSDVSITTETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS3</accession>
    <name>V6DWS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C435_21090</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11466" checksum="EE11C3E07F049C0C" modified="2014-02-19" version="1">MMLAYNEDDNEIILVPLEQRFDRRDVYNYQPGGMITGRKFFKEYGIERDETVRYHSEWDEDIGGDHVDGGFRVDLDQDGEVVNTDASKADSTPVESEAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS4</accession>
    <name>V6DWS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_09466</name>
        <name evidence="8" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.36" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078175.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64935at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="25"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="272" mass="29187" checksum="4770A14DD690C83D" modified="2014-02-19" version="1">MAGVNENGAADEEETGSLPPADASVALDAVGKTYAGDGDGDPVRALDDVSFSVADGEFVCLVGPSGCGKTTLFRIVAGLTEATDGRVLLDGTEVTGPTTDMGVVFQEYHLFPWLTVAENVGFGLERSDRSPDERERRVDEMLELVGLTEFRDAYPKSLSGGMKQRVAIARALAVDPNLLLMDEPFGAVDAQTREMLQRELLDVWESTGKTVLFVTHDVAEAVTLADRIVVMAADPGRVREVVDVDVERPRERGDAAFAEYVGRVRELIGAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS5</accession>
    <name>V6DWS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_02113</name>
        <name evidence="1" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077362.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128088at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7342" checksum="CFE82C5AEAAA3AC3" modified="2014-02-19" version="1">MPDPSSLRDSTQIVLPRGALEGHRECLEDRFTVTIIEMPERYRIIGSPVEIKAASDYLTRNGVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS6</accession>
    <name>V6DWS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halar_0286</name>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="8641" checksum="11721291A7FBE129" modified="2014-02-19" version="1">MSGVTLIVAGLLVWGVEHRRKRTVGIGLGIGFTGVVGMVSAAVDAGFDPIPLAATLVGFGIADYLLAPAYAKLRGAGEEASEADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS7</accession>
    <name>V6DWS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_13617</name>
        <name evidence="3" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="100"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="19946" checksum="0042D2392263E622" modified="2014-02-19" version="1">MSDRGYPDAVADEFPPPPTTFTDREDREIEVRPYEGDDEAREALVEMYDSFDPADRAQGIPPGGEERIREWLEAILPGDCYNVIXXXXXXXGDGDASGESDGVSIAVTHGTSDLVVNALVDCGDYDYAFHGHTHAHGVEERDGTVRVNPGGLPIPVEGADDAFRVATLDTAESGVDAVTHHVLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS8</accession>
    <name>V6DWS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4531" checksum="BF06CD3091302190" modified="2014-02-19" version="1">MDATTIGKLQHQIDSPTRRTTDGEHSCTEGETSTRTVIRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWS9</accession>
    <name>V6DWS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13712</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078191.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122584at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7933" checksum="F6B6D320362FDDA3" modified="2014-02-19" version="1">MTESNGSDRARSQPVVVQEDTHQNEIPENIDSELYSADSPSNSFHEFRMEPGDDLVEALRENGHTVVFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX10</accession>
    <name>V6DX10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09948</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077426.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86304at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="17396" checksum="F9B6C1980B1D86F2" modified="2014-02-19" version="1">MSLDVDPPDPPELAAVDPNEYEDAEVSGGEYRRDELEAFLREGAWEEAFDEWAAGSDMDEEDWRIALDLELVSRFDFFWDDFADRVGYHAPGLPEDWKERDLHPDLDSWGTVSAINAGLTELGQIVCETLKTEYIDWEADFDAPDDLPDFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX11</accession>
    <name>V6DX11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
            <ecNumber evidence="5">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_02656</name>
        <name evidence="5" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="4">
        <location>
            <begin position="131"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="510" mass="54308" checksum="03D876118B91BAE6" modified="2014-02-19" version="1">MMLEALMAVAFAGALTVFLAPDEWAGRLAFAISLIPFVGSLYLWSGFEAGGNALLGGEIAYATQIEWLEVGGRSVSWFVGLDGISLPLFVLTTFLVPLAILSAWTPVDTRQSQFYGLMLFMEANLLGVFAALDFFLWFVFWEAVLVPMYFLIGIWGGPRRKYAAIKFFVYTNAASLLMFIGFMGLVFALGDSVSSFALPEIAQAVAAGNLGEWLGVAPDTVALFAFVAMFLGFAVKVPIVPFHTWLPDAHVQAPTPASVLLAGVLLKMGTYALLRFNFTMLPEQASMLAVPIAAIAVVSVIYGAMLALAQKDLKRIVAYSSVSSMGYVILGLIAFTEYGVGGATFQMVAHGLISGLMFMAVGVIYNTTHTRMVGDMAGMADRMPVTVGILVAGAFGYMGLPLMAGFAGEFFIFVGSLSAPALPYAPVFTALAMFGIVIVAGYLLSAMQSTLFGPFELETDYEVGPAAFHDVAPLAVLLVAIIVLGVAPDIFFEMIRDAAVPVVEGVTING</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX12</accession>
    <name>V6DX12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein</fullName>
            <ecNumber evidence="6">1.2.7.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_02591</name>
        <name evidence="6" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.3" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077428.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41678at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047553">
        <property type="term" value="F:2-oxoglutarate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="4">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="5">
        <location>
            <begin position="210"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="432"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="585" mass="64008" checksum="0514B4C853855F9D" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX13</accession>
    <name>V6DX13_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="8">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpA</name>
        <name evidence="10" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078249.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65368at2157"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="281" mass="29723" checksum="D0B9A271311AADB7" modified="2014-02-19" version="1">MANADALDAAFADGPAYVPYLVVGDPDYESSKAYVEALDRGGADVIELGLPFSEPIAEGSTIQEALVRSLDAGMTPERFFAFAEELEVDAALVCMTYYNLIYQYGEGEGPRPFVERAAAAGIQGLVVPDLPAEEADPLREACDEFGLDLIFIVAPTTRGDRLDRMMANVSGYVYVQARLGTTGARDDVSDQTTASLDRLGEYDVPKAVGFGISTGDHAERIVAGGADGIIVGSALVDVVAEGVAEDSSTAEVADRLEALSRELKSGAERGHRSRTETVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX14</accession>
    <name>V6DX14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_00815</name>
        <name evidence="1" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004595838.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7399419"/>
    <dbReference type="OrthoDB" id="109038at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11776" checksum="A13D0254C6AB12BD" modified="2014-02-19" version="1">MIDRLEKEVDMLERHLQVLRMVIENEPIGIVKMSNETGYPHHKVRYSLRVLEEENLIEPSSQGAITTERTHEFVDELDEKLDETVEKLGSMRIDDAAELEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX15</accession>
    <name>V6DX15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH-quinone oxidoreductase, chain I</fullName>
            <ecNumber evidence="3">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10053</name>
        <name evidence="3" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629674.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="GeneID" id="65212280"/>
    <dbReference type="OrthoDB" id="108931at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="17674" checksum="47151C965F83D4C4" modified="2014-02-19" version="1">MIGLMKSMATTMKHALDGKTFTVEYPEDAPEVSPRFRGVHKFSQERCIWCRQCENVCPNDTIQIVQDDQRNGEQYNLHIGQCIYCRLCEEVCPVDAILLTQNFEFTADTKDDFVFNKEQLKNVPWYKGIDPLESRNPDRGAWIGEGDGEVDYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX16</accession>
    <name>V6DX16_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L24e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rpl24e</name>
        <name evidence="3" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077816.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125162at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00773">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023438">
        <property type="entry name" value="Ribosomal_L24e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_L24e-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_L24e_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="7237" checksum="56D9D7711E59CD9A" modified="2014-02-19" version="1">MVETRTCDYTGEEIEPGTGTMFVKKDGQILHFVDSKAEKNYLLGREARDLEWTEEGRRQGGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX17</accession>
    <name>V6DX17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6467" checksum="806D590E4E823A5B" modified="2014-02-19" version="1">MFRLAETARPENGRPPRTFPKPVTSSFDAAAHHDRRNVSLLKDNAFLPLVGTTWYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX18</accession>
    <name>V6DX18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4152" checksum="7B027687497D1F10" modified="2014-02-19" version="1">MDSFGYCGETVSEAPVAQLYVIAIYKRAIDTKTAEAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX19</accession>
    <name>V6DX19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6280" checksum="53BE5DBD1E077324" modified="2014-02-19" version="1">MIPPTHGVFTASRVERDGGDRHATTISVKERETARSVEITRVRVVFYSLLRPPEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX20</accession>
    <name>V6DX20_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="2">N5-CAIR mutase</shortName>
            <ecNumber evidence="2">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C470_05136</name>
        <name evidence="2" type="synonym">purE</name>
        <name evidence="4" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077447.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104083at2157"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="3">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="202" mass="21255" checksum="FA33029D77758F4B" modified="2014-02-19" version="1">MTTVDDLIDRIESEAQLDADPATTPDVGIIMGSDSDLPVMADAYDALDDLGFAEQTDFDDAPDARFTYESYVVSAHRTPELMYAYGETATDRGLDVIIAGAGGKSADLPNMTASIAYPVPVIGVPVQEKSVDSVIGMPTGAPIVAVDAGKSYNAALSAAQVLAREHDVVAERLVELHDEQKAGVADVSAALHDLGVDGFRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX21</accession>
    <name>V6DX21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_16751</name>
        <name evidence="3" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077821.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45411at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014651">
        <property type="entry name" value="UCP036983_2CBS_MJ1404"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036983">
        <property type="entry name" value="UCP_2CBS_MJ1404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="66"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="128"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="206"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="379" mass="41792" checksum="4050040CB11951DD" modified="2014-02-19" version="1">MNIFDIAVSEYVEVDVDERLAKVRSIFERENPKGIVVVEDGEYAGVVGEKQLMRSRMEDDTKVSAVMKPAPSVDRHEDVRETARLLVEGDVKIAPVYEGEKLYGIITVDQILEAVIDSLDAITVGQIATEDVIGIGETESVGRAINRLRENGVSRLPVLDDDGDLVGVVTTNDIVEFVVRDHERQGSGDRAGDIDRMLDIPVYDIMSSPVVTATNDETAQAVVERMFDNEVSGLVVTPAGADTVAGMVTKTDVLRALTFTEEDSMDVQITNVDLLEGTSREHIRESIEQVVDKYADMHVIHAHVRLHAHKEKLRGTPLIQCQIRLRTNEGQVGGSGEGYGAEHAFHVALDKLERNVLEIKGVNADEEYRGQLLRKLGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX22</accession>
    <name>V6DX22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="8757" checksum="F4D4B83D6B01C07C" modified="2014-02-19" version="1">MSPVCSGSSPSTRTSVRSPTAEVTMICGSSPREYKSSYRSCGLNVSTGLRRQNPAAVVVGYPRTTADERPRNPFGATRATFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX23</accession>
    <name>V6DX23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10804</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078287.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125184at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8509" checksum="8A3BA3EB7F41AA98" modified="2014-02-19" version="1">MSDTTEETAVEVVEEVSSDGLGPAVFAAVGSVALALYFYYVRGDKQRGQFVGLWPVTILGLASYFKLEEIQEALSASDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX24</accession>
    <name>V6DX24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na+/solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C468_15037</name>
        <name evidence="9" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078259.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25355at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019899">
        <property type="entry name" value="Na/solute_symporter_VC_2705"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03648">
        <property type="entry name" value="Na_symport_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="537"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="586" mass="62203" checksum="9AAE5B365F1A5B30" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX25</accession>
    <name>V6DX25_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="23600" checksum="60206C104E4010DB" modified="2014-02-19" version="1">MAVQLGGGLERLHLVGADRVREEIRDVGVVDHRRQHLRVAVREDVTVVARVAEPADALAHVVEHLQLVVHREDLVALRGREVDAVRRQRVRQRVPVHLEKGLVGVDRVRDERVRQRPRPPQPRHRLGVGNAVRERRLGGLHVHERAVRVEGYGRHALGVERHMRTNSRRRNKRRDDGRTDAGDRGTDANTGRADRGFISVERHSSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX26</accession>
    <name>V6DX26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10043</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077442.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="119" mass="11950" checksum="742877C5B460DDC7" modified="2014-02-19" version="1">MSNDESRGSKIAPAIAVGALFAVLAATVNAAAFDAEFAGFPADASVVHNIGYSLFNLGGYDIATIGAEGFLAAFLIAAVALDVAVDGAVYLAKREEDGSIVSAVGQALTDGGRDGGERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX27</accession>
    <name>V6DX27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_02117</name>
        <name evidence="8" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077827.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="11037at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="451" mass="47365" checksum="5B1324AB4CB2AE29" modified="2014-02-19" version="1">MARETWATRAGFILAAVGSAVGLGNIWRFPFITGQYGGSSFLITYLAFVALIGFPAILVEFVIGRRTDRNPVGALRELGSGAWSYAGWLFVVTGFIILSYYSVVAGWFLRYTLIGITEGFTLTDPSEAEALFGTVSTGLDTLLFHAVFMLLVIGIIAAGVRRGIELSVKVMVPAILVLLLGLAAYGFTLDGASAAYAYYLSPDFGTIAANWTEILPAAAGQAFFTLSLGMGVMITYASYLGEDRNLAADAGIIATLDTLVAVLVGFVVFPILFSVGIEPGTGGPGAIFVSLTSAFAGIPGGRILGVVFFGMVGIAALSSAISILEVLVSYLIDEVGVARVPASAALGVAVFLLGVPVTVDLIFLDLYDLLADGILLVLGSLLLALFVGWVIPDIARDELRQGLDGLGGLGDAWIWAVRIPIVIVVIVSLYLGIVDYANFLTGGFAEWLAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX28</accession>
    <name>V6DX28_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="6">PTH</shortName>
            <ecNumber evidence="6">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pth2</name>
        <name evidence="6" type="synonym">pth</name>
        <name evidence="7" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008581783.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115947at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00628">
        <property type="entry name" value="Pept_tRNA_hydro_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034759">
        <property type="entry name" value="Pept_tRNA_hydro_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PTHR12649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="11937" checksum="7E986F0652DD3EB0" modified="2014-02-19" version="1">MKQAIVARTDIGMGEGKLAAQVAHASLSAYQDAGRRARKKWQGEGQKKVVLKGDSESQLFELADKADKEGLPYAIVRDAGHTQLDPGTVTALAVGPARDDSVDRVTGDLSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX29</accession>
    <name>V6DX29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3828" checksum="551064D4BBDDB2A7" modified="2014-02-19" version="1">MRRAPGQGDETPSDADIHFHLAAGAFLGASVEGTDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX40</accession>
    <name>V6DX40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_15914</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078298.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116265at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007254">
        <property type="entry name" value="DUF373"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38815">
        <property type="entry name" value="PTHR38815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04123">
        <property type="entry name" value="DUF373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="378" mass="40119" checksum="F775D3CE387C6474" modified="2014-02-19" version="1">MTTLVICVDRSGAIGRATNVPMPVAGWEAVRSLVTDAGLDDPEDASVNCLLESLRVARDLRDEREESVVAVVSAESDTAVGADRSIAAQLDDLVERYDPRAAIVVVDSAEDERVLPVVESRVPVDSVDRVVVRQARDIESTYYLLKQFLADEQLRSTVLVPIGVALLLLPVLFARFSAGEALAGVAGLLGAALLYKGLAIDRRVAGMPERVREALYAGQVSVVTYVVAGGLALVGGFFGVLAASELNPGSPRLVEVVEFAFAAVPWFAVAGVTAAVGRLLDELIRDEGIRTPYLNLPFVIAAVALVVRGFAGYFLAQEAVRDPLSVYGMTMTPVQQLAAFIVGGIVVSLVGVKVASDVGTETLEDVIDAEREADGRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX41</accession>
    <name>V6DX41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13671" checksum="252D53C1F34B7681" modified="2014-02-19" version="1">MRLRPRRPRTNSPRQDETIDNGDERQTTDRRKRGRRRSAERDRIRNEAECGTNGTGGSGKGWAKGERRGGGRRAGGGRTADPQAVVGDAARVVGTGARIVNAELQREKRRTSATERTCLTGINM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX42</accession>
    <name>V6DX42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligopeptide/dipeptide ABC transporter ATPase</fullName>
            <ecNumber evidence="8">3.6.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_02891</name>
        <name evidence="8" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.24" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077459.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43111at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="358" mass="39190" checksum="0412961DB442047B" modified="2014-02-19" version="1">MALLEVKDLTVRFYTQEGVVTAVDDLSFRIEKGEKFGVVGESGAGKSVTALSVLRLIDSPGRIESGEILFKGEDLLEMSESEIRSIRGNEVSMIFQDAQTALNPVYTVGGQIAEAIEHHLDYTSKEAKARTIQLLDRVGIPEAEERFSDYPHEFSGGMQQRAIIAMALSCDPDLIVADEPTTALDVTIEAQILDELRELADEFDTAIQLITHDLGVIAEVCDRVMVMYAGKPVEKAPVEELYYDPKHPYTVGLMSSIPRVSDKRERLQTIPGVMPDLVQLPSGCSFHPRCPFAEEKCTRKEPPLTDVESGAEATLDTEHAAACLEYTEGLSQGLTYSVETTGPADGAAAQYVEGDRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX43</accession>
    <name>V6DX43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="133" mass="14299" checksum="6F47D501ECC0C008" modified="2014-02-19" version="1">MALDGVGRRLRLRAAVLQPADEDVDLAVGVQREERVGTGEPGEVQLVGVVLRGVEQVAVGVQIGERLVEPRSVHASHCSGDAQSGCPRGTASGSESATAPEPRPRRRRETPIYYTPARDASVPLSIFFRPPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX44</accession>
    <name>V6DX44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4801" checksum="7404D7C506216EA1" modified="2014-02-19" version="1">MRAIRALKFRFSRLAATATPSACPPYKSRRRDRRPCDSFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX45</accession>
    <name>V6DX45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate uptake regulator, PhoU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10219</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077454.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37632at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="343" mass="38164" checksum="588DA2D524AD2C99" modified="2014-02-19" version="1">METRKVQRLGPSTLAMTLPAEWAQEHGVNKGDEVSLRMGGKGTLTVLPESVSSEESEAVINADGLDARSLERAIVAQYVLGRRVIHVRSEGTLDSEHINAVYKAETQLMGLGVIEETPEDISIRCSVDPEDFTLDNLLERLENTGSTMRGEAVKALAHGNPDLAQRALNRERQANKIFVLLLRLIFTAYQNPNLARAVGLEEGFPLIGYRSVAKNLELTADNAEDIAEIVMEADGHTLDVDSATMRQIREFTDQVDELTALAVRAVVERDYDLTVECRDLFSRLEDREQEILDELPNDLDNETLLMTREVLVSLQHTAEYAMRNAEIAANLALNEESDHVEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX46</accession>
    <name>V6DX46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="7181" checksum="DF5EAF214BA74DBB" modified="2014-02-19" version="1">MESDALCRLGIPHPTTDYYNMLRYAGGWRLERIIGHSLIYTTKYVRNYKSWNDNPTRENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX47</accession>
    <name>V6DX47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Imidazole glycerol phosphate synthase subunit HisF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisF</name>
        <name evidence="1" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4349" checksum="062F62D4314FE6D3" modified="2014-02-19" version="1">MFTEANADAGLAASIFHFGDYSIEETKAYLDERGVPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX48</accession>
    <name>V6DX48_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Thymidylate synthase</fullName>
            <shortName evidence="4">TS</shortName>
            <shortName evidence="4">TSase</shortName>
            <ecNumber evidence="1 4">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">thyA</name>
        <name evidence="6" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 4"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077842.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32556at2157"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="5">
        <location>
            <begin position="2"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="196"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="237"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="38740" checksum="EEC226C0C94BD1BC" modified="2014-02-19" version="1">MQQYLDLVDDALSTGTYKPNRTGVDTIATFSGQYTIDLAEGFPLLTTKKMDGYRWNSLIHEVLWYLSGEEHIRNLREETKIWDAWADDEGKLDTAYGRFWRRYPVPADDAALPGETWPDDAHRWVTVEEADDGTERRTFDQIGYVLDTLAENPHSRRMVVDAWHPANAAVSTLPPCHYTFVVNVQDGRLNLHLTQRSGDIALGVPFNIAAYALLANALAQRTGFEVGEFGHTVVDAHVYCGRGDRGKWYANNLKYVQERLANVESKEEYLDVKSWVERTAPDEPNGQEGYDHVPGLLEQLSRTPRDRPRIEIADAPLDELTYDDVELVDYESADGISFAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0A3</accession>
    <name>V6E0A3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="140" mass="15238" checksum="F6022A13BEB791BA" modified="2014-02-19" version="1">MYRRSLLVALTPALAGCSLTPTGPLTESYPTSAPNVFASFDWDPDRSVLIVTFDRGNRLTAENTGRLSVITPDPEGVETVWVDRDDTDTASEFPLTPGATLHHEISAPATTHVVWEGPEQQNSQAVGNWRPEMTRSEGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0A5</accession>
    <name>V6E0A5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc-containing ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">C467_10046</name>
        <name evidence="11" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="7 8">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7 8">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078370.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000026.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111853at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009157">
        <property type="entry name" value="Fd_Zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000068">
        <property type="entry name" value="Zn_Fdx_Sulfol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000068-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK41025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11938" checksum="96AACEF29DC88944" modified="2014-02-19" version="1">MAIDPNFETNRERAGEEDGVAVWGPVEPPEKQGIRGTHVAVDFDICLADGACLEDCPVDVFEWVDTPGHPESERKANPADEDQCIDCMLCVDVCPVDAIDVDPGRENRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0B8</accession>
    <name>V6E0B8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proline dehydrogenase</fullName>
            <ecNumber evidence="6">1.5.99.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C473_13096</name>
        <name evidence="6" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.99.8" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078389.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="56193at2157"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008219">
        <property type="entry name" value="PRODH_bac_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PTHR13914"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000196">
        <property type="entry name" value="Pro_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="5">
        <location>
            <begin position="19"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="279" mass="31106" checksum="F333E4BFF622E3AC" modified="2014-02-19" version="1">MILPIARRFVAGESVPVALDHARAANEDGVAVILNLLGEHYDDPADARGDTDAYLDLIDDIADSGLDACVSVKPSQIGMDVSADLFEEHYREIVARADELDAFVWCDMEDADTTDATLDAFESIAADYPWSVGQCIQSNLKRTADDLDRLVDVPGKIRLVKGAYDEPSSIAYTDKADVDEAYRDDLRRLFEGRDRGVAVGSHDPEMISLADRLARDHGTEYEVQMLMGVREDAQRDLAAQGVDVYQYAPYGDKWLSYFYRRVRERKENLTFAARAVLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0C2</accession>
    <name>V6E0C2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C472_08534</name>
        <name evidence="10" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026371">
        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0701">S-layer</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK41048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="16907" checksum="21DD614C2382F4BF" modified="2014-02-19" version="1">MFVGNGSEPVDVGTLMVETTESDDGVEDAVEAVTDATVEDADVLIEPRATVVTVPVDLDDGTPVEVRLRSAGNASTEFIKTREATVTDGEATATFDASVTEPGDRATLTVRGDGDADESVTRDVLVVDDVDAPGSGDTGDEAPGFGPVVAALALLCAALVARIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0C4</accession>
    <name>V6E0C4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease R</fullName>
            <ecNumber evidence="4">3.1.13.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_08649</name>
        <name evidence="4" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078386.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21042at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="70"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="433" mass="49906" checksum="C17A1E0A072D7A22" modified="2014-02-19" version="1">MSDDEPKQGSAEDQGPVTITPELADRLAEKREELFEEFEIRDEFPSEVLREAEARTEDVYEEIEDEIDEREDLRDLTTWTTDPVDAQDFDDAISIEREEDAYRLWVHIADVTHYVTPDTAMWEEAVERANTVYLPDYTIHMLPPVLAETVCSLVPNEDRLAHTVEMEIDSETLSFEDIDIYKSVINSDERLTYSECENRLEDPDLPLSEENQLAFELADRMHEQRKADGSLVLNPRRDRAHTIIEESMLKANKAVTHTLMWDRGVEAMYRVHPQPTPDQWNEALKEIQELNGVSIPGDAWGDDPRKAVNAALEESPERQLNKIQRAVLKVMPRAKYMNDPFGGHHALNFDIYGHFTSPIRRLSDTINHWIVHENDVPENLVELCDHASDKQKDGETAERLYKQFLQEQGLDPHAVNNRGVEVVEDPEEAKHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE6</accession>
    <name>V6DSE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gap</name>
        <name evidence="3" type="ORF">BN903_155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.59" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043891">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_C" evidence="2">
        <location>
            <begin position="10"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20229" checksum="12A99FD53FFAAFAB" modified="2014-02-19" version="1">MRRGGDPSETDRGPINDILPDPATVPSHHGPDVNEILPDVAVDTAALKAPVTGMHTHSVNVTLETEPDENDVRDLLAGEDRIFLVPAAAGIDGAGALKEYAADAGRPRGDLWENCVWEESISVTGRDLYLFQNVHQEADVVPENVDAIRAMATDVGRAESMARTNETLGVGLDSRLGDGELARAELAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE7</accession>
    <name>V6DSE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Hmuk_0943</name>
        <name evidence="6" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076832.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42250at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="87"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="34843" checksum="BB3597AB272FEE51" modified="2014-02-19" version="1">MGTAEEYAETPADSRLERGMNYLRHNSRAYLLIAPAAIFLLSIVGYPIIETFRLSLYESPADSSIETYVGLQHYVEILGSDIFYQLLWQTGRWVVIGVAGKTLLGLLIAVHLKGDIKGRKFFRTAFLIPWGIPYAISAVVFRWIEHPQYGYINAVLLKLGITDQAIGILGNPDIAWLGVVVADIWIGTPFMAIIFLAGLQSIPQELYEAAAIDGAERWHQFRYITLPQLKSVILIATLLSTIWTFVSFDTIWTMTRGGPINTTSTLVIWIYKVGLENGNLGRGAAFSVIGFLFLLVFAVVYLRVYTRGGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE8</accession>
    <name>V6DSE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Natpe_0598</name>
        <name evidence="3" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025959">
        <property type="entry name" value="Winged_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13592">
        <property type="entry name" value="HTH_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_33" evidence="2">
        <location>
            <begin position="108"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="174" mass="20153" checksum="E4DC4EA2647150B7" modified="2014-02-19" version="1">MDHLNEIAVEELQEALDNVDENKPTQRLLAAIAYKNGVTQTELAEWYDTERKTIYNWLKRLDTDDPLEQAVTDAHRSGRKRKLSETQQQEFEQTVHESPQEIGFDAPAWTPALAQEYLEETYGVEYSVPSCRRLLKEVGLSYQKPRRSAAESDVDEQEEFYDEVKKSGGKWTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE9</accession>
    <name>V6DSE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HalDL1DRAFT_3157</name>
        <name evidence="2" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076848.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32950at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="356" mass="40229" checksum="0E6D5CAAE371495B" modified="2014-02-19" version="1">MATVNEGVEGAEPDEEGEDDVRTGSLVSQSLPHEYQEDALEFNVDSFRLDGSPLGDRGELDKDDQFLSLVDEGSWETLELEGTVTVDQDTVEEVFPFDEWEETPGRLALVTENPLAMNRDRQILTDSPFDGGTYEFTLSINRDHYRGRVKIKPFLTRTEEGGSGGSKHASKVGARVADGISWIVRLDERDDGGSLLMPIIEDFSDYDSFPDENHIHYLSLEAPRNPQLYLNREHPQVVEVLNNTGYTGGPPRLRDVLYDYIEHSVWTQLLLQTARDTSPDTGEPEYGWQEDILDIFLEDLYPNLGDDEAAIQLAEDVRSHVDIPDLVQRIERTVHQQYDIPSDTTNLIEEAIQSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF5</accession>
    <name>V6DSF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06322</name>
        <name evidence="2" type="ORF">BN903_165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="1">
        <location>
            <begin position="15"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="210" mass="22999" checksum="378DC04D10BF14AC" modified="2014-02-19" version="1">MNLPFRYTPGFVRLRELVAAGEIGDPRRVELRFRFPEWPREWQDVAWLESRAQGGPLREVGTHFLFGVQELFGPIETVSADVGYSGPDTYEDDVVGTFRADGVRGTIDLLCDHEGDEENAITVVGDEASLSLTEWYRLVRDRGREGETTLVDERGDTVADLLTEFASAVDGDGGDLVSFAEATRVQEVLDAVHASEGDRVRPGADGGGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF6</accession>
    <name>V6DSF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076842.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60161at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="37729" checksum="8DD775C02E5853C7" modified="2014-02-19" version="1">MAHECDDCGESFETLTRLRLHDCSDVQSDTFSTPTNSDRSESTDSSPTEERNAAVAELDNLLDRFSDGNVDALHYAVVEFEAALSAAVEEDSSGDTFRDVFWPYYERVSDKLDDVARVHGWPFLADIIDAHEPTEKDEFPLVTPTIANAVGRYLIRTRITDGVEAIPVKALEYLNTVAVNAPESDDVAREEVHAYGWGIGHPDHSVVDRLCARAPEDIFSVNPTVEHAFYADQYAAVDLLEQLVRDESINGTLPRVTRDDMPYRRYLLDCVYGLKTDDYWPGMPRYYDWYDEFEYAFELDETVEQRIRDIVEEMGFDADLSNDWTFRDLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSF9</accession>
    <name>V6DSF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase S9 prolyl oligopeptidase active site domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_14147</name>
        <name evidence="1" type="ORF">BN903_170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7539" checksum="4C0DB20EA1E6A13D" modified="2014-02-19" version="1">MPVSRTRISRGALDDAGFEEGVDYKYEGLGEEEHGSGDIDQKIRSLELLGDFLDRRIGAERAAVGSPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG0</accession>
    <name>V6DSG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pNG6009</name>
        <name evidence="1" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076847.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114818at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="10480" checksum="9BAAB15A1D6DE0F0" modified="2014-02-19" version="1">MTKEPIEVLDDLADQVADEFEAYRQPDEFKDVSLVIENSDEEHPTLIVHVDRENVESLADRIDEFLRERGARTERERHSDTDVRVLATVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG1</accession>
    <name>V6DSG1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C455_00072</name>
        <name evidence="2" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076860.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49107at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="10"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="396" mass="44569" checksum="C9B1DC368A9301FE" modified="2014-02-19" version="1">MDDLEFALANLRGYPFEKFAMAYLREQGYQVHESGSSGPDGGWDGQVEISGREGIAHASVQETWRRKLRSDAEKVKQLEEERGEDYDLFVFVTNQDVGGRQELDLQDEIREEYGWKLRIHHREEILGELRQNSQDLAEEFLDVDLQKDHDHIQEIEELCSDRLDKLQARDGYASELIEGPAIALHIIPNGVLSKSKNRSGDLPNPSIIFEERENYGESKGKHTISYGRGGSPGEHHAYAVLRNDGLYESASVSAFHEKYEDLWLQGFIQDGVGIGLDAAIILAARETMMDLSKMGFSGTTFAFVSLLDAGDVQLVTPDHLGSSLHRSPKTIDTDRYTTEYATLQIGSEQVIEGLEPVLDELWRQFGDDGSPNIEDGKWTRQSCKVRDGMTIEEGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG3</accession>
    <name>V6DSG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HalDL1DRAFT_3154</name>
        <name evidence="1" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076850.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50993at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="258" mass="29717" checksum="1F0B5B631F23480B" modified="2014-02-19" version="1">MTSNGGTTREEPLILHCFADYGTESEVLSDFGNVIRVGIDPKDTNESTPIKADAHIEDKEWNFPIKDDVTFDLGLFHPVCSRWAATTSISGSPDKHENMIPSARILARKFCDHYIIENVPRAPLNDPVVLNGRMFGMPIEYERAFESSFKVSQPPRERRFLTTDGPSDKAETSSFFFSERSREWWAAVKNYPPGPYPKSHLAKNAIPAPYIYYLVRLWLMVYEDEQGISKGRVDYSDYDERMDTKRKSEDNRQLDEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG4</accession>
    <name>V6DSG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Natpe_0598</name>
        <name evidence="3" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="10"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="8040" checksum="940D3825F076BCF7" modified="2014-02-19" version="1">MYRSNQEICPSLAFVTLPSYSPELNQVEIYWRQLQAGLSNHFFDSLNEFIIAINTVLDQLSIHVLSNYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG5</accession>
    <name>V6DSG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fused rhodanese domain-containing protein/hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_08820</name>
        <name evidence="1" type="ORF">BN903_175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10688" checksum="22A1D859DD5E739D" modified="2014-02-19" version="1">MLTLPDDTLIGGAHFSDAAEPAADGTYTAPIGDLVEEMDALTMDEQEFVDLILSDMPPRPANYEDIIATNLGQNAVDDEEAFTLELGPNNCAASQESLAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG6</accession>
    <name>V6DSG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076007.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9146" checksum="DBBBB5A3E3AD5EF6" modified="2014-02-19" version="1">MDDSLLTSYLAVWSKARATLEEQTTHGASLFYSSILFVASLSTLLFVLNIAELVTGTTVTLWIHGLAYLLAGCAGLVGWRYGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSG7</accession>
    <name>V6DSG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15314</name>
        <name evidence="1" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076862.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45229at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="287" mass="32956" checksum="890B6816AF7EB5F5" modified="2014-02-19" version="1">MQDALDLEELVAVLLEEHEYGDSLKPKAFHKVLYFVEQELEQERVPVQVPKFWYMYGAVVATSNSNINVDISDGGSSVTSNLDLDDIDVSEGVLRRSQEAISRALDDYYDLGLDSITNKMYEEAPYDVQRHYRQLDKQLTAAADTGQMTLDGGKNEARTRETVYDLLESFPLDEFPEYENDLYIWYRLVSAQIDSDDYDPDEAHRISETFWRLFCLELACRENSRLSHSEVAEELGVDSIEGTKEELRSFLLEQEKQKARRNARESEAAIKAAEAFVAPHLEFDVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC3</accession>
    <name>V6DTC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_01474</name>
        <name evidence="1" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5107" checksum="61E8F4E922757483" modified="2014-02-19" version="1">MDALGLAVVARHAVDDLRFLPGDVTYRDNEEIPMRMAYWSDDPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC4</accession>
    <name>V6DTC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="303" mass="32570" checksum="451CF465A2EA2537" modified="2014-02-19" version="1">MAPAAGLLDHVRERLEVVHVGVLLLVLAGGRPVDVDPTLALLLDGGDDPAVDLVARHRAGRERRELLAASVGARLHRRRTEVDGDEHLVYRVEVVAVGGDRPAQRLGVAPRLDLPDGGALDHRLEVLDARLVVDGGHRVDDRAVFGHVVGVHDRLEEALGVRDAVVVLGESGSEHEAHPVRVLDRGLLAEQHLLLAGDGVLVGRQTGQHRVALAAAPPVGDVEHRSGAAQFHADRCRFVRFVDVRGFVVAHWSLAHEAIRTMETRLIRWSAGVNGRSRRGASNPSSRRRSAATASSPTQSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC5</accession>
    <name>V6DTC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11164</name>
        <name evidence="1" type="ORF">BN903_206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077070.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76804at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="23297" checksum="640952BBE73052F8" modified="2014-02-19" version="1">MERERAVDRLETLVDRVASEPMPVPVREVWAFGDVALGLDPVDRLDVYLTKDVIMGGDADAAAEFEAEYGVKGVGTTVDAAWAEAHPDRVRTSDNGYAAPEKCLAAELVEDTEPIHLEVCNAGFEDNVRQRLKGALAREAYEEVLDPRGVCLWVDGERDGEAFERLREASLAMPTLPAALGMLGADEEAANEAADVLKRRRAEQEGASVRGDMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC6</accession>
    <name>V6DTC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="16170" checksum="987E7FFC90430F2E" modified="2014-02-19" version="1">MPPMSGLADGQPIPANTFGCQGLRLFSGGQVINLLLWSPFGLPPTTEVGGFRPCIAVNHAIVVSAILERHCRISPSCHPTGASTLSTARTAVFSYRLTSYRKSTRYRCRQKIEQLLRAACDRKGGFCVRKSSEESSIRLFCERFLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC7</accession>
    <name>V6DTC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HSB1_47180</name>
        <name evidence="8" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043760">
        <property type="entry name" value="DUF5706"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18967">
        <property type="entry name" value="DUF5706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="159" mass="17096" checksum="4A340B56FF3DB8B2" modified="2014-02-19" version="1">MTKAELAVQTRDHLNKYIAAADQKASILLTGQLAFLGLTATAAKGIVNTTGDALYWFSLGTAVAGIIAAGLAIVVIYPRTPSPDKGFIFWGNIMAHDSPEEFQAAFDNFSESDVDGEVVTQNYMLAKVADKKYGYLRWSLRATILMILLASIGGGLYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC8</accession>
    <name>V6DTC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00616</name>
        <name evidence="2" type="ORF">BN903_133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076277.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84415at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="298" mass="31442" checksum="BE02C7717A92C12E" modified="2014-02-19" version="1">MKVLVAGGTGFIGSYLCRALAEDGHAVTALSRSPEETPEGVTGVSGDVTDYDSIESAVDGHDAVVNLVALSPLFEPEGGNRMHDRIHRGGTENLVRAAADGGVERFVQLSALGADPNGDTAYIRSKGAAEGIVRESDLDWTIFRPSVVFGEGGEFVSFTKRLKGMFAPGVPLYPLPGGGKTRFQPIHVEDLVPMIAAAVADEEHVGETYEIGGPEVLTLRQVTDLVYEAEKKGITILPLPMPLAKIGLSVLGAVPGFPMGPDQYRSLKFDNTTADNDVAAFGVDAAELTTLGEHLGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC9</accession>
    <name>V6DTC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5496" checksum="4D461241C1C534B0" modified="2014-02-19" version="1">MKRATEERGSRERSSLVITKGAKRLSNDSERKSSSRLGLCRCSPSAREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD0</accession>
    <name>V6DTD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photolyase</fullName>
            <ecNumber evidence="7">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_00961</name>
        <name evidence="7" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_7" evidence="6">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="184" mass="21487" checksum="D245DF83DD2CF356" modified="2014-02-19" version="1">MTENFKAYEEGIAWRDDPEEIAAWKRGETGYPIVDAGMRQLREEAFMHNRVRMIVASFLTKDLLADWRHGYEHFRDRLADHDTANDNGGWQWAASTGTDAQPYFRIFNPMTQGERYDPDAEYIKAYVPELREVEADLIHEWHELSPTQRANAAPDYPAPIVDHSERREEALAMYKRARGEDPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD1</accession>
    <name>V6DTD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_02721</name>
        <name evidence="6" type="ORF">BN903_211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077075.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42250at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="136"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="356" mass="39950" checksum="F58D5AC27ECA7A51" modified="2014-02-19" version="1">MATSDETDERVGETYRRRARTRVRRTTRQIRRAARPGWDRVRFARQDLTAAVPTLPRVAYLFIAPFFVLFGLFLAFPVAYTLYLSFFEYQGVGEGSLFWIDLGPVYVEIPQIAQLSFVGAGNYVRLLGNDLFWQSMFNTSYILAIQVPLMIGLALALALALNASFMRFKGVFRTAIALPVSANLVAYSTVFLLLFNEQLGFLNYVLSGVGLGPVPWLTSEFWARNTIIAAVTWRWTGYNMIILLAGLQTIPQQLYEAAEIDGANRWEKFRYVTLPQLKPVLLFVVVLSTIGTFKLFAEPYVITGGGPTNSTITIVQYIYRQAFVNFNLGYASALTVVFVAVVSVFSILQIKLGGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD2</accession>
    <name>V6DTD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3508</name>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077120.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="138357at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="11445" checksum="8DC8D35E7EF1BDFA" modified="2014-02-19" version="1">MTSTNEIKNTVTFQKILDAANHRDDIRVFRREHGDEKLAEALEVTIGYLNAEMTRRMAATELGVSNYTGITITNEIEEVVRDMYREDPWLDDQLRNGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD3</accession>
    <name>V6DTD3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Probable thymidylate kinase</fullName>
            <ecNumber evidence="2 4">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">tmk</name>
        <name evidence="6" type="ORF">BN903_138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="2 4"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076279.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114844at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="5">
        <location>
            <begin position="5"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="197" mass="21724" checksum="BC0DB2D40C89D12B" modified="2014-02-19" version="1">MLITLEGLDGSGKTTVWEALHDVYPDATFTCEPTDSWYGDAVAQSMADVDADPLAELFLYTADHANHLSETIRPALADGDLVISDRYSDSRFAYQGAALARADVGIQRPMEYVQGVHAAFSREPDATVYLDLDPETAAERAGRTDKFERDGYLAAVGENYERLLEADPGRFHRVDATRPPEDVIARVESIVADLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD5</accession>
    <name>V6DTD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4814" checksum="659D13C2513843D1" modified="2014-02-19" version="1">MACRTPTATPTRCLGPSRLHKFTRRASPRGQAAPPIGAVRRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE0</accession>
    <name>V6DTE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain fatty acids transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_00996</name>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006160">
        <property type="entry name" value="SCFA_transpt_AtoE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41983">
        <property type="entry name" value="PTHR41983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02667">
        <property type="entry name" value="SCFA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="21211" checksum="CCBEA00D06690244" modified="2014-02-19" version="1">MNNSRIIGGLVALSGVAILAVQFAGQGLGAFTLNAVNFGFLFAGLLIYQRPAYYRDRFNEAAGAAAGIVLLFPFFAGIQGIMADSGLALLLAEGLLDVSTAATYPVIAWIVGSVANLFVPSGGGEWLVVGPSVLQAAEGLGVPYGQATIAYAVGDAHTNLLNPFWALPLLAITNVKAREMFGYAIAMLIALIPFLAIALYAVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE1</accession>
    <name>V6DTE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4809" checksum="64D0ACD4A1F3C66E" modified="2014-02-19" version="1">MRLAVSTHIVTGTGLLQHDWPQSTVLRECEFTACLMINFLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE2</accession>
    <name>V6DTE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C457_13694</name>
        <name evidence="8" type="ORF">BN903_148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="7">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7110" checksum="A8FF7A20E62AE550" modified="2014-02-19" version="1">MIESIPLLGGLGLSVPSLWIVFLLAAIWTYFDAQKNSGHPAILWALVVFVAPILGIILYFVIGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE4</accession>
    <name>V6DTE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="11269" checksum="5F0172C83F122F76" modified="2014-02-19" version="1">MREERKIRRKTERKIRDQEENGARESESEKRRGERETKKRGEKGGREEGEESQERKEEKGSRKGNRRIKTRGEVWTEETNHPQKSCSCHRCIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE5</accession>
    <name>V6DTE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_0241</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="547" mass="62134" checksum="A096DE4486AF3248" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE6</accession>
    <name>V6DTE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9120" checksum="933EC503AD25CF8F" modified="2014-02-19" version="1">MEPATGQVGKNGRYRGVGARYEPASVVRRTMRVSARCGSRRERRGYSTSTGCLSPAKRKYASATSDSTRTSLAFLLMSPTSGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE7</accession>
    <name>V6DTE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_14020</name>
        <name evidence="1" type="ORF">BN903_153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6029" checksum="C76FA5C993E70FC5" modified="2014-02-19" version="1">MALEKDVDCPACSETRSFYRTAAMTLHLGEKTKWRCPDCGYGYVEINGIDTLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE8</accession>
    <name>V6DTE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8214" checksum="A31ACB0A6DA96CB8" modified="2014-02-19" version="1">MVSWSVSCAAVAVETDCTIASYWTSSCSVYAAIHAVSPTTTIVESSRTLLELEFICGEKYPSRIRIQRYVRESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTE9</accession>
    <name>V6DTE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3494</name>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="9912" checksum="71F539260970F2A2" modified="2014-02-19" version="1">MNTTSTEGELAAAVEEIDAVEIDDAQFSLGVEDDPGAPQDLGRLSLYTIDKLTEVSERGIEDSVKQPVSREEGVKKVEEWVRSNEELKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF0</accession>
    <name>V6DTF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4362" checksum="675921F52D54D3E0" modified="2014-02-19" version="1">MSASMYKIYRLDVAQLSHPFRPTSTESPVLRKVRAVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF1</accession>
    <name>V6DTF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C466_12563</name>
        <name evidence="2" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076563.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="7725" checksum="34CFCBAC6992EE25" modified="2014-02-19" version="1">MTGPRQLYRRADDWARGLSRLRYALLTGVVVIASVLAVGVVLDTSTTVYAVTMGVVMTVLYYVGDVNAEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF2</accession>
    <name>V6DTF2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_14258</name>
        <name evidence="2" type="ORF">BN903_158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="228" mass="24827" checksum="FC0A5E7CC9C50088" modified="2014-02-19" version="1">MLLLVGGPFSLVYLLIAYDRSTEGAREELRSTFGDYSLSVGSIRPRWVLAGIVPLATLWVWGPSPTDIGLFYLFPLIWFLPIFAGSKGTSIRLSPAERVVERTDHTHDRTRTDDLDSVVRTRRIDFPWTTVFLLAYRGNAWYRSTPWLFVPSEKADAVESTLDAVLAASDGPDRASVPERVTLAVLGSFSLVVGLLMAVAGGEGAGGIALALLTAPFSILFLALAARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF3</accession>
    <name>V6DTF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4254" checksum="BF5A605283360644" modified="2014-02-19" version="1">MTAEYLVAITGCTYRPGHGLNSTVPCGMGRLIDDSRLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF4</accession>
    <name>V6DTF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative type I restriction enzyme specificity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">F502_06217</name>
        <name evidence="7" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="80605">
        <property type="entry name" value="S.HspAJ67ORF43P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="6">
        <location>
            <begin position="16"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="216" mass="25183" checksum="FEC602888427D960" modified="2014-02-19" version="1">MNKDLSEFTENENTQDNWQSTKLRNLLEKDESGVWGDDPEGVEGVPVLRATNFASDHIDLEDVAYRDIPESKKQNKQLQYGDIILERSGGSADQPVGRVLFFDLKGEYYPGNFLRLLRPDENKVYSHYLYYQLEYIYRRGGTVPIQSNTTNIRNLQFNSYMNQTIPLPPLDKQKEIAEALRDIEKNILQLKDLIEQYETVEFGVMQQLLREKPDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF5</accession>
    <name>V6DTF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C476_15760</name>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="DNA-dir_RNA_pol_M/15kDasu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RPOL9" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="12058" checksum="FB68040203570CED" modified="2014-02-19" version="1">MHWRQAFRIVALMKSSAINRCPQFLSTGGSRTGQYRGLMNRSVQRIPKLISTVSMNSYLKSTADWELTHIFDNCVFLLNIRFCGECGTMMYTEGDTWMCRSCGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF6</accession>
    <name>V6DTF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mandelate racemase/muconate lactonizing protein</fullName>
            <ecNumber evidence="3">4.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C496_23186</name>
        <name evidence="3" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.6" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076569.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17973at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="2">
        <location>
            <begin position="133"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="383" mass="42801" checksum="686B3654F158365C" modified="2014-02-19" version="1">MEITEVETFVVDADWRNWFFVQVKTDEGITGVGEALSGEGLTAALEATAESHKHYLIGEDPLNRKQINRRLTRYPFAWRGGKLINAVASAFDIALWDIAGKYYDEPVWKLLGGKVHDEIPVYANGWHIGERTPENYAHHAKKAVNEQEYPALKCDPFAHYEYSLTNDQIDEVAELLEAVRDAVGWDVGIALDCHGRFSRRGAIEVANALEEYDIMFLEEPVELEDREVMADVTDKVNMPVATGERIYNNATMEDLIRKQACDIIQPDLTNYGSLAELQHAAEMAKSRYMTFAPHNPNAGVSTAAGLHLCAGIENLEVLEHMSRDVPWGDEIVKHDFEVEDGTIEVPDKPGLGVEFDADAAREHPGEPKDSHSLFDAEGALKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF8</accession>
    <name>V6DTF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="6255" checksum="5ACF269A2FC180ED" modified="2014-02-19" version="1">MVQLRQIVYTPSRTVWAYLRYISRSGDETETEERLCFYERPFLVLRLLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTF9</accession>
    <name>V6DTF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="5130" checksum="13CCFE9DA3A98A39" modified="2014-02-19" version="1">MLNQQRNDFTNQEGNNDGLDNHPETSFKTVIHTWHIVRTILMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG0</accession>
    <name>V6DTG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_04889</name>
        <name evidence="3" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043816">
        <property type="entry name" value="DUF5798"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19111">
        <property type="entry name" value="DUF5798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7407" checksum="9B252F0A8DDCA5D8" modified="2014-02-19" version="1">MIDTSERVKTLENEMAEQRAVLDAVAEEVGVDLERVSTEAHIADAEESATDDGDADDTDDAERGNDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG1</accession>
    <name>V6DTG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5762" checksum="52C86E198F5F1348" modified="2014-02-19" version="1">MQQSIEPPILYGQIQERQEGEPLRTLLPRKQSASETESSSLTNSNLITTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG3</accession>
    <name>V6DTG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_10712</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="7"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="256" mass="27290" checksum="360C7C2FFCB79D1F" modified="2014-02-19" version="1">MPNSKASVICVAMQKGGVGKSTTAINLAGALAVTGSDVLFVDLDPQGNASETLGFREEYMSESQGIYDALVGSSDGDPDINNLVQEHDEMDVIPAHRQMVMARQDITDPTNLRAWIQSQGGNWDHVVIDTPPSLGPVTDSAVLAGDELVPVAQARSSSKRSITLLLDQLDELEDHFGGVPEVSAVVCNAIRPDSESKEMVSWLDDLGVPVVGIRTRVALQRAESAGVSTFVHSETSGMESEYRRLAEAVIGGCRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG4</accession>
    <name>V6DTG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C449_12168</name>
        <name evidence="1" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95569at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="18701" checksum="95F27D53481ED8D0" modified="2014-02-19" version="1">MTLSINPKDRMGVYKSLDQVPDNLRLKNYNSRYSGRESWEEFLDYYMNRRSSSESKRRRSERAWESWCDFTADNNPVLATPAAVERWTESLIDEYQTSYALKGYWAIIERFYTWMMMHVDYPHTYQPFWMAATEYEATKKIWDLKLSRVRGGKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG5</accession>
    <name>V6DTG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
            <ecNumber evidence="5">3.6.3.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_01111</name>
        <name evidence="5" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.20" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="263" mass="28884" checksum="AD64F3E40CF54E2B" modified="2014-02-19" version="1">MTVRENIEYPLKVRGIPPEERDERVAQVAELLHIEDQMGSDPGEISGGQRQRTSLARAIVREPSVFLLDEPLSNLDAKLRLEMRSELKRIQNELGITTVYVTHNQEEAMSMGDKIVVLNDGTIRQVAEPEELYQRPRTTWVAKFIGSPPMNLFEGESRDGTVHLAEGNTLPTPAESSSSTVSVGVRPEDIDVSTDPPDTDWTLPGTVKTVEPLGEYVLVNVEVGGSVVNVKVPHTDATAGDAVHLTFDPADAYLYDENGELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG6</accession>
    <name>V6DTG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4911" checksum="C7AFBA6E9D14F01A" modified="2014-02-19" version="1">MRTHYEVLTLLQFSDCSYPHNSVVRSKVAVTALICTGNSRVISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN0</accession>
    <name>V6DWN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na+/Ca+ antiporter, CaCA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_05848</name>
        <name evidence="7" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077329.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45269at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="10"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="176"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="316" mass="31947" checksum="2B9C8C6DF220AA55" modified="2014-02-19" version="1">MLPGSPLVELLLIAGGVALLYVGAELLVSGASDFALAVGLKASTVGVTVVAFATTAPELFVSLLGAVTVSTDIGLGAIVGSNIANIGLVLGVSALIRPLDVSDTVFRRHVPFMVVAALLLVGLGWDGRIGLVDGVVLLAALVAFTAAVLRNVQQNQSAISEAERDEMPDAKARDVAAVVGGIVALVLGSRWLINGGESLLSAAGFSDIFIGLTVLALGTSLPELAASVVAAVRGEAEFSVGNVVGSNIYNVLAVIGIVAVVTPIGVSPAVRGFEFPALLAFTAVAVGMMAYGERITRVDGAVLVVGYGSFVYLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN1</accession>
    <name>V6DWN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AsnC family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_05908</name>
        <name evidence="5" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077320.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97695at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15335" checksum="F688D64447224AE6" modified="2014-02-19" version="1">MSTVSTEERILSVLEEDAQASCGEIAERADVSKPTVRKYIDRLEDRGVIVGYSAEVDPKKLSSQSIAMVGMDVDSGQYVGATRELKSLDEVQALYTSSGDHMLMAEVRAGDGDELGDVISEKLLGVEGVTAAHPSFLQERLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN2</accession>
    <name>V6DWN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5660" checksum="B9A6223E7563F8D4" modified="2014-02-19" version="1">MTGTVKAAAFWAAIAIPATYPVLLHSGLDGGTGQLFVALLFANALALALGHDHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWN9</accession>
    <name>V6DWN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative selenoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C470_11147</name>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078132.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116512at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8698" checksum="8BB02F98F2991EB1" modified="2014-02-19" version="1">MTRVEIEYCVPCGMLNRAQDVSEAILKQFGESIDEVALVTGDAGVFVVRAADEVVFDKEEDEYDVDAIVRAVKPYVGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX00</accession>
    <name>V6DX00_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps14P</name>
        <name evidence="3" type="synonym">rps14</name>
        <name evidence="5" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds 16S rRNA, required for the assembly of 30S particles.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004597423.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38951334"/>
    <dbReference type="GeneID" id="55595005"/>
    <dbReference type="GeneID" id="65214309"/>
    <dbReference type="OrthoDB" id="122051at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_A">
        <property type="entry name" value="Ribosomal_S14_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="40S_S29/30S_S14z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023676">
        <property type="entry name" value="Ribosomal_S14_type-Z_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="PTHR12010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6656" checksum="6F9C36B312284E76" modified="2014-02-19" version="1">MSEANNDTGEHAAKRTDSRHTCRRCDREQGLVGKYDINLCRQCFREVARDMGFEKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX01</accession>
    <name>V6DX01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_12771</name>
        <name evidence="1" type="ORF">BN903_122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5837" checksum="40BD93772FB3BEE3" modified="2014-02-19" version="1">MDAVSRNERYHLVCRECPLERLFDTAVDADAIRRDHVDETGHRVAVDRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX02</accession>
    <name>V6DX02_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoU</name>
        <name evidence="3" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077811.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76473at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="119"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="224" mass="25197" checksum="147D7DE93B4BB12D" modified="2014-02-19" version="1">MPREEYQTKLEGLRDDVLYMSEVVAERLRMGLDALERQDGELGEEVITGDAEINELYLELEGQCTDLIALQQPVAGDLRFIAASFKIITDLERIADLATNLGEYAKRADREVFPDVDVQRIGDDTLEMLEQAMAAYAESDPELCHAVAEADDEVDAACEAASELVVRDLIERDELREEADVEGTMRNVSRLLLTIRDLERVGDHAVNIAARSLYMIENDDELLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX03</accession>
    <name>V6DX03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_09973</name>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="117" mass="13571" checksum="3E0DFE17D4AD6988" modified="2014-02-19" version="1">MGRRGVHTGMKSARAAAATVDRCLTDSERRLDAESLAVYERLWHRDVAPRMKARLMLTRLLYLAPNERYDRFMRDLRRTDENTLEKANQGDKAAMAELLHLSDLPLLTKFARERLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX04</accession>
    <name>V6DX04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_10628</name>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078265.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31160at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="491" mass="54103" checksum="C8283CBA2804E04C" modified="2014-02-19" version="1">MDWSETVSRSRRAATRRAFRRRVEEQARSLRATLKTGEFKGGFRLGLELEGYAVDGDGRLAAAPEAAVSSVCEPELGRHNAEINTPVTGFDAAGVVRQADELTERITAVREAFAARDRRFVTDGIWVIGSSEGAVAYLSATETKCGTEVPANLSPEARYYALDADITADGPVELDLPGCRRAFQSILVESLAASIQVHLQPPTSEYARYFNAALRTVGPVVALAANAPFLPPELYTDADAETVMTAGVELRIPVFESMNVRSPGKVRFPRDIESPTDAVDRIVDDRLCAPHLREWLADAPRGGFEADHWEFLHKQGTCWRWVRPVFGPEGPRIEYRPLAAQPTAADVVGLQLLVAGLIHGAVTTDHPLIGLPWRAARESLYAASRDGFEADLAWVTRDGERTDDPAAVYPDLFALARVGLRDRGLAAARIDSLLDPIERRWTTRTTPATWKRDRVRARLDSGDDLATAVTGMQREYIRRAETGEPFADWIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX05</accession>
    <name>V6DX05_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps17p</name>
        <name evidence="2" type="synonym">rps17</name>
        <name evidence="4" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078231.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108145at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_A">
        <property type="entry name" value="Ribosomal_S17_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_S17_arc-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019978">
        <property type="entry name" value="Ribosomal_S17_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="12826" checksum="4BC38F017EC6370D" modified="2014-02-19" version="1">MAIGIDVPTPPEPDNPEDYDYEKCPFYGQLSVRGQTREGTVVSTDMAKTVIVEREYDVFVPKYDRYMKRRSRIPAHVPGVLDSLEVGDEVTIAETRPLSKTKSHVVVEILSGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX06</accession>
    <name>V6DX06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
            <ecNumber evidence="3">6.2.1.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_12751</name>
        <name evidence="3" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.26" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008756">
        <property type="term" value="F:o-succinylbenzoate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="337" mass="37538" checksum="5869D8B5F8299726" modified="2014-02-19" version="1">MHKPLLTTDFLDRARRHYADEEAVLAVDGTRYTYAELGERADRFSAALQERGIEKGDRVAVLDPNTHYHLEAAYGAMQVGAVHTPLNYRLTPDDFSYMLSDAGVDAIYADAEYAANVEAIRDEVPTETFLTNDADAVEGDWESFDAALDDADPDAYQRPEMDEDEVITINYTSGTTGDPKGVCRTHRAETLHAYLISIHQEITDDDVYLWTLPMFHVNGWGHIYAVTGMGARHVCTRGVDVAETFDRIRTEDVSYFCAAPTVLNMLGDHHAEHGGATTGDADVRVATAGXXXXXXXARARGRSRRASRPPRRRRPRRRRSSRPSRCARGRVPSRSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX07</accession>
    <name>V6DX07_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_02859</name>
        <name evidence="6" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="27"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="409"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="483" mass="51973" checksum="AAB88F7B814867F9" modified="2014-02-19" version="1">MRLSDRARTLPESGIRKFFELAEARDDVISLGVGEPDFSAPWTARTAAIDSLERGKTSYTANRGMAALRERIADHHGRYDQSYDPGEEILVTTGASEAVDLAFRALVDPGDTVAVHEPTYISYGPGIELAGGEQLTVPTRAEDDFALTRSALEAAGAAEADLLVLCYPNNPTGATMTDEQLAEVAAFCRDNDLRVVADEIYAALTYGGDHASIATQPGMRERTVVVNGFSKAYAMTGLRLGYALGPAEAIDAMNRIHQYTMLSAPTTPQYAAIEALDRCDDEVAEMVDEYDRRRRLVVSRFNEMGLDTFEPGGAFYAFPDCGGDDEAFAEELLEAQGVAVVPGSVFGEGRIGPPPRVVRDLDARAEGGDRPHRGVRRGAGLTAPECRRSGETARAPAITGDFGNESLSDARAPVTSWRANRASRSSTSTTKTSSASWSPRSCATRATVSASARRTRPRAVPGGWRTERSTAYSVIITCRGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX08</accession>
    <name>V6DX08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-I</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_02616</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077433.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54766at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="25960" checksum="41B39559A6C1A0D7" modified="2014-02-19" version="1">MTRLRFALLNAAHDGANTRRNFRREIDADLVEFDATAGDLPDHTEFDGVVVTGSRSSVYWDEAWIPPLVDYVAEAADAGCPVLGVCYGHQVLAEALGGRVAGMDGFEIGYNEIRRTRDDPLFEGFDDSFTAFTTHGDAVVELPPSATLLAENEHGVHAFRDGHCWGVQFHPEYDVETAREVTDGKRDQIGDARVDAVLDSITPAAYDAACEAKALFENFTAYAERLASDETEPAAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DX09</accession>
    <name>V6DX09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6034" checksum="27C36588139EF80F" modified="2014-02-19" version="1">MLREKAGLRGYSDRDELLPGSTRVVGKRTGRDSRERSERESGRGTTERSAPAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK7</accession>
    <name>V6DXK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4508" checksum="5CF23487D7D8FC06" modified="2014-02-19" version="1">MSLGRDVNHPARGDARLVSELCLHRRSVARDESPIRRHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK8</accession>
    <name>V6DXK8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">V-type ATP synthase beta chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">V-ATPase subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpA</name>
        <name evidence="7" type="synonym">atpB</name>
        <name evidence="10" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077992.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8899at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="PTHR43389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="9">
        <location>
            <begin position="7"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="8">
        <location>
            <begin position="129"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="474" mass="52732" checksum="E4A525ABD0B3CE8A" modified="2014-02-19" version="1">MKEYQTITEISGPLVYAEVDEAIGYDEIVEIETAQGETLRGQVLESSEDVVAIQVFEGTSGIDRDASVRFLGETMKMPVTEDLLGRVLDGSGRPIDDGPEIVPEERQDIVGAAINPYSREYPEEFIETGVSAIDGMNTLVRGQKLPIFSSSGQPHSELAMQIARQASVPEEEEGDDDEDGSEFAVIFGAMGITQEEANEFMQDFERTGALERSVVFMNLADDPAVERTVTPRMVLTTAEYLAFEKDYHVLVILTDMTNYCEALREIGAAREEVPGRRGYPGYMYTDLAQLYERAGRIKGRDGSVTQIPILTMPGDDDTHPIPDLTGYITEGQIYVDPDLNSQGLQPPINVLPSLSRLMDDGIGEGLTRKDHADVKDQMFAAYAEGEDLRDLVNIVGREALSELDNKYLDFADAFESEFIDQGFETTRDIDETLSIGWDLLSMLPKDALNRIDEEFIEEYYREDDAEREAVEAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK9</accession>
    <name>V6DXK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="9824" checksum="FF6538CD783CC0BD" modified="2014-02-19" version="1">MRRVLFGATRSCSCAAAHVEPRARPPSRTPEIPRSRTERQCHSSWPRSRRCSSTSRGATTPSSRTATGTACSAGGSNSRIRPPARVRRSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL0</accession>
    <name>V6DXL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5031" checksum="26ED2378BA141B5F" modified="2014-02-19" version="1">MLIPNTSLKTYLNGTTSHMRLSSAQEDTSPFSTLGVSTEVVGTTERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL1</accession>
    <name>V6DXL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="12365" checksum="18314CE72879233F" modified="2014-02-19" version="1">MSDGSNVPAACATASAAVGRSSVASSSVEFVDGPDWSVAGSVSVASRVLGPPGPAVVPAVERASVVYYGRHVSLHGRILHNCLCWCEDRRGEGSHGGPARHRQSVRSPEGGFGPTRPTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL2</accession>
    <name>V6DXL2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">V-type ATP synthase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">V-ATPase subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">atpD</name>
        <name evidence="9" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078000.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93236at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00271">
        <property type="entry name" value="ATP_synth_D_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="PTHR11671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="233" mass="26249" checksum="C99E50EF7EE91A10" modified="2014-02-19" version="1">MAKDVKPTRKNLMAIEDRIELSERGHDTLEQKRDGLIMEFMDILDQAQDVRSEVSENYETAQRKIDMARAMEGDVAVRGAAAALKEHPEITTQSKNIMGVVVPQIESSKVQKSLDERGYGLLGSSARIDEAADAYEQLLESIILAAEVETAMKKMLTEIETTKRRVNALEFTLLPTLYENQEYIEQKLEEQEREEIFRMKKIKDKKEEEEAAEAAEAAAEAAAAETEDPEPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL3</accession>
    <name>V6DXL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6523" checksum="A1D3E3D026FA8CFD" modified="2014-02-19" version="1">MKRATRCVVRESEALSSSRKALRAFRTTASVCPPRDWGFGGVRVDQPFISRNTVVQPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL4</accession>
    <name>V6DXL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7449" checksum="0A1EC48DDF86A53C" modified="2014-02-19" version="1">MVGDSEGFHSMEKNVRGHKLTYRPYSRGLAARSVEKSRVCRVTQREVLTPSRVNRRGHVTVKSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL5</accession>
    <name>V6DXL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_14112</name>
        <name evidence="7" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077602.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49280at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="441" mass="45533" checksum="6CC5FA674BFECF61" modified="2014-02-19" version="1">MSDANTPNTAPDAPESATAAVIEAAKESDLGLVVGTLLVIYAAAALLSFTDGLNSVVGLMETLTFLGLVYALTALALNLQWGYTGLFNIGVAGFMAVGVYTMGMVVRSPDPAFGPPGLGLPLPVGILAGMGMAALLGALAALPALRLKADYLAIVTLGLSEIIRLSLQSSAFDTLLRDTIGAGTGGGRGMGMPDNPVRDLFLVDGQAGTPTAFGDLVFGVFGADGLGISQPILIGWGYIAVLAVFLGGFYLLLERLGRSPFGRTMKAIREDELVANSLGKDVNLVKIKVFVIGCALMGLAGILWFGSQGNVSPTPQFRPLLTFYVFIAVIIGGSGSNTGSVLGGIVFAAVLFEGPRRVGGAIRGLIDAETPGSFADALVTLDPVTLLAYATENVAPLQFVFLGLVLVFIIHRRPEGILGDRIETAAAVDLSERPTGGESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL6</accession>
    <name>V6DXL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="436" mass="46743" checksum="0DC8423D1DEA4B43" modified="2014-02-19" version="1">MELEVGAGFVLARANEPAGLADVGGELPALEHEPVEDVPQPASVVERAHVVGRLVDGEGEQVVLKVPTDARRLDRHVDVMVREVVRVSDAREHEQLRGVDRAGAEDHLLARAGAAGPAVLSVVDAGRMAVLDGHRRHLRAGLGGEVRAVEGGLQVRVGRAVAFSVLLRDVVQADALLCRPVEVVVPVVARRGGGADERLGGGPRRGLFGDAERSVRSVVRRSSRAEALRPLEVLQHRVVLPPVVAQFGPVVVVGRVAADVDHRVVRRAAAEGLAARPVQLPAAAVLLRLGVVLPVRRGLEQLRERRRNPDVPLVVRLARFEQQHGRLRVLCEPVREDAARGPGTDDDVVVLAFHHGRSCAGRPIKCTRVTHRPSARAPVPSRSRRFDGADRDPPPSLVHLYTSRRVVRACPASPSASTRTSTPRAATTGTSRSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL7</accession>
    <name>V6DXL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphate/phosphonate ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_05092</name>
        <name evidence="1" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078004.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45846at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="335" mass="35866" checksum="6D3FBC791CC4C11B" modified="2014-02-19" version="1">MSDNRWAADRRTFVKTAGAAGAIGLAGCSGNGGTSGETDDVPTARFVLNPAESDVAIEEQYQPMFEYLESEVEVTIEPSRAESYTATLQAIRNDQGEIADISPSAVIAGEDILDIVGVRIAYGAAQYFSTVTTTPDSGIESLSDIEGELIYMGDILSVSGTLVPLTLLQNAGLDVGDAPNGDPGNFEAEFSDHTTAREQMVQRDDVMAATTGAFSSAPYVPQAQFEEMSQDFVDISAEYEGAGDEIESSGTELQLLAVSDPIPRAPLVTRSNWDNSVKGDLEEAMLNVTEEDLSHGDDYDGEPLWFTGVQEGSIDDYQPIRDVLDQLGLSFEDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM0</accession>
    <name>V6DXM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5499" checksum="90F90E9E94AA20DE" modified="2014-02-19" version="1">MPQLVSGSALAILGHFPKWFDRRHEAALGGIVQPVSVYRFSRNHASHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM1</accession>
    <name>V6DXM1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C440_12224</name>
        <name evidence="3" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077613.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107094at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="57"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="19616" checksum="7F696BA3B828E48E" modified="2014-02-19" version="1">MEDTPTTADKRVVEGLNFGSKTAKRVGWEQFEFAVESPYLVRVTNASYGFEKSDHSYLVGVEERDGLLVPAECECPADKYNDEYDCKHKVGLATIAGPVVLQAAVECPTPTHDTEGTDSTTLAERLRADGGAITEARRDEGRAGVIEAERGKECPNGEEWCEPDGDSLPCFACFNSTESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM3</accession>
    <name>V6DXM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000032">
        <property type="protein sequence ID" value="CDK41092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="15859" checksum="D2BA37B73B8DD3C1" modified="2014-02-19" version="1">MFVRVHRPGVDVEVGVHLDGGDVEARVGEKTPGAGGGDALAQPGHHTARDEHELPTHRGVVPRVGICWHIDRPSGRVKTVSDPTFRVDVRVNSGRVGLSWRGMCHRRGDDSGSIGHRFISRGARIRRKRRQNSGRLIIRRGSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM4</accession>
    <name>V6DXM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C485_15696</name>
        <name evidence="5" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077616.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20145at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="203"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="397" mass="45961" checksum="13D0CAE9CDF2CD2D" modified="2014-02-19" version="1">MNPSDPLDNLGGGNAMSGGVPPAPEDYEFTYPLVSGRSEEDLEGFGMNMVDDYRDFKHELLSWLAHYGKHPEKREGLADTTLESTHYKLETAFRWLWRHEDQYTTKFTPEHADKFIRVLNQSKGMIDSTVLHHAKDIKRLFKFYNHSRGKDYEWDVEIELSQSNGGDERDYLRRSAFDPLYQAALEYSSVKSYHSVTPEERDRLKIFVSQRLGIPKEKVGPEEFKEANSWKYPSIISTALDTGLRPIEVGRAKVSWVNLEDEELNIPKDESTKNEAIWNCSLKGRTAKALKRWLDERASLPKYDDRDELWLTQTATQYGSKSCNALLRRLIENGDVPIPEHKDVTWYSIRHGVATYWANHVGPHHAREQLRHSSLNTTMKYLHSDAETRNSAVEQIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM5</accession>
    <name>V6DXM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_16277</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="228" mass="25886" checksum="895FBC1E7547F095" modified="2014-02-19" version="1">MADYQHELETLREIDSNFHRLFEAVNDTDDVVSMPGGDPLATLRRARAQIDAALFASRRRRDDATLANNGACLLQWNPPSAPPRRLRFEPNTTGESWTRRELEWTGAEWRSCGSDPVEDVAIRAPAVARYPVPVDPTPIETMLEWIRDSWRRPDPPALVFAATATTEQGVAVSVNGELRYRERDSPQWYPATTDEFYHHLRTHGQPTLQPLSETGLTRHEFTPSPLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM6</accession>
    <name>V6DXM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5424" checksum="2804180D5727215F" modified="2014-02-19" version="1">MNHQPDLRDAHRVSPCGRGYDERGYSEELPDTLVSYIFYTNPIPILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM7</accession>
    <name>V6DXM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH-type endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_00847</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078023.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117895at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="170" mass="18692" checksum="4C38616339319321" modified="2014-02-19" version="1">MSDDNDDASEELGKTGEKMGGIADRFGATTEATDTTDTTETDETTDTTETAETTETIDTTEETSTPSSEMTETTEATTTTETSETIETPETTDTLGPGDEGFVLREDWNGRTIYLPDDVVDDLDIRYSEVNVEWQREHGEQLPKNERFYPALVRAAINETTIEAELGLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM8</accession>
    <name>V6DXM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-export membrane protein SecF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">secF</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14363" checksum="1B229FD50015BBCC" modified="2014-02-19" version="1">MMAVVASVFGIGLLRDIGIILSVGLCADLMNTYLMNVSLLRWHKFEGVETLMLEPIEGELADPVARRRRDRCHGGAVRARIRAGAGPRRRRERGPRGDHEPPVRAGPRGRDADPRAAVGIHRDRRRVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXM9</accession>
    <name>V6DXM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11621" checksum="C31371C44833D8A5" modified="2014-02-19" version="1">MYPLKNTDILLVNTIQKVVFNLSETRQESFLPFFYRLPPHRGADAVDSLRSGAYNRPRPRPRRWTRVAGHELPVGTPHPYIAGVNLRPHRSYSLITAVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN0</accession>
    <name>V6DXN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5045" checksum="EC2C1C335E4A4256" modified="2014-02-19" version="1">MTLLVRRSAKGGVSRTDRRRFCDSGESVIQSAVVGHAIKNQPSPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN1</accession>
    <name>V6DXN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_08725</name>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="12632" checksum="3C6E0ED5310644D5" modified="2014-02-19" version="1">MVVALLFRTNNFQLFAAFIPLIGFWYLDAYYLRQERKFRKLFDWVRLNRDDTDDYLFDMDPSRFEDDVDGTVQLMATKSMLTFYGTIGGLLIVYTVILICINGGTIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN2</accession>
    <name>V6DXN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TrkA-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_08615</name>
        <name evidence="7" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of a potassium transport system.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="136"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="221" mass="23491" checksum="AF1B8D38AD7F07B2" modified="2014-02-19" version="1">MERLVDLTNSAARRFGAGETVVVGYGQVGKTVADALRTPTSRHVVDREAGEAVDVVGDATDPEMLRAAGVADARTVVLALPDDTTAQFATLVVRDLAPNVELLARVADPESVPKMHRAGADYVLSLSLVTGRMSASAVLTDRDVLSLDTHVEVVRSETPTLVGRTVGEAAVRERTGCTVIAIERGDELVTDVGPETRIERGDELVVVGTDEEVRAFERAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN3</accession>
    <name>V6DXN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Di-trans-poly-cis-decaprenylcistransferase</fullName>
            <ecNumber evidence="2">2.5.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08570</name>
        <name evidence="2" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.31" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008834">
        <property type="term" value="F:di-trans,poly-cis-decaprenylcistransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9734" checksum="809729951197DF82" modified="2014-02-19" version="1">MADGEITPETIDESDVADRLLFPEEPDLVIKTGAERLSDFAIWQSVYAELYFTDVNWRDFRRREYLRAVLDYQDRQRRFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN4</accession>
    <name>V6DXN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7058" checksum="0E4BEE94970FD251" modified="2014-02-19" version="1">MVKEVVAAGASEAVIEQTSKEAATRGLAEGSQGTDRAFSGSAERAMESAMGDIMTEGADALERHRDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN5</accession>
    <name>V6DXN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000032">
        <property type="protein sequence ID" value="CDK41094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6948" checksum="9BAA2355E1FBA06B" modified="2014-02-19" version="1">MMRKGALGAFFPRKTSLERDQRRLFIIRSAVARASERPFKGARSAARGSQRRPTGAADEAGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN6</accession>
    <name>V6DXN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA topoisomerase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06590</name>
        <name evidence="1" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000032">
        <property type="protein sequence ID" value="CDK41097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="15344" checksum="72139C5C548ED19A" modified="2014-02-19" version="1">MRSRGDVVCLDCETRWGLPAGASVTDATCDDCGLPKVRVERGEPFHLCLDPACDPLEEAVGDRFDRAWPCPDCDGDLAVRYAPGRVYLACERDDCETTLSFPAGVVVDECDCGLPVFETAAGRSCLDGSCELAGHAAVKSPDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN7</accession>
    <name>V6DXN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C464_05890</name>
        <name evidence="7" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077625.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80417at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="233" mass="24382" checksum="FF82E78CEF437789" modified="2014-02-19" version="1">MTGYVEIVAIAFATQLAVLPGEKVQLMIAGLSTKYDPKIVVAAAGSAFAGWTAVEIAFGQAIQSALPPIALDVVTAVLFFVFAILLYRSAPSPKTSAEAERTDGGLAAFDDLSLPGRLDRYSGSLGGFLPIFVLTATGEFGDKTQLVTIGLAVQYGATSAIWFGEMLAIIPVSLANAYFFHRFAGSVDMRLAHFASALLFAFFGADTVLAIATGFSVWETFVGAFGGLIGGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN8</accession>
    <name>V6DXN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15192</name>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078032.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="85128at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="20103" checksum="7953398D6B5BB87C" modified="2014-02-19" version="1">MVLTSAKDQLDEDEISLADNEEIIHALSELTPVYENDRSYFVLGNYDREPIRRLNLVVDRLSRRQDAYAFRMVDIRGEWDNSIQKFCLIGDIVTYLVGVAEKEPSDFLVEQGLLVGTTEFFAKSHVLKQEYDDEEHPFGWMQDGVFDLFEQEGRLYRWQTEKDLVDVTDDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXN9</accession>
    <name>V6DXN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14231</name>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077631.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90597at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41913">
        <property type="entry name" value="PTHR41913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="181" mass="20784" checksum="8B9237B1F9FDF626" modified="2014-02-19" version="1">MSDDYAERLRANRREKDEFFAEHQQSPIPPEQRDEFDGLDYFEPDPAYRVEATVTVHDEPEPVEMETTASNPVRYLRVVTFAFEVDGEERTLAGYRQEGDDGAIFVPFRDKTTGQQTYHQGRYMELAPERDLADGDAVTVDFNLAYSPFCAYSETFSCPLPPEENWLEIVIPAGERTPDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY00</accession>
    <name>V6DY00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5298" checksum="57BADB069AB29826" modified="2014-02-19" version="1">MGRSAAIRRPNAARDRPWRVLPHWSSPTAGVTRCTDRYRTFQGVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY01</accession>
    <name>V6DY01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amino acid-binding ACT domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11360</name>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008585285.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71317at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014424">
        <property type="entry name" value="UCP004897_ACT"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004897">
        <property type="entry name" value="UCP004897_ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="97"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18267" checksum="565637B36A7D5EDD" modified="2014-02-19" version="1">MFDEILEKFEGSPSQQAVIRLFLERGFSVNEEGRVVSGGIEIPYTGIARELDVDRRVVDSTTDAILADPELKRIFTNISSIPSLMDLAPVLDLTVLTIEVAAADEAGIVAEVTSILGDRGVSIRQVLSEDPEFTDDPKLYVITDAELPGDLLVEIRDLDYVRRVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY04</accession>
    <name>V6DY04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13382</name>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078142.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116102at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14242" checksum="110503DD48B070FD" modified="2014-02-19" version="1">MYDRTFGTGWDDLSREEAIERAFALGVAAGVDSPRPDELDRVLEAFPGSYDRSIVELAYDEGRTKALEAKAERDDPDDEAVWDSLVDGLGAPRESPVPAALPGAIRELTLTERPREGPPSSLDLPSMLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY05</accession>
    <name>V6DY05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_2633</name>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004047560.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7400838"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015207">
        <property type="entry name" value="DUF1931"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09123">
        <property type="entry name" value="DUF1931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6149" checksum="793BDE983B862D5D" modified="2014-02-19" version="1">MADLIVKAAVKEALDDKNVASDFYDALDDEVDELLEDAARRAEANDRKTVQPRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY06</accession>
    <name>V6DY06_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHOCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_06834</name>
        <name evidence="4" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077719.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112379at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="3">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="13062" checksum="A4C40FF1740D27CA" modified="2014-02-19" version="1">MDDGTGAALLSLAIAVPIVGALLMSGTVFGAVLTGLIVGTIAVSFVLADRIDDEKDETVTDDEPGPLESLRDRYARGELTEDEFERRVERLLETEDRSTARDLLLDERDGAAETEPVRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY09</accession>
    <name>V6DY09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5354" checksum="BEDAAF5B0E2FC612" modified="2014-02-19" version="1">MPVISPASRSPEAICVGAGVDMDTSPYDGGPHIARRGFGKFHHVSRPSGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP50</accession>
    <name>V6DP50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_08570</name>
        <name evidence="2" type="ORF">BN903_207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="267" mass="29803" checksum="7274E0AB15F3E6D3" modified="2014-02-19" version="1">MADYFCGRGGVGNALDKWLPRHMYFGVDIEPYGDDYPGQFLQADLISPFTSQHRDSSETNLPFSGTIADVAWVSWPCTAYSSLSATHYGSKEAALEENPRIPDAFREWLLDHHAHYVIENVEGASRVGDLDANCRVNGLAFGEPYSMTRHFETTFDVPDAYIQGNPDLAIDTRGDQSVKELAEAKGVPDSWSGRKQDVRSAIPWQYVWWILGHCPAIEIPIPKTKNRSVAEWGDGVGHYLRYPTDRLGGTDHTPEDELSSGPRGEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP52</accession>
    <name>V6DP52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Terminal quinol oxidase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_01864</name>
        <name evidence="1" type="ORF">BN903_141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4467" checksum="DB447E4C3279A73D" modified="2014-02-19" version="1">MHNFWAVDEEERDGELTSFLQNLTLLGAALAFLSRARED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP53</accession>
    <name>V6DP53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV leader peptidase family protein</fullName>
            <ecNumber evidence="3">3.4.23.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C442_01937</name>
        <name evidence="3" type="ORF">BN903_219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.52" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075901.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87374at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="2">
        <location>
            <begin position="14"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="335" mass="37132" checksum="A1E53D1E53DAF9CE" modified="2014-02-19" version="1">MIDADPDLLRLLAIAPLAWAAWSDHHTRRVDRRVWAVLIFIGAIAAVWQVDQIAPIHTVDEYRILTQLIIVPPATGFFALALSRTGAFGGADVKALFALGLVFPTPIEYALPALSILLPAHRGQIAVITIGFNAMLFGAILYLPKMWIQNYRRGERTLNLLITKKIPVHKIPETAGQMRWTDETGEPYTLDLDALRMYLRWKNVTVEDILQHSDDHRTATEIEAVYEIDEGVVYSKIPSSHPLASEDFDSHENPVIADTNVPIEKDDMWGAETFLDSITHTAYGTSPDNLRGSLEHILTAQSVRIQPVVPLVVPLFLGVVAAVTIGNTVTLLTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP58</accession>
    <name>V6DP58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TATA-box-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tbp</name>
        <name evidence="4" type="ORF">BN903_224</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11271" checksum="DED3ED6C248E3A4E" modified="2014-02-19" version="1">MDTQLMETISTENVVASTTVGQELDLNAVSQDLLGVEYDTSEFPGVVYRTQHRRRHLLSSARGRSSVLGQRTSTLLRNRSRVCSMSFATSESMLTTLTWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP71</accession>
    <name>V6DP71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C443_03309</name>
        <name evidence="2" type="ORF">BN903_227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075907.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42416at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="284" mass="32001" checksum="FB23E4633E75BF19" modified="2014-02-19" version="1">MDPNNDSANCEAQFLEESILEAGFGSYIQSEYELPYFVDVDYPESAPDTPREYLIGLAKRVLNAGGNRTGFTHHTEIRRSLHGWAPEYNEDVDDDPGYWGECAFGLSSHEINFGRLEGDGETKEQKARTVLARARDNIDAEVLVEIEENYVSDTRSMWDEAAALADGELQIRKFQNSPPDNVGGWHRFDTSDERVKLAYRANNHDVPVVIGVYEDGEDLDVHEWTIENWEANNGDPLETPKNRFPASTRTNDGPYARLRNHLQTYDADPLPVDTETDTNSSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP73</accession>
    <name>V6DP73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease self-immunity family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ZOD2009_02650</name>
        <name evidence="2" type="ORF">BN903_239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334869.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95484at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="257" mass="27750" checksum="346C5300B99BD4B6" modified="2014-02-19" version="1">MDHPDGSDLLTDLKDKLRTLGIASVLGFGGYGLSIFWYTPFRLASDLPSFTPGYGEAMVMNDIALGLAAVTIGILYLKYSGKGREYIDLEIPTKRRTIFVIGGTLSLLTALYAINSLKSHLNVDASQHTASQAVAAGSVDPQYVLLMIPLSFLLIGPAEEFIFRNLVQKRLYESFTKASSVIIASIIFSAIHIPAYATGTTAGLLTSLATVFTLSLFLGGFYAMTEDLIVVAMMHGAYNAVIFGRWYLAIAGSPLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP76</accession>
    <name>V6DP76_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like_fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C461_04527</name>
        <name evidence="4" type="ORF">BN903_232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="167" mass="18223" checksum="8BF25225CFC73A93" modified="2014-02-19" version="1">MFHDLSNRPTWAFTTHALSAILDDYVDTGTARIEFYDLPVPGDPDWAHQLASVARYIYAEAGQDGYRSYIETAAELFSSDQPTWQGVGDAASAAGVDPCTAIAHGSWKTYESDTEADRRYAHSLEIDAVPALLIDGQRLSDINPVNRSEGKISAAIEKALENSSGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP82</accession>
    <name>V6DP82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ZOD2009_14496</name>
        <name evidence="1" type="ORF">BN903_166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="10102" checksum="1E1FE2F9C9C7A750" modified="2014-02-19" version="1">MEGLLFLVLMWRNESSYSTFKRFLGVIGLLALLYPRTYVNYGAELAYVDGTNCKWKPWVYPGTRIVGLLYVSIALNELRQNRLSYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP84</accession>
    <name>V6DP84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075927.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117021at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="347" mass="37959" checksum="9B09BB1924A42C85" modified="2014-02-19" version="1">MTETQESLSAFSTPDTSSQSTPQKQDETCEQPEQSNAGKTTTPTPTTSPQSKTPLTDLYEDVEAHIEEAYPAFLRDQAIVTPPDPENQRYRTNGIPTAVDALPDTIGQWKLVTHDATHVSYLADGPAYDTEYGKGGSLVRFKLSLNDRGANRDDKYHLRTEKVVGYTNGEKIRSHTPDDESPMLGIRGHSVGDNPGDFSVLGGTKRKFGDPRDGIIDLIALLHHLPVPIRNYLPDTEDTPWEPVKHDLVSATWSTDAPDCVPKEDLILRLSTNQLRLTASDPSDSLPQKDTTTAPLVDPSFPDGLTGWLESKSAYTTVSSIRAVSAILTEDLTTVAEKSQLNTSESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP87</accession>
    <name>V6DP87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075920.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7521" checksum="4C636F076386F942" modified="2014-02-19" version="1">MPTLPLAFSTPLQVPLMLSLGIGPLQLMVLVLLLFSSTGLFIALSKQMSGGKALGSAAGLYVLMAGWTFLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP90</accession>
    <name>V6DP90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="161" mass="18349" checksum="389BFE75ABB16531" modified="2014-02-19" version="1">MTERLSEINFPLESCSCAHCGVSFPEASIPEMAKAIATHWNRQHRAVLAEVYTQFDAEAYHEEHIEGDLYGVFKETHYITAYDVIATTGVYPLSPEFTSDLKFRDVCVDCWEDVADIDKYTEVPDDAELAGKYLCIPCSEARQIERRQQNNQQLSRFSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP91</accession>
    <name>V6DP91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4582" checksum="B60239683F9B334A" modified="2014-02-19" version="1">MGLVEIDGMAADVSRRSVSRVALERVPPESRRDISQLRSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP92</accession>
    <name>V6DP92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075925.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="15444" checksum="934AA5A98613801D" modified="2014-02-19" version="1">MSSAHHPATSTETCIDYTETKHSVRLSHRDEPLEVTFDKAYEDAPTKFSVVAYEHQIADHLVKPFAETDFEIDTVHEDSAHFFLTTELHNVDSYEELVDVLSTVANYAWEYPGGCWLNVQTVESDHHSHVVATIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP95</accession>
    <name>V6DP95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Halar_0718</name>
        <name evidence="1" type="ORF">BN903_181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075874.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99832at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="7171" checksum="9BFB2637C14D3A8D" modified="2014-02-19" version="1">MNLSGGENVSESKYNQADPDIPCGLHFDVDHQQFRFWVDDYGVEIESQPTRSEIRSIAEDLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP96</accession>
    <name>V6DP96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075930.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="413" mass="45214" checksum="540130BDF6C11715" modified="2014-02-19" version="1">MSDSQPALSEFDGKTARTKPEPADTPPESISIPSHSQFESAGGEYPDSQIGALTDGSTISVSLCIPEGAVSVTFTHLAGSGGMGPTTEIDNRDEVAGLLDQLKGHPLLVTGGGMNTPMGCGFVLGRLTDTRAVDATVEVGYRELFRHAKRSRDTTETKRLGSYQVFVPETDHDSQRAAKALTHWEAGELEHLNPEKRAQEKAKEQHQEAFDSLSPGDKIETPEYATRLDIISEPYETHAVIPRGTLGEKTVPVTAVVVANPRGGYYQIGMNPNSDSRYRDGPTCYMSGSKKTPPTPNTAFTRDVRFGYSDIEITTIDHPPDPTVIEPDRTVLESPLPEPRLQTTLQSLDGIGEKTSRKIQRLADERVTADTLAWTLFGDGETHTGSQREIEKILKSLPKHEQIYDQLQKYTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP97</accession>
    <name>V6DP97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075935.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="208" mass="22817" checksum="091AFCA1AED6F8A5" modified="2014-02-19" version="1">MSDTTTVKQTEQPGPPPTHLPDPPKITGYQSSGGELGSPSTITLTVEFYTPGIAEPYETDVLFSITNGTAEFRRVEAQIGLSKSLIAVEAASKEVGKHPAVTAVEDVDALVESQRQWIGRCEQFKATGWVEMPEKPDSTIASCVEAYENKDGEQYIIWTTPEDNDNHPDILIEHHHGDDDETVDTTPCDTVDEAREKVTRETTGVTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA0</accession>
    <name>V6DTA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="12099" checksum="5B222A5235919B23" modified="2014-02-19" version="1">MTTEAASRWSPIPSRATDTVAYVCAPPRRDHATXXXXXXXRFPGDADRKRGRHDGQEGGDGQKHARHADRDEERDREQFASGRREEGRERESVQPVFGSRRHTLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA1</accession>
    <name>V6DTA1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Hlac_3380</name>
        <name evidence="4" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="17031" checksum="D870AE5C51227F82" modified="2014-02-19" version="1">MTIATGDSVTLEYTGQLDNDTVFDTSRESVAEETGLAEAQPDREYAPLTVEIGDEQVIEGMEEGLIGLEAGETETLTIPPEKAYGEPSDDQIQEFETEELTEMLGGQTPEEGTYLEAQNGSQGEVVHVDEEVVRVDFNPRLAGETLTFDVEIIDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA2</accession>
    <name>V6DTA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4353" checksum="6DAC85D9E323EE82" modified="2014-02-19" version="1">MGLTRSFATRQFVRRVSEAEIAQEISRCDRRARAVSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA3</accession>
    <name>V6DTA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C438_09826</name>
        <name evidence="2" type="ORF">BN903_175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="405" mass="41787" checksum="47FFBC3FF1560AC6" modified="2014-02-19" version="1">MLFIFLLLLGIVTTVGLVTAADSGYDIETESTIAVPEESETISQGGFSVTVESAKIAVIGPDEDLVVETTSPRENSYNVIFLNAQQDEIGNNDSVQGDAEVEFSAASEPPGSYAVIINDQSIVDAFLPVVIEAHQVDSFTLNGDPADGSDIAADEEVDVRVELTELSDTSISGVELVLWTDDSDEVHELERVDDHTYETSIDPPEEGEYRAHVRVRGEESAEGEKELIGLSENRDVTVSASDGGTGGTGNTGGSTGGEDGTDGGSAPDTGTDTTDSANGTDTTNGTDSANGTDTMNGTDSANGTDTMNGTDSANGTDTTNGTDTASGATDDSADDSSGDGTDSDGSTTDTSDSTDSTNDDDGPIEPNNETDSSDETADSTPLYAIQGVLLALIAGGTLRRLRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA4</accession>
    <name>V6DTA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Multicopper oxidase type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11901</name>
        <name evidence="1" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4266" checksum="E2502D3FCC26914D" modified="2014-02-19" version="1">MNHAMNGDTYPGGMIGGMVYDSVTDTEQFASMMDLAGYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA5</accession>
    <name>V6DTA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_03990</name>
        <name evidence="1" type="ORF">BN903_218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5286" checksum="14DA94C58DCBA41B" modified="2014-02-19" version="1">MRDTDQIPDEESPYECFECGNIILAEDNPGSCPDCGGEMRNRHTPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA6</accession>
    <name>V6DTA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077059.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9486" checksum="20BA10AC27578F73" modified="2014-02-19" version="1">MGDPSGGDPDVTTWPPNALYRPPIERIGAALWVLALVSVLVVGAFLDPAEIGFSWRTVILTGLRVFAGVFAFFAVFPVVRNVRFLPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA7</accession>
    <name>V6DTA7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">bPH_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_06759</name>
        <name evidence="3" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076264.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102203at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="69"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="176" mass="18831" checksum="B596190DCACCDC5B" modified="2014-02-19" version="1">MSDSWLFLRDGETVVWEGTPRLSAAVGGIAVGTVIVGLCLAAAATIDPRLAAASLVGIGVAAWQVLRIRRTRYVVTTRAVWLKRGVLGRTVRRIGLSQVQNTAYSQSVTGSLFGYGTVTVEVAGGPDLAFRRIDDPEAVRRTITGRIGSDGADVPGTVDQWREVLAIVRDLKRAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA8</accession>
    <name>V6DTA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4192" checksum="FB2BBAF0673D4D91" modified="2014-02-19" version="1">MRSEGPRGLCGMTQRNPTESSVDGCGANEGRGPVRSDLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTA9</accession>
    <name>V6DTA9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_14917</name>
        <name evidence="3" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076539.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72467at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="13"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="263" mass="27648" checksum="9071B36C5D0D0DD6" modified="2014-02-19" version="1">MIESLFRIDVALFLLIGVFGGAHCIGMCGPLVTMYSKQMTPQPDGGTATVDDGRAGHLTTYEVRQHFLFNVGRATTYAILGAVFGALGSVVFVTADQLTPVADLLRGTVGLAVGGFIVATGVRYVIGGSGGDIRIPGVQRVTSWLAARVHRHVNSPSIVGLGAVHGFLPCPMLYPAYLFAFASGSPTTGGIALGALGVGTIPAVFLYGTVIQSIDVTHRRRVHRLLGVVFVVLGYVLFAHGLMALGVHLPHPMFPHYQPLGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB0</accession>
    <name>V6DTB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5368" checksum="8915B966601FBEA8" modified="2014-02-19" version="1">MSNIENQLQLLGSVRVLFFRHICIPHVFSNYRFFRGFKIQDRHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB1</accession>
    <name>V6DTB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CopA N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_05887</name>
        <name evidence="2" type="ORF">BN903_191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077063.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123956at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6334" checksum="FDC369D839D2A3F1" modified="2014-02-19" version="1">MTTVDVDGMSCTGCEDNVTDALGELPGVESASADHEAGTATVEGDVDVDAVVAAIEEAGYEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB2</accession>
    <name>V6DTB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP/cobalamin adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HSB1_28600</name>
        <name evidence="1" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076267.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110160at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="14018" checksum="EE608BF75BA312AC" modified="2014-02-19" version="1">MTTVTLDVAKQIITAAEEEAAAIDVPMCVAVMDGGANLVAFHRMDGALLGSVDIAQNKAYSSVSLKLDTEAIHEASQPGESLYGIGNTNGGRIVTFGGGFPLENDDGTVVGGVGVSGGSVDEDMTVARAGVERFEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB3</accession>
    <name>V6DTB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5215" checksum="5E22337A8B3028A8" modified="2014-02-19" version="1">MCPYARCSFQNAKTILFTEKLLVAYLSIGENYRVWATRRAEIRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB4</accession>
    <name>V6DTB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Copper ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_14937</name>
        <name evidence="1" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6430" checksum="7D4425F6C8F74D18" modified="2014-02-19" version="1">MLGYRALLTDATSGEFAVIRTYPVSTVGYVLGCYWRVSRRSSRSWAFPSRWSGYTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB5</accession>
    <name>V6DTB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7897" checksum="8B967AF91D319CCD" modified="2014-02-19" version="1">MYKNDSWWKAVILSEGFRGREVNIYVWLNEDNGWTRKQKYSVKSRDDWESDRNLVDEFVEALPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB6</accession>
    <name>V6DTB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4564" checksum="B4EA520524CC1F1D" modified="2014-02-19" version="1">MGVPVVGGKAHRGVGXXXXXXXPSRRARGRSAPTAASRRRLSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB7</accession>
    <name>V6DTB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase, IS605 OrfB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_01355</name>
        <name evidence="1" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="8668" checksum="61FFC57D8C440F66" modified="2014-02-19" version="1">MWIRCSRGLQRSEEYRSEVPPRPAKVWAWRRTRRRALEQRDVECERRVFVYCSQQLERESKLNATPFRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB8</accession>
    <name>V6DTB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_03956</name>
        <name evidence="1" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076270.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="127462at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="10436" checksum="8C613DBD4939AC35" modified="2014-02-19" version="1">MSKHFEDARYYLGRATEHAKAGVAEELEPVETRVKALVGREDEEPEPEPSRLDKLQADLKRIEERAEGEAREAVASARERVAEYRGKDAAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTB9</accession>
    <name>V6DTB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
            <ecNumber evidence="2">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_00067</name>
        <name evidence="2" type="ORF">BN903_190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077062.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43299at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="300" mass="32305" checksum="58DB179558DAB6D9" modified="2014-02-19" version="1">MDTVLVTGSDGGVGGWTVDALADAGHEVVAVDRRTPPERERRDGVDYKAADLTDYGETRQLVDAAAPDAVVHLAAIPNPEDHAGSRVFANNVESTYNVFDAAGTAGARIVWASSESLYGTVFAAEDWLPDRLPIDEETPTRPEDPYGLSKVVGEEVAAAAARRHGVPAVSLRLSWVTFPGDERRREARETFDPATADPSGNCWSYVDVRDVVSAVEAAIDPETPIEGHEAVLIVAAENFLGRDTAATIEAVRGELPAECDLDGDESVFDCAKAERLLGWTPEHSWRDDVCSDETRLSTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC0</accession>
    <name>V6DTC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5914" checksum="4465A02AAE4068F3" modified="2014-02-19" version="1">MCLCLFQWGPSLSSTVIWWVRVSHAHGESISKVTNIKNTENSGGEHDYSYWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTC1</accession>
    <name>V6DTC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14877</name>
        <name evidence="2" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="224" mass="23539" checksum="75D72D4F7030F050" modified="2014-02-19" version="1">MPMSVWRRFLQATPQQCAPGSHGATDGLPVLIGYIVWTDARHAIVAVLFFVSASNYLSFFPDEDVPPETVVDILSVVYPRDVANAGSVPPGRPRVRGHVDRRRYPRRYRESTGRVERAADRIPVAKLGRRGGSDGSGNAGPTAVIGACACGCCGPLVAKVAILAAGPSVAAPLYWLFVDPSSPFASAFLVGGIVLFTGSLVYATNAVRAGSSTRPTVSGESDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD4</accession>
    <name>V6DTD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="4747" checksum="F5EF03C840C0D9CD" modified="2014-02-19" version="1">MTEEETDAGDAVAPPTAPTTSRTTWGRTGRGGAVPTAGSGSGRAATGMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD6</accession>
    <name>V6DTD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase (TCE33)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_00347</name>
        <name evidence="2" type="ORF">BN903_216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="12142" checksum="5FAD7CDAA64701F1" modified="2014-02-19" version="1">MGSGRSTPSPDTVHLVGDSVPLVLDARPIRKGDTRSEIVEDLLDSAIELVDVDRVFMDREFDSQHILEAIADRGVTYVVPKRMHTSEKAQAKRLLQRDQDRSSMALSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD8</accession>
    <name>V6DTD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4160" checksum="1D2C3FAEC4F3B62E" modified="2014-02-19" version="1">MNAGGCEQNLGSTGLKIVYCPSELRCPKAHTLFECKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTD9</accession>
    <name>V6DTD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="10369" checksum="783F01DED2EBA9EC" modified="2014-02-19" version="1">MGVPRDVLGHLVDAGIRRADPVALVDIDRLGAPRFQPQSVRFDGLGEHVARVAGAPKNATGGPRLGHTPDTGVRTFVEILRELHSYISYLMLKSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE1</accession>
    <name>V6DXE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13097</name>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="10538" checksum="2AB0E8B4E482FA4D" modified="2014-02-19" version="1">MISRNIIYSCLRTAAVDGSIGTESATDRPFYRPTASGSGMTDADASADLGSTIGALTVAFLLVTAVAGTLLGFNWTQAVLIGGFAGFMAVVSAWVTARRADGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE2</accession>
    <name>V6DXE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11996</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077549.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114514at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10354" checksum="5054F67E6513B8FB" modified="2014-02-19" version="1">MRLNGVDDRLERHQYPTTSEEIIAAHGNATVELANGSERLGDVLERFGDQTFEDAGEVFTAIRAGVCHRGVGRRFYSDRDPTTDAEDGPSPVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE3</accession>
    <name>V6DXE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5729" checksum="EE86FA84C893BA74" modified="2014-02-19" version="1">MSRALIARLDVVVHHYEADVVTEVAEAPAARRSDARCAPRSRCSLRCLHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE4</accession>
    <name>V6DXE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6048" checksum="DC40339AA7AD75F6" modified="2014-02-19" version="1">MARSVLCVSMWITCAERLREQNCQFLLNSTRLAVLTRGQRRVSAVARVVAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE5</accession>
    <name>V6DXE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8774" checksum="7DEFA3104269C53F" modified="2014-02-19" version="1">MRSLSPPVAIPSAMCPAPRARRARPPPRLSERRRRPLGLDADHARRXXXXXXXADDYLTERERAGELYEGAVDAATADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE6</accession>
    <name>V6DXE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11466" checksum="1A23943A17C771B9" modified="2014-02-19" version="1">MHWSVWCPVPASGLDGTERPRLTSDRRLRRSAGGAILISRGPERIVRQVINPSNHIRSKRNRAELNGPSPRCVLRISSNAGVVLNPVEPSAPRHAVSCRDGRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE7</accession>
    <name>V6DXE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
            <ecNumber evidence="2">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07510</name>
        <name evidence="2" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077552.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50620at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07726">
        <property type="entry name" value="ST1585-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037482">
        <property type="entry name" value="ST1585_MBL-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="28"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="304" mass="33953" checksum="B7E9CACB212EC2E4" modified="2014-02-19" version="1">MRAGEFEPVRGVDDLYIHDTGMFETDEYGAVYVYDAERPIVIDTGTGANREALFETIEQIGIGREELAWILPTHAHLDHAGGAGYLAERFPNAEVRVPEKGVRHLVDPGALVAGTKSAVEEQWTHYAEPKPVPDDRIEGVSEGDRIDLGDRELVVRDAPGHAPHHAVYHDPDAEVVFSADAAGIYVPEIDAVTPTSPPPQFDFEQCLDDIRLIEDLDPDIVCFGHFGPRECDADLIGEAKRAFVEWVERVRQKRAELDDDEAVVDHFEAASRDIDYWNPERARANTSLNTRGVLTYLDRVDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE8</accession>
    <name>V6DXE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
            <ecNumber evidence="2">3.5.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_10353</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077919.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79386at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="21426" checksum="5738E746B27C5536" modified="2014-02-19" version="1">MAFDPTETAVVVVDMQNGFCHPDGSLYAEPSEAAVEPVTALVDRARDAGASVVYTRDVHPPEQFDDTHYYDEFDRWGEHVVEGSWDAELLGDLDVRDADHVVEKHTYDAFYRTDLEGYLDAHGIRDLLICGTLANVCVLHTAGSAGLRDYRPVVVEDALGYITEDHREYAVDHADWLFGETTSRDEVAFASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE9</accession>
    <name>V6DXE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5905" checksum="FF42675FA4F35332" modified="2014-02-19" version="1">MSAEPDAPPRDRRFDPAFGDDRSAIPDATRQFIRVTVVRMGTNDARHSRSFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF1</accession>
    <name>V6DXF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_02821</name>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58840at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="294" mass="32174" checksum="9B52AB1A1A094659" modified="2014-02-19" version="1">MIGGIGITATAGCLAPFSRSDSCSDSNEGGLSLDEATATGIANECSTPLDGLPHASQVAVTDALDSERGESTSRRYYAPDPRKDFVVTGPEARYFRINTTDHDGTQTTGYEYSVEIDVDESALSDGVTVRPFTELPAHDRESLHSAIGNSGLLHAPHYTSFSVVFAYEQTGVRDRSVFIPGGATHYLEWDETLLRLTFEQQLTVKITSTTVSTELVARSPDEFKEYIGDNRGVVLDSLTSQQQDIVARAIDGTYTECKPYSEPFNALREQLSIPDHIAVLLVHYDGGWYFGHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG0</accession>
    <name>V6DXG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uridine phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_10031</name>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5052" checksum="4D0E2680DAA29877" modified="2014-02-19" version="1">MAKQPHLLVEEGDVHDIAIIPGDPGRVDRIADLCDDSEGSVARILTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG1</accession>
    <name>V6DXG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08569</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078388.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88136at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="234" mass="25153" checksum="8492DD7896203356" modified="2014-02-19" version="1">MSTWKRDFASGLIVLAPLLVLLLVLRWIYQYIASIPLIADLQPAVIPGYLEPVSRVVIAFAVFATVVLAVGYFMRTTLGRLAEAAVDDTINRIPALRVVYNASKLAIETAISGTDELQSPVYIETWPGIRMTAFRTGKKTRDGKIVLFMPTAPNITTGFVIEVEPEKIEETGESVEEGMTRVLSAGFAESAHQVPVHEEDPTEGDGTPDGYGHVRTDGTPGGDGSATDGSGSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG2</accession>
    <name>V6DXG2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDDEXK_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_06851</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077952.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92564at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021671">
        <property type="entry name" value="PD(D/E)XK_Endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11645">
        <property type="entry name" value="PDDEXK_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_5" evidence="1">
        <location>
            <begin position="13"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="17692" checksum="646E301FD805D2A1" modified="2014-02-19" version="1">MSRREQYERLGEPQKRGQTTEAIVTAELLARDVSVLEPAYDNEPYDLVIEVDGEFHRVQVKTAYDGKRDGTVEFRTRSVRTKSEGYEREGYEGKIDYFAALNVGEEDIYLVSIEEAGATTVTIRYEPAANNNRANVNWYAEFRLDTVLGRLRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG3</accession>
    <name>V6DXG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11899</name>
        <name evidence="2" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077560.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44748at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012022">
        <property type="entry name" value="UCP005295"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42658">
        <property type="entry name" value="PTHR42658"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="335" mass="37242" checksum="B08F59E3B15425FF" modified="2014-02-19" version="1">MSAPQPTVRPTDAAFLDESDPELPTELLNVPWIDPHNHAHTLSWEDRERYALSGCRSMVMVSSGYHWTPYKPVEASDIRFLWDDAVNRRRAIERNHFFEAKLSLGVHTGVRIENPDELLAAMGDYCALDEVVAVGETGVTPSQHVERWDVDEQQAVVQAQMELAADHDLPVLLHTPNTSTESKREYRDDLGVTPGYEKNAGLGTEPVLDGENPALEAVKRDVEAAGDAGLDEERVVASHADANNTAYLMAETDCYLSYTIGHSWLVGVDAADVANAIDEYGPGRIMIDTDTANVLRTDPYAVKRAIFELYRYGIDIDDIRTVVYENPRDVFGLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG4</accession>
    <name>V6DXG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_09885</name>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078372.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000026.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62121at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="316" mass="35979" checksum="184C4F33A640AD13" modified="2014-02-19" version="1">MNRRRFLAGAGITALGTITGYGGLRVTDIRPYDPALPTGESPRERIIAAARHRHAVDHRAVTKVRVLEDWTGETPYDLDIRKLWHEPSRRRHLHTLTTFETPLTNSSRLADAPDREYITPHQTLWALLHYNRVLNDSYDLPLTNVRYITDGAWLYDHDAPTPEGDAVRVSDKRSGHIPDGDYERAFEPVGRDFIRPHRTDWTRTAADDATVTYRVTGADAYAQVVPLPFAPISASAFGDCWIEVTLHRKTGRLRRIVDNRAVVIDLQDGAGERSLTYRIETKIDRYGDTRARRPAGSVNRSLESRVRALLFDLMNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG5</accession>
    <name>V6DXG5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1949 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11956</name>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1949" evidence="1">
        <location>
            <begin position="5"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5385" checksum="F260C3B8349111C3" modified="2014-02-19" version="1">MIESTGVEFEADYGQRVRFDLRVPVEEVDTLRERLNDATSGRVEIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG6</accession>
    <name>V6DXG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09261</name>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9179" checksum="9A5799AB0A787BFE" modified="2014-02-19" version="1">MSNHYVRPVDDATPEMRAEFREEYLVRNGWPTDEQLDAVDESLSVVESVAVDVDGPAAVDDSAADSAADDSAADDSAADDSTADDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG7</accession>
    <name>V6DXG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08534</name>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="17211" checksum="6ED8FEBEDAFEA191" modified="2014-02-19" version="1">MRYRRGFFPADRRSRRMRSESSTGAGDPAGSEPIWRTVTKGFPTALTHLIAAFTLVGVGIVGTGAVAADGAAELDEDVVTVGENGTTEIAVESEGVESFEVVVGNEDDSGYELRGTVTPDGDGVTRLTYDHAAAGDGGDPLTADRGGVELDGETDLGEPPLPEPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG8</accession>
    <name>V6DXG8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07420</name>
        <name evidence="1" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077563.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100319at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012017">
        <property type="entry name" value="UCP004977"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09846">
        <property type="entry name" value="DUF2073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004977">
        <property type="entry name" value="UCP004977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="14872" checksum="701DE073FE747C81" modified="2014-02-19" version="1">MPGPKANVDAADDDPDDDGVRIDMISGARMEGLTGMEKIRLILDGVRDGNIVILEEGLSPDEESKLIEVTMTEISPDDFTGIEIETYPKAEAGDQSFLDKLMGRESTQKLTVIGPANRIETLHKDENLISTLVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXG9</accession>
    <name>V6DXG9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">icd</name>
        <name evidence="7" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078375.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000026.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="33452at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00183">
        <property type="entry name" value="prok_nadp_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="6">
        <location>
            <begin position="32"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK41034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="420" mass="45976" checksum="89AFB13423228D33" modified="2014-02-19" version="1">MSYDKVDVPEDGEAITLADEETGELNVPENPIIPIIHGDGIGTDVGPAAQQVLDAAAEATGRSIAWMRVYAGGSAREMYDENLPEDTVSAIRDHRVAIKGPLTTPVGAGFRSLNVALRKTLDLYANVRPTYYIDGVPSPVKNPEEMDMVTFRENTEDVYAGIEWEAGTDGSEKVRDFLEQDMDVPDVIHDGPVGIGVKPISEFGSKRLIREAIDYALANDRDSVTLVHKGNIMKFTEGAFRDWGYEVAEEEYGEDVITEDQLWEEHDGERPEDSLVVKDRIADNMLQQLLTRTDEYSVIATMNLNGDYMSDAAGAQIGGLGIAPGINRGHGRCLAEPVHGSAPKYAGEDKVNPTAMILSGREMLDYLGWSDAADLVREAVEETIASKRVTYDLHRQIEGGEKLATSEFADAVVEQIEELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH0</accession>
    <name>V6DXH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6207" checksum="CABD890909D9D02E" modified="2014-02-19" version="1">MDTDHGGDVEEVLPPTPSFRVETRVGVWVVSGLWTAVAVLTVNTDTKNNKITTLLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH1</accession>
    <name>V6DXH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_09226</name>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077962.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101630at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10773" checksum="FE5139D81F1435CB" modified="2014-02-19" version="1">MATEEPEFADVSIGQTVYDDSGEELGTVRGVDDDGFYVSSPAGTESLPLTQARDVFGTAYVMWRCWKCGEMGEISGELPANCPSCDAPREELYYWAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH2</accession>
    <name>V6DXH2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Geranylgeranylglyceryl phosphate synthase</fullName>
            <shortName evidence="8">GGGP synthase</shortName>
            <shortName evidence="8">GGGPS</shortName>
            <ecNumber evidence="8">2.5.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">(S)-3-O-geranylgeranylglyceryl phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Phosphoglycerol geranylgeranyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C473_13036</name>
        <name evidence="9" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23404"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57677"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GGGP/HepGP synthase family. Group I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.41" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078398.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74340at2157"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047294">
        <property type="term" value="F:phosphoglycerol geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002094">
        <property type="term" value="F:polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02812">
        <property type="entry name" value="PcrB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00112">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039074">
        <property type="entry name" value="GGGP/HepGP_synthase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038597">
        <property type="entry name" value="GGGP/HepGP_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008205">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026417">
        <property type="entry name" value="GGGPS_Halobacteria"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40029">
        <property type="entry name" value="PTHR40029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01884">
        <property type="entry name" value="PcrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01768">
        <property type="entry name" value="GGGP-family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04147">
        <property type="entry name" value="GGGPS_Halobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Glycerol-1-phosphate binding" evidence="8">
        <location>
            <begin position="161"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glycerol-1-phosphate binding" evidence="8">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>sn-glycerol 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>sn-glycerol 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK41052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="232" mass="25207" checksum="7B15BA0DBD57CAB9" modified="2014-02-19" version="1">MTNPWDDWDHVLKVDPDKDLRPGETFEDVCRTGTDAIEIGGTLDVTAEKMTRVVDAAAEYDVPLYQEPSNPGVVIDSPALDGYLIPTVFNAGGPFWITGAHKEWVRIDDLDWSRTHTEAYIVMNPEASVAQLTEADCDLSADDVAAYAKVAERMFGQEIVYVEYSGTFGDTEKVAAAADALDDATLFYGGGIHDYESANEMAAHSDVIVVGDLLHDEGIDAVRETVEGAKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH3</accession>
    <name>V6DXH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07400</name>
        <name evidence="2" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077568.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55211at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="300" mass="31975" checksum="B92FBCCB853CE856" modified="2014-02-19" version="1">MFSTRSLDDDLAAVRDRYAPGSPVLDVETDFETLPPAAAEDLGLFVDALAPASYPAEWLPEAVPDLLRKHAGPAFTVGLPGDGTVVRTTQTDPPAVLVKRRAEGTPDDFLAFLIAERLVQIGCEPASGAVGGDDAASTADAASTAGDAPGLPETFLPFFGERYRDLDAAIRRPDPETGASTTGFGPADVFQVANALFDAWVGLHTREEFASWTGEYPRLFDAWEDAGDRLSGRLGELSTEVARGDTDFPSATEYACSAVKHDLDLPAPYGALDTAAYRDRGAAYAVRWTQKTFAALVDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH4</accession>
    <name>V6DXH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_01071</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078385.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119265at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14656" checksum="B3F79C3C532C0E0C" modified="2014-02-19" version="1">MWGSRGGRDRRTVTCIACGDSVLREDAREYDKEGDRWDRRDKEFEYLCADCDDGISHQPRGGLESLICSIESDGLSTEEFLGRYVDAVTSDADGPAETSDGRSRSDDDLPDRDRSDRDRSDHDRSDRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH5</accession>
    <name>V6DXH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4115" checksum="6334493CBCDE0556" modified="2014-02-19" version="1">MSLEDTVSPADPSSASAFSVGDSADSLADPPCDSLIPSLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH7</accession>
    <name>V6DXH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11606" checksum="3DDA69DD0AEA8888" modified="2014-02-19" version="1">MKRTALRTLELVIRSLPAYDLRLVAVVGQELVEHVVVRIGCATRHACHGMSHQYIYLSRVLVAANYAIERSVLSASSKKPERFGVRLVSDGFSTYHGSFFSPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH8</accession>
    <name>V6DXH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4166" checksum="AF4D44277AA05585" modified="2014-02-19" version="1">MNYRTQTATVGARLRGRIAAEERRARESVGRSEAETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXH9</accession>
    <name>V6DXH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, ATPase protein I</fullName>
            <ecNumber evidence="6">3.6.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_09443</name>
        <name evidence="6" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.24" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="346" mass="37934" checksum="9230FC325DF73BA9" modified="2014-02-19" version="1">MTALSLVDLVETPGRITSGKVWYRDPDLADEFRDADAVQVDGDHVDLRTVPQSVRRSLRGPSFSVIFQDPMSSFNPSITVGEQIAEAVEVQRRARANPRSTRSRTQGYGLGKYLLDEIVPGRDYTSDESMDRAVELLGQVGIPDPEERVDEYPGQFSGGMLQRAMIAQALAGEPDVLIADEPTTALDVTIQAQILTLLREIQAERGMSIVLITHDLGVIAEMCDRVCVMYAGEVVERGTLDSVFNETVHPYTQGLLGSIPDVDDPRARLEPIGGNVPSLVDAEMDDRCYFADRCPKAMEACLERPAERTVDAAADHGAKCVLADREYDPADALPQEYFDEDGGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI0</accession>
    <name>V6DXI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_07430</name>
        <name evidence="6" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077562.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107233at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="146" mass="15630" checksum="DE61B93EC2FBC269" modified="2014-02-19" version="1">MADESTSEPEADAAGRDAPSLLGRSLYGGVLAYMAVDGFKNNDKRVAVAEEKGVPMPDLLVPFVTGMLLVANVGIVFWRLPRAAAGALVVFFLGTTPAIHDFWTMEGKERQGNKINFLKNLALLGGAIVFLDAASERDGETESDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI1</accession>
    <name>V6DXI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10933" checksum="678D753559963EF6" modified="2014-02-19" version="1">MFCVATACFVPILVARSSSTNVASRARPDSTGITRNRRRILHRVGSASVTTIVGYKCFVWPPDVCERPSWPVAGVRRPFSRLRVMEAYGWFAVDCGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI2</accession>
    <name>V6DXI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07333</name>
        <name evidence="2" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077577.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122063at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9433" checksum="B47E179B57211AF7" modified="2014-02-19" version="1">MSGDESRTPEPVDADITAEACGRCSMSTVVGAVADDQSSEERAERDPFADERIEVDESSLRRISPAGYLGDLKERINGLGRRIAYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI3</accession>
    <name>V6DXI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_09136</name>
        <name evidence="3" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078010.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81806at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="23924" checksum="E32FBFA2905B10E0" modified="2014-02-19" version="1">MTRFSDEDRERIRGELVEAGRELFTRHGFERTRIKDVTEAVDIGTSTFYQFFDSKETLYVAVLKRERDRLIERVDAAVADAATPREEVRTMLETLFDEVRSDPLISRMIVDNELQALLDQLSESERESLAADTPGEPLGYADRWVEDPSFRFDDPDLVRDAVTSLVFTTRSQELVREPGTTTDPTRVDRALIDTIVDGLFVDGAGEAADAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI4</accession>
    <name>V6DXI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_13454</name>
        <name evidence="3" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078395.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="127683at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="10373" checksum="9A8E5FD8FEDA23B4" modified="2014-02-19" version="1">MRLGVLDMIGLAASLIFALPLANYAIVRVIAGEIALGSGLLVVAVAMVVLPQYFLDPAQILRRLLSGLLPRQLRGDDAAAPETEDGSQSVAVGSDSDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI5</accession>
    <name>V6DXI5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartokinase</fullName>
            <ecNumber evidence="7">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C467_11869</name>
        <name evidence="10" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077566.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20371at2157"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="260"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="336"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="393" mass="41852" checksum="BA10F340FC666772" modified="2014-02-19" version="1">MRVIAKFGGTSLGSGDRIERAADSVASAVAAGHEIAVVASAMGSTTDELLDDITFETDDADRAEIVSMGERTSVRMLKAALSVRDVEAVFLEPGHPDWPVITDERGEVDVAETKRRAQKIAARLDGVVPIITGFLAEDHDGNVTTLGRGGSDTTAVMLGNYMDADEVVIVTDVEGVMTGDPRVVEGARNVGQITVDELRNLSFRGAEVVAPSALSYKDEGLAVRVVHYQHGDLLRGGTRIEGEFESLIDMREEPLACLTIAGRAIRNRPGILSELSNALRAEEINIDAVASGMDSVTFYVDVDVAETAEALLHESVVTDEALSSVTVADPIAVIRVTGGELPNQSGVIQDIIAPIADAGINIIDLITSATSVAVFVDWDDREEALEIVQQRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI6</accession>
    <name>V6DXI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenine phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_06674</name>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078406.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000028.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97021at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="92"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="237" mass="25401" checksum="8667C6E6D4087F28" modified="2014-02-19" version="1">MNRAEKAALQLQAVAVLRMLKETRTYEELSEVTGLPAGDLNRYVNGHVLPGTDRASEVVESVGREALADELVARVEFDDEGYVDNSGVVFDQSFLDLVAPVAAETFEFESPDVVLTAATDGITLGAAMASFFDARLAYAKKSKETAVEEFIESRQRLASGIELTYYLPASAIDAGDTVLVVDDLIRSGETQELLLDIALQGDADVTGVFTLIAVGDEGMDRARAITDAPVGALTTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI7</accession>
    <name>V6DXI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5519" checksum="8B1DCAFE5B682144" modified="2014-02-19" version="1">MKPSIAAGFDKTDSAGLLRPSQQTRDSRVAVESIKTPHRGVGPGGQNTPVNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI8</accession>
    <name>V6DXI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07268</name>
        <name evidence="3" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003847">
        <property type="entry name" value="Put_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02697">
        <property type="entry name" value="VAPB_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7511" checksum="A0EFABBE34F648CE" modified="2014-02-19" version="1">MYDRLRARKRDDESFTDLLDRLIDETGGDWRDGFGSLSSGEADSLREAADRSRQRFDRAESRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXI9</accession>
    <name>V6DXI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
            <ecNumber evidence="2">2.1.1.197</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07375</name>
        <name evidence="2" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.197" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077571.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65428at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102130">
        <property type="term" value="F:malonyl-CoA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="43"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="225" mass="25413" checksum="BE6F44A1186B9D2E" modified="2014-02-19" version="1">MSVREEFDEWAATGKDRGMEDRHWHTAKHVLARMPVEAGDDVLDLGTGSGYALRALRERGISRGYGLDGAPEMARNAREYTDDDAVGFVVGDFDALPFADDSLDHVFSMEAFYYAADPVNTLREVRRVLRPGGTFYCAVNYFAESETTHEWQENISVEMTLWDRAEYREAFREAGLYVAAQDAIPDRETEIPDAEAFPTDGYETREAMVDRYRTWGTLLTVGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ0</accession>
    <name>V6DXJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5597" checksum="11A618CAC8FE2170" modified="2014-02-19" version="1">MIISTEPIRCKLRSTRTAPKPQPGGGRTLAALLTLSRCSLVAVLPSSSERGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ1</accession>
    <name>V6DXJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7796" checksum="D5DFCA4F17949869" modified="2014-02-19" version="1">MSPTRSQPHSTSHLPSLVGRLHFAPATDSLARCSSRPPSAARSEARATALFFIDGPRRRSDLFKCTLTDSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ2</accession>
    <name>V6DXJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_12186</name>
        <name evidence="3" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004599158.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000029.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38948728"/>
    <dbReference type="GeneID" id="55594640"/>
    <dbReference type="GeneID" id="65214611"/>
    <dbReference type="OrthoDB" id="122478at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7092" checksum="726961ACD8456FD9" modified="2014-02-19" version="1">MATGKVDFFNDTGGYGFIETDDADDDVFFHMEDVGGPDLEEGQELEFDIESSEKGPRATNVVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ3</accession>
    <name>V6DXJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_04510</name>
        <name evidence="6" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01068">
        <property type="entry name" value="globin_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039379">
        <property type="entry name" value="Protoglobin_sensor_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="239"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="510"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="471"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="575" mass="61835" checksum="8EC932A8A65BFD32" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ4</accession>
    <name>V6DXJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_11791</name>
        <name evidence="1" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077575.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122889at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8688" checksum="0C1BA8A395E4AAD3" modified="2014-02-19" version="1">MSEVLRVEAGELAVDELIDALNDGRRILVDVEVAGASHEVALRYDGETYHCDTPTNLHRHADESGMRGCIDQMGYAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ5</accession>
    <name>V6DXJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease NucS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nucS</name>
        <name evidence="3" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002793">
        <property type="entry name" value="Endonuclease_NucS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38814">
        <property type="entry name" value="PTHR38814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01939">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="227" mass="24402" checksum="294EE6104DA5BD8A" modified="2014-02-19" version="1">MLKPDGAALVHTDEGRQPVNWQPPGSEHRAAVRDGRLRVVSTRSNPDETLTVRFSDVHQLSAMAVTGGRDLDLHGSEEDLRTRILERPDLVESGFEPRETERPSSAGPMDIFGVDADETPVVVELKRRRVGPDAVGQLARYVRAMEEELGVGASAAAADGTADAENDPDIENDPESDLDAENNADPGNDGVTAVRGILVAPSITDRAAERLADRGFDHVALEPTPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ6</accession>
    <name>V6DXJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_15795</name>
        <name evidence="1" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="16792" checksum="0A1B9074D4C4D93C" modified="2014-02-19" version="1">MRVRNQKQFLHPALSYADHDMMEFVFARRVSTPSVADVERLVEFAHGVADDRVDGHEEHYGTDVTVVLVADRVPDDVADFVEGFHDRTLLKFGYYGHYEVNLVVVAPDRESLAASESADTAAAFRLWEAVDEPDEGLFSRFAKRFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ7</accession>
    <name>V6DXJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_09428</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078404.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000028.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6658at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="113"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="547" mass="59090" checksum="85FC0D497D007953" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ8</accession>
    <name>V6DXJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="199" mass="21957" checksum="81AC779CA65764FC" modified="2014-02-19" version="1">MFNSGESTPSNDPVAAAVRIGSRYRSGVSESRSSRSVTLGGRLRDGARILAGFDRRRLVGDIRAAGRRLKGEAERDADEKQAHDRGGSGGGEGGGHERSIRKFQLKVFRSGAPRPRLRERATRDRKSGFEAGSCPTASVVGRGARFRRRFGLLRLTRRLVDRVDVGDLVVAFVRLIGPVTRLDFRPRARLVVMMAHDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXJ9</accession>
    <name>V6DXJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_04023</name>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="9248" checksum="64799897417E4058" modified="2014-02-19" version="1">MPTGSALSLFGTRIGTATEHDAGTEPGAPRVEWAPVDVLANGERVVGLSLFAARGGRFGVKVVCPDATFEVGASVTVEVVPSDDPVRLGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK0</accession>
    <name>V6DXK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5038" checksum="1B964A2BD2803F1B" modified="2014-02-19" version="1">MRCGAGIEGAAARTLLGDVSTAASNASEERNEPRESSRLGLRRSCSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK1</accession>
    <name>V6DXK1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="2">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rrmJ</name>
        <name evidence="2" type="synonym">rlmE</name>
        <name evidence="4" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.166" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078409.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000028.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105478at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="3">
        <location>
            <begin position="198"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="260" mass="28477" checksum="939C738447D01952" modified="2014-02-19" version="1">MSGKDDYYNRSKQQGYRARSAYKLKQIDEEAALFDRGDTVVDLGAAPGGWLQVAAEEVGEGGTVVGVDLQRIDEFDDHDVETIRGDMTEERTRHYLREAVDEGGADAVVSDMAPNMTGEYNLDHARSVHLARQAFEAADELLASGGDFVVKVFQGEDLDAFRDDVSEAFQYVRTVSPDASRDASSEVYLVGKGYTRSPVAEGDRVEVTVEEEGDEGDGIAYVDGYTLFVDGDVGETLTVEVTDVKPRFAFAERVDADETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK2</accession>
    <name>V6DXK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="4830" checksum="798AC2A8D1243EAC" modified="2014-02-19" version="1">MSGRRRGFPATRASSRDEPGGTAGVGGVSYRNANPTTPITLPSHDCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK3</accession>
    <name>V6DXK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5265" checksum="8D6C5E08527E77D4" modified="2014-02-19" version="1">MRGPRAATEARTRDAETRFPEPESLDSCQAFSRSRRCSNSELFTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK4</accession>
    <name>V6DXK4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">V-type ATP synthase subunit I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C472_08731</name>
        <name evidence="12" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078014.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14889at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="PTHR11629"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="605"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="670"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="302"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="79"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK40601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="737" mass="79182" checksum="15146CF4F0BAA438" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK5</accession>
    <name>V6DXK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Succinylglutamate desuccinylase/aspartoacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06565</name>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="9257" checksum="8EF52440302926B7" modified="2014-02-19" version="1">MLDAGGREDVSVFWLRERIPKPAADTYEVFARNFERVESGERFAAADGEPLLADEPFYPVLLSPNGYRDQFGYVADRVGTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXK6</accession>
    <name>V6DXK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArCOG04150 universal archaeal PUA-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07664</name>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078413.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000029.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="85279at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022430">
        <property type="entry name" value="CHP03684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016437">
        <property type="entry name" value="MCT-1/Tma20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22798">
        <property type="entry name" value="PTHR22798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005067">
        <property type="entry name" value="Tma_RNA-bind_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03684">
        <property type="entry name" value="arCOG00985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUA" evidence="1">
        <location>
            <begin position="78"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="160" mass="17174" checksum="13FADDAEF7E5D3D9" modified="2014-02-19" version="1">MEVKSRHHLRSDEITAIREAVADHLGVDIDGETFEFVEFVDAGYELVLVDGDPAVFYVDDDEPFLTVRGANDFDPETGVVTVDAGAISFVSDGADVMRPGIVEADPEIRGGDLVVVAEETHGKVLAVGRALVDGDEMVGDSGKVVESIHHVGDDLYEFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL8</accession>
    <name>V6DXL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08525</name>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="196" mass="20191" checksum="9E02EB7F06D31357" modified="2014-02-19" version="1">MLADKASVDVGDDVLVYGATGGVGHVGVQLADWFGATVTATGSTEAKRSLAADLGADATVDYTETAVESYVDAHAGGVGFDLVFDPVGDDHLNTAFEAVRPYGAVVTTESSDADGVDLSPMHATSLSLGVVLVIHPVLAGNGQERIGRELETIAALVDKGVVAPHVDDRYAFADVADAHRRAEAGDFVGKLLLVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXL9</accession>
    <name>V6DXL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CTP/GMP synthase operon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11023</name>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078436.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000031.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106416at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="14205" checksum="71D100066A5E8D1B" modified="2014-02-19" version="1">MTDQIIAVVAGPDERGLGEELAALGVAIARIDGLVTAEKLEAAGIADADLFVLTDVEEATGIPIAKELNPDVRIVTYASRSLPEFVATVADLAVDPDLLGPETVAEELLADDETDDGEPSEDETDDGEPSDDESNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP10</accession>
    <name>V6DP10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15709</name>
        <name evidence="1" type="ORF">BN903_172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075869.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115780at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8300" checksum="AFCCEF35E33C4AE5" modified="2014-02-19" version="1">MANSRRPIAPAEKNVLDHLEELGDTDPLTRETAITHLEDQKIKPADARDIIEQLLLKGYLYEVGDEIRIPPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP11</accession>
    <name>V6DP11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C470_04335</name>
        <name evidence="3" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12299" checksum="A509D8D31DC72A80" modified="2014-02-19" version="1">MTAFLESNGIAEETTVVICGDSKSWFAAYPYWQLVYYGHPDVQIMDGGRKYCWNTATRPRPSLSTHQTLCTATRPMGQLGRRFGQANGRASGAWNGDEAGRRVATRRIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP13</accession>
    <name>V6DP13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_2990</name>
        <name evidence="2" type="ORF">BN903_179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075873.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119976at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="11015" checksum="5E187BD74F6FA217" modified="2014-02-19" version="1">MAEIVSTNDTLGGAPRIEGRRIGVHHIAKRVLDAGESPEQVAADYDLDIADVYRALVYYYDHVDEMRKIQAKRQSVSDELSVVRGPEDLDTTTQSEPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP15</accession>
    <name>V6DP15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4088" checksum="BAA4CB768E4D6ECC" modified="2014-02-19" version="1">MGARRVDHGLVESLVVIDNGGALSPADGHYQAMAARSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP18</accession>
    <name>V6DP18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15689</name>
        <name evidence="1" type="ORF">BN903_184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5821" checksum="C53555466F183668" modified="2014-02-19" version="1">MTSNNPEAVRGTCSFCGERVTGRHAIIHYETAGGEPGMWAECPGCGEIVDPINAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP21</accession>
    <name>V6DP21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5326" checksum="7500E03791BF7F73" modified="2014-02-19" version="1">MTGTEILVGSPPSLQALAVIAIVLLEAVLLYVGYGTVEDAVGAIVLDRLAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP22</accession>
    <name>V6DP22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C442_02971</name>
        <name evidence="1" type="ORF">BN903_189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15298" checksum="AAE20353C73C7E9C" modified="2014-02-19" version="1">MFGGEELFSFAGVISVSIEAIISDTHDYVTKRQLITMLDNLTGIHNVPLFHLTGHEAPIIHSPMEPAEKNPYRWEPLTEEIIQIAPVAEGDENFWLNLVGLHNGDVVSEWMIPGDEVMESLEPGFDVSSGDFEQYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP26</accession>
    <name>V6DP26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="11231" checksum="90BD8612C26383F8" modified="2014-02-19" version="1">MIRHLCLIWRCLTEPNEHDRPATGVDTRCLAERDTPDEPFYDSWARHRDHGWDRRLRRKCSDKRTLIGLLRGVDDRPDQKMCVGGRPPNPPSVSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP29</accession>
    <name>V6DP29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5435" checksum="47597DFC4BA5B255" modified="2014-02-19" version="1">METLDFDDTPNVPTIFQTDERILEAISNLYIELEEYRHSIIHDALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP31</accession>
    <name>V6DP31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4940" checksum="8C4CCD8B285D389A" modified="2014-02-19" version="1">MFITNYSQTGFSYIPDKNVVFGILHYEVLLQLPQYCLVEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP36</accession>
    <name>V6DP36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="6047" checksum="3B9DA3FD9C5AA68A" modified="2014-02-19" version="1">MCVESRADRSEFDEDFVKYVTLSFARFRRRFTTAALHPLVDELLNFARFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP39</accession>
    <name>V6DP39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075886.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="7861" checksum="8B6DFD5275F5D425" modified="2014-02-19" version="1">MSFQDSKAAINDRLLDLTKAIDHENEAARLQCGALAGALVGGWSIAASIEFGYSPLIGASILTIGVMAGLAARIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP42</accession>
    <name>V6DP42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_2924</name>
        <name evidence="2" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075843.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78451at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="201" mass="22317" checksum="EC6547BB470481F1" modified="2014-02-19" version="1">MRGKISVFRPIEAYAEAGSSRTHGVVAIISFCVFVGTIVFGFVPVTREIEVSGYSTADLQEATTRADVDTILQAFEPVMDSVVLLSVLDYLFIVAGFFLFFSLHSLVMKRLSFDDRLVMVPKLGMVLTICSRLLDALENLWVILIYSNPDSYRIALISLMNTTQSAKWLVVTIEYPTLGLAIALVVLVRYTSLFDGKTSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP44</accession>
    <name>V6DP44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075891.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="245" mass="27632" checksum="E64A203786309AAA" modified="2014-02-19" version="1">MTYETSESTKDVEAVEQAHDELATEHGRDNVLVMEGSEGEIVALIGDQMGFVEPNDIQTYEYVQSRVPDHGHQIIREHRGSVLQEVMKLVNSELKYQRSEVRETYNSEIFLCCTGCEETFAHLGEATEHVQKAKDGELDTGVPSVIVTEPVFPDLDANTSRWVTCELKWDDSEEVFVNEQADIQWEIDEDAVDDSTYRVKDSDEEHSCLSDAMHAALEEAGHEIAEPKVEFRPSDTETPEWGGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP45</accession>
    <name>V6DP45_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hmuk_3249</name>
        <name evidence="3" type="ORF">BN903_202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="28"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="40"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="404" mass="44919" checksum="224985CF60EEAF8E" modified="2014-02-19" version="1">MDEDRIVGREEQIQSYVTLLQSLKTGDTPPDILVYGPSGTGKSLITHRVASEFQTVLAESGKSLAVIELNCQWLNTNYQAAVELAESLPPEAGSITVQGKSTQKVLKEFFKRLEENFDASLVIVDEVDHLVNPVDNTDEPAYSSLLYQLSRAEDLTDIETLGVIAITNAPDFVEELDPRVDSSFNPRDIVFSDYDANQLRQILYRREDAFVEGVLSDDVIPYVAALAAQDHGDARKAVDLLRTAGALALDEDAEKVYKHHVDRAQEEVERDRLLEQANGYSSGKKLVLFATAAVHAWSSDPIDSVPNPVMQQVYSFMCDITEFSEKSQPTLSRYVDEFEQGGLIETSHASKGVSTGVYRQIKMARSSELLVETLSENDSSIHDLLDDRELISSVVDTKLNEFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP47</accession>
    <name>V6DP47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="133" mass="14529" checksum="4D4B2F68CD0AB4AF" modified="2014-02-19" version="1">MNRRQLFLSTTAILTVGISGCTYDTDTPQEPHCKGTAPPTIFNEDDQRYDIDVLIEEDGETVLTEEYSVGQSNGDDDQTQIDVELEAETTYSVTISLSGTEYEPQQIEIPNGGGLAITIEDGEPTVDTYPACD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP61</accession>
    <name>V6DP61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ring-cleaving dioxygenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HacjB3_15040</name>
        <name evidence="2" type="ORF">BN903_146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="9042" checksum="33A1BEAD5F884CA9" modified="2014-02-19" version="1">MAIINVDHVAVRVTNLDRSLSFYHELLGLPVRDREVVCKRYIPVRIEGSYGLNHYKQALERITTSSSETIQPERRSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP63</accession>
    <name>V6DP63_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075909.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12477" checksum="5D659AE489CF5DD8" modified="2014-02-19" version="1">MGVEDLEKVSYHIGVYEVVGTGMGMSLPTVLSHLSGLIEIHEDGNIPTHGGDEEFLKAITLNERFDHDCYFALQTLYGNMIYDQIKKDRDAQTAESGSEWDWGIAESPSQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP65</accession>
    <name>V6DP65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14637" checksum="107E852FAB3D6330" modified="2014-02-19" version="1">MRGPRDGIEPSTASCVLREFAECPECGRGIDPDVTDGLYEDRDVIWTNNRGRKSAAHTCENCGTELRMFVEEKAFGRIGPSQLPENAEDWEEVIFIPIEDSANYLVVNTNQFWVTPERPQPDSSKEQTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP66</accession>
    <name>V6DP66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C462_00766</name>
        <name evidence="4" type="ORF">BN903_151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075858.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129474at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK37951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="9493" checksum="1C713EEF91FB7C1A" modified="2014-02-19" version="1">MGAPDFSGRDVVKALTKNRFAIVDRTGSHVKLRYEHPTNDDDVRIVSVPQHNRIRTGTLRNIADQSGAEDFEKWCQWIDRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX0</accession>
    <name>V6DSX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08115</name>
        <name evidence="1" type="ORF">BN903_296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="8792" checksum="493239E55206BD59" modified="2014-02-19" version="1">MFAAGHLLVASGDRVVTPAGRDADTLVVRPRSIAVAVAAGFLLHASQAPAFTPFGLTPTGVNRVLAIGGVAVGLWSLAVRRATRSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX1</accession>
    <name>V6DSX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Hlac_0469</name>
        <name evidence="5" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076995.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="156"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="365" mass="40556" checksum="AD30E8E4A3D12A5F" modified="2014-02-19" version="1">MTGTDRRDEELRRYEAILDSIDDAVYAVRPDGTIAYVNDRYAEMKGAGREELLGTQIYDWVTEEAAERARAVRREMAAGERDDGVVEYEFLTADGERFPVEMRFSFIAGGGDDHEPGDEAFDEFDRVGVIRDVSDRKRREEALREKNERLAEFASIVSHDLRNPLNVAEGRLDLAREECDSEHLDHVARAHNRMNVLIEDLLTVARDGEDVDETERVPLRGFVEECWEGVETADATLRVETDRAVRADRSRLRQVFENLARNSVEHGSTGSRTESGDSVEHGSESVTLTVGDLDGGFYVADDGPGIPEADRERVFDPGYTTSDGGTGFGLDIVEAVATAHGWDVRVTDADGGGARFEFTGVDVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX2</accession>
    <name>V6DSX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_17248</name>
        <name evidence="3" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8143" checksum="642DA30FE66E4AD2" modified="2014-02-19" version="1">MLMTGVKTVIGAVRFLALFVVYVTALTAMGVIRVGRAASRRAVGLVSRSDPAPGRTSDVDVTGSSHPAADGDGIEESASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX3</accession>
    <name>V6DSX3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pstC</name>
        <name evidence="11" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076983.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37194at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="82"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK39266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="311" mass="33244" checksum="1D4D27135E6A33D5" modified="2014-02-19" version="1">MSSESNEAKSLQRSGFVVRKERFYGRLIAACAVLTIAVTVGIILALSGRAFSFWSQISPVAYFTGTSWSPVIARNYGVLPLISGTLLVTVFSALIALPIGLAAAIYLSEYASDRARSILKPALEILAGVPTVIYGYMALVYITPFFKGIFPSLRTFNVLSASIVVGIMIIPMVSSISEDALSAVPDSLRQGGYGLGSTKFDVSTKIVVPSATSGIVASYVLAISRAIGETMAVTMAMGMSPQMPYFPDVFRNLAESGQTITAAMVQIANADSLGSGPTYEAMFALGMTLFAITLTMNVLAELVRRRFREEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX5</accession>
    <name>V6DSX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6808" checksum="C1708EE5F2BD4741" modified="2014-02-19" version="1">MNSVSYGILRYAALLVAIWTIFFVVLYMTGRRSLLYVTVNAVISHNALYYIYDIRNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX6</accession>
    <name>V6DSX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="17056" checksum="73DBD0F5F5AD54DB" modified="2014-02-19" version="1">MNSNVPQAPTRQESGDGPKTITRDSNRRYLSHSELGDTDSHGRISLSVSGMAVLLATKFADALTTGVGLAYVPAVYEVNPIARPVFEGLGITDGLLFSSIAVIVVIVTVTEIAALAIARRRRDGHLAPVVRAVGYGLPSLLFAAVAVRNAAVLVEAVEPLGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSX7</accession>
    <name>V6DSX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_17273</name>
        <name evidence="2" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="235" mass="25218" checksum="09B3E19745DAE198" modified="2014-02-19" version="1">MTPTDQRGSRRRPKNTCYWNDVLGLMRSWFPATSAPPPRLEATIDRRHLRRLFAPVAAVDGPTELAVADDGLVAASVDDAMVTAVQANLHRTLCDRYDATPGTVGVDATALADVLAAEGADGPATLGCDPDEETLTLEQSAFVHTQAVETDASVELPHVGDPPQGATTYHHGDALADALDYFEDRTEVVALGYDEVTDAFYVEPATTASQTATADTRYRRPRADLPARSTPGRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY2</accession>
    <name>V6DSY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6391" checksum="2FC7901A1FAE69DB" modified="2014-02-19" version="1">MAGDPRSTDRRRARRLARQRRRSGIRSIARDTTGRQSTSRLNGRGIWWLRLSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY3</accession>
    <name>V6DSY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5371" checksum="C585238C28BD4AB2" modified="2014-02-19" version="1">MVEGCRDAGICLFTLSTNQTRHAQNPVRKDAVSSVLREAKTQEARTAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY5</accession>
    <name>V6DSY5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 6 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="32"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="224"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="40"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="340" mass="35978" checksum="CC87F7E4CA577B43" modified="2014-02-19" version="1">MQDLVQDALDNAEAEKRDMDVDMEDDEFGDPRIVIVGAGGAGNNTVNRLYNIGVDGAETVAINTDKQHLKMIEADTKILVGKSLTQGLGAGGDPKMGERATEMAQGTIKEVLGDADLVFVTAGMGGGTGTGAAPVISKIAKEQGAIVVGMVSTPFNVERARTVKAEEGLETLRNEADSIIVLDNNRLLDYVPNLPIGKAFSVMDQIIAETVKGISETITQPSLINLDYADMSTIMNQGGVAVMLVGETQDKNKTQEVVNDAMNHPLLDVDYRGASGGLVHITGGPDLTLKEAEGIANNITERLEASANVIWGARIQEEYKGKVRVMAIMTGVQSAQVLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY6</accession>
    <name>V6DSY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal peptidase I</fullName>
            <ecNumber evidence="5">3.4.21.89</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C457_16362</name>
        <name evidence="5" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077004.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84567at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="388" mass="40405" checksum="089E79BA90464706" modified="2014-02-19" version="1">MELRSSLGSVATLALVAVIVAMLVGQQLGQPILFGFVVTGSMSPTLEPGDGFVAVPPVLADDIEEGDVVTFDARELQGGGLTTHRVVGETDEGYVTRGDANPFTDQDGDEPPVQESQIVSVALQFDGELVVIPSIGTVALALQGAFGAVMGVLSGLPGGDAVADGNVETLMVGGGVLLLLYSFAADLLGSDRGGRDRSRSRRGATRAGLVLAVILLLILVPATASMVIPSGVNEITVVSSESPSSNPTTIERGGSQTVTYNISNSGVFPQVAIIEPASTGVEVAETTHWIWRGQSAGTTATIHAPDETGVYYRSISERQYLGLLPLSVIVALHAVHPVVAIAAIDLVIAVVVTVVFALAVGFQPLRFRDTGRDTSVVDTVRRTVRKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY7</accession>
    <name>V6DSY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C488_20262</name>
        <name evidence="2" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077015.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116493at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="17062" checksum="5A1819D23521FFC8" modified="2014-02-19" version="1">MSDEKPIPPSEWETIVANVPLVSVDLVVEHDGGVLLGKRENEPAKGEWFVSGGTVLKNESRTDAVHRVAKEELGEPVVIDKCLGTYEHFYDTSEIEGVDSKHYLATAYRCHLEHAEPVFAGDDQHSALDLFYPPFEGFHPYVERYLDELEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY9</accession>
    <name>V6DSY9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PLDc_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C473_04179</name>
        <name evidence="8" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="7">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5083" checksum="FB8074D9C1CE2698" modified="2014-02-19" version="1">MLIAWTYSDAQNRSDHPPVLWALVVFFAPLLGILLYFIIGRNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ0</accession>
    <name>V6DSZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20841" checksum="923BFCBD910E6B65" modified="2014-02-19" version="1">MSPKWRVCELFVRWELIAAISRSFSISVTSSTSVNFATVYRSDAPLIPPPTITRSVSDMRGESSRRQTTSPVNPFTIHSRNRAVERLQTSINYTTIVEISREFSTGSIASFPRLLTRLVRSDTALGRLRTALVRRRCGAAVRSSRRTRRGRRTRGTRRGRRGPGRTGRRARSGRPEGRCRGGHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ1</accession>
    <name>V6DSZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type glutamine/glutamate/polar amino acids transport system, ATP-binding protein</fullName>
            <ecNumber evidence="7">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C463_06612</name>
        <name evidence="7" type="ORF">BN903_320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076405.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71950at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="242" mass="26213" checksum="11EA6786323E2D12" modified="2014-02-19" version="1">MTGPLVEFDGVDKSFGDTQVLYDVDLSVDEGEVVVVIGPSGSGKSTLLRCANRLEEIQGGDIRLDGRSVIETNINEIRQQIGMVFQSFNLFPHKTALENVALAPEKVKGEPEAEAKEAASELLDRVGLADQAESYPGALSGGQQQRVAIARALAMEPKTMLFDEVTSALDPELVGEVLDVIEGLAADGMTMVLVTHEMGFAREVGDRIVLMADGRVVERSETESFFEEPATERGQQFLSRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ2</accession>
    <name>V6DSZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spore coat polysaccharide synthesis SpsK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Halar_0603</name>
        <name evidence="3" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077020.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96034at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="18187" checksum="E70F6C61B143D19C" modified="2014-02-19" version="1">MIHDLEVRDLQVNPDERGHLVEVFRDDWNEYDIDPAMSYYSMTYPGIIRAWHRHLEGQNDHFVCPQGRIKVGVYDDRDDSPTQGELNTFVIGEHNQKLIHIPGDCWHGFKAIGNKPSLLINYPTKLYDYENPDEERIPYDTDRIPLDWEEPPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ3</accession>
    <name>V6DSZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_17238</name>
        <name evidence="2" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077007.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90412at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="173" mass="19318" checksum="D8BC7743D091C408" modified="2014-02-19" version="1">MFPIEHCIVAVIPIIAYVLVRDRDVPTGGFLAIVFVGSQLPDLVDKPLAHQFGLIPSGRVFVHSLPVAVPILCLAGWYAWRTERLRAGGAFAFAYLSHIVADNRRVLSLPNPTLSDDMLWPFRPATPRPDVPYWAGEASINVRLWTLFSAVVLAITVYYLYRDINEQLRSSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ4</accession>
    <name>V6DSZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_02600</name>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
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    </organism>
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            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
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        </source>
    </reference>
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            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5183" checksum="CCD6E18180671678" modified="2014-02-19" version="1">MDDHSHEPDPDKRVTAPMQAFGGREVGIGAAVTLVGLLLAYAVPFLATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ5</accession>
    <name>V6DSZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4447" checksum="F50FFC1B998CDF6D" modified="2014-02-19" version="1">MSALRLPADLYILVTNYTLTDWRFADLAVFSSGDRRSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ6</accession>
    <name>V6DSZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gfo/Idh/MocA family oxidoreductase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BRA0403</name>
        <name evidence="2" type="ORF">BN903_325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4502" checksum="0842821EB35547E4" modified="2014-02-19" version="1">MNGHRVEKTQPDGGSRGLGGDPRSVIRSCVSSGSGCGIADSSARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ7</accession>
    <name>V6DSZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_2140</name>
        <name evidence="2" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="532" mass="58413" checksum="CF929AEEAAB08E23" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ8</accession>
    <name>V6DSZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_17253</name>
        <name evidence="2" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="170" mass="18839" checksum="C4E27C7A50B1710A" modified="2014-02-19" version="1">MYGSAKLADEALISTFAHSYGVQSWVFRFANIVGPRQRGNVIPDFIEKLDADPTELEILGDGRQEKSYMHVSECVDAIQHVVETADDDLNTYNLGTRTTTSVTRIADIVSEELGVDPEYSYTGGDRGWTGDVPKMRLSIEKLAALGWEPSIESDTAVRRAARQLIDEIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSZ9</accession>
    <name>V6DSZ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_02161</name>
        <name evidence="3" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="158"/>
            <end position="181"/>
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    </feature>
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        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="24574" checksum="3B49B41A25373481" modified="2014-02-19" version="1">MTGLYDTSSVRGPGALDYRTGASDTARRRRRTAAATGRMMSLTGQEKYDAPEKDELYDLLSSHRRRYVLHYCKQTEEPVTLSELAEQVTAWEHDKTVPEITSSERKRVYTSLQQTHLDRLENAGLVEYDGDEVSLTSDAKGLDVYLDIVPPQSISWGVYYLGLSLLAGVVLGGVWVGFVPTETVPELGWAGLVLVAFLVSSVAHVVQIRRNRLDQFERPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT90</accession>
    <name>V6DT90_9EURY</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Halorubrum</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="54" mass="6032" checksum="62844F1626C540A3" modified="2014-02-19" version="1">MRSPSRSTSGTFSSTCRRHSDDFLAVVFLPLLGFGPFLSRLLWIQRSGTVTLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT91</accession>
    <name>V6DT91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5407" checksum="D82400D773A3A65D" modified="2014-02-19" version="1">MRGGNRRGSREAGAGDVSTAGANKVSDEEHNERAPASRLGLRSGSYRSVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT92</accession>
    <name>V6DT92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077050.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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            <end position="39"/>
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            <begin position="46"/>
            <end position="66"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="16413" checksum="2F7AC8A0783711B9" modified="2014-02-19" version="1">MASSPSDAPGDLTGSVGSQLARDPLGVAGLLVVFGAVLATGTGRDAVLAGVLLCVALLLPASLAFVVGQLALSVAVTVEDRIAVGVAQLALLVVLTQPARDRSLPNAVVGTLAAYAVLLGVVAVGLRESHFAAAGLLCLAVALGTYLARRLTLVRLGLVGAEPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT94</accession>
    <name>V6DT94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">BN903_165</name>
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        <name type="scientific">Halorubrum sp. AJ67</name>
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        <lineage>
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            <taxon>Halorubraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4465" checksum="346C0FE26B522DAE" modified="2014-02-19" version="1">MCHRIHIVSVARTRLTVDDRKRADHRLPRTHPATTAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT95</accession>
    <name>V6DT95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="1 2">
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            <taxon>Halorubraceae</taxon>
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            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4274" checksum="206B0953F12F4793" modified="2014-02-19" version="1">MRSSSSVRLSILDPTVEVAGRRSVAHHSMTRCDSTRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT96</accession>
    <name>V6DT96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-galactosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_16139</name>
        <name evidence="2" type="ORF">BN903_208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="281" mass="30282" checksum="4673EC1F1E280BA6" modified="2014-02-19" version="1">MNERRAGATAVTYDPDGHEITVADDAGDVLAGTVRATATDRNDAGVRIAEVSLSTEGGGVTVTPTVENAGDEPVRAGDVTLAFETAFGADARIYRHGYQSWSSTGTLPVGERFPAEDPDNAPMMNDLAASTDDRVSSYLTGLVEGDRSLTVGFLEHDRYCTRFEVDDDADGVAALRAVCPLEGARLTPGERLELPPLWVDADRDLRAGGGRVGRPRRRADGRPGARDRADRVVFVVPLLHRRHRGGRAGEPRGAPRVGDSGRRRPDRRRVHGGVRRLAVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT97</accession>
    <name>V6DT97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4728" checksum="77496BBEBCCB9375" modified="2014-02-19" version="1">MNSTDRVLICHSILSVVMGLLVQNVRSTRTNVVLSDIAKTDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT98</accession>
    <name>V6DT98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5200" checksum="B651296EA7B0CE58" modified="2014-02-19" version="1">MDSDGLKAVTEAYEQAVFAPHGVPSETADNAVDASDDVADTRSSVSRSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT99</accession>
    <name>V6DT99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="6114" checksum="83497CB3475D272B" modified="2014-02-19" version="1">MTRCIKPNKYIINEILSKWNLYQIGLDRSKEYIIEICSLQGNVQIVVLRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA0</accession>
    <name>V6DXA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01549</name>
        <name evidence="2" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078347.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128167at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14615" checksum="27DD7DC6F0FD28F4" modified="2014-02-19" version="1">MAPYTVDIDVRFRDIDALGHVNNAVYATYIEQARTRYFREVLDIDISQSSNVLASISIDFRRPVELSDDRVTVTVDLAELGRSSVTMAHEVRVGDAVVAEAEATIVSLDPDTGKPTPIPEDHRAAIESYHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA1</accession>
    <name>V6DXA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_06190</name>
        <name evidence="1" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="13494" checksum="CE2EB5412BB814C9" modified="2014-02-19" version="1">MCASEEPPDEDSYADMERFFDAELRAIAAHVLLPVGARATERVLETYTARAWKTEIDMEALHGEELLGAGWLVVPIKDPADWADGDADRLVAALGELRSTDFRRESDLGRFIAGDEPYLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA2</accession>
    <name>V6DXA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Circadian clock protein, KaiC</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_14007</name>
        <name evidence="3" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078325.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55361at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030665">
        <property type="entry name" value="KaiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010624">
        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039117">
        <property type="entry name" value="KaiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KaiC" evidence="2">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="KaiC" evidence="2">
        <location>
            <begin position="243"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="486" mass="53666" checksum="99789CCB453B8A17" modified="2014-02-19" version="1">MAPSLSDRLSTGIPGLDEILSGGLIRERSYMIRGQAGSGKTILSLHFLAAGVERGETVLFINLEEDLSDLKANAEALGFDTDAIEFLDLSPGADVFTEDQSYEVFAPEEVEREPITERIVEGVTAVDPDRVVVDPLTQLRFLMSDDYQFRKQVVGFMRFLKDRDATVLFTVQDTESLPTDDLEFVTDGTIRLDTAGYGKTIAVPKFRGSSTQGGEHAYRVTDAGVEVYPALQPGEHAVEFDFEQISSGVDEVDALLNGGIERGTVSIVSGPTGAGKTTLSTQFMREAAKRGERSVIYLFEESEETFLSRSRAIGVPVDEMIEQGTLQVTEVEALERSPQEFARMVREEVEARDAKIVMVDGIAGYRLTLRGTDGTMLQQIHALGRYLKNMGVTTIFVDETRNITGEFQATMENMSYLADNIIFLRHIEVDGELRKAIGVLKKRTSDFERTIREFRITDRGIEVGEPMSQLSGILSGAPEAVDRDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA3</accession>
    <name>V6DXA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5105" checksum="E7AB02F72BBDE53E" modified="2014-02-19" version="1">MVRDAFGVSSSRKALCAFRTTASVCPPRDWGFGGLRCEAILDKNSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA4</accession>
    <name>V6DXA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK40997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4352" checksum="A30C5AEF1AF41D7E" modified="2014-02-19" version="1">MFLPFRSRPDFVSGIVTRVNYTHTYESCVGVSVIRCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA5</accession>
    <name>V6DXA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06445</name>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077891.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121764at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="7169" checksum="D58EE00F025AB7E5" modified="2014-02-19" version="1">MKIVDGDKAECDRCESVFPLADVSLLEKETNRDYERVLCDECLGIVGVPRGYNLRRDITHLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA6</accession>
    <name>V6DXA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterio-opsin linked product</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_14756</name>
        <name evidence="2" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077497.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89501at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="167" mass="17990" checksum="C3661D7046C4A4D1" modified="2014-02-19" version="1">MNRGPPDESEEPSDDASDPADDPFAASDTILIAADPATVFAFLDDPANHAAITPGLTDVRDVEPLENGGKRLSYTYRMAGMGIDGEIVQTVHDPPERHVFELRGRLTGTIDLRLAPVESGTELTYAATYGLPENALTRVGAPVIRRFNERQLRAALENVAARFGGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA7</accession>
    <name>V6DXA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4330" checksum="EC892AE9BAE37A40" modified="2014-02-19" version="1">MSRRVAATEHSEVDRLGEFKSGRRHSFSVRFKFESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA8</accession>
    <name>V6DXA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prephenate dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_09628</name>
        <name evidence="8" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078357.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000025.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47176at2157"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="183"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK41002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="28880" checksum="F92ACCC2AE62A023" modified="2014-02-19" version="1">MNAVTLGPAGTYSHRAARAVAAEVSFRESVTAIVDAVADGEFERGVVPIENSIEGSVTESLDALAEYDVSVTREVVTPIRHALLAQDDEFEVVASHSQALAQCRNWLETNYPSVGLEAVASTARGVERAREDARVAGIGHPDNAGDDLEILAEDIQDRTSNATRFLVVGPESAKSDAGGKTTLIVYPNANYPGLLLELLEAFADRNLNLSRIESRPSGERLGDYLFHFDVDAGLYEDHTAKAVEDIEAIADKGWVKVLGSYDAEHVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXA9</accession>
    <name>V6DXA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hmuk_1561</name>
        <name evidence="3" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078331.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105930at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="293" mass="32458" checksum="4396F34ECF15623F" modified="2014-02-19" version="1">MTQLGMAIDLERCYGCRACMEACKVENSTPRGAFWMHVFRFEEGEYPNTEQTNMPRPCQHCSEPSCASACPTSARFKREEDGIVLTDYDRCIGCRYCEIGCPYGVNYAQFEHPEDAQYGYGSESNEHNGDDTHGSGTFAEALGDEAPGEGKPPWHDPILDEPTEPRGTQMTGPQPEGVMSKCTMCAHRQDNPERGQQGTTACQETCPVDAIKFGDMEDPESDPNQHLEDKSSSSTFKLLEDRGTEPNVVYIGDEPGDDARTIEDADTFKDPQEAIEIEKNPPESRSTDVEVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB6</accession>
    <name>V6DXB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-1-phosphate guanylyltransferase (GDP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_16239</name>
        <name evidence="2" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="41"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="14491" checksum="116E9F8CACE6A3ED" modified="2014-02-19" version="1">MSGVTESYERVNYTDIEPVSGAMRPLTDSLDSERVGVSIARCEPGWRSKPHDHAAEDHEEIYVLLEGEATVVIDDEPIDLETGDAVWIPPTATRQIRNGDAESAFVLVSGPATDCRSATCPDEPGSWVTDGFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB7</accession>
    <name>V6DXB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hmuk_2763</name>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077532.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101719at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12294" checksum="4CD21F8A838B6C43" modified="2014-02-19" version="1">MTDWERVIQELEEAGYSGFKFDSGDTAVSGLSGEWVSGKIPREGGLKHENQTLWIRILDALSWNGGTVDAAPENAPERIRNIATEHGLDVVIFTVSAEEARIALCDPSKHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB8</accession>
    <name>V6DXB8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C473_12211</name>
        <name evidence="7" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="80608">
        <property type="entry name" value="M.HspAJ67ORF9P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="393" mass="44277" checksum="C5EBE86ED37B2FB7" modified="2014-02-19" version="1">MSVGADGDSASGSDAATDATDAPVVAGFFSGCGGLDLGFERAGFDVALGSDQWEPAAETYRRNFPDVEFVDEDVRELDAAAIRESVERAGYDPGGVDVVIGGPPCQGFSRLNNEQIELDEMEKDRRNTLFEEFLRVVSVLEPRLVLMENVRDLINRQTSDDRYVKDLIVDEFAAHGYKCEYRVLEAEQYGVPQKRRRIFFVGTDRDVPIRFPEPTTPEGSWRTAGEALADASDDLPNMTYANTGEKTLERIRHVPPGGYYRDLPDRLKTKKYRCDCEDTDTCPHEPEIVKRYGTYLRRLHPEEPSLTVSTNVFIHPSEDRYLTPREMARLQTFPDEFAFEGTKTDVLKQIGNAVPVRLGEELARQLLEYFPEVRDAPPADPDVYEQQSLTDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB9</accession>
    <name>V6DXB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7370" checksum="09958D90FFFD816C" modified="2014-02-19" version="1">MSIFGRIVCVQKTFRRITTNVCCRETNQHVRGAPALHRGRATAPRAVGCLRQPLERTELRAPAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC0</accession>
    <name>V6DXC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01977</name>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078341.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110422at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010368">
        <property type="entry name" value="Com_YlbF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023378">
        <property type="entry name" value="YheA/YmcA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06133">
        <property type="entry name" value="Com_YlbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158622">
        <property type="entry name" value="SSF158622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15228" checksum="ECDF476208852A6F" modified="2014-02-19" version="1">MSDAQGSDDATERVADASADETVEENVEAALREFLDALGESETYRRFVAADEALQDDDEAMALLREYRRKQQQMQRGGFDGSVMEELKGLQSELSANETIQRQQAAQADLVELLQRTNDVISEEIGEEFARSTGGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC2</accession>
    <name>V6DXC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonine dehydratase</fullName>
            <ecNumber evidence="2">4.3.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_07481</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="1">
        <location>
            <begin position="22"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="12697" checksum="181DB139B2AFBC26" modified="2014-02-19" version="1">MSPVTVDDVETAAERVADTDIVQRTPVERSRSLSERCGADVRLKMEHLQRTGSFKTRGAYNAISLAVEGTEGGEGSDEPAIERVVAASAGNHAQGVALAASRAGVDATVVHAEVRRPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC3</accession>
    <name>V6DXC3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5611 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07714</name>
        <name evidence="3" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077528.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100538at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040713">
        <property type="entry name" value="DUF5611"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18446">
        <property type="entry name" value="DUF5611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5611" evidence="2">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="14255" checksum="74970F9971F50E05" modified="2014-02-19" version="1">MKQYKMRRGEHLDDRMPDLKGSIEEYFGEVTGTEEYDGHELYVVGDPDNPVFKRIVAGAAEYGSKKDKLAVHFEERPAEEVIADGDADAAADAVDAKNEFLLEATGRDAKSRRDSLKREVEDDAPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC4</accession>
    <name>V6DXC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UPF0753 protein C467_07482</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_07482</name>
        <name evidence="7" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018752">
        <property type="entry name" value="DabA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38344">
        <property type="entry name" value="PTHR38344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10070">
        <property type="entry name" value="MpsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="14989" checksum="E058CF60B9F872D0" modified="2014-02-19" version="1">MDQRAVHFSTVDNAAYGSGSKVTHNPVGNVGVYQGNGGDLMTGLPLQSVRAAADEPYHQPLRLSTVVHAPVDRVTEILADNEAVAGLLDNDWLSLTVVDPTRDHRAFHYESELEWTPLAESERVEPPAETSTTPAAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC5</accession>
    <name>V6DXC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7406" checksum="32798CB4CEF41F2E" modified="2014-02-19" version="1">MAGGVYKRRFSTSGERTATVLSLDIPLLRVCPVKRVSSRATVIDGERSVDTRRGGRARHRGAVRRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC6</accession>
    <name>V6DXC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07615</name>
        <name evidence="3" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077540.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69417at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="22"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="22586" checksum="9CDD06A6F820FD59" modified="2014-02-19" version="1">MSDENPAPVTSERPDAPFHTSGTDHITVWGSNEEDTLAFYRDLLGMPLVLRQPNLDDPSQTHLFFDTGDDRILTVFVSDERASARGQRVNTGAVHHLCFSVEPDEYEEIMASLEEAGKGYNVFDRGIFHSIYTQDNNGLVIELSADKYEIPDGRKGEVLATAQRLREEDGADFAQDRHMEGALEELGIPVNKHDLPDADAGVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC7</accession>
    <name>V6DXC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07699</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077531.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="53231at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PTHR36844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="336" mass="35610" checksum="E8688DD4C5551151" modified="2014-02-19" version="1">MPADEDPIASRADDDRDLYDVATWEERTSLDGLSVALYWLLTRSAKAGIVLVALVGLLAILGSFGIGLLFDPAIAVLLGLSVIPAFGLAAYVYVSDVTTGEPLSLLVATFFLSILTATFAAVLNGRLQPFFRPLGFPGLVLFFFLIVGPVEESVKLLAVRLYAYTDARFDAVIDGAVYGAIAGLGFVVIENLVYIAQNVDLGELTVGIAALGAGDGIAALRALAGPGHVIYSAFAGYYLGLAKFNPGNRGPIVVKGLVLAAAIHGLYNTLVGPVTGIASGLFGVPQVLALFGFVLVFQGAFGYVLLRKIRRYRDAYLDTRDAVDPDVEPELDEFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXC9</accession>
    <name>V6DXC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7578" checksum="AB7F6350FAE37BBE" modified="2014-02-19" version="1">MDRWQYSRSLRTGWKANGQLETAEIGRKGNSKVSSFGGSISRLRGSRGRPQRWSDSYETAAAFLSPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD0</accession>
    <name>V6DXD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C807_03618</name>
        <name evidence="1" type="ORF">BN903_20</name>
        <name evidence="2" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6244" checksum="646731241F590270" modified="2014-02-19" version="1">MGPVDDRKATLGITESSLARAHIDRVACYLDVGSLHPARAEAGKGEVVRLLKEVVSWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD1</accession>
    <name>V6DXD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4942" checksum="B966813C3510B7E8" modified="2014-02-19" version="1">MEPLSSTGVTFPSMISVQPRLIAIDIRNYVSLTSRKSKYIVRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD2</accession>
    <name>V6DXD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK40994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5037" checksum="7E8BFBDBE6226297" modified="2014-02-19" version="1">MLAQGYRLLGPGSLPVGLWGLALVALGVAAASAGLSYLAEARLRAKRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD3</accession>
    <name>V6DXD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9542" checksum="FC5CF6A792F9157B" modified="2014-02-19" version="1">MLVALRNSRHISVVYPIFPRSRLRAPQRSRELGRDPNAVAPVSVRKPQPVPGIIYKCCAAQLSFSRYIYYTLCAGVSWRQNHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD4</accession>
    <name>V6DXD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
            <ecNumber evidence="3">3.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C469_15323</name>
        <name evidence="3" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008008138.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="GeneID" id="55719584"/>
    <dbReference type="OrthoDB" id="89031at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12931" checksum="3DE3F4D1810299D2" modified="2014-02-19" version="1">MATRVLIADDSEFMRNLLREILEGEFEIVGEAENGVEAVNMYEEHGPDLVMMDIVMPIRDGIEATTEILEENPEATVIMCTSVGQEEKMKAAIKAGAEGYITKPFQKPNVLDAIGSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD5</accession>
    <name>V6DXD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_04366</name>
        <name evidence="1" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK40999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078364.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000025.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100794at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="12634" checksum="32F5224F1CB95122" modified="2014-02-19" version="1">MNHVPNEALAAVDAFGEGHLRGDPPAVRERLRSDLRVRITANADGRTARCWFETEHTRAPPTLRNRGSFLATYVDGVDERLREWGIDPPETYEYRETVEGTHRYEGTLSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD6</accession>
    <name>V6DXD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4867" checksum="B2CCE56E33726E95" modified="2014-02-19" version="1">MSTADILIRANPSHIYSLGYGRSDNRHRNARRRRAARGSTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD7</accession>
    <name>V6DXD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_12021</name>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9490" checksum="7DAFC33CD1A0F126" modified="2014-02-19" version="1">MVEALSALSDTPVASLVSRDSFSLYRSAGPLPYALWLIETPEGDHAGITFRQTGDATGMVVNDSPAAVEWADAELTSRREAATPIDRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD8</accession>
    <name>V6DXD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06245</name>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="256" mass="28454" checksum="B99BEB5DF15A9AA2" modified="2014-02-19" version="1">MTEHGTAQPSDELRKAAMRRPHLREHLREFKQITGEFPQFIEEPKDEYESDRPNVIYPVGGPIYSHIYGDLGQDTKYYAIEPEVSGPQVEVLNEVKNRLLTASGQHTAPDNEAEYDDLIEELLEEVTHVDDTSSGWRKGLSKLKNFGKLSVTEETYENIRYRLNRDIVGLVPSSRSCATRPTRTSTSSAPRSATSTTAPTACWRRPSTSGRHRSSTTGCGTWASGWATPSPTPTRSSTPRSPTGRVSTLSTPTTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXD9</accession>
    <name>V6DXD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cysS</name>
        <name evidence="9" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="8">
        <location>
            <begin position="143"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK41004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="267" mass="29358" checksum="4B5CE763169B2409" modified="2014-02-19" version="1">MSTTHLGDTLDIHMGGRDLVFPHHENEIAQSEAATGETFARHWLHVGLLEMDGEKMSSSIGNFWTVPDALEELGVNVVRTFYAGAAYRSEQALTEETVAEAEERWERLSRTYDRAVDALDSTDAGAKAEDAALRNAVETARDEFAAAMNDDLNLREATAALLDLTDAVNRHVDGIEDGSSNAYDYRALREAAEAFEELGGDVLGLQFESPSDGDVDLAGELVELILDVRETEREAGNYERADELRDALREVGVEIEDGPDGATYRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXE0</accession>
    <name>V6DXE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06264</name>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077592.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76189at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="29779" checksum="E39AF9B50BAF5CFB" modified="2014-02-19" version="1">MAVFVALFLAVAGVAGALTATADSPEIAFESPEVDAANGDTVQIGGESYTVGISESEEGGGGHGGAATTVVTGTLEREFTAETSETWTNGSTVSIDDREWRVEITGESPSEFTLVEVLDRQAILEADDSADNQTVTSDAGEEFVLVTDESGETTSVPADEYFPEPEERSYASGDTLQYNGNTVTVDDVTADGAVVVWETTQTETIEIEQHSTVTVGDTEYVAHFPDASTLQMTTDIEAYESQASEIEQFNQYNSGLSRVLILSILSSIMLAGMAFIPSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF2</accession>
    <name>V6DXF2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7438" checksum="E4714219A56B24B0" modified="2014-02-19" version="1">MRTDNLQSKQGGLRPAEPERLMPGPRTLRLPRPPPRTLRPRTLRPPTIRPPTAPSTPTCATSKSETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF3</accession>
    <name>V6DXF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphonate ABC transporter, permease protein PhnE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnE</name>
        <name evidence="6" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077924.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="88"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="29839" checksum="0328EA82145493D5" modified="2014-02-19" version="1">MATESPTSTDSLDAAERRTWRRPTAFRNRSAKWAVYGAVLALVVWSVASLRITPGRFISGLGYGYELIDSMLPPETGSENIARLVDRMIETIAMAMIATVSGIAISLPVALGAAGNLSPRPTYYLSRGIISVSRAIDGLIVAIIAVIALGFGPLAGIFAISFKTVGFFSKLFAEDLEDIDMGGVEAIEATGASRFQRLVYGVVPQVVPRFAGLAVYRWDINIRSSTIVGIVGAGGLGVLLQRSYSRYEYDYVAAILIAIIAVVLVAEFVSAVVRRRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF4</accession>
    <name>V6DXF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_06367</name>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077546.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122403at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8893" checksum="5FB0132E8FA83929" modified="2014-02-19" version="1">MRVEFDRDTCVGMFQCVAEWDAFEKNLNDGKADLADSTEAEPDLFVVEVPDGEELDAKFAARSCPVDAIEVYDDDGEQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF5</accession>
    <name>V6DXF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydroxymethylglutaryl-CoA synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_09637</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG_CoA_synt_C" evidence="1">
        <location>
            <begin position="11"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="17471" checksum="0CC33B837E94BFB2" modified="2014-02-19" version="1">MDELKTTEQYQTWYDTAVEPTLELSREVGNWYTSSVHIARVSALRDALTRDREFVGETLLVASYGSGAQAEIHAETIREGWRAEIGGLDIDDQLDARYDLTWDEYEDVHDVHEYDMDVEREIEEFTQPDGEFVFTGWGRMNERKYEYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF6</accession>
    <name>V6DXF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.176</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_11924</name>
        <name evidence="3" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033814">
        <property type="term" value="F:propanoyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050632">
        <property type="term" value="F:propionyl-CoA C2-trimethyltridecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="2">
        <location>
            <begin position="136"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="271" mass="27998" checksum="AB886FD95FA07B56" modified="2014-02-19" version="1">MSAGDTRDVTEAISRLVHRREYAQGITLPSFGGLAAGAYLDRHDAPREALAAVAAKNHANAVDNPVAQFRKPIDVADALDSPVVAAPLRLYDCCPMSDGAAAVVLTREGTAGTGGSSAPRVAGIASATGTHAVAERSDPLSIDSVSTAGERVFDRAGIGPDDVDVACIHDAFTVLELIELEELGFYETGTAWEATLDGETALDGDIPVNPGGGLKARGHPLGATGLSQIVELVWQLRGDLPETRRVDGAETGFAINVAGFGNNSVCTVLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF7</accession>
    <name>V6DXF7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_08669</name>
        <name evidence="6" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078383.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79669at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="8"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="411" mass="42555" checksum="6405FA06DA3BA9E1" modified="2014-02-19" version="1">MALLDVGIMFAAVAVAGALANRLGQSVIPAYILVGMLLGEFVLGRVVLPVVGTVYVPETEFIALGAELGIVFLLFFLGLEFNLDRLLARRRPIGVAGTIDLANFGAGFVLGWLVFGAFLPAFLVAGIVYISSSAVITKSLIDLGWIANDEAEPMLGTLVYEDLFIAVYLSVASALVLGGGDVAAAATDIGIAIGFIVGLLALAQFGTPAFDRLVETDNKEFVALRSIATVVLVAGAALELGVSEAVAAFFVGMAFSSTGYAHEIETLLEPVRDTFAAVFFFWIGLTTNPALFPEVAALVALAVVVTTPTKLVTGYLGGRAFDLNVRRSTRVGLGMTTRGEFSLIIATIAVTGANAGAFDPALAGTINAFAVGYVLVMAVLGTTLMGYSAPFESIATSWLDSADGGDGELSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF8</accession>
    <name>V6DXF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_11553</name>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077933.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130651at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9128" checksum="876B24A6AE960A61" modified="2014-02-19" version="1">MPPSEEPNEQRVREIVREEIAERSRTLLGTVVWTLLSVLAGLVGLQSLQFALYATSIAATAGFVLAGVVVTGASLYLLYLLHWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXF9</accession>
    <name>V6DXF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07525</name>
        <name evidence="2" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077550.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92975at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="226" mass="24245" checksum="E120F832D7791E8D" modified="2014-02-19" version="1">MSPDYGETWVYESLVGGIPGLGISRTLAVALQFVIFEAGVVGLGWYYGTWNAVAAGTVAVVVAAVGSVEMHRLGAKNRLLGTPPEHKRLLFGSSIEIVLGVLAFIALITYLFAWDGAAGPTLIDRLFGPNPPLPVVYLTLLVLWDLTYRIGTSWWSAVVALWRAVHVDLSPEERATVRRLDAENIGFSLVQLALVPFLLTEPVLLGAVVGHVIAVAIVCSAAIWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0P2</accession>
    <name>V6E0P2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin-guanine dinucleotide biosynthesis protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mobB</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000042">
        <property type="protein sequence ID" value="CDK41145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078486.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000042.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93634at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004435">
        <property type="entry name" value="MobB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03205">
        <property type="entry name" value="MobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00176">
        <property type="entry name" value="mobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MobB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="16348" checksum="B062329080178C22" modified="2014-02-19" version="1">MKVLCVAGPSDSGKTTVVAALAERLRECGTVATVKHLTHEPDVDTEGKDTARHRAGGAVHTVGLTDEGTWFATGRDRTLGDVLDEFARTYDYAILEGFSGSDVPKVALGDRTVAPPVVAEAVTADDLDLNDVVRVIDRLPSYDPERSPDRGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0P5</accession>
    <name>V6E0P5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_00686</name>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000049">
        <property type="protein sequence ID" value="CDK41168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6730" checksum="05393ACCFCEEA0BB" modified="2014-02-19" version="1">MSNHPRPTSLGESLAGAKIGTLLLSHLYPHTGGREREMEQQVREAGFDGEVRAAEDGLRVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0P8</accession>
    <name>V6E0P8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12360</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000043">
        <property type="protein sequence ID" value="CDK41150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSDH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="159" mass="17251" checksum="A5DE35AFD6421060" modified="2014-02-19" version="1">MRPETGAIWQCEHGEEDGDEINVVERGGNYGWPIATEACRYGTDDPLAPPHDDRDDVTGPIHYWRCGSEGFPPSGAVFYDGDAFPEWRGDLFAGTLASQYLGRFTVEGAGAEGASVTERGPLLDDQEWRMRAVAVEPATGHLYVVVDAGDAPIARIVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0Q9</accession>
    <name>V6E0Q9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarate reductase/succinate dehydrogenase flavodomain protein</fullName>
            <ecNumber evidence="4">1.3.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C468_05583</name>
        <name evidence="4" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.1" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000045">
        <property type="protein sequence ID" value="CDK41155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078496.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000045.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14218at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="33"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="482" mass="50992" checksum="531DAEB313880889" modified="2014-02-19" version="1">MGSRDAEPQRRTLDDASAEVVSADEVEFDVETDVLVAGAGGCGLTATLAACEDEGLTVTLLEKSDEVGGNAALSTGMIPAAGTRFQREAGIEEQPADMARDILEKNGHEADAELVQHLCEQSVELVHWLVDDWDISLHLVDDFKYPKHSEYRMHAPPGRNGEHLVAEMRDRIEARENAELLTNTPVTKLVAKDGAVEGVVAGAVREEAIRADRVILATDGFAGNREMVRAHCEDDIADALYYGSDGNTGDGIRWGAELGGALASMDAFQGHATVVSGTGALSTYAVVMNGGVLVNADGERFGNESKGYSQFAIDVVRQEGGVAYEIFDERIFERLKGEFDDFDRAVDLGSYTSADTVEELAAELGCDPEASREAVESYNAAVEAGEPDEVGREDGRNVLTAPFYGTEVTGSLFHTQGGLVVDEHARVLREDGSTVDGLYAGGGTATGISGHGADGYLSGNGLTTAMGFGRLAGLHAARALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0R2</accession>
    <name>V6E0R2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase subunit Rpo11</fullName>
            <ecNumber evidence="4">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">DNA-directed RNA polymerase subunit L</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpoL</name>
        <name evidence="4" type="synonym">rpo11</name>
        <name evidence="6" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000047">
        <property type="protein sequence ID" value="CDK41160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078500.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000047.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129321at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_L_2" evidence="5">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9901" checksum="9064A9921AFF9737" modified="2014-02-19" version="1">MELRVIEKTDTELNIEIAGEDHTFMNVLKGALLESEDVAAATYDVNPEQSGGQTEPVLTVKSEEGDPLDVLADAAESITERTDALRDAVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0R6</accession>
    <name>V6E0R6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Naphthoate synthase</fullName>
            <ecNumber evidence="2">4.1.3.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13897</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000048">
        <property type="protein sequence ID" value="CDK41165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="10195" checksum="D2A0D72B87EBAFE6" modified="2014-02-19" version="1">MGMVNEVIPHEELEEVALEWADEMTRKSPTAMRMLKYAFNMADDGMVGQQVFAGEATRLAYMTDEAAEGRDAFLEGREPEFREYPWHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0S2</accession>
    <name>V6E0S2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Archaemetzincin</fullName>
            <ecNumber evidence="1">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">amzA</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable zinc metalloprotease whose natural substrate is unknown.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000050">
        <property type="protein sequence ID" value="CDK41170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11375">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01842">
        <property type="entry name" value="Archaemetzincin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012962">
        <property type="entry name" value="Pept_M54_archaemetzincn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012091">
        <property type="entry name" value="Pept_M54_archaemetzncn_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15910">
        <property type="entry name" value="PTHR15910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07998">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005785">
        <property type="entry name" value="Zn-prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="182" mass="19934" checksum="F3CD91AA81DD8DA0" modified="2014-02-19" version="1">MIAAVKSGSMLVDIVPVGDVTPQVKREASGALRSVYDCDVTVHDDQPIPDSAYDADRTQYRAEDLIETVTRVGGGEKNIGITPEDLYYRRRNYVFGLAYLNGSGSVISTHRLRTSSDGGVSTKPAVDVFGDRVRKEVVHEIGHTLGLEHCDNSKCVMSFSPTVREVDVKEENLCGTCSRLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNH7</accession>
    <name>V6DNH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6069" checksum="E77D75B8F48F3533" modified="2014-02-19" version="1">MYGILLESLTKRMTRSPIATSKRRLSAVESFSLTSDLDPSCTESLSRYQLNSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNJ2</accession>
    <name>V6DNJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde Dehydrogenase</fullName>
            <ecNumber evidence="5">1.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_14772</name>
        <name evidence="5" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="4"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK37802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="382" mass="39308" checksum="FC6BCF96A057CD7B" modified="2014-02-19" version="1">MSAARGTPSSAARRFRLAAGEARDLARTHGEYREGATPGHEGWTAIVKPEPIGTVLCIAPYNYPLQTTALQVAPALAAGNAVVVKPSSKTPVTAALLTDVIVSAADLPDGAVNFVPGRSQEIGDTLAGDDRVDTVAMTGSSAAGKHVASASGITNLVMELGGNAPALVFPDADISDAAGACATGSFKLSGQRCSAISRVVAHESVHDDLVDRMGSTMDSWVAGDLFDEATNFGPLIDESHAEEVAGLVDDAVEDGADLVAGGGRDGAFHEPTLLANVPQDAEIMHQEQFGPVAAVTTFETEEEAIELANGGELALDASVFTTDHNRAMRVAERVDAGSVRLNGAPSHGLGDVPFGGNDASGINREGVHAAIEQMIRKKSIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNJ5</accession>
    <name>V6DNJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nmlp_3075</name>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="7469" checksum="DBBC9EBDE5C61362" modified="2014-02-19" version="1">MNSNVGAVDRTLRTVVGAVAGGVSVAILTGTVSLPTVLSPVLGIIAIMMLSTASIATCPAYSLFGVDSCSGNSSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNJ8</accession>
    <name>V6DNJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4364" checksum="B455C5831CCC3759" modified="2014-02-19" version="1">MQNTPTCPAFDNEDSTYNCGPDNGADRNADGVDRDEKSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNK1</accession>
    <name>V6DNK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4469" checksum="C1399AB96CA469F5" modified="2014-02-19" version="1">MSLNGLNQNHREPDQVRMLRGPRQKNAALLVAEKRLDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNK2</accession>
    <name>V6DNK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_08051</name>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075777.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62124at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="239" mass="25355" checksum="24AA68B5BE51A5C0" modified="2014-02-19" version="1">MSRTAVIAGVGPGLGESLARRFAAEGCQVALFARSTDYIEELATDLPDSGEGLAVTTDLTDVEQIEEGFDAVRDAFGPIDVLVNHASAASWTGLIDTTVEEFEEAWAVNGRGAFVCSQEAVGDMLEADGGTVIFTGATSAVRSLGGAIGFTAAKFAARGMAMDIAQEYGPEGVHVAHVVIDGQIDSEAARERLPDRDGETFLDPDEIAETYWHLVEQDNVSTQPFEVHITNGPQNSEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNK6</accession>
    <name>V6DNK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7724" checksum="18FB9E99565FB840" modified="2014-02-19" version="1">MVVTALVIIDLFFADQSGLEEPLDSAIRRGSLAVGRFSNLVYCKWLLTLNEYLEAYPVQRFVTVETLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNK7</accession>
    <name>V6DNK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C470_13753</name>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114750at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="12722" checksum="6140B29F15014CFF" modified="2014-02-19" version="1">MEHCFACDTDYGYLGTTPHEGSCPACGSSTVTPAGELSVVDTTTWESATGLSTIHVTATDRRARRFEFVVAARRGRGELVCLAIDGTEVPTDTVWSVPSAVATTVTAHGIRLSDSTPSQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP00</accession>
    <name>V6DP00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FeS assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sufB</name>
        <name evidence="4" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="3">
        <location>
            <begin position="138"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK37891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="478" mass="53442" checksum="486D36B396C8D2E3" modified="2014-02-19" version="1">MSSKQDDLKETNTEARFEFKKEEKSAFQTEKGLTEETVRVISEDKGEPEWMLERRLRALEQFQQMPMPTDWPGQPDLSEVDVDEIIPYIRPDVDVRAGVDDWTELPDEIQDTFDKLGIPEAEKNALSGVGAQYESEVVYQNIQERWEEKGVIFCNMDEAVQEHEELVREHFMTKCVPPSDNKFAALHGAIWSGGSFVYIPENTTVDMPVQAYFRMNSEGMGQFEHTLIIAEEGSEVHYIEGCSAPKYSKFNLHCGGVEVFVDEDAHVQYSTVQNWSKNTYNLNTKRAIAEKGGRMEWISGSMGSKATMLYPSTILKGRGASDNHITIAMAGEGQDIDTGAKVYHNAPNTKSTVESKSIAKDGGRTNYRGLVHIADGAENSSTAVECDALMFDNESTSDTMPYMEINESKVDVAHEATVGKIGDEDIFYLQSRGLDDDDAKQMIVSGLHRADHGGAADRVRRRAEPARRARDGGLPRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP01</accession>
    <name>V6DP01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5373" checksum="6B39C7454514CF57" modified="2014-02-19" version="1">MVIPATDPYYQLKAKKLFFLVGRFICIHAVRPNNDVLGFYFHDARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP02</accession>
    <name>V6DP02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_11918</name>
        <name evidence="2" type="ORF">BN903_169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="14268" checksum="FCC1DBCA64FE42FE" modified="2014-02-19" version="1">MELAIAGGAVAVAGAMIPDWDQRVPFVRHRGPTHTVWFALIVGTVLGVPGALVGSSVGVVGAIALGGFGFVVGTIIVIGHLLADVLTPMGIRPFEPLRDDTYTLDVAKAANPLANYALLALGAVTSVIAFLAGSVVAGALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP06</accession>
    <name>V6DP06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_01849</name>
        <name evidence="1" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="123" mass="13657" checksum="BA8751A353C9A998" modified="2014-02-19" version="1">MTSNVTRHQRDNLTTTPYSVRNHDSQLVFFDGQLPDEVARKKGIRQQTLAALEHVSNVAAEAGVHVRNLMRTTVYLTEIDQSEAVTQAYDEFFDGQRPSRTVVGAEELPSDAAVQIEAIGVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP07</accession>
    <name>V6DP07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_17263</name>
        <name evidence="3" type="ORF">BN903_174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="14822" checksum="3E341D4DED3CE27A" modified="2014-02-19" version="1">MLVVKRASDGGWELPGGRLDRGEDAVDGLERELREETSLEPEIVAPVHTLAWVNDDGNGRFAAYYYSRAPRRQVTLSAEHDDADWRPIPVVGSRLNDPQTAAIDAAVTRHRRSLETDATGRATGQRERSDGSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DP24</accession>
    <name>V6DP24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C494_15308</name>
        <name evidence="1" type="ORF">BN903_182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075875.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104444at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020994">
        <property type="entry name" value="Uncharacterised_Ca-bd_CcbP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11535">
        <property type="entry name" value="Calci_bind_CcbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="13839" checksum="A111CEE348539B31" modified="2014-02-19" version="1">MTERDEEREERIKMRIIVDAYTQDEQAMGWHIYLEETMDFTFEAHCMEEQEISPLEQGETVRVVDKPSSEPSLRQQFVTVEWMGRELSVPLEQLEPIDASSDTEQAISDWHYWLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR0</accession>
    <name>V6DRR0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_15067</name>
        <name evidence="4" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075822.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117039at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023368">
        <property type="entry name" value="UPF0066_cons_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00104">
        <property type="entry name" value="tRNA_TsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01318">
        <property type="entry name" value="TSAA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="8"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK37883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="17600" checksum="ED98960833B3AEEB" modified="2014-02-19" version="1">MPTDTFSYESIGVIRTPFESPEGMPIQPVGADSVTGTVELDPSFADGLADLDGFSHCILLYHFHASGDDAPLSVEPFLDDERRGVFSTRAPQRPNPIGLSVVSVKSVEGRKLTVGGIDVVDGTPLLDIKPYVPEFDVPSETETGWMDASASTIRSEQADKRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR2</accession>
    <name>V6DRR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12151" checksum="9AF6FB52D63A96F2" modified="2014-02-19" version="1">MSTPLAEAVPSTPSSSFSRLEQPASPLIPPTAAPAFMKSRRRTPGSSESNPSVEPVVWLPDSASVDRCVSFDIGESASGDSLATGGRCGLRYKSRQAAPCAVGSARTRSAIGIGVSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR3</accession>
    <name>V6DRR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S14.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C463_00105</name>
        <name evidence="4" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075826.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122051at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK37888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="7011" checksum="A77558FD4A78C0F4" modified="2014-02-19" version="1">MTRDTSNEDGSIERSTEASNDDRHVCRVTGREQGLVGKYDIWLCRQSFRELAPAIGFEKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR4</accession>
    <name>V6DRR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_11274</name>
        <name evidence="3" type="ORF">BN903_178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021793">
        <property type="entry name" value="Oprl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11839">
        <property type="entry name" value="Alanine_zipper"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="30261" checksum="EFC719B6329B7D98" modified="2014-02-19" version="1">MRIARLQSSVADIEAYADALAEFIDGEGTAREILDGIDERVDAVESEVSALDVRLDDADDEREAIESDVARVDSAVDSASDAVGAVEERVDGVESDVEAVEGDVQGVEEDVRDVEDDVRAVEEQVGSVDEAVESVREAVSTVETDVDDLGADVDRVEGEAEAVAESVDDLGDDVETLYEEVDKAAERAENAEEAAEDAAERADTTADRVDDVESDLGRFDEEFDDLWNDLAEVDTRLTDVEDRIGEDLDDVAAELDEINEHLDELDEFRTRLNEAFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR6</accession>
    <name>V6DRR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04113</name>
        <name evidence="2" type="ORF">BN903_191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076645.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102297at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043867">
        <property type="entry name" value="DUF5827"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19145">
        <property type="entry name" value="DUF5827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="11326" checksum="600A024F149B5B4C" modified="2014-02-19" version="1">MPEPKSAFDATYPCDFYEPAELFEPDQMYTIPEIGRLLQGLEPDAEVDPDTEAVLVDWAVPWVMVHAEDMVVAEPLSEDGPGYYGLVTDDEPETETDADESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR7</accession>
    <name>V6DRR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11459</name>
        <name evidence="1" type="ORF">BN903_150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076605.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108743at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="22353" checksum="961FA5DE03CAEDE4" modified="2014-02-19" version="1">MFVEHLPDDRGQAHTLEAFTAALLLVAGLIFATQATAVTPLSASTSNQHVENQAAIAAQDVLTTTGESGNLTAALLYYEDGEFVDSGDETSYSGVPPASHPLHDPLTEAFGDRQIAFDIEVFYPEDGGNRTGDTTMVDMGSPSDNAATASTRVALYGDDRLFNASVDDPGDATYSGPRLAEESQHDYLAPSAGGSDTLYTVVEVRITAWQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR8</accession>
    <name>V6DRR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14744</name>
        <name evidence="2" type="ORF">BN903_182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10054" checksum="05559EA54A92146B" modified="2014-02-19" version="1">MELSDIRSELVAMPSETDEQLESVRRLLWVVVFLLGIGVAALGDVAAAVRGYGTLISTVARATGILTVIAVLALLYWRLFRIEPEPEPEEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRR9</accession>
    <name>V6DRR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C470_13753</name>
        <name evidence="1" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="12601" checksum="5103193ECE2041F3" modified="2014-02-19" version="1">MEHCFACDTDYGYLGTTPHEGSCPACGSSTVTPAGELSVVDTTAWESANSLSTIHVTAVDARARRFEFVVAARRGRGELVCLAIDGTEVPTDTVWSVPAAVATRVTAHGIRIGDSTSAQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS1</accession>
    <name>V6DRS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_01396</name>
        <name evidence="1" type="ORF">BN903_155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076611.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95735at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="146" mass="15795" checksum="CF0F32CD4EE2BA37" modified="2014-02-19" version="1">MNTVTLSRTVDAPPETVRDAMRDVEPFVRSSGFDEVAVDGETVRVANDVGIASIELTLELVDDPDADLAYEQREGIFESMRTAYVVTPTADGSGVTATTAFALDVALVGDFLDATVIERQRRTELSAQFDWLEDRCGSDARGEGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS2</accession>
    <name>V6DRS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA protection protein DPS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_01839</name>
        <name evidence="3" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075831.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61631at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01052">
        <property type="entry name" value="DPSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033921">
        <property type="entry name" value="DPSL_diiron-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="2">
        <location>
            <begin position="39"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="219" mass="24766" checksum="BEBF834E568F1E87" modified="2014-02-19" version="1">MSEEKEHGSGAVEPGDTSKRVGAEVIRERGVDPEELREKLIDAIGAEFTTYYYYTNLRMHLAGEEDYKEITEDARLEDRAHFELVVPRVYELEGSLPNDIRDFADRASCPDAGVPTPMDDGGNFDTSDLEVADILEVLLEAERCAIRTWSEICDMTRGADPRTYDMAQRILNEEIDHEAWFIELLSKERDDEINPAGHFARGEPGDAPYTKNTQFNDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS3</accession>
    <name>V6DRS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4152" checksum="FCAF4AE4492C39C2" modified="2014-02-19" version="1">MGLEAAQGPETVVRALYVSIELPSRRLERRLLTNNTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS4</accession>
    <name>V6DRS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metabolite transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_02974</name>
        <name evidence="6" type="ORF">BN903_188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076641.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38526at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="5">
        <location>
            <begin position="21"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="465" mass="48389" checksum="64F4144B7DA4A939" modified="2014-02-19" version="1">MSTADMGAVIRGEGGRFVYVVSALAALNGLLFGFDTGIISGAILFIDTTFELSPLVEGIVVSGAMVGAAAGAAVGGQISDRVGRKRFILLSAGVFFLGSFLMAVAPTVEVLVAGRMVDGIAIGFASIVGPLYISEIAPPSVRGGLTSLNQLMVTVGILSSYFVNYAFSGSGSWRIMLGAGMVPAVVLAIGMVRMPESPRWLYEQGRTDEARAVLRRTRDGDIGSELSEIEATVEAQSGNGVRDLLSPWMRPALIVGLGLAVFQQITGINAVMYYAPTILESTAFGSSQSILASVAIGTVNVVMTVVAILLVDRVGRRPLLLVGTGGMIGSLAVAGLVFQFADPTGGMGWLATLTLVSFVAFFAIGLGPVFWLLISEIYPLAVRGSAMGLVTVANWLANLVVALSFPVLLDGIGTPMTFWLFGACSVVALLFTYRTVPETNGRTLEAIEADLRKGTGAVGGARGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS6</accession>
    <name>V6DRS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease P protein component 2</fullName>
            <ecNumber evidence="2">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rnp2</name>
        <name evidence="2" type="ORF">BN903_160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902555">
        <property type="term" value="C:endoribonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="SSF160350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7745" checksum="BC10585AE483D95E" modified="2014-02-19" version="1">MSEVDGEPVGILVRGISGTVRACEERYMGRATPNSTQRDVAFGSAERPAVVRGDACDLRAESGRVGATTFDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS7</accession>
    <name>V6DRS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C486_13722</name>
        <name evidence="1" type="ORF">BN903_201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115435at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="9751" checksum="99E8765A03C8B3BE" modified="2014-02-19" version="1">MTRPSPAAALNGVQCGNICSKCNQGIRTGDKAVIYATYYDADGWVVRRVWCDDCGSTTIGLTTDGADEVVVSAVYWSGRLVGVTTVDRSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRS9</accession>
    <name>V6DRS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11314</name>
        <name evidence="2" type="ORF">BN903_165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6528" checksum="F5B0B566F409D5B4" modified="2014-02-19" version="1">MFESVAASTDFAALGDASLTAHYDPSAVLVLGEYDLTGAATLLAATGVLVVLAVVRFRRADLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS12</accession>
    <name>V6DS12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5537" checksum="F785334BAFB0BF75" modified="2014-02-19" version="1">MTVVAIGDRFDDAERSENHPTTPLSPVKLASELPDMKSGIREWRFDLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS13</accession>
    <name>V6DS13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3806" checksum="7DCE9BBA995A8337" modified="2014-02-19" version="1">MSRDRRCGRGGTGPDLAGCGASPNPPGGGLPPGKRFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS33</accession>
    <name>V6DS33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5055" checksum="894C6D0FF8D5EF21" modified="2014-02-19" version="1">MAPSLINARGINDRLSLGYDVRSQTRVTSQKSCPEHMTNFGEIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS37</accession>
    <name>V6DS37_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="13736" checksum="265AE2F582A523D8" modified="2014-02-19" version="1">MTYAVYFYVLITVGSLLSIAYSLRGGQYLSSLHAIGLLLVIFAVGFSVLRGDYLQTDVRSRASEDDPGEDGDHDTVGDLPFSAGFWEALYTRYIDRSGFRRVEMGMYAVGVLSLAIVQAAVKFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS38</accession>
    <name>V6DS38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_16032</name>
        <name evidence="1" type="ORF">BN903_301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="169" mass="18637" checksum="82FF26E43079F9BF" modified="2014-02-19" version="1">MVVRETGGVEDYRLVATAVGETTSKQYVRPETGERIVAGLRAAADLADTTTLTAFEVICDTPDMQDTYLGNAERADVYRFARRNAAHLTTDMTEPDDFEGWLESVKTARILDEWIGGATVEDLVERYRIGPGDLDSRVERAEWLLSAAEALGETIGVRVPAVSRARSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS39</accession>
    <name>V6DS39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6424" checksum="A2DBDDB1F6DFC056" modified="2014-02-19" version="1">MRHLAFLFVPALKELTIRGYRLNARQPHRRVESRNAYAHDGRTFGRSQYTTGIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS41</accession>
    <name>V6DS41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase cyclophilin type</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_10960</name>
        <name evidence="3" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="176" mass="19145" checksum="603CEB9FDB36F886" modified="2014-02-19" version="1">MTLQTNHGDIVVELFADRAPKTVENFLGLARHDPAADAEPARDTNTWEDPKTGEVRGDSLYEGIVFHRVIDDFMIQGGDPMENGRGGPGYEFADEFHDDLTHDGPGILSMANSGPNTNGSQFFITLDATPHLDGKHAVFGQVINGMDVVEEIGGVPTGRNDDPREAVEIEKVDIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS42</accession>
    <name>V6DS42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075905.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="181" mass="20587" checksum="419D695FCB6441D7" modified="2014-02-19" version="1">MRRRELLSTSVIVIGGLSGCLNRIPLIGMNPEEVVTEFYESQFALDVETANSHIHRGSRIESITMRDAERMQIHEYSLISVTESDTDPQPEDHFLNETEVDTELEILYEELDQLDGAGEALEEEINHYEDGTNPQVATVSDMAEVEAVIDYNENGRRHRPTRPVQLLKDGNGWKIWTISSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS43</accession>
    <name>V6DS43_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C472_04678</name>
        <name evidence="9" type="ORF">BN903_280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076715.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74803at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="90"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="199" mass="22630" checksum="33BED863AF453B77" modified="2014-02-19" version="1">MSYELDPLPYDYDALEPHISEQVLEWHHDTHHQGYVNGWNSAEETLEANRESHDFSSSGGAIRNVTHNSSGHILHDLFWQNMSPEGGDEPEGALADRIEEDFGSYEAWKGEFEAAASAAGGWALLVYDTFSNQLRNVVVDKHDQGAVWGGHPILALDVWEHSYYHDYGPARGEFVDNFFEVVDWEEPSSRYEQAVELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS44</accession>
    <name>V6DS44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075908.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14604" checksum="AFB1D607BCE8C04F" modified="2014-02-19" version="1">MSLLRDAAVNWGWTIARTHRDDIGVFALKLHTGEEYVYGITKDMPYQGCASFPKKVASRASDNDCPVIVFFGEKPRLGNSYVFDSDTVLCDGYPNMECTSPTRRKLWHDIPLEKGVLLGDYISGRETVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS45</accession>
    <name>V6DS45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00050</name>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076217.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="94047at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="14425" checksum="622C2EED9762855C" modified="2014-02-19" version="1">MPEIELGVPKGVVESLPEEEGTAERDMRRAIAGIQSRLNDALAEADPDEAAEVVADAVERMESQASTYHEFVPELRAWGQSPIYAIAWRNLYLELIGQLYDHEWLADDLDRERNFRLVEDGIRLSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS46</accession>
    <name>V6DS46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6186" checksum="20C35A9A39886D2A" modified="2014-02-19" version="1">MDDGSEGVFAHTFRLSAGYIKIPLRCAGTSVARPDSDPVSAGRGLPGVTRPDCSWGPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS47</accession>
    <name>V6DS47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_03409</name>
        <name evidence="3" type="ORF">BN903_306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076733.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="53008at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043812">
        <property type="entry name" value="DUF5794"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19107">
        <property type="entry name" value="DUF5794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="341" mass="34617" checksum="7E3D20B0E58CCB1F" modified="2014-02-19" version="1">MSTSRHPVALRLEQQVGSATKLLATVMVLPLVDGIFPALVVAGVLGSATGVVETGILIFGGSATAAVILAEMDGSRREMVGSVLLIGAVIIPVAAVEAALAPTLQGLLNLPIFERFAGLVILTIAAKTASSEIGEYLPSPGVIIGLGLVASFDPSGFTLETSTEYVVNGTAAAAVGVAFALSIALLSPHLRGRVDIDRFRFGSAVALGVLALPILLGPFDLMQTDAPVALAVLAVTTLFAYDPNAGALEGTDDDAPDDGNVSDGDDAPDDDDGSSDGDSTDTEDDLAESPPSDPPLDAPPEGSSPVVDDDVAVLANGGEGRETDDDGTDPFTDDDSRAPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSV2</accession>
    <name>V6DSV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5594" checksum="32D3533033B9AB09" modified="2014-02-19" version="1">MAPRSPFGFRWQPTGSGLVIYKTGQNGAVRSLASSPRLNLRVLRFRFQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSV3</accession>
    <name>V6DSV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_09464</name>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008443026.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="GeneID" id="55594228"/>
    <dbReference type="OrthoDB" id="129932at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="10245" checksum="3750E4DDA85193A6" modified="2014-02-19" version="1">MEGTQTEGLDDLPPSAKLVFKVLEYNGPLTQKGIVQESMLSARTVRYALERLEGIGVVDEDVYFADARQNLYKLTEPAQEFTADEGEASCTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSV4</accession>
    <name>V6DSV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter</fullName>
            <ecNumber evidence="9">3.6.3.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C473_05962</name>
        <name evidence="9" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.31" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076997.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="48"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="80"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="395" mass="42537" checksum="BC3B4DD81DC417E5" modified="2014-02-19" version="1">MASTESVGTTRSAESDDAATEGSDDRSVDHRADSASDDANAASADPVLSLSGVTKAFGPETAVDDVSLDVQSGELLTFLGPSGCGKTTTLRTIAGLEEPTEGRISLDGDVVAGDGSFVPPERRDVGIVFQNFALFPHLSVRENIAFGLTDADAPESEARVDELLELVEMTDHGEKTPDQLSGGQKQRVALARSLAPEPEVLLLDEPFSNLDVRLRVEMREEVRRILKAAGVTAISVTHDQEEALSISDRVAVMNDGKIEQVGRPESVFERPESKFVASFLGRASFLEGELRDGKVKTGIGRFDAVTLEGYDTVYDGAPVDVLVRPDDLRATPASPELADGVVTSRQYVGPSFVYRVELDSGEAVHCLHNHVEEFDLDESVTLELTADHPLAWYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSV7</accession>
    <name>V6DSV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase RIL</fullName>
            <ecNumber evidence="9">3.6.3.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C472_09803</name>
        <name evidence="9" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.49" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03236">
        <property type="entry name" value="ABC_RNaseL_inhibitor_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034348">
        <property type="entry name" value="RLI_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="PTHR19248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="50"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="76"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="355"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="577"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="584"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="116"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="388"/>
            <end position="395"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="646" mass="71266" checksum="A8AD7CA721CC7C7E" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSV8</accession>
    <name>V6DSV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_02171</name>
        <name evidence="2" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="310" mass="33091" checksum="7006588E2A90D4AC" modified="2014-02-19" version="1">MITSHIKSAVDRLQAELSPDSGRICVVSSSLLLSGPSPFSRVGGYLMPKRRSMLFGLGALAMGSGAAFSSAAFQNSVSSDADLRVVVEQNLTIGPGSAFDNIGEGGKFTDNPNLFNGQDLDERDSGAFDEDTVPPLAYVDGENEDLDVRMAVPLNDTTTFENILEIDGPVDETVNVGIAYDRFPDDGDRNQYGEDITLAGGSLSPEIARQAYQFTVNDDESQGGTRISPNNNAEGVGTDETVKQAYDRPADVVTVGPGETVSLDLDIDTQYYYEAIRGAADIAPKQFGFQRDTVQLIDGFTVGTMTGDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW0</accession>
    <name>V6DSW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalamin B12-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_09913</name>
        <name evidence="6" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methylamine corrinoid protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076987.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89832at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="15050" checksum="D3895730385A1D63" modified="2014-02-19" version="1">MSAEQQERAVRCLVAKVGLDGHDRGAHVIARAFRDAGFEVVYSGLHRAPDDIVQAAVQEDVDVLGISILSGAHNTLVPKVIEGLKEYDAFDDTLVLVGGIIPDEDETKLKELGVAEVFGPGTPMEETIEFIRNNVPERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW2</accession>
    <name>V6DSW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Natpe_0331</name>
        <name evidence="1" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334932.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130647at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="21103" checksum="9FE7F1351FE91EA8" modified="2014-02-19" version="1">MPNRRNVLIGLGGLVAGGGALIGTGAFSTVEAERTVNVQTADDANAFLGITAARDSASYVTETDGTVQIDLDGTDSDAGGLNENARTRFENLVQLQNNGEQEVTSLTLEVEVTGTTDNAPHEEAFKITTENDYTLNPTSGNPVDLLGSDANNDYYSSGNGTLTSGNTVTFGVEIDLLNNENISEIADDASFTLTIGAETSGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW3</accession>
    <name>V6DSW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C465_09810</name>
        <name evidence="6" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="67"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="248" mass="27135" checksum="3936F384A1AD50AE" modified="2014-02-19" version="1">MMTPRLDVTAVAKEDSVEEAIETCIQADHERVPVYEGNLDNIIGVVTVRDLVRELRYSEGQPSLERVVKPTLHVPESKNADELLAEMQDNRLQMVTVIDEFGTTEGIITLEDMVEEIVGEILEGDEEAPVEFLEENVAVVQGEVNIDEVNEILGIDLPEGEEFETLAGFVFNRAGRLVQEGEEIEFDEIRIRIERVDNTRIMSARVTVLDGAPAAEDSGAPVEAADSTAEGGTVEADGDGTPARNNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW4</accession>
    <name>V6DSW4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Huta_1737</name>
        <name evidence="1" type="ORF">BN903_285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="17415" checksum="431B9FBE830C7E1F" modified="2014-02-19" version="1">MFLCESTNSADIEEKTFQERFGRTGMRRRQCLRAAGACSGILALAGCVETLPGGNAPPDYPGGTLVVENAGDSPVRVSVDTKLEQFDAQLDVEVAGGETVVRREFVTAETGDIVTLEALLGETGERIRFQFLPAGGGEDTPPEVARLTFESGVEASATWTATAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW5</accession>
    <name>V6DSW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, CopG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_06077</name>
        <name evidence="3" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076990.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130007at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="2">
        <location>
            <begin position="3"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="7029" checksum="9893B25526A2498A" modified="2014-02-19" version="1">MERVTLRIPKQQIDEVEQMVETGEFPNRSEAIRSAVREMLNEQDGERDERGRNRNWAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW6</accession>
    <name>V6DSW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10647" checksum="FCEABB5E2F920049" modified="2014-02-19" version="1">MRYVPRLYHLGGAAPTRRIRIAARRTLPAGDARVLSARHRPFVALAYPVATVALLTGTVALAVLSRSVLRTLRRRSGRVQTLTLPGLGTVEYRITTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSW7</accession>
    <name>V6DSW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C468_01240</name>
        <name evidence="4" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334931.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="152"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="223"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="273"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="402"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="609" mass="68043" checksum="292D0E29E5590FB9" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY0</accession>
    <name>V6DSY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na+/Ca2+-exchanging protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_04076</name>
        <name evidence="7" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076986.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43312at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="189"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="350" mass="36270" checksum="20C8AE968579FB4C" modified="2014-02-19" version="1">MTVLQELIGDQSLVVWIVLGAIGFLLTWKGANVIESTTSKISDHFGVSQAVQGGLIVAAATSFPELAIIIISVLVLGDFGVGAGALIGTAVFNILVIPAAVSITSGDTTTTQGIVYRDAIFYMVAVLALFGVIALGVLGTDGRELTRITPQMGVGLLVLYGVYVILLAGGKSGASDLKRTESANLPKQVGLFAAGLVVVLVGVESMVTMTVQISEALDAPSFLVSVTLLSAMSSFPDLLVGVKMGKAGDKRAAVANVFGTNTFNLVAALPIGVILAGGVSIGFLTSVPLLLFLFYTTLAVVVMAATEFEITTEEGYVFLAMYFAFLGWMTTEALGVTTLLTESTLRTIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY1</accession>
    <name>V6DSY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6921" checksum="EEB7972B60B22343" modified="2014-02-19" version="1">MIRLRGRGRLVRVESRRSRAPIRSAWNSKSYVERLFHPVRRLAFRSSRVRSGGRRGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSY8</accession>
    <name>V6DSY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_06682</name>
        <name evidence="1" type="ORF">BN903_315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076399.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68638at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="235" mass="26723" checksum="F21DDD7778BEAD98" modified="2014-02-19" version="1">MSRRSDLDDLYDLLDCLEANVGGKRRLRDCTGYMNWPERGVYFFFTEETRDSTGQLRLTRVGTHAVSSGSGTSLWNRLRTHRGANRGSYEGGGNHRGSVFRKHVGRAMIERDGLHDEYPHWGEGSSADRERRLAELDHEHRVSEYIRDLPFLWVAVDDEPGPQSDRAYIERNAIALASNYRKETIDPQSDSWLGRNSPHEKITDSGLWNVYHVEEACDPAFLDRLAGAVSETTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT70</accession>
    <name>V6DT70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_12141</name>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076508.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87493at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043858">
        <property type="entry name" value="DUF5820"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19137">
        <property type="entry name" value="DUF5820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14429" checksum="C98B3E5F71ED0986" modified="2014-02-19" version="1">MTFESLPEGWRVWNEEPSGRAILVYRPDVFGGGDLPDECLPTVYLTNGARNARPGSGQYATEEWHVVLFLEPEIEAVSETYESREAGEGGAVDVAERFAAGDVDYRAAYQVPREDYFARLDEYVGGNSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT71</accession>
    <name>V6DT71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6738" checksum="79D245DD84C2A872" modified="2014-02-19" version="1">MSISPLLIDASETETPPVPSVHLSEKAASNWSDSRAETPLVPSEYQVSYPRLKSWASALVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT73</accession>
    <name>V6DT73_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Translation initiation factor 5A</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Hypusine-containing protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">eIF-5A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">eif5A</name>
        <name evidence="11" type="synonym">eif5a</name>
        <name evidence="13" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Functions by promoting the formation of the first peptide bond.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076247.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98221at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00085">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022847">
        <property type="entry name" value="Transl_elong_IF5A_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="Transl_elong_IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="PTHR11673"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 11" id="KW-0385">Hypusine</keyword>
    <keyword evidence="6 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eIF-5a" evidence="12">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="Hypusine" evidence="11">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CDK38408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="14211" checksum="3081657CD4CDE3A4" modified="2014-02-19" version="1">MPREQKQVRELQEGSYVMMDDAPCKINHYSTAKPGKHGSAKARVEGKGVFDDKKRSLSQPVDAKVWVPIIERKQGQVVNVSGDEVQVMDLDTYDTFTMRIPEGEDFTSDDNIEYLDYEGQRKILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT74</accession>
    <name>V6DT74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_10535</name>
        <name evidence="2" type="ORF">BN903_188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077060.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="127469at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="16188" checksum="557215FB1E3AD366" modified="2014-02-19" version="1">MRQLVTQLFRTYGVLAVIVAGFTALWALGVIDVAVPIVGYAWFAVAAVGTVVAAGMVTRKPEVVEEDADTERVEEFEESALSGGPLNLYVASLGAWAAVSFGWVLGGMSAAGLEVVGYGWVAIAVYGVVVVVGLARNHSDDIAVAVDPSETLDADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT75</accession>
    <name>V6DT75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6473" checksum="A9E335AF7F65942F" modified="2014-02-19" version="1">MNDLPAAAAPTGSFRGVSDASPTARDDDPTCETLGASPPTRVSKRHRTHSTGRRRSLVWPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT76</accession>
    <name>V6DT76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_00662</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076512.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95805at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="16862" checksum="C3BEA68F07112B9B" modified="2014-02-19" version="1">MREPFDPGFDFDRGTVAAVTATTILLCATVLFVVDRPAWMLPAAIVAGGVATALGGFYDASANNAILGVTLVAVPLYAFVFVYRIGGVPTPGTDPDLLFATAVYSMGDMLGYLPMMAVFAYLSATVTDRLRRRFEPPVGYPDRGEARRITGLEDETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT77</accession>
    <name>V6DT77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_2971</name>
        <name evidence="1" type="ORF">BN903_156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077101.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6342at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="534" mass="58824" checksum="1EB91ECFAA66C3C0" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT78</accession>
    <name>V6DT78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_00450</name>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076251.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116432at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11227" checksum="B894A8314DC24746" modified="2014-02-19" version="1">MLLLQLDATGTDPFLALGVLVLSVVSVVLSVTIAVVLVRGYRQGPAHRGTLWLAVGLIFLITVPELLRVGLPTVTDIGAVGRSILVSACELFGLGTILWVVYGGGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT79</accession>
    <name>V6DT79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4338" checksum="6F351F2CF238A57B" modified="2014-02-19" version="1">MADFGHPTAWRGRTPSKGHYDWPLHHGTTIPANRRALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT80</accession>
    <name>V6DT80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7974" checksum="75C81683C17D36F2" modified="2014-02-19" version="1">MYPFLMDKMAEQFLEPEISKTQQQIQPRKWNNGSSCHPVEDPADEGGYFLHMCDQLAIGSGVVSPISRWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT81</accession>
    <name>V6DT81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation-associated GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_00702</name>
        <name evidence="3" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076515.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51913at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="MMR_HSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="MMR_HSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="2">
        <location>
            <begin position="3"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="400" mass="43492" checksum="5516F868B2C97DB5" modified="2014-02-19" version="1">MSYRIGLVGKPSVGKSTFFNAATMNDVPEGAYPFTTIDPTVGEAYVRVDCAAPEFDETCTPSVGVCREGTRFVPVKLVDVAGLVPGAHEGRGLGNQFLTDLNETDVLIHVVDFSGKTDIEGEATEGHDPREDIDFLEEELDAWYLDVLEKGLEKFETRYHGADAAIEAELADQMSAFGTDKDRMKRTILAQDLELDPETWDETDRIELAREIRKRTKPMVIAANKMDTPEAQANWETITTDPDYDHLSFVPASAHAEKALKNADDAGVVDYTPGASDFEVVGDVSGEQEAGLDRIGEFVSEYEGTGVQGALEAAVFDVLGCIAVFPGSANGSKDEKGVFRDCFILPEGSTTEDFAYHIHSDIGEGLLHGTDCRSGRQVGTDRELSHRDVIELVSTNQAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT82</accession>
    <name>V6DT82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase beta domain protein region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_11905</name>
        <name evidence="1" type="ORF">BN903_161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4824" checksum="20D0710C19B5F8E1" modified="2014-02-19" version="1">MRELVSLTGANKGTISKAVKLLSELDLVETAPDGRTQQIQINRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT83</accession>
    <name>V6DT83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydroxyacetone kinase, L subunit</fullName>
            <ecNumber evidence="3">2.7.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_12115</name>
        <name evidence="3" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.29" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaL" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="11749" checksum="F5E3DB5AE2E12C56" modified="2014-02-19" version="1">MDALTPAVHTFKKSIEVDDLDPIEALAKAVDAAERGVAFTVPIRARKGRASYLGWRSVGHQDPGATSTLIILEELLAVAAERLDVDVPETDAGSPTIPDDDPDDVDPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT84</accession>
    <name>V6DT84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5347" checksum="01D307A006EE3E9E" modified="2014-02-19" version="1">MARACEAASRPSSTARGSRWRPERSGGRQRRGWGGVRLCCAGWDSKGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT85</accession>
    <name>V6DT85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5426" checksum="1D2CFC1E47D4A3FE" modified="2014-02-19" version="1">MVISTASIPLGSVPEESGDDDCLDMVSTPRGTTQTATDDATGCQGRTSYNWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT86</accession>
    <name>V6DT86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="11995" checksum="5CA19DD6B67F4D8E" modified="2014-02-19" version="1">MDERCRDHLGTVLIVYREELGWPDTGKTAGLPASRHRCWSVQTDETVGISRCRSPEGIQTIHEYPRKLEFRTELPKRSLERSVARNYKTRPKSTLKQSSEHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT88</accession>
    <name>V6DT88_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
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    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4425" checksum="8EB6242834E4D50B" modified="2014-02-19" version="1">MSVRIVRSGVMTRSRGTSWASGSGRSDGLPPTADSGPSRTESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DT89</accession>
    <name>V6DT89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halorubraceae</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
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                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">AJ67</strain>
        </source>
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    <reference evidence="1 2" key="2">
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            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8790" checksum="F75113B5EC185E1E" modified="2014-02-19" version="1">MRLTSSLIEYFAYSRSMRTARTSCIAWYRNTRSSGNGYYIAIEIDSFLLGIRFLLGNKIKTLSVNWSNYDVLDCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX6</accession>
    <name>V6DVX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5527" checksum="A9BB2320B3AA1DD2" modified="2014-02-19" version="1">MTQHNRDVRGTVDETKRGTRGSDALTGGVKVGSSTGTAGEGQRILSAGPFRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX7</accession>
    <name>V6DVX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="5974" checksum="D5FA7B93CD943AFD" modified="2014-02-19" version="1">MNRRLIGIAGVLACVVLVGVAVAATNPTLLIAGYDTATVGPSTATPASRSRPPTPASPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ0</accession>
    <name>V6DVZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C475_18228</name>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5409" checksum="86AF1CACCB94EDDB" modified="2014-02-19" version="1">MRPNIDISHTLNGRVKDYAEQKDKSLEEAYREIIKAGLEAAEHPNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ1</accession>
    <name>V6DVZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="10589" checksum="9661250B4EDD462A" modified="2014-02-19" version="1">MTEIDQDDVSILNEFNCESCEDEIALIQFKGKYMTVGSAVVPALFGAGGYSLGGSAGVAALGTAASASWPLAAVGALLGGSAVYVAGATKDSLQCPHCDSDIEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ2</accession>
    <name>V6DVZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Circadian clock protein, KaiC</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06325</name>
        <name evidence="2" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077907.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57446at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010624">
        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KaiC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="243" mass="26794" checksum="53092E83889463A3" modified="2014-02-19" version="1">MSELVSTGVEGLDSILTGGITERSTVLVSGNPGTGKSIFGIQYLHHGVSEHGERGVYVSFEEDEADIRGAAESVGFEGFDEMVEDGDIVILDKREMLRETDFSTAVDRLLDTVEDGDFDRLVLDSLSMFQLFFDAEQEKRTYLLKFSDILKANGLTSLLINEQGAVFPDTEVGLENFLTDGNIYFIQTPTDSGVNRYVWVAKMRKQDIDTDIFPMEIGQGGITVHERAGGFSMMGGSDDRPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ3</accession>
    <name>V6DVZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06480</name>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077885.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16335at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="428" mass="45934" checksum="ED2943D3DB93A95F" modified="2014-02-19" version="1">MTDQDKRLSRRHFVGATGAATLAGLAGCSGGGDGGDGGEGALEVLHAWTGGDGATAAEALVEAFEEEYPDIEHEFNPIGGGGNQNLDAVVANRLQNNEPPSAFAGWPGPNLQRYDGVLGDVGSVWEEEGFEDVMVQEAVDLHQRNGAYRAVPLGSHRLNCLFYNTSVVEEAGVDPDSLTSVSAFIDALETVQNETDAIPMTHGVSGTWTTTQLFSSTMLGQEGYEAYMNFLDGSPDEAAVSATFESLAEILENYINDDASSIGLTESNQNIIEGNAAFIHQGNWAAGAYRNAEDFNYDEDWGFKTYPGSEGMYMLHFDSFLYPSDNPTPDTTDQFMAFVGSEAAQVAFNQYKGSIPTRTDVDMSEFGPYLQETQEDFANAEERPPNLQHGLGVPSETMTALNDVISSEFSGPYNVDAATEGFVDAVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ4</accession>
    <name>V6DVZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_07586</name>
        <name evidence="1" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20852" checksum="6157FA6164EB5A5C" modified="2014-02-19" version="1">MAPTETDTNTLPKSLRILSKYNFTDEVTVTAQSMPSDFFIRLNTLPGDLLVPGLIFFAIRDTNSEILNIGNTISGPPAVTGIIDRDRLTSPKKKTIDDIAALPRTLDIHRTDDANLTELEVVHEQRPGTKLVGSTIARTIDATEYEIVNVQTHDHRRGVSIYLHDPTHSSDHDINEERKTLADLLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ5</accession>
    <name>V6DVZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative DNA primase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">priB</name>
        <name evidence="8" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0639">Primosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="13305" checksum="369C02840ED6A597" modified="2014-02-19" version="1">MTNLIEKAERDATLSSAESFALMAFLVGIGMTPDEVVAFCADTSLDAEGIRYQTEYLTDDRGTQYPPPTCETLANYGICHNEDDHMQVAADPLSYYEKQVAAADEVTDWRAGREPDEASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ6</accession>
    <name>V6DVZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Family 3 adenylate cyclase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C451_02834</name>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="291" mass="32831" checksum="BAFAB73ACC218F3C" modified="2014-02-19" version="1">MTNCFCENISEEGDFNRAFNPYLNTAIYSIQIIRTSPYKRKLMGIDRDDVEERVEDRADDIEDRLDHIPNSYSMPDLEDMTIGSAKEFRLGIVFLDIAGFTEYASSNDYEDVLFMLNMFVPEMMETVKENDGFFEKNTGDGILVYFGAGQEDAQTAHDVLEYLADVKLVLANYVNPCLEDYGIEPIQIKAGAAFGTVYISRIGVHSLNRRTAVGTVANVASKLEDKADGHEYFVSHGLRKSLSPDCGWAEYLTDKGSFGNYRWGSDSSGWEDTHYYAFTGGWAATEWDNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ7</accession>
    <name>V6DVZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4990" checksum="2AF1133613673451" modified="2014-02-19" version="1">MLRRPPACPAGVIGRMGNSYLRSLTRLSRLIKICCPAIFALFPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ8</accession>
    <name>V6DVZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyribonuclease/rho motif-related TRAM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06395</name>
        <name evidence="3" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077895.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103175at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="18074" checksum="2A51252C52B6F7FC" modified="2014-02-19" version="1">MADCPLADDCPSFDERIEGMGCQHYGNKGGAEWCNHYDMPIYELKQQPVQPGEVVTVEVDDIHESGAGVGRTDDGFIVLVDGLLPPARAEVKIHRVKSSHATAQDVVERLPDDPDEEADDDEAVGADDGEVDEDDDEDHRRDRPDRERLGSRENFWGEVTGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVZ9</accession>
    <name>V6DVZ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hqrw_3441</name>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="17929" checksum="F898E989349C28D8" modified="2014-02-19" version="1">MFPGAEFISPESLGRCMESTDGIHKWVEQTTVYDRVRLISSTVSQPRSVQHIADEACVCEVTAREYLDRLSDLNVLLKSEQDGTPVYSPDLLHTRMKTLRDLLENHTHEELLQLKQSYVLNSTTKTYPGESRSLWNIDCRWSPTQSTITRKTKARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW96</accession>
    <name>V6DW96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_00852</name>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078024.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72034at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="17"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="30549" checksum="C2ED5F3FEA205425" modified="2014-02-19" version="1">MTETAETAETIETPPAIVAMLNQKGGVGKTTLTIHVAGALADRGLDVLVVDLAPEGALTSILGYDEAYSDLDREVSLHELLLDPSRADDVDDIIITGEEFDLLPANERMVDRTGGELNGEPRARERLKMVLDELATGYDVVLVDNMPSINVLTDNALVASDGVLIPAYAEALSVQGLDRLQKQIDSVREYFGTVRILGIIANRVEHNKQADAMLEQLHSEFEDGLKIPVFDVYKRVDLQRAIAAQERSIFAADELDSDMAEVLADVAALVETELVREAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW97</accession>
    <name>V6DW97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kynureninase</fullName>
            <ecNumber evidence="2">3.7.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08796</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="PTHR14084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="15766" checksum="AC0D42951D401A5A" modified="2014-02-19" version="1">MNMEYTPADSAGAWQIGTPPLLSAAPLEGSVELLREAGIERLREKSLALTDFLIALVDDRLPEIAVGTPRAHAARGGHVALEHPDAERLSEALTDRGAVVDFRPPNVVRVCPAAPYTSFADVLDVVDAIEAILDGGAHEKYATNDGGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB0</accession>
    <name>V6DXB0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Putative toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">vapC</name>
        <name evidence="7" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077897.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104470at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="5"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="13906" checksum="9DD84293B82F879C" modified="2014-02-19" version="1">MTLYDSSVLIDYLAGRDAAVEYVELHADERAVAPPLVLFEVYQGEVFKTGATDLDAIDEALTWVDVVETSAASARAAATLQDELRATGEPLAARDAYIAGVAALRGERLAVADADFDVDGITDRLIVDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB1</accession>
    <name>V6DXB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6719" checksum="EE4D267E23D8238C" modified="2014-02-19" version="1">MDILDFSLFGRRPFRRRFLVVFGVYLLYLNVAAAPVVRIGPEEPIEYRHIYRYISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB2</accession>
    <name>V6DXB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6388" checksum="0C26B80627491442" modified="2014-02-19" version="1">MGQHDLGVRRLRDRDYLVREPFRALLVLGTNRQYDCLDAHTRLSSPRDLKTSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB3</accession>
    <name>V6DXB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6517" checksum="74165EB30A06F753" modified="2014-02-19" version="1">MSNRFLIWLTYDAEQSHASAISWFVAFGLSRHVRRMSRCRSVLELLPIFSMITFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB4</accession>
    <name>V6DXB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligopeptide/dipeptide ABC transporter ATPase</fullName>
            <ecNumber evidence="8">3.6.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_07819</name>
        <name evidence="8" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.24" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK39998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077520.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43111at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="373" mass="41385" checksum="24B3754FB573E65C" modified="2014-02-19" version="1">MSEPLLSVRDLKTQFFTEDGTVRAVDGISFDVHEGEIVGLVGESGAGKSVATSSILRLVDSPGEIVGGEIEFKGETIFGLEEDDDGELRPRDEMLTENEMRKRIRGREIAIIFQDPMESLNPVFTVGGQLREFIEINRDLDADEAKEEAIDMLREVGIPAPESRYDEYPHQFSGGMRQRVLIAMALACQPDLIIADEPTTALDVTVEGEILEMVTDLQEKYDTSFIWVTHDMSVVAEICDRVNVMYLGEIIEQAEVDDLFYDTKHPYTTALLDSMPRPDRTVDELRPIEGVMPEAIDPPAGCRFHSRCPEAREVCREVHPEPRNLNEEGEARHAAACVKHDAFDVGYDESPPMEAEAAGGFSAGFTETGGEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXB5</accession>
    <name>V6DXB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06355</name>
        <name evidence="3" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077901.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="13052at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="18"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="444"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="549" mass="60845" checksum="BB73002AC2E4E382" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0N1</accession>
    <name>V6E0N1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1096</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000045">
        <property type="protein sequence ID" value="CDK41153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078495.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000045.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104343at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="13896" checksum="2881DE6FD7E6F914" modified="2014-02-19" version="1">MARTPRETVEEFFERMADPDERETVGELFADDAVVTVPGARFEGPDAAASFLAFLEPRYERAGKSFGRWTVDGDRVVSQGTLHGVDNDGEGFEDVRYVDVYEVSEGTIDRLDVYNDLAVEGVVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0N2</accession>
    <name>V6E0N2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05491</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000039">
        <property type="protein sequence ID" value="CDK41135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16286" checksum="88CF545BE411FDF7" modified="2014-02-19" version="1">MPNVTGWYAVPEDEAPDAGDRILLNAASESPNAVIPMSEVAPEYAPDDRALLAATFLGEGSLDRDDADLRADVRDALESWYPDREFGGLETVDVHRIRFAQFAQPPGVHADLPDSDDPEGPVVLAGDYTEWSSIQGALESGRTGAIAAADYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0N5</accession>
    <name>V6E0N5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10584</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000047">
        <property type="protein sequence ID" value="CDK41158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8451" checksum="21E23488719159B5" modified="2014-02-19" version="1">MRTRVDGDVVACTVARPTTGELQSTLDDHLVNLRVADRVIERGRAHLGNDSADTADSTHRSDSTDEPQTTDTDTPTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0N8</accession>
    <name>V6E0N8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000041">
        <property type="protein sequence ID" value="CDK41140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5571" checksum="AF9EF48C33877C15" modified="2014-02-19" version="1">MNLLVTDLRTDFDEGTPRRPRVALRSKRHPHDSRWIFNNLHSLSESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E0N9</accession>
    <name>V6E0N9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000048">
        <property type="protein sequence ID" value="CDK41163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4919" checksum="3F210C8C92CEFF54" modified="2014-02-19" version="1">MIERSGPGSDDSDPFEDEHERDDERREHQGVADLLSGDVHARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNG5</accession>
    <name>V6DNG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5257" checksum="56A4770184AA043A" modified="2014-02-19" version="1">MFRCRNKFLVMSLLDDLVFIHHDNPVGVLNHRKPVSNNGRRPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNH2</accession>
    <name>V6DNH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5964" checksum="C97EB64278C01FBA" modified="2014-02-19" version="1">MWLSCWNRSARLFFPPRALNNVVTDNDVSDRMLSVEPSVYVELFATHYTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNI3</accession>
    <name>V6DNI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UPF0061 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NP_6074A</name>
        <name evidence="9" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK37819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="464" mass="53742" checksum="DDFB7D30C6D0CEA7" modified="2014-02-19" version="1">MTFSFDTSYKDLDSRLYSTAKPKDVDNPEVLVVNENLCNDLGLNREELTSQILSGQDLLEEPIAQAYAGHQFGTYTVLGDGRAMILGEHIHNNSRYDIQLKGSGRTTYSGRGDGNATVSSMLREYIYSYAMQNLGIKTSRSLAVIQTEESVRRRRVEPGAILVRVMKSHIRYGTFQYVADKATDEIKRFTDYVIDRHYPYLNNTDKKYVNFFDEVMTSSIEMVIDWMRVGFIHGVMNTDNMSIDGETFDYGPCAFMNYYDEDTVFSSVDRTGRYSFGSQKNILKWNINRFAESLRPLFEGSSRVFDELEAKLDNFEEIFDTKHYNMMKKKLGINSDGEEKIVNQFLDWLRKSRADYTNTFIELESPGSFDDAVYSSEGFKDIRRELSGIGLDERMMKQMNPRYIPRNYLVEEALNEYLEKEDMSKFNNLLAVLKNPYEPNVTNSQFQQPPPEEFDTEYTTYCNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN0</accession>
    <name>V6DRN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport system inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_01116</name>
        <name evidence="6" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076576.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42250at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="92"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="34198" checksum="F8F58C3DE7424C11" modified="2014-02-19" version="1">MSVASYLEDRLDRDVDREKLTAILVFMLPGLTLFAVFSVGPMLYSAVGSFFTWDGFDIAQFAGFETWIATFQDDAIINWSNLLAFEYPMGALPQNIIWMVVHVPLSTFLGLGLALLFADLRGRSILRSMVFLAFTTPTVVIGLVLLFVYDPQAGIFNGLLRSIGLKSLVRNWVQEPQIAIYALVLGGVWVQTGFSMLLYSSALAGIDPALLESARVDGAGRFRRFKDIIWPLVKPVTAVVVIMSMIWVIRIFAIVYAAGGPSGGPGGVFSVLGLEVYQAAFSTPIEYSKAMVVALIELVIALPMAWYIASMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN1</accession>
    <name>V6DRN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_01336</name>
        <name evidence="8" type="ORF">BN903_148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="194" mass="20742" checksum="B17E71C5A2752A56" modified="2014-02-19" version="1">MRTVSETSTGKLAEEFEVVHAKVNYGMSLRDALVEFNNAYAVPRLARTVKLITEAQEASSQITDVLTTAAQASENQDDIERERKSRTRMQVAIIVMTYITLLGVMAILQTQFIDVMGDLVSQSGGGDSAGGAGFGGGGSIDPEVLSMLFFHAVTIQAILSGFISGYIRDAELVSGVKFAVVLVTLALGVWIYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN2</accession>
    <name>V6DRN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4358" checksum="E77A6BB145D886E5" modified="2014-02-19" version="1">MDTEVTRDALAWVDESETVLLAAPAPEIDITHLITNRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN3</accession>
    <name>V6DRN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01401</name>
        <name evidence="2" type="ORF">BN903_156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="28146" checksum="067A99BF36FA3DE4" modified="2014-02-19" version="1">MTVPLRHFVVGLALLGSALLVGIGLTVDAVPGLGGLVHVHLFLVGWVCVTIMGAMTQFVPVWSGTTLRSRRLANVQLALVVAGLVGFAAALALGRLSWLAGFGVLLLAGFWTFVYNVGRTLATLDKFDVTERHFAVALAFFVALTGLGVLLAADLESGFLAGLGVSHAGVRGAHVTLAVFGAVLTTVYGALYQLATMFTQTELRGIDHRLRAVEXXXXXXXVGVFAVNAVLVIRRHAPGSLARVALGRFAPSRLSGEGDDAADEVTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN5</accession>
    <name>V6DRN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5211" checksum="24BFEE79BB8778A3" modified="2014-02-19" version="1">MLLPDIDMSTNTNIDNSTGRLGVGQKYQRFSKRFSGPVSRPVSSVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN6</accession>
    <name>V6DRN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_01428</name>
        <name evidence="2" type="ORF">BN903_153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076607.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104116at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="256" mass="27590" checksum="9EFA6179AA1C3E08" modified="2014-02-19" version="1">MRGLGDAGFRDDDRGVSETVGFVLVFALIATTIAVTFTVGLGGLEDAQLAERDNNVERAFDVLHDNLNDLSRDGVPNRATEIRLGGGRVSFDRESEFRLNHTGTETAITEGGSITFHGTGDTRIVYENGAVFRMQGDDGVMIQEPDLLVGDTIVYSLYGLTGPADSVGGDRTVLVTSERTDRDVPVDARASGANITLSINSSQASVWERYYGDLAGEHDKISMTTDGPADITVTFVADRYDRFVAHRTIADVGFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN7</accession>
    <name>V6DRN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter-related protein</fullName>
            <ecNumber evidence="7">3.6.3.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_14972</name>
        <name evidence="7" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.36" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075804.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64935at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="17"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK37863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="260" mass="28374" checksum="8D50CA2AB085B0D4" modified="2014-02-19" version="1">MALSSESPVNRESREKITVQNVSRAYDSTQALEGVSLSVGEGEFCCIVGPSGCGKTTLLRAIAGLDDPDTGSILVGGDPVTGPGLDRGMVFQEYALFPWRTVRGNIRFGLDRPACGCPDCEARARELIELVGLDGFEDAYPKELSGGMKQRVGIARALAPDPEILLMDEPFGSVDARTRDRLHTELLDIWAQTEQTVVFVTHDIDEAVKLADRVVVMDAEPGMVQSTVSIDVERPRERTAHDFVEYVAQIRAELGEPEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRN8</accession>
    <name>V6DRN8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L39e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpl39e</name>
        <name evidence="6" type="ORF">BN903_161</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_L39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_L39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_L39e_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="SSF48662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7561" checksum="212B5DC6CCBFFE60" modified="2014-02-19" version="1">MEGVLCDPRKVCATMGDKSKAQKKRLAKAERQNTRVPAWVMMKTDMNVTRNPKRRNWRRNDLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP0</accession>
    <name>V6DRP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_01156</name>
        <name evidence="3" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076584.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113042at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10872" checksum="E4DC9F49C84C736E" modified="2014-02-19" version="1">MSSTSTTDDRGDRRGSLAQMFDPEELRRRNLVSLGMDVLILATTGLLSILFTMGFWPAAIGAIPMITLLYFGWASSKAFFVAQVLAIGVALLGTVTGVLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP1</accession>
    <name>V6DRP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_07387</name>
        <name evidence="2" type="ORF">BN903_158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="352" mass="38461" checksum="B6CB8A0609D72530" modified="2014-02-19" version="1">MRVTPQTVRDEHAWVRDRADAVVPILNDTRDRLGRLFETDVDAVSPEAYRREVDVVFADGEVAVNVAACVALLRDLDVTGDYPGFVVDEVLGRELAATVAGGRPLSLLAQATFHFADLHVDRDATAEGDGRGAGTAGADDLDAALAXXXXXXXPRGRRPLLIRPDVDETSPTVITSYSIHYTKLXEDGVRDEFRLDRAGTVAADQLRVLEHRVELLVGVRPVDSLALLGVGLLLRALREVRLHRSRFDDDHVDAEVRDLVAQRVGHRFEGELRPAVHAAAGHRHPPGDRRDVDDGSVALAPHRGQHRPDQPVWPVHVHVELVVDPIGGDVLDRTELTVAGVVDQGVDRSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP2</accession>
    <name>V6DRP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cobalt ABC transporter ATP-binding protein</fullName>
            <ecNumber evidence="8">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_14992</name>
        <name evidence="8" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075808.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92866at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="9"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="293" mass="31377" checksum="524016F2F3A29972" modified="2014-02-19" version="1">MSQDDSPLVELQCEAHTYPDGTVGMHDVDFSVYPNEVVALVGGNGAGKSTLLEHLNATLVPDVGELVVDDTPITEDNKSYARKEVGFVFQDADTQLVAPTVLDDVMFGLQNYGVPSDEAKERAREALATVDASHLEDRIPHYLSGGEKRLVGLAGVLVLEPSVVVLDEPLAGLDPERSQLVADRIEQVHQEGISVVLSTHDLDFAATVADRVCVMADGNVVGNGTPREVFYDDALLAEANLHAPSTVRIARDTGLGEKAQPVTESELVRHLTAAVEDVNSNQVSSVDTTQTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP4</accession>
    <name>V6DRP4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">fumC</name>
        <name evidence="6" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076587.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26165at2157"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="4">
        <location>
            <begin position="13"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="5">
        <location>
            <begin position="408"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="2">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="324"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="469" mass="50063" checksum="47F4570E4CD3DFBB" modified="2014-02-19" version="1">MGDDYRTEEDSLGEMQVPADAYWGAQTQRAVENFPISGIGMSRRFVRALGVVKKAAAQANRDLGLIDDDTAEAIVAAADEVIAGEHDEQFPVDVFQTGSGTSSNMNANEVIANRAAEIAGAEIGDRVVHPNDHVNYGQSSNDVIPTAMHVAALEAVEKDLVPALETLHAELEAKETEFDGVVKTGRTHLQDATPIRLGQEFSGYRTQVAKGIERAENAQSNLRELALGGTAVGTGLNTHPEFPELAAEYISDETGTEFREAENHFEAQAAHDAMSEGHGALRTIAGSLNKMANDLRLLASGPRNGLGEVEQPENQPGSSIMPGKINPVVAESVNQVHKQVVGNDAAVSAGAARGEIDLNLYKPVIAHNFLESAELLSNVAATFGERFVAKLEANEEFCETRVEQSMALATALNPAIGYDKASKVAKKALAEDKSVKEVAVGEGYLTEEEADEVLDPEAMTHRVILGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP5</accession>
    <name>V6DRP5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L18Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">50S ribosomal protein L20e</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">50S ribosomal protein LX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C463_07452</name>
        <name evidence="3" type="synonym">rpl18a</name>
        <name evidence="3" type="synonym">rpl20e</name>
        <name evidence="3" type="synonym">rplX</name>
        <name evidence="5" type="ORF">BN903_166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Binds 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629917.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="GeneID" id="65212944"/>
    <dbReference type="OrthoDB" id="125208at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_L18Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="50S_L18Ae/Ribosomal_L18a/L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_L18a//L18Ae/LX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18A" evidence="4">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6694" checksum="AA52703041FD1A03" modified="2014-02-19" version="1">MSTYTVSGRFQSRDGFQPFTKDVEAENEDLARERIYTNVGSQHNRKRTQIEIEEVSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP6</accession>
    <name>V6DRP6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translation initiation factor 6</fullName>
            <shortName evidence="3">aIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">eif6</name>
        <name evidence="4" type="ORF">BN903_163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076618.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70525at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="PTHR10784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="221" mass="22891" checksum="20ACB04E90C696E4" modified="2014-02-19" version="1">MLRATFTGSSYVGVFARAVDDLLLIRPDVDEDLADDLGAELGAEPLLTTVGRSNTVGALATGNEEGILVSSRATEREKDRIADVAGVPVSELPGEINAAGNVVLANDYGAYVHPDLSRESIQTIKDALDVPVTRGDLGGVRTVGTAAVANNTGVLCHPQSTESELQAVEEALDVRADLGTVNYGAPLVGSGLVATDEGYVVGEDTTGPELGRIEETLGFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP8</accession>
    <name>V6DRP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="7508" checksum="19434AF3E0AFCE87" modified="2014-02-19" version="1">MSISATRSANASNASRSSRTRRRSPRQAASASRTYANASSAITPPNATAATTSGSVTTALSSHQAFEHPAAVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRP9</accession>
    <name>V6DRP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11585" checksum="8C30DAF67DC0329F" modified="2014-02-19" version="1">MSAVLPRCLLEPGEHVLRDGGPVARLVGDTECERVPQPSAHRVPLRGDRRVYRLTFRLGRPGCVSTTLSVTGATAGRSGRDRRRAHQECTSRRRHRCLGYPKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRQ0</accession>
    <name>V6DRQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein MoaB</fullName>
            <ecNumber evidence="5">2.7.7.75</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_15017</name>
        <name evidence="5" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.75" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075813.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108340at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061598">
        <property type="term" value="F:molybdopterin adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012245">
        <property type="entry name" value="MoaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43232">
        <property type="entry name" value="PTHR43232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006443">
        <property type="entry name" value="MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="4">
        <location>
            <begin position="31"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK37873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="194" mass="20273" checksum="2014BD977060BC52" modified="2014-02-19" version="1">MTGSHSELPSPADRRTTDADGHDCVDPLGVAVVTVSSSRGTATETDPSDPGGDAVENILAEASHVVTSRLTIPDDYVQIKTTVGECLERPDVDLVVTTGGTGVTVDDVTPDAVSELFDRELPGFGEAFRRLSWEEVGTRVVATRATAGIARDVPVFVLPGSVNAVELATAEIIAEEAPHLAGLATRHTVGEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRQ2</accession>
    <name>V6DRQ2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="4">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">ftsY</name>
        <name evidence="7" type="ORF">BN903_168</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076624.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90641at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="176"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="258"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="316"/>
            <end position="319"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="366" mass="39010" checksum="C157F6DF35375223" modified="2014-02-19" version="1">MFDGLKDKLSGFREDVEESTETEEEAPPEADASAENDAADESGAPAADAPEAAAADRAEADSDDEAGSDDEPSTFQRAKAFATGRIIIEEEDLEEPLWNLEMALLESDVEMSVAEQILDSVRESMLGESRKQVDTTGELVEAALHDALVDVIAVGQFDFEERIAEADKPVTIVFTGVNGVGKTTSIAKLSEWLGDRGYSSVLANGDTYRAGANEQIREHADRLGRDLISHDQGGDPAAVIYDGVEYAEANDIDVVLGDTAGRLHTSDDLMAQLEKIDRVVDPDMTLFVDEAVAGQDAVNRAKEFDDAAAIDGAILTKADADSSGGAAISVAYVTGKPILFLGTGQGYDDLALFDPEELVESLLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRQ4</accession>
    <name>V6DRQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type transport system ATP-binding protein (Putative substrate zinc)</fullName>
            <ecNumber evidence="7">3.6.3.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">znuC3</name>
        <name evidence="7" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.25" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075817.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87509at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="20"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="52"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK37878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="28227" checksum="377CF4FFCC4BAA88" modified="2014-02-19" version="1">MTTETAGSESPRERSTEPVVSVDDVSFAYGDLPVIESVSIDVEPGAFLGLVGPNGSGKSTLLNLMLGLQKPDTGAVRLFGEPATEFDAGERIGYVPQNATTAAQRMPVTVRELVTMGRYPRRLVGRFSDEDRRAVNDALRAVEITDLTDRRVGQLSGGQRQRVFIARALAAEADLLALDEPTVGVDAESREAFYELLADLNDSGLTIILIEHDIGVVTTYASEIACLNRRLYFDGDPEDFVATDALAAAYGTDQHVLTHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRQ5</accession>
    <name>V6DRQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9567" checksum="BBA56E153476830B" modified="2014-02-19" version="1">MRGGDLIEYSRVSSGVVRSDRFPLDVDCVDRSDRSEPNRHRIRLCPTHACYSLSVILVLSPPPKQSRFRDNCSSAVQIGDYTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRQ7</accession>
    <name>V6DRQ7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ORF">BN903_145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with TatC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9713" checksum="B9AC46E7A5A6DF0C" modified="2014-02-19" version="1">MIPLFGGLPVGPELLIILLVLVLLFGANKIPKLARSTGQAMGEFKKGREEIEEELKEMDDDETESTLDNEDDEFEDLETETEKETSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRQ8</accession>
    <name>V6DRQ8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">moaC</name>
        <name evidence="6" type="ORF">BN903_181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoaC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076636.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104538at2157"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01419">
        <property type="entry name" value="MoaC_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_A">
        <property type="entry name" value="MoaC_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023047">
        <property type="entry name" value="Mo_CF_biosynth-C_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="5">
        <location>
            <begin position="35"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="95"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="179" mass="18914" checksum="E2BCA15A86BD941E" modified="2014-02-19" version="1">MSEDPETDAEPNGSARATADGDELTHTTADGDVQMVDVGDKPDSSRRAVARGEIRLTPETIAAVEADAVEKGDVLATARIGAVQAVKHTWETIPMCHQIPITNVDTDFSVGDDRIELTVAVETTGKTGCEMEALEGVTTGLNTVWDMVKAAEKDADGGYPDTGITGVEVVEKRKETVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS01</accession>
    <name>V6DS01_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BFN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_04428</name>
        <name evidence="3" type="ORF">BN903_242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076684.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81987at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="2">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16303" checksum="DDF4ABAA3486A302" modified="2014-02-19" version="1">MEHEAEVVGVGAGSAPSGDVPAVILSARGEYVPIFVSGDQAQSIGMALEGEPFDRPLTHDLLVDILTEFGGAIDRVRVDDLRDGTFYAKVDAERYDDGEPERFVFDARPSDALALAVRVDCPIVVTDEVIDEAGRPPDSIRFGGDGDPSEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS04</accession>
    <name>V6DS04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C496_23121</name>
        <name evidence="1" type="ORF">BN903_178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075872.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130243at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8699" checksum="C4AC057FDAA46567" modified="2014-02-19" version="1">MSNDVPDEQTARELANTYADSECIGQLGDVTDIEERDTEWLVEFETHTLSDTYTHHVRITKSVGNVISHDRSSRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS06</accession>
    <name>V6DS06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6185" checksum="53491336080F561C" modified="2014-02-19" version="1">MPFCPARSMLRLLSSILSCHVKPRDTRRFFGLGFSPTPSYVSVNQKQSSERRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS09</accession>
    <name>V6DS09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_15642</name>
        <name evidence="1" type="ORF">BN903_268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="7164" checksum="087141ED1CC78FD0" modified="2014-02-19" version="1">MFYFPDDEPPRMPQVHLDEETVERLDGLRVDDEEYDEIVSELINIYEAEELTLFRGSDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS10</accession>
    <name>V6DS10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Insertion element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03893</name>
        <name evidence="2" type="ORF">BN903_188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="2"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="13477" checksum="0849C277D27CDA91" modified="2014-02-19" version="1">MPAKSADESTIRLLLAGRQQEPLTVYTDGFRAYDPLEEDENFEREYVVHGDGEYADDTIHVNTCESHASLARRWLSPHRGISKDRLTQYFRAFQLRRELYRKPGRKALKHAVKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS11</accession>
    <name>V6DS11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_13207</name>
        <name evidence="7" type="ORF">BN903_275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076710.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122629at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="10060" checksum="CE17750FA8457369" modified="2014-02-19" version="1">MAHDSVKLYSAIYVALLVAATLNFLLFESSFVEFTYAQAVAGTLVIATVKTLLIVAYFQHLRWENRSLTYLMGMALALTMLLMAAATYSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS14</accession>
    <name>V6DS14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halar_0391</name>
        <name evidence="2" type="ORF">BN903_193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="7966" checksum="AAA5F52377DACEF6" modified="2014-02-19" version="1">MTQKTIGQNTGQSGRVNLSGPELAQFDAEVGDPIKVDVAESKGIAKAIIENSIEEEFVIVSKPVNTSSSTEETDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS16</accession>
    <name>V6DS16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4980" checksum="1D9B9A555E9140D7" modified="2014-02-19" version="1">MRRSRTAADRVRSSLLRPIVLAARVRRFSVTRSSKNTAMIKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS17</accession>
    <name>V6DS17_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">leuC</name>
        <name evidence="15" type="ORF">BN903_255</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076695.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15714at2157"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="14">
        <location>
            <begin position="8"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="289"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CDK38961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="473" mass="51262" checksum="4651C43615EE0B2E" modified="2014-02-19" version="1">MSEGTLYDKVWDRHTVTRLPTGQDQLFVGLHLVHEVTSPQAFGMLKERGQEVAFPERTHATVDHIVPTGNRDRPYRDEAAESMMAELEANVRGSGIDFSDPDSGDQGIVHVIGPEQGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATGCVAMEKQKVRKIEVTGELGEGVTAKDVILTIIGKLGTDGGVGYVYEYAGEAIEDLGMEGRMSICNMSIEGGARAGYVNPDETTYEWLEGTDAFEDDPEEFERLKPYWESIRSDDDAEYDDVVTIDGSAIEPTVTWGTTPGQTAGITEPIPDPEDLPEEDRDTAKRAQKHMRVEPGDTMEGYEVDVAFLGSCTNARLKDLREAAAFVEGREVDDDVRAMVVPGSQRVRDAAEAEGIDEVFKEAGFDWREPGCSMCLGMNDDQLEGDEASASSSNRNFVGRQGSKDGRTVLMSPIMVAAAAVTGEVTDVREMEEVATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS18</accession>
    <name>V6DS18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="17134" checksum="8F8B52B81103B459" modified="2014-02-19" version="1">MSTSSLLLEVYIIILSHVTMVFTYFVSSGAEKWVLVKSFRIVCRYPRLRRNLLPAVEGGPPVPRAGLPNGNRRIELPDPSGRGPDRSLELLDGLEVAFRPHELGQPSRRVTRRTAEVGPEILKIGGIVLPLLATLWTDESDERVDHVPAYSGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS19</accession>
    <name>V6DS19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04668</name>
        <name evidence="2" type="ORF">BN903_278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.28" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018479">
        <property type="term" value="F:benzaldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6498" checksum="F20954926C74AF4D" modified="2014-02-19" version="1">METGNVHINDQPINDEAHVPFSGIGASGVGHYNSDAFLDEITETKWISIQHDPREYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS20</accession>
    <name>V6DS20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5550" checksum="D019012D5E713C42" modified="2014-02-19" version="1">MPNNALEANLRGIGDGARLEQLAVDLLGRDGYDVDPTSVRGPDGGRDTLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS22</accession>
    <name>V6DS22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_13918</name>
        <name evidence="2" type="ORF">BN903_286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4962" checksum="AC4DE14C78C4C0D0" modified="2014-02-19" version="1">MFGLPAGEFLGGIAIAVFGVGTWAIGLGVAYFLYRRWRGDGPRSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS23</accession>
    <name>V6DS23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5084" checksum="9C5BB1E34526A919" modified="2014-02-19" version="1">MSKILTGPISTLEAIVPWKNSIRRGVRRSLRDVCHRFTTRRSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS29</accession>
    <name>V6DS29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C487_17685</name>
        <name evidence="2" type="ORF">BN903_208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075890.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121287at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="17324" checksum="E514C24FF50B1BBF" modified="2014-02-19" version="1">MTTAERETTEPRSFTPITEHPLPFSDGLSDFLESHPQFDADDDVGVDELHEEYTTTLADNGFWRVFRVDLHGYNNWVYLWHSEYGDGLKIPTGEWQFGNFAEVFALLLSDEPGTIDDHTGDGCPYCQGTLSSSLQQSGSHKQTCTRCGRSRIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV0</accession>
    <name>V6DVV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding HSR1-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_07235</name>
        <name evidence="4" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077837.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66209at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NOG1_N" evidence="3">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="NOG1" evidence="2">
        <location>
            <begin position="224"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="327" mass="36821" checksum="DB54A99C99D04A2F" modified="2014-02-19" version="1">MIFEGLPTTPRAEELVDKAFSRAARAGRAKRGHEAQESMLRTAGNVLSDNLENVVTSWPDFGFDVDPFYYELADAIVDVDRLRQALSQVMWASRQIEDLRDEYTTKIRNSDVDTARKHRKQAFARMADVMDQIEDDLRYIGDSRDQLKVLPDIRPDEPAIVVAGYPNVGKSSFVNRVTRASNQIAEYPFTTKGVQIGHFERNHVRYQIVDTPGLLDRPEEERNDIERQAVSALEHLADAVVFVLDPSGDCGYPLDVQLELREEVRELFGADVPLLTVANKHDRFEAVRAESVDATMSVTEDENVEAVLDLAVDAVGYEPDLPTRDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV1</accession>
    <name>V6DVV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4831" checksum="A5740EA73010D357" modified="2014-02-19" version="1">MTNGRNIAVIGRRPSPRNCELTIRTRFYVTSHCLTVDLLQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV2</accession>
    <name>V6DVV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4599" checksum="4C9EC0FFD25C89BC" modified="2014-02-19" version="1">MSIERKLRGIAGGASPRKVPKRQRGRQWSSSSYTHAEVSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV3</accession>
    <name>V6DVV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_07215</name>
        <name evidence="2" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077838.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123698at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8905" checksum="8B29CAB240DBBDD0" modified="2014-02-19" version="1">MISPLVIDTFLLNYHLGHVILFGLVVSLLGAAPLKSQKMFASILAVFGVVFLAAPYTTMPATFVLVGIPLILIGTLLWTMSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV4</accession>
    <name>V6DVV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5888" checksum="A640DEF60306C0C6" modified="2014-02-19" version="1">MGEGRSEGEGQSESEERSTGEERLESEGSDRMDVSCSDGRRRKFPGENGTKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV5</accession>
    <name>V6DVV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_06735</name>
        <name evidence="2" type="ORF">BN903_192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077064.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81422at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="196" mass="21350" checksum="C1DA0212643C8267" modified="2014-02-19" version="1">MRTLDETDREILRLLLADARRPYSDIAERVDLSAPAVSDRVDRLREVGVIEGFTLRIDGDALSDGLSVLAMLSVAPADAERVHEAVADHERVEHAFLTADGEVTVAARIEEGTARDLVDDAVGLDAVRELSVRPVDAHEWSPAVGDADLAVECVECGNTVTAEGESARIDGTLYHFCCGSCRENFEQRFDRIEEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV6</accession>
    <name>V6DVV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5255" checksum="791AD0C0BE1F8D1E" modified="2014-02-19" version="1">MYGRVTGIVKPPGVGENRVYPIDEEDDAEGEEGSTGGDDGSEDDGKRGGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV7</accession>
    <name>V6DVV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_03871</name>
        <name evidence="1" type="ORF">BN903_197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7733" checksum="87446425CEDB6D99" modified="2014-02-19" version="1">MTFAVPDPDASLLDAMSGFTVAKRRTNVFPLVYDTEGERLHRHEVPRLKGRGIYRRQAEDAERLFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV8</accession>
    <name>V6DVV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_16731</name>
        <name evidence="3" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077824.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87728at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="15"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="178" mass="18785" checksum="F6D8A2351E47A9E8" modified="2014-02-19" version="1">MRRRHLLAGLASVGALGGAGAVATGGVPDVLGDGPEPVEPVTLDTVDAPGSRDGEVTIPAEGRPTFVDFFATWCGPCEKQMPGLVAAHDEIDDEVLFVSVTPENVGGSVDPKTVVEWWKNHNGDWLVAADVTAELAAKLNVQNYPTAVAIDETGRIRWSDYGVHTAEEIVTGIETALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVV9</accession>
    <name>V6DVV9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amphi-Trp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02287</name>
        <name evidence="3" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123098at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027598">
        <property type="entry name" value="Amphi-Trp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20068">
        <property type="entry name" value="Amphi-Trp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04354">
        <property type="entry name" value="amphi-Trp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amphi-Trp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10243" checksum="E70C627327909478" modified="2014-02-19" version="1">MTEKVLFESESRRSREEIAAYLRAVADSLDAGDAITLSRGGESTTLEPPARLTFEVKAEREGPADGPGELSVEFELEWNEDGDEAGADGELRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW0</accession>
    <name>V6DVW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6186" checksum="8A5B2EF6C49EE25F" modified="2014-02-19" version="1">MSGGSRISLVVPCRSRSHRRWWTVRREEVRLEGGQRRSAMFGCYAGRELALDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW1</accession>
    <name>V6DVW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6126" checksum="B32F0CE9C010BF66" modified="2014-02-19" version="1">MNASRTGDDSSAGEPKREFRHPSASDAPDGEAQSRRRPVRRPVAFAFPMIATTDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW2</accession>
    <name>V6DVW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8257" checksum="4BBFD71063ACCD91" modified="2014-02-19" version="1">MPRLPHFFRHRGAVGGVADHFSHALRQPARPLRGYAARSFSHTRRLLFELKAHSLQVLALILPFRCRSVVDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW4</accession>
    <name>V6DVW4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02429</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077860.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112213at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8939" checksum="FC145C9A68D05DFD" modified="2014-02-19" version="1">MVDILAENLSGKAVMSSDGTELGDLYNITMNLESGELNHLLVSPHEQLRPGRVDFDVDEMGRLRVPVANVQAVKDYIVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW5</accession>
    <name>V6DVW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Formate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_07225</name>
        <name evidence="8" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="7">
        <location>
            <begin position="333"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="551"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="581" mass="62582" checksum="1330EBB314B6240F" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW6</accession>
    <name>V6DVW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4936" checksum="3849258A30DBD2E9" modified="2014-02-19" version="1">MWPEGDGELFQSSGRLLINSRRQIGRQHHRSPSRSAVRCWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW7</accession>
    <name>V6DVW7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative nickel-responsive regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C472_02474</name>
        <name evidence="12" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Transcriptional regulator.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="8">Binds 1 nickel ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the transcriptional regulatory CopG/NikR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077866.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010045">
        <property type="term" value="P:response to nickel cation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00476">
        <property type="entry name" value="NikR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022988">
        <property type="entry name" value="Ni_resp_reg_NikR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0533">Nickel</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RHH_1" evidence="10">
        <location>
            <begin position="4"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="NikR_C" evidence="11">
        <location>
            <begin position="54"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK40462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="17969" checksum="F4AB16315F59534D" modified="2014-02-19" version="1">MTVVSVSMPEELLERIDQFSDEHGYTGRSEVVREASRNLLGEFEDAKLEDRALMAVVTVLFNYETTSVEERMMRLRHEHEGIVASNFHSHVGSQYCMELFVLEGGLEEISTFVGKVRATKDTLTVDYSVTPVDEFGAGPLGEGGAHAHGHGSSGDTEDASTGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW8</accession>
    <name>V6DVW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thiol-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_07200</name>
        <name evidence="1" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077840.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88489at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15603" checksum="41438DF2A2B34176" modified="2014-02-19" version="1">MDGDIPEDAAIILFDGVCNLCSGFVQFVHPRDPEGKYRFASLQSEVGQALLAEHDLPTDEIESIVLIEDGESYVKSAAVIRIATGLGGRYRLLSPFRYVPAPVRDRVYDFVAEHRYRWFGKKDRCMMPSGDVESRFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW9</accession>
    <name>V6DVW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_03806</name>
        <name evidence="1" type="ORF">BN903_207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4678" checksum="24EBAD68734BD6AB" modified="2014-02-19" version="1">MPDGRTANESAVHADLVRDASEDARIELDGETVYRNGSFLIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX2</accession>
    <name>V6DVX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_16174</name>
        <name evidence="2" type="ORF">BN903_212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="22292" checksum="F86F6319FBBBB4FF" modified="2014-02-19" version="1">MARNIKEIYDADIAANIEGWTSAWFSAYGDATIASLPSAAWMEGTLRAELPDTAGDWGVFKIPALESGGPRASNWGGSNLMIADQVSDEAQARGWDYMEYSLATEEMQLAMYDEYGLFPALETVYDDPVFDEELDFYDGQPARALFAEVAQDSPGYRFTADTPEVSQAIETELQRMINGEQSPEEAVQAAAETVAENTDRDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX3</accession>
    <name>V6DVX3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_07115</name>
        <name evidence="2" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077848.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38672at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046260">
        <property type="entry name" value="DUF6293"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19810">
        <property type="entry name" value="DUF6293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6293" evidence="1">
        <location>
            <begin position="3"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="325" mass="36397" checksum="B2C98F288A04FC8A" modified="2014-02-19" version="1">MQTHIVPVGFDYDRMIAPLIRDQFDVDRVILLEGTVGSEGNVEYSRNIARKLEQDFQNLLGAETVREKLTDVYDYDAAFERAYDLINAELDRDGGAAEDAGDAAPPADEREVWVNLCSMPRPVSFAFATAAHSIMVERQADRDRIHTYYTAPEKYLETELAEELRATRDLLRDLDAGSDADALAEAGVDPDRVSDRLASTTDLLAEFDERGTTIGAKRIGDSHVIELPVASFQNVKPFEELVLFTLGEHGEFESVSELAEALADELNEEYTDSFRSKVIYNVDRLGPGGKGYIEREEHGKSYRTSLSRIGRLWVRAHADDDRDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX4</accession>
    <name>V6DVX4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="21903" checksum="F37DBF88E70EF638" modified="2014-02-19" version="1">MSPRGRSGFSTPHCDGSLLQNSYLMPIYVLNMVAPSTLLTAFNTLLILGTIGLGISTYIFQKRTSLRESLEQLDSLWVEHRREYIGVFLHEFSYLPLLRENAVLKFYVRSPTPEEKANVGMIRNAENLIRDTFGKAPEDFLEYDRVTEAWDDESGLYLKTNTVDAVEVRQLAEQIQVDLELSIIDDDEIPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX5</accession>
    <name>V6DVX5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C464_17237</name>
        <name evidence="10" type="ORF">BN903_217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077079.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40988at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="197"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK39443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="430" mass="47051" checksum="DB70C88E69CCBD09" modified="2014-02-19" version="1">MASTTTTPDEPQEEPTEEESALETARRQLQHAADHLDIDPNVVERLKYPKKVHEVTVPIERESGDVEVYTGYRAQHDSVRGPHKGGLRYHPGVTREECVGLSMWMTWKCAVMDIPFGGAKGGIAVNPKKLTDDEKEQLTRRFTDEIRSAIGPTKDIPAPDMGTDPQTMAWLMDAYSMQEGETIPGVVTGKPPIVGGSEGREEAPGRSVAIVAREAIEYYDRDAEETTVAVQGYGSVAANAARLLDDWGATVVAVSDVNGGIYDPEGLDTHAIPSHDEEPEAVTHQDAPEAVTNEELLKLDVDVLIPAAIGNVLTADNADDIAAEMIVEGANGPTTTTASEIFAERDVPVIPDILANAGGVTVSYFEWLQDINRRSWSLERVNDELETEMLAAWQDVREEFDARDVTWRDAAYIVALSRVAEAHQTRGLWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX8</accession>
    <name>V6DVX8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine_BP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02384</name>
        <name evidence="3" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077856.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126214at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="SSF89957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00106">
        <property type="entry name" value="TIGR00106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine_BP" evidence="2">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="10884" checksum="C2E2F2863A171E3B" modified="2014-02-19" version="1">MTAIAMLSVAPVIEGSMAEEVAKAVAALDEFDVSYETNPMGTVIEADDAETLFAAAAAAHEAVDGDRVSTFLKIDDKRTSDATAADKVTAVEDHLGREAKRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVX9</accession>
    <name>V6DVX9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_06490</name>
        <name evidence="6" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077883.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46692at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="93"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="314" mass="33754" checksum="3F2B8D7A5EFE9981" modified="2014-02-19" version="1">MNDDTRTDGGAVSKADPGASAGVFSGIDGYRALLYLGLLGMLSFFLIPIESGLVTSFKTPSGVSGSLPFTPPTGSTFTLEKWQAAFDALGRGLINSALYAIPATVISALLGSFAAYGLTQSNWKPRYKAPILALFVAGVFIPYQAVLVPLSQFWSMIPLEESLSFLWGLGINDDYTGIVELIITHVAYGLPICTVLFRSYYKNMNEEMIEAARLDGASIRRIYRRIVLPLSGPMFAVVLIYQFTQIWNDLLFTLVLVQTESSAAAPIVLILAGLGTSLEGQDFALRMAGAFIAALPTLAVYIAFGEEFAEGVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY0</accession>
    <name>V6DVY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="17343" checksum="102922D3D625887A" modified="2014-02-19" version="1">MDARGRAHGLELADERSRVDAGVSLGDHDVVGSHLALVDRGGGLRGFELLEEAERVVVGADERHLTADELRQRLDPVVDLLKGSVRERVSAHADGGRAVKLPAHGLKLAARNAGHADDPDGVVRVDKVDEFVDLLAFPLGDRLGLPDRAHTGTSFAGPIVVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY1</accession>
    <name>V6DVY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12505" checksum="B7757EEFA4BABF14" modified="2014-02-19" version="1">MILRGTRRGLRSLHDPLIVRVLGLDSVERMRGERRRDGVVERLRPSVAERVRRELLECVHARRSAGRLFNRSVACDRMARRKSVLPELRPVATGHAEIYRTAPLTPGSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY2</accession>
    <name>V6DVY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="10403" checksum="E24F7C4ACCC1DED0" modified="2014-02-19" version="1">MNTAEAPAARRAHARCALQSLTPFAPSSASVACARLAAAPSIPTPHSTATAPHTSPASSVAVASLRRLTPSRGAPRALKRALGGARHRTDLAEYSLRYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY3</accession>
    <name>V6DVY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06405</name>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077893.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="137738at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="122" mass="13016" checksum="5CB75F55D90B4BA7" modified="2014-02-19" version="1">MPSSRRVVEAWIALCLTVGQLTSFAVRTASSVSPTVEGIAGFGAPLAVALGLLRLRPELDVGRLWRFAFTAWGLLILMMVASLGGRLIGVSFDAYESYSFPLAVAVALLMEPVYESGALPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY4</accession>
    <name>V6DVY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02514</name>
        <name evidence="2" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077870.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129526at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8730" checksum="51BAE29A652FE4B1" modified="2014-02-19" version="1">MFPAPFRLFFAVVPLLVAGGALAMAAFPRRLTRWNLRSADGSTETIEPSDTRILLMRVMGVVVAGLALFMLYTSFRILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY5</accession>
    <name>V6DVY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10848</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077898.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003847">
        <property type="entry name" value="Put_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02697">
        <property type="entry name" value="VAPB_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="8001" checksum="67D1F55A864AB863" modified="2014-02-19" version="1">MSKSIRVDEETHAALASLKGDDETFDELLTRLLRERRENVRSGAGLWEGTDAAERARAKRREMKRGVDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY6</accession>
    <name>V6DVY6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">C472_16084</name>
        <name evidence="13" type="ORF">BN903_222</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077082.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74143at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO" evidence="12">
        <location>
            <begin position="65"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CDK39448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="304" mass="34857" checksum="ABA350C45C3381DF" modified="2014-02-19" version="1">MVRNVAGDMAELDPEDFYLLSGVEQGMRFSEWVRRDKLPDYADLTREEVDYRIDRCLDRELIERKTIQYEGYQLTFEGYDALALRTFAERETIDGVGSPLGLGKEGDVYEAQSFRPLALKYHREGYTNFREVNRDREYTADRDHVSWLYTARKAAEREYEAMEELYPDVSVPRPVDHNRHAIVMEKFAGVELSRASLDPEQAVGVLDLILRELATAHDLGWVHADASEHNVAVAESGVTIFDWPQAVSVDHENAREFLERDVENLLRYFARKYPHEVPRDADTDGIAAAIADGSFETVRAFGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY7</accession>
    <name>V6DVY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5218" checksum="8E01680ECF606E79" modified="2014-02-19" version="1">MYRAFDHSPAHTYEIATALDYHGVCDVDDSRSSAAFRDRLRSKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY8</accession>
    <name>V6DVY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5358" checksum="22B74862491FCFE2" modified="2014-02-19" version="1">MSAWHTSHTTRSGTMNVVMIDREGPSGRRLLLIFSQRSGSGLNVFRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVY9</accession>
    <name>V6DVY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5339" checksum="EA751D2DAFF9C0B8" modified="2014-02-19" version="1">MVEATVATLKAVSSGGRVGSDGGFTPGRTAALLRIGRRSHARSITSRSPGSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW70</accession>
    <name>V6DW70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_07436</name>
        <name evidence="1" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6089" checksum="96B02EAAB54AF83F" modified="2014-02-19" version="1">MKQSDVVEELGWSKSKTSRVLSRMADAGGVEKLRIGRENVIDLADGDDAADEDRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW72</accession>
    <name>V6DW72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7368" checksum="0B463792845C3BF2" modified="2014-02-19" version="1">MTDRFTPRGAHGRHMPSRDGLLGVQTSIIGLAILELFGEVSGGFLVGIAVLLYGSYLVGRNRKGPAVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW73</accession>
    <name>V6DW73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4291" checksum="59DBAAAB996994A0" modified="2014-02-19" version="1">MSARLRGLRSDCDTVSLLVLRHAPRGRAAVVWLLLGTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW74</accession>
    <name>V6DW74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C470_07546</name>
        <name evidence="5" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="66"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="118"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="193"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="256"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="464" mass="51240" checksum="7FA90C9BD63B6ED2" modified="2014-02-19" version="1">MLETMPAAAFLKDTDGRYLLMNQACRDLLDIDGDPVGMTDEELFPRAVAERARADDLRVIEGGEMVEIEETVPTPAGETSRLTRKSPVYDEEGEIRAICGVSTDITEQKRREEEIETTREELRQIIDLVPDLVFAKDRDGRYLLANEATAAAYGKTPEAVEGNSESDIIPSVDDSEAFRQDDIEVIESGEPKTVGEETLTTAAGETRVFQTTKIPYRNPKTGEDAVLGYARDVTDLKAYEETLERQRDSLTLLNQVVRHDIRNQLMVAESYTELLEDALPDDQSRTYARTVIEATRQAMEITETARDVTEVLLQVGSDRSPVSLRDELSEQIAQIRSEQDRATVSVDGSITDVTVLADELLEAVFRNLLMNAVVHNDKDVAEIGVSTRVSGDMVCVSIGDNGPGIDDEHKEQIFQEGEKGLESGGTGVGLYLVKTLVDKYGGDVWVEDNEPTGSVFVVELPLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW76</accession>
    <name>V6DW76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6432" checksum="DEF8A346EF197008" modified="2014-02-19" version="1">MRRGGVRYLPTLVNARLLASNLGNDTSNFRLGWSHHHRGATARLAHGGQARARTNVTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW77</accession>
    <name>V6DW77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03274</name>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8247" checksum="ACD04AB9AD54B07C" modified="2014-02-19" version="1">MVGRYGDIDYSRATKRTFGVGAVLFAFGLVGDLYLRSTGAPVPEWEQTLLVDAELLGVLVMLLAPFVFGIVLPLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW78</accession>
    <name>V6DW78_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative HTH-type transcriptional regulatory protein BN903_49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_08716</name>
        <name evidence="4" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077985.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76134at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00584">
        <property type="entry name" value="HTH_type_cro_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020886">
        <property type="entry name" value="Arc_TR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="323" mass="35176" checksum="451BE4497DA9CC68" modified="2014-02-19" version="1">MSRTALIGNVTAMLEDAGFLVSDRCAVRPKSFDVAARRDEDLLLLKILGNVDALDAETGAEMRRLGEYLRGTPMVIGVRTRDEELKPGVVYFRHGVPVINPDTAYDLFVEGMPPLIYAAPGGLYVSLDGDLLADEREERGWSLGRLATELGVSRRTVSKYEDGMNASIEVAIQLEELFDQPFSSPVDVLEGADDVRDAEPTPSAPAADPDDEHVLHVLTSAGFTVHPTARAPFKAVSEDEDSPATRVLTGHSAFTAAAEKRARIMSSIGEVAQTRSVYFTEEDEKRESVDGTALVSCEELADVTDPEEIRELIRDRARAPSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW79</accession>
    <name>V6DW79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphonate ABC transporter, ATP-binding protein</fullName>
            <ecNumber evidence="8">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">phnC</name>
        <name evidence="8" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078005.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72957at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03256">
        <property type="entry name" value="ABC_PhnC_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012693">
        <property type="entry name" value="ABC_transpr_PhnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02315">
        <property type="entry name" value="ABC_phnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="275" mass="29543" checksum="0BD369F13C8D62E8" modified="2014-02-19" version="1">MSSITVDGLTKRFGETVALDDVSFEIPEGEFVIVLGVSGSGKSTLLRCMNGLETPTEGEIRIGDTPVTEPRPDIAMIFQQHNIIEQMNAYSNALTGSLNRNTFVDSLFQRQSEADKLQALDALDTVGLLDEAQQNAQQMSGGQQQRVGIARALVQDPTLLLADEPVASLDPGSSQQVMGYLRTAAAERGLTAVISLHQVNLARKFGERFIGLRDGQKVFDGYRDEFDMDVIDQIYGDIDTEGMFAPDGETDGGSADDGSIDDASSKRVSGGGMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW80</accession>
    <name>V6DW80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4750" checksum="8ADB8CB39C27EC51" modified="2014-02-19" version="1">MKISTPKYFIRSNRYYFNYFLWDCSDNADPAHRTETAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW81</accession>
    <name>V6DW81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4580" checksum="0FBE021D9BB37F28" modified="2014-02-19" version="1">MALQCDPPHLGDIGDDEPEEEPDPDRIYEKEIERQLKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW82</accession>
    <name>V6DW82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5504" checksum="A1AA9E0CF180564B" modified="2014-02-19" version="1">MLLGRIAAEQARATALKFSRSITTSPILSDWGNNAIAPEGFQQIRPRPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW84</accession>
    <name>V6DW84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3801" checksum="22FC7D8A075F1803" modified="2014-02-19" version="1">MSLTDSSPSSTADSASSVSTQLPYGTLCCIGLKICYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW85</accession>
    <name>V6DW85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9279" checksum="6ADEAE634894F04A" modified="2014-02-19" version="1">MGSAATAGVDRDVLGGDLNSRATQPLCSAIFLASLGKCTGRDLNSESDVLARGSRLHRSLRATDSVQITLGDFSHYVREMYRPRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW86</accession>
    <name>V6DW86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phage integrase/site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C481_11170</name>
        <name evidence="6" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="7"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="116"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="332" mass="38233" checksum="031735E8717C9096" modified="2014-02-19" version="1">MSELEPLEPEKAVELYLKHRSDELAESSLNAHRLRLKHFVRWCREENIHNVNELTGRRLHEYRLWRKDDGGLNRVSVRTQMSTLRALMIFLEQIDAVQVGLNDSVDIPTLDADEGVRSVHIDNEQAQRILSHLEKYEYASLRHVLVLLLWRTAIRTGTARGIDVSDVDLDDGFIEIRHQPSSSTPLKNKRDGERYLNISEKTSSILADWINKRHPETEDDHGRTPLLATNYGRISKGNLRKQVYWATAPQFVGDDCSCDADEHGYDLIHECDDAVSPHALRRGSITMHLREEVPKPVVSERANVSSEVLDAHYNETSLKEQMELRKKHLDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW87</accession>
    <name>V6DW87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8103" checksum="CEF34BB646392AB0" modified="2014-02-19" version="1">MWGLCRRITAVDTAIRLERLCREASAIILSLPWLGPRVGVTKSLLRLTEIRQSNLLANSSPRLFEQEAEKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW88</accession>
    <name>V6DW88_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">secD</name>
        <name evidence="10" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Part of the protein translocation apparatus. Forms a complex with SecF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_A">
        <property type="entry name" value="SecD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024912">
        <property type="entry name" value="SecD_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="442" mass="46985" checksum="291CD34F16D56509" modified="2014-02-19" version="1">MAAELDNASARNVGAVPGERAVEVTEPSVTEDQFRRAMDASGYEYADVRSGVTQETRDETMNVIQGKINEAGLSGGSVQQVQSITGEYFILVEVPGEGRQDVVDLLEERGTVRIDIAYADGNETAVDEGVLVQENFDEIGTATQSDQGTGSYVPVTVRSTDESGQSPANNFQDAVVERGFPDAYNTRADRCEYVNGSLTGERNPCLLLVVNDEVVNSFGMDSGLADSMGAGSWAETGRFRLTTGEFSEAQTISLNLRAGALPADLDISGEGTSSSISASQGENFRTYSLVIGILSVFAVAGMVFLRYREPRVALPMIVTALAEVYALLGFAALLGYPLELAVIAGFIAVVGTGVDDLVIIADQVMSEGDVSSRTVFDSRFRQAFWVIGAAAATTIIAMSPLMVLSLGDLSGFAIFTILGVLVGVLVTRPAYGDILRRLLTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW89</accession>
    <name>V6DW89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7696" checksum="F271DE56324F9EDE" modified="2014-02-19" version="1">MFSVDMYATTQSQLADDRAAARSTGVLLPYRAQNQVAVGSLIQRFRAGSQHSPFAVMLFLSHFFINSSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW90</accession>
    <name>V6DW90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6019" checksum="3B559B489258B1BD" modified="2014-02-19" version="1">MSSDTNTAGSCPVCEQEYKGEEDVTDNKTVPLPDANHICFLDGKVYIHMENQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW91</accession>
    <name>V6DW91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08781</name>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8317" checksum="D253E7510F30A0A5" modified="2014-02-19" version="1">MVPHGIFEIPALVVSGALGVHLGVVSWRTFRGRASRERFADALETAFWVTVGLGILLGVAGIVEGFVSPYYWRPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW92</accession>
    <name>V6DW92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_00751</name>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13543" checksum="89FAD1578ADC9C77" modified="2014-02-19" version="1">MTDDPASFAIPMDPDSAFNAISNSRRRRVLLSLSQSHRTIPAGNLAVEIAAIENAVDPSKIGSDKRTSVYISLTQSHLETLDECGAVEFDDRSKTVSPTDATEPLAEYIRRLQTACYKPDSEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW93</accession>
    <name>V6DW93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4676" checksum="CC398E509D530D2B" modified="2014-02-19" version="1">MLIRTNQSIFPLRNLKFLNIDNTVLLLVYQDGLTVPSATGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW94</accession>
    <name>V6DW94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="3912" checksum="C8A49251307DBC97" modified="2014-02-19" version="1">MSEALVLPAVIGLMALSTIHVGVAAFLTAFLAVVVLASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW95</accession>
    <name>V6DW95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6854" checksum="3CDB8EC93466828C" modified="2014-02-19" version="1">MNVITVPRNATYNTTRRFHVSIEPRYAAAVQKREDSWDPVPPVCQPSGDRIVLASIESSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW98</accession>
    <name>V6DW98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4456" checksum="55DB708878DAACE9" modified="2014-02-19" version="1">MLLISLLLLTLGWPVRTTLFYRPISDLFKYDSVRLTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW99</accession>
    <name>V6DW99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_08640</name>
        <name evidence="4" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077632.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102179at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="32"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="182" mass="20521" checksum="7A2B6190849D6BB1" modified="2014-02-19" version="1">MSTQKQARQRYGDVHESEALRVPEEKAEQLVDALNSDLAATYVLYHQIKKHHWLVEGAEFLGIHEYLGEVAADLEEGADVLAERAQALGGVPLSGGANYEEHAPVTPEDADAYDIRTSLEHDLEIFGDITEQLREHIQLANNLGDYNTEEQLREILETVEEHGHHIEHYLEDDTLVTSETLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ2</accession>
    <name>V6DRJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4286" checksum="B0894AB6D2A5541D" modified="2014-02-19" version="1">MGNETDLGCHIDPSFFTEITKSSLLNLGNHRAINYYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ3</accession>
    <name>V6DRJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5164" checksum="BF6F30F59D9B440C" modified="2014-02-19" version="1">MRPRAATERIISIDSGSGSRTLLGWLFINQILVLLSAIYKQSTCPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ4</accession>
    <name>V6DRJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3867" checksum="D5B4330D3BA9BFCA" modified="2014-02-19" version="1">MGCPSASPDIGGTLGLPIIKLALAVRCEAIQAHDFSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ6</accession>
    <name>V6DRJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter</fullName>
            <ecNumber evidence="2">3.6.3.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01111</name>
        <name evidence="2" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.19" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="19"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9470" checksum="8E9B484BBEC08E11" modified="2014-02-19" version="1">MRSVSKYFDGGDTVANYKLDMEVDDGEFVVFLGPSGCGKTTALRMIAGLEDPSDGEIYFDDDRVDGMPPADRNVAMVFQNYALYPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ7</accession>
    <name>V6DRJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Family 1 extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_07142</name>
        <name evidence="2" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076756.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="33798at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="408" mass="43734" checksum="E88A5BF5DA945793" modified="2014-02-19" version="1">MLGSVALAGCSGGGSDGGDGGDGGDGGASSLEITGVWSGGEQESFSKVMDFVEESTGMSLEYFPRDTDSLLTGTLMDYESGVASADIVVMPSPARIISDAQNGHLAPVGDAWDPENFAVDPSRVTVDGEVYAAPFKMDLKPGFWYRKSFFDEHGLSEPESYDEFLTLLDEIAAIDGVDAPIASGNGTGWPLSDLTEGFLMRQDDGASLQQGLIDGDASFTDDRVATAFDEIKALHEEGYFSQTRDFGVQYEYFWDNSLPLYFMGSFTPAQDAVQDPSDLGVFRLPGVDGISSSVNWFTVPTYSDNVDAAREALSSFVSAEGQQVWVEDGGFIASNTEVPDDAYEIEVMANLPDLAAEVTVVPDLDDALGNPFQQEFWSVLKGLWATPDTATEEITSALDDAHQETLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ8</accession>
    <name>V6DRJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C479_09298</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045713">
        <property type="entry name" value="DUF6069"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19545">
        <property type="entry name" value="DUF6069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12653" checksum="F5716144D1E89887" modified="2014-02-19" version="1">MALAIALIVNLVLGWVALTQNLVASTEFFQYPPIVVWTLLGMVGATVVYRVLTQRSTAPDRIFVRIAAIVLVLSFIPDLGLALFTDSVTLSEAIGLMSLHVPPAIVTVLALPETPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRJ9</accession>
    <name>V6DRJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_11730</name>
        <name evidence="1" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076553.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107386at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="13455" checksum="FC0CA06FD44D20D6" modified="2014-02-19" version="1">MSPISEAVLAFDGPTPRVVADLRSVSFEVEHVREDVEGVYSDRDLDEAYQLVMSNQITGDDFKELIGESRYNAQTLFFDDVIVFLFPADRYDAIFASFDYDGAFPVNELVDAVAEARATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK2</accession>
    <name>V6DRK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5374" checksum="9C4CAE0682EF3987" modified="2014-02-19" version="1">MPSKPLSEINNVLHKSDLLLALGFGVGVGIVSGAYPAWKAANERPVEALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK5</accession>
    <name>V6DRK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7546" checksum="2CFA063612593A8B" modified="2014-02-19" version="1">MYSVMARSTRRPGKKGSPRSRRRRGDGRRETHANDGDPPVPVFYKRRVKTRSSMLSVPSVAQIPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK6</accession>
    <name>V6DRK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_01146</name>
        <name evidence="6" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076582.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63271at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="97"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="306" mass="33343" checksum="87279A81C2D72832" modified="2014-02-19" version="1">MSTETPQSSDVERNVVERLRASPFLQELLSNRIAVFGLLIIGTMFAVAIYARLTYELDAIVDTMFNANPTQAAPSTEFWFGTDGQARDIFPRVLYGAWYALKFGTATVLASTVLGIAAGVVAAYYGDLTDNVIMRTMDVLLSFPSLLLALALVTIFPESLGLWRAVAALTLVYTPRFARVVRGAALKVLEDEYIDATYALGATDPRLLIRHVLPNCLAPITVQSTLNYGLAIIDIAALSFLGFGASPGDPSWGMMLSEGVERGLFSGAWWWSFFSGLFLALTVLGFNLLGDGMRDALDPRMRDTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK7</accession>
    <name>V6DRK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Concanavalin A-like lectin/glucanases family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Plut_0367</name>
        <name evidence="2" type="ORF">BN903_360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076013.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81213at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="271" mass="29562" checksum="DC91C49B35ECD9B7" modified="2014-02-19" version="1">MTNTPHITSDRRAPRDNSTSWGGESGWEGEVVDAQYVTVANGTITADRIRGPTEGLVAHWKFEDPTTPDAIDTVGTNDGAIDGATYAGAGRVGANSLLVDPGSRGSVTFTSSELDIQGSFTIAAYARMDGSALEGWQRIYQKGRGKDDRTVELYVADNNNKSTGLTGFRVNEETPSKATRIHHERPGFSFGTYYHYTAVYDAVNEYLRVYIDGTLLDSVTHTDGIDSNTRHTIGNWATNGSRPWNGGIDDVRIYNRALPRADVESLYSAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK8</accession>
    <name>V6DRK8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HAH_5058</name>
        <name evidence="1" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5795" checksum="F3C2E22BBFD4AB75" modified="2014-02-19" version="1">MYQPTDPEQVADEMQRMLNDWYAKMGQLIQEFENKYNDTDPSEPNTAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK9</accession>
    <name>V6DRK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10713" checksum="B6FAF4A2CA8B31FF" modified="2014-02-19" version="1">MPGDLSTLGERTATVRGMWQDCRLPLRPTHSLRSLLEAGGSASNTLTPGRTETRTEAPTEPRPKPDPYPNLRPNPTEFDLSRRTPSGGPKRFVRVTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL0</accession>
    <name>V6DRL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_14932</name>
        <name evidence="1" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109970at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11773" checksum="38A578F5696D4157" modified="2014-02-19" version="1">MSENDPADLLPNDRVKQAALDGEVTQLHRGNRYGDEGDTFEIDGVAFELTEVTERTLGDMTDADAKREGSPSLSAYKERMVKAHGGSFDWDDDADVVRHRFERVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL1</accession>
    <name>V6DRL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9307" checksum="3B284E847197396D" modified="2014-02-19" version="1">MGVVAGHHAGPAGRTLRGRTEAVRHPGTVGRDPIDVWRVDVGPVTAEVLPEVVTVNQHYVRTTRRVGGRVGFDRHVPINRRDANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL3</accession>
    <name>V6DRL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6223" checksum="3708F1748DFBC4F1" modified="2014-02-19" version="1">MNEGLYTGAADAYSTGRRRATQPVVSRSREAVAFQRPRRSGGRSTLASRWLAGERPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL4</accession>
    <name>V6DRL4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulf_transp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C464_00774</name>
        <name evidence="8" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075793.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108031at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="7">
        <location>
            <begin position="20"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="18783" checksum="7E35BFCCA4BD67D6" modified="2014-02-19" version="1">MATSLVLLQSVAELFPNGISRYAVGGLLVGLGTVVIYVGTGIPAGASTFLESTLSYVSGQSRFQQYVASRDWRVVFTAGIILGALAFAATVQSGVVTTSLYEPGTTGQLYEVAGVTLWSTDVQPWRLFFGGILVGIGTRVGKGCTSGHGVCGVGSASKTSLVGVATFLTVAIGTAQVVAALGVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL5</accession>
    <name>V6DRL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076017.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8799" checksum="E40226045E438545" modified="2014-02-19" version="1">MKFVARDGSTVQRFLLVRSAGATSSGYKLYGYDPEENARNFLEDFGIDVHPNHHAEIQAAKRKIRFYAGPNADISTHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL6</accession>
    <name>V6DRL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="403" mass="45260" checksum="462CDE2F2912E695" modified="2014-02-19" version="1">MRVVLVELDRSARPGHGPVYQPQPEALRVFERGLLGVVEGLSLDLRDPAPRVLDDERRRVAVAPHAHRDRHVVVVVFDRVPKRLLERERERRMRSDDTAVGEFRVNRGFGRLRGQLGHARLDDGDEVDRLERFRPPDRGDAPRSFARLDELLQVGPGDPRPLRDRRPVGRVLDPVEVAERDRQLVADVVAKHAVVDREKGRQLLGLRELFVGLHHVQSRPRADRRTEAGRERDQKGELERVVIEHPDEPDDTGERSEGEGGQAADPDRPPPPGGGDVPLGQVVHGVEDDAGETEDERRFEEHASASLADRHVSHAETGADSAERDEAVAGRDGASHRESYSPLTFMGFLTDRPHRPGYSSYIISTSSANRSKMFRRFFFIVGVRRSFASVNSSSTSRNRLICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL7</accession>
    <name>V6DRL7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01031</name>
        <name evidence="2" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076564.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109158at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="3"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="128" mass="13767" checksum="3DBB6A84D6EE4DD6" modified="2014-02-19" version="1">MTLETLAPADDLDADAFDEAVLDALTADDYVFKVWGGDWCGDCQRQLPAFGAALAAAGVPDDRIEAFPVVKGPNGKEGEFVDEYDIELIPTVVVEDADGEELARFVEEEDVSIAKFLARQLADVEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRL8</accession>
    <name>V6DRL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_01393</name>
        <name evidence="2" type="ORF">BN903_146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009845">
        <property type="entry name" value="DUF1405"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07187">
        <property type="entry name" value="DUF1405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="232" mass="24717" checksum="CB62F98C9D598DA3" modified="2014-02-19" version="1">MPRSEQFPRLRRLRNPAVRRRVRAAIAEELLGTPRSLAVVCAFTGFMLAVGVWYYVPTANEVPVPFWPLYADSAVAVALGGAVLAGIAPTVRRGGDIGVDIPVSRASAYLQTVAFVWLVQFGVWPLVSLNLAFGEYVAAPDAWIYYWGVIGTHLLFVGLALLFPAFGRTTPGALATALALGVVNVVVDYWVGYHPPLLYEPGPGLAAATLAIAVGAVALASHSFRRLGEGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM0</accession>
    <name>V6DRM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5761" checksum="AC6D9AC4C685CB59" modified="2014-02-19" version="1">MFAAGVLAALGVAVTQVVQLTLIESKVVNTGIEGLFVGMVVYLDLKTLELSVNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM1</accession>
    <name>V6DRM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Initiation factor 2B-like protein</fullName>
            <ecNumber evidence="2">5.3.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01256</name>
        <name evidence="2" type="ORF">BN903_138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076595.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54988at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="30602" checksum="9622CC075583E682" modified="2014-02-19" version="1">MIDETVAEIRAMRTHSTSAVAVKATRSLADLLDREYVAVDEFERDLEHNAGVLRRSNPSHAALHNAMREVERSIVGEATSVEGAKQLLEDVIARVVDDIETAKGEAAANAAEHIEDGDTLLVHDYSTTVLEAIENAARDGAHLTVYVTEARPRTLGRKTARVLAGMSRVETRMVVDSAMGYALRDCDRVLLGITCITGGTYYNRIGTFPLVVTARELGVPVTAVGSGAKTIEEFRFENEFRDAVEVMREPVEDVEIENPSYDATPIGMIDTVITDDGVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM2</accession>
    <name>V6DRM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyribonuclease/rho motif-related TRAM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_07027</name>
        <name evidence="3" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076570.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110514at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="16585" checksum="53E3CF9A75992A70" modified="2014-02-19" version="1">MVELTDSLRVLYTGSIEEQDGEYVVRVPESEIEHGTVDVGESYRIALISREESGDNGSSTGHEAVTDSPAVDESPSDDGQRPTSRGAAGAVQPDPPVSEGEVRDVTIETLGDKGDGIAKIERGYVVIVPDAEPGEEPTVEITSVRENVSFANVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM3</accession>
    <name>V6DRM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ZOD2009_18814</name>
        <name evidence="2" type="ORF">BN903_375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="18155" checksum="EEC63DCAE154EE1B" modified="2014-02-19" version="1">MPPFTPLPIREHLDLDFYPDGRYTLHPEVRFFVAGGEVLYHFPRVGKETFARATDGVAHYERVINAIDDNIDQLYEWASRAAQEFDDASWSLDFVMDTDDNWFATDMALNTLYYSSEKNRWHNLSEHDTGSPYNLEEQVGDTFPEPEIPNDGGESTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM4</accession>
    <name>V6DRM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="16422" checksum="9874EDC6172D5B8E" modified="2014-02-19" version="1">MELQKGDVLLVKRTGGRSSKPANPAGQVYSDRNIPLFGGTNPAYHRGNEGDVICVELIPASGTLKGKWKNTTEPFDSIFKKWKKKLTYRDSDLDYTIALDQVPDDYKFPDEYTQEQTENNARETEERDEWNERSSELMSDLGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM5</accession>
    <name>V6DRM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halar_0123</name>
        <name evidence="2" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="8278" checksum="F30D1C7EA39B9C57" modified="2014-02-19" version="1">MNGQVDYTDRNLIEKWIHTLKMRIDRFHHSWVGSRASVREWLEQFVRYYNHQRPHQSLNNRTPAEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM6</accession>
    <name>V6DRM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="320" mass="35634" checksum="32BE1C455F9F98F5" modified="2014-02-19" version="1">MRDRQRRRRDLAVDDRPAVGPDRVRHVAVVHQAPDRVRKADATVAVPLGAHPVPRRGRRDAERRARFVRYRRVDVEVVRALEHPGIDRLVEEELGRAGRVGEVVGLELAFPPVVAAGHVHRGRDRRDAEERRLDRRGDGSRPPERVRPEVRALVTAGDDRVRVGDEFAEARDDAVDGSPADHVAQVVLVDGDVVGEEAADRGLVVGRGDHGHRVLLRKRVVERSESGGVDAVVVGQQDPVDAHTRFTGESGKSPPSTGGGCREARAVPYRTERHTYRRAERPVWDSGTPPRRSRRSPTARNGPTRRSANSATRSTRRRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM7</accession>
    <name>V6DRM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_04022</name>
        <name evidence="1" type="ORF">BN903_143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076599.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116208at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="12896" checksum="BABF14E0E6C64E87" modified="2014-02-19" version="1">MERRRLLAASATVVAGGVAGCLGSDDPGRLDLTVRNDGDGPVDVDVVVEGDDGTTYEEESDRVDAGVARAFEVVVGATGRHEVAVTGPDWEGRLAWDAGTCQLYDATMVVGGGTVEVAGECVNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRM8</accession>
    <name>V6DRM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11454</name>
        <name evidence="1" type="ORF">BN903_151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="291" mass="31112" checksum="794653F6F9FCA015" modified="2014-02-19" version="1">MLLLNTVIYTENLATRGADAGGAEAIEFRDDTVDDLAGILHREHRNRSSDDVLNDFDESVKTYSHTVAGLRARDGVIANVSVNRSTVERGYFVAQNETESGFRDMTAPDGTTANWTVVSGVGRTRNYRLTVNSASVSDGEDGAFAVVADGAGENWSVTLSNDSADAIDVRVRNATVNTTRTFSHEGDGNVTIDLTAGTVGGQHFPELVWAGGVQNGSDPSDTYDIRHENGGNATGTYSFVVDERAGTSPLDASSRPYVTDAVYGVDVELTHRTPELTYGDVIRLAPGERDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS00</accession>
    <name>V6DS00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04538</name>
        <name evidence="2" type="ORF">BN903_266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076702.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="120474at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9853" checksum="87A27404F0DFF1EA" modified="2014-02-19" version="1">MTDTESASANGVAARYEETDGERRLTFSLDGREATVAQNVEGYAMLKVRPGPDGDELERYYGFDMALDHAAELLGVAVPDLPVPDAAADMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR0</accession>
    <name>V6DVR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9680" checksum="650E1B5D31A6972F" modified="2014-02-19" version="1">MRESLAVLGVDDRLEVMSAYPRNSDVYNEDRDTHSRMAIPSVCPECENPVDVVSIPPNKNDSQGWQTAIECDTCDDRMFTRELDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR1</accession>
    <name>V6DVR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_09932</name>
        <name evidence="2" type="ORF">BN903_132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334935.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116612at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="276" mass="28652" checksum="A74EED30A5F88FEC" modified="2014-02-19" version="1">MAPAITHFLVGASLCLLAAVPFIIRSDTDPLVITWLIPIGGIWGILPDVHHVAPVFATELYAIHGSPWVSLCAFHYPLDTLAVRHRAHASIFLAIAGFVGVLAVITLVARERPWQSIADTRRERMAIVGGASVLAAGYATLALTAVVSVQWAFGTVASLVGTDRVAIGGLVVLAAGFLAGLVYAVGFVTVMPRHARSTPGVAGVIGAGIGVIVWVGTVLVGLPLWTRWVLDDALSIPFVRPVALGGLVVHGVVFGVTYALVYGAFDAAGTGQLTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR2</accession>
    <name>V6DVR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C461_06289</name>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6489" checksum="52C359CF14CCF460" modified="2014-02-19" version="1">MKSTRKGLRDGDLFKDTYERLTCADCEQVLKTKNDPDNVFDIRTCPDCSTQYKDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR3</accession>
    <name>V6DVR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6209" checksum="BCB7F3BF2A1D195B" modified="2014-02-19" version="1">MTGSDPVSLPYHVECSSDGLALTSNDMGSMAHTPYRVKTGPIKLDEANSSTPTPTPDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR4</accession>
    <name>V6DVR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase (ISH3)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_04189</name>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="283" mass="32890" checksum="B1F0FC767FB91335" modified="2014-02-19" version="1">MEVCADLHLRPYYGDKDDTDGLYHSVAKRRTTAFHAYATLYARVENKRYTLAVRRLRDGDTASSVLAEFFGVLDGLDTVVKAVYLDRGFYDSKCLTLLQAHDYAYVIPIIRWGETIQQELSEGWSRVIQHDLTGKLDSPAVTVEFPVYIDCTYLNGKYDENGVARHGYAADAPFIDSPRDARYHYSKRFGIESSYRLSEQAIATTTTRDPTIRLLYVVVSLLLQNVWRYLHYEYVATPRRGGRRLWWWPYKEFINMIRRAAWTALAVRRAVPANRPPDDRFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR5</accession>
    <name>V6DVR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HQ_3661A</name>
        <name evidence="3" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="523" mass="56528" checksum="8D29516A06107FB2" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR6</accession>
    <name>V6DVR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6730" checksum="4D39EE7FEA562AD8" modified="2014-02-19" version="1">MDRSDTVLCWLFNSLSRSNGIADRRPKLVDRCGSDTRGHRTVVVPFCSVTDDSRSEMAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR7</accession>
    <name>V6DVR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transposase for insertion sequence element ISH11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">OE_6107R</name>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="235" mass="27170" checksum="7A3000B31B2F283A" modified="2014-02-19" version="1">METETLALFEHLSFEFLEEFDVFVPAETGRTRDHEPPELMRGFLHCYYKDIYGIRPVERELRNTVVWLSCGFDRPPLRDAVDRFLTNLEHVVNEVFDRLVEQAAARGLPDLTYCIDSTDVRAMPADQDASKCYDPTEDEYYYGCTIVSTAQKIPIAAEFTESKQAPEETAMRVTCDALVVKHPIWMVGDIAYDTLDIEYRSKTASRNTAKTFTRSNRCWTRRTIAVRELNELTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR8</accession>
    <name>V6DVR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06818</name>
        <name evidence="2" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077774.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42378at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="408" mass="45224" checksum="B558EAC25A3ED71C" modified="2014-02-19" version="1">MQRTRRNLLTASATVCLTGCLDVDGVTYPDEPVPNESDPDRGMPPDDDQAGDPTNDNLGPHPDLAAATRSVVDDTIWFAVSYPSAIDTYREATADVLTIIESVRKSIDGQTDPTAAMAKRLEAAGYDAAERSAAALEPHFEPAGLIRAQTDNHVPELIRFARRNDADRFVEELERMHLSFFQIRTPIYIGRRFSRNPIHNRLLERLAPGGPDKVLAELAAPGYRQFSTLAYQPYSDESGMYPPTFTDEALPQEQRETLRERLGPVIQTDDRTAELFVTVASRPEPASRRGVAFRGAPGDLDGVPVYVQRYSSAGRANERLSAILNAGDTEGREPIVPETNASDDATAWHRYYHREAGSTRKDLDEFPGVQYGYLLQAGEFLLATGFSGDAWEERPQWQGQLVDTWVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVR9</accession>
    <name>V6DVR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="9034" checksum="D98B3735FA39500F" modified="2014-02-19" version="1">MTGVYRRNAPTDPRRHNERPADALDDQPVENRLAENSPGEDHRHFEQRPTPTTDTKTPHRDRSYTENERRPASTRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS1</accession>
    <name>V6DVS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1341-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_13865</name>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="145" mass="15808" checksum="26F97E12853CFBDF" modified="2014-02-19" version="1">MSDDLDALGFAASKLWNVGRWTCIRIWDEIGHIPNHAELTRTSRITNAMMTYILSQVSESFKNSLKRSVGGTANDATEIRERTRPATANTTTNTHEVRSRSKPPASNSIPSTIASDSQKARTSRSIGPTSSSMNSTLDPTLTSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS2</accession>
    <name>V6DVS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4796" checksum="8AFE3FA3AF56C7C2" modified="2014-02-19" version="1">MAELSQSLKSSRINIGTKISSYIDEGLDEIIQAISKYHDIPQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS3</accession>
    <name>V6DVS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LtrC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_17348</name>
        <name evidence="1" type="ORF">BN903_152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="316" mass="34883" checksum="F38178B53A9697E7" modified="2014-02-19" version="1">MGGSMAESHSSGRVTFGDTDARADQMHQAIDQWLAELVEAVDTARASEQFQQWLDIQRRFHEYSHRNTLLIALQCPEATKVAGYRTWQDEFDRHVTDGESAIWIWAPIITNQCPECGDGPTYHERNDCDYDETPPDEWDEGVVGFKPVPVFDVSQTEGEPLPELDTAARGDPDGLVTALLEAAATLELSVEIVDSDAWSYGDADGVCRHVDGDPHIQVRGDDTAAVAGTLLHEYAHALLHDPADTAGREAREREAEAVAYVIGRHFDLEMDGSAQYLAAWHDDDSDQLFERCERIRETSTTLIETIAAQGGSPADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS9</accession>
    <name>V6DVS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenite oxidase, large subunit</fullName>
            <ecNumber evidence="5">1.20.9.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C468_01910</name>
        <name evidence="5" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.20.9.1" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077806.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1029at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050611">
        <property type="term" value="F:arsenate reductase (azurin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041632">
        <property type="entry name" value="AioA_3Fe-4S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014066">
        <property type="entry name" value="Arsenite_oxidase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18465">
        <property type="entry name" value="Rieske_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02693">
        <property type="entry name" value="arsenite_ox_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske_3" evidence="4">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="2">
        <location>
            <begin position="119"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="3">
        <location>
            <begin position="711"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="859" mass="95981" checksum="6C12B0F04AD7C130" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT0</accession>
    <name>V6DVT0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_12838</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="81"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="212" mass="24949" checksum="9E2024E0B3FEBFCF" modified="2014-02-19" version="1">MAEFDRLSERITWIDLSFVERDRTPRWAIEVGIRCHLAGMSLREVSKHLELFGIRRSHVAVHNWVHKADLQPISTISEDQLAVDEKMIRLHGQKFWLYGAVDPQTNEILHVSLYPTANKQTTRWFLTELHQRYQLDGVEFLVDDADYLGPVLAEDGYRFRVIRHGNRNAIERVFWEIERRTSSFANSFSHVALETTQNWLEAFAVYHNSRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT1</accession>
    <name>V6DVT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11129" checksum="338245A181CE502B" modified="2014-02-19" version="1">MRSSQPGSTTCSETRCGCRTAGTFSGPFSDTDSLADVLVVQNTGLLPVLVILRRALILEQLFIYYGTANNRSRLGQESRRRYEHRPNVERGEQAPARRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT2</accession>
    <name>V6DVT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1921</name>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077780.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84281at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019278">
        <property type="entry name" value="DICT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016954">
        <property type="entry name" value="Uncharacterised_Vng0742h"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10069">
        <property type="entry name" value="DICT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030471">
        <property type="entry name" value="STR_Vng0742h_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DICT" evidence="1">
        <location>
            <begin position="131"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="262" mass="29200" checksum="CAEBF82E910F9978" modified="2014-02-19" version="1">MVDSIRDFFAEIENPDRNLVVLDQSSPEPVRNMLNSLVEDQLVSLTQLDAEDTDSIRGEADTRVVALVENGNVLARSSVNELLESVLLINSDLYKTGAIDLGDVVLPDVLKGLDEVPFRVRGYPESHNEKLLLIVISRVIERIASETGGGTLRASFQRLSRLYDEKGTYEVYDTLSKQDVDIHIYGVCDIEPSKTPPVTVHTGDTYVYKNSWFVVFTPPAGSATSDYAALVALEAEPNVWNGFWTFRPELVTQIETYLTENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT3</accession>
    <name>V6DVT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_2972</name>
        <name evidence="1" type="ORF">BN903_157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077043.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="133826at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="21222" checksum="B6DD5115ED7AE22D" modified="2014-02-19" version="1">MSTRCQLRFVRTLDAGRTADPTDPVAQVYTHSDGYPSGVLGRLRELKQLLEATSSVRGPSYAAAQYVFLEKLASLPLYLDPDREAGQRLDAHSPADVCQPSRMQHLSQPLFLLGHGIEDPSSGIHGDEEYLYIVAIPSYDLGQVEPPTWEVAVSKQCGFPRWDAQTDDAFSEATWQFEGSLTAARGEFCDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT4</accession>
    <name>V6DVT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Family 5 extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02012</name>
        <name evidence="3" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077812.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6658at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="96"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="543" mass="60558" checksum="46C05160DD8DE785" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT5</accession>
    <name>V6DVT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase (ISH8)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C487_01615</name>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077782.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42375at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="105"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="424" mass="49466" checksum="596ECADBE24D2917" modified="2014-02-19" version="1">MRRLTTLFPSKFLEEHAEELGVVERDRKLQIPAFVWTFVFGFAAGESRTLAGFRRCYNSTADETISPSGFYQRLTPMLAEYLRDLVERGLDEVAVPNAVDADINRFRDVMIADGTVLRLHEFLSDQFEARHEEQAGAKLHLLHNATEQTIERLDTANEKTHDSTLFKTGPWLENRLVLFDLAYFKYRRFALIDENDGYFVSRLKQNANPVITAELREWRSRAIRLEGKQLRAVLDDLDRKYIDVEVEVEFKRGPYNGTRSLDTKRFRVVGVRDEDADDYHLYVTNLARKEFFPADLAEIYRCRWEVELLFRELKTQYELDEFDTSDEHVVRILLYAALLSLLVSRDLLDLVTERADDELVFPTERWAATFRSHAQLILHELGEYLGYSPPPLLERLIEDAQKIHKQRPILQETLATATQPRCEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT6</accession>
    <name>V6DVT6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">30S ribosomal protein S28e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rps28e</name>
        <name evidence="4" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004595321.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38950756"/>
    <dbReference type="GeneID" id="55595525"/>
    <dbReference type="GeneID" id="65213640"/>
    <dbReference type="OrthoDB" id="121548at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_S28e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="PTHR10769"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="7911" checksum="E4BFD76BC62343E8" modified="2014-02-19" version="1">MSAEEGTGDSTTAEVIEVVGKTGMHGEAMQVKCRIQEGSNQGRIITRNVLGPVRLGDVLQLRETQRDADSIGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT7</accession>
    <name>V6DVT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6579" checksum="A028B468F2E55845" modified="2014-02-19" version="1">MYRCELTTTPRYLSDVLVLTATEFGDDAYLRPGSNDRTGDTHSIKLKPLGFLIRTINM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT8</accession>
    <name>V6DVT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15604</name>
        <name evidence="1" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="128" mass="13891" checksum="8AB6988B530A8542" modified="2014-02-19" version="1">MTNTADETASLAIPMDPDVAFNAIGNSRRRRVVLSVSRASKAVSTDELAIEIAAIENAIDPSKVGSDERTSVYIALTQQHLETLDEVGAVDYDDRSKTVTATDATEPLAEYIRRLQTACYKPDSEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVT9</accession>
    <name>V6DVT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2 protein</fullName>
            <ecNumber evidence="3">2.4.1.117</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_10585</name>
        <name evidence="3" type="ORF">BN903_167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004581">
        <property type="term" value="F:dolichyl-phosphate beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="363" mass="39332" checksum="326E0536334EF097" modified="2014-02-19" version="1">MPTLNEEEGIETCLNWIKSAVEELQLPTEIIISDSSTDRTPEIAREMGAIVVEPDGKGYGYAYRYAFERTRGQYIVMGDADTTYDFTQIPRLLDHLEETGADVVMGSRLDGEIKDGSMPTLHQYVGNPLLTQFLNAFYEAGVSDAHSGFRIFTREAYERMDLETDGMEFASEMIMDAGAKDLQIAEVPIVYHEREGEETLDSFRDGWRHVRFMLVNAPGYLFSVPGVLLALFGAAVMAVAHTGVALGEVTLGVNSMIAGSLFTILGIQVGTLGVFATVASDPIQKPGDAVTSWVSTYGTLERGATAGLIVFAAGASYATWLIVDWALNGFAAVPFTTSGLVAFTAIVVGVQLVFSSFFFSAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU0</accession>
    <name>V6DVU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="9079" checksum="0E23974D726D0767" modified="2014-02-19" version="1">MTTTANKIGVHCSCGISFSVNVEEQTVDDWWERKESRSYVETRKSVVCVCLLHAVKLSEQLNRQKRAGPVHVRSTFHSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU1</accession>
    <name>V6DVU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA repair and recombination protein RadB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">radB</name>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="DNA_recomb/repair_Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9493" checksum="F394468EC815906B" modified="2014-02-19" version="1">MTHLLSLARRHDIAVVITNQVFTDPDGDRDRALGGNTLNHWTGAIVRVDRFRGGNRRATLEKHRSKPAGDTATFRIVADGLAEGSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU2</accession>
    <name>V6DVU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_10625</name>
        <name evidence="3" type="ORF">BN903_172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077051.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82590at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="319" mass="33690" checksum="B52608D2D0BDBCFB" modified="2014-02-19" version="1">MDVPGGAATAEESDSGESDAPDPGEFPDRQVRLAALEAENRQLREEYARARQAAYRRTALGLFAVGLVGLVGGLAFPDARTVLFALGGTGVFAGVLTSVLTPERFVSARVGARVVQALRADRDAAIDELGLRGDPAYVPTDGSDRSGGVRLFVPRRADEPLPDPTDLTDLFVVPEADERGGVAFHPTGEPLFEDLDAAHDRSVDATPETTAAVAADALVELFELADSVAHDVDLETNRVTFEIEGAGLGDPTGFDHPIPSVLAVALVRTVDAPVRVDVTDDDPLTVTCRYDPQADAANGRSTATAEQEETQRRTESTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU3</accession>
    <name>V6DVU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02132</name>
        <name evidence="2" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077830.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83701at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="223" mass="23913" checksum="4418E877735A5893" modified="2014-02-19" version="1">MSDRGGRALDGSESPTSNRDTADSLAPTAAESAASTAADAPSTGRLVVVCGLPGVGKTTVAERIADHVDGRIRRTDVIRKELFDDPEYTDAETEAVYDELLARAREDIDAGDAVVLDATFADDWFRAEARETAAETAGAFDLVEVDCDEDVVERRIERRDGISDADFEIHLHFKELFDEVAGDHVVVDNSGTEAETFAQVDAAFAEGATADRDDRAATVTDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU4</accession>
    <name>V6DVU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase involved in chromosome partitioning</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Natpe_4443</name>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="277" mass="30777" checksum="D609F3862E2365EA" modified="2014-02-19" version="1">MLKGGVGKSTIAVNLARQLAAQDHDVLLIDLDPNGHASVGLGYDDEYHNTEETIGDVFFDDADPTSVVYDTGYEFDILPSSEDLEQVEREIVVGDVFQPSGLLKREVVDPLLGNTYDYIVTDSPAYRSRLTDNALVATANLVLPLAPGNEAIAGLERTIERQISPLRQHMDVDVLALVPNMLSGRIDQQTQDRQLLERLNSHDNLQDRIPNFARITDWEAVDAGDLKPSPGIRDRTSITKAYGERKPLLDYDPDCDQLKCFDELAHIVKTGKVVRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU5</accession>
    <name>V6DVU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6920" checksum="55B05DF541DFF93A" modified="2014-02-19" version="1">MIRNPTALGNHTGAKNLCMRNRIRKYDTSGPTADFSSNSQRLDGDLDDRAGRGSGSREWEPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU6</accession>
    <name>V6DVU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5675" checksum="B306B03891CAEF98" modified="2014-02-19" version="1">MGRERSSTWLRFRRRRCQVVRGYVRELHTGVQPSLRGVVRSSKRFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU7</accession>
    <name>V6DVU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pgi</name>
        <name evidence="4" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="19345" checksum="1CBF3002FDF25AFC" modified="2014-02-19" version="1">MMPYAESLETFAEWFAQLWAESLGKDGLGQTPARALGATDQHSQLQLYRAGPPDKLVTLVRPTERADVPIPETDLDGLAYLGGSSLGGLLDAEFEATEASLAAADVPNVRVEIDRVDERSLGELLYGMEAACVLYGELASVSTFTQPAVEWGKKAARGLLGGGDFEEADAVTEKRELRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU8</accession>
    <name>V6DVU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4875" checksum="9D1D990A53D5B609" modified="2014-02-19" version="1">MPSRERSREPHYHFVQNTKPSALKINNFDTTDYSENPLKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVU9</accession>
    <name>V6DVU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">arsB</name>
        <name evidence="4" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077809.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60543at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="392" mass="41996" checksum="79CA311604C21EF1" modified="2014-02-19" version="1">MSDAVHEHGPNCDCESCGDPRSMDFLDKYLTVWIFGAMAIGIGLGYVAPSVTGPIQDLHLVEIGLVLMMYPPLAKVNYGQLPAVFKNVKVLGLSLVQNWLIGPTLMFGLAIVFFSGLVPGLPARPEFFLGLVFIGMARCIAMVLVWNELAEGSNEYAAGLVAFNSVFQILTYGVYIWFFALVLPPLLGMESLVAGISEFGISPRQVFEAIAVFLGIPFAAGIASRFVGTRTKGVEWYEETFEPTISPLTLIALLFTVIVMFAMQGERIVAQPSDVLLIAVPLTIYFVVMFFVSFGMGRGIGADYSTTTAIGFTAASNNFELAIAVAVAVFGVGSGVAFATVIGPLIEVPVLLALVKVALYLQDRYDWQGYTTGQLNEPTADGDGTSGSTADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVW3</accession>
    <name>V6DVW3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Archease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023572">
        <property type="entry name" value="Archease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036820">
        <property type="entry name" value="Archease_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01951">
        <property type="entry name" value="Archease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69819">
        <property type="entry name" value="SSF69819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Archease" evidence="6">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5722" checksum="E01D92969FCE644E" modified="2014-02-19" version="1">MPCLPRLADGERATASRSTRSPPGRSRAVTYSEMSLERRDGGWYAYVVFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW31</accession>
    <name>V6DW31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11175" checksum="03FCD99A946FC495" modified="2014-02-19" version="1">MPSKSCSPFRCLLSVPPRPFFVSPRPFFVSPRSVPRPGDFHPIAFLSVDAERRAVASSSATPNFLGRPKNRWFFDVLGGPNIYETFGRRPRRPSAGGDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW32</accession>
    <name>V6DW32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5009" checksum="9A1DA0B10EC1D50E" modified="2014-02-19" version="1">MRGGARRGSCEAGAGDVSTAASERSERVRSAASVRPPRGWGFGGLCVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW33</accession>
    <name>V6DW33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06175</name>
        <name evidence="2" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077922.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="131337at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7237" checksum="CCD35123382C775D" modified="2014-02-19" version="1">MERSRFVSLAVAAFGLVFASFLLRGVTRLVAPYEVAVAVSAPVLFAAAALLVALFVLAVLDATGIRPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW34</accession>
    <name>V6DW34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HpcH/HpaI aldolase</fullName>
            <ecNumber evidence="5">4.1.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_04887</name>
        <name evidence="5" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.24" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077974.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60831at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043959">
        <property type="term" value="F:L-erythro-3-methylmalyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050083">
        <property type="term" value="F:malyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="4">
        <location>
            <begin position="13"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="303" mass="32666" checksum="905BAD26EFA96117" modified="2014-02-19" version="1">MTDVTLRRTQLATPASDEKMMHSAADSDADEVFLDLEDSVAPDAKPAAREPLIEAAREEDWSDKVLSFRMNGIDTKWWYDDVITVVGEAGEYIDDIIVPKVKSASDVHTVENLLAQVEENNGLEVGAIGLEPQIEDGEGIHNVHEIAHASDRLSSIIFGPGDYSAAMGTPGLDIGQFPEYPGHYWHHALSECNSAAKSAGLPCLDGPYADIEDPDGFRESASNANMIGCDGKWAIHPSQIEIGNEVFAPDPETAERAKRIVDAYAEAMEEGKGAVSVDGQMVDEATNKMAQDIVEKAEAAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW35</accession>
    <name>V6DW35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06130</name>
        <name evidence="1" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077931.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111150at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12485" checksum="ADAC105264B10BA7" modified="2014-02-19" version="1">MATASIPPTTEARDVFRELGYTVSEGGREFVAERKWRRVLVTVLCLDDDDLDPYLADGGETPRLRCFVTWRDRAADLQDRLVSAKPPYDWAVIGIDHDGEDFAVMEGAPGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW36</accession>
    <name>V6DW36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_10566</name>
        <name evidence="3" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077936.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="291" mass="29641" checksum="6B3526489B9FB465" modified="2014-02-19" version="1">MTDPSSGDPASDGGVSEEFDDIDPDAVSDDADGPKGTGGSPGIAVVTALVLGVLGPLIAVASGGLIYAINVVSGGLSLAASVVLTLVFGQYVAFGGLAIGYLAWRGFDRDGIIEYLGVRVPSLKEIGIVLGSWVLILISVLVVSTIVQLLGTETAANSSAELAMGNPSIIPLFIAASFLVIGPCEEILYRGVVQGRLRESLPAAPSILLSAAIFAAIHVIALTGGVSAQLTTVSILFVPSLVFGAVYEYTGNLVVPALLHGLHNAVLFTALYVVVTTDPSQMPAVVGFLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW37</accession>
    <name>V6DW37_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11419" checksum="FC969874A04632DC" modified="2014-02-19" version="1">MMRRWRSKSFRDPAVRRGRRCDHRGPFTALRTPSTDRSIGFDRESDRGSYRRIVGVFGDDGPDRSKRVPGSDRALVPLAAANTRIFGRASGMRHRNGREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW38</accession>
    <name>V6DW38_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_04722</name>
        <name evidence="5" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA damage repair.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nre family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077960.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17407at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02096">
        <property type="entry name" value="Nre"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033167">
        <property type="entry name" value="Nre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006979">
        <property type="entry name" value="Nre_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006978">
        <property type="entry name" value="Nre_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38136">
        <property type="entry name" value="PTHR38136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04895">
        <property type="entry name" value="Nre_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04894">
        <property type="entry name" value="Nre_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nre_N" evidence="3">
        <location>
            <begin position="20"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Nre_C" evidence="4">
        <location>
            <begin position="330"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="442" mass="48238" checksum="2A8CD12C00BCA6AD" modified="2014-02-19" version="1">MRLDEFIEFEANERAERRRLAAEKDYGILDHLDSFERRFDEHVSDDAVVGSVSPSIFVGRADYPNVSTGLLSPVGREERAAAFETSAAWYDEGVSITDVFDRRTSLLNSTRGVDVADAGTTSGATSVGGGSGSAESVHDAWNGWLGVQREVAIADRPVDVEIGLDGRPDLDFEVGTEDIKTPTGPRAAARTADLGENPHVPRPVKKTLEDDDWRAEGAMTYLYRRGFDVYEINTILSAGALGRGENRRLVPTRWSITAVDDTVGQFLRGSIRSNPAVDGVEVHRNEYLGNAFWVILVPGQWEYELVEMKSPGSIWNPDPEAGVYLAAASEGREGRTGYVEETAGAYYAARLGVLEHLDDRGRQAKALVLRHVSDDYWGPVGVWQVREAVRNAFDGELGTAETFGEAVRGVADHLPVSLARLRRKSTLAAGLQANLGDFVDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW41</accession>
    <name>V6DW41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05769</name>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="170" mass="18777" checksum="918DCE25DD36F891" modified="2014-02-19" version="1">MKEVVVEYDEGWFVGGYDRVEQPDGTEKKYYWAELSPATVIVAVADDRVLFVEQYRPTVRNTQLELPAGIVESGESYTEAGARELAEETGFEPDSTALLQEVWCSTGVLRHTRGYVFAEGLTPVDVDHDSNEFLAPRAVPVEEALEIAGEPPTNDATLEGLLLAEREGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW42</accession>
    <name>V6DW42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9266" checksum="C821E7AEAD1A09BA" modified="2014-02-19" version="1">MPSRDPIRSLSRSGVVGTLRITGLRKVAVRSGNISTGQRRCPERGAIKKDRVWIDPRGPMVGSYESRPSGNDVSRCGGSRSAQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW43</accession>
    <name>V6DW43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_08262</name>
        <name evidence="1" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5327" checksum="D366DD3B08648FAF" modified="2014-02-19" version="1">MPTCEHCETHVSERFVRVFSDARGRVHACPNCSANAGIAEVAKERAPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW44</accession>
    <name>V6DW44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="7178" checksum="7ED930AC3944C068" modified="2014-02-19" version="1">MTARTRRRPPRPHECRADTRAIGTTRETREFVLNSARPELEYVCDGVQRGREHLTDGRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW49</accession>
    <name>V6DW49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_14835</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077975.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75144at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="266" mass="28481" checksum="32BF6BDED00876A2" modified="2014-02-19" version="1">MSGDEDEPRPATYYHLARAVLYREFLIFVRYPANAIGGIVVSLFFFAALFLGGQLLAGQALTDSIEGIVVGYFLWTLSVGAYSSVSNDIGSEVQWGTLERHITTPFGFAPVALLKGVAKVVRTFLTSAVILAAMLLATGTRLSLAPVTVVAVAGLSIVSVLGLGFAAGGVTVLYKRIGNWLNLLQFGFVALISAPVFDLPWTRVLPLAHGSAMLQRAMVDGIRLWEFPLADLGLLVAVAVGYLLGGYLVFQLATRRARRLGVLGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW50</accession>
    <name>V6DW50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_12591</name>
        <name evidence="2" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077166.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121854at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="11274" checksum="6E21280A1CC85EA0" modified="2014-02-19" version="1">MGSDNVKHETGERGPGPDVSFGPLKRALREHRYPVTAAELIEQYGAAELETPTATERFGGLLEDCEETQFRDPSDVRGAVLDALGYADASPERPSDDWTSLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW51</accession>
    <name>V6DW51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Branched-chain alpha-keto acid dehydrogenase subunit E2</fullName>
            <ecNumber evidence="3">2.3.1.168</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08194</name>
        <name evidence="3" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.168" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043754">
        <property type="term" value="F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="3"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="22623" checksum="78213BC2419A2DFB" modified="2014-02-19" version="1">MTIKEFKLPDVGEGVAEGELVSWLVAPGDRVEEDQPVAEVETDKALVEVPSSYDGVVEELFVEEGEMVPVGDVIISFRVDEEGGEAVDAAAGDAEAGGGESDSSAGEEAEPEPSAGDESXXXXXXXXRRRRPNRTRPNPPEPNPSRATPNRPTSGTPASPRPTRRARPPPATRPSPTGASGGPSASRWSGRSSPRRTSPTTTPPRSTPSSTRARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW52</accession>
    <name>V6DW52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4177" checksum="FC1AFCFC61218CED" modified="2014-02-19" version="1">MSRATVWREKSGSIATETPKRTKTRGVPDKEFSPAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW53</accession>
    <name>V6DW53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6554" checksum="ACB72D2F096377D9" modified="2014-02-19" version="1">MEARRDDELRARHQRGPGGLAVEDRPGADDDLVVEGAGDLAELLCHVRRVGGDLHGGDPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW54</accession>
    <name>V6DW54_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsJ</name>
        <name evidence="4" type="synonym">rps10</name>
        <name evidence="7" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004048854.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38741773"/>
    <dbReference type="GeneID" id="55719260"/>
    <dbReference type="GeneID" id="65214719"/>
    <dbReference type="OrthoDB" id="107993at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_S10_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="6">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="11430" checksum="ED7D2B9DA7CF2563" modified="2014-02-19" version="1">MQQARVRLAGTSPEDLDDICDDVREIADSTGVALSGPIPLPTKTLEIPSRKSPDGEGTATWEHWEMRVHKRLIDIDADERALRQLMRVQVPNDVSIEIVLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW56</accession>
    <name>V6DW56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_08379</name>
        <name evidence="1" type="ORF">BN903_140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077207.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105171at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="161" mass="18247" checksum="CFE577A6AB080371" modified="2014-02-19" version="1">MSVSQRVTSDDQLARLLQIGIVLEEVVEARTHRHYQQLDAELDAEVEALLADAAEESADHRERLEALIEGLGVESVPFGEIESLVDARYGRTRPEDFDDVLYDQLCNEETAYKFYDDLIEAIEGSDVAFSIDREELLATLTAIRDDEAEGVREVTEVMERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW57</accession>
    <name>V6DW57_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_08485</name>
        <name evidence="8" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="50"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="30119" checksum="E9437581A234B5DF" modified="2014-02-19" version="1">MTADATDDARAADAEADSNAETEADPETGTDSDADATAGTTHAIDGDAILRIRDLDAGYGDLQILSDVVLDVADEEYVTIVGPNGAGKSTVMKTVFGLTTHMGGTVEFEGEPIHGLAPEQIIREGIGFVPQNDNVFPGLSVRENLEMGAYILDEVPEDQIEAVYDRFPILRERSEQKAGTLSGGQRQMVAMGRALMLDPDLLLLDEPSAGLAPDLVSDMFDRIDRINESGTAVLMVEQNAKEALRRCDRGYVLVNGGNRYTDRGDVLLADEDVRRDFLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW58</accession>
    <name>V6DW58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA double-strand break repair Rad50 ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rad50</name>
        <name evidence="2" type="ORF">BN903_147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="1">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="18362" checksum="71B98FB55347D10C" modified="2014-02-19" version="1">MKFDRVRLVNFKPYGDADLRLTEGVTVVHGLNGSGKSSLLEACFFALYGSKALDGTLGDVITNGEEETEVELWFTHDGVSYRVERRLKSYDGRIDHQCTLEATDGSDVTRDGARAVREFVTELLRMDAEAFVNCAYVRQGEVNKLINAPPESDRTRSTTCSNWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW59</accession>
    <name>V6DW59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6271" checksum="B5236C4CDF5D1B44" modified="2014-02-19" version="1">MASKSYADIGYLWTLSVGKDGSAVPWRAPPRPYRGRGASREGVAGSRSEAEGASDEVGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW60</accession>
    <name>V6DW60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08981</name>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6640" checksum="385BEF06438BECE5" modified="2014-02-19" version="1">MTEPEGVYPELERFRLYVVTQATVLASGWFAGTAARGRYAALLHSGALVACCYVVFTVGGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW61</accession>
    <name>V6DW61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_08404</name>
        <name evidence="1" type="ORF">BN903_145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6180" checksum="6E43070D4EB83C5B" modified="2014-02-19" version="1">MSSDPRSESQAARPADLDAVDDEVEVYEDDGNVVIFDATNPLAWVEASRTVRLADAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW62</accession>
    <name>V6DW62_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lipA</name>
        <name evidence="9" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077604.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42664at2157"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="67"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="326" mass="36214" checksum="222EA543067EC1FA" modified="2014-02-19" version="1">MQRGRRKPDWLKSRPPSGSRFTEIKSTLRDHDLHTVCEEANCPNMGECWSGGANAPPNGEAADAAETGPGTATFMLMGDRCSRGCNFCDVETGGMEPLDPDEPANVADAVAEIGLDYVVLTSVDRDDLADAGSAHFAETIREIKRRDPEVLVETLIPDFGGDPEAVRRIIDAEPDVIAHNVETVERLQWPVRDRRANYEQSLAVLDQVDRESDIHTKTSLMLGVGEYDHEVYRTLGDLREVGVDVVTFGQYLQPSRSHLDVFEYVHPDVFETWRRVAETEFDFLYCASGAMVRSSYKAGELFVEALVREGRSPEDARRHARAAGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW64</accession>
    <name>V6DW64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04997</name>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077981.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66643at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="222" mass="24158" checksum="B738ED8C7666BF5E" modified="2014-02-19" version="1">MDEKTADLRDLFVDTTGSESVTERQDAARGTLIDSDEASVDATALDLVAAMRERYGFSTDLDNAAYVLVARGRFEDDDDAETAAALRDALDEREEADIDPTDVDAETVRKMRLDLHLVRDADREADSDGAGDDFAYADLKRLTGAGNSIVECAAELGATPDRVARYAAVARTDIASTRANDRFRDTFRDLFTDADIEGSLASDAREDGLKEATEDIETDVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW66</accession>
    <name>V6DW66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">H+transporting two-sector ATPase C subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C473_01139</name>
        <name evidence="8" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077988.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130056at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="7">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="8315" checksum="67866BB8AF5B7B43" modified="2014-02-19" version="1">MFEATNELGNLVLSTGGTLTDPNAAAALAVGLAALGAGYAERGIGSAAVGAMAEDEDLFVNGLILTVLPETIVILALVVVFIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW67</accession>
    <name>V6DW67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">IS1341-type transposase (TCE32)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C473_08902</name>
        <name evidence="8" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077609.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="188"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="302"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="405" mass="46308" checksum="B441366CBCCCA8E6" modified="2014-02-19" version="1">MADDYLRRTAITRLVLTDEQRKLLDTTIFDWKRACNISSRIGWRADEARKTRLQKLAYDEVREETRLGSQHTILATHQAAAALDGIDDIESLKENHTTSCPEFTADTVKYDTRTMTLFDDGTVSLSTVEDRVRCELALPDDEDGYQYQYLDSETWEVTESTLSRRDGAYYIHLGFRKPKPKKRAEIRDDTEDRTVLGVDLGIANIATTSTAYFASGDELRHRHREFERIRGRLQRTGTQSAHRTIQQMSGRESRHVRDTLHNVANDIVDEALEHDCEYVAFENLRHIRDRAPRVKEFHQWAHRQLVDMVESKADAEGLCVVYVSPENTSRRCPECGHTSKGNRITRSEFKCKSCDETGNADYVGAKNVGLRYVRRGLQSSRRTGDSQLALKSGTVTPNRGFVPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW68</accession>
    <name>V6DW68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_04030</name>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077212.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81179at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="199" mass="21966" checksum="6DF0C095BDABF6AC" modified="2014-02-19" version="1">MYELTPQFDAEVDPGTNILLTGPPLSGKRSMMMDILAAGTDRDEGAIVVTTKDGADRVLRDYEKRTPYEGKPVAVVDCVTRQQGGETRESDRIKYASSPVDMTGIGIKLSEFLQAFGDRGIERNRVMVHSLSTLLMYSDLQTVFRFLHVFTGRVQSVDGLGLFSIDSTAHDDQAMNTLKQLFDGIITVTEDGEPDIRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW69</accession>
    <name>V6DW69_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDDEXK_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14714</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="364"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="743" mass="83126" checksum="6A3B755CD5E3D10C" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW83</accession>
    <name>V6DW83_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">V-type ATP synthase subunit C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">V-ATPase subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ahaC</name>
        <name evidence="9" type="synonym">atpC</name>
        <name evidence="10" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077990.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75042at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00314">
        <property type="entry name" value="ATP_synth_C_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_su_c/d_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014272">
        <property type="entry name" value="ATPase_V0-cplx_c_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_su_c/d_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_suC/d"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="SSF103486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02923">
        <property type="entry name" value="AhaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="348" mass="38671" checksum="E644AB63E7455666" modified="2014-02-19" version="1">MSAAGSPNPEYVVARVRARRGSLFGDDEYRKLTRMGPAEIARFMEESSYGAEINALGSRHGGVDLIEYALNRNLAEQFDAILDWSEGSLYDLIARYLRKFDAWNVKTVIRGVYTDAEQSAVEVDLIRAGEFDDRRIRRLLEADSIDGVIEVLEDTIYGEPLREAYAEFEETGVLVPLENAVDRAFYERLLSGLGGDEPTRQYEAFLKAEVDFRNATNALRLARSGADIDPAAYFIEGGDLFTRSSLARLAQNIDELVEYIGDSQYGDELGPALRELEEADSLIAFEHAIDAALLAYGDRLGTIHPVSVTPVISYILAKERETENIRAIARGKEAGLSPDEIESELVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZZ3</accession>
    <name>V6DZZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5860" checksum="9C4A489415A413D5" modified="2014-02-19" version="1">MRRVSAVLSSIKILRILAAVTNPAGRRGPTRLAAVSPAATRSLFTRAGGRRTHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZZ7</accession>
    <name>V6DZZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6528" checksum="60C4B7E1035027E4" modified="2014-02-19" version="1">MAVSLASRRRPGRYGKATGFAAAPPSTALPVVADATGPPVARRNASALRAAGVASRTVVRRRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZZ8</accession>
    <name>V6DZZ8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit Rpo12</fullName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit P</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">rpoP</name>
        <name evidence="8" type="synonym">rpo12</name>
        <name evidence="9" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004049526.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="SMR" id="V6DZZ8"/>
    <dbReference type="GeneID" id="7401700"/>
    <dbReference type="OrthoDB" id="129924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00615">
        <property type="entry name" value="RNApol_arch_Rpo12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023464">
        <property type="entry name" value="Rpo12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="DNA_RNApol_7kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="SSF63393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 8 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5050" checksum="D6140DCAA4CADFBC" modified="2014-02-19" version="1">MSYKCSRCKRDVTLDEYGGVRCPYCGHRVLLKERGGDVKEVNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRE7</accession>
    <name>V6DRE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5740" checksum="3367B6485053FBB9" modified="2014-02-19" version="1">MGPGRRGAGANANRRGTRRRGLKNGVRGPRGRSYTERGRFGFRLTQLSATHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRE8</accession>
    <name>V6DRE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transporter SCO1/SenC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C469_00670</name>
        <name evidence="4" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076544.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80199at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="49"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="228" mass="25333" checksum="DF9975957FE04D7D" modified="2014-02-19" version="1">MDRRTFCKSTGAIGATIGTAGCLGVLGDKGAEGTVLGPPEQDLSEAVHPSYGDEMPHFTVPDPITNEEISISEYEGERAILWTSFYTNCPDGVCPALILRLRRAQEAATEGGYSDEAVFLAQTFDPERDTAETLREYAGQQGVNLDANNWHFLRPESYERGQELLDEHFGLKIEKASADQYENLEYQFPHYGLILLANKQGIVERAYPRGPQTDIERLVNDVEQVTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRE9</accession>
    <name>V6DRE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="363" mass="39300" checksum="D0FC07B42A59EC92" modified="2014-02-19" version="1">MALVEVEVVEDRVGQLLGDRVGGHRLGALRARLAVDTDAEFDLVVAQIEGRLALLRGDTGGERGAHRPDVVDHLLGDACDLVEVGPLRGLRAGGLVDEDRPADAPAAGGVQRVLDGHVVVHHDACDLDALHLREFDGGLEVHHVALVVFDHREDAVARVAGPDQFLELVGGRRGEHVARGRPVEHPVADVPRVGRLVTAPPPVTIPTFPSTGPSSRTSTWVSGSRRSRSGCAAVIPSSISSTTSSGSLISFFMYDRTDSPGPVKRSGGRGRRRPSAVSSARRRACRTPDSGTRPRRFGRRRGTRGRSRSRRRRRTRPPPVRCRSTRRPGRRTRRRPTVSARRSGGPSGSARRPESRPCPARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRF1</accession>
    <name>V6DRF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.33</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_00971</name>
        <name evidence="3" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076554.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50204at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="332" mass="35798" checksum="DAF4D2879E73F0A4" modified="2014-02-19" version="1">MTGKATARAHPIQGLVKYHGMRDEELRLPYHDSISLCTAPTATTTTVEWQPDASEDVYVIGDEEVGGRAAERIDMVVDHVRDLAGVDAAVRLESENSFPSNIGFGSSSSGFAAAALALVEAAGLDRSLPEVSTIARRGSSSAARAVTGAYSRLDAGLNDEDCRSHRLDVGVSGDGFDPEEDLRIVAAHVPAYKETEEAHREAAASHMMQARTAHVQDQLVEMTDALREGEFDRIFETAEHDSLSLTATTMTGPSGWVYWQPETIAVFNAVRELRESGVPVYFSTDTGASVYVNTLADHVDEVESRIAEVGIDTDVWEVGGPARVLDESDALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRF3</accession>
    <name>V6DRF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075965.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="9621" checksum="D6D56E98A6C02E09" modified="2014-02-19" version="1">MSAEFIHDPEGIIVFAEPTTLQVSSGCAESTVTATVLPFSKRNDDSVWAGPDTYMIPEDADFTVLDGLASLSATDAETVDVGDRLEAAEPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRF4</accession>
    <name>V6DRF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="5697" checksum="7133BE2D75D93B20" modified="2014-02-19" version="1">MVGDVPALGTDDGALVAVADDEPPVRQGALETTLRTEEDRLPAGGPGTAGVCVHVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRF6</accession>
    <name>V6DRF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_00986</name>
        <name evidence="3" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076556.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109503at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="11966" checksum="44358E7921C58FD7" modified="2014-02-19" version="1">MTEYTVEFVGTGETIEVADTETILSACFDEGIAQEYSCRVGMCLACSAEIIDGEVTQPAARGLSDEEAEKYALTCMARPQSDLTLDRGKYPPSIENDAATPAEDGDGAAADDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRF7</accession>
    <name>V6DRF7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protein Pan1</fullName>
            <ecNumber evidence="4">1.10.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pan1b</name>
        <name evidence="4" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.2" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076547.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19077at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052716">
        <property type="term" value="F:hydroquinone:oxygen oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="111"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="2">
        <location>
            <begin position="241"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="384" mass="42017" checksum="0FF97802A2C56213" modified="2014-02-19" version="1">MTRSFGAPGTGLSRREFLTATGATGLSALAGCSSKAINAPTAAAGGPNEAQTSSDLPYTSPPTVVNVDEQGGSVTMGTQPARHAVHPLDSMGGPVEFPRVWAWQADDNDPSVPGPILRTTEGNDMEVTLDNTNGRRPHTIHFHGVTKTWKNDGVPTSTGVQVPAGEKHTYEIPANVPGTHLYHCHFQTHRHIDMGMYGIFRVDPEGYEPADREYFMTIKDWDSRIPKKWAGEADFTFDTASRNPDVFTVNGKSAPRTLHPEQGSPIIVDKGDLVRIHLVNGGYMSHPMHIHNHRFQRVEKDGGIVPEAARHDIDVTNIAPAERHTIEFTADADPGIYLMHCHKVNHVMNGSFYPGGMLTGIVYRSVMDSDIFSQLMDYAGYEPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRG1</accession>
    <name>V6DRG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6741" checksum="87B67A77EE83FF07" modified="2014-02-19" version="1">MTVRLCRERLGATASADSDRGRDHPNYGSRNRRLGGVHVREYRFRVPSRGIQDTADALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRG3</accession>
    <name>V6DRG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C473_04729</name>
        <name evidence="7" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076551.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106422at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="262" mass="28202" checksum="18308122E2AC5D45" modified="2014-02-19" version="1">MPPAQFAVPEFLLAVPYRIWLALAVLALGLVLAYLTGVINRRLLERAGVPEVIEGTAFERTAREFDTSTVRIVAKLSSYFILAVSVIVALTVADVNYLEQFWSGVAAFLPRVFVAILVFIVGVVVGDKVELLVAERLRGIKLPELGVLPSIAKYSVVYVAALIALGQVGVQTLALIVLLAAYAFALVLFAALATKDLVASAAAGVFLLLRQPYGIGDEVRVAGERGVVQEVDLFVTHIETGGEEHVIPNHAVFRDGIVLIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH0</accession>
    <name>V6DRH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_00991</name>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076557.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116723at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="16820" checksum="D463F089B1C0D6DB" modified="2014-02-19" version="1">MSPSTRTLGSRTVSGILLGLLVLGVVLLAFENVPGTSFRSANVELFAVFILPLAISLVAYVGLGRSVVWWELALLAVWGAISVSVATFVGFFATMGTPGGYPGAAAEFVRDVAMFLALTVGLGVPYGLAGRLRREHPRWAVASALGAPVGSLVLFNVVAVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH1</accession>
    <name>V6DRH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00574</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076537.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49385at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_domain" evidence="1">
        <location>
            <begin position="39"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="302" mass="32679" checksum="AE98BA841E72E017" modified="2014-02-19" version="1">MDRRRYLQAVGISGTISLAGCLTNSSTADAPDVTGDTLTLATATTTHDSGLLDELLPGFQDRFGTQVDTVVRGTGGALQTARAGDCDVVIVHARPLEDEFLRTGAGINRRQVMVNDFVVVGPADDPANIAGEDPVTTFQRIAEAEVRFLSRGDRSGTHLRERQLWAEAGIDPSGSWYSETGQGMGNTLNLATQTEAYTLSDRGTFLNVIEDTLEAHVNYGIESPPALLRNEYAVIPVNPARHDVAYPLAMAFVGYLTGPAQTQISEFRIADKRAFRSLTPSQEPEFGQYIPSDWQTETNVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH3</accession>
    <name>V6DRH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine synthase</fullName>
            <ecNumber evidence="3">2.5.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_11769</name>
        <name evidence="3" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076565.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47519at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="2">
        <location>
            <begin position="11"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="305" mass="32147" checksum="C79DDD3FE893206A" modified="2014-02-19" version="1">MDDDILSTLGSPLVRVDAPAGTTVAAKVESRNPGGSAKDRPALYMIEAAEEAGEIEPGDRIVEPTSGNTGIGLAMVGATRGYDVTLVIPEGKSIERRRLMKAYGATVKLVDGDISDAKDRADEIEREPNTIQLRQFENPANPRAHYETTGPEILDQVGDRTVDALVAGVGTGGTLSGIGRRLREAFPDVRIDAVEPSDNAVLSGGEPGNDGFQGMGPGFVAPNLDVDLIDEVHTVDLADAEVECRRLAREEGILVGQSSGASNLAAKDVAAELRETGDFAGEEPLVVTVFWDSGERYLTAGTFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH4</accession>
    <name>V6DRH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4949" checksum="A4CBA99AC9B636E5" modified="2014-02-19" version="1">MSVTDRLVSSGTILDKQIQSSAAMTAGNFCSADPAIVRVRESHQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH5</accession>
    <name>V6DRH5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aspartate carbamoyltransferase regulatory chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">pyrI</name>
        <name evidence="10" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in allosteric regulation of aspartate carbamoyltransferase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Contains catalytic and regulatory chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PyrI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076560.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101957at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009347">
        <property type="term" value="C:aspartate carbamoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00002">
        <property type="entry name" value="Asp_carb_tr_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020545">
        <property type="entry name" value="Asp_carbamoyltransf_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002801">
        <property type="entry name" value="Asp_carbamoylTrfase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020542">
        <property type="entry name" value="Asp_carbamoyltrfase_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036792">
        <property type="entry name" value="Asp_carbatrfase_reg_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036793">
        <property type="entry name" value="Asp_carbatrfase_reg_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35805">
        <property type="entry name" value="PTHR35805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01948">
        <property type="entry name" value="PyrI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02748">
        <property type="entry name" value="PyrI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54893">
        <property type="entry name" value="SSF54893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57825">
        <property type="entry name" value="SSF57825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00240">
        <property type="entry name" value="ATCase_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PyrI" evidence="8">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="PyrI_C" evidence="9">
        <location>
            <begin position="103"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK38799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16558" checksum="24C2E27648022489" modified="2014-02-19" version="1">MSEHELRVSKIRDGTVIDHVEGGQALNVLAILGIDGSEGFGVSVGMNVPSDRLGRKDIVKVEDRELSQSEVDVLSLIAPEATINIVRDFEVVEKNRVTRPDSVTGVLSCPNRNCITNADEPIETRFDVVADGVRCDYCATILRADIADHIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH6</accession>
    <name>V6DRH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase</fullName>
            <ecNumber evidence="1">1.1.1.184</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_10069</name>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.184" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="313" mass="33364" checksum="30F5F3F7ADA1DD9A" modified="2014-02-19" version="1">MRSYRAICMNRPEEIAGVADVDCSGMQALVTGSTSGIGRAAALALGRLGADVLVHGRDQSAGATVVEELNEIGVDSQFVKADFANPDSVRELAATVQQETDGLDILINNAGGFFREGQLTDLGIEYTFHVNHLAPYLLTTELLDHLVDGSRIVTTASAAHQGTQLDFTRVRTVHDYSAMWAYRHSKLANILFATELANRLEALNQSIVSNCIHPGAIPGSGFGRFLPGPFPRILQALDRFPVVTSVAEGAAELLVPALSSEVSGVSGAYFKDQRPATPSRAAQDATVARRLWEVSAELLEIETPLSSATTTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH8</accession>
    <name>V6DRH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Geranylgeranyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11729</name>
        <name evidence="1" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9777" checksum="ABF990BF6CE7990D" modified="2014-02-19" version="1">MRAADVAAAAIDPRDPSTLADYESGWREELSTEIRLGKAIRRCYSLPEPVQRVGLRALSGEIGVHMDEPSSFFSASNLRALFSRSDPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRH9</accession>
    <name>V6DRH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14937</name>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="174" mass="18124" checksum="72BF7B4A4ED38BD9" modified="2014-02-19" version="1">MGVPFALVGLYVWITATPDTGIFATHSGVDSPLLFVRFLAFVLLFGTAYLSLAAAVSALASSRRSAIALGLLALLVGVLGGDLAILRSLAGGMSPEEIAGAITLTPNGAFRGLIFEHVIGVAFTPDGRFVQTSRAVGSLVVWILAGIAVAVTTLTYAARVDVVVERARERFGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI0</accession>
    <name>V6DRI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">xerD</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="216" mass="24627" checksum="2AA4902788879A7E" modified="2014-02-19" version="1">MFVLAYTAVRVGELLRDPDDPRRRGVRWEDLSLDDGSMDVYRKKQQWDAASLPEPVISPLKSYHQLLNPPTDRWPVFPTFDQRTLADLIKTELSDLGEQPEAIDDRREEYARDFLLALELDICPPSITTDGARSILRRLTESAEIDVGHPKHEYLAPHGGRRGMGEVLVRAFGYTVAARYLDNSEEMVRERYSHIEAGELGDIATEALYEVDVDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI1</accession>
    <name>V6DRI1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ThuA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_07082</name>
        <name evidence="3" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076562.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51041at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009381">
        <property type="entry name" value="Trehalose_catabolism_ThuA_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030013">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="247" mass="27867" checksum="2D962D815AB04005" modified="2014-02-19" version="1">MARVTVWNEYRHERESDVVADVYPDGIHAVVAEALREGGHEVRTATLDEGPDHGLSESVLDDTDVLVWWGHAAHDEVRDAVADRVHEHVLDGTGLIVLHSAHYSKIFKKLMGTSCSLKWREAAERERLWTIEPSHPIADGIGETIELDETEMYGERFDVPAPDTLVFTSWFEGGETFRSGCCYRRGSGKVFYFRPGHETYPIYYDEDVRQVLRNAVDWAAPGDGPTPTFGNAEPREEIDTGDDRTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI3</accession>
    <name>V6DRI3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">grpE</name>
        <name evidence="5" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14426" checksum="11AD3F6C0DF36C32" modified="2014-02-19" version="1">MKADFSNYKERAKRKQAEIRERASEALVERLAPVRNDLLRALDQEEGSDLRPGVESTLEKFDEVLAEEGVESIEPDPGEAVDPARHQVMLRVDSDRPEGSIHEVYEPGYEMGDRVLSEAKVTVSTGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI4</accession>
    <name>V6DRI4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription initiation factor IIB</fullName>
            <shortName evidence="5">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">tfb</name>
        <name evidence="8" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075780.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35979at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="repeat" description="1" evidence="5">
        <location>
            <begin position="164"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="7">
        <location>
            <begin position="164"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="5">
        <location>
            <begin position="258"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="7">
        <location>
            <begin position="258"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="351" mass="38684" checksum="1CF7CD08C84E7864" modified="2014-02-19" version="1">MINERTNRKRPNIVSHKNGTDESSSSEARNRRSVTDSVSEENTDRQSQNRTRCPECRGRLRRADDDVDAVCEDCGLVVPDTALNTSVTLYTPNGTDDEESRVGPSSTNLLHDKGLSTTIGWQDADAKGNALSGERRQQVRRLRKWNERFRRRTSSDTNLMHALGEINRMASALGVPNSTRETAGVVYRRALDDGLLPGRAVESVATAALYAASRMDGIPRSIDEVSTVSRVEQIRIERAYRHVSRELGLEIAPTDPRSFIGRIASDVECTDATEREARQLAETAIENGVHSGKHPMGIAAGALYAAAKRCGESLRQADVARVADLSEMTIRNRYPEVLAAADAENVQPQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI5</accession>
    <name>V6DRI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4524" checksum="D579DBE7D19FDE4B" modified="2014-02-19" version="1">MNIVSTLQTTELVLTGVVWTIIQLPVSTMPLLFNNSVAIYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI7</accession>
    <name>V6DRI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mandelate racemase/muconate lactonizing enzyme family protein</fullName>
            <ecNumber evidence="2">4.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11739</name>
        <name evidence="2" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.6" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076568.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18921at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050401">
        <property type="term" value="F:xylonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034624">
        <property type="entry name" value="Xylonate_dehydratase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00564">
        <property type="entry name" value="xylonate_dehydratase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="165"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="412" mass="45972" checksum="27AB565E6973A171" modified="2014-02-19" version="1">MSRNYESLHDPNAEYTMRELSAETMGTTGTRGGGRDVEITDVQTTMVDGNFPWTLVRVYTDSGVVGTGEAYWGAGVPELIERMKPFVIGENPLDIDRLYEHLIQKMSGEGSVEGVTVTAISGIEVALHDVAGKILDVPAYQLLGGKYRDEMRVYCDCHTEEEADPEACADEAERVVDELGYDALKFDLDVPSGFEKDRANRHLRPGEIRHKAEIVEKVTERVKDKADVSFDCHWTFSGGSAKRLADAIEDYDVWWLEDPVPPENLEVQEEVTKSTTTPITVGENRYRVTELRRLIENQAVDIVAPDLPKVGGMRETRKIADVANQYYVPVAMHNVASPIATMAAAHVGTSIPNSLAIEYHSYELGWWEDLVEEDIIEDGYIEVPEKPGLGVTLDMDTVEEHMVDGETLFDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI8</accession>
    <name>V6DRI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport system inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_01121</name>
        <name evidence="7" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076577.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57718at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="116"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="321" mass="35859" checksum="D3523B6EFB10D5FA" modified="2014-02-19" version="1">MTDTHNPDDSTDADSQPKTDGGRVYHEPPETAPTAEGSAIERLRASVPRGPRALRYVVAIGVALLWLVPLVGLFMASVRPLDQIIQGWWNFETFTVTFENYARAWTFQSGPMRQAMWNTAIVTIPSVLAVTLLGTMVAYPFARFDFPLKTGLFFLLIVVMAAPPELVAMGNYNTLRTTGLFDTYMGLILVHIGWGMGWVVMFLRNFLLGLPEELEEAARIDGASRYQIFKSIVLPYSAPALVSVAVIQFTWVWNSFFFPLVFMRSRENQLAPQVLPLMKGRLQIDWGLVAAGSVLTMIVPILLFVTLQRYYKQGMVAAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRI9</accession>
    <name>V6DRI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5428" checksum="2AA1B65DA1CBE745" modified="2014-02-19" version="1">MGTLSNDRYSVEGAGNVVRKVVTTHELGPSRSPNPRFRGTSRPCEPAKSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK1</accession>
    <name>V6DRK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11674</name>
        <name evidence="1" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076578.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87470at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="17621" checksum="ABD0499AB9D5E01F" modified="2014-02-19" version="1">MSEDPATDAVPDAHATEGWQAVMADMAATADAYRDRGWTAVELHPGDSVLVDSAARTGLDVVVPGPEYEELEAIAGESEFTDVETFRAEEGGLVYLLIVERDPENETAVLVPAYYDPGGSEPKLDAVRESGEFALFCRRLSDEYVLFVHTDIAPFLPAGLADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK3</accession>
    <name>V6DRK3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">sucC</name>
        <name evidence="9" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076588.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72275at2157"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="313"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="381" mass="41027" checksum="38A8A170D3513B54" modified="2014-02-19" version="1">MKLHEYQAKSIFADAGIPIPDSRLATTVDEALDAVDEIGYPAAIKAQVHVGGRGKAGGIKIATDREEAEQYAEEILGMDLKGYTVDSVLVEEGVDFVDELYVGVTMDRGEGKPVLMVSTEGGVNIEEVAEENPDAIAREHVDPAFGLHPYQARKVVYEAGVDADVALDVASILSTLYDLYEDSDASEIEVNPVMITSDRDVVAADAVMNIDEDALFRQPELAEMAEESYEDDLERKAGEYGFDYVRLSGNVGIIGNGAGLVMTTLDLVDYYGGSPANFLDIGGGAKAERVTQALDMVFSDENVDAVVFNIFGGITRGDEVAKGINEALEGFDEIPKKVVVRLAGTNAEEGMEILNTDLVEVEKTLEDAVQRAVKNAEEVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRK4</accession>
    <name>V6DRK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076009.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10748" checksum="EB18F1DBB29CF475" modified="2014-02-19" version="1">MNGTTYQQAEQDVYYVHGIIEISDDAAQRGGFIDEFDDAHTVEQSRPRVFDIGYHVVAPTSNEAYRRAANLIHAKAAVGGYSGEYNLGSLLPRIAATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN0</accession>
    <name>V6DVN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5966" checksum="82DB86C93F03F6D6" modified="2014-02-19" version="1">MADEWRGGAGRLTPIRSACGFLHKNSLLSFSEKAFQEKPQDLETVSRAPTPCET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN1</accession>
    <name>V6DVN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8232" checksum="5E15CF9108184904" modified="2014-02-19" version="1">MRVADDPVTPKRRCVNWTRDRAAYRVRGRCHRHTVVTRLTLSSVLYPTGSVYPTSGVLSLRAIAFDCSSVTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN3</accession>
    <name>V6DVN3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C469_13070</name>
        <name evidence="9" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077012.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43299at2157"/>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="8">
        <location>
            <begin position="5"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="308" mass="34749" checksum="1D31C11098D849F6" modified="2014-02-19" version="1">MSRILVTGAAGFLGSFLCDRLLADGHEVIGMDNQVSGRTENLDDAFYHDDFSYYEHDVTEFIHVSGELDAVLHLASLASPVFYRDHPIKTLKVGALGTHKTLGLAKEKDATYLFTSTSEVYGDPEVNPQPESYRGNVDSYGPRSCYDESKRYGESLVRAYRDQHDLDVRVARIFNTYGPRMRLDDGRVIPNFMKQALTGEDLTVYGDGEQTRSFCYVSDMIDGLVALLESDVQEPVNIGNPDERTINELAEVVREVTESESGITHKELPPQDPQVRRPDITKAREELEWEPTVDLRDGLRRSVPYFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN4</accession>
    <name>V6DVN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6421" checksum="F74930C9CF27321D" modified="2014-02-19" version="1">MKNANASLGVAAGPRREVDDEDERVLAVGVVAADPPDRVEPLVGVQRPGGVVPLVVGGKAHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN5</accession>
    <name>V6DVN5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C469_13050</name>
        <name evidence="6" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077014.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58376at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="50"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="304"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="394" mass="43267" checksum="D643E8BD930DC457" modified="2014-02-19" version="1">MADFSFTPNDAIFENREALLEEWTPDSLVGRDEELTRYHAALQPVINNETPSNVFLYGKSGVGKTAATRYLLRTLEGDATDVPELELTTIEVNCDGLNTSYQVAVKLVNELREPGRQISNTGYPQASVYEFLFDELDTCGGTVLIVLDEVDHIGDDSLLYKLPRARSNGDISDAKLGVIGISNDLDFRTQLSSKVRSSLCEKEVSFSAYDADELRLVLEQRERVAFQDGVLEDGVIAMCAAYGAKDSGDARKALDLLLEAGDVARESGSDVVTEAHVQEARERVQMDQVVEGIQNYSEHGKLVLYALTLLHERGETPARTREVVETYREVAHSEGVSPVSERSVRDYLGELAQLGITSSTEHNRGKGGGKYNEHRLAQSVSAVRSGLSTLLESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN6</accession>
    <name>V6DVN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">L593_08240</name>
        <name evidence="1" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077736.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126705at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8681" checksum="206B67CD6F13A9AF" modified="2014-02-19" version="1">MPSITVNVDDDLKARMERHPEINWSEVTRQAIEEKIEALEVLDELAGESELTETDVREIADKINESGRKRVDEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN7</accession>
    <name>V6DVN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4588" checksum="B0B7691CBFFEE423" modified="2014-02-19" version="1">MVPPEDDASPELVIDDVAESLTNEGHDVYRGREFITIREDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN8</accession>
    <name>V6DVN8_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077737.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="135419at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="248" mass="27011" checksum="0B48DC3EA61E015D" modified="2014-02-19" version="1">MSKPKQTDDLDPRSVDLAKFIQDRSALLVVMGVFAAVAVYITQAAPTIGTSTNPELMYAIGFVSALGMTLLLLYLVYKELAVEAGSWHNLHRAHYRLDNLRLALFSLFNAMLVLSISFLITRYEPVIFILVLVATLFAGGGIVLRLLYYVGGLLPESAWARIPAIFTLSLVTMLISTFVITEYLAGIEISTIHEMSLTEPVPVAIGVAYILVISIRSVAALGVLASFASIPLVAFDKIRGTSPYDNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVN9</accession>
    <name>V6DVN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5147" checksum="46DA536AA4E0B101" modified="2014-02-19" version="1">MKVTVVKETLSLINIDAVGPDIQTNNTLAPHRPTPESTSSPSHLPHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP0</accession>
    <name>V6DVP0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pilin_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C462_14840</name>
        <name evidence="3" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012859">
        <property type="entry name" value="Pilin_N_archaeal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07790">
        <property type="entry name" value="Pilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Pilin_N" evidence="2">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="13768" checksum="D0176063AF2D8D6C" modified="2014-02-19" version="1">MSPVIGVILMVAITVILAAVIGTFVLGLGDQLGDTAPQASFTIDDNSTQTINITKTGGQSLDAGDLVLSVDGERVNSSFPGDTWETGERKEITKVDDAESPADWNSGEATVRIIHDPSGNAIFERTWDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP1</accession>
    <name>V6DVP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_14230</name>
        <name evidence="3" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077766.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110514at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="78"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="15431" checksum="889ABC0D47EAB1C0" modified="2014-02-19" version="1">MIEIPDSLRSVFSAQLEERDGSYVVDIPTSEIEHDALVVDETYRVAILASESSTGQKTQQEQHQSTAQETTPTSDDPPVDEGEVRDVTIETTGDQSDGIAKVERGYVVIVSGGQPGDEPTVEIEQVQANVAFASIVKPDSRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP2</accession>
    <name>V6DVP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06679</name>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="13740" checksum="F4813A3DD49011DD" modified="2014-02-19" version="1">MAAERSGRVTDDSAPDDRPEVPTVSCARCDREWDLDRELDEIPPGGHAIEQFALDHERHTGHYPDDVTPWTVRCRRCPDGERFLSERPARRWAETHARHTRHTVDIEAPTGDDGVVTASDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP3</accession>
    <name>V6DVP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C462_07865</name>
        <name evidence="3" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="354" mass="37264" checksum="5955E272AFDF7534" modified="2014-02-19" version="1">MSVESSLDEPVVGESVTFNVTVTNQAGSGGVVDVSSIMLRTNEEHYERIEDVGSLAPGGSLTVQMTTTFEEAGQKNLRAHVSAGRQSGGNLRAYYTPVTVDVQELDINGGLSTTTNDSDETTVTFTNYGNVKLSDVEIAAATDDEVRDRRNALDVGPAEADSVTFETDNYETDTVTFTVAYTARGERYETTRTVTLNRQVTGEIRLTGLEVTETGAATSIEGEAANIGGTDVESVLVSIPDTDGISPVGGSGEYFVGSVDASEFATFELTANVESDTVPIEIAYIVDNNRVTTTQTIDVSSITTTTGAAAQNQPEATADGDRQGSSGLPVIPIVVGVLLIVSLGAAGLYLWNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP4</accession>
    <name>V6DVP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4082" checksum="012770D694B0CD26" modified="2014-02-19" version="1">MTRRDSVGSGRRSRQYISGCSSNENSCPITVGGAHAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP6</accession>
    <name>V6DVP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C436_08509</name>
        <name evidence="2" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077019.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61185at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04189">
        <property type="entry name" value="G1P_TT_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005908">
        <property type="entry name" value="G1P_thy_trans_l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01208">
        <property type="entry name" value="rmlA_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="357" mass="37581" checksum="9EA263883BC89E5E" modified="2014-02-19" version="1">MKGVLLSGGTGSRLRPITHTGPKQLVPVANKPVLEYAIEDLKTAGITEIGIILGNKGRDAIQDLLGDGSKYGVDITYIVQGNPLGLAHAAGCARDFVGDDDFVMYLGDNILKSGVTELVESFEAGDYGAGIALQEVDDPQAFGIADVDADGNVTELIEKPDDPPTNLALIGMYVFSPAVFDAIDELEPSWRGELEITDAIQSLLEDGHAIDSHVVTGWWKDTGKPEDILEANRLVLEDEALDTAGTIEDGAETDGRIELAESATIEAGAVVRGPVSIAADTTIKAGTYVGPYTSIGASCTLENIHIENSVVIGDSTITASGRIVDSLLGRSANVESAEKLLPEGRRLVVGENSQLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP7</accession>
    <name>V6DVP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_10842</name>
        <name evidence="1" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="6053" checksum="C4B7EBC49CC377DC" modified="2014-02-19" version="1">MLPRLRVADAFERVAERRGIEPETGDWSTWFEVQPPLGDRIARLRERAGDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP8</accession>
    <name>V6DVP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1494</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="15481" checksum="E543731BFBDCA422" modified="2014-02-19" version="1">MIRLHGQKFWLYGAVDPYTNEILHVSLYSTATKQTTRWFLTELHQRYQLDDVEFLVDAADYLGPVLAEDGYRFRVIRHGNRNAIERVFWEIERRTSSFANISSHVALETTQNWLEAFAVYQIHAKVNGMLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVP9</accession>
    <name>V6DVP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="459" mass="50535" checksum="518F6CE7A297C7AA" modified="2014-02-19" version="1">MRFEVGGEPRLDLLAVAQQFPVLVRVGAVADHPAVPHVVVLRAAGATEHLEHVQRRDVGLALQRVVVLRVADDDAAGGEVHPPRERRRREEELDLPLLEPLLNAVAVVLPEAGVVEADAVGHRLAERVVREFLRLVVEVVVVPRVDGDVALGDLVARLLGRLNRVLSRGDEHERLPVLADVRLCQVQRAVEPAVLVGERVRPVRVRLYARLQIDRAVLVAERVGRLRGRVEPLGDIVDVRHRRGERDDAGVLKPAEPRDGDLQHRAALLGVEQVDLVDDDAVHVGDKGVARGVVFPRRAVGLLRGRHQHVRALGAARVQVALAGDDVHGVAHVLEPLPLALLLVGERAQRRDEEGRSALREGLTDGEFGERRLPGGRRGRRDDVAVGLQDARQRLALHPVELLEPEGVGELRHRVRDLHGTPHPCASRREPRLCRIGSRGGLRGQRRFSCEPSPQTHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ0</accession>
    <name>V6DVQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferases group 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C468_00730</name>
        <name evidence="3" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="30"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="210"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="356" mass="40180" checksum="FFA2742852ABA16A" modified="2014-02-19" version="1">MTIDICDVIKSIDKNNKKVALCSFTLTEGDGVTQVIRQQSNSLVEAGYDVTVFSLNIDTDFNSKVETVSYSWDQTTYSGRLFRLLFFLFPAFLKSIHSLSEFDVVVTHRYPFTLSGYIASKISDVDYVFWSHPSQEPPKDISVVSRIWLHTLKYLETSHFSIKGADVICTVSEQSKEYIKKYVHQDITVIHNKANMDRFKNPASREEVCSQLDLDKNVTVAIYVGRITEKKNINTLIDVFESNVSDEDTQLLLVGKKTMPKYTSRLERQSSSRVKFTGFVSDEVLAQLYSMSDVFVTCSMEEGWGLPISEADQFGLPIIAFETHPAAQHISDAITVPQGDNEKFGQHLSNVLDGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ1</accession>
    <name>V6DVQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C436_21620</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="70"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="24725" checksum="1279384E45A37098" modified="2014-02-19" version="1">MSNCFRVEETHSYRETPNRLKYMAEVRDALDLDQDDLPDHTTIYKSFDRLKMWVWRALLRVSAQQHPQSGHVALDSTFFDRRRASLYFRQRAGRTIQTLKATTLTDVESIAVLDVHIAARWKHDTKTGPQVVAADNGFQDWHTEYEIAAHDVEYLVHYRGSSAKAAANNALNRANGYAQRWMAETSYSTTKRSLGDAVRALAGIDSSVKLSSCSPLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ2</accession>
    <name>V6DVQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6666" checksum="DEAE34AF72DFDE28" modified="2014-02-19" version="1">MELNTEFHQRFGVASRSTNTKLVSSKQPLKRSFSGIYNFENIPPHFSNLIRTPPPLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ3</accession>
    <name>V6DVQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5641" checksum="C344580AAF661090" modified="2014-02-19" version="1">MTTTPKWTGNRQFLELIQLNELRRLIQTRLSLLRLKQGLSSQTLKTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ4</accession>
    <name>V6DVQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3982" checksum="427329EBDFDA0C30" modified="2014-02-19" version="1">MSGRGSAGRMSVRTALQEQTVRPLLSEPSFVAATLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ5</accession>
    <name>V6DVQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferases group 1 family protein</fullName>
            <ecNumber evidence="2">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DDD_0388</name>
        <name evidence="2" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.57" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="174"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="355" mass="40465" checksum="2B11FEDA72DE96AA" modified="2014-02-19" version="1">MLPDEIDVLHKYGMERHYSPIKDLSVEFGFNLRFYEYTFFNGREINIFSSSARLPALKDDVLENLSFLFLSSVQSDTFPIIVGAEPFDIRLCYIYPALKNRNIIYHTSWPDFSSPPHNVGKLVELLWHRFLSRADIVTVTKTSKRSIENLGYSAEYIPHGVDCDMYRPLPIAESNQFTILFVGRFVHEKGIKILLDFAKTANMSDFKIKFVGEGPLSDDISQMEEEYPVENCGYIQDDSELARIYNKSDVLVLPSIISQKTGWQELFGIVLIEAMACGTPVIATSHTGPSEIISHRENGFLLEEPNVDELYEYIAMLKNNKSLADSLGKEGRKAVLNKYSSDSVSKKWKQALEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ6</accession>
    <name>V6DVQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08725</name>
        <name evidence="1" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5853" checksum="B226B3C472AEDEB7" modified="2014-02-19" version="1">MTPNNPETVRGTCSFCGETVTDRHAIIEYETASGQPGVWAECPGCGEIVDPINAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ7</accession>
    <name>V6DVQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4466" checksum="C820AD3DF5CA25D9" modified="2014-02-19" version="1">MLEYNPARNKDNDREALDLTIDGVVANTATWDGDYYVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ8</accession>
    <name>V6DVQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_13145</name>
        <name evidence="2" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9429" checksum="C9F1240FE61959B8" modified="2014-02-19" version="1">MCFAGRLIAHTNVDRLLEAFDRVAADTDATLGIVGDGPERDALKAQADALTHADRVEFLGFLDDYEDVCGHMRAADVFASPSTREGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVQ9</accession>
    <name>V6DVQ9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NJ7G_4091</name>
        <name evidence="3" type="ORF">BN903_122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077028.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107911at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="12451" checksum="6FA25EEC398801B3" modified="2014-02-19" version="1">MPIDIDRFEEGPTEELRAGGRTNGERILGFLASSPDQAYTPKEIHEATDIARGSVGVVLSRLEDRGLVRHRGDYWAIADDQAVEKTITAMATARAATERLGPEDPDDWGPGMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS0</accession>
    <name>V6DVS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9188" checksum="942DF07A39EBD6EA" modified="2014-02-19" version="1">MPLERSRPDRGASDTAATATPIDHGCRPAIGLSIDQPRALVPASAARIQRSAVVTQLCHPFPTELLRMESRMKLSESGIELRSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS5</accession>
    <name>V6DVS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15599</name>
        <name evidence="1" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077786.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99069at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="122" mass="13909" checksum="97BA5CD0DEC00777" modified="2014-02-19" version="1">MPVPVDELTADEPFPVKPESNEYKALSFLVTHYEYGFTPREIVARTALDKTTASNVMARLFETGLVKRVDDVYHIEPRQVDELKYRLESLDSAVRLFEATPNDDSYAEEGWEQEVPSIDPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS6</accession>
    <name>V6DVS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase ISH18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_05186</name>
        <name evidence="1" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="13718" checksum="2B2E5700ED29EFF0" modified="2014-02-19" version="1">MTILGVSYYTALTIYAELGGIDRFDGDKEVVSYVGLNPVIRGSGDSRIEGSISKRGSGRVRWLLVQAANTAVHTSNDEYLSRFYDRLASRKNSQKAIVAAARKMLVSIYHMLDRGEAYDPPGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS7</accession>
    <name>V6DVS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_10180</name>
        <name evidence="2" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="179" mass="20855" checksum="34873D3159128DD2" modified="2014-02-19" version="1">MTGGESSPEGPMERQPTGEDRVRMIARQISEPRTANWIASETDWSHEPTKRALERLVDNGVLHRDDTGAHTTYFPDYRRQALNEAVRLRDSGHTVEDLIERLTEMNAQIRRWEAEFDVESPNQLRGTIADQRLDVTEENRRRGIAREWEQLRQRIEIVGFVIREWDFLAPATECGESLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVS8</accession>
    <name>V6DVS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077777.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7491" checksum="4AF6557F1941750E" modified="2014-02-19" version="1">MTIPQREAGFNLVDAIAPSQLPTSGDERYEIRGIDEPAGEVSLTLGAHQSASDVLDRIERTLGETPREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW05</accession>
    <name>V6DW05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-acetylhomoserine/O-acetylserine sulfhydrylase</fullName>
            <ecNumber evidence="4">2.5.1.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_06345</name>
        <name evidence="4" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.49" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077902.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40508at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="445" mass="47606" checksum="85927FB05D1E2541" modified="2014-02-19" version="1">MTRGFSTRSLHAGAEPDSATGARATPIHQTTSYVFDDADTAAEMYALRAEGHIYSRLSNPTVNVLEDRLADLSGGSDAVATGSGMAAFDAITTVLASAGDNVVASSEMYGGTAAYLTSIAGRRGIEARLVDTLDYEAYADAIDGDTAFVHVETIANPSLVTPDFERLADIAHDHAVPLVVDNTFATPYLCRPFEHGADITWESTTKWITGNGTTVGGVVVDSGQFPWDHPDADYDELDGESPAFPIDFVEQFGDAAFANVVRQRGVRPTGGQQSPFDAWQTIQGLNTLPLRMERHCENARRVAEFLRDDDRVDWVSYPRFEDHQSHGNAAEYLDGFGGMVTFGVDGGYEAAKTFCESVELTSFLANIGDAKTLVIHPSSTTHAQMDEEQQRLAGVYPEMLRLSIGIEDPEDVIADLDAGLAAGERAADGESVDEGSADGSDGEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW06</accession>
    <name>V6DW06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6031" checksum="84837E76D625EA48" modified="2014-02-19" version="1">MLRTTDSLARCSSRSPSATARRHAPPPSFISNHGIAAPLVGASGLRGVSPLRFVPTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW07</accession>
    <name>V6DW07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3495</name>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077126.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="135637at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12534" checksum="AFF3E99283E3271C" modified="2014-02-19" version="1">MMTSQIEAQIPPLVQIKDAVTAGYAVSLYIAERDKGPHGKRLAVLEIDPDYRVECVLNLQDFGFQEQTMEAMYTVPIEGTPLMVDLGEIESESVLREFLSCLGVRENRSKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW08</accession>
    <name>V6DW08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06185</name>
        <name evidence="1" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4785" checksum="9C79EFC6ECE61211" modified="2014-02-19" version="1">MSDGTADDGGRPCPVCETPMYHRHCKYVCPAHGVVYDCSDTFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW11</accession>
    <name>V6DW11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="5997" checksum="B795401A90D255FE" modified="2014-02-19" version="1">MVVRRSIRSQSVVFAVAGPSQARCLGRRVIAADTRSRGFISGLGTKSVWNSSRGCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW12</accession>
    <name>V6DW12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphonate ABC transporter, permease protein PhnE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnE</name>
        <name evidence="6" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077925.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="73"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="264" mass="28037" checksum="5F8080D1DF778140" modified="2014-02-19" version="1">MAGAASDWSRFDARERLFRIGSVVVAAAIVVGSWEWLDMSLRYVGSAPLQVSDLLGRMYPPDWGYLPNAVGPLAETIQIAVVGTIGAVLMAAPVAYISAENTTPNKATYALGKLIVTVSRSVHTIVWALLFVVMFGPGALAGTVATAVRSIGFLAKLLGEEIEEIDFGQVEGVRATGANPFKLLVYGIVPQIKPALVGISVYRWDINVRAATILGFVGAGGIGVQLFQAINSFAWRTVSALLFAILAVVIVSEGISAYARKKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW13</accession>
    <name>V6DW13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="10122" checksum="3BA726C800E152FD" modified="2014-02-19" version="1">MVFRRDPVRDTRAVFSTASKISETKDFNKARNQNVNFTLGLRSVSTTQDMGLVPHMGFWLVRISDPGHLSHGGSGSTHKDSLDSQGKPRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW14</accession>
    <name>V6DW14_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C469_15303</name>
        <name evidence="6" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Archaeal flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the archaeal flagellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077910.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="94462at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097589">
        <property type="term" value="C:archaeal-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35903">
        <property type="entry name" value="PTHR35903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01917">
        <property type="entry name" value="Arch_flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0974">Archaeal flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="237" mass="24307" checksum="64A5830640E13F96" modified="2014-02-19" version="1">MFEFINDREDRGQVGIGTLIVFIAMVLVAAIAAGVLINTAGFLQSQAEATGQESTDLVSERIDVTSEVGIVGNNSTGELKSVNVTVSGAAGADQIDLSESTIQAVGPNGQANLVFTDTPASGSGDIGNASQLNASEFAVLDSDGGFVDSGNAVLDDDTDYTIVVNPGAEPFGDMTNDDIYNASGSNEYTYAHTDSSLSAFGEGESSSLEIVSPSSATTSVELNAPDLFTEDGEAVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW15</accession>
    <name>V6DW15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="9">1.3.8.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C467_10581</name>
        <name evidence="9" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.1" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077934.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36092at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004085">
        <property type="term" value="F:butyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="128"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="241"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="392" mass="42182" checksum="590E8F4A1EBC2442" modified="2014-02-19" version="1">MTGVRVGSALTDEQAAVRDLVREFAAEEVRPTAAEADETETFPEDVWDGLAELGLTGLTVPEEYGGFGADETTYAVANEALAHGSLAVATALSVHCLATSCIAEFGTESQRERWLPEMAETGRPVGMFCLSEPQAGSNPAQMSTTATYDPDTDEYALNGEKQWITNGQRGGVAVVFAKTVREESDTNEADDAITQFLVPADTDGFEVGKKEEKLGLRASDTTGITFDDCRIPAKNRLTEPGGGLSAAFRTLTEGRIGIAAQAVGVAQAALDEAKSYAEEREQFDRPIADIQTIRHKVAEMATDVSAARLLVREACRQAEAGEDYRVAASKAKYRASEAAMSVTNEAVQIHGGYGYTTEFDVERLYRDAKITEIYEGTTEIQKTIVARGVFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW17</accession>
    <name>V6DW17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD superfamily (Subfamily IA) hydrolase, TIGR01548 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04271</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077953.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46460at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006438">
        <property type="entry name" value="HAD-SF_TIGR01548"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01548">
        <property type="entry name" value="HAD-SF-IA-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="287" mass="31531" checksum="37E891F4C8387386" modified="2014-02-19" version="1">MQVDAVVLDIDGVLVDVADSYRRAILESVDRVCGKPIDPAAIQAFKDAGGFNNDWELTDAAALFVIARREGLRMDIDEFTDRVRELGGGLDAAKDVVGDLPRVAQARVRDQWDRDALRETFQALYLGSELYRELEGGEPPVETEGYIHDEPTLVDPETIADLTARFDVGVLTGRPAAEADIALERVGFDVPDDRRFTMDDWEEGKPHPRALVELAERFDAERVAFAGDTLDDVRTARNADESDATRVYYGIGVLTGGLTGESGREKFAESGADAVVEDVNELVDLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW18</accession>
    <name>V6DW18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7604" checksum="9E66DCAFD173EEAC" modified="2014-02-19" version="1">MEDFNRAIFFKYGSMALLKSSDSDMFGSPCGQYRRLTDRSIQGTHRSLNTIPKNLISRINKMRSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW19</accession>
    <name>V6DW19_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription initiation factor IIB</fullName>
            <shortName evidence="5">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C469_07141</name>
        <name evidence="5" type="synonym">tfb</name>
        <name evidence="8" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077959.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35979at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="1" evidence="5">
        <location>
            <begin position="150"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="7">
        <location>
            <begin position="150"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="5">
        <location>
            <begin position="244"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="7">
        <location>
            <begin position="244"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="43"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="37666" checksum="5A2F838720753B3B" modified="2014-02-19" version="1">MTRPTRQRDHDRQRVGDGDAEEAEFDVEDVEDVDELDPEDFDPEDLTRTADGELIHEETGLVIEDEQIDPGPEWRAFNHNERQEKSRVGAPTTKTMHDKGLTTTIDWKDKDAYGRSISSKKRSQMHRLRKWQERIRTKDAGERNLQFALSEIDRMASALGVPRSVREVASVIYRRALNEDLIRGRSIEGVSTAALYAACRKEGIPRSLEEISEVSRVDRKEIGRTYRYISQELGLEMRPVDPKKYVPRFSSELELSEEVQSKANEIIETTAEQGLLSGKSPTGYAAAAIYAASLLCNEKKTQREVADVAQVTEVTIRNRYQEQIEAMGIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW20</accession>
    <name>V6DW20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_05944</name>
        <name evidence="6" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077138.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62488at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="265" mass="27775" checksum="0692332E8464E0BB" modified="2014-02-19" version="1">MVALDAYLFVFVAGLITALATGVGALPFFFFETISDRGNVALWGFASGIMISASLFGLVQEGLAEGTPVEIAVGMLAGVVLVVVAHDVLTDAEIDPQEYAEADFKKLILILGVLTVHSFPEGIAVGVSFADLGLEGGTVLFGFTVPLLAVFMTLAISIHNVPEGTAISIPLRAMGVSKWKMVWWAVFSSLPQPIGAVVAFAFVRYARAFLPYGFGFAAGAMIYLVLSEFVPEALETGADLPRGGKPILVGGMALGVALMVPLAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW21</accession>
    <name>V6DW21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="10574" checksum="D82D810A56E7B049" modified="2014-02-19" version="1">MLPLASSPAAKPPAARGAPRHAARGNVQNRTSYLPSLVSRRRSAPATDSLAGWLAAAEGGRSQARHCDGRMFPANEDHDLTRFGAYSRAWPPKNPNSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW22</accession>
    <name>V6DW22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_12867</name>
        <name evidence="1" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077143.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99949at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007561">
        <property type="entry name" value="Cell_div_SepF/SepF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038594">
        <property type="entry name" value="SepF-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04472">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="12677" checksum="7303792D36A5EC31" modified="2014-02-19" version="1">MGIMSKILGGGGSRSVDDYVELDTDDFADAHAETGTQVHFAEIGDQSDVIPIKDAVYDGDFVIADITRHSTSDRTIEHVYDELRQVVQEVDGDIVQKGDDQIIVTPTGVKVSRQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW23</accession>
    <name>V6DW23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_09176</name>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6250" checksum="3A60728374153E96" modified="2014-02-19" version="1">MGVVPTTMTPSPTHTFVCPECRRSIEVDDAMRATLLEAGCVVCGAPVTEEDIGEAPAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW25</accession>
    <name>V6DW25_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06255</name>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077912.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108228at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42200">
        <property type="entry name" value="PTHR42200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01917">
        <property type="entry name" value="Arch_flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="16904" checksum="7CB7B64B74DC5CCA" modified="2014-02-19" version="1">MASVPVSHLILFIASLVIAAGVVGTITTGVDRVSAAVEDAGLDATETLRTDVTIISDPSAGVYNASENNVTLLIKNTGTYRLAPDGSDLDVVFDGSYVGPDATSGELVSADGANAWSRGDVLRLTINVSEIEGSGGTLDDGDHRVFLSANGDEELFQFRVEGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW26</accession>
    <name>V6DW26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7099" checksum="5B2198D56D8A0D63" modified="2014-02-19" version="1">MDRNTYMGAAAYMRLGSDPLRRLGAVFRVGTCPVVCVPARSTRSQSGGYASVSSSSAATAASLPSRTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW27</accession>
    <name>V6DW27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase superfamily protein</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_05849</name>
        <name evidence="3" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="65"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="249" mass="27164" checksum="5B78B827B680F8FA" modified="2014-02-19" version="1">MSRTRHRRATPGEPGPTPRDPPRAHEATRRRVRRGGPGREGGRHGRPRPRXXXXXXXDRPRRGLADRVAIFDWDVHHGNGTQDIFYDRGDVFYASIHEDGLYPDTGALDETGEGDGAGTTANLPLAAGAGDADYLYAVDEAIAPAVDRFDPDLLLVSAGFDAHRHDPISRMRVSSEGYALLTDRIRTLASDVDAADAYVLEGGYGLDTLAEGVSMVHETYDGRTPVATDEEPDEKTESLVADLRSELDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW28</accession>
    <name>V6DW28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06235</name>
        <name evidence="1" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8004" checksum="BE30035796B723F3" modified="2014-02-19" version="1">MNCVAADNALGRPLLDLLREAYDGVPDDCTVDEGDDRGVYAIDKADRLFGWTPSRSWRDAADEEIAEPTLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW29</accession>
    <name>V6DW29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7071" checksum="109B9DD00DC7B47C" modified="2014-02-19" version="1">MGFSESVKRLRSPLCVPTTDRVTSVRTDLRRSGGGDEGDAADDAVDRAHARLTGSVDPTRREEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW40</accession>
    <name>V6DW40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C464_01796</name>
        <name evidence="5" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040087">
        <property type="entry name" value="MJ0021-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43288:SF1">
        <property type="entry name" value="PTHR43288:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="128" mass="14509" checksum="F01B324162AF506C" modified="2014-02-19" version="1">MISKGCEQCAKGGKMVLFVYGYCDQRDCFYCPLGENRKNVTDVYANERKVESDEDVIEEAKRMSALGTSITGGEPQEAMAKTTRYLELLKDEFGEDHHTHLYTGITGGRENMRRLSEAGLDEIRFTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW45</accession>
    <name>V6DW45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="14655" checksum="C93764067547C00D" modified="2014-02-19" version="1">MPDVDDENSIDAGAVNTSEAPGARLHLTVFVEDGFTTETAEAPVARTRCARCGPRRSRCSLLQSLRRASSPSRLPLRVPPHTATAPHASPASSLAVFASLDRRRLPRAVLLAVAEGDRSEARATALSSADQSLRHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW46</accession>
    <name>V6DW46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_09121</name>
        <name evidence="8" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="13851" checksum="17B3A964295E3145" modified="2014-02-19" version="1">MLSKLLRFAGPLATAGTLAILVGYVTLIGLFFGPVASAASRQPPARELFYTKTRNLALFAFGVLIAWAMLQIAGLFDAFTATVTLEYLDILLRVGFAGFVFANVETLTADAESAAGDKEGGSVAPAGTGASTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW47</accession>
    <name>V6DW47_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">rnz</name>
        <name evidence="11" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077165.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111803at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02651">
        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="10">
        <location>
            <begin position="20"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK39553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="309" mass="33469" checksum="5B04B5A09AFCC089" modified="2014-02-19" version="1">MSLRVTFLGTGGAVPTVERAASAVFVNREGDRFLFDCGEGTQREMMRSGTGFAVDRIFVSHLHGDHVLGIPGLVQTLGFNDRTDPLTIHCPPGTADHLRDLVRAVGHDPAFPVRIDPVAPGEVAYETDEYAVRAFETEHRTKSQGYVLAEADRPGRFDRPKAEELGVPVGPKFGRLHEGESVEAEDGTVVDPEQVVGPPRPGRKLVYTADTRPRESTVEAAADADLLIHDATFADDMADRARDTAHSTGREAGSVADRAGAKRLALVHISSRYAGDPRPIREEAREAFDGECLLPDDGDLIEVPFPDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW48</accession>
    <name>V6DW48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="393" mass="43213" checksum="2BD17D960BDBC551" modified="2014-02-19" version="1">MEVVPGDGALEVRILLVDLRSVVLDERPRRLVEGRLQVVARDDRLVLRGVEDDLAGLDQRAVREHDRQLLRVRVRDPVPHRVRPGGVVADSADDGRPRGGGRVGRELQPVLGEAVVEVVLNDAGLDHCPPVVGADLQNLVHVRGEVQHHAARPDGLSAQRGAGPPRDDRDTVVGGDFHRGLNVRDRARDHDPGRSRLIDAPVRRVQHLRVLVELDLSRDPLAEVRCQVPISGHVRPVVTERGRGRVQVRRVAPPRGFGCHSVIRGKRENKTFVNDNFARRSGSGHRRRAAVSRRDLTRLPERRVPWRYSTRVSTWPTRTGRRTGTSNSSGSSAPGSSRPRTVTRGTSTSRTTPASSFSSPTRTARSRATTATGTTTSRSTSTRRSSRSTTTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZV1</accession>
    <name>V6DZV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Copper-transporting ATPase</fullName>
            <ecNumber evidence="5">3.6.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_16459</name>
        <name evidence="5" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.4" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="224" mass="23754" checksum="90453227BBCDC1F3" modified="2014-02-19" version="1">MERLEREGKTVMLVARVRAGADDGELLGVVADADTVKPSAKEAVSQLRDRGVDVMMITGDNERTARAVAEQVGIDPDDVRAGVLPEDKSDAVESIQADGRKAMMVGDGVNDAPALAVAYVGTAIGSGTDVAIEAADVTLMRDDPLDVVKAIRVSDATLQKIRQNLVWALGYNTAMIPLASLGLLQPVLAAGAMAFSSVSVLTNSLLFRRYGPDRDYALLGFLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZV2</accession>
    <name>V6DZV2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="12">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">trpB</name>
        <name evidence="15" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the TrpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="12"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078248.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24741at2157"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 12 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="14">
        <location>
            <begin position="75"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CDK40873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="434" mass="47197" checksum="DF593AACD8DA3C1E" modified="2014-02-19" version="1">MSETDTRTTEETETARRPGRERGRDDGKFGRYGGQYVPEALMPAIEELTDAYERYVLDNEDGFVDEFRERLADFGGRPTPLQRADRLSERYDTEVYLKREDLLHGGAHKLNNALGQVLLAKYMGKERIIAETGAGQHGTATAMAAAHLDMPCTIYMGERDINRQRPNVFRMKLNGSEVKPVTTGRGTLKEAISETMRDWAETVEDTHYVIGSIVGPHPFPVMVRDFQAVISEEAREQAREKTGGLPTDVVACAGGGSNTMGSFAEFVDDESVALHAVEAGGSTLEVDEEAGVAPNSASLFAGEEGVLHGARTKLLQDSDGQIMESHSVSSGLDYAGVGPELAYLVDEGRVEPVAVDDDAALEGFHRLSNTEGIIPALETAHAFGYLEEHHDDLGERVVVNVSGRGDKDLDAAIEETDKRDIEGAPDMSMFTGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZV5</accession>
    <name>V6DZV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA topoisomerase VI subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">top6B</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040494">
        <property type="entry name" value="Top6b_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18000">
        <property type="entry name" value="Top6b_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Top6b_C" evidence="1">
        <location>
            <begin position="28"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="15020" checksum="458A6822D92682AF" modified="2014-02-19" version="1">MQQRREKQDVLGRILPEMADKVSEVTGRSRPDIDGALARIMNNVSVEREVNGETVTLVVENHSDVNEELEITDIVSTEPSDLSDGTAVDMDGEWFVQWKPEVPSGDERELTYAIDGDADFEVSVGGVETEKLTVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZV8</accession>
    <name>V6DZV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_16394</name>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078251.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60828at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="21013" checksum="99C7B1238E7DAB77" modified="2014-02-19" version="1">MAVANEGRHVAESGFVERVRHLANAANPAFAAGCFLVPLAFLAASLGLANTELLFYTHVAAGAVWFGFALIFPALIGPTLGGLDEEASAAVNTVLIPKAVFFLVGVSLTTVLSGTVLLTPEIGLGYGFGGAWSGLALGLGWGLFAFGLAVPHRLQLSAYYETLSSSPDASKLESIEQKNLVVGLFEGAVMLALIALMTGFRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZX0</accession>
    <name>V6DZX0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">purA</name>
        <name evidence="11" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078270.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35648at2157"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
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    </dbReference>
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        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="12"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="37"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="315"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="11"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="39"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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    <feature type="binding site" evidence="8">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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        <ligand>
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        <location>
            <begin position="347"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
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        <location>
            <begin position="432"/>
            <end position="434"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK40900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="449" mass="48195" checksum="E19B56B2350C0BC1" modified="2014-02-19" version="1">MTLTIVGSQLGDEGKGALVDRWGGDADVVVRYQGGDNAGHTVVEGGAEYKLSLVPSGAVRGTVGILGNGCVVNPETLFTEIDDLRERGLDPDVRVARRAHVIMPYHRVLDGIEEEVKADDDAGDAVGTTGRGIGPTYEDKAGRRGVRIADLLDPAVLREKLEYVVPQKRALVEDVYGLDLDDKQEAAFDVDALHETYAAIGERLADEGMTVNCSDYLHRRREAGDEILFEGAQGTHIDVDHGNYPFVTSSNPTAGGAAVGSGVGVTTVGDGEVVGIVKAYLSRVGEGPLPTELDGDADEETLADEIREKGGEFGTVTGRPRRIGWLDLPMLRHAARVSGFTGVAVNHVDVLAGLDELKVCTGYELDGEELDTVPTTTERWERCEPVFAELDTWEEFDSAAVAEEGYDALPAAAREYLEFVADEIDTPIYAVGVGPDREETVELTNPLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZX1</accession>
    <name>V6DZX1_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Zinc finger CDGSH-type domain protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="primary">C467_01893</name>
        <name evidence="5" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129482at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZnF_CDGSH"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZnF_CDGSH" evidence="4">
        <location>
            <begin position="13"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="CDK40893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8525" checksum="6B67B5A2ADCA4E8F" modified="2014-02-19" version="1">MTREVTHEEDGPAILDESDMGDDGKIYVCRCGLSDSKPLCDGSHNATADEEAGVVYKYEGDDADGERREVGEKADDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZX7</accession>
    <name>V6DZX7_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_03376</name>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5864" checksum="249B432824631C53" modified="2014-02-19" version="1">MRRFQRHLFADDRWVRRVDEAYGLDSRLFGLWERLLRDERRRLADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZX8</accession>
    <name>V6DZX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AsnC family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02864</name>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79103at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="69"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="17832" checksum="ED04E46859FF28F4" modified="2014-02-19" version="1">MDAEREVLDVLARNAREDIDDIAAQTGLDAAAVEAAIESLETDGVVHGYQAVVDWDRVDEGKIRAVVEINVELDRETGYEQVADRIAKFPAVDALHLVSGDYDFAVEVLGENMQDVSEFISEQVAPMPAVTQTVTHYIMETYKDGGIRFEDGDDDDRLSVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZY2</accession>
    <name>V6DZY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4326" checksum="C704031D184D9A4E" modified="2014-02-19" version="1">MRDIDPDTLMLVAGVVISLIALAELYPLWKRRKTDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZY3</accession>
    <name>V6DZY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_01943</name>
        <name evidence="1" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20410" checksum="0139F865DA6D1ABD" modified="2014-02-19" version="1">MDGRPFAEFLEDTIEYGFTRWLVEDLPFEVRGTGNEGTLRDLYDALPEVDRAEIGGTVSIELREGGEETREQRTFDLVLRDRMGHPLFVADLNDSRDPTPEGTLESLVGNGRDIAESNETFAGAFAVTESFFEPGALETASDAVGGGLFSRSKRASFVKLSRKQGFHLCLVEARDGGFHMTVPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZY6</accession>
    <name>V6DZY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Halorhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hop</name>
        <name evidence="12" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078306.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70686at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018229">
        <property type="entry name" value="Rhodopsin_retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="entry name" value="PTHR28286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00950">
        <property type="entry name" value="BACTERIAL_OPSIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00327">
        <property type="entry name" value="BACTERIAL_OPSIN_RET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK40915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="266" mass="28577" checksum="74261F096AFB258A" modified="2014-02-19" version="1">MTQTEIFEAIQADTLLASSLWINIALAGLSILAFLYMGRNLEDPRAQLIFVAAMMVPLVSISSYTGLVSGLTVSFLEMPAGHALAGQEVLTPWGRYLTWALSTPMILIALGLLAGSNMTKLFTAVVADIGMCVTGLAAALTTSSYLLRWVWYVISCAFFVVVLYILLAEWAEDAEIAGTSEIFNTLKILTVVLWLGYPIFWALGAEGLAVLDVAVTSWAYSGMDIIAKYLFAFLLLRWVVDNERTVADVAAGLGSSSRGGAAPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZY7</accession>
    <name>V6DZY7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="7">PEP synthase</shortName>
            <ecNumber evidence="7">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C467_03416</name>
        <name evidence="12" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 7">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078284.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3139at2157"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="10">
        <location>
            <begin position="16"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="9">
        <location>
            <begin position="407"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="11">
        <location>
            <begin position="504"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="316"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="475"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK40908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="802" mass="86447" checksum="42AD08355337D351" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNZ1</accession>
    <name>V6DNZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_01710</name>
        <name evidence="1" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075820.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105389at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="13968" checksum="082E06B52E06F812" modified="2014-02-19" version="1">MGTTDLTLAVSLGALDRLARPDHALEDAATWASYVGIVSSEPSYIERRRVREADYHQEFLSGPRSVAEALSAVRNNFQTERYVFVGTDETSGAVEAVPDWTYQSVADAGMAADWKLSTPSTVDRDWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNZ2</accession>
    <name>V6DNZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="8220" checksum="555F225D9E8A9388" modified="2014-02-19" version="1">MRASYSLNASRRYWFLRIRENLGSFFTELGEARSAMRDSSPCRDHQSLREDVPLATSVVDAVREQPDERAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNZ5</accession>
    <name>V6DNZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_15077</name>
        <name evidence="4" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075824.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27680at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="3">
        <location>
            <begin position="263"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK37886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="428" mass="47689" checksum="BC47BDD4F50289C4" modified="2014-02-19" version="1">MNRETIPVTVLSGNLGAGKTTVLNNLLNTRTDLDIAVLVNDMGEVNVDAERVAEHSDISEDDEDLIELSNGCICCELRGDLLDALAKLAQAREFDYLVIESTGVAEPLPVAQTLTMGFDQGDLDPTEFYEETGIEVMDYYELDTTVTVVDAHQFWTAFDSKESLMDGDTEKDLGSLLIEQIEFCDVLLLNKCDLVDEATLDEIEEMLEVLQPRAKIIRTEHGAVDPDEILDTGRFDFEEASQSAGWVRELQQPHESAEEEHGVTSFVYTSRRPFHPERFADLLDAFPANVVRSKGHFWVAGREQTALGLNVAGQSIRVGSAGDWIATLPEEERETYFEANPEFEEIWDDEWGDRGTQLVLIGTDMDHDALRGDLDAALLTDEEMDADWTAFDDRFPTWDVEDDNEPGEGTEESAETTDDSAEEVGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNZ6</accession>
    <name>V6DNZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Natgr_0406</name>
        <name evidence="1" type="ORF">BN903_164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="6087" checksum="8F794E56816C02DC" modified="2014-02-19" version="1">METETLALFEHLSFRFLNELDVFAPAKTGRTRDHEPPELMRGFLHCYYKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNZ7</accession>
    <name>V6DNZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_06847</name>
        <name evidence="1" type="ORF">BN903_157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="243" mass="25815" checksum="70E8141647B074BA" modified="2014-02-19" version="1">MIRVSEHTNTDGDRDEAALATARARLYGLLAATFDGETETTAAALDRGAFVTVADVFPIDIETADLRGDGHDADSLAIGYDNLFVVPGTHYVPPFASAHAADPSEAFESDSRYHTAGEAGELLGNPAADMAKLYAAAGFSPGRGDDIPDHVAACFEFMRALCEREATLLEGGGSESNLDAVRELQARALSQLGWIDRFEEAVASRDSVEGVFAAIARLARTFTAWDAHDVVHADEQPSETTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRC6</accession>
    <name>V6DRC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="239" mass="26304" checksum="AAAF4F465C386B3E" modified="2014-02-19" version="1">MRRDDADRAAVVGREVVAVEAVGELDARLRTLVEREVGRVPVERVEHDVFGVVTHAGALGEIRERDARELAVELAPARHAVEILSLGDGREVAELVERDGERLLDCAPHLEFERLRVPRGSPALREDGEPVGLALPRREPVVAVLAVEVREVLDGVGTGCGHEPRYGPDRRMNVAPESGVAREQPSRAIGDGDVRDSEVQILVTERRFFEISSEFSDTRICDATFICAIPQDPDSKCHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRC8</accession>
    <name>V6DRC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4646" checksum="A45CA611295862F0" modified="2014-02-19" version="1">MALLKSSAVDSFTPQSFSTGDSYHLSNCVSVYYNITILRSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRC9</accession>
    <name>V6DRC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="12141" checksum="A534B357B3F92976" modified="2014-02-19" version="1">MVGSSAPEGPRSTADNEAVVGGAAIVVGLAVALSGLLLYQASAPGGSHVSGVGLALAFAGVFAVERISGRLGLSTTTRHRVALGFGALAAALALAFLVVDYPDFSGAVAGSGGESAAAAIWFRAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRD2</accession>
    <name>V6DRD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative signal peptide protein</fullName>
            <ecNumber evidence="4">4.2.1.118</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_14927</name>
        <name evidence="4" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.118" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076540.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5963at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046565">
        <property type="term" value="F:3-dehydroshikimate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008719">
        <property type="entry name" value="N2O_reductase_NosL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05573">
        <property type="entry name" value="NosL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="NosD" evidence="3">
        <location>
            <begin position="387"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="681" mass="72102" checksum="4D01F15FD8E751C6" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRD3</accession>
    <name>V6DRD3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">S-adenosylmethionine synthase</fullName>
            <shortName evidence="14">AdoMet synthase</shortName>
            <ecNumber evidence="6 14">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">mat</name>
        <name evidence="15" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 14">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the AdoMet synthase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="6 14"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076536.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21658at2157"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00136">
        <property type="entry name" value="S_AdoMet_synth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027790">
        <property type="entry name" value="AdoMet_synthase_2_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042544">
        <property type="entry name" value="AdoMet_synthase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002795">
        <property type="entry name" value="S-AdoMet_synthetase_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36697">
        <property type="entry name" value="PTHR36697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01941">
        <property type="entry name" value="AdoMet_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 14" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14 15" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="136"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CDK38754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="400" mass="43428" checksum="F9A5803B5E97E7F1" modified="2014-02-19" version="1">MDRNIQVSRLDRQAVEDQEVEIVERKGIGHPDSICDGVAESVSRALSQLYLDRVGKVLHYNTDETQLVAGRAAPAFGGGEVVEPIYILIVGRATKEYDGEQLPVDSTALAAARDYLSEAIPELEYGTDVVIDVKLGEGSGDLQDVFGEETQQVPMANDTSFGVGHAPLTETETIVREAERALNGPYHDDHPELGPDVKIMGKREGDRIDITVAAAMVDAYVDGLDEYDDAVENVREYVDDLAREYTDREVHVDVNTADDYDEGSVYLTVTGTSAEQGDDGSVGRGNRANGLITPNRPMSMEATSGKNPVNHIGKIYNLLSTRVAESVTSEVDGIRDLQVRLLSQIGRPIDEPHVADAQIVTEDGVELGDIEDDVLAIVDRELADVTDVTRSVIEGDVSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRD5</accession>
    <name>V6DRD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="18113" checksum="88168E32C625F198" modified="2014-02-19" version="1">MAGRRQLLAHLVGVDEVPVVREPERAGLKRDRERLRAALVEAAGGRVADVTDAGAARQRFEVPLLERVADEAPLDVAVLLEPVVRDDPRGLLPAVLERVQRVVQRARGLPVFERDADDAALLSRFVAAVVPTGVHVRVGKTAVDKNPRVRGVYLSFSTINMRDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRD6</accession>
    <name>V6DRD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14942</name>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11379" checksum="C777D99086C620A8" modified="2014-02-19" version="1">MSAIDGWSVEGSLLLLAAALVAGMGTGILFVVSAVAYRRRQGAQYQLIAVAVSMLLFRSIVGTGTILGIVPMPIHHFVGHGLDFLIAAIILYTVYAYAPGSVGNDTVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRD9</accession>
    <name>V6DRD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AsnC family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_00667</name>
        <name evidence="5" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076513.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83321at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="160" mass="17931" checksum="750CB4171DF627E9" modified="2014-02-19" version="1">MDERDVRLLKAIADLGTGSPERLHEETQIPVSTIHYRLNNLREDGVIQNDLYDFDHEALGLGVTVIVEVLASYEGPYEEFADELLAVEGVTEAFFTMGETDFVVLARLSSSDTVERLISDFEAIPEVERTNSTFTIATLRDESRAPATYDLDTLIEELTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRE0</accession>
    <name>V6DRE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6099" checksum="96E2F82D6C00DCB5" modified="2014-02-19" version="1">MSTRHRTLAKFEIHTLPFGHVPNTILVRPSNASCLLRRVAYRTCRCHIPPSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRE2</accession>
    <name>V6DRE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4472" checksum="2827901794B27197" modified="2014-02-19" version="1">MERDMLPAGKSVASRITDRRWTGGTALLSQRRGLLNEAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRE4</accession>
    <name>V6DRE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="6876" checksum="6C1527F504EAEE53" modified="2014-02-19" version="1">MLADIGTVFRRELVTVRRTPGYAVLAAGLLIVLGGLVAVGGGGGPGSCRQSSIFCSRQSYSSRFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRF8</accession>
    <name>V6DRF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="10382" checksum="EE974CA1524AF048" modified="2014-02-19" version="1">MDGERYPKMTLVEPAETFEFDYWRSVVDELSLEDEFEAVTGTPFNEDYTIEISEGILIEELLEAAEQRFILNVVHHNPNPYTILLLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRG0</accession>
    <name>V6DRG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C470_00906</name>
        <name evidence="3" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076527.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128631at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="11735" checksum="56D4627A4D9A6CC1" modified="2014-02-19" version="1">MVHDPLSPSEALRTPAGAVLGGVSLFVLAYSLVIVGAIFVGLVAVGALSVGPYLWYRIFAAVDAIADGIQRLAAAKEREVDRDSRSDELVGRDTPDTRDAPAERATERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRG5</accession>
    <name>V6DRG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
            <ecNumber evidence="2">2.5.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11956</name>
        <name evidence="2" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="17"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="248" mass="26892" checksum="4A617C86C43641DD" modified="2014-02-19" version="1">MQNVDAAGLGIGDDHPPRIMGVLNVSAESPYDPSVYDDPGEAAAYVDEELIGEGADIVDVGLESANKDLDVLSAEQELDRLDTAVETLESTSGDAVWSIETRYHEVADEALSRGFDMVNDICGFADPEMPRVCREHDVAVSKMASPPDLERPGAIEDVDDIYEALSMNGITDKTILDPAFGGWSAEKTHEDDRETFHRLREFRGYGRPLLVSINRKSFLRTIAGRSTEEALPVSLAATSVVGGKAHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRG6</accession>
    <name>V6DRG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4015" checksum="D26B08406A03ED86" modified="2014-02-19" version="1">MAVGVRHATRGDRGTGRDALGSRNLSTASGIDGTRSVSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRG7</accession>
    <name>V6DRG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5097" checksum="ACBFE4C430AD8889" modified="2014-02-19" version="1">MRFLQFHEVVNDIVGGVVDDADGATDAPEENASDASGTHPIVVTWCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB0</accession>
    <name>V6DSB0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C495_07143</name>
        <name evidence="2" type="ORF">BN903_293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334875.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124564at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="18162" checksum="E21C0A108E761E6D" modified="2014-02-19" version="1">MEYSTVGVDERLFVRLQDGEELRAGIEQAASDVGAEGGWFIGFGGLRNATLWFFDQQERHYDSIHFEEPLELTFCVGNFACVDGSMFAHTHVTVADMEGNSIGGHLESAEVFVGEVYADLFDEPVDRESSATPVLDTRQWLSAEIEASPKTHPETGFTLNHTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC4</accession>
    <name>V6DSC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4282" checksum="04B339EAA9753376" modified="2014-02-19" version="1">MKRTIHVWVIDILLLKAEESRAVGVSGSQPWMPPLHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC6</accession>
    <name>V6DSC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075963.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9709" checksum="7B7220301C8932D3" modified="2014-02-19" version="1">MEANTATEASPNSTDDEDEDPRIWTEIQRGTEGVSATVYKRENGQTTTVDETWWTWAEFTGISTQDLPISRGGTTCLEAAGPDDLTPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC7</accession>
    <name>V6DSC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C444_18067</name>
        <name evidence="3" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076821.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24056at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="143"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="401" mass="44221" checksum="16F1D441575C5376" modified="2014-02-19" version="1">MARRRQIITGSASLIAVGLAGCAGNTADGTDSTSQSTSTETDTETANETEEPESTTSDSTPYTVEIEPNDSYTFEEIPETYGVGTSPFIDMGMALGIHPTATTGLERAPLKFYDLLDLGFDESQITKIASDAESGYDKENFYAADADVWLISRNNIGRYVSWDDSDFEDVESQTGPFLGTTLRFAPQSAVQDEPNPYTMYEAFEKVATVFQRQQQFEAWQSFHDDLMSTIEDGLPPKDERPTVAAIWRGVAPDSGRFRIAPLHRLGNNTKSYYRLGMRDAFEGQYPDGPVGYEELFRADPDYIGAVGALTSSTHEEFVTNVIEPFENNENGQQLSAVQNGNVVRSGGQYMGPIVDMFSTEAVAKQVYSDEFGEWPGPVGEVSESEQLFDRQRLLDIVNGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC8</accession>
    <name>V6DSC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14871" checksum="8875767B2CAD7BB0" modified="2014-02-19" version="1">MDYRKMSARDTPEPECIETSETTSPHQTDIQLVADRLARNGIEVINTEPESNPHLEVAASKDQIESIQALLEDTETDQQYRIITSEDTNSLREWPIPNTGREQLRTVFITPQSEVRFTPKQKGILRASYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC9</accession>
    <name>V6DSC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11319" checksum="71DFCCF50224CE47" modified="2014-02-19" version="1">MTGYRTGRTDTAAVPETVRDAWWFGPGENALETPVDRYDAVASVDTTTEAPAVRTSERRSPRFARRCVFRGPARFRSRDSRDSLRSSLSHYVPSLSYNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD1</accession>
    <name>V6DSD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8084" checksum="EF328468BB767477" modified="2014-02-19" version="1">MTGRSTSTASVARTRGSPPAATTASSTSSSIARANACRSSGESTSESRDFGRSVEKGTMTSIASDGALRTGIPARRCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD2</accession>
    <name>V6DSD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4693" checksum="3CEECD80618FEA3F" modified="2014-02-19" version="1">MPDNCFDLCVRTSVELSPVSVDIGPLYRVFLDWFALPKSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD4</accession>
    <name>V6DSD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related</fullName>
            <ecNumber evidence="8">3.6.3.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Hmuk_0946</name>
        <name evidence="8" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.20" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076835.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="365" mass="40506" checksum="4D738A0E13843E4B" modified="2014-02-19" version="1">MSQVQLSDVTKMYDDLRAVKGIDVTVRDGEFLVVVGPSGCGKSTTLRMVAGLETISSGEIRIGSKVVNDVRPQDRNIAMVFQNYALYPHMTVRENMSFGLRLSGEFEDAEINERVEDAAELLEIPELLDQYPKQLSGGQQQRVALGRSIVRDPDVFLMDEPLSNLDAKLRSQMRTELQRLHEELGVSTIYVTHDQTEAITMGDRIAILNDGELQQIAEPEICYSEPNNRFVAGFIGSPSMNFFEVDVESTSDGIAVQGDSFETDLDVSLPPGRYTLGVRPEDLYTANGTGRLSVTVDVVEPMGADNYLYFKPSTDGDEEIIARVDNEFRPDPGERVTLDFDVADIHFFDESGDRVSIEATAERTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD5</accession>
    <name>V6DSD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hmuk_0944</name>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076833.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14823at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="450" mass="49485" checksum="0256304F9C575AAA" modified="2014-02-19" version="1">MSIDKTTGTDESIERRKVLEAMGGGGIIALAGCLSGDSGSNDGSDGSDGSDGSDGGSSGQTIQFLTMGVGDNIQEFFEENNAQFEEEHDITLEFTSVTWDNAQQTVNNRVDGGEAPDVARWPARWIPQLVGKDELEPVDELMESEFGDRFYQGMADGCMYQGSYYGAPWAASNKCLYYNKDVFEAAGLDPENPQLDTWDDMVAAGEQIRDETDTPALGLAGAAAIETGSQYYHYHWSHGADLIDDEGLPVVNSSEGVEALTLYSDLHQEYGITQTSPLSSTRQDIRQLFESGELGMVIAHVYTGINIDAAKDNNEVDFDYGIVQVPAGPEGRYSLNTIDAVSIFAQTEVKDLAEDLLRFYFEPDRHFEYATNKGFMPTIEEVGERDYFQESSNWAPYIEAGQYARARPKISNFNEFNNRMVQAIQEALGGQKSPQKALNDAQSDLEDAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD6</accession>
    <name>V6DSD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4455" checksum="84294F378894918B" modified="2014-02-19" version="1">MLSHFPCGRPGEEDAGRYRGRGYRVVGGHQFGYLTRVSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD7</accession>
    <name>V6DSD7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carb-bd_dom_fam9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halxa_0467</name>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334921.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="52663at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16011">
        <property type="entry name" value="CBM9_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carb-bd_dom_fam9" evidence="1">
        <location>
            <begin position="27"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="219" mass="25017" checksum="344E4E908D888DC2" modified="2014-02-19" version="1">MKRTGIQRVDDSVPLVGETAGTAWERADRVSIDRFLWTQPDSRPRTTVRALYDDETLYLHYTVDDGHSHAETTTLNGPVWEDSCVEFFASPRPDISDAYLNFEVNCVGTFHLGYGTGRTNRTLATPDAAADIRVRGSIGGPTKRPRSDDKRWWVAVELPFDILSDLVGVQVRPSPRTRWRGNFYRIRKRPETFYAAWNPVEASEPDFHRPAAFGELRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD8</accession>
    <name>V6DSD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7036" checksum="00E98AA37FDFF3F9" modified="2014-02-19" version="1">MGDRDSTDIFEEREFLAKIQANYHTTIEALAEQGEPLSVVGGNHAEEIVTDAIMDAIADADSISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSD9</accession>
    <name>V6DSD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_15714</name>
        <name evidence="2" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076838.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124778at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="11100" checksum="D9E38860480510A8" modified="2014-02-19" version="1">MYDLTGFQRDLLYVIAGLEDPHGLAIKDELEDYYEKEIHHGRLYPNLDTLVEKGLVEKSQRDRRTNEYTTTRRGTREIDARSEWEQQYIDHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE0</accession>
    <name>V6DSE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="13680" checksum="EC78E74D4D0B4C3E" modified="2014-02-19" version="1">MVLRVVLPQRDPPPEPVRRPDQRRRPLRRRARDSRHRRVRPAPRRREGVRRATGRGRGRHQVRELPDDGSRVHDDAGRRPRPGGDRERRRRPRRRARRVTPFRAPGSVPRATESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE1</accession>
    <name>V6DSE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C466_15739</name>
        <name evidence="3" type="ORF">BN903_323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075983.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125987at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="80"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="15478" checksum="65C0B55AAB40DAC9" modified="2014-02-19" version="1">MVEISDSLRTLFTGVVEEQDGEYVVSIPSSEVEQGDLAVGEAHRVGLIGVEETTDVESTQPQTGERDSQAKQPADPDQQPVVEGETYEVKIESLGEKGDGIAYVDGFVLMISDVDIGERVVVRVETVLESVGFADVVKRVNPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE2</accession>
    <name>V6DSE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HalDL1DRAFT_3279</name>
        <name evidence="1" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076840.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73442at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="19884" checksum="F67121088674B1C7" modified="2014-02-19" version="1">MVDSTDPDPRITDLSSIEPENFKFRNTQFLRADGHHYDNPHDESFLEQRREIWRVRNGDIERVLEEFPTDRPLPEQCALWIHALVGKHFFPDANHRTAIVTLRKLLRDNGIKPGAWPTERVKRVRSESHDVRREIPPIHLDGLYEEDELYRVWLQFFCEVLPEEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE3</accession>
    <name>V6DSE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7836" checksum="86FA80F4385A4716" modified="2014-02-19" version="1">MSGLADGQPVPANTFGCQGLQLLLRVRSINLLSRYRVSLPPTTEVVGFRPCTGVIRTAEKRASSPGKCPGRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSE5</accession>
    <name>V6DSE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type multidrug transport system, ATPase component</fullName>
            <ecNumber evidence="6">3.6.3.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Natoc_2641</name>
        <name evidence="6" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.25" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076844.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71942at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="271" mass="29221" checksum="AC5AFC87BAADD37A" modified="2014-02-19" version="1">MTAIDITDLTKRYENTLAVDDLNLSIPEGVVYGFLGPNGAGKTTTMRMLTGLTRPSSGTGSVSGISITDRDALRTHIGYLPEEPPLYEQATAYEQLEYAAGLRDLPEEATRERIDGLLNELDLTADADTRIADYSKGMRQKTAYIQAILHKPDVVFLDEPTSGLDPRAARTLREMITDLADAGTTVFLSTHILPVVEEIADTVGILYDGELVAEGSPADLERRAETGETRSLEDAFLELTTDEFGGAGESDGEVSAADTTNQSVVEENTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK9</accession>
    <name>V6DVK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11290</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="11678" checksum="2C98E6C89F7384D1" modified="2014-02-19" version="1">MSVFPPRGGSVRSEVRSVDAAVDPKAYVCAARGPSVANALLSRLGDYYDPDPRATVVCLFGSAFTLAMMLPIADLANQYHTFGVFGTTLALLGSVATLADLLRRRETPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL0</accession>
    <name>V6DVL0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="5">OTCase</shortName>
            <ecNumber evidence="3 5">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argF</name>
        <name evidence="9" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 5"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077710.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43727at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="147"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="222"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="256"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="299" mass="32058" checksum="9E56A68E9DA99448" modified="2014-02-19" version="1">MTLATDDFLDIDDVTPTELDALLDRAAAMKAGETDPRLGDATLGMIFEKPSTRTRVSFETGMTRLGGHAMFLGPDDIQLGHGEPLKDTARVLGRYVDGVMARLFDHEDVETLAEYADCPVINGLTDEAHPCQTLADLLTIRETVGEDATVAWVGDGNNVGQSFVVGAAMAGIDVTVASPADYGMDPDVFDRAAAFGADVTPTTDPEAVVDGADVVYTDVWISMGQEDERDEKLAAFDGFQVNADLLAGTDAKVMHCLPAHRGEEITDDVLESDRALVWDQAENRMHAQNALLVELLGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL1</accession>
    <name>V6DVL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11039</name>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076996.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115126at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="13185" checksum="05E22B4B56A9ADC7" modified="2014-02-19" version="1">MEYQPGVCNIGPTQQRRRLLLGVGSLALAAVYVAAVVALAWPQWSLALSVFPLYGAAMGWLQYRERFCIGFAGIGVFDVGEGTSEIRNEEALAADRKKAVTLNAKAVGIGVVGTVAVYGASLVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL2</accession>
    <name>V6DVL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4615" checksum="E8ED78AD97A90806" modified="2014-02-19" version="1">MTAAARLDAGLLRDRRALRPRRDVRPPRPASGAARRRGPSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL3</accession>
    <name>V6DVL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6739" checksum="6583A9BCD3CF2EAE" modified="2014-02-19" version="1">MLVILIPVESVWSDTVHAAKLTYAVRPSLEQHDCGQTHRTDVDSGSDNPTQLVTFETANDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL4</accession>
    <name>V6DVL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12222" checksum="A1EA8DECF671BF9A" modified="2014-02-19" version="1">MSVGETPACPNLFFGGLAGVVTYSTMISNYFRIHKLTALEIFTIRSRCRRQISSVHFATHRETTVKESSKMPESHSATGLLSFLSLNTSESSPTKFSVSHEPCDRFFGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL5</accession>
    <name>V6DVL5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">DNA repair and recombination protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">radA</name>
        <name evidence="9" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the eukaryotic RecA-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077714.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="30130at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01123">
        <property type="entry name" value="Rad51_DMC1_radA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00348">
        <property type="entry name" value="RadA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="DNA_recomb/repair_Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011938">
        <property type="entry name" value="DNA_recomb/repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033925">
        <property type="entry name" value="Rad51_DMC1_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02236">
        <property type="entry name" value="recomb_radA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="78"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="8">
        <location>
            <begin position="283"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="343" mass="37456" checksum="3611C7B2A60155DF" modified="2014-02-19" version="1">MPEDELEDLPGVGPATADKLVDNGFESYQSIAVASPGEMSNTADIGESSASDIINAAREAADVGGFETGATVLERRQEIGKLSWQIDEVDDLLGGGMETQSITEVYGEFGAGKSQVTHQMAVNVQLSKENGGLEGGCIFVDSEDTFRPERIDDMVRGLDDEILADEMERREIDGTPSDEEALEDLVDAFLAQIHVAKAFNSNHQILLAEKAKELAGEHEETEWPIRIVCVDSLTAHFRAEYVGRGELAERQQKLNKHLHDLMRLGDLYNTAILVTNQVASNPDSYFGDPTQAIGGNILGHASTFRIYLRKSKGDKRIVRLVDAPNLADGEAVMRVQNEGLKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL7</accession>
    <name>V6DVL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_02176</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="22031" checksum="A6BA0864B27DE08E" modified="2014-02-19" version="1">MFKPALLPDGTANTKPAGPLGRSNRRLLANLHMVTRRQTIIGLASAAVGGGAAASAGTFTSSVSAGADMRVVVVSDLRLEPANDDGPYVTTEDGEVVIAVERLNRHALTEFGDLVRVVNDGNIGYDELRFEFDAGDGDEADEVAAALGITADGDLDEENGTFTLTPDGGLGPGDGVGFGISVDLLPSSESGISDFPESAAELQLFITAAHEGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL8</accession>
    <name>V6DVL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5504" checksum="9A61AAFC7B7A5CA1" modified="2014-02-19" version="1">MGRIRVGFASIRGHESHKIYKPLCSHPSANRRHGVPRGRIQELLLTITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVL9</accession>
    <name>V6DVL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06789</name>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077732.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="131186at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="7448" checksum="7C44319C89932B06" modified="2014-02-19" version="1">MGILDAFGSLASALIAGFVMLAFAILSLFVTVFVVDIAASIGGLSPDDSYVVLGATILAAAAIIAGGAGFALPEGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM0</accession>
    <name>V6DVM0_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
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        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4115" checksum="FFCB3EB26C7EF150" modified="2014-02-19" version="1">MLSVFEGVVEVPVRIAVVRRDPPDQIPPGVLHHAVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM1</accession>
    <name>V6DVM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5428" checksum="471ECAD06CBA24B7" modified="2014-02-19" version="1">MVTLLSFFRLFSTGSTFSTGGIETISTATQAGISTRRAGRRRRTDTGGSVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM2</accession>
    <name>V6DVM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4177" checksum="8C0D13E7D38687D6" modified="2014-02-19" version="1">MLINNKIAPEINTSDLNAKLRSKIDCGIMSFRDDIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM3</accession>
    <name>V6DVM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_06684</name>
        <name evidence="4" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012859">
        <property type="entry name" value="Pilin_N_archaeal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07790">
        <property type="entry name" value="Pilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Pilin_N" evidence="3">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="14125" checksum="8FCC5F34E7A2F238" modified="2014-02-19" version="1">MSPVIGVILMVAITVILAAVIGTFVLGLGDQLGDTAPQASFTVDEVTVNETGTPSDVNVSITKTGGQDLDPNQITVSIDGSRSGTVAEGSDVTDTWQSGTTAVVGPIGEDYESDDTVEVRLIHDPSGNAIFEDTATVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM4</accession>
    <name>V6DVM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_12485</name>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
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            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8255" checksum="E7EEDB8AAFEFE6CF" modified="2014-02-19" version="1">MIAQRLTVPEVRLRLGAISRTGDHSLRIAIDQGGVRGEVETDEPVVKTLLLRLTDERGPPERVIVTIGGERAGVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM5</accession>
    <name>V6DVM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_02146</name>
        <name evidence="1" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077005.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79408at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035185">
        <property type="entry name" value="DUF5305"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17231">
        <property type="entry name" value="DUF5305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="372" mass="41592" checksum="AD46194EF4A50C9C" modified="2014-02-19" version="1">MGEIDRSVRIRALLDRWFLVVAVALLVVAVAGGAWAYQVHATETVETDQVTTERWSETTSYEHSSVIVNESIPFDEGERVTNRPVYYTRLSEEVDVSYRYEYAANDGAVQVNTETRVQYRGIEGETTLWEYSEPLATGTATELDPGTPHTVNATLVITDVYETINTVEQQLGTVGTIEIRIVSTSNIEGTIDGDSVEHTYESEMPITVTPTTFRVLEMETVDETETQTRTVERPVRSGAVESTAPVVLSLLALAGLGGLVHARRTGRVGLSADERELLELHQQEQEFSEWITRGTFPSERDYEQTILVDDLEGLVDVAIDTNKRVIKDEQLGVSTVLDGDYIYVYVRPDSPAEDWLINYADTTMEEFERFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM6</accession>
    <name>V6DVM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.127</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_11135</name>
        <name evidence="1" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.127" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077741.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51529at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047001">
        <property type="term" value="F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="283" mass="30587" checksum="F310E72151335CE5" modified="2014-02-19" version="1">MALAAPDLSGSTAFITGTTRGIGKQIALALADHGCDVVSTGKTTDEDDTELEGSIEQTAREVRERGAEALACELDLRDEDRVEAVVEEAIDHFGEIDIVINNASAIQLANVADLPADRFDLLTDVNVRGSHLVAHAFADHLAERDGAWLLSNSPPVVTDRSPGKAPYAWSKLGMSFITLSLAEELGSDDVGCNTFWPVTTIDTRATRYFGLGTEDDWRTPEIVSDAVLEILARDPAECTGNSFYDEELLREAGVADFAAYNLTDGDPAPMSARMFDTEFEREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM8</accession>
    <name>V6DVM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoadenosine phosphosulfate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_14354</name>
        <name evidence="3" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077008.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="34310at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="2">
        <location>
            <begin position="48"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="323" mass="36949" checksum="C9B7D380E00F9EBE" modified="2014-02-19" version="1">MSEDFPASVDVDYADGEGEDPEDYPSIQHKIEKAVEVTRRGLEQYDNPAVMWTGGKDSTLTLYFINQVAEEYGYEKPTAVFIDHFQHFDSITDFVEHWADEWNIDLVYARNDDVGAYVDEHGLEPGDDIPVSALSEHNQHHIRDILEFEEDTFPFLLDTYVGNHLLKTVALNDALEEYDIDGVISGVRWDEQEARADETFFSPRHDPDLFPPHDRIQPILQFAEADVWDAFWNFVVPDTVEAFPDEGYVPQADDDLPEGVTQEDVPISPKYFAGFRSLGSEVSTDKTTEEPAWLQDLEGTTERAGRAQDKEDLMERLRDLGYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVM9</accession>
    <name>V6DVM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="8817" checksum="3F769F74C7A6B559" modified="2014-02-19" version="1">MSSRVSSATDATSTRPSSARSKAAPATVSGFRPVSSPISATVRSSVALAASRTASCRSVSRIRVVSTRVRLVGNGSGTGPPRRTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW00</accession>
    <name>V6DW00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CheC, inhibitor of MCP methylation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_10753</name>
        <name evidence="4" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007597">
        <property type="entry name" value="CheC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04509">
        <property type="entry name" value="CheC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheC" evidence="3">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="CheC" evidence="3">
        <location>
            <begin position="305"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="447" mass="46579" checksum="A542D0E5AFC4C4CA" modified="2014-02-19" version="1">MRVDVRALGACNRLAEQGAKQAAGALSDLTGTDLAVEVTGASVASGEDLAESFAGRESIGVSVGLRGGLDGEAVLAFDAVNADALLSLLPGGQSMERSAVTEVGNIALGGFLDGWANYLGKAIDMSPPRYFEADGAAVLPDGALAGDGVFLFESRLDATTTDLDFSIYMLPDSGPFRDLIVGKTAPAAGGGNAPAAAANGGTTSTAVPYESLSTFSSLAKEGSANAADNIAMMTGLETSVDVSRLRFVPLADVPAEVGTEPHAGTVFELQGQPSGYLAILFEESSAAAVADAMLPMDPDEPLGDMAENALCELGNVMTSGFIDGWANVLGTTITHSPPEFVHDIGASTISPLVAKLSERQDYGFVIDTAIRTEGIQARCDVYALPDERELARAXXXXXXXDADDSGGERRSAHRGRPPGDRRRPVRPSRDQRRVQPKRVHRCRRGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW01</accession>
    <name>V6DW01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7098" checksum="898B24E36E2C7626" modified="2014-02-19" version="1">MSSMSSVAFFSSASWLAISFSRRREIQKNASSRVSSAISTTTFPSACRPVRPLRWIDRIAVGTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW02</accession>
    <name>V6DW02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="295" mass="32793" checksum="9B513792AAA97654" modified="2014-02-19" version="1">MWLEASGQLPYLSFCSDLPNLQRRGEFYLWFKFKTTRAPFVMSKSRSLSSGQPERAEVDAKVSCPIVCGDYYRATGFFFKTDAGTFLVTARHNVLPTELSQRLPDGQSQTIFTSERTLPEITIYLRNDADWDVFQTDIREAEDVRQTPDIDVIGVLVDFDPTEYGYCVWTEDDIISEPPTEDEIDVVGYDGISFPSPEQEHDVDIYRRQLGLPRKLSLMNPLDSTDPMPTIVLAGVDPGAEGEYTGLSGSPILGESLVGIHAGDSGVGPIDGMKSGDANRVIYSRAEVLLELLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW03</accession>
    <name>V6DW03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_03232</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="1">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="288" mass="32455" checksum="F00256F0AAD16BB8" modified="2014-02-19" version="1">MPLSINQITHWGTLSPQLSAYLWLCLENEQTVFVVGETASGKTTTLNAILSYIPDDSKIYTAEDTAEVIPPHNTWQQLLTREGGDEGSSDVDMFDLVAAALRSRPDYIIVGEVRGAEGRMAFQAAQTGHPVMLTFHASDIVSMIQRFTSEPINVPETFMDNADVALFQNRVKQGDDVLRRVTSVQEIEGYSKEMDGVVTREVFSWDPVEDEIVFQGMNNSYVLEEQIATLLGYADTRDIYDDLEFRAELIERMIQEGIMGYHEVNDAINSFQRDGVEGLPFDMHRNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW04</accession>
    <name>V6DW04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hlac_3501</name>
        <name evidence="3" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077123.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="139702at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="168" mass="19237" checksum="C09095C35CF5468B" modified="2014-02-19" version="1">MKHNGTNLDGDSLRVLDALYRQDDHRLNTSEVRSVTGIESNDRARRRIEKLGAAELADIDKDERASTPIPPKRATLTEEGVEKAEEWDLDPNSTDIRSPEARLQRVERRLNDLEERFDQLESAATRNPDRIPELLETRRLVATLSEYVVTELDADLGVYYPLKDNLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DW09</accession>
    <name>V6DW09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_15035</name>
        <name evidence="1" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4932" checksum="B268B1FE8CD972C0" modified="2014-02-19" version="1">MKDHDVVEPSDHDYGKLYFLTDRFERHTETFEEITSEVDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ0</accession>
    <name>V6DWJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleotidyl transferase</fullName>
            <ecNumber evidence="8">2.7.7.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C471_15382</name>
        <name evidence="8" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023915">
        <property type="entry name" value="Bifunctiontional_GlmU_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03992">
        <property type="entry name" value="Arch_glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="272" mass="28353" checksum="F2D3D614B8D34A4B" modified="2014-02-19" version="1">MLSTAADGSLADIVEKPDDPPTNLANVGCYAFEPEVFEYIDRTPESERGEYEITTTIDLLLDDGRRVDVAPYDGAWLDVGRPWELLEANELALAELDAGDGATGATDAIAGTVEEGVHLHGPVVVEDGARLRSGVYVEGPALIREGADVGPNAYIRGSTVVGPGVHVGHSVEVKNSVLMADASVGHLSYVGDSVVGRGVNFGAGTNVANLRHDDENVRLTVKGERVDTGRRKLGVIAGDGAKTGINTSLNAGVKLGAGETTGPGEVLTRDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ2</accession>
    <name>V6DWJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C441_02802</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078084.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65802at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="296" mass="33134" checksum="07AC453FAD54C9F8" modified="2014-02-19" version="1">MLASVVIPTYNRSDKIGETIASVCDQSVSEYEVLLVDDGSTDPRYGALLNEIDEQYDRVKIIRQENSGPAAARNRGIEEAKSEFVCFTDDDCIVPEDWIERLVESFESGIGAVGGPLQPTEDAEERSPFAQLHRYRNQVVYDQPTEPTVGDTDLPMGGTANICYRLEALEAVDGFDEAFPTAAGEDADLQHRVAQEGWQMKFVPVVVHHNDEYSFTSFKERAIRHGKGTYYFHRKHGIPRSKLRVAISLLGSVVFLPKEVLQTRDLTLASLAVLERALSRYGELKARYNDDVAMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ3</accession>
    <name>V6DWJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein involved in the export of O-antigen and teichoic acid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_14597</name>
        <name evidence="8" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078094.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16767at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="343"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="502" mass="55058" checksum="989AA2F097E0D373" modified="2014-02-19" version="1">MRDRLRAIVEKLVPRGTVVQQAAKGGVWMTMIRFLSQGSYLLMLVVLARLLSPRDFGILGVALLTLSAMKRFSDIGINTALVQQKAADIDEYLNTAWMLAIGRGVLIVVVLFFAAPFIAGFFGEADSELAAIIRVIAFSPLLSGLQNPAVVYFQKDLEFHKEFVYQTTSSFARFVVGIGYALVSPTVWALVAGFVSVSASKVALSYALHDYRPRPSVDRETLWELVHYGKWITGSSITKFVHSEGDDAFVGWFLSATALGFYQYAHRIADMPATQFTAVISSVTFPAYSKLQDDPAALKDALLGTTRLVALVTFPLSAGMALIAPSFVPVALGDEWEPMILPLQLLSVFGLLHGITRHFGGVFNALDRPDYNMKLDTVRIVCLAAVIWPATAQWGVAGTAGAIIGVYLFPMFPLDVYAVSTLTRAHPFEVLYEYVYPAVGSAVMFGVLWYAHGLVDVSPLVELLFTVPIGAVVYTLTVLLLDELFSWGIKRDLRYVVAEVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ4</accession>
    <name>V6DWJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dipeptidyl aminopeptidase/acylaminoacyl peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_07972</name>
        <name evidence="2" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="150" mass="16642" checksum="E59E363A74C14CEE" modified="2014-02-19" version="1">MFGHGFSYGGIAQGFLVTQEPDLFAAAAPEHGIYDLRSAFGTDDTHVWLEAEFGLPWENPEAYDASTAVLDAGNIETPLLVMAGGEDWRCPSSQSEQLYVAARKQGIDAELVVYPDEHHNIGDPDRAIHRLEKILDWYETHDPAVDAEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK9</accession>
    <name>V6DWK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HSB1_32210</name>
        <name evidence="3" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="2">
        <location>
            <begin position="14"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18357" checksum="B1FBC8BFB9B735E1" modified="2014-02-19" version="1">MLGNHIGVADRQVAVLSLAFKPRTGGIRNTRAIPVIEGLLERDANVVAHDPVAVDNMREQFPDIEYADSAADVLRDAHASPVVTDWNQYEVLDESLTRWSTTRHSTRRPAGSQKSTSRRASNSCVSHTAATNNRTENSSAVSYEVKQIDDRCDGKYDISDSIYLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL0</accession>
    <name>V6DWL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PUA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14174</name>
        <name evidence="2" type="ORF">BN903_142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUA" evidence="1">
        <location>
            <begin position="30"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9355" checksum="32EB9B214B916628" modified="2014-02-19" version="1">MPPTTNKTLITSYSIHYTKLYDEIDAFVPHGSVLAPGVVDADDGIRVGDEVVIEGPKAFAVGRAEMSGPEMAGSTRGVAVQVRHVDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL1</accession>
    <name>V6DWL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase D/transphosphatidylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13282</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5557" checksum="ED8CDFF9E76A89AF" modified="2014-02-19" version="1">MVIAVENESVADFYARAYAADWRGGGVHLPIGLLAGFGVALAGAGAVARREIAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL2</accession>
    <name>V6DWL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6936" checksum="40113054292AF9DB" modified="2014-02-19" version="1">MNRRRSKSDAISFVHPSEQGINSPFPGHRGDTFVKRSGGIAPGSRGYPRRSIHEPGFLTVVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL3</accession>
    <name>V6DWL3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cdc6</name>
        <name evidence="6" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="46"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="294"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="58"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="367" mass="41168" checksum="CE6C7C3CF3543499" modified="2014-02-19" version="1">MLSWDESVFRDESVFEIDHVPETFRHRESQLENLKYALRPAVRGSRPLNTMVRGPPGTGKTTAVQKLFGELGARTEVRTVRVNCQVDSTRYAVFSRLFEGIFEYEPPSSGISFKKLFGQITDRLVEEDEVLVVALDDVNYLFYENEASDTLYSLLRAHEAHSGAKIGVIVVSSDLGLDVIDDLDTRVQSVFRPEEVYFPVYDATEIYDILAERAKRGFHEGVIGDAELERVADLTADSGDLRVGIDLLRRAGLNAEMRASKTVSEEDVEEAYDKSKHVHLSRSLRGLSESERDLVRVLAEHDGERAGAVYDAFNDATGLGYTRYSEIINKLDQLGVIDAEYADVDGRGRSRELSLAYDAEAVLDRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL4</accession>
    <name>V6DWL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="2">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_03223</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_IV" evidence="1">
        <location>
            <begin position="27"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11323" checksum="08E824A4A2F1BC67" modified="2014-02-19" version="1">MGAEGSLAAMVDDLPAYPIRRDSVRTEAKRAIVERVGEIAAAEYDDVSTLDGIRVETDAGWFLVRASGTEPLVRITAEARDEADVTGLFETARDLVDRAAADRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL5</accession>
    <name>V6DWL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C438_14436</name>
        <name evidence="2" type="ORF">BN903_147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077297.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84706at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="17692" checksum="8C82C205CF0C0F9F" modified="2014-02-19" version="1">MITIISNILGSPFYLFHALSLILVGYWVYLDATERGSNMNYLWAIGCTLFQPLTVGYLLYRSEIGGRTRTAGTLERIVGTFVVGHLVTIQLWFVLGYMNVVTTITHPPLVELQYYIALFVVGVIPGYWLVWKSGWARTRRKLGWVQEAERTNIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL6</accession>
    <name>V6DWL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome C oxidase subunit II</fullName>
            <ecNumber evidence="4">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C465_07766</name>
        <name evidence="4" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.9.3.1" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078135.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77144at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13913">
        <property type="entry name" value="ba3_CcO_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034214">
        <property type="entry name" value="Ba3_CcO_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COX2_CUA" evidence="3">
        <location>
            <begin position="65"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="171" mass="18385" checksum="CC61AB294A49C06E" modified="2014-02-19" version="1">MHIHAYEKLWLALSIALILALIGTVTYGAVGPGIAMVSDTEPTIDPGALDEDERFSEPRVEQIGENEYAAYVVARQYGFQPDPIVVPENSTVTFYVTSADVTHGFEVAGTNANTMVIPGEVSEITVETDDPAEYGIVCNEYCGAGHHVMEGKVNVVSQAQYEERTSGGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL7</accession>
    <name>V6DWL7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C468_15584</name>
        <name evidence="3" type="ORF">BN903_158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077305.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102727at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="2">
        <location>
            <begin position="3"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="171" mass="18162" checksum="FB308FDD9A8B6063" modified="2014-02-19" version="1">MVGVAFGLAGIGVVTVLLALSAFFSSSETAIFSLPAEWFEKQAAADDPRGHVLKELYDDPHRLLVTLLVGNNVVNIAISSIVTVLVASYLPTGAAVVVTTACTSVLVLVFGEIVPKAFGLGNAETWSLRIASPVRLVERVLSPLITLFDGVTRRMNAYISGDANIEKPYTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL8</accession>
    <name>V6DWL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11295</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077720.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126144at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13543" checksum="AA00A74C57CEAD06" modified="2014-02-19" version="1">MSLLTPAVAFGAALVLFVWAAIGLWVNFDARARRSAHPAFWGVLAPLSGIILFYYLLWWRRGRPREWPPGRVERVTATVVVAGIGGLAVGSLVSPPDPASQLTTWPIAFAGCLPVAYWLVRRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWL9</accession>
    <name>V6DWL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAS/PAC sensor protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C491_21111</name>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334965.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80601at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12643" checksum="9C35B8CB062B18D3" modified="2014-02-19" version="1">MPATAPTRDDVLERVDALGPPGTPVTTPEVAREFDCTKRTIYNRLDALVADGRLRTKKVGANSRVWWRPVDAATHHREAASGRSFDALRGSSRRRTPPSAEYSPGDEDNPSEGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM0</accession>
    <name>V6DWM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6279" checksum="81512496F0F92626" modified="2014-02-19" version="1">MDAPAFHREINVVVRDDPGESLRDTVQVDRRVHSPVTPHRSLKTRGFRADARGTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM1</accession>
    <name>V6DWM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein</fullName>
            <ecNumber evidence="7">1.2.7.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C473_15526</name>
        <name evidence="7" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047553">
        <property type="term" value="F:2-oxoglutarate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="4">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="5">
        <location>
            <begin position="205"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="PFOR_II" evidence="6">
        <location>
            <begin position="478"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="373"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="602" mass="65313" checksum="C589E255360785CF" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM2</accession>
    <name>V6DWM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4771" checksum="B7585895B8784167" modified="2014-02-19" version="1">MSDMSYSRPFDRYENNIVLQTHYSRILYGDIYAPSRSRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM3</accession>
    <name>V6DWM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4901" checksum="8D7C71F75882081B" modified="2014-02-19" version="1">MGTVATDRNRKSPLSPRLGTARSWIGGVTPISRCESVLVILQSCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM4</accession>
    <name>V6DWM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_11003</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="492" mass="51187" checksum="F12FFC35C1902EF4" modified="2014-02-19" version="1">MLNAVDDLGLDPSGEVAAEDDVEDALSNDGTLLAFPKGSYRFGGSVSLDAERVGILGLEAVELSPDFGFDGLLFDGQGAAVDDVLVENVDIDIRAPATTAGIRLNCRHHFHVENVEFVGRGTNPSSGGTTSAFLLAVRSENGRGVLRNVVAKKGSRIDGYEGGNGRIGVWIGWSNKGTVRIEDCDFREFGNNGVYGSRTPGNVEVVGCYFLNNNVCGPRIGGAGSYVENCTVEIDLDRYTGGTVDTSTEFNTRAIVVEQGIQRTDAPALPGGAEIRGCTLHARSSPLSQSVIEQSPVARNLTVRDTEIRCDIDGTPAVRRGPVGALPFRPDRQRPPGPHWTRLQNVTVGGDASGGVAIDLQSAPGSRVTDCEITCRGADRDGVLLDSSPKSAVTGGAIRTDGHPVVVEVDPANSDDDLLCLGVGTVLERFGDDGSGIELTDPSVLRTLARSSGTDDVCLGLGPAASALLAAGSDSLRIGVDALEDGVPSGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM5</accession>
    <name>V6DWM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5895" checksum="757504C0BBBBC1E4" modified="2014-02-19" version="1">MAEHVRIVRRRRIKPLSLRASRAGERRDVRSTRGTTAPRCRLAARRAARSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM6</accession>
    <name>V6DWM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4262" checksum="09E8E587D272EA75" modified="2014-02-19" version="1">MADDRDSMKDVSHTAPNDTSADAVWERGRGPVEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM7</accession>
    <name>V6DWM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KaiA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13387</name>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010624">
        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KaiC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="252" mass="28065" checksum="28F6EF217F5CE06A" modified="2014-02-19" version="1">MRVSSGVPGFDDLVDGGFPEDRLYVVSGPPGSGKTTFCAQFAAQGARNGEDVLYISMHETKSGIREDMSGYDFGFDRALDSDRVTFLDSFSSDGRRFFGLPGDRRDRSGVTNRLTGFINSRDIDRVVFDSTMLLRFLLDDDEDTMIQLLSSLKRTDATTLLISEMTDPSAYSEEHYLAHGVVFMHNYLEDEGMRRGVQVLKMRGTDXXXXXXXMRRGVQVLKMRGTDIDTDIQDVEFTDGGLRIGSAATVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM8</accession>
    <name>V6DWM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4450" checksum="02C892970E2CAC7C" modified="2014-02-19" version="1">MFPYLRLRRDAVNGCHEIESRTDSATSEKPETAVQADRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWM9</accession>
    <name>V6DWM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_10943</name>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8165" checksum="342216C2E59C13D0" modified="2014-02-19" version="1">MPGERVSLDEITGREVDAAVLVTAHDEFRSIDWTAFEREGPDGTRRGIPVVDGRQALDLSGTAYRVYTVGRGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZT3</accession>
    <name>V6DZT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsE</name>
        <name evidence="8" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078223.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60954at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_S5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="49"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="23226" checksum="3321B8AC31401373" modified="2014-02-19" version="1">MSRHNDGWEPRTRLGRKVQDGEVTSMEQALESGLPLKEAEIVDQLLPGLEDEVLDINMVQRMTDSGRRVKFRCVVAVGNRDGYLGYAQARDDQVGGAIQKAIDVAKLNIISVDRGSGSWEDQPGGTNSLTRTAKGKAGSVTVEIKPAPQGLGLAAAETVRNILELAGVEDAWTSSDGNTRTTVNLAKATFNALENAAQSRTPQHAREVHYDEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZT4</accession>
    <name>V6DZT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
            <ecNumber evidence="3">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06000</name>
        <name evidence="3" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.274" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078240.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35652at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="18"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="31072" checksum="AD811B1DEED86E16" modified="2014-02-19" version="1">MTVPTKTLPSGAELPALGLGTYDLDDDETADSVRAALDAGYAHIDTAEGYHNEAVIGDALAEYDRDDVFLTSKVLAKNLNYESVIDSCEASLDRLGTDYLDLYLIHWPNPAISLRETLRAMAELRDRGLVRDVGVSNFSAYQLSCAHHIADVPIAVNQIEFHPWFQRPDLVDYCRETDTAVEAAAPLARTDVFGDEVVAELADEYDKHPAQVVVRWAVDRGVVPLPRSSTPDHVRANADLDWELDEADRRRLDERDRDEPVYDTPARDWTSDVYGIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZT7</accession>
    <name>V6DZT7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rps8</name>
        <name evidence="6" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078228.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91154at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_S8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14199" checksum="9F93BEB30E779368" modified="2014-02-19" version="1">MTGNDPFTNALAGMDNAESVGHLSYTVEPASNTIGSVLEVLYDRGYVDGFEYVDDGKAGKFEVELKGAINECGAVKPRYSAGADEFEKWEKRYLPARDYGTLIVTTSHGVMSHYEAREQGIGGQVIAYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZU0</accession>
    <name>V6DZU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="206" mass="23637" checksum="891747807E564608" modified="2014-02-19" version="1">MTAPAERPASVERKEEAHEEERDQNRVPAVDHVRVPRVQRREQDDGDPRRGPRSIADEQADGGADRDGDQPRLYPCRAGQRVERDGLQERIDLTERRARKDAGVRVERAHPSQPIDQQVGEEDERERDPERAERPRIDPEMGCGALAEGVASRRVSGTYRRERLPWWRHPVIQLIRSDFTTKCFVVAAPDRVRNARPFRSFQAGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZU2</accession>
    <name>V6DZU2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl14p</name>
        <name evidence="3" type="synonym">rpl14</name>
        <name evidence="5" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004597429.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38951338"/>
    <dbReference type="GeneID" id="55595001"/>
    <dbReference type="GeneID" id="65214305"/>
    <dbReference type="OrthoDB" id="91632at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019971">
        <property type="entry name" value="Ribosomal_L14P_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03673">
        <property type="entry name" value="uL14_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14202" checksum="E8E672632E617D32" modified="2014-02-19" version="1">MEALKADVTQGLSKGSLITCADNTGARELKVISVSGYSGTKNRHPKAGIGDKVTVSVTKGTPEMRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIIDDLEEPRGTEIKGPVAREVAERFGSIASTATMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZU5</accession>
    <name>V6DZU5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_01793</name>
        <name evidence="4" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078252.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15879at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="511" mass="58060" checksum="39B98DE0D6D9AE3E" modified="2014-02-19" version="1">MATEATADGTDDASDAPDAYDALLDRVQRWNAVGSASGVLGWDQQVMMPEGGTPARSKQLSALSSVHHDMVTDDETGELLDELDDADLTDEQAAVVREVRREYERADAVPVELVEEISETGSEALQAWEQAKAEDDFDEFAPYLEKHVELKREYAEHIDPDRDPYAVLFEEFEPCLSMERAESILTELREALVPMIDDIRESDRELAVDTFEGTFPEETQEELSREALDLVGYDFDRGRLDVSSHPFTSGNQFDCRVTTRFDETDPLGAVGSTIHEFGHAQYNLGLSQEHFGTPLGESRDLSVHESQSRLWENHVGRSEAFWKEFLPVFQEHFPQTEDATVRDAYEAFNQVYEDNFIRVEADELTYHLHIVIRFEIERDLIRGDLDVEDVPGVWNDKYEEYLGIRPETDSEGCLQDIHWSHGNFGYFPTYSLGSVMAAQLFAAAEAEIDDLDAKIADGDFDDLHDWLGENVHRHGSRYETNELVKRATGEEFTADAFLDYVDEKYGELYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZU7</accession>
    <name>V6DZU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl4lp</name>
        <name evidence="5" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_L4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="PTHR19431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18192" checksum="33634521ABE2CE42" modified="2014-02-19" version="1">MPCRAAPRTRRRPRRTRRETERQGATARHPVGHRGHTDAELVAERGHAFDEDLDLPLVVSDEFEDLEKTQEALSVLEAVGVDADIERSEEGRSVRAGQGKARGRKYRQPKSVLVVTSEEPSRAARNLAGVDIATAGEVNAEDLAPGAHPGRLTLWTESAVSEVADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZW0</accession>
    <name>V6DZW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
            <ecNumber evidence="9">1.3.8.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C467_01908</name>
        <name evidence="9" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078267.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36092at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="230"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="384" mass="42255" checksum="9B63DFA6ED36E10B" modified="2014-02-19" version="1">MEFQLTDEQKQLREEVRKFAEEEIRPVATEYDVEEEYPHEIMDKAADMGLLAPHVPVEYGGIGYSSLENAILTEELFAADPGIGLCISSAGFGAEALMEFGTDGQKERVLPEVTAGDAVMGSAISEPQAGSDVTSVATRAEKDGDEWVINGSKMWITNGTVADYFVVVCETDPEIEDRYSGYSQILVEGDRDGLTTDKITGKLGIRASDTAELRFDDVRVPEENLIGQRGMGFLQLMQFFDETRTAVAAQGVGIARGAAERALEYAEEREQFDRPISDFQAIKHKLAEMHTNTEAARWLTYRSAWAVDNEAGDLTALASMAKEFASRTAVEVADEAVQVHGGAGFVNDHDVERLYRDAKITQIYEGTTEIQKNIVARELLDEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZW3</accession>
    <name>V6DZW3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4212 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C469_02204</name>
        <name evidence="3" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019886">
        <property type="entry name" value="Na_symporter_ssu_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13937">
        <property type="entry name" value="DUF4212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03647">
        <property type="entry name" value="Na_symport_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4212" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11051" checksum="7090BB08C42AD44A" modified="2014-02-19" version="1">MRDHLRIVWTGFAVWVLAVWGPVTLTRLAPGPMTTQMPILGFPLHYFLVAFGAPTSALILAFWYSRKRDALDEKYGIDHATVTKTESRAEAAATDGGSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZW7</accession>
    <name>V6DZW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
            <ecNumber evidence="1">1.1.1.300</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_01873</name>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.300" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:NADP-retinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="316" mass="33683" checksum="59BD8C1FBD0E0B02" modified="2014-02-19" version="1">MTDWTADDMPRLDGKTVVVTGANSGLGFEGTRAFAARGATVVMACRSVERAEDAASEIRADAGGEVDGELDVRECDLASLDSVASFAEGLAADYDAVDVLCNNAGVMAIPRGETDDGFETQFGVNHLGHFALTGRLFPLLDAAEGVGGDARVVTQSSGAHEQGEMDFTDLNWERSYGKWKAYGRSKLSNLLFAYELQRRLDASEDVSGVRSVACHPGYTDTNLQMRTAAESGNPLMKVGMKAANAVLGQEPEIGVEPMLYAATADVDGGAYVEPGGLMNMRGHPTVGRSNDASYDREDARKLWEYSTEATGVEFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNT2</accession>
    <name>V6DNT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome d ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C465_01734</name>
        <name evidence="12" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075835.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20297at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK37909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="482" mass="53131" checksum="789BE1B99ABF0DF3" modified="2014-02-19" version="1">MFSTVLSDALIQGWVLQLSPELASRAQFGWTISVHIIFAALSVGLAPFIIYFTWKDVRSDAERFTRLRSFWVKVFAAGFVMGTVTGIPMSFQFGTNFPQFAEVAGEMIGGPLAFEAKMAFFLEAVFLGVLLFGRERVSNRTYILSSVLVGVGAWLSAFWILIVNAWMQTPQGFEMVMRNGMEVAKLTDPIAAFFTPRMPWMYVHMVNASVISVALLVAGVSAYIVWKKRDAAAWNTALKIAVIILLVTAPLQALHGDAYGRHVADTQPQKFAAMEAHYETGTADLHLLAFPKSIDAITDPKAENLFTVSLPGVGSFLASGGDFDAEVLGLNEYEENPPVAMVFWSFRFMVGLGFLFIGLALWGGYLIYDGRLSESDRFLKAIIAASPLGYAALLTGWYVTEIGRQPWVIQGELRTSEAVSSTLTGTEATLTLVGFVVIYIGLISVALYVLRWLVRDELRELGVKLSDDDRWYGPVPKVTSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNT3</accession>
    <name>V6DNT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_01749</name>
        <name evidence="2" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="13956" checksum="B1A7B9020D2CB81E" modified="2014-02-19" version="1">MSQSPNETWSVTIVIPEESSLDGAGETHTIDVDEDETILAAARSAGIWLQADCQQGWCTTCAARLIDGEVTHPNARRYYDEDREAGYVLSCTAKPRADSTLVVDQYDDFLEFRAANDKPPGNSKLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNT7</accession>
    <name>V6DNT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5918" checksum="1DB3D28498EF53AE" modified="2014-02-19" version="1">MFGSLSRPFLAAADKTIRIPLTDQWGAVVSVGYRAGIYICRDGIVSSEKYQLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNT9</accession>
    <name>V6DNT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfurtransferase</fullName>
            <ecNumber evidence="2">2.8.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_15921</name>
        <name evidence="2" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9894" checksum="280BBE06BDF89CB0" modified="2014-02-19" version="1">MKLPGSDEGAMRGGHVPGATNMFWAENVRSNGLFKSREELVDVYGSRGIAPDDDVIVYCRIGERSSITWFVLEELLGYEYMWHYDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNV0</accession>
    <name>V6DNV0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HAH_5058</name>
        <name evidence="2" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075837.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96961at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="15593" checksum="24D87F845C756982" modified="2014-02-19" version="1">MPDSVSKQLRSDMECEGLLECFHGHKPLDRICFEVLVESEEPLTVDEIGEATDRERSTAYRAVQRLLQSGLISKEQVNYDQGGYYHVYQPTDPEQVADEMQRMLNDWYAKMGQLIQEFENKYNDTDPSEPNTAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNV1</accession>
    <name>V6DNV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_00322</name>
        <name evidence="2" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="6954" checksum="C5551785AF5E412F" modified="2014-02-19" version="1">MTDSIDPAIPLDTNEFVEWADRPRITTILPAVVIGVLLLVSGNVVSITQATPLFLAVVSLGVAIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNV2</accession>
    <name>V6DNV2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0033 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14544</name>
        <name evidence="3" type="ORF">BN903_122</name>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075795.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124510at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="1">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8550" checksum="0F72C3DB9DE8AB50" modified="2014-02-19" version="1">MSSQYDIAETLDVKGASCPMPVVKTKGAIDDLAVGDVLEVVATDSGSMSDLDGWAAGTTGVELVNQEAGDDVYRHYVRKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNV6</accession>
    <name>V6DNV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_00317</name>
        <name evidence="2" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7704" checksum="CB91A79C701486B1" modified="2014-02-19" version="1">MPTGKPLDEDEEIVWSEKLHESSLIPALVIGLPLSLVLIGLFIIAGAYLQRKNTKYVVTALLKSLESDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNV8</accession>
    <name>V6DNV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_15430</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075798.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90849at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="15868" checksum="6846EBCD62E9BE54" modified="2014-02-19" version="1">MEKDLFERILVPIADPEDAEATARALRPHLDPDTTLIVTHVVQGETDETSVKRGRDQFAGATYETFSDILYRRDLQFEWATLEAREVAEAIIDGVEMTEATLVAFTPRDIDTWSRTISGDPGGQLIRESDVPVMVFPNQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNW0</accession>
    <name>V6DNW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Archaeal flagellin N-terminal-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012859">
        <property type="entry name" value="Pilin_N_archaeal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07790">
        <property type="entry name" value="Pilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Pilin_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="12672" checksum="C57E17C40F7D91F6" modified="2014-02-19" version="1">MDDTRAVSPVIATILVVAITVILAAVIGSSLLGLTSTLKEPAPVVSLSVADAPENAPPPRRSTNGEITNWAEISHNNGDIIHASDLKILIKNSSGTTVATLQQSNSYSALLKSLESYMFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNW4</accession>
    <name>V6DNW4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C461_13681</name>
        <name evidence="2" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4794" checksum="84D85EC6BE9B2350" modified="2014-02-19" version="1">MPGVSAVDPILWTSLFLASFAVAGAYQLWLNRFSVARQLRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNW5</accession>
    <name>V6DNW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6376" checksum="70FDCAAB55AC7134" modified="2014-02-19" version="1">MLKSYSSDSFTRLRTDSHSAATSRRSRSTRIAVKGCVAPSRPAIESLSIGSTFTAPVAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNW6</accession>
    <name>V6DNW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CopG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_3094</name>
        <name evidence="2" type="ORF">BN903_139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075847.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106015at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10432" checksum="6451DDE1481346B9" modified="2014-02-19" version="1">MSEASSPPEKTTVNIRITETFLSDVDATWEDLGYNSRSEFVRDVLRDAVKHPEFNRADLKAIAASEVDIQEGRTHSSEEIKAEYGREDTSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNW9</accession>
    <name>V6DNW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C453_00740</name>
        <name evidence="1" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="295" mass="31848" checksum="B5ACE1D7419E8DD6" modified="2014-02-19" version="1">MQHYVMEREGYYEDIPAEVAIERFNSGPSVVKAFASGEVDVALFGITPAMVLADKGTDAGILAANSRNGFKIMGTTELVDLYEEEGEAAFERFEQEHGRKARFGAPPDGSVPDIVLRYWIQEDLDLGEMESVIAKSKVPPAKAVQTIQSGDIDATIIQEPFATIISQNDNFGELAWSGNILENHPVTVLFANRKILDDTEVSQSLAEQHTAATEFTTGSPDRAAAHAASVIGSGVSKDLAKAAMESKASDFLSDPHAITDQATTMGEFVANVGNIEEPVATENLFAFDPYDTIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNX0</accession>
    <name>V6DNX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase, IS605 OrfB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C454_12073</name>
        <name evidence="6" type="ORF">BN903_132</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="5">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK37932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="15214" checksum="AE94E603194B9923" modified="2014-02-19" version="1">MAVEDLDAKGLVELPGNSRNRAGAAWGTFLRMLEYKCEREGTHFVSVNPRGTTKECASCGVSTEKPLWVREHSCPACGFEADRDANAAWNILSRGITKQLGAGRSESTPVESALPVDTPVSAKRVVETGSPTLKREPVGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNX1</accession>
    <name>V6DNX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C492_07050</name>
        <name evidence="1" type="ORF">BN903_144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075852.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104339at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="171" mass="19714" checksum="8C477F735AAFB294" modified="2014-02-19" version="1">MADLITEYADYDSFAREWHSDTLADYDVSLDEARERGLLNEQQTRKLWQLLGLLDPEECLLQLPKWLAEKKIKSTNRTTPTIFVGSISRETEDAILFKSSTAAQPLMGLAHQMHSLAEGIERTEGDTDRHKRLTEQFREHERKFADRDGLPSLSDEWLPKSQLGTIVRRCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNX4</accession>
    <name>V6DNX4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4121" checksum="66E5A70D345965BD" modified="2014-02-19" version="1">MMLEFAGLFLLLLFLGIGMYVYVDRYGGFGGGERASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNX5</accession>
    <name>V6DNX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4799" checksum="FBECFE776D207E46" modified="2014-02-19" version="1">MRITDSQTYGATVEFRILGSVEILFFRQIFTRNTRSMRAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNX8</accession>
    <name>V6DNX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">L593_14465</name>
        <name evidence="8" type="ORF">BN903_149</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.25" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075856.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71942at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="303" mass="32963" checksum="FD3C43F023B91865" modified="2014-02-19" version="1">MPAIQTHSVSKRYGDVTAVDRVNLTIEEGEIFGFLGHNGAGKSTLINMLLDFARPTEGQVEVFGMDAREQSVAVREHMGVLPEGYDVYDRLTGRQHLQFAAESKDVDIEPMAIAERVGIRDDADRPAGGYSKGMAQRLVLGMALIGDPDLLILDEPTSGLDPGGARRMREIINEENERGTTVFFSSHILEQIEAVCDRVGIMHEGRLQAVDTIDALRESAAGGTKLHVTVDDLNEAHLDAIEAVDGVDSAWIADGAFVVTCPNDTKMDVLVALNHAGVDVLDFTTEEPSLEDLFVEYTAEGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNY2</accession>
    <name>V6DNY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9356" checksum="771803C3F6FF1CFB" modified="2014-02-19" version="1">MFEDRAGLIVERAVAILTEIPLKHPIAAVPNHRFATAAWAIDAVAPANLFEQVRGATFRDERLDREHRSSGDAVASPLPAVTSSYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNY3</accession>
    <name>V6DNY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C468_06862</name>
        <name evidence="3" type="ORF">BN903_154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031604">
        <property type="entry name" value="Ferredoxin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16947">
        <property type="entry name" value="Ferredoxin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="215"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="344" mass="37426" checksum="E06E2BFD39EE33CB" modified="2014-02-19" version="1">MSTADDGDTLPGIPNVGKADLDAMVENERPDPREELADVEADTDLGVAMAEDAKRVARGELSGDEYWEKYDEAAADEFGEAYRETPNPAVDAGDQTVTTETAESLSCAVGSMDTVSTETAQVEGEETEGGIGTGDEKWGMVIDLQKCVGCDSCTVACKSENRTPPGVSYNVVMEEEHGEFPNVTRTNVPRPCMQCDNPPCVQVCPVSATYKMDDGVVNIDYDRCIGCRYCNIACPYGARYFDFGENYDDEVDEAGELTSPEYGVDRGPREEGKSPIGNIRKCSFCTHRLERGEEPACVETCVGDARNMGDLENPDSDVAKMADSSRAFQLKEDEGTDPNVYYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNY7</accession>
    <name>V6DNY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">L593_14475</name>
        <name evidence="7" type="ORF">BN903_147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075854.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK37947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="273" mass="28383" checksum="E4C64CA5D4041752" modified="2014-02-19" version="1">MSWRAVSKNDLRVALATRGVWTLTAGLLVLLTGLGYVVPRLAGSSEVPFSAYLDILVAIVVPLFPLIGLVLGYRSIAAGRASGTATLALSLPNSRRDLVAGKFVGRATALAASLAIAGVVAGGYLLASYSDFAAGDYLLVLVLTFGYTLAFLGIAVGLSTGIASSRRVIGAAFGAYALLALLWGTLVDAVLNVLFRFEPPMETPAWVEFAKFIEPGTSASYLFATGLGVGTAPPEAVIGTEQFVSTVGALVVLIAWIIVPVVLGYARFQRGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNY9</accession>
    <name>V6DNY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4993" checksum="E80212F15142D5BE" modified="2014-02-19" version="1">MNGGIAVRDIYLAVDERGRLDKWGWRAADYLGDGNDEFERCDAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA0</accession>
    <name>V6DSA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_01884</name>
        <name evidence="2" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18886" checksum="3C3C8FA047CA4761" modified="2014-02-19" version="1">MPEVCDRLGISSDAPPDPTTFYHSFDRYEMYIWRALLRVSAQQNPQSGHVSLDSTFFERFHASQYYYQRRGQTVKTVKATTLTDTESLAVLDVHCCIGREHDTKAGPRVVRRNADDLRAVAADNGFQDWYSEYEIAALDVEYLVYYRGSTPKAVANNALIQAKGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA1</accession>
    <name>V6DSA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4274" checksum="82CE2CB792BCB2E7" modified="2014-02-19" version="1">MSHDTPIVVKPIVGGSQLPNRFAGESRADDTVSSSGTPSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA2</accession>
    <name>V6DSA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HAH_4279</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076818.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116794at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="133" mass="14131" checksum="3C0F399768465DEB" modified="2014-02-19" version="1">MTAQTSDGSFITLPSHPLGYVAILAAIVTGGIHLVLGRGVLGFNQLLGALFILNGLGFLGGIGLYLSRYWQRELYLVATGYAVVTILALFVFQGASLDAFYMQGELNPMAVVAKVAELVVAVVTLYLYTELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA3</accession>
    <name>V6DSA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7830" checksum="C6D13761F606666D" modified="2014-02-19" version="1">MDPYGVSGLADQSDVRKDRFKILDNASDDAPTGEFAEMRWLDGTMVSRPSPFRSPTGPPTGYISNSIAGQPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA4</accession>
    <name>V6DSA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine/putrescine ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C464_00234</name>
        <name evidence="6" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076256.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65226at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="84"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="301" mass="33001" checksum="9A7DD34AE175E2FB" modified="2014-02-19" version="1">MGTIQKLGDAFERRGERAKLALMVGPGVGWLLTLILIPTAFLVMVSFAEVNQSYDVVWSFSVSNYRELFVGESGWFTTPFVDSFFLSLRIAGATTFLTVVLAYPVAYLLTRLSGRRFKIVLFAVLVPFFTIFIVRIYSWLSLFGSQGLINSALLATPLVSEPLGVFEYGVVAVIISLTHAFFPYMLLTLYSSLEGIDYGVIEASRDLGATRLEIAKDIVIPLSAQGLITGCVFVFVPALGTFITPQFLARGKFTMIAEVLTSRINELYAINYGAAGSLFLIIPTIIAFAIVMRTTSLEAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA5</accession>
    <name>V6DSA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_14555</name>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9946" checksum="F6466EE39852E2B4" modified="2014-02-19" version="1">MGDSDSPTVSVSLSGPTDISAVLNRAGIDHVSVHDHRVLAIYQTAIFNVTTDPHPLSTAQSLEIECWEGPIPSRADGRSLEDILQDFVNVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA6</accession>
    <name>V6DSA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron/cobalamin ABC-type transporter ATP-binding protein</fullName>
            <ecNumber evidence="2">3.6.3.34</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C443_00442</name>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.34" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="119" mass="13082" checksum="EB0435B7DAFC8D18" modified="2014-02-19" version="1">MDEPTTFLDPRHQLEVMRVVEALRDGSDTTVVLVLHDISQAARYADNIVALKEGSIHASGPPEAVVTDNLLTEVFDINSEVIETEHGPVVVPLNPIEENHPGQMGESEEGRRSESSRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA7</accession>
    <name>V6DSA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5555" checksum="3E502BA073715B1D" modified="2014-02-19" version="1">MVIPLTGIGFATQIGEHSLQYVVSVYLILVGMFVLTAGIAYTDHSVNEWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA8</accession>
    <name>V6DSA8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C464_17237</name>
        <name evidence="10" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076809.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40988at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="197"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK39051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="430" mass="46898" checksum="D86ADB152B51F2D5" modified="2014-02-19" version="1">MASASTATDETSEEPTEEESALETARRQLQHAADHLDIDQNIVERLKHPKKVHEVTVPIERENGDVEVYTGYRAQHDSVRGPYKGGLRYHPEVTREECVGLGMWMTWKCAVMDIPFGGAKGGIAVNPKDLTDDEKEQLTRRFTDEIRAVIGPTKDIPAPDMGTDPQTMAWLMDAYSMQEGETIPGVVTGKPPIVGGSKGRDGAPGRSVAIIAREAIDYYGKDIKEADVAIQGYGSVGSNAARLLDDWGANVVAVSDVNGGVYDANGLDTHSIPSHHEEPEAVMDHGAPETVSNEELLELDVDLMIPAAIGNVLTADNADDIAADIIIEGANGPTTTTASAIFAEREIPVVPDILANAGGVTVSYFEWLQDINRRSWSLERVNDELETEMLTAWQDVREEFEARDVTWRDAAYIVALSRISDAHEARGLWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSA9</accession>
    <name>V6DSA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C463_12692</name>
        <name evidence="5" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.26" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334906.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36410at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047964">
        <property type="term" value="F:glyoxylate reductase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="84"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="125"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="333" mass="36011" checksum="9675DA60EE842245" modified="2014-02-19" version="1">MNERTDAATDTEATTVLLHHSISAVFGGDFVDGMRSQLDAVLPSTGRIETATTAEESGTVISDADVILTIRPVNDELPTGTAPDWIQTLNSGVDSYDLESLGERGIAVTNAAGVAANPIAEQVLGYLLVFERRIHKGIRQQERDGIWQRYSAGELRGKTLGIVGVGAIGTRVAELASGFDMKVIGTKRTPETAPDVVDEAYPPDGLPKLLARSDYLVLACPLVESTRELIGTDELMSMRSDAVLVNIARGEVVDQAALATALQQNRIRGAALDVFDEEPLPPASPLWDLPNAVVTPHMAGSTPKYADRIGTLFEENYRRYDDDELEELRNRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB1</accession>
    <name>V6DSB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C444_18072</name>
        <name evidence="1" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076822.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65151at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="288" mass="32223" checksum="0600F1D72C9CEC4E" modified="2014-02-19" version="1">MVAKYSEKKTADGKTDRLATSAVESVAFLARSEHRLHILDLLADDSYSRGELRDRTDATRVTLSRILSDLEDRGFIQQRNADSEYELSTFGELVHRDLSCLLDTISIGQTYPKLISRLPTDWFDFDPQCLVDGEHVHGNSADPLAAARVIANAVRDGSSCESLVGTFTSLPMHAYKEDVRAGGDTDVRVVFDSGVTETMLEDQSLRAEWQEIESATDSTVYYSLDERVPCTVDLIDDETVFLTIDREQETGFDIISCSHPDVVAWADRVISEHRNRAVPLSRRMLNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB2</accession>
    <name>V6DSB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_03718</name>
        <name evidence="8" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="27815" checksum="CEABAD1D5A524460" modified="2014-02-19" version="1">MLVGANLAVSGAIFQIITRNELASPYILGVSDGAGLVVLVVLTAFSELLPFVPVLAALGGGAAFLLVYVIAWKNGTSPVRLVLAGVIVGTVFGSVQRALFFFIDDLSTVMSAQAWLSGSLLNTDWGEVRIALPFTVLALALAFVVTKELDVLALGEETADSLGMPVEKMRFAVAGIAVLSTAAAISVAGLIGFVGLIVPHMVRNVVGGDSRRLLLGCLFLGPALLVGADVGARLVLNPIQLPVGIITGLVGGPYFLYLMRKTENLGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB3</accession>
    <name>V6DSB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4348" checksum="C01CF372927228DD" modified="2014-02-19" version="1">MIIAHRSSGGRSSRSSANPSRGVCIWSVTGQWTFRQVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB4</accession>
    <name>V6DSB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_2235</name>
        <name evidence="1" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076813.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69155at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="22597" checksum="72604B8832BB9BF5" modified="2014-02-19" version="1">MTAKTSDTNTKVARVIRKYDLDGMGANLETAWTGKSGERTSLRNLADEFNEAVLEAALREANVSSVSVNVSSTYDALQSESRSSKMRVRRHLEREEIDVDELTGDFVTHQAIHTYLTEEREANFPGPSDDMAERKIETIEKLEGRVSAVAETAISSLANADELDDDGYDVLVDVRAVCPYCGADLPVGELIRQGGCGCGDKSEATDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB5</accession>
    <name>V6DSB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MATE family drug/sodium antiporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C485_00690</name>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076824.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="52466at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="493" mass="52605" checksum="7361A6D4EEF754D7" modified="2014-02-19" version="1">MERFSRIRSLFKGPEEFDLTSGGIGKPLFFLAMPIVVTNLFQTAYNLADTFWLGQYSTDALAAISFAFPMVFLLISLGMGISVAGSVLVAQYTGADEEREAEYAASQTVTFAAIASLVLGVVGYFGVDTFLSLMGASQDVLPLATSYMEVISLGLLFMFGFAVFIALMRGYGDTITPMLVMFGSVVLNIIIDPFLIFGWTVVENAPLVGTVAFPELGIQGAAIATVFSRALALVVGLAIMFRGNRGVQIHLRDMVPDLSYLRRLFRIGLPASIEGTGRALSMNLLLVIVAMFPDTVVAAYGIGTRVFSVVFLPAIAVARGVETMTGQNMGADKPDRAEQAAGLAAKFLFGVLSVAGVVVFLFPEPIVSVFVGADQADAAQVVEIGGQFLRYVALTFGFIGIMRAYTGSFRGAGKTLTAAAISVLTLGIIRFPIAWISAGPLGEVGIWLSFAISNVAGAIIAYAWYRRGTWRESDLTESRVDLDETSVETAGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB6</accession>
    <name>V6DSB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C435_16755</name>
        <name evidence="4" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076826.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71656at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="205" mass="23377" checksum="28CDA3C00CC830D3" modified="2014-02-19" version="1">MAEPPKGSSSDPDEEIMRATYRALQKHGYADLTIKRIAEEYGKSTAAVHYHFDTKDDLLAAFLDYLLDQFVDTIHNIETTDPEQRLELLLDKLLVDPQDHHDMLIAMLEMRSQAPYKEAFADRFQQNDEYIRYMLQTLVDHGISEGVFTDVDSKHVARALMTIVDGSRARAVVLDEPDSLETARRAADEYVNAVLRANTDEETDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB7</accession>
    <name>V6DSB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">OE_5143F</name>
        <name evidence="8" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="463" mass="48408" checksum="F456C5CDA99B0EF1" modified="2014-02-19" version="1">MDRDSWVSNVGFVLAAIGSAAGLGNIWRFPWLTADNGGSAFLVMYLLLVVGIGVPGLLAELVLGRRGRQTPVGALRSLIGSRWGTPLGAFNVVTTVVMLSFYSVVGGWVLRYTLLSPSGAYFAQPQQYFRHASHGLPAVGFHLLFLAIIGIIVYFGVSRGIERVSKIMLPAVVVLLGGLAVWTATQPNTAAGYAFYLDFDGDYLAAHFFDILGPAAGQALFTLSLGAGAMLTYASYLDDDVSLPRDTLAIAISNTMIGVLAGLVVLPLLISQGIGPGRGGPGALFVALAAAFSSLPGGTLVATVFFLTVLLAAITSGINLLETPVATLVDNYGMSRRLSTLLVTLLIAVTGSGLALAGPAFRFVSGPVVDVMLTVGLFAFLAIVGWVLRDDAVTEFRTGAGRLRGLATPWVLAVGWVLPVVVMFSLTTTLTSIASLSVPTSTRVIIAMVTTLACRAAVTRTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB8</accession>
    <name>V6DSB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_01427</name>
        <name evidence="3" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5412" checksum="191481BD51B9BE41" modified="2014-02-19" version="1">MSFIEYVIPVFAAIAGWLVLGQNVTPATVAGFAFILAGFVAAKWRALRGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSB9</accession>
    <name>V6DSB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase and inactivated derivatives-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nmag_2595</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="13389" checksum="1E1AB396D5CF5977" modified="2014-02-19" version="1">MDYLNEIAVEELQEALNNVDENKPTQRLLAAIAYKNDVAQTELAEWYDTERKTIYNWLKRLDTDDPLEQAVTDAHRSGRKRKLSETQQRECEQTVHESPQESRRMLERSPSSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC0</accession>
    <name>V6DSC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hmuk_0940</name>
        <name evidence="2" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076828.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62124at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="29971" checksum="BA1FFE1E354D1930" modified="2014-02-19" version="1">MVELSLTDCPAIVTGASRGIGKEIATTFAEAGGDVAICSRTYEDVAAVANQLDAAHDGQVIPVECDVTDSEAVRNLVDTTIEEFGDIRVLVNNAGGSVESADLLHRCSEEEFEWMLELNLKAPYLLAREVLPAMIAGDGGSMVHVGSVNGLFGIGLTGYSEAKSGLLALSRNIATHYGQYGIRSNVLSAGTIETQNRRDEMESTEERSGETSVRDRWLDQYPLGRFGRPREVADTALFLASEHSGFITGENLVVDGGLTAGLPQSFENEIYQADEPPAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC1</accession>
    <name>V6DSC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4657" checksum="5E19306A643C729A" modified="2014-02-19" version="1">MYTVSNYEHLGQIDLTQQIHQLNQLMNGVIEQFTHQRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC2</accession>
    <name>V6DSC2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="1">1.8.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_04138</name>
        <name evidence="4" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076268.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66699at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="3">
        <location>
            <begin position="23"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="22950" checksum="48E3817FC53D2080" modified="2014-02-19" version="1">MTITETQIREYDSRAMKSAETATATFGTGCFWGPDARFGAMDGVVRTRVGYAGGTKVDPTYHSLGDHTEVFQVEFDSDTIPYRDLLSQVFHSHDPQHQTRKTQYQNIVFAATEDQRAVLDEFLTTRGLTAEGIGTRVEQLSRFYPAEDYHQKYKLRSVSSFMDAFEAAGYGDKELRESPIAAKLNGYAAGHDVAVAEGLSTPDRGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DSC3</accession>
    <name>V6DSC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HFX_6187</name>
        <name evidence="1" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076830.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16705at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="379" mass="42744" checksum="54A6E54031D031E1" modified="2014-02-19" version="1">MEFATWAYPWDVRDEGIDTVSSRLREIGIGEMNLATNYHSVQAFSPHNPVRKTHFAHASSYFYPDGEYGELRPQPYEGMDEDWVDSIATATDDLKLTSWTIGCHNSRLGMAHPDLTLTSPYDDDLVFGLCPSHPDTQQYLRSLVTDLASRETFDRIELETFDYFYGTGFGWHHQKIHAELGTLGEFLFGLCFCDHCRNIATNRGVDVDRVRRASVKALDDIIAGRLPSDIVPEQWLRQSPEVADYVDVRQRTLTDLYADLASAGGETELGYYVGMPEAGREWMAGADLTQLSDHVDYFCLPAYESSCEDVLRSYRLVDSLDIDVPIHVGLLPGHPAIDDPNTLSRIVDGLREEGVPRVSFYNYGLLPDRSLDWIASAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE3</accession>
    <name>V6DWE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6200" checksum="5D572A6E821D642F" modified="2014-02-19" version="1">MRSLINQPAAGAPPSGRPRRPQGVREGVGGPEQRGGPPTGRERSSRLQPARSAGDEVGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF0</accession>
    <name>V6DWF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1243</name>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078062.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="14706" checksum="B8112C975B917CAA" modified="2014-02-19" version="1">MTSRVLVPMDDSEMAERALRYALKVHSDAEITVLHVVGGPSSMMGRATGIALADDPQAAAQEQASDLLDRAHEIAAESDSEIETIVRVGHPARAVINLSEEFDAVVIGSHGGSLADRLLVGNVAEKIVRRSAAPVTVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF1</accession>
    <name>V6DWF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5448" checksum="B22B80232B8690B7" modified="2014-02-19" version="1">MKPRAYECYPHGDTSVSTPGNVRLYRYATTPKTVATANETDRVLGSGEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF2</accession>
    <name>V6DWF2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase</fullName>
            <ecNumber evidence="2">2.7.7.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14424</name>
        <name evidence="2" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077258.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36958at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="324" mass="35565" checksum="20F57ECB1CF4F9AA" modified="2014-02-19" version="1">MKAVVLAGGYATRLWPITEHRPKMFLPVGENTVIDEIFEDLEADDRIDEVFVSTNERFADTFAEYLDDSPFEKPTLSVEETVEEDEKFGVVGALEQLVERENVEDDLIVVAGDNMISFDLGDFADFFEDKGTPTLAAYDVGDRERAKSYGLVQLEGDEVIDFQEKPDDPQSTLVSIACYAFPAETLPKLTTYLEDDNNPDEPGWFLQWLQQRGAVHAYTFDGAWFDIGTAESYLDAVEYALDGGTLVADDATVEGSDLGDVVHVMSGATVTDSTLDRTVVFEDATITDSEIRNSVIDTGATLEGVDLSGALIGSYTSITESDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG4</accession>
    <name>V6DWG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halxa_0032</name>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078058.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="133867at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="194" mass="21639" checksum="2FA3C082527CF3E6" modified="2014-02-19" version="1">MAVDEDQTATEAGDSDGYGGNYNETCPIPPATVPDERLDDDFKGAVHALRRERDSTHGQPTVVDTDGNQALIWLGEYDLHTYCERWDDSSAELYILVDQSFDGSDPHWVIMAPAVTVDGQDVGDIQCRSTFADPNGSHYDKVEKVLEVADEDSGIAFSWRWAKMNRQPTRMRDLADAHTLVQFLLRLDETEGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG5</accession>
    <name>V6DWG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="9132" checksum="19B6DCF516F8EE3C" modified="2014-02-19" version="1">MFVFVGLYVPRGVSKSNPLRGYCALLREGKILPQFSGHERMGNEGEWKLLRDGENTSKEFRRIERETETPRTQRFEPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG6</accession>
    <name>V6DWG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="18990" checksum="915A56AAE02A2C11" modified="2014-02-19" version="1">MNHYIPPDTNDGMVRFINCKASNNGGSGFDIRGGNHQFINTVAENNEKSNLSISNSTASIVDSRFSGGEKTDIGVDVGRDAVLNMSGTELKDHFDWDLRVAPDSMVDIHQVSANEMLDDLRGDRYHPDGIINHELIDTTERAQQWEKRGKQAQLAGMPVIGALAENMLFNMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG7</accession>
    <name>V6DWG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4851" checksum="77CA595DA24E7A75" modified="2014-02-19" version="1">MTRSLTPREAGRRGTAGPMSSRRGRATRTRESSATATRPSGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG8</accession>
    <name>V6DWG8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C444_12157</name>
        <name evidence="1" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334961.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87145at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="314" mass="35737" checksum="C3F0D5B2099434E9" modified="2014-02-19" version="1">MTLVDWLRQIHQNKQDYSTAFAFKQAFHELYLGLLRRGQSVLNRGEPHWSGDWDVLLVLDTCRPDVLREVATTGQFDWLPEPREHSTWMSAGTTSDEWLAVMFDPEFDSELASSTYITGNGFSQGYDTDRLALYDFVTARPLGDGLTAVPPDILTDKAIDAWRKRGEIGADQLIVHYMQPHTPFRSKPEWFSKGHSDKATWGEGFTELRDGNLDSKEFYDAYKDNLVWVLESIERLVNNCDADIVITADHGNGFGEGFVYGHPEGLPCKTVREVPWVELSGVDEGSYQPVHTVLDSKEISEEELEEHLRSLGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG9</accession>
    <name>V6DWG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="7382" checksum="E75E54BFF7D57E8A" modified="2014-02-19" version="1">MTGDRNGGDNTRSHGYRFRGRVRSAIARVRLYNRRPQELCRSTVETRAWTDNSSSRCSSRFSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH0</accession>
    <name>V6DWH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arsenite transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C484_07736</name>
        <name evidence="8" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="62"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="377" mass="40920" checksum="2394527169C1AC5F" modified="2014-02-19" version="1">MRPRRDADILQLIRDGERFTEPLARKQIHANDTLLIRAGRDTLEQLANADDLAIEGSVETDEELEPEQTNDQSIVEVVIPSRSFLVGETLTSSTFRERYDGNVLALRSRGELIRDRMENIKIRAGDTLLIQADTDSIDRLAQNRDFILAHEADDPDYRTDKIPHAIAIMFGVVGFVAMPWEFLGNGLASLTGVEQFTMLAAAQQDILVTALAGVVAMVVTGVLKPNELYDSVDWDVIFLLAGVIPLGIALEQTGAARLLGNLVSASAEFLPVILVLWLFYIATGLITSVISNNASVVLMIPVAAASAAQIGTNPFAFVLAVTFAASTAFLTPIGYQTNLFVYGPGGYTFADFFKVGAPLQLLLSVVTTLGIAFFWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH1</accession>
    <name>V6DWH1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">aroC</name>
        <name evidence="11" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077268.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50229at2157"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="257"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="259"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="313"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK39708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="395" mass="42710" checksum="93E88B92E41FD355" modified="2014-02-19" version="1">MNGNRFGRLFQLTTYGESHGDAMGVTVSGVPAGVELDEEAIQAQLARRKPGQSMITTSRGEPDEVVVNSGVQDGYTTGTPIGMVIQNKDARSGKYEPYVTAPRPSHGDYTYSAKFGTRNWGGGGRSSARETVNWVAAGAVAEQVLDASDHDVEIKAHVNRIGDVEADAVSFEQLLERSEENDVRCADPEAAAEMQELIEEYQERGDSIGGSVYFECRGVPRGLGSPRFDSFPARLGQALFAIPATTGVEYGLGRDATDVTGSERNEDWTFDDGESFDHVESDEGDPVPVGNDHGGLQGGITTGEPIYGEATWHAPTSIPKQQRSADWETGEEKEIQVVGRHDPVLPPRAVPVVEAMLYCTVLDFMLLAGRINPDRVDGNPGQYDTDYHPSSPDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH2</accession>
    <name>V6DWH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formyl transferase family protein</fullName>
            <ecNumber evidence="2">2.1.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">wekD</name>
        <name evidence="2" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="1">
        <location>
            <begin position="66"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="239" mass="26990" checksum="0D04B4B86A1CDD8A" modified="2014-02-19" version="1">MVSVAFFGSHPLGIECLDRLHAHPDVDVELVVTYPPDETHWWDGSVRDRAAALGYRTLPLADERDVLNVPVDYLLSVYYPNILDAELLDHPREAALNLHQAELPRYRGSNVFTHSILNARRDDHWRHGTTLHVMVEAVDEGPIVERRFVDITEADTARRCTRRXXXXXXXYAAANALGFPGGDDASGPYLVDDPLQRSDVRDHDRSRHRHVLVKLVRQGRLGSWGVRSCGTRQTSHAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH3</accession>
    <name>V6DWH3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurS</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit III</fullName>
            <shortName evidence="5">FGAR amidotransferase III</shortName>
            <shortName evidence="5">FGAR-AT III</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">purS</name>
        <name evidence="6" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PurS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078070.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117509at2157"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01926">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003850">
        <property type="entry name" value="PurS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34696">
        <property type="entry name" value="PTHR34696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02700">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00302">
        <property type="entry name" value="TIGR00302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="9271" checksum="4537E49F24969FC1" modified="2014-02-19" version="1">MTDYTATVTVRLKRGVLDPEAETTQQALERLGFELDDLRSADRFEVDLAAADADEAADRAGEMAERLLANPTIHDYDVRNNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH4</accession>
    <name>V6DWH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4531" checksum="0F1DE9E7214963BF" modified="2014-02-19" version="1">MRCGERKTRGTPTSKRVILNRPISTASVALDAGREHECHVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH5</accession>
    <name>V6DWH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3775" checksum="BA0D10E0735A83A4" modified="2014-02-19" version="1">MPSSDPFLAGGTNVFGSLRSAAQRHRELPNASGSTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH6</accession>
    <name>V6DWH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DegT/DnrJ/EryC1/StrS aminotransferase family protein</fullName>
            <ecNumber evidence="1">2.6.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Mrad2831_4614</name>
        <name evidence="1" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.90" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="11413" checksum="76E2931CE6913740" modified="2014-02-19" version="1">METPTEPPGAEHVYHLYVIAVPAADRDPLREHLGDAGIETGIHYPTPAYDHDPVVERLGERSLPATESVCRRIVSLPIHPRITDEEVDRVCTAVERYFEGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH7</accession>
    <name>V6DWH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12937" checksum="401F41031F67A7F9" modified="2014-02-19" version="1">MKSVVVVEVLEVPPRRSPGPDGPCDVRAAVLVEAQIRDVVRLGDRFGVSLAGVVDDQHLDRFVRLGADALDGRCEPVVPVVGRDDDRHERGGTRHRNRPSETRPDTSVPAPYRASPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH8</accession>
    <name>V6DWH8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_11179</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="2"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="16501" checksum="31D338C7E00AE050" modified="2014-02-19" version="1">MALFVDGPNVLREEFDVDLDDVRRAAEAEGPLVTTRLYLDEHATPGLIQAAEARGFEVVMTSGDVDVKLAVDAARFAAEGRMETLAIASRDTDFKPVVETANGYGIRTLAIAPGEFGRSDALRNAANGSVTLDGDESNVTEDSGETDTESAWHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWH9</accession>
    <name>V6DWH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thermosome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_09085</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="7308" checksum="30DD33B20423482D" modified="2014-02-19" version="1">MIDMEAEGVVEPLRVKTQAIESATEAAVMILRIDDVIAAGDLKGGGSDDGGDEGGPGGAPGGMGGGMGGMGGMGGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI0</accession>
    <name>V6DWI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase ISHwa3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_07104</name>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="14"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="20741" checksum="7C26E092190E4E84" modified="2014-02-19" version="1">MLLRQSAQLHDLSEHAAIDATFYERSAASRHYCQRISYRVQKLKVTKLVDTASQAVLDVHCSTNREGSDADLAEQIARRNAGDLRSLAADKGYDKQSLREGLRNLGIRPLIKHRIFAPYDHAHNARIDDNRYNQRSMTETVNSAVKRSLGFAVRAQSWFREFREIALMCMVYNIKRFVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI3</accession>
    <name>V6DWI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Group 1 glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C477_08908</name>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334958.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="203"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="374" mass="42657" checksum="3CA2133DBEA33852" modified="2014-02-19" version="1">MTQDSVAVLHDRFPTIGGSETFAIEAARVLDAPIFTMYVEPSLDVPSDVEIHAICQPKYTRGLSGRLLDWKNNGMNPFESASVAIDMTQGCDELIKYDVLLESGPLSKFYVPETHQRIVHYPHSPPRWLYDLFRDRMKRLDYPGIAFGARAYAKLWRALDKEAVDYVDTFVGNSELIRDRIRRYYGRDAEVVYPPVTGDWRNEGDDGYFLTWSRLDPEKRVDLIVEAFQGLDHRLVVAGDGQERQKLERMSEGHDNIEIRGFVEDIESLAAKATAVVYTPRQEDFGLVGAETLSAGKPLLGVDEGFTKNQVEEGVTGLLFDPSVESLRETVRAFDPSQFDRETIQSVAEQYRYETFEADLREVVFESERRFKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI4</accession>
    <name>V6DWI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_14063</name>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077698.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114723at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9642" checksum="717788F47ED8221E" modified="2014-02-19" version="1">MASESCDVCERSVRIAGGIGDLWNFAFESTQGLTLELTDGSEFFLCFDCMERLPDDHEPTAEDVADLRERTDPVEDDGNHFWHWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI5</accession>
    <name>V6DWI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide sugar dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_12820</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11792" checksum="52D21E68841F28FC" modified="2014-02-19" version="1">MGETLAEKDGHHDVVVKSTFVPGTTEDTLAPLLAETSSERLGEDLGVEINPEFLREGTAVADFLNLDKVVLGADNERTRETMPEIFESLVKHADNSPMSRLGRTRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI6</accession>
    <name>V6DWI6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">30S ribosomal protein S27e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rps27e</name>
        <name evidence="4" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077286.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129447at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_S27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_S27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="zinc finger region" description="C4-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="5814" checksum="4321815ED36E4AAB" modified="2014-02-19" version="1">MAGDFHRVACGDCENEQVVFGKASSTVSCAVCGTTLATPTGGEATLHGEIVETVEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI7</accession>
    <name>V6DWI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6638" checksum="6489A3EAEE9D65FD" modified="2014-02-19" version="1">MFRGRGGQEPARGICEHVHAGGSNARHLNRVGGSNPIGPTAGPADRSLARRTARFAVRPPNGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI8</accession>
    <name>V6DWI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C441_02807</name>
        <name evidence="8" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="185"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="35146" checksum="E0DF321CACCFBC7D" modified="2014-02-19" version="1">MIEVFVRSTVQIALVFVGLELFGLVAGALMGTAAAVGIGLYMIPVRIGAPRRKEALSLLSFAKFSFFREFATKAYHNIDTAVISVLIGNSAVGLYNIPFRIALVLQVFSSAVSTSSFPEISHHDDEGNYERIGEILGDAMVFSAIVAIPATVGIFLLAEQIVITLFTSAFAGGASVAVLAVAIEIPSGFRGTLTSAIDGMDRPELTLRADAVLIGTNLVLDLVLVPWIGIIGAAIASLAGVTASTVYLGYLFVEKLEMPLTVFQVQPLAMEVIAALVMGGVVYGLRETLAFPQPWNVLLLVGSGIATYSIVLPAISRDIRLRLIGIVRDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWI9</accession>
    <name>V6DWI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07064</name>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015888">
        <property type="term" value="P:thiamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005948">
        <property type="entry name" value="ThiB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01254">
        <property type="entry name" value="sfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="324" mass="35663" checksum="6F96688A67BD8A55" modified="2014-02-19" version="1">MSPGEWLKEEFESRYDAELEWATPDNEVNYYVERAASGAGIDADLYVGLTTEDLVRVDEQLDGDLFAERGAVDGFDDVREGLLFDPFDRAVPFDTGYVSLVYDGTTMEAPETFDGLLDDEHAGALIAQNPGGSSTGRAFLLHTISRFGDGGVASDGDGEAIEGEDGDADYDYLDYWADLQANDVRVLGDWDEAYTAWSNGEAPMVVSYSTDQVFADMEGQDLEKHQIRFLNDQAYANPEGMAVFADADEPDLARQFMSFMLEPDVQGEIAQRNVAFPATGNAELPSDYAELAQEPADPVTFTYDELQGSVDAWVEAWERQFAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ5</accession>
    <name>V6DWJ5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HFX_2194</name>
        <name evidence="7" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077702.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119451at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="6"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="20142" checksum="0E3901473F2AAF41" modified="2014-02-19" version="1">MPSTPLFAPDEFFSQQSPSLAGAAIILLFTGVVAVASAVPYADQLPFEVTLAALVLSVLIGGLIGAAGIWIVSTAVVYLLTAIVGGTGTVARTAANIGWASLPLLLMNAVSTLTLWALAFTGNAPAIEMTQMRLPSWLLIFNAITSLIGTVWLGYLLTYAIRDARNLDIRRSAGVAGIVVTILLLNTLVRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ6</accession>
    <name>V6DWJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5033" checksum="53A7D2C715B4055E" modified="2014-02-19" version="1">MPSTRVLGNSTIPTAPCHRSLHSDGFLTRLTPGGDLTEQTVKAASGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ7</accession>
    <name>V6DWJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
            <ecNumber evidence="2">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Natoc_3560</name>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="302" mass="33055" checksum="EDB8C6785EA4DE65" modified="2014-02-19" version="1">MVKNRHSMVRVLVTGSSGFIGMNLCTHLVEEGYEVHGADIEPPEFEHPSSVEERRVDLLSEPELPDVDVIVHLAAHSQVQSVVEDSNRAIENLKMTRHVLEEAVRMGADVVNASSRDVYGSAIRPSEDEVSPDSPNGYAASKLGGEALANAYAQNHDIRVVSLRLANVYGPKDTNRRVIPIFASRAAAGEKLKVFGEGKLLDFIHVDDVCDAIVAAMNRIDVADGESFNVGSGDGTPLKDVARMVSEIVDECPGWELDEDRSGDVSRYVSDNSKANSVLGFEPKKPIEEELEDTIKWYLDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWJ9</accession>
    <name>V6DWJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Brp-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07024</name>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022270">
        <property type="entry name" value="Blh_monoox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15461">
        <property type="entry name" value="BCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5103" checksum="95F0A4157FE30417" modified="2014-02-19" version="1">MGASVPAGVAAPGDLLAVSLVAIAAMTLPHVVVVAWLDRRQGVWRPGVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK0</accession>
    <name>V6DWK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_03489</name>
        <name evidence="1" type="ORF">BN903_132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077289.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92721at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004426">
        <property type="entry name" value="CHP00062"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00162">
        <property type="entry name" value="TIGR00162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="250" mass="26529" checksum="F0BCF60CAC138E57" modified="2014-02-19" version="1">MEDIEIDEVATPELDDPVLIEGLPGVGHVGKLAAEHLLEEFDGELVRRVYATEFPPQVSVDDEGVAELTCAEFHAVETDGADLLVLTGDHQAGSNAGHYRLTSTFLDIAEEFGSERAFALGGVPTGELVEEYTVLGAVSDAALVDDLEDAGVEFRADEPAGGIVGVSGLVLGLGGRRGFDAACLMGETSGYLVDPKSARAVLETLETVLGFSVDYESLEDRAEEMEEVVGKIQEMQEGPAVPDDDLRYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK2</accession>
    <name>V6DWK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_1494</name>
        <name evidence="1" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7882" checksum="93387AEEA1B2B711" modified="2014-02-19" version="1">MSMAEIDRLSERIAWIDLSFVERDRTPRWAVEVGIRCHLAGMSLREVSKFLEIFLDQPEPRCCSQLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK3</accession>
    <name>V6DWK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4610" checksum="3745850BC3F078B7" modified="2014-02-19" version="1">MGLLGADGTGGGVSRSRPLRVGRVPAVPLSDRRSFKRSPGHPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK4</accession>
    <name>V6DWK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysine biosynthesis protein LysW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysW</name>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005906">
        <property type="entry name" value="LysW"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01206">
        <property type="entry name" value="lysW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7916" checksum="47DC8D0B2F6E2924" modified="2014-02-19" version="1">MCSRRRERGTMTSDTDTLVAEDPITGEEIELPADVEVGEIIDSPVTGTELEVISLDPVVLEEAPELEEDWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK5</accession>
    <name>V6DWK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
            <ecNumber evidence="2">4.4.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14209</name>
        <name evidence="2" type="ORF">BN903_137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077293.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41173at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="129"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="251" mass="29082" checksum="A883C9D73A397E68" modified="2014-02-19" version="1">MDGTFDHVMIRVEDLEESLDWYQTHLNYEEKGRWEADTFTNVFLGPEDGALLELTYNHDGRSYEIGDAWGHIAVRVPEDALQESYDGLIEEGVDDYRDPESCGNRYAFVKDPDGHEIEIVKRDHGAKWSIDHTMIRVEDADEALGYWTRKFEYTEVPGRWEADTFSNYFVAPEDAPEEAMKLELTYNYDGREYTMGDGWGHVAVRVDDLDDAWDALLTREAPDYRDPASCDHNYAFTKDQDGHEVELVTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK6</accession>
    <name>V6DWK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase domain-containing protein</fullName>
            <ecNumber evidence="4">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C464_10948</name>
        <name evidence="4" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="3">
        <location>
            <begin position="155"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="399" mass="42988" checksum="0530BB55B52ACE92" modified="2014-02-19" version="1">MTDDGALRVGVVGVGSMGSHHARVYASSSAVDLVGVADTDRDRAAKIADKHGTRALDRETLLQAVDAVSVVVPTQFHAPIVREALEADTHVLVEKPFVADPAEGRELIDLADRNDLRLQVGHVERFNPAVRALVDVLPEMEVLAVDARRLGPPVDRENTDGVVEDLMIHDLDVLLSLFDAEVDEVFAAGIDGEPHVTSTLRLDNGVLGTVTASRVTHQKIRELAVTGRECRVSVDYLTQSVKIHRHSLPGYVESNGDVRYRSESVVERPQVNNGEPLRAELESFVSAVKTGSTPEVTGHDGIRAIELVRRIRDAVGGPRATVAGTGGRLTANAPVVGSSLRTVRRRRDARTNSGRRSETGGSPSRCTGWGRSDCRCRSCTPRRPVPSPASTSTPSGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWK7</accession>
    <name>V6DWK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11198" checksum="631CD57BCDBA2BBE" modified="2014-02-19" version="1">MVSWLATFFARTCPASSIAKPACMKKMRKQTTATHMRFTPSARTLGSIEASTALVTRRSPLLNARPIQNASCSDSCVESRLDSRERLYINVRVGFHKKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E053</accession>
    <name>V6E053_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7130" checksum="6C7BFDA55DC09E83" modified="2014-02-19" version="1">MSRFGIKRCGPSAFTISTIGENDIATLQLLCRMRDAIFRAGTAGSRSSVPASATAVATDPLVANAGCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E055</accession>
    <name>V6E055_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9094" checksum="F71D57639DDCAE86" modified="2014-02-19" version="1">MHVRPTDIEVVERVLELVERGADLDELLVGVGTADAGGATHRFFIQGEFGHGGVESVSSEPSFTARRDDGAPTVIGSFEQTLIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6E059</accession>
    <name>V6E059_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenic resistance protein ArsA</fullName>
            <ecNumber evidence="2">3.6.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_03100</name>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="318" mass="34729" checksum="4D18E9F59A0CA1B8" modified="2014-02-19" version="1">MADADAVVDQLTPGEETEYLFFTGKGGVGKSTVAATAATKLAEAGHETLVVTTDPAAHLEDIFGEPVGHEPTSVGQANLDAARIDQEKALAEYREQVLDHVTEMYEEKEDTEIDVDAAIANVEEELESPCAEEMAALEKFVSYFDEDGYDVVVFDTAPTGHTLRLLELPSDWKGFMDLGSLTKGAAPAKGDQYDEVIETMKDPERSTFAFVMYPEYTPMMEAYRAAADLNDQVGIETSLVVANYLLPEEYGDNAFFANRRAQQAQYLAEIRDRFDAPLMLAPLRRDEPIGLDELSAFGEEVTGLADVAEADAPEVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E073</accession>
    <name>V6E073_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_04406</name>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK40995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078352.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000025.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99073at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="17627" checksum="5DCE7917FB675DC1" modified="2014-02-19" version="1">MVPEMPTRRRKLLVSLSSAGLVSLAGCTDLGGDSTESDNDPTVVDTIEIANGQDVSRTFKVVLRSAESVLYWDSFELDASEDTNADVDLVEGPFGSGDEPLWLDVKAGYPDDDPDSGEGETVVTQPLGEEYSGCIYVVVFTRIAGGVSFRIDPANEIVSRDTRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E074</accession>
    <name>V6E074_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09568</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK40998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6584" checksum="AD8452CD66751A26" modified="2014-02-19" version="1">MTMPDTKSGRERKGRNKRRQLENHLARRELDADDEPPEPYAEPTDAEFLAESDDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E079</accession>
    <name>V6E079_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4490" checksum="EE65BF183F08A145" modified="2014-02-19" version="1">MVRDAFGVSSSRKSSIFERRRACGVLAAGASWVFVAVSISDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E080</accession>
    <name>V6E080_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5721" checksum="1FCF76058FB839BE" modified="2014-02-19" version="1">MVHAGDTFPRHESLAPDIPNSGGFINPNSTAVSREIPGFNGSRNRFKRIAFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6E082</accession>
    <name>V6E082_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Threonine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_09643</name>
        <name evidence="3" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04886">
        <property type="entry name" value="ACT_ThrD-II-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044561">
        <property type="entry name" value="ACT_ThrD-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="78"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="273" mass="29303" checksum="398124BCE7BC844F" modified="2014-02-19" version="1">MSDDDVANAILLLLERAKQMVEGAGATAAAALLNDDAVDELDLTGETVVPLLCGGNIDVTTLKEVVTHALVDRHQLIELAVRIDDTPGTMGEISTLIGGERANIRTVRHERSRPDLPVGDADLVFEVETNGPAHVDRVLRAVREAGYEVEWTTRRGEEPCRLLINGHGGGAPVERRTAARTAREGVGRDEGDRREPDGRGRRGWGGMRLCGAVGWDSKGQSARRAQATQGPQGVSEANDRGPQRVCARLADWGFGSISVSPLKFISGSADRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E085</accession>
    <name>V6E085_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="250" mass="27509" checksum="E682F0F776606338" modified="2014-02-19" version="1">MVVFRVFARGGLAHAVRLPEREVRRVALLGALVRFALRFERVGLLVRELPVPVEARHVEVDGAVRLVGVPLFDQRLHEVEYLRDVLGDAGVHLGAQQVQPAHRVEDARGERLGHVALFGPVVALADTGRDLLVDVGDVLDVTHVVADVFEPPMEDIGVEPQPGVTEVGVVRHRQSTDVQRDVAVGRELDALVFQGVGNDETHYEVVARVSVSNRRIKQTEAGCSPDLFIQKLRGRVSSRLGPLRIRAPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6E089</accession>
    <name>V6E089_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA photolyase FAD-binding protein</fullName>
            <ecNumber evidence="8">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_04326</name>
        <name evidence="8" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078359.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000025.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21461at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK41013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="461" mass="52546" checksum="4CE6D86AF5DB287D" modified="2014-02-19" version="1">MELFWHRGDARTRDNAGLAAAAREGEVVPVFVYDADLLATVGARQRAFFLRHVKRLEERYQALGSDLIVRAGDPDEVLVDLAAEYDAETVFHNEHYRAARRNRQRAVEEALAAAGVETDSRTDLVMVDPGRLEARYANHSRFHDDWETVPKRRPYAEPDPEALADVRDGKTVPEPDADVDLPEAGYEAARERFDEFLDYGITSYNDTRDDLARAVDAPTHAVSRMSPYLATGAIGIRELWAGASDVYDAVTGGERRNVDKYRYELSWREQMYHLLYYTPDLAVSNYKSFPNEIAWRDDDAGFEAWTRGETGYPLVDAGMRQLNAEGYIHNRPRQVVASFLTKHLLIDWRRGARYFTKQLIDHDYASNHGAWQWTASTGTDSVDVRIFDPVSQMSKYDADARFVKAYVPELSDVPAGKVVDWPTLSRTERESLAPDYPHPIVDRNEGYERAQRVFEEALGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E090</accession>
    <name>V6E090_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6511" checksum="AD9CAA2F2C56F003" modified="2014-02-19" version="1">MRRPRGWGFGGVRVDPSFINKTPVQPSGWGFGSVRVDRRFIRDRYASPSGWGFGSGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6E093</accession>
    <name>V6E093_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S19e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rps19e</name>
        <name evidence="5" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in maturation of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078366.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000026.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92409at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01474">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_S19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027548">
        <property type="entry name" value="Ribosomal_S19e_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018277">
        <property type="entry name" value="Ribosomal_S19e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="PTHR11710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00628">
        <property type="entry name" value="RIBOSOMAL_S19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK41018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16887" checksum="8BFC39828055EF43" modified="2014-02-19" version="1">MVTIYDVPADDLIEAVAARLEDRIDEPDWVEFTKSGAGKELPPEQEDFWYVRSASLLRKVAQNEPVGIERLATEYGSKKRGSNRYSVRPGEHEGGSRNLIRTALQALEEEGLVTTAAGEGRRVSDEGEAFLSEVATEVFEDLDRPELERYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6E094</accession>
    <name>V6E094_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_13420</name>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078361.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000025.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89551at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="38"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="17676" checksum="222E123B61BF7AA1" modified="2014-02-19" version="1">MERVAIDDVDVVTNPMGVHDLRKPVSRALGTEHVAMNYFELAPGDAFSGGLHTHGDQEEIFYVLSGTATFEVGRERERVEVGPGELIRFAPGEFQSGFVPEDAGEEVVAWAVGAPGARHDFEEIESIVECRECGGERIHDTELTDAGRFRFTCTDCGASFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E098</accession>
    <name>V6E098_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4336" checksum="AF94AA99A9377CAA" modified="2014-02-19" version="1">MRLFRHIGGDSRRAQKRTGRRAGNTLETEFDIAKYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E099</accession>
    <name>V6E099_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18632" checksum="70A58EC965C8C808" modified="2014-02-19" version="1">MVESNVIRRVGDERVRKRAIVSETERSRRRREREPSDVPVGSDDDRQFVVGERVAAEVGDPEIGPLGVELRGRHRIRIRDRPVEEGGPERGSHKEKHRYEEDRPRGARLGTSAGRREHRESAGCADLTGVVHYSPHPSINCDNCTEGEAKGGGGRTVTDRSHPRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNP2</accession>
    <name>V6DNP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C460_02974</name>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="10554" checksum="A1BF1A52C724D15D" modified="2014-02-19" version="1">MSRQLDRLRLAVVLNDAEIFQLREVRLDERGVDALAASLRRRALARLADRLARIASGPLPKPIPYLLAVGITLGVLWMGSRLAYGGTLTRALFGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNP6</accession>
    <name>V6DNP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_15047</name>
        <name evidence="7" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73309at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK37879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="356" mass="37132" checksum="22B1E2BC714FF63A" modified="2014-02-19" version="1">MVSPSLATTLLQASADGSSPGRFSPVESLWRLFEWLLVDVYGTGMNLLAELLGVRMLGYPYMQRAYLAAICIAVIGPLVGTFLVHRELSMLADTLAHTAFAGVAVGLFLNAALSLSLSPLLTAMIVAVGTALLVELLIDYAGAYSDTSLAIVLTTGFALGSVLITATDGGIAVGIDAYLFGSLSTVSKDNVGLLVAMSLLIGTLVTVAYRPLLYVTVDATAARAARINVRLYKRLMVVLTAFVVVSAMQIMGVILVAAMLVVPVATAGFVARSFKQSILLAILAAEFAVLSGVTLAYVYGIAAGGSIVISAAAVYATVLVVAKVDIRWVLRLLPTRSGPSVERAEQGLEADGGERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNP7</accession>
    <name>V6DNP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transporters inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_14967</name>
        <name evidence="6" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075803.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68860at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="89"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK37862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="30118" checksum="72A299593B9F73E2" modified="2014-02-19" version="1">MSTRTDTRSDTSVAYGFEGNLRRYLRGLGGLIVFLLVWWVGAMLTQPSYLVPSPLDSVRAFIDLFATTTAIVVPVSGSSLVLPTGLAHLTETLFHYVPGLLLGAGGGIGLGLLMGWNGALDDWLRPLVRVLRPIPPLAWIVFAIVWFGIHHTGAAFIVFIGAFWINFYAAYGGVEGVAGDLTDAASTLGVERDLSMLKLVALPSAAPQVLTGFRTSIGRCWMIVVGAELFGAPGVGYEIINASNNLAMATSVAYMFLISLAFLCMDIGFRLFEGRVLAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNR2</accession>
    <name>V6DNR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C453_00765</name>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123727at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8038" checksum="553FE983149AB912" modified="2014-02-19" version="1">MNNTDPDSTCPSWNGTEAPGPSDHQRPELLALVVRSTDEPTCTIYPPDVAAPYRSTTWISASGDDFVRLEQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNR3</accession>
    <name>V6DNR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription initiation factor IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tfb</name>
        <name evidence="5" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIB" evidence="4">
        <location>
            <begin position="90"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK37894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="202" mass="22313" checksum="B09800D2678A8970" modified="2014-02-19" version="1">MDAVCDDCGLVVPDATLDTSITLYTSSGTDGQESHVGAPSTNLLHDKGLSTIIGWQNTDLNGNTLPGKRRQQMRRLRRWDERFRRRSSSDKNLIYAFGETNRMASALGVPQSTRETAGIIYRRALGDGLLPSRAVESVGTAALNAASRMDDAPRSIDEVSTVSRVEQIRVERAYRHVSRELGLEIVPIDPRSFMLNSVHIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNR4</accession>
    <name>V6DNR4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C436_05786</name>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075776.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97867at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="128" mass="14834" checksum="6E3EE2D1031C8041" modified="2014-02-19" version="1">MDARTTITEYYEALRAGEPLDPFFAVERPDDNDYVKFGISEQLVGRDQIRTGLRSQTETTTDWNVTSSALRVTQCDTCAWFSDVVSMAWTNTETEHRHDFETRWSGTLRRSDDRWQFVGMHVSTADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNR7</accession>
    <name>V6DNR7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pilin_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">D320_10289</name>
        <name evidence="3" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012859">
        <property type="entry name" value="Pilin_N_archaeal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07790">
        <property type="entry name" value="Pilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Pilin_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="195" mass="21030" checksum="BA555D99CEF4AB9F" modified="2014-02-19" version="1">MVMNQQDRAVTPVVSTILMVAIVVILAATVSVFALGFVENINEPAPQVAQTTGEFVIGPNDQAVKVNHIGGNYVEVKNIEIIVRASGSGVNKKERLINLPSTGHSISSANLKQDNGLIAKGYGDAGDDDPNQVIIEDYPTDNNRWEAGETIRFEINSGENGADFREGESPHADELEVVIVHTESNAIISEHVFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNR9</accession>
    <name>V6DNR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C465_01739</name>
        <name evidence="4" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62627at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="196"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK37899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="249" mass="28804" checksum="7851564C4FEC7561" modified="2014-02-19" version="1">MTGNSTTVEEMREFEFVLQFESGADELMDIFRQHEKLSLWSSAIFINDNNMWRLDHAKGTKEALSAFDKVFLDETRCNECFDVSGCATERAYKVLDQQETSRTIYTLRQEIEECYSLPHFVFDHVQKGTVFESRRIGNEYRWRVLFPGGCPIGDVYDTMESHLRDGVSLSVSHLTSAGNWDATERVATNFSTEHWQVLKTAVDHGYYNRPREVSVADLASILDEPRSTVQYRLRTAEDRILSQFVKQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNS2</accession>
    <name>V6DNS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioredoxin reductase-like protein</fullName>
            <ecNumber evidence="1">1.18.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15082</name>
        <name evidence="1" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075825.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61760at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="385" mass="42343" checksum="2E4AF409F9460C0C" modified="2014-02-19" version="1">MASTNLRKCESLDAVIVGAGAAGVGTGVILEDLGLDSYAILDREAVGASFRQWPDEMRLITPSFPSNSFGCRDLNAVTTDTSPAFALDSEHPSGEAYAEYLDGVVEFYDLPVRTGVDVESVQRHDDEFVLHTSSGPIQSRFVVWATGQFGRPNDEPFPGASHCVHNTRVGSWSSFADECVDDPVVVVGGYESGIDAALALADAGRETIVLDEEGPWRFRGPDPSEVLSPYTSQRLREAFERHAPITLEDGVRVERVERAESDNESFEVVSKDGETFATRNRPVLATGFQSGLGPADEHFAFDDSRPELTDRDESTTTPGVFLVGPQVSHNGQLFCFIYKFRQRFAVVADEIAARLDIDRTPLEEYREKDMFLEDLSCCEPDMCDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNS4</accession>
    <name>V6DNS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_08265</name>
        <name evidence="3" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7688" checksum="8EAE24B0FB101391" modified="2014-02-19" version="1">MTREVETVSPDKTVATVARRMADSDGHAGFPITQSRTVKGFVSAGNLLLADDDTPAFTVMTKDQIVAHPTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNS6</accession>
    <name>V6DNS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sodium-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15117</name>
        <name evidence="3" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075782.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="52466at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="500" mass="52483" checksum="731F88FB3B7F5D98" modified="2014-02-19" version="1">MRLQQLFKSQSELDLTDGPIPRALFFLSFPIVITNLLQVGYNLADTFWLGRYSTEALAAISLGFPLVYLFISLGLGLTVAGSVLVAQHTGAEQPAKAEYAASQAVIFTLLAGIILGALGYSFVAELLGVFDAEPVVLGLATEYMEVISLGLPFLFGFTIFIALMRGAGDTVTPMLVMLGTVILNVALDPLLIFGVGPLPELGVEGAAVATVFARGSAMVVGIWLMLRGAHGIQIHLRQMVPDLSYSRKLLRIGVPASIENTGRAISINAVLVIVTLFSTSVVAAFGVGIRVFSMIFMPAIAIDRGVEAMTGQNIGAGRHDRVVATNRFAAKVSFLLFSAVGLATFVFAPEIIGIFDNSPAVVAEGASFLRWIALTFGFVGVIRAYSGGFRGAGKTLTAATIAVVLFGFIRLPIAYVASQGLVPIDGWFFVTPSPTGIWFAFAVSSVIAAVVAAGWFESGGWRGGDLTDEAMEASNTSAADEDSSVDGGAGEESDVISGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNS8</accession>
    <name>V6DNS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hmuk_1138</name>
        <name evidence="1" type="ORF">BN903_16</name>
        <name evidence="2" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4805" checksum="282D903C27B71E24" modified="2014-02-19" version="1">MPECAHCGGHVSQRFVTVFGLDGGDVVACPACSSQANIAETVLDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNT1</accession>
    <name>V6DNT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ISH9-type transposase ISHwa3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08880</name>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5295" checksum="0AE3CEF293D7391C" modified="2014-02-19" version="1">MTETVKLAVKRSLGFAIRTRLWFREFREIVLVCLVCKIEHFVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNU2</accession>
    <name>V6DNU2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C461_10196</name>
        <name evidence="6" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075789.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80607at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK37836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="346" mass="35488" checksum="69F09B25E2CE052B" modified="2014-02-19" version="1">MFEIVPGFELLGLSGELLALFVAFGFMVGVFFGFFGMGGSFLVTPALLILGYPAPVAIGSSMTFVFGTAVIATMKHHDAGQVDYKLGALMFVGIAAGIELGSRLVFGLEVLGIANVVVGVAYVLLLAAIGVLFTRSALDNDQDAGTTADEPTDGGADDEVPEIAQKIKSYDIPPMMTLADGSKASLWTISGVGGGVGLVSGFLGVGGGFVRMPAIYYVIGTSLAAAVGTSLFGGLLSGAVGAFTYGRAGVIDLGIVTALLVGSALGARIGSSATAYVDEDDVTIYFGIMLLVASLAVGLGELAEWLSMPILDQLSFVLLIGSALFVCLMILYHGTLAVRRTRNVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNU3</accession>
    <name>V6DNU3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulf_transp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C464_00774</name>
        <name evidence="8" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075839.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108031at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="7">
        <location>
            <begin position="20"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="18817" checksum="3BB22993C71807E8" modified="2014-02-19" version="1">MATSLVLLQSVAELFPNGISRYAVGGLLVGLGTVVIYVGTGIPAGASTFLESTLSYVSGQSRFQQYVGSRDWRLVFTAGIILGAFAFAATVQSGVVTTSLYEPGTTGQLYEVAGVTLWSTDVQPWRLFFGGILVGIGTRVGKGCTSGHGVCGVGSASKTSLVGVATFLTVAIGTAQVVAALGVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNU4</accession>
    <name>V6DNU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_08265</name>
        <name evidence="1" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4579" checksum="53A523A69DE5EB31" modified="2014-02-19" version="1">MIVPRTPVELGMAKTAQKEGLRVVESVEIVDSITVDLIAAVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNU7</accession>
    <name>V6DNU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_03614</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10251" checksum="9FF50B3A790ADF33" modified="2014-02-19" version="1">MSCEKRRVFGAGFVLLQGVVTAVFPQLSVKLAKKMIGKNFDNASDLEANPAYVRQLRAVGVGMVAAGGTTLLLDSPQETKSDSPEDGASDEGSTESST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRX1</accession>
    <name>V6DRX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4730" checksum="4426B398862B77D8" modified="2014-02-19" version="1">MAGSGGERGVVGVSRVGTTGGRGGGFDRGRFSLKRSLALFRLSFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRX3</accession>
    <name>V6DRX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6930" checksum="EBB654FF06CEB179" modified="2014-02-19" version="1">MVFVANPAVTAYNRAVAARLSVTKSSTKSGSATPYSAYRKRVGGARLRPGFPYTRFHALAQPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRX5</accession>
    <name>V6DRX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="8168" checksum="8A54AEA61FED042E" modified="2014-02-19" version="1">MILDVLEGGVDLVCEFGLGCRAVVERREDRPGGLGAEGGDEVVGLVVVDADDPRFALLGRRIRQGGQQPGHVLLWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRX7</accession>
    <name>V6DRX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4086" checksum="9CAF4546016E0BFF" modified="2014-02-19" version="1">MGTCNPTPVTCGDGIRILGLTKLYTNSVWNLRYVGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRZ0</accession>
    <name>V6DRZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PaaX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C484_18702</name>
        <name evidence="2" type="ORF">BN903_168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075865.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107911at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="150" mass="16756" checksum="CE01DFE8849B9608" modified="2014-02-19" version="1">MPIDLRTHDPSDDIHIDPSTNKAAIIQLLYTNPNYGFTPSEIHDQLDDIPKGSITGTLTRLFNDGDIGKTADGYYHALKSRDDLRRFARGLVQVRDLTVRYDDDFSPADIEQTDESSPSGAQSEIRQDSSANDEPTPEDWIESTDDSEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRZ3</accession>
    <name>V6DRZ3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0212 protein BN903_253</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04483</name>
        <name evidence="2" type="ORF">BN903_253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0212 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01223">
        <property type="entry name" value="UPF0212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007564">
        <property type="entry name" value="UPF0212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42199">
        <property type="entry name" value="PTHR42199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04475">
        <property type="entry name" value="DUF555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016934">
        <property type="entry name" value="UCP016934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12065" checksum="78EEBC1B812C6500" modified="2014-02-19" version="1">MVRDVEETDDAIGVAVSEAGKRLNETDKQYVEVEPGVTGCPACGEPFDAAFLAANTALVGLLLEIDVFNADSEEHAERIAKSEVGGALRDVPLEVIDVFETEADDEDEEPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRZ5</accession>
    <name>V6DRZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4986" checksum="1E5D0CFEE4071A3A" modified="2014-02-19" version="1">MRQDSGSEATDRNYSRNADQAFRRRVRGRDVTVVVPGSDRCSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRZ6</accession>
    <name>V6DRZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycolate phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_13542</name>
        <name evidence="1" type="ORF">BN903_235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="7919" checksum="4BD2CAFC36307284" modified="2014-02-19" version="1">MSKGRALEVVADALGLDPAAFVAVGDRENDVSTFGVAGESYAVANADDAAREAADTVLDVGYMDGTEAVLSALRERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRZ7</accession>
    <name>V6DRZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5185" checksum="CC5DB04D45EB5DE1" modified="2014-02-19" version="1">MMSVIASRQDGRVLNGLDDRKIGVDRQSRAIRTASERSHDCGDVNTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRZ8</accession>
    <name>V6DRZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetolactate synthase large subunit</fullName>
            <ecNumber evidence="4">2.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C471_13963</name>
        <name evidence="4" type="ORF">BN903_258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_M" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="3">
        <location>
            <begin position="130"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="311" mass="34165" checksum="3BB280D52CB1BB1C" modified="2014-02-19" version="1">MHGTGYANLAITHTDCLIAVGTRFDDRLTGGIDTFAPEAEVIHVDMDPAEISKNVYADYPLIGDAGRVLDQLTAAVREAPDAEAWRERCAEWKETYPLTYATPDDEPLKPQFVVEAFDEATDDDTIVTTGVGQHQMWASQFWSYSEPRTWVSSHGLGTMGYGVPAAVGARVAADTMGEPDRDVVCFDGDGSFLMTMQELSVAVREELDITVAVLNNEYIGMVRQWQDAFYEGRHMASEYSWMPEFDKLAEAFGALGLRVDDYDEVAPAVEEGLDYDGPAVIDFHVDPEENVLPMVPSGGANGKFAAVEDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS91</accession>
    <name>V6DS91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_08755</name>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076798.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62124at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="274" mass="29171" checksum="EC30CF34CA4A4706" modified="2014-02-19" version="1">MNVPNDFDVDDKVCVITGGSGVLGSEMARALGENGATIVILARGEEKLRETGEELAAAGIEHHTVSASVLDRTELEAAAETVIAEYGRIDVLINAAGGNSAEATTGPDTSFFDLPVEGFQQVLNVNFTGTVLASQVFGEYMVEEGTGCILNVSSMNAYTPLTKIPAYSGAKAAVSNFTEWLAVHMAHNYSTDIRVNAIAPGFFLTEQNRYLLIDEETGEYTDRGQTIIDHTPQDRFGRPEDLSTTVLWLVSPGAEFVHGASIPIDGGFSAFSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS92</accession>
    <name>V6DS92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6016" checksum="F1BABFA8450A5322" modified="2014-02-19" version="1">MNPRTQGTVSSPKFFRDIDEPTTFTGVQGENLALQRGEDVKLAVTRIYSIAVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS93</accession>
    <name>V6DS93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5559" checksum="5FD2DEEE91EC26D0" modified="2014-02-19" version="1">MRAHDWIAGSGGSDLVVRFDLVEPDTLRTFALVIVVYSSFYWLSLPRAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS95</accession>
    <name>V6DS95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075956.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="143422at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="219" mass="24656" checksum="0BA25B0B46489D81" modified="2014-02-19" version="1">MSFIDTEDHEHATLIETRHNRLATEHGRDNVFITEINGEVVTLIGDGVGTVDPLDVSVTKLTDGIEHDGHRVEPALVPLFEEPVPWFEGHHDLFELAAGRTGRVCTLSPDGILFLDFGARRFYEDRIERYETAEAVDGVPIVASEDEALANEKHSTWLSIDDTSVWTYEYVPFIDPVQTTAQLQTQLNRILETPPEWDALFESTTDIFERELAGEHAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS96</accession>
    <name>V6DS96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">6-phosphogluconolactonase</fullName>
            <ecNumber evidence="1">3.1.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_08735</name>
        <name evidence="1" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="320" mass="34064" checksum="A4D954C8D42B2913" modified="2014-02-19" version="1">MRQLDAVAAGPDPTFVTFGPSGEYLYVAVREEGEGVIRSYAVDRDTGELTERDSAPSGAAAPCYCSVDKTGRCLLVAHYAGGAVSMLSLDADSGVGSPVETIDHRGSSVDSDRQTAPHPHSITLGPEDRFAYVPDLGTDQLHTYVIECDEPSLSRVEAVDLSPGSGPRHLSFAPGGERAYLINELDSTVTVLNRESDGTLTERASVSTLPAEFEGDNKTAEIAVHPSGKYVYGSNRGLDSIATFEVDGEEIEQVDQTATGGEWPRHFAIAPDGALLFAENRHTDDIVAFDVDSQTGGLTPTGESLSVSEPVCMQWLPDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS98</accession>
    <name>V6DS98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6940" checksum="4CCEE91A28FEB1A6" modified="2014-02-19" version="1">MTVLPVWPSDWRYSRVWMTEPPFGQRRIPPTGISSFSVLPVNLLFGHREGEISRFCCSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS99</accession>
    <name>V6DS99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075959.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10257" checksum="F72918A4DC5915D8" modified="2014-02-19" version="1">MSDSSSDRPLDVSVKRLNSRYSDELKDSEIVLREIPGTPRYRLVIEPVDPSEHDHDFQKDLGETFDKAGMRAFIAGLEAAPLIAQRAESAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA0</accession>
    <name>V6DWA0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1863 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_08720</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036490">
        <property type="entry name" value="MTH538_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52206">
        <property type="entry name" value="SSF52206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1863" evidence="1">
        <location>
            <begin position="4"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="16079" checksum="17B5AF65662B5CB6" modified="2014-02-19" version="1">MTHDNREGAGYIDAAEWEEIKRGGEDAIERWIDEQIHNTSVTVVLIGSETYNRDWVNREIEKSYNQGNGLLGIYIHNIEDKNGRTARNGKNPLDKWHITEKGRKKYLSDIFETYHWKRDDGYNNLGGWVEKAAQLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA1</accession>
    <name>V6DWA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11145</name>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077226.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="335" mass="36781" checksum="B73029452FCBA138" modified="2014-02-19" version="1">MSAQSNTQQAAQGGSETIGEVAGDVVEEGSFHVPESIVDEAVWAAYLNTDDGRRVPCSGISAKPRYINSHDPEEKHLVNFEEALANVEESRREFPHDEALDGTMLILGAQDGLSCIDLDGVVSDDGELDELATDILGDLGGSTYAEVSPSGSGCHLILRDSEGLDDDYTIKGEIETYNNRGVSFSGRRVQSSLTEIAEMDGMMSAYQHIYNSERDSDDIEAESDDGDDIDYEPQGSLSDKNQELVDAMTSHDDTAEDLYERGDSMSLAQFGNDRSRGDMSLASKICWWADEAGMLSHHDYTESDIISVFMSSDLARRTKVQTRPDYVRMTVRKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA2</accession>
    <name>V6DWA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4396" checksum="B596279666EA1F15" modified="2014-02-19" version="1">MVNHPLNSVQYRGATERSVQILHLPESVTDSSHVRPPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA3</accession>
    <name>V6DWA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4501" checksum="1D433F2F44702203" modified="2014-02-19" version="1">MWEVSYRKTNALREDVRGIGFRLVLGSISEEIAGHTRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA4</accession>
    <name>V6DWA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_14271</name>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077635.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99527at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043927">
        <property type="entry name" value="DUF5778"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19090">
        <property type="entry name" value="DUF5778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14646" checksum="3155B638B3A8C250" modified="2014-02-19" version="1">MSETVDSDLYTRTKALLEPGDIELLGCIVHTTLDGQQDLEMHELTVAANEVIADHAGKGETYIEAGNDDTDFSSNQFQGLTLDDEAFVWECQQLLRDGAFDIVFYYEANVDQEALVADLAELDDVDRVTQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA5</accession>
    <name>V6DWA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HLRTI_08535</name>
        <name evidence="3" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078030.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58586at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="454" mass="50845" checksum="54EBD5927F944137" modified="2014-02-19" version="1">MAVLDDLSGFEFEDLIEDVFRNLGYENVHQAEKTADEGRDVIMEEVVDGTRRAVIVECKHTATVGRPVVQKLHSAISTFHFDGPKRGMVVTTGRFTSPAREYAGRLQQNDDPYPIELLDGQDLREIADEIGLDLYNGRIEILCDETLRPYDPAADVDAPVVEAFRDIENIEVADLPDPYSAVTFRPVVAVTADTNAVFETSVGVIHRINDRTQFVVHAERGTPQVVGEDVATLVTENLHTRIELDSGQFGEVFDDVEEHRFGQTQTEYKEWAVERLQDHHTTSVTYTGDNNVTYNKTCEPNRSDISVQSIEPVYLPEVRHTTDIQEYTYPYEYYAAGPSRVTTEDGIHRCVHCEASGVDETYTYCPNCGAIACDSHIKTERLDQEPVCTGCAVTERFALKTKYFYDEENVEAFREEYAAMPLHEKAMENKILAGGSVVATLLLVVGLLVISGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA6</accession>
    <name>V6DWA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4146" checksum="12C739C29445EA32" modified="2014-02-19" version="1">MGDIYTCRTHETLATLEVVVLSLTSAKVEPTDLLVNPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA7</accession>
    <name>V6DWA7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH dtxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C462_00052</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107911at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="15867" checksum="15C1BB5E65F1C08A" modified="2014-02-19" version="1">MDIEEFERVEDGGSDLSTSEAIVKFLLENSEQAWKRGEIAEKINRDPNTVGTNLSRLKERGLVRHRKNHWAITDNHHQLVEAVRFSNTLSTLNETVGPLIESEEEAKAWSNAQPERTHRSVSDGDEAAETIENGVDNGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA8</accession>
    <name>V6DWA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="420" mass="45676" checksum="39828317FC39FA49" modified="2014-02-19" version="1">MFPAGVADRPVDHREDHVVAVGGVHQMREGVVERRRPGQVGRDPDHVGALTLPEGSEPVETGRASAALRRHLQYGRRREPRGVPGVDLTEEARLSHLGEGVERVVTRGAVVAERDRNLPVEVVLDRRDPRGEFHVRGGAVGDDRVRLGEHLPFALVRVDAVRERHVRAGDPDLVEPEHVPPAGVGLHRLDLVLVLAGVGVDRHAVVPVGQLATAAQARLGTGDREPRRDRVPDASVGRAVVLPNEGLALRERRVGLLQEAVRRVAVHQHLPEPGADPGVDRGLERLRGVVHGEVVDDGRRPRFETLQVAQLRGRPRRLGVHRRLHRQHGVEQPVQQRGVVSDPPAQRLDGVNVAADEPRRDDVELAALVVGVPLAEVGLVADRGDRFPLDDDSAVGDDGLRVGDDCSGDQHVRPFLSVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWA9</accession>
    <name>V6DWA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hmuk_0961</name>
        <name evidence="1" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="289" mass="31910" checksum="3469CC86DEC45153" modified="2014-02-19" version="1">MGINPVYATVTQIKIGNRDDFGTGFFYNFLDETYLITNKHLLAPSDAENANEIIFFIRSYNQLRNISWITVSLEDGIGEDWFEYTSNKALDYDVDIAVIPINQRLSDFSEKINTSNPSVETGSLAFTPEMILQGDGIVSGGDVVLVVGYPDGLLDSNTYIPLLRDARISTPFGLAFQQQPKFITDAMMYPGMSGSPIVAGPRTLKNPATGGLRTSSRGFALLGIHSGNYERADGDRMERLNLNAGWYAKLINIIILNILLKDTDDEEELIERIGSVVSLDVKPTTPLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC0</accession>
    <name>V6DWC0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_H_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_16788</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078040.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69069at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="1">
        <location>
            <begin position="67"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="24356" checksum="5C7F4119AE6E109A" modified="2014-02-19" version="1">MTELTTIAFDIETTGFGADDKLTVVGFDSPVSSRVFLNTGGSTPTTGLAEQVNNTLQTPVQLSFHDSEQELLTELATFVTSTLTQRDAKLVAYNGERWNGGFDLPFLRTRFCTHGLEWPFGMLPYVDVMDVFEKRFNTSEDSLSGVYGELVGAGLNDVDPFADSGEAVTVWEEGAYEPLITHNVADIRRTRALMELAERYCSKSDFSMKSLEPIESGRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC2</accession>
    <name>V6DWC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C437_14954</name>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="480" mass="53915" checksum="DDF96D1D6260390B" modified="2014-02-19" version="1">MKGTKRFLIKSGTGSNLSEADSDYTIVIDDYRTKTETEGSRLIKYEKKVLSNLFGQSPPPTVTALVELALGTYAADRLVKRGPTGAKDDGEEMLKSRQIQILYPVVDVKKWQPLESELNHAVSFISRDNFQYRFIDAIDENQSVNENDGMPRGQLPEADSVALFSGGLDSLGGRFHLADEGHNPHFVSVDHGRNVGHLVRNFDHLFDANLTSIGVDEGFSAYENTQFTRSFMYFAFAAAVAVALDVDDIYVPENGVLSRFSSLETGWTTTRTVHPLFIKSLNRIFEELLPDRQVKISNPFINYTKGEVVNCIPNKEDIFFTRTCPHPRELSQGKDAVGHPYNCGECIPCLIRIIGLVNSEHDIQPDRLLLDKNHFIDLDFSTVSTKTIAQSDQNRQSSLSVFLLGLNAQLSFAYRIQTSTQKELVSSNPELLDPDIYGLYERFSKEMFRTVEFFAAENPTLEDYVTEFLSLDEGELVSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC3</accession>
    <name>V6DWC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine triad (HIT) protein</fullName>
            <ecNumber evidence="4">2.7.7.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C469_11311</name>
        <name evidence="4" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.53" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077647.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93754at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HIT" evidence="3">
        <location>
            <begin position="24"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2">
        <location>
            <begin position="119"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="188" mass="20497" checksum="F6CB0D79C2519970" modified="2014-02-19" version="1">MERIYAPWRIEWVERDADPIEGCPFCVLPERDDDREAWIVAYSDRNYVLLNNAPYNPGHAMVIPNDHHEDPTDLDDATLLDHAKLKAATLSAMRRDVDPDGVNTGQNLGDSAAGGSIDHLHTHVVPRWNGDTNFMPVTGGTKVIVEAIDRTYGHLHAGFAAGDDVVDAGDADAGEAVRLSFDLGVDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC4</accession>
    <name>V6DWC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11080</name>
        <name evidence="1" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="14717" checksum="B9780F7C7AEFF7A2" modified="2014-02-19" version="1">MRITDAILSLLMAFLHDEGELLVLDNAFNGRDVEVGLFDDTVDAIAEGDSYAAISTEPDGADYAVQSVTGPTVTQDAGTTSVEMGALSYNVSDATTSVNYVYVRDATSGDLIFTNALDQSYDLGSIDTLDLSNVGMELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC5</accession>
    <name>V6DWC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Orc1-type DNA replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_02221</name>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078045.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="50722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="39"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="341" mass="38685" checksum="8C43E1132353EA68" modified="2014-02-19" version="1">MIRDARVLRAGFVPREVEHRDAEVNHLSSVLEPITNGEPADTAIVTGPSGVGKTCVSKFVTERLREEVLDVEATYVNCWRNYSRFRTLYQILDDIGATIDIHRQSTPHDELIDRLQQYDGPRTVVILDEVDQLEDPSVIYDLHSLPQFAVVCIANKEEELFSRVDDRLVSRLRSSEHVRMDKYHNEQLYDILSARTKWGLEDDVISDEQLYQIADAAAGDARLAIGMLRSAASTADRENCDRITDDNLVDAAEDARAQIKQKSLDSLTPHQRVVYDVVRDHGPLGPSEIHERYTEEVDDPRTKRTVRTYLSKMAQYNLLEAEGTSRDREYSLVDAAAASPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC6</accession>
    <name>V6DWC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="377" mass="40515" checksum="E56D9F580B70BCE2" modified="2014-02-19" version="1">MSFDTIFVPAFGSDASRILEIDNETGDTVAFHSVSDSVGGIDRDADGNVYAIVGQYLKKYSPDMNLIWTSGETYSTTVVEVADNGNAIFVGGGSRIIRLDPDGSIVWNSYDTNIGCLDMSYDGGDYLYVQAADDSEDRRYGFANGNDSAEELVGYNDDSSGILHHNGSLYSTELTTSNLWRSDTFVEGSTINDGNFTVSNYTNLDMDRGGLYTAGSGGKIAHLDFDGNTQWEVSISGSPYFVGIDVSPDTLWASSDAGLYRIDKSDGSVLWKNTDTQFNSTAHESLGGFPNLDSYGGANWEVTVQISGTATVDGASTSDVEILVIDEDSNAFGGRTTTDSNGNWTVEAPDSTLHVVAQYKDADGNVFNTESYPYVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC7</accession>
    <name>V6DWC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C483_00770</name>
        <name evidence="3" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078031.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67315at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="2">
        <location>
            <begin position="125"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="228" mass="25561" checksum="DB9084B7419B09F1" modified="2014-02-19" version="1">MKTDSNGSLADGIQISIDLPLQDDRLLSGDATAEILLFLTRHHDESFSMTDLADAISYTRPTITKTVDTLSRNDLVVEEHDGTRRLVQINRDRLTIPDDPFLGIPQSEFHVPVQDATNQLRTTLDGVLAVVLYGSVARGEADRRSDIDLWVLVRDDRPSNQRQANHIRQSLEEDTFGGDRYAFDIDVEALQGVPTYAEELQEILRDGIAVYHTDEFDTVRSMVLHGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC8</accession>
    <name>V6DWC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02824</name>
        <name evidence="3" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077649.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49385at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="59"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="326" mass="33750" checksum="AB214FD004F62022" modified="2014-02-19" version="1">MTIQRREFVAALSAAGIVSTAGCSSTSGGDGNEGDGTAGNGTSDGGSAGGAAGVAGETLTLTTTTSTYDTGLLDAIHTDFEERYGVEVDAVAQGTGAALETARNGDSDVVMVHARGLEDEFLRNGHGVNRRDLMFNDFVIVGPESDPAGIRGMGSATEALTSIAEAGAAFVSRGDNSGTHTKELNLWEAAGTDPGGDWYQETGSGMGEALNIATQQGAYTLSDRGTFISQRSEIDLTILVQGPIEDGPEILANPYGVMAVNPGVHEDANYDLAMAYIGWITSPGVQASISEYQVNGEQLFFPEAVAEDPNFGQYVPEGWSRDSAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWC9</accession>
    <name>V6DWC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4746" checksum="68F85BAF56BD55BF" modified="2014-02-19" version="1">MHFVITRFSRLRRRIGIHKYLSEIIYVATSSRRSSHAGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD0</accession>
    <name>V6DWD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C496_23553</name>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078048.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="39921at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="301" mass="33836" checksum="BDA61D5E6372121B" modified="2014-02-19" version="1">MVLVSLLEFAHANRPIYFKPETDLEVFDDDEEEWDPLYKSPHSLSKLIEALKSNRVDAGNVRFEDSVAQEYLHHLKETGIDDQLHHEDLMNRERLVAFAEAGYTRVDDFLGTADPIDISKDTGVDRDIVSSIATNHLDGFSSGGSFGDTGPLQQLNPKDSFTGWDLVEASSNRIRWVSNGRFNLTISPAPDGSTTIACNAPEAERNAWYRKGRSIEAGPDDSLTPEEALEQSHEWLEAHQLEYEDDLAELPRIGAATKDYLALEYEITSREELRTFTADQPDEFDDIFGSPGSDLREALER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD1</accession>
    <name>V6DWD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage major capsid protein, HK97 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11060</name>
        <name evidence="1" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077241.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="133808at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024455">
        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="277" mass="29675" checksum="2AED0F6AF3B0D237" modified="2014-02-19" version="1">MSTILSNDVISQEAVRAEVESYAQSNRVFRQAFHPVDSTGIDSNTIEIPVLDETRAAGVVDEGTAYPSAGDATRKVTVEHDKYGVEVELTYESVEDALLDVVNLHTKERAQDLADALNEAAFAEISETDGGGNLVNLQGSVIGDGAGALAYEDVVDAMTALEAESYNPDLLIVSAQSKGNLMKSEAFTRASELGDDVVRDGAFGQVAGVDAIVDDSGLTSAGEAMMFDSARYGIESEREAMTSQKYEKESENKIVFQVRNRLGWKAIHPEAGVKIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD2</accession>
    <name>V6DWD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OE_6041R</name>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078035.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119938at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="12407" checksum="78BB9BB21CFC4C55" modified="2014-02-19" version="1">MSHEPPTPPANLPTEIVNTLNESDPEHLRDVATYAESLADHKEREARLEESADQEDVKERPDDLPDDVPSKATITIKEINDNRYYYWQWREGDQVKSKYKSPVDPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD3</accession>
    <name>V6DWD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_02719</name>
        <name evidence="1" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077655.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123117at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7729" checksum="1BB32AAB39E2B48F" modified="2014-02-19" version="1">MSDYTTISLRKEFVADVEEYIEEEPFGSVKEFVKHVVVQEMESDDEISEAEARRIGQRLRDLGYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD4</accession>
    <name>V6DWD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS240-type transposase (ISH102)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halar_2993</name>
        <name evidence="2" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="80"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="24423" checksum="B2D838EB45483665" modified="2014-02-19" version="1">MPENDRLSGCLDEINLEFVEREATPRLLMKLSIQLHLSGLSLSNTVSFLEIFGVDRVRSTVHNWVHKADLQPETGRKPNHVAVDETVIQLDNEQYWLYAAVDPDSNDLLHTRLEPTRNNAIADRFFAELREKHDVDDAIFLVDGAAPLQRACRKHGLDFRYERHGNRNSVERVFREVKRRTTSFSNCFSNAEAETANEWLRSFAFAWNQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD5</accession>
    <name>V6DWD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4819" checksum="FDF3DB21CD0CC10A" modified="2014-02-19" version="1">MLGLPGWFDAYFAVGDDLLMNELLPDGWPLLVAVYRLGNGVHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD6</accession>
    <name>V6DWD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11045</name>
        <name evidence="1" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077244.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="141708at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="12779" checksum="95C9C6845EDCAE2B" modified="2014-02-19" version="1">MLGRDFRVINYEFEANCGGENPYADGDWVEADISPQVAPATIDFGHEPERRSGQGNGVQVEQDAVIYLQQGSVDIQPGTGDEERATEFVDIEVGSEYRAVAVEEQLHLTAVHVEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD7</accession>
    <name>V6DWD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C444_16898</name>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12258" checksum="3CD001F62D6380EF" modified="2014-02-19" version="1">MPGEPYRIQENTGNPVHPSIEAVLTLALDRAADPRPSDHQDSHFDRYVQDAVEHAGEAAVKQAIRLSLTEGLTHRMAGRKAFGDDNYVYGINVGVAAIAYLRELNSNSLSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD8</accession>
    <name>V6DWD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_09214</name>
        <name evidence="1" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077657.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125915at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8026" checksum="A0154E06943E74CE" modified="2014-02-19" version="1">MIETETASAAAAALPPELQSPRAKLVYLYLTTNGDATVSEMGDSLGMKKLSLYSILKTLRNEGLVDCDGDCYVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWD9</accession>
    <name>V6DWD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9797" checksum="70646AFE261F87E5" modified="2014-02-19" version="1">MIIRSLLIAQLLHPLFIGLARLSRGSLVWARTARVAGLFRLLLVLGRCPFKQNTNFSNSQLIERCVTDELVAVIVDLLDPECLLPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE0</accession>
    <name>V6DWE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7289" checksum="58B1D320599C7902" modified="2014-02-19" version="1">MASEFGLDVREDGYLVDEEGDPVIPSGSDEPMTLEEFSGTGVGSRVFIKDDFNSVSEYVEEHRSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE1</accession>
    <name>V6DWE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_11035</name>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077246.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99372at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="399" mass="42472" checksum="57965D17FD0C05C8" modified="2014-02-19" version="1">MTNQATQADTGFRNHRVEFVREDEPGVTPADPKFELFSDTLETALVWSADANVEAQRGLGDYEIQDHFTGAEDHSVSVDYHLQRFFVDDSGSPLDPAGDALVRDDEGGIRSTHTVVDRAEYDGARTFVVARGAYPDLSDLSGDPSTALPMVASLEYEAKRVRMFRVEQPTGETLTVRSTSASDTSQTLTIEGDGSVPSEDVMLDGTTAVTTTETFDSIDAFELDSESAGDVVVEDGSGNELVRLRGTDSYDGAIGDLGVPALGAGSHASAIGGSYEHFLDDYISQGGSQMAAEVRSASFSVDNGYEKSAVMGTAEQAIHVGAQELEFTASVAGNFAHHENLTDHLEGNEFDLVWEMDGGTVTFTSAVLTGLGDVGPEAGEVISTMDNTFQPKSVDFTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE2</accession>
    <name>V6DWE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_08002</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="274" mass="29459" checksum="D4799379462F0F3C" modified="2014-02-19" version="1">MLLPSLNNGVTLLDVEGSRGVPIIQSLVLDHLLLHDGPAFWVDANGHATTTTLAQIAPSQRLLDRIQVARGFTAYQHYGAVCDLTAAVNQSIQASTANNHVQDGQPTDGDGESPYTPSLIVAPAVDAQYRADDTLGDRHANTLQARTLTRLATYADGYDIPVLVTRRTIDEFTEPVVAVADHHLECEQTRMGPRIRGEEFETLVYPVDDGAYYQTTFAYWRQLLTARATQVGVEPTTPASATSEAVGTGVTTKGETLAATTDPLLDAWTAAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE4</accession>
    <name>V6DWE4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="zinc_ribbon_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="191" mass="20112" checksum="7E2F1C2275970C1D" modified="2014-02-19" version="1">MSYCTECGTEVQAEASFCSNCGTDVSDLDTSQSSDAVEGDTDSSSWTTTDNSTTEDTSPTSNTGGRFSDVDFKRLAISVGIGFVVALMVAFGFAELGGAGFWALVTVLGVSSYLYKQTTNRKRTIGIGLYIIAAWFILAPIFFYIGVAGQSPNDFAAVGAVIGMVIYGFIGLLLAIVTGGLGYYINKRVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE5</accession>
    <name>V6DWE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_10216</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13800" checksum="74D6F7C682344DB4" modified="2014-02-19" version="1">MAERAVRYALEAHPDTEITVLHVVGEPSPMMGKAMSLALEDDIEQAAEEHVSAVLECAHDIADQFDTEITTDVAWGTPAKVTINRAEVFDTVIISSHRGTLADRLFVENVAQKVFRRSPVPVTVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE7</accession>
    <name>V6DWE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4810" checksum="F7F9545AF09E03A6" modified="2014-02-19" version="1">MTRPSPNPRSAPRCDRTIARRLGGRRNSRNRPSYRFPNVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE8</accession>
    <name>V6DWE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TRAP-type transport system periplasmic protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_14449</name>
        <name evidence="1" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077254.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="56367at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="327" mass="34031" checksum="78A947EBD0C6A665" modified="2014-02-19" version="1">MSDNPISDRIDRRTLLRGAAAAGIVGVAGCSGNGGDGDDGSSDVIRWHAGGTGGTYFPLSGEFEGIIEDATDYSVEVSSTGASVENVGSLGNGDADFALIQNDVAYFARNGEGLDAFDGSPVENLRGVATLYPETIHVLTNPDSDIGSLSDLEGMRVNTGDLGSGTQVNALQILESAAGLTTDDFDEQNTDFTQAANQLRDGDVDAAFVVGGWPVGAVEELATSTDVGILNLSDEERQAARDDASWFADDTIPGGTYGGIDEDINTVSVQAMIATRAEYSADIVEGVTAAIFDNLGELSIKTDFITVDSAQDGMSIELHEGAARYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWE9</accession>
    <name>V6DWE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helicase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C444_18322</name>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5145" checksum="4D9680C144ABF6DC" modified="2014-02-19" version="1">MTRPGHDQEPVVCAWGGDGVFTRIVVDGTENGPTDPLPTWCDQFLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF3</accession>
    <name>V6DWF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02614</name>
        <name evidence="2" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077663.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105703at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="11913" checksum="D3B6ED8B9BB7046E" modified="2014-02-19" version="1">MILVRGSGGGTDLTGTVFERGEEPPAYKGAPNEDAPYVWVCDAFYEVESGGSPLVVDGEEIRVAFEEPMPRGFDTRDQAVEAARDHVRTQFARIGVDPADVEVEVSAADPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF4</accession>
    <name>V6DWF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_02287</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078073.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102573at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14220" checksum="284EDA451883EC9D" modified="2014-02-19" version="1">MNARHIDHVNLRIPEDGVDDAREFYGDALGFGIEDALYAADDKPFFDVRLSATAVIHLWPTAEFEPPTPTNYDHVAVVVEESVDETATELADAGVEVEKTLDSPLGATGEAGAVYVRDPFGYRVELKARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF5</accession>
    <name>V6DWF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_12242</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="210"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="325" mass="36848" checksum="3C93444638D93D41" modified="2014-02-19" version="1">MNDKYRAEELLERVENGERSRELVEELNNLRDTENDDARDLIAIGLYTILAEEPHLFVRNPDDLFDDLHSTDEVTPTSARITFSWVAENPPDKLTEYIDPELLELLNHRDDLIRGSACRILAHFAGTDVNTVEGTAVGLRHLLKDENTVVQGHACLALGHLEDETALQQIKQLQLSDSQYTRAVAEWATEKIQTSGKRESIRWKHKDLFECEPVEFEQVVAALWSEMGYSTKVTQRVKDGGYDVDARNGDERILIQAKRHQNRVGVKAVRETAGLLEIEDADRVVVVTSSSFTNTVEKTGRIELLDGKQLCDLLTAHNIPRDEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF6</accession>
    <name>V6DWF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TrkA-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14434</name>
        <name evidence="2" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077256.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19570at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="488" mass="52087" checksum="12182CF3A8258968" modified="2014-02-19" version="1">MSSGASGSARTRYAILGCGSVGHAVAEELTERGKDVLILDRDESRVEALRDQDLNARVQDIADADVVDEIGDRDIVLILASDVEANKAAVSAVRETGGDHYVVVRASDPVSEDELRERGADVVINPSTVIADSALQSLETGELEYMARQLAEIIEEGGDRMAILTHDNPEPDSIASATALQAIAEAFGVDADIVYSGDVGHQENRAFVNLLGIDLLARADAPDLSEYGTVAAVDLAKSADDGFDFDAEIDIYLDHLEAEVPFDARFVDVRTNVSSTSTILTKYLQEFDQSPSEAVATALLYGIRAETLDFKRDTTPADLTAAAYLHPFANHDTLEQVESPSMSPETLDVLAEAIQNREVQGSHLFSTAGFIRDREALAQAAQHLLNLEGITTTAVLGIADDNIYLAARSKDIRLNIGNVLDEAFSEMGDAAGHSTQGSLEIPLGIFTGIEASGENRDTLLHLTEEAVRRKLFDALGVEGGSGDGSNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF7</accession>
    <name>V6DWF7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="19286" checksum="7BF26B1E4E97C2C2" modified="2014-02-19" version="1">MDLGVKIYLMYYYLLNLFSVLLEFYHQLVDISRFPAASRSPVLNDRCVLCTDRLRGKTISRCGFQQSRPNLYPSPADSSAHGRIPPRRARRDRLPAGGDRRRRAHRPQPPVRSDRSHARGAVSDRVGLRRRRDRAGPRRTSRRRRRQRRRRRHGRVPQRRPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF8</accession>
    <name>V6DWF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="18775" checksum="CB25958C9E51FB26" modified="2014-02-19" version="1">MDESTKEKWEEHLEQSSYGSMSELVRGSVRKEIQSDGDSSGSTSGQSLEVDRLKEQQQDTIQKIENLQEVVEEAQKEREKTEYPEDIVAAAHDIAGEMDTVSRDEPHPIADERYRELSKLSAEHFGDKNERDKIEAALNYLDENVSWIVKRPVLPSEYYRVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWF9</accession>
    <name>V6DWF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="131" mass="14579" checksum="7FDE7FDF63A8B099" modified="2014-02-19" version="1">MLKAVIEVNDRQPERLLNAKLDTADERVAVFGLAFNPATTTSGIPERFPPPRDSTRYVDIVPTTPPLQRTCASSSPRSSAPIVSIVYVQRTIETLTVTCPSERMIRTSASSPRDESRWLTAHRSISRTVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG0</accession>
    <name>V6DWG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C477_04164</name>
        <name evidence="2" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="457" mass="50181" checksum="F366945CEB740814" modified="2014-02-19" version="1">MRRYGIILLLIIVGVAAGTTATTGQQVQDRGPENCIDAFTAQQWESAQLTGEIRLAEDDTVQITYDGHGELTTFEVDPPAAATVVNTTGFSKTADGAYTFGGRQATPTLTYRLQTGLSTNESYASGESWLHTPLPSYTQTRVHHTTPEGGHVGTQFAYLGNYSAVTLQDGCHEVTGIIADESRSAVDSEQIERQLRYAMTEYDVGHRYSKTTVFVTPGKVDPTSSGEAHKSDAWASSRHGPSNTTHIVLHEYLHTRHSFGDASLGEMSWFNEGTTEYMSLRLMLGAGTLSPREYNNRLENAAGGRAVLSNRSTWTNHRVPYQRGTMFNAHLDYRIRNATDGESTLKDVVAVANAKQGSQFLPSERAVFDIVANVSNTDTAAWANGTVDSSQPFKVLPVQQKTTPEWEHRLSIARENLSEQPLLGVFFGLLLGILMMIISEEYGNDSEDDRPEKSENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG1</accession>
    <name>V6DWG1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HGPRTase-like protein</fullName>
            <ecNumber evidence="1">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_03324</name>
        <name evidence="3" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May catalyze a purine salvage reaction, the substrate is unknown.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077261.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88302at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01467">
        <property type="entry name" value="Hypx_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026597">
        <property type="entry name" value="HGPRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="2">
        <location>
            <begin position="41"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="189" mass="20839" checksum="D0EC7BBFB22D64D4" modified="2014-02-19" version="1">MDQLRQSLLDAPIIEKGEYQYFVHPISDGVPMLEPELLREIVIRIIRKAELENVDKIVTPAAMGIHISTALSLMTDIPLVVIRKRQYGLEGEVPLFQETGYSESEMYINDVEEGDRVLVLDDVLSTGGTMKAILDALTDEVGAEVVDVVAVIKKAGPNELDDTDYNVKTLINVTVEDGEVVIVDAQGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG2</accession>
    <name>V6DWG2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferases group 1 family protein</fullName>
            <ecNumber evidence="3">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Gobs_2208</name>
        <name evidence="3" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.250" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="224"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="397" mass="43228" checksum="9E30E26830B62724" modified="2014-02-19" version="1">MRVIALTDYLSNVGGAELSAREIVTGLAQRDDTKVTLVGGDLSDAEKLSFPGVDVSRVRIPDYVENLPDLVADSIAARRLAQAAEEHIEDADVVHAHHRRSTMAIRQLDTETPKVATIRDFWPICPISIYSVDGRQCRGCDDDLGNCVRHQGWDSPLSPVVKRYLLLKRHYNSGIIGTIDCNVFIADHIRETVRRSSQVASRTDVVYNPIDVDFSGPAASSEIPRFVTASSLLPQKGIGTAVRAMGLLDIDAELVVFGDGEERDQLKQLAKDIAPKKVEFRGRVEPEEVYRTIAGATATVFPSTWEEPFGRVTVESMALGTPIVGSAVGGIEEVIDDGETGLLFPPGDETALSEQLRRLCANPEFTASLGEAASTVSEEFSPQAVANKYYAIFEELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWG3</accession>
    <name>V6DWG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4556" checksum="5D6019925EBF828A" modified="2014-02-19" version="1">MRGGIRRCLPSLRDYRTITNQPAVRNSALYRRSVLVRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6E010</accession>
    <name>V6E010_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03586</name>
        <name evidence="2" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078307.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97752at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="14475" checksum="D867820C5AA3268B" modified="2014-02-19" version="1">MTDPTAHHVGVTVADLDRAVDFYTETFDLDVVAEFSVGGDAFAEAVAVEGASAEFAHLDAGDAVVELVAYEPAGEGSADPELNRPGATHLGLSVDDVEAFYEDLANDVETLSPPRTTSSGTTICFVSDPEGNLIEVLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E013</accession>
    <name>V6E013_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9152" checksum="360E2D30A37C488A" modified="2014-02-19" version="1">MLTSRVFLLAAARRYAPRAAGGEAAGDCPFDSRPTAPHHNLTPPQPRRPVSALLRPVDSLARCSSRSPLATARRHAPPHLFVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E015</accession>
    <name>V6E015_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15949</name>
        <name evidence="1" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="10258" checksum="625DB5B394B7E530" modified="2014-02-19" version="1">MKRVVEAAADLENADFGRSQHEAFERTFRALSDIDELDDEEGVRAIADWVVDRINEKESVPGSRDVRRQGAKYCRKNGYEVRDDEWLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6E018</accession>
    <name>V6E018_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_13837</name>
        <name evidence="3" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078310.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103559at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="290" mass="30772" checksum="B634C3E7E0402B5A" modified="2014-02-19" version="1">MFSGELLGPLAGAVLLGAVHGIEPGHGWPVAASYALDQTNKWVYGFAASLIIGVGHLVSSIAMVGAFFYAKGYFDLTQVNEPITVLGDVRIGGPVSLVAGFLLIGLGVREYVHGHSHGASNDAHDHHDHDSVDHHDRGSDDHHNHGSGGHHGHSHGTHGESDDHDDGGLGSRLRGFLPFVGGGGHSHSHDDFEEGTDRGLLGIAWFAFVLGFAHEEEFEIIALCAGSNYCLELMSAYALTVIAGIVGLTMLLIAGYHRSRERVERYTPYLPAFSAAVLVVMGIGFIVGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E019</accession>
    <name>V6E019_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4735" checksum="45B233C3FE9C5450" modified="2014-02-19" version="1">MRMTWTWTYVTIRAPSDNNCWFRPLKKEHYEGSERSVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6E030</accession>
    <name>V6E030_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C454_12533</name>
        <name evidence="1" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078316.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="14652" checksum="FB65B4F3DACDE888" modified="2014-02-19" version="1">MRRRQALLGTTAVLSGLAGCAGPFASDGSLGKVTVELTNTGDQARTFHLALETESGMLDWQSHRTNAGVNERVTITPDEDVSPVALHGAVENFAESADILGVGDLDEDYCLRFKFWYEHPTDERPQLAQVADTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6E033</accession>
    <name>V6E033_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08320</name>
        <name evidence="1" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078320.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92104at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="183" mass="20520" checksum="D91BBBD3E1C6BDDB" modified="2014-02-19" version="1">MRVRDWDDILADVASDSTDPDGWRAVAGSRRGGLGEDLYFGHPSVGLYHLKTYAKNPRDLRGVGTRVARKVDDELDPLLPDAESDGRFAVRSAPEDEDHAEEMATRLTETLRVHAEAPTDPDHLFEDVMEAVESPAFGPMEYEFDGRPDELDELSDTFEDAEELLTSELDDLIDEDDVDRGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6E035</accession>
    <name>V6E035_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS240-type transposase (ISH102)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_06237</name>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="80"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="24367" checksum="6443BC5E84EE6D65" modified="2014-02-19" version="1">MPENDRLSGCLDEINLEFVEREATPRLLMKLSIQLHLSGLSLSNTVSFLEVFGVNRVRSTVHNWVHKADLQPETGRSPNHVAVDETVIQLDNEQYWLYAAVDPDSNDLLHTRLEPTRNNAIADRFFAELREKHDVDDAIFLVDGAAPLQRACRKHGLDFRYERHGNRNSVERVFREVKRRTTSFSNCFSNAEAETANEWLRSFAFAWNQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E039</accession>
    <name>V6E039_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8365" checksum="85F0A77A583F0732" modified="2014-02-19" version="1">MRRSEPAGDDHGVVLCVVLVDYSRDLGDLVRDDRHASDADAPGVEAVAEPGRVRVLGVADEELVPDGDDGGVHTDSSGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6E040</accession>
    <name>V6E040_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">tRNA (cytidine(56)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="6 10">2.1.1.206</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">tRNA ribose 2'-O-methyltransferase aTrm56</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C472_14002</name>
        <name evidence="12" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>cytidine(56) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(56) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42968"/>
            <dbReference type="Rhea" id="RHEA-COMP:10308"/>
            <dbReference type="Rhea" id="RHEA-COMP:10309"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.206"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the aTrm56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.206" evidence="6 10"/>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078324.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83050at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00077">
        <property type="entry name" value="tRNA_methyltr_aTrm56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002845">
        <property type="entry name" value="tRNA_mtfrase_aTrm56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42197">
        <property type="entry name" value="PTHR42197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01994">
        <property type="entry name" value="Trm56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016123">
        <property type="entry name" value="UCP016123"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 10" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="10">
        <location>
            <begin position="131"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK40963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="22793" checksum="A2E5D2A8BEFDE938" modified="2014-02-19" version="1">MNDAREVVVLRYGHRPGRDDRMTTHVGLTARALGADRVIFPDNAGQSAETVRDITDRFGGPFDVELRDDQKAIVREFDGVVVHLTMYGERVQDVEGEIREATGLADDGEVGSAATAGGSPPSPRDVLVVVGGEKVPWALYERADFNVGVTNQPHSEVAGLAVFLDRLFDGTELDREWADADRRVVPEATGKTVVDAEEAAGSDDSGSEDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6E043</accession>
    <name>V6E043_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysulfide reductase NrfD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_15434</name>
        <name evidence="8" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NrfD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078332.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14255at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005614">
        <property type="entry name" value="NrfD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03916">
        <property type="entry name" value="NrfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="430" mass="46012" checksum="E1D6B76BF95253F8" modified="2014-02-19" version="1">MSTPTGSDRRAATLADPGPRYYAMLAVAGLVVLAMVYSFVTVLTQGHGITGLHNWGTDGGVPWGLDIGAFSWWSAMGVGAIALSAIIRVFHMDEYRPYARIGELLTPLAFGVGFLHIVFDLGQPFRVLNTLIYLPLQSPIAWDVILLAGLGTISVVYLVASLRADVYELSERDALPAALGPVYDALLIGYEPSETETGKGLTWWLAALVLVFIPVVGGGVVPLLWGPLGVNINWFGAIQGPTFLAASMTTGAAAVLFVGCVLRYAYGLDDVFTDRTLRRFGAVTGAFAFTYLLGTFYEIQTGSFAADMADPNVTALIFEGPLAPLLVLAIVAIVVPTAYLTIQHAVDRFSLLGTALLTGVMLVGILHQETWLIVGGLMYPDLPYQVGEYTPSIYEWLNLMGTTALVALVMLVFAKTLPVVSDPAEVGSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6E046</accession>
    <name>V6E046_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_15424</name>
        <name evidence="5" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="3">
        <location>
            <begin position="88"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="4">
        <location>
            <begin position="342"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="475" mass="53098" checksum="37861E1A84F76F3A" modified="2014-02-19" version="1">MGVQTTMAQYHASMLVGAVDVVGSTRVRKGKYAEPQDYRLPFRDQAFHPEKITPNPDGPSLGGSMFHPIDSTAYSQSHVSQTNPDKYNLPYDPEEMAWIVQMANPIHSAAGTDTVIESMSKVDTTVVVDPWMSETADVAADYVLPAATADKLQGPTGGWNGYADIKHIRFPSMDPMWNSKPDAEIFIQMAKAVDAFDEYVLDINDELGLDGTEYAYSGASEAPDDPHEFLRDGLDRWAKTKGKSLEWFREGNVITNEWEVGEGNRYAYTWGMDNGYGEFNPYDAKHEFYSETLFRLGERVDELFADSKFDDPEAEFPYLKDYTAFPTWRQPTMYDSPEEYDLTLFQWKQIEHKQSRSANNKLLNEIAPRASIRLNPKDADRIGVETGDEAVLKTHNAQTGETYESEGIVMVQDGIKLGSVGLPHSHGNWKDPVTEELDEGIHANKILPSGPGYLGFDNGQAFTIRATVEPKGGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6E047</accession>
    <name>V6E047_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_16527</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078337.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111287at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="39"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14321" checksum="64DCE1FBEF69E247" modified="2014-02-19" version="1">MSNQPNTSTDADSESASGTLRRIEGDACCEGPFPATRRVGETTLDAELSSFKALANAKRLRIVHALREGELCACELETVLDAPQSTVASHLRKLRDAGIVNTRKEGKWTYYRIADTASLQLLDLAAALGEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6E051</accession>
    <name>V6E051_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_15449</name>
        <name evidence="6" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078335.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32313at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="5">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="344"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="104"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="372" mass="39622" checksum="88C6EDAA22AC7A74" modified="2014-02-19" version="1">MTTELRDELAQIDDPALTEAPQTDGDADIVSLGIIGDVEVDDGVAHVELALGAPYSPTESRLAERVREVVREAGYEPSLSIAIDDDTPAGLIEDAPNVIAVSSGKGGVGKSTVAVNLATAIAERGANVGLFDADVYGPNIPRMLGVHDHPGMAEDDETIIPVERHGLKLMSIGFLVGEDDPVIWRGAMVDKVLTQLYDDTRWGDLDYFVVDLPPGTGDAQLTMLQQMPVLGSVVVTTPQDVALDNARKGARMFDRHDAEVLGFVENMSTFVCPNCGDAHDVFDAGGGERIAEEFDRPLLAEIPLDPSIREACETGEPAVSNDDTEAARAFESLAEGVMDAVGALRRRSHSETARSTVDESRSAAERADAQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6E062</accession>
    <name>V6E062_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_07472</name>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078342.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129760at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7428" checksum="87A2778DD9AE9D51" modified="2014-02-19" version="1">MLLSASEPSSDADGAADDEVVAAAERLGEQLAAAKAESSEFAFTTMLMQCNEAIGDETGIDYGSVCGDDDGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6E064</accession>
    <name>V6E064_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_03497</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="23607" checksum="3BDBBD7AD8F7D813" modified="2014-02-19" version="1">MTQPVDENCALIINRRNKLPKRQHQQLLSSKKMRDRKYLLRVKIWCSMPSPLFSRASIADLDRRAFVGLLGGIVGLGLALQVFLVTNTTAWTIELERLITLVSVIVAIVVYVRTRPTARAWEIGVLAVWGAIVQWLVSLVWFIVGPALAGEVSVSAILLSGAAELCLAEVGRYLGTVAVFAGFYTVAASHREQPIISVLTLLSVPVVMIVVYAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6E067</accession>
    <name>V6E067_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01554</name>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078348.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124641at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8675" checksum="A859A84909DEF48D" modified="2014-02-19" version="1">MSVRLYALDGCPFCEKAADALDDAGVDYETEWVEALHSERNGVKRVSGQRGVPVLVDDERGVTMAESANIVEYVERTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6E068</accession>
    <name>V6E068_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosine deaminase-like metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01539</name>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8484" checksum="165C49B010486F6A" modified="2014-02-19" version="1">MFREMASAAKRFDVSAREVLRMATTAGAEIADLDCGVIAPGRRAALVVLDGDSDNLSGSVDPVRAVVRRATPLDVERVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNL1</accession>
    <name>V6DNL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SOUL heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hlac_1279</name>
        <name evidence="3" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_haem-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="PTHR11220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="24049" checksum="873800898349E2E9" modified="2014-02-19" version="1">MRSLTKMILVGGSVVLAGWVGWGFYSTKKAKSVPYEQLRTVNGTEIRRYPQTILAETTAPTQRIAFQRLFRYISGTNQSNESISMTAPVETQSGDSIPMTAPVRSEATETEAETVRMAFYLPSEYTPETAPEPTEPDVTLITEPEKTVAVDQFSWYAPEWRVTRRTQKLLSTLEREDIEPESDPYLLRYNDPWTPPFMRRNEVAVKIVEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNL2</accession>
    <name>V6DNL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fused rhodanese domain-containing protein/hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_12826</name>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075794.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25677at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="27"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="397" mass="42741" checksum="D8E05405D8375819" modified="2014-02-19" version="1">MNADDFPTPDAEVASVEPETLKDRIDAGNDVTLLDTRMSSDYEEWRIDGENVTSINVPYFEFLEDDIDDDVLDRIPDDREVTVLCAKGGASEYVAGTLVERGYEVDHLEDGMNGWASIYETVEVSGYDGAGTLLQYQRPSSGCLGYLLYDDGEAAIVDPLRAFTDRYLDDADELGVDLKYALDTHVHADHISGVRDLDTAGVEGVIPEAAVDRGVTYADDLTNAADGDTFEIGDATIETVHTPGHTTGMTSYLVDGSLLATGDGLFVESVARPDLEEGDEGAPDAARMLYESLQERVLTLPDDTLIGGAHFSDAAETAADGTYTATIGELVDEMDALTTDEDDFVDLILSDMPPRPANYEDIIATNLGQNVVDDEEAFTLELGPNNCAASQESLAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNL6</accession>
    <name>V6DNL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_01595</name>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075797.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92938at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="161" mass="17156" checksum="FAF738E8AD45418D" modified="2014-02-19" version="1">MATSENESKDTITAYQERLDALDATLASKMDRWSVPALRAAVGAVFIWFGALKVLGVSPAGDLVASTVYILPPEFFVPVLGVWEMVIGVCLLYPPLTRAGLLLLALQLPGTFLPMVLLPEVVYTTFPYGLTVEGQYIVKNLVIIAGALVLGSTVRDGSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNL9</accession>
    <name>V6DNL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH4-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C488_04262</name>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075788.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36015at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024442">
        <property type="entry name" value="Transposase_Zn_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12760">
        <property type="entry name" value="Zn_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="120"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="294" mass="34206" checksum="564FCDE97E527605" modified="2014-02-19" version="1">MIPLDAFGSESVAADLLQQVRWRDGVSCPRCRSDRTVRNGSYGHFQRYLCKDCDRTFNDKTGTIFAHSKIALRKWLFSIYAFLRFNTSIRQLQCEIEVTYKTIHRRVERFAEALDAPSLDLRGPVEIDEFYVSAGLKGRERDRWSRSRGLSRRGRGTYEQDKPPVFVLVDRGTEQRYIVPAKSADESTIRLLLADRQQEPLPVYTDGFCAYDPLEEDEKFDREYVVHGDGEYADDTVHVNTCESHASLARRWLSPHRGISKDRLTQYFRAFQLRRELYRKPGREALKHAVKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNM1</accession>
    <name>V6DNM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C471_10575</name>
        <name evidence="3" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075799.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97382at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="184" mass="20675" checksum="88054AA6A62EDC6F" modified="2014-02-19" version="1">MTPHLITKGAATSDDDGPSRDEVFTALSNRRRRNIIRYLKQHDGDDAKVRDIAEQLAAWENDLEIHEVTYKQRKRVYTALHQSHLPKLAEGEFIDYESDRGLVSLTEESKQLEVYLEVVEENEILWSEYYVGLATVCGLLAGAAWIGTVPFAGVSGYAYAMLFALLFGASGVVHRMITQQNRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNM5</accession>
    <name>V6DNM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5874" checksum="C0158968DDCC677C" modified="2014-02-19" version="1">MVSDDGNRDSRRFPPSLQALAVIAIVLLEAVLLYVGYGTVEDAVGAIVLDRLAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNM7</accession>
    <name>V6DNM7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_14917</name>
        <name evidence="3" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075801.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72467at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="13"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="266" mass="27857" checksum="9E6AD8124818AC67" modified="2014-02-19" version="1">MLESLFRIDVALFVLIGVLGGAHCIGMCGPLVTMYSKQMTPQPDGGTATVDDGRAGHLTTYEVRQHFLFNVGRATTYAVLGAAFGALGSVVFVTTDQLTPVADVLRGTVGLAVGGFIVATGVRYVIGGSGGDIRIPGVQRVTSWLAARVHRHVNSPSIVGLGAVHAFLPCPMLYPAYLFAFASGSPTTGGIALGALGVGTIPAVFLYGTVIQSIDVAHRRRVHRLLGVVFVVLGYVLFAHGLMALGIRIPHPMFPHYQPLGGAMGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNM9</accession>
    <name>V6DNM9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulf_transp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C465_12763</name>
        <name evidence="9" type="ORF">BN903_116</name>
        <name evidence="8" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="7">
        <location>
            <begin position="34"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK37917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="10849" checksum="7FB5975AB9EC94FE" modified="2014-02-19" version="1">MFGAAIVSGIAFALLPRIRDTAPLTGTPYERRLKPFDRNVLVGGAVFGVGWGLSGICPGAAYASLGVGNITILWALGGMFLGAYAQGYWRSRSQTRDAAPASAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNN1</accession>
    <name>V6DNN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NikR family transcription regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nikR3</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075805.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90041at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NikR_C" evidence="1">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="15437" checksum="7806C405BFED22B7" modified="2014-02-19" version="1">MTEQLREDLDSFAEEHGYSGRSEVIREACQGLLEEYQKSDYENRRVLATVTAGFEYDAPDIEHKMMDIRHEFESLIRSNSHNCLESNAGCVETFVIEATGDDVLRFIGTIRGTDESVSVEYTVIPVDELHAEPSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNN3</accession>
    <name>V6DNN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C442_15170</name>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075796.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100378at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032836">
        <property type="entry name" value="DsrE2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13686">
        <property type="entry name" value="DrsE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20399" checksum="D91CD8B1BF211093" modified="2014-02-19" version="1">MSTDTPDVPSDGGPSRAELAARVDELEAALADATTEDDAKKMSIIATKGTLDMAYPPLILASTAAAFGYEVTVFHTFWGLDILHEERSKNLKLSSVGNPNMPVPNAVGALPGMDRVTTKMMERRIADNDTASIEELLETSLDMGVEFQACQMTIDLMDYDEDDFYDGVTTGVGAATALQDMADADIQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNN5</accession>
    <name>V6DNN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NikR family transcription regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14997</name>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075809.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90041at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NikR_C" evidence="1">
        <location>
            <begin position="53"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="15020" checksum="9BA4462D463250A6" modified="2014-02-19" version="1">MRTSFNISDDLLAEFDETWQSEGLDSRSRGVREAMQEYIEDHARLEDIEGDVVVIISFDYEHEAVIEDIHDVQHRFQDVITTTNHIHEGEWCLETLFCSGAASRVRDLTYRLRNFDAVSQVKLMLLAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNN7</accession>
    <name>V6DNN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4279" checksum="C958CB95248777DB" modified="2014-02-19" version="1">MTIALAELTDPDIEREVRQLKAEQTVSEDGHDQSVTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNN9</accession>
    <name>V6DNN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt-precorrin-2 C(20)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.151</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15022</name>
        <name evidence="3" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.151" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075814.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83180at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043781">
        <property type="term" value="F:cobalt-factor II C20-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030788">
        <property type="term" value="F:precorrin-2 C20-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11645">
        <property type="entry name" value="Precorrin_2_C20_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012382">
        <property type="entry name" value="CobI/CbiL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036427">
        <property type="entry name" value="Precrrn-2_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR036427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="221" mass="23928" checksum="4BFDED0644A45BF4" modified="2014-02-19" version="1">MTLYGIGLGPGVTDLLTVRGKRRLKSVDVVYSPGRLSRRVAAEYVPDSKLGDLEFPMTTDPNELQAAWQTAAAEVAPNAQDADAAFVTLGDPCIYSTFGHLWRTLSDQHPDVDVEVVPGVSSMTAFASVLGVDIDAGAELTLREATGGTAPIGPDRLILFKVTDAPTTHKKLVEAGYDVTFGRRLFMDTEETLVSNDPTDVTDRDYYTLAYAEKRNATDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNQ1</accession>
    <name>V6DNQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_01715</name>
        <name evidence="2" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="SSF57667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5574" checksum="35CC9ACB5032A93B" modified="2014-02-19" version="1">MSYACTNCDAQFQSAAGVTQHVALHHDRCAVCDEEFEGTDSLREHVHESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNQ2</accession>
    <name>V6DNQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type transport system permease protein (Putative substrate cobalt/nickel/biotin)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cbiQ</name>
        <name evidence="6" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075807.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51220at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK37867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="270" mass="29598" checksum="7634C21AF1E90A96" modified="2014-02-19" version="1">MTTLSNHVPDPRLITAFAERRDGPLHQVNPWTKVGIIGALVLAVTVFDRLALLAGLYGTVLIVYGLAKLPYRRLVGWYTLPMLFIVSVAGPLAFFEPGTPIGGALSTPLGNISVTWAGVILFLELSCRSLTVVTFALTASMTTKYTDVAYMLGRLLPRPIDQVALLTYRFTFVMLETLEDLVKAALSRGANFSEFWSNKRLYARILGMTMLSAIEQSERLVKSMEARGYDGDIVLYGDVSRPPIHELFVVAGSYVAVVGYALIAVYKVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNQ4</accession>
    <name>V6DNQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4158" checksum="44796012AC05F09C" modified="2014-02-19" version="1">MAGVDRRRARVAGGRVHRVDRSRGGTTGVCGAGYSVERGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DNQ9</accession>
    <name>V6DNQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_11501</name>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076133.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44952at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="110"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="275" mass="31218" checksum="A9728D4329F312AC" modified="2014-02-19" version="1">MSKISRFTSKAVTLAKNAVGGRGEAAAPEGGGGFADYAVVSLHCLRIYLEKSYRDALDLLSEMPQILAEIGLEKGDLPHHSTLVKAFDRLQIEVWRVLLRLSAQLHDTADHAAMDATFFDRETASKHYCRRTNYRVQTLKTTALVDTKTQAVLDVHCTTEKRHDTQIGWQLALRNAGEIASLAADKGYDWQRLREKLREEDVRPLIKHREFRPVDCAHNARIDGSLYGQRALSETVFSTIKRTLGHAVRARVWYREFREIVLMCAVYNIKRAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT1</accession>
    <name>V6DRT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_15916</name>
        <name evidence="2" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075833.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103666at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="13819" checksum="2794316AE25CD756" modified="2014-02-19" version="1">MSDTGSKRAESQSVRQILDALSEETTRTILSVLDEPTSVAELVEECDIAMSTAYRRLDTLNELDLVTEHVAIDTDKGRYRLFERNVNGFTISVDEAGRIRTRVERPTDSPDEEMTWRPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT2</accession>
    <name>V6DRT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4364" checksum="79EB9B6FAFBB7D6D" modified="2014-02-19" version="1">MSRTTCPSSDSAGRSLSIALSDLLKRQYPYQESFYTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT3</accession>
    <name>V6DRT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4402" checksum="C2179C4B80AEBA4B" modified="2014-02-19" version="1">MDRRLLKPGQRVLGRRARRSEVPGGSEERGVPNRSSEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT4</accession>
    <name>V6DRT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5240" checksum="C152CF7B59AA7B20" modified="2014-02-19" version="1">MSRNRSIISSSLTLGVGPGFDSSLIRTSIACNQLTIPSKAVHLISVPSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT5</accession>
    <name>V6DRT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome d ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C465_01729</name>
        <name evidence="7" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075834.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75259at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK37908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="333" mass="35985" checksum="048D5818D008E590" modified="2014-02-19" version="1">MTEPLLLVDAYLVDALPEIWFGVVMFALAMYVTLDGFDFGIGILYATRDDEHEKETFLTAFGPVWDANEVWVVAFGTMLLAAFPRVYSRVLADHYLLAIGFVLALLFRGLGPEMREQRDDERWKRYWDYSFIGGSFLAPLLFGTLAGRWVFDVPTLSLPALLTGVGLVAVSVVTGAAFLTAKTGPQLASDLRMYGIIATLVYLIGVVALLTTVVVTDAGGAAETVLSLPVGTIVFLSVVAGGGGSVLALRGEYRTWLVGALALPALLSLLVALLLYPTIYPPTGLTVREAVVSPLALNLVTILGFPALLLVLWYFKFLYGVFSGPIEGEGYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT7</accession>
    <name>V6DRT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4997" checksum="0AA4A474BAC9A8D9" modified="2014-02-19" version="1">MLRRHVRLHRLSIPSHRSRPGILASLTSIYPRFPDKVTYLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT8</accession>
    <name>V6DRT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8484" checksum="96BAF8DF816EF0C1" modified="2014-02-19" version="1">MSESGTRLPSLEWRPYPYLRFPERSYTKLRKVLGLVISNHRKGGEYNEAVYDLFDLTVDEGEVAKSLFKTNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRT9</accession>
    <name>V6DRT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C461_08694</name>
        <name evidence="2" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="156"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="286" mass="31628" checksum="5401D934EAC6CA43" modified="2014-02-19" version="1">MSSVTVKSAVLATDLSTASQTMIESETGLRCLSQIGVEQIHLVTVVPSSVHSGMPGINFEKRRKRALGRYQSQIEDAGFGAETHVVRGTPHRRINGIAGTVGADLILIGSRGESPLENRVIGSTARNLARTAVVPLLVDRIERGTDTPGTVRRHLFKRTLFATDFSENAERAFNTFEYLRHATEEVTLVHVRSPKDDTGDHAEVESRMQPLVERLGEWELDAKTDIRRGDPTKEILRAEREHEPSTILLGSRGRSRLRRLLIGDVSEDVVARASGNVFLVPQRRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRU1</accession>
    <name>V6DRU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4193" checksum="808008691574DC67" modified="2014-02-19" version="1">MREARGANGVSASKGGRRTDVSREQRASRTARTGATGGSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRU3</accession>
    <name>V6DRU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01596</name>
        <name evidence="2" type="ORF">BN903_180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076633.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40810at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="287" mass="32545" checksum="8BAECDEB2BF28966" modified="2014-02-19" version="1">MDDQRFLESEWDYCLVLDACRYDVFADVYDEYIDGTLEKRRSIGSSTPEWAYRNFTGGHDIAYFSGNPFINDLGIPLNELKWGASCDYEWTASDHISDIHDVWKTDWDDDLGTVPPEGLADAFHRNQDAVERAERTVLHYMQPHAPYLSRGKGQKLKQIQKGIKRQEEEEANGGGDDGGLLSSLSDSVRPKIESRLDDSEFAQKAGLWLELDPKDLVKDGTRVTALSMYEENLRIALESVAELVDELDGDVVVTADHGEAFGEEGVWEHHIETYIPALMEVPWLEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRU4</accession>
    <name>V6DRU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5232" checksum="324F5DBCE022C6CD" modified="2014-02-19" version="1">MSAAQDYTIYSIKEPVHNTSEIRPSPAATTCPFSFASPTLSPSKTDADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRU6</accession>
    <name>V6DRU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C442_15170</name>
        <name evidence="1" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075841.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100378at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032836">
        <property type="entry name" value="DsrE2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13686">
        <property type="entry name" value="DrsE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20397" checksum="2DF3760F0DAFEC16" modified="2014-02-19" version="1">MSTDTPDAPSDSAPSRAELAARVDELEAALADAAGEDDAKKMSIIATKGTLDMAYPPLILASTAAAFGYEVTVFHTFWGLEILHEERSKKLKLSSVGNPNMPVPNAVAALPGMDRVTTKMMERRIADNDTATIEELLETSLDMGVEFQACQMTIDLMDYDEDDFYDGVTTGVGAATALQDMADADIQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV0</accession>
    <name>V6DRV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4773" checksum="0A9464C74B8DF1BF" modified="2014-02-19" version="1">MSDEQNQDGIRVPADEEEAIDMAGAETEEEQNLAVAQARLIGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV2</accession>
    <name>V6DRV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C486_13782</name>
        <name evidence="1" type="ORF">BN903_213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076656.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105639at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="14819" checksum="4E98E173CE63ACDE" modified="2014-02-19" version="1">MNHVASYMTYRLPDKRVPETEPWKDREFLQWAYHERGLSARTIAYELGVSKSHVTVHMERLGVLRPWRHEDTLRRLYAEKGLSAGEIAARDEFDCTATTVQKYLSRYGLTNEDPDDVTYGRLDELAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV3</accession>
    <name>V6DRV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate hydrolase</fullName>
            <ecNumber evidence="2">4.3.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02959</name>
        <name evidence="2" type="ORF">BN903_190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.3" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076644.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72644at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="49"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="247" mass="26507" checksum="343484BE765B4981" modified="2014-02-19" version="1">MYRARFRDPAGSIRDGEYDPATDTVAFGGDEYALEDPDIDVLAPTDPSKIVCIGRNYADHAEELGNDVPDRPLLFLKPPNAVASHGDTVTVPAGKERIDWEAEFAVVIGEQCKAVDAADAMDVVAGFTCMNDVSNREDQNKEQNWVRGKAFDGAAPLGPVLATPDEVPADASVELRVNGETKQSSDREHMIFDVPTLIEEITTYLTLEPGDVIATGTPEGVGALADGDTVEVEIEGVGTLEHDVRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV6</accession>
    <name>V6DRV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5969" checksum="BEA4054F22991BEC" modified="2014-02-19" version="1">MRSRRVERRTEADGRIHRGRLSYLETPLKLSARTRERVKRPVVQVGFMNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV7</accession>
    <name>V6DRV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Site-specific recombinase xerd</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C476_00637</name>
        <name evidence="6" type="ORF">BN903_195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076647.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20145at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="32"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="175"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="366" mass="42800" checksum="0D5E8673170E82E4" modified="2014-02-19" version="1">MSRDKPEKVEGIVLIPRPSRDYLNERQRVAYKSHRQKLLKWLARQGKNPDALEGYAHHTAKNYASIIDRFLREMWSRDRYTLDVGHDDAEDYLRSLLLADDEYSKTHLHNTKLALLAYFRFQGDEWEPDITISSSSGVSQPRDFLSDDERIALREAALEYGTVPAYAALEPKERTKWKRFLARRYGKPTSEVSRDDWDRANGFKYPSIIHTALDAGLRPIEVGRAQTYWVDVENAVLRIPEEESSKNEDNWTVSLRRETTEYLARWLEQREMYEKYDDTEQLWLTRHSNPYSGSSLRYVLEAVCDLADIERDISWYAIRHSTGTFLAREEGLAAAQSQLRHRSIETTAKYDQAPVEDRRDALDRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV8</accession>
    <name>V6DRV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_04123</name>
        <name evidence="1" type="ORF">BN903_218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6739" checksum="6CAA5C5A66643481" modified="2014-02-19" version="1">MDFVEPSPSLETGEDLLDVVPMLRARFAAERVVPDYTAAFVHQHGLDVVVEDGEQRLVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRV9</accession>
    <name>V6DRV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_04183</name>
        <name evidence="1" type="ORF">BN903_222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4126" checksum="49DFC920E189C9F7" modified="2014-02-19" version="1">MDSRFLTPDDLAAAMDAVGLDPRIVDRGFGYTVAGVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRW0</accession>
    <name>V6DRW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64431at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="9716" checksum="BA05B566C8B50E07" modified="2014-02-19" version="1">MKRVWLNQSDVNDEAGTLIDEAQSPQQRVFFRLGAQAGLRREETASVTTNNRTSQVHRYAQKYRRGWDPWYHFVPMGWSYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRW2</accession>
    <name>V6DRW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_15500</name>
        <name evidence="1" type="ORF">BN903_226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="9453" checksum="16A9BD83B3E9EBCB" modified="2014-02-19" version="1">MINNDIRYHMTIRESNRQLRLRRTGRMPSDARVRHFDELSDDEKQVVAELAGRPRTAPETSTLEDGDVVKFTDYYLVRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRW5</accession>
    <name>V6DRW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="9318" checksum="EB5F2F8B2C2359A7" modified="2014-02-19" version="1">MIPQREPYRHVRWGDAFRHLTDRTDQPVDRDDLRTHLEHRWFALDDLEADIDEAVYDLFDLTDDEREIVENYLSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRW6</accession>
    <name>V6DRW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4255" checksum="CF3D564126CF2D93" modified="2014-02-19" version="1">MDIVSLLTCEYGGRTYKPRSEFPFGGTDLSGTHHPRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRW9</accession>
    <name>V6DRW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">L593_14470</name>
        <name evidence="7" type="ORF">BN903_148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075855.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="65191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK37948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="273" mass="28925" checksum="EA8A78FCD7B94CFF" modified="2014-02-19" version="1">MSWAIIARKEFRDVWGSRRTRWLLGAVALLFVAGGYVTPIMAGDEPTSADYASFMLGSAALLVPLVGLLLGHRTIVDERSSGRLTLLLSLPYDRLDVVIGKYLTRVAALGAAVAVGILAGAALVNYPFGSFEIGTVGAYLLGTLLYGAAFVGIGLAISTATSSSAVASSAAFGVFFLFVVVWSQLQGVFRAGLNYLGLADGTMPDWALFVYGVEPGMAYRRLVDGFFAGVEQGTYLGPDAPWYLGEWVAAALLAVWALGPATLGYLRFRSTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRX0</accession>
    <name>V6DRX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">sn-glycerol-3-phosphate dehydrogenase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glpC</name>
        <name evidence="7" type="ORF">BN903_236</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCG" evidence="6">
        <location>
            <begin position="49"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="CCG" evidence="6">
        <location>
            <begin position="182"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="285" mass="32002" checksum="34854439C217DFBA" modified="2014-02-19" version="1">MNFGPARWALEKVMGIPKERDFPEFATETFREWWKARGGANVENPDKRVAYFHGCYSNYNTPEVGKAMVRVYEHFGYEVMVPPQKCSGTPMFANGMLDDARRHAETNVENLVEAIGEGADVIASCTSCSMSLRQEYPELFDLHGIEDLAEHTFEAMEYLRIHEDLDGELDAAGGLDEERELAYHAPCHARNQGLARQAVETFRDVDGVTVEDVGDSCSGISGTYGWKEEKYEKSMEIGEEMFEHMEDAEGDVGMTECPTCAMQMEHGTGYEIEHPLQLLEDTLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRY3</accession>
    <name>V6DRY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TraB determinant protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04438</name>
        <name evidence="2" type="ORF">BN903_243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PTHR21530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="265" mass="27701" checksum="02418218F2A0B7AD" modified="2014-02-19" version="1">MVTMMMEEFRQFSPGGAEALIDERDAFIAHRLVALRDAGYDVVAVVGAGHRAGIEGYLRSPATLPPMADLVGEESGRGLPWKKAIGYAITVGFVGFFVLLALGGAGNAFLIRLFGAWFLINGVFAFAFAKIAGARWLSAGVGGAVAWMTSINPLLAPGWFTGYVELRSLTVNVADIGALNELLGDESRSMTDLLSAMLDVPLFRLIVVVAMTNVGSIVASFLFAAYVIPAMFGAEVGGVEDVGRLLVDGAVNGADLVRGAVGGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRY5</accession>
    <name>V6DRY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_0867</name>
        <name evidence="2" type="ORF">BN903_251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="13276" checksum="81A1B3BC05451A0E" modified="2014-02-19" version="1">MTVLMARARLPRCDDRFGSRLHRRSTRQSGRRRGVPTTRVRGRSARALRRRSGGTMTEPGDPRATGDEREETGQRGEDTDHETDREPDDGTDHLDDVEDGAGCTEIWERLSERREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRY6</accession>
    <name>V6DRY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-dependent pyridine nucleotide-disulfide oxidoreductase</fullName>
            <ecNumber evidence="7">1.18.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_04213</name>
        <name evidence="7" type="ORF">BN903_225</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076664.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="33756at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008860">
        <property type="term" value="F:ferredoxin-NAD+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="4"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="6">
        <location>
            <begin position="329"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="412" mass="45260" checksum="8021ECEC1BBABA4D" modified="2014-02-19" version="1">MSDSYVIIGDGIAGASAAETLREEAPDADITVLTDEGESLYNRILIKEYAKGKLPEAPISIHQEEWYDEHDVDLRLNTVVVDIDIDEDAVHTHEGETFEYDSLLLAIGGTPQQLPVENADADGIHHFWTFQDARRIKESVEDAEKAVIVGAGLLGIDFAAICGAQDVEAKYLMRGDNWWRYALSEEGAEIMHEAMRERGVEPVFGSGVDHFEVDDDGHVEAAVDPNGERYECDFAGVAIGLNFNTELVEDTPLEVDDGIVVDEFMRTNVDNVYAAGDITTFNDLILGERAKNGSWGSAKEQGTIAARNMVDYGSEEFEWVSSYSITHFDFPFLSFGHPTLGDDFVEATTADGEWRRVALKDGKVVGGVLIGDLSPQSAFKQLMREGRDVSDHADLLMEPGFAVDDLPASAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS50</accession>
    <name>V6DS50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cys/Met metabolism pyridoxal-phosphate-dependent protein</fullName>
            <ecNumber evidence="2">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00070</name>
        <name evidence="2" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="18762" checksum="B32D59E45B581F93" modified="2014-02-19" version="1">MTRRVDERLGFYQNSVGATPGPFDAFLVLRGTKTLPVRMDRHCENAMALAEWLEGHDAVERVYYPGLESHPDHELAAEQMDDFGGMLSFELDGTLEEASTVVSETEVFTLAESLGGVESLIEQPAAMTHAAIPREERLAAGLTDGLIRVSVGIEHVDDMKADLRAAFDAALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS51</accession>
    <name>V6DS51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04713</name>
        <name evidence="2" type="ORF">BN903_290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076720.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119495at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="140" mass="13958" checksum="66A9B8F6A2C75F92" modified="2014-02-19" version="1">MGLLVVATFVAVAEIGGKRSAPGRNESGGRYEAVVATLGEFVRTPVVWAVSFVGVTVLVGGSILLGVGSFGIPEALAGTLVNVAYLIVGLLLVGFVFLGAYFATRSRGLGNAHGVAAGTLATGAAFLVLVTVQLVVGVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS52</accession>
    <name>V6DS52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075918.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="15895" checksum="52C5DABFA68A539A" modified="2014-02-19" version="1">MGFYYHSEDLEAEAILRKCANRLDDAPTDINDIDVTKRDAVLAEDLIESEFTSDWVTANYTESGAIQLDTPYPELNEESREKEQQHLKDKRGQFFYVIGEISGEGTTVAISALAEIRGRAAEEKVEYFIGEYTLGHVDPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS54</accession>
    <name>V6DS54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4752" checksum="A10F247264654C9F" modified="2014-02-19" version="1">MSIRFLPIRFSSWLLVAAARRLPIEPLVEAGQAEAAASGATKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS55</accession>
    <name>V6DS55_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cation diffusion facilitator family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_04738</name>
        <name evidence="1" type="ORF">BN903_295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5420" checksum="76D3981AF785923C" modified="2014-02-19" version="1">MTLREAHDVETELVTSLRGLEDVGDVHVHLDPSGLGEWKDAPDAVDAPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS56</accession>
    <name>V6DS56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Hlac_1090</name>
        <name evidence="7" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076792.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="359" mass="39125" checksum="4AA0BF7B1C491DE9" modified="2014-02-19" version="1">MSNALSRAVERYGAFRDEWYALPVLVAVSLVVLAAMPFLRQLALFGFAPLGWLSLNMLIITLVWATTAQAWNIMSGYTGQFSFGHAAFFGLGAYTTIILTDTFAISPWIGMLLGSVFAGVYGLLIGALTFRYDLEGHYFALATLAFAELLRYVFTNVPQLGGASGFFRPLARDYASGPGLVAFQFTGDLPYYYLILGFLTIVTVVSLAINRSQLGYYLFAIREGEDAAAAIGVPTYRYKLLAVSVSAFFTAWPGAFWAMYFNTIRPSTVFDLLVNVEILLPAIVGGVGTVLGPIVGSFVIIPVSEFVRQSFSIPGLNNAVYGAILIAIVLYSPKGVISWPSRFIELLRARTDLFDDDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS57</accession>
    <name>V6DS57_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_06300</name>
        <name evidence="7" type="ORF">BN903_243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Archaeal flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the archaeal flagellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097589">
        <property type="term" value="C:archaeal-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35903">
        <property type="entry name" value="PTHR35903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01917">
        <property type="entry name" value="Arch_flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0974">Archaeal flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="33296" checksum="19185EA40519108F" modified="2014-02-19" version="1">MTTQDTDRGQVGIGTLIVFIAMVLVAGIAAGVLINTAGFLQTQAEATGEESTDLVSERVNVNSEVGVVGDSTAGTLDEIRLSITGAPGAGQIDLSETTIQAVGPGGQENLVFVDSTSGGSQVTQLSVPAIAASDTSVSISINYDNIDGLDAADTDQDLVLEYHAGGVSGAADDTTTVTGSSLDGQSFTFDSAGSGDSEINTGGSLSAGDEFVVDLQDTSDSSVLDTQVTQTVDSGSAAESTTTSGGNSVADLGANEFAVGEDGAFESSPVLNDQDDYTILINPAAGAFDDGTAFNQGQEATLDIVSPVGATTQVELRAPDLFSNNGEAVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS58</accession>
    <name>V6DS58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5921" checksum="147D264E6C90F2BC" modified="2014-02-19" version="1">MGAGVSPSLDRRRSKPLYPRFGNNLMRDHAGLWPSQAWRLTPEARARDDTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS59</accession>
    <name>V6DS59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4123" checksum="5AF1E50305A64A00" modified="2014-02-19" version="1">MITQPFAAADPAGRIDGPHTGNRLIPGPDPDTTIPREEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS60</accession>
    <name>V6DS60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C469_13690</name>
        <name evidence="3" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076790.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="23923at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="82"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="447" mass="46437" checksum="B7546DE4F94A53B5" modified="2014-02-19" version="1">MGDNPRDRVSRRSFVKYSGAAGVTGALAGCSSDGGDGSDGSDGSDGSDGSDGSDGSDGSDGSDGSDGSDGSDSSDAPDEVIIGSNHPLSGSLSNTGERMDEAVRLAAMMKNESGGIESLDGAELSVISGDNEGAQELGGEVAQELIDDGASVLTGCYSSPVTSAATRTSESAGVPFVISVSVANSILQETQLNYAYRPQPPANQMAVDHARLLADEIRNAGEEIETAGLFYIDISFGQSIRDALREELPANDIEIVAETAYQPGDTADTQVTTLRDADPDAVIATTYRSGTIELVNAMDNQDYQPNYLTGCSNAAMNDVSALEEMGDTVEGGFATNFALDPTSDAASEVRSRFESEFDSGFDANVAMTYASTQVIIAAIEEAGSADPDDINDALGQITVEDHIAAMPPITFADNGENENALAPLFQIQDLQDRVVAPEQFAETDVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS61</accession>
    <name>V6DS61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate ABC transporter membrane protein 2, cut1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C450_07242</name>
        <name evidence="6" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="85"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="302" mass="32116" checksum="3E07B31A89AFF0B7" modified="2014-02-19" version="1">MAADDAETGSDGFFSSLAGSDKLHRTTFYLSTVAVLLIALFPFYYLFIIAFTPAGSTTEAGLLPAGFDASSFVEMFQVLPFHRFVLNSLVIAIGVTAFVLVFASLAGYVFGRMEFKGKRPLFLLLIAVSYFPGATFLVGLFKLLTGNVTVLGVTSPNLFNTPAAVGLPLTALALPFAILILTTFFGQIPDGLEDAARVTGSTRIGALYHVIMPLSAPGLVTAGILTFITAYNEFFFSQLMTTGAAQDWSPIVWGLTNYQAEFSIRYDLMAAASIVGVLPVAVLVLLAQRKIVSGLSSGSLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS62</accession>
    <name>V6DS62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075926.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="122" mass="13625" checksum="F84529A927A7167F" modified="2014-02-19" version="1">MDTITVEAFETLDRSVTEVNTDPEAYIEVEVTRKEAVDVDDALSSLLKEAIDGEYGNAEQVSDFKRLWQGRCRGSPTIMITSSEEADIALDALDRFEAEEVDLTDRIHDDLVEVINETGVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS64</accession>
    <name>V6DS64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5189" checksum="41A0A2994D60CEEB" modified="2014-02-19" version="1">MEFEAQRESPTGDRVARADNGNLPGSVRWSPAYGVVPKNSRDRSGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS65</accession>
    <name>V6DS65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5055" checksum="9642A48AEB39D15A" modified="2014-02-19" version="1">MSSSAVRPDDTTVADLQAHYIPTLVILSIDGSAIGISKRARWPAMIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS67</accession>
    <name>V6DS67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_00260</name>
        <name evidence="3" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076232.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109702at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="17221" checksum="64F3EAEFE78CA70E" modified="2014-02-19" version="1">MTLVVVPVRFPPSSHSAATLREAARVAQERDADLTILHVDLYQRSGGVSRSDLKRAVEERIGRLDRARYVVRRGFLVEETILEEVVAEGADVVVIGSKQAGRWRRMVQKLLSDPDIDSFLRGELDCTVITVDADGETTTSETSTDDAAPLPDDAGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS68</accession>
    <name>V6DS68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="14688" checksum="B24D976805E32DB4" modified="2014-02-19" version="1">MVWGPARGAHAAGGPTSPCKAFARIAGCKADAEVGVRLAGDARIHGTVGVHTGYTCFGRVKGCVRRVRTTRRIYGENPSSTMIRRCLSMFPDYSSAFETAAGDSLMTALGQRYGWRTLATIAFSETYRIMYTKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS69</accession>
    <name>V6DS69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4707" checksum="0CB683CC450B5FEF" modified="2014-02-19" version="1">MEHVAMYLFVLLDHFERFEDRGKAENSLATLAINRLRSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS70</accession>
    <name>V6DS70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="11066" checksum="44FAE2A53F559A49" modified="2014-02-19" version="1">MTTQDSEGTDRCRETTGHQNVPISASYGGTTFHLYQLVYTPDPRDKHYPKAWVVVDLQGRLKLSDLRFDESKSLTEEEVRNSRITPETAATGTPVFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS71</accession>
    <name>V6DS71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbsB-2</name>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="490" mass="53581" checksum="B65D4B2917486056" modified="2014-02-19" version="1">MQELIGVNRRRFIRTAGATGVGASIAGCLGGENGSDGSDGSDGSDGETTLQITLLSQMTEQAINGFEPALKEAGLSEDITFEINTATPGQLEQQYRQWLNAGRGDPDILLMDVGWSIPFIRRGQLLNLNDHFSGDEIDTLESEFKGPSVDSSRGRDGDLFGVPFIMDVRGVMYRKDHAEAAGYDPEAESWGSEPMSWGEFSQIVSDVKQQQDLEYGMTMPFELSQTITCCAFNGMMSQWGGTYFGGRDNLFGPIGDRPVTVDEEPVLNALRMLRTFMHGHDDEHSLDESEFAGDIVPSEALGWRYTTDMESFIAGDAFAYTVGQLGLLQQIAGSVDGDVNDVIGMIPYPYGIEPSESEYAGLGGSVSPLAGYNLSVNPNSDKIDAALDVLRVVLTDEFHRSYFEVSGSLPPKPSVFESEALTEHEMFGQYLDTFRIAAENPVPRPVTPIYFQQADIIAQEVHNVVSQGKPPEEGMVDLKEQLEQIEENNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS72</accession>
    <name>V6DS72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076235.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="21034" checksum="D100C2B7BD0E6A4E" modified="2014-02-19" version="1">MTTEASLRERLFGCAVGVEYSWRQRYLDTTFEAFDNRIIERIEERESVRVGEYTNTLIELCENAIEANFRLTIEKESAEILEERDVFDQYIPFSEVNDDTHTREQAMIMKALDECEPVYSWLLKIETDPHLRYRWGRYRTMVNLCQYLTSIVEEWCFDELDRSGRRTSGSVLLFGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS73</accession>
    <name>V6DS73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_08805</name>
        <name evidence="2" type="ORF">BN903_310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076735.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130676at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="6718" checksum="02946132F44FA49A" modified="2014-02-19" version="1">MEIGFELGANVPSGVFALHAAVAVVFLYLAAVNATNGETVGLALYLAMAGMIALVGLVAGRIVSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS74</accession>
    <name>V6DS74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4806" checksum="6EDBCFB13C5AC3EA" modified="2014-02-19" version="1">MDALVCRCAVRSNGRDVRVCGHGVCGEFVVMMCAVSLRSSSARCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS75</accession>
    <name>V6DS75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IclR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C471_08745</name>
        <name evidence="6" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076935.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82473at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="5">
        <location>
            <begin position="73"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="259" mass="29117" checksum="2C249802F96FBE16" modified="2014-02-19" version="1">MTDNDTDSSGRQIDAVENAFNIIESIQELEQCGVTELADQLDIPKSTAHIHLQTLRNLGYVVKEDGKYQLGLRFLELGGRVRHNRSIFQAARSEVDELARSTGEVGTIGYEENGQRVLVYRTEPFEGVSDNAPTGEFTRMHWTAVGKALLSQRTDDEIRDIVDRFGLPRATENTITELDELLNEIDEIRTQGYSIENEERVQGVKSIAIPIRDDANQAGNSAISISGPKHRFDDERIESELLSALRNAANVIELQYKHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS76</accession>
    <name>V6DS76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4386" checksum="C413FA49093FAFF1" modified="2014-02-19" version="1">MTTTTLPIESLLEAAGIPSDASIHDFEWTDDGLEIEYSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS77</accession>
    <name>V6DS77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyrrolo-quinoline quinone beta-propeller repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_00295</name>
        <name evidence="1" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5436" checksum="0891D4D3A4066CA3" modified="2014-02-19" version="1">MRWYYHIDGFDVTFTTPPVLVDGAVYVTANTIDAVGALGDVPQSEESGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS78</accession>
    <name>V6DS78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C469_13685</name>
        <name evidence="7" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076791.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66651at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="35063" checksum="AAB7F3F0428E923A" modified="2014-02-19" version="1">MLSSFFLDACCREAAAVSFAGVPAGAAGALGGLAALAGTLDSAGMTAVLGLSLPNPTILAQYFVFAVLLGGIYGLVALGLTMIFGVMDVINFAHGALMVVAMYAVLVFSDATGLSPFFAIPFAVVLLFVLGVLVYRSTIAPIIDAPQENQLIVTFGVLLILVSGVEMVFGSDPQQLGLDLGSLNISGVFVPQGQLYALIIALVALAGTWLFLQRTMLGRAIRGTADNRDGAQYVGIDVPRIDALTFGIGAALAGLAGGVIPLFQSFTPALGDQYLINAFVVVVLGGLGSFPGAFVGGLIIGFIQVFGSAYLGGSTYQIVIFLAFILVLLVKPEGLLGGSADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS79</accession>
    <name>V6DS79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mannonate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C471_08725</name>
        <name evidence="4" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076802.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00632"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008927">
        <property type="term" value="F:mannonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006064">
        <property type="term" value="P:glucuronate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004628">
        <property type="entry name" value="Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30387">
        <property type="entry name" value="PTHR30387"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03786">
        <property type="entry name" value="UxuA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="366" mass="41307" checksum="959C64B8CC354897" modified="2014-02-19" version="1">MTQDHDITQQDRPKTETDQLPLRTGLRTRTLSDDRLAFCRQIGVEDVFLDHRSPRGDVFEDEGSGDDETITIDDGVVPSVSELVQARRRAEDAGLRLMGIQSLSYNVYGKIMLGKDGKESQLDTIKRLIRNLGSADIPILGYQWNPRGVVPMRTSQTVRLRGGARGREFDIDDLDAPYEPVDDLEREYTEAELWDNYEAFLEEILPVAEEAGVRLALHPADPPTVEQLGGIPRLFRNFEAFRRAMELVPSDNHGLKLCLGCFSEMPDADIEEVISYFGERDEIVFVHFRDVVGTWPRFTETFLDDDRSNFNPAAAIERLREVGFDGVMVPDHVPEVVGDTEWGHRSRAHAVAYLNGILSCTEGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS80</accession>
    <name>V6DS80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C471_08715</name>
        <name evidence="3" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076804.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="56373at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="13"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="483" mass="50978" checksum="9A1A85EA5A23BCE1" modified="2014-02-19" version="1">MPIASENYVDGEWTASETGETFAVRNPAEPSSITDRFQASAPGDVETAVEAAVDAQEEWADTPGPDRGDVLKRASECLEARKESATEKLVREEGKTRSEAAGEVQRAIDIFAYYAQKCLDLGGISKSASGRNTELYTKREPLGTVALITPWNYPIAIPAWKLAPALAAGNTAVIKPASAAPGMTAVLFECLDEAGLPDGVANMVTGSGSDVGTPLTEHDDVDGVSFTGSTAVGTSVARSAANDLKRVQCEMGGKNPTVVMPSADIDEAAEILGVGAFGTTGQSCTAASRAIVHEDVYDEFVEAVVAYADGVAIGPGLDDPDMGPHVSESELESTLEYVEAGEDEDATLETGGERLSGGEYGDGYYVEPAVFSDVDSDMRIAQEEIFGPVLSVIEVSDFEEALAVANDVEYGLSASIVTQDLTEADEFVDRVEAGVAKVNEKTTGLELHVPFGGYKNSSTNTYREQGDAGLDFFTSTKTVYRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS81</accession>
    <name>V6DS81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase ISHwa3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_07104</name>
        <name evidence="2" type="ORF">BN903_268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="110"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="276" mass="31053" checksum="12684A4DBB9B8948" modified="2014-02-19" version="1">MTQISRFIGEVVPVAQRVTGDGGESAAPEGGGGFADYALVSLHCLRIYLDTSYRMTIDLLKEMPQIIGEIGLDAADLPVPSTLCKAFDRISMSVCRVLLRQSAQLHDLSEHAAIDATFYERSAASRHYCQRISYHVQKLKVTKLVDTASQAILDVHCSTNREGSDADLAEQIARRNAGDLRSLAADKGYDKQSLREGLRDLGIRPLIKHRIFAPYDHAHNARIDDNRYNQRSMTETVNSAMKRSLGFAVRARSWFREFREIALMCMVYNIKRFVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS82</accession>
    <name>V6DS82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_00793</name>
        <name evidence="7" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="13586" checksum="D90A1F83D14E1620" modified="2014-02-19" version="1">MFRILGYGSPVLLAVIAGVLQFVPVVGPSVLVVGLAAGDLVVGETARAVAVLVLGLVVVSFVPDAVIRTQLAGRTGRISPGLYFVGFVGGVLTLGAVGLIVGPLVVSLLLEVIDMLSEHDAPGSSIEERADSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS83</accession>
    <name>V6DS83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8538" checksum="B24865A6DCAC07AE" modified="2014-02-19" version="1">MDYQIKYVLNVYSENRNITLPADNPEKPIRLSTIHRGPIVQQYRTTIDMNYSSTVVMVPESVAPGLEFDHGRGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS84</accession>
    <name>V6DS84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C451_00700</name>
        <name evidence="1" type="ORF">BN903_273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075946.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86309at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="437" mass="49491" checksum="588058BC487A6779" modified="2014-02-19" version="1">MSSAWPISIQPPFADDCWAIVRARFLDAQYWEADSKQAAIDQLKGGIDDPRDVPGENPPVTRQTVAIDAHEDFANSITLGTLFENQVGLASFGEATAEKPWFKAQPERNQLEPLYDSDRVLHATSGDGPADHPSEWEWEYALWARHASDNEFDVVLHRPERYEWTTKTAETSELIRILQGRWHTQGSAHLKQFYFEKSHEDTDDPYLAWEPAAGEYHPESESPFDPSWDFCPGAPMAINGWEYDPHARLSREVWRSTTTPERRVELHHNPSDYSFLKVFDSRVSGADAAMVPDGFDSKVQSTTLASDLRDKAVRWMRRHSPGGVAHPAFDAQLLETPAGWVLDRSPGVRYGAEFHVRYRKETPPDQETDVFIEIAGPSKSTDFRVTRIEQAGETGRKTTESIPTPEHCSPIVAHSRFRKFVRSNTESPADDPTRAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS85</accession>
    <name>V6DS85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol-3-phosphate-transporting ATPase</fullName>
            <ecNumber evidence="8">3.6.3.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C493_00055</name>
        <name evidence="8" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.20" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076795.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="391" mass="42877" checksum="C0B445ED18753BB4" modified="2014-02-19" version="1">MTHLKLDNVTKEYSDVVAVDGMNLDIEDGEFISLIGPSGCGKSTTLETISGLTKPTGGHIEIAGNDVTDAAPKDRDIAMVFQNIALFPHMTVEENLTFGLRLKNYEQEAIDDRVSQAADILQIEGMLDRMPDELSGGQRQRVAIGRAIVMDPEVFLMDEPLANLDAKLRVHMRTELQRLQQELDVTTVYVTHDQAEAMTMSDRIAIINHGELQQFAPPLECYNEPANLFVAGFVGSPSMRFVQGEVNDGILTDSKFGITLDTSSSVKIEDNRQISLGIRPEDVYLANNETVGNATEPIALEVDVVQPLGDKLMVYLRAPDSDLTFESDLDETDQTTSKTDQLLMAVDPSADIEAGQQIDIVLDRSQIHLFDSASGDALVHSLEQKAESVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS86</accession>
    <name>V6DS86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C471_08705</name>
        <name evidence="3" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334920.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42639at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="13"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="414" mass="44091" checksum="450FD3C8F9510A98" modified="2014-02-19" version="1">MSESYSASFNWSKLLTLVLIGIIPSFSGALINPTIPAIQQTFSHVPNSETLAQLVSTTSAWIVIVVAPLTGYLLDKYARKPILIAAVIIYGAGTSVAFFLDSIYLILATRILDGIAVGALMVTVPTLIADYYSGGRRESVMGYYGAVQAGGGAVAAVLGGYIAGTLGWRYIFLVFGGALLFVPPILRLLPEPDVKESQRDDEISRLEAVAKIVRESPVKVIAGIYFLVIFGMLTNNLIMIEVPYFLQDAHAVSDSQTGLIISGVMIASVVMASMYGRIKQHFRHITLVTAAFTFAAAGFLLFSSAELFPVVLVGIIVAGGMGMGLLLPTVNDWVASIVQEEVRGRALSGVTMMMYGGFALSPFAPMPLVDAFGRVGMLRTTGFLLLIVAGALVTTWFVSRSTAPPTPDGTLSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS87</accession>
    <name>V6DS87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_00247</name>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076248.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66988at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12942" checksum="438425F9CF4A6EF8" modified="2014-02-19" version="1">MPTAFPYRTPVDHTPHERTNVVVDDDQPSDILQTVSSDTAQQILATLDGEPATTSDIAEAVDTSIQNAKYHIEHLCEANIVEPVDTWYSRKGTEMTVYALSVEEIVVQLGGSISETQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS88</accession>
    <name>V6DS88_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_03990</name>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5193" checksum="E457158F75118CE7" modified="2014-02-19" version="1">MRDVDQTLGEESAYECFECGNVVVAEDNPGSCPDCAGEMRNRRVPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DS89</accession>
    <name>V6DS89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C483_02690</name>
        <name evidence="8" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076807.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106494at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="7">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="7">
        <location>
            <begin position="103"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="22090" checksum="3BCD6A9EEBF26299" modified="2014-02-19" version="1">MSQGVISILFGDPFAVMNTIGLVAFALVGSSKAIREEFDLFGVAVVGLAMAFAGGTTRDLLVARVPLVLQSPIEISLALLGVGLAVSLNALLSSPETHPVTLVSDAIGLAAFTTAGAIVATETGLSAFGIVAVGTINAVGGGAFADILLDRSPFILFEDFYASCAVLGGTAYWLVETIGGAGGTAAVICAVVTVGTRLVAVIYNWDLPTAQNIGTQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX8</accession>
    <name>V6DUX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C469_13665</name>
        <name evidence="5" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076794.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82473at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="72"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="258" mass="28034" checksum="10706AD284DF792A" modified="2014-02-19" version="1">MTRDGTPNAAAVGATKQSFAILEQLGEQEGCGVSELAESLSVSKSTVYNHLQTLRSLGYVVQDGDEYRLGLQFLGLGDRARQHHDLYHVAKPETDSLVEAVGERAQVMVEEDGTGIYVYQSLADQAVRTDSHIGTVVDLHATSVGKAYLAHLSDDRLDAVLDRITFHGQTPDTLTDPEALRTELDEVAERGYAFNDEERTVGMRAVGAPILSADDGRVLGAISVSGPTTRMNGTWYHEEVPEMVRQSAQIIGIRATYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB0</accession>
    <name>V6DWB0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PadR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_2836</name>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078033.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88437at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15881" checksum="7EDA3EC883DB9378" modified="2014-02-19" version="1">MSTDLETTGDMESRELVHFVTQQTRFALINNILQHPKQLPSMYELEELNPSVSEATVYKHIQKLIDAGIVREVPLDDDQRRQGYPWKFYGLTAEGRTFLDEHNLLAAEETLQQIYETISNKPEKMVKYENAPRPDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB1</accession>
    <name>V6DWB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11678" checksum="22A4857B3CBB0E03" modified="2014-02-19" version="1">MERAQNAEEYSGASEYIRVMVSAGESNIAALDPRTLDDSTSQHGNGEQNDLDKLIFEALDDNYAELDEILNNGLQQQISDRLLELAQQDDLPVEKNGFEFKIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB2</accession>
    <name>V6DWB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5445" checksum="05DC4E013C97F280" modified="2014-02-19" version="1">MRASSSTCPSSRASVDVLTEWVPVRATSSTNTNNLCQLKLGDYSSQVCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB3</accession>
    <name>V6DWB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4884" checksum="D0756AE7A33F90E6" modified="2014-02-19" version="1">MVPSGRGPAEQVRAQAALWAVHPPESDPLSGRRPNRYSCQRPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB4</accession>
    <name>V6DWB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5799" checksum="E9422DA3DB2DFB25" modified="2014-02-19" version="1">MTDYTEDVVVEARVPVEHAEYLEEWADVVGCDVADVAGDSISQFLEEQPIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB5</accession>
    <name>V6DWB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_10865</name>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="22492" checksum="168C882EC5AC147B" modified="2014-02-19" version="1">MSEETPPSNQVRPDGGAEQRDINDVVVEDWIEETTPFERVYEIIRSTYDPTSASQIADRARVSPTTARKHLRSLVDTGEVTTSQDGQTTLYRRSETGIVTEHAQSLLAERTPEEIASGITELKAQIQNWRDEYGVDSPEELARELDIEDADSESGTLLREWQTTRRNLALAQATLAIAEASRTGHLTGTDTDDDSNSDSSIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB6</accession>
    <name>V6DWB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C485_17777</name>
        <name evidence="1" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078025.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130397at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="18282" checksum="B7BC59E5CBF4B30B" modified="2014-02-19" version="1">MSKSKAVDTLLQEWREKANVLKDRPEEIKEQQDSFYKGSWDAARERAEPELRRKAIQACIDDLEESTTTDDMLEALADWRKEADKLDKRIYDSQEWFRSNITRHQLEKCIEEFEKAFPDDNFNECFRCGSLQLPVSDKRRNKGFRWECEECGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB7</accession>
    <name>V6DWB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11115</name>
        <name evidence="1" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="13059" checksum="0A90003765917944" modified="2014-02-19" version="1">MGNIVPDGLSATRPISPHLSLSFLPMPANDPLDDVALNTYEVSVPIEFDAFETTEAASLTVAETVAQSIVAEVDELSDDDVSYVSTQVSFDMDGLEDAFDDDEIEIATVQTRTELAVMDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB8</accession>
    <name>V6DWB8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C473_08642</name>
        <name evidence="8" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="7">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="22248" checksum="E3FC24EAA981238E" modified="2014-02-19" version="1">MRVIAVLVESQTFSPVAPDNAVFLPESAFSADGYAQALVIADSGAQANAAADAIREEVNAREDRVELFELAALVDEINEFFGLLSTFLLGLGAISLVVAGVSILNVMLMSTVERRQEIGVMRAVGVARRDVLRVLLAEAGLIGAVGAAAGTLLTVLLVAGLVLATPAVDAALVLDPTNGYYLLLALGFGVGVGIVSGAYPAWKAANERPVEALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DWB9</accession>
    <name>V6DWB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage head morphogenesis protein, SPP1 gp7 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C490_06204</name>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006528">
        <property type="entry name" value="Phage_head_morphogenesis_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04233">
        <property type="entry name" value="Phage_Mu_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01641">
        <property type="entry name" value="phageSPP1_gp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_Mu_F" evidence="1">
        <location>
            <begin position="204"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="35467" checksum="F10883F075FA4A97" modified="2014-02-19" version="1">MVRRIRAKSDSNAQFVSSLSAVSVARGIASQLSILHQHTPVPTTDPTRTKTLRDAFGSDASKRFRSIKGDVRESVEELDILQLGTQRAVNSAPDPREYEFLSNPEKRQRFQAWLREQVDNGVLETTSGRAVRRGEHWTAQYVQKAYAKGVTDAGAKIRQQGGDAQVLENLEDIFNQPVHSSKIELVYARAYDGLEGITQEMDTQISRELSKAISQGWNPRKAARKINDRVDKIGMTRAKTLSQTEIIHAHAEGTLDRFESEGFTEVEADVEHHTAGDSRVCPKCASLQGTTYTLEEARGRIPIHPRCRCTWVPIVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6E001</accession>
    <name>V6E001_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_15924</name>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078296.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91988at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="15755" checksum="82D67510F3499E8D" modified="2014-02-19" version="1">MDVINPVMWSVHVGFAVLWVGSVLFVTLAVLPPALRGDIGGDALGSVVGRLRWITRIAAVAFVLSGGHMAGNLYTFEALTGTPRGHLVLTMLGLWFVGTGLVEVAGSKLADGLDAGKLREPARDAKPFLYGASAVSVGLIVTAGLLASPTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6E003</accession>
    <name>V6E003_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine thiazole synthase</fullName>
            <ecNumber evidence="1">2.4.2.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_03541</name>
        <name evidence="1" type="synonym">thi4</name>
        <name evidence="3" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycine + hydrogen sulfide + NAD(+) = ADP-5-ethyl-4-methylthiazole-2-carboxylate + H(+) + 3 H2O + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:55704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the THI4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.59" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078291.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61905at2157"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00304">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022828">
        <property type="entry name" value="Thi4_prok"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>glycine</name>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="311" mass="32455" checksum="16D59EE1DB380A91" modified="2014-02-19" version="1">MDGFNGFADVSETDVTRAIGTEWTDGFLDFTDSEVIVLGGGPSGLMAAKELAERGVKVMIVEKNNYLGGGFWLGGFLMNTVTVRDPAQEILDDLDVDYEPVDDVDGLYTAPGPEACSGLIKAACDAGARVQNMTEFTDLVVREDHRVGGIVMNWTPVHALPREITCVDPIAVESDLVIDATGHDAVAISKLDERGVLSAPGIEHAKEHNTGMDQTGDGEYGAPGHDSPGHDSMWVGESEDAVVEHTGVVHDGLIASGMAVATAHGLPRMGPTFGAMLVSGKKAAQTALDELGSDAPEVELSTGGAPAPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6E007</accession>
    <name>V6E007_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_03651</name>
        <name evidence="1" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078302.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108043at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043900">
        <property type="entry name" value="DUF5788"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19101">
        <property type="entry name" value="DUF5788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="145" mass="16734" checksum="B2EC5A1358D4DCE0" modified="2014-02-19" version="1">MKGYERKQLLERVNRESSTVGVEIPESIEIQGEEIDLRSFVFEIKRRDSVPPGERDRVDRAKRNLRRERLDRLEPIEENEVSREEGEELAASIIGIDRALEALEGLDAPDPETEAKRQEAADQKRWMNFLQKALGREDGGGRTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6E023</accession>
    <name>V6E023_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06868</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078308.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100430at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="29"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14568" checksum="946738BBCCE78D76" modified="2014-02-19" version="1">MPTVEYLNYEVLDDHGWSMDDDDLFEEAADADLDDEDYGTLEVNQGEYILESAEAQGYDWPFSCRAGACANCASIVKKGDIDMDMQQILSDEEVEEKNVRLTCIGSPATDEVKIVYNAKHLDYLQNRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6E024</accession>
    <name>V6E024_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MazF family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_08060</name>
        <name evidence="1" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078313.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100836at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="117" mass="12875" checksum="59BF79FBCAE5338E" modified="2014-02-19" version="1">MSDDTDVRRGDVVIVRFDPAEGHEMKKTRPAVVVQNDIGNRNSSTTIVAPATGTYREYPFEVFVEADGSPFEKNSSVRLDQIRTVSVPKRIHTVVGSLDGPTMAEVDEALKLSLDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6E026</accession>
    <name>V6E026_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4334" checksum="BFF94DACB01642B0" modified="2014-02-19" version="1">MRSVASTFINTRYGPTADMCCPLLPTVFPEDRSVYYQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6E027</accession>
    <name>V6E027_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pterin cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06788</name>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078317.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95226at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="148" mass="16439" checksum="13D8F1FB6CBEF484" modified="2014-02-19" version="1">MAQTSEMAEQTAETESVSGEAGATATEAETTVSVRCTGHVRTELGEYEFEYTFEGDTLRAFLDELFEDYPELQDMLIAESESDATHSGWAPTPEELPGTWSKNPVGEQTIAYARILVNGHFNENENGFDTELEEGDRVALVYPFMFCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN1</accession>
    <name>V6DQN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5226" checksum="711E0342C96FD4A2" modified="2014-02-19" version="1">MGIPPRHSVLTVRKTAMAPPAEKRRPIYSRRRRTLTCVRPYPPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN2</accession>
    <name>V6DQN2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative nickel-responsive regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">C472_14957</name>
        <name evidence="11" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Transcriptional regulator.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="8">Binds 1 nickel ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the transcriptional regulatory CopG/NikR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006630628.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010045">
        <property type="term" value="P:response to nickel cation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00476">
        <property type="entry name" value="NikR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022988">
        <property type="entry name" value="Ni_resp_reg_NikR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0533">Nickel</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RHH_1" evidence="9">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="NikR_C" evidence="10">
        <location>
            <begin position="54"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK37860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15986" checksum="B3BB802E0738DAEE" modified="2014-02-19" version="1">MSVVSVSMPEELLERIDQFADDHGYTGRSEVVREGSRNLLGEFEDKKLEGRDLMGVVTVLFDYETTSVEEKMMHLRHEHEDIVASNFHSHVGGHHCMELFVLEGSLEDISTFVGKIRATQDTITIDYSVSPVDDFGPLADIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN3</accession>
    <name>V6DQN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8965" checksum="4AC283413378BE87" modified="2014-02-19" version="1">MFVGRVDDPAVERPPREVGVDHVFGEPARVGVEPDRDDAVDRADPVRERLEEVHTRPASAGTLTVLFRERRPRPPQQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN5</accession>
    <name>V6DQN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterio-opsin activator HTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C463_11382</name>
        <name evidence="4" type="ORF">BN903_192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076319.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57581at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="171"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="233" mass="26140" checksum="27DA228BDF7C29C9" modified="2014-02-19" version="1">MLDVTMDMEQFDCPFIDTSADHDVAFSAMHWQLDTAAEQLETRLLVESPDRYELGEGLSALRDHENMAEYRLFSKQDGTAIIRTVIEETNAMSTITDHGGYITGPFRIADGSERWQVGFDDEATTEDALHDLEKGNEFVVEDRSELSMEALFDTMRNANAASTMLGACRDLTDVERETIETAADEGYFESPREATLSTLADEFDVSTAAVSKNMRRGEKKLLRSVVEALDRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN6</accession>
    <name>V6DQN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cobalt ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_14982</name>
        <name evidence="8" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006630633.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84346at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK37865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="226" mass="22914" checksum="FA1D67F4A95CCB2A" modified="2014-02-19" version="1">MPHIHLGEGSFPLWALVLWTLIGTALISTVVYRVRKGGIKTHQIALAGIGAAASFAIFQLNIPVWGGIHMNLTGLVGIIAGPLLGAIVALVVNVFSAALGHGAVGLIGANTLINASEAIVAYYAFKTLIGMDWDVFPAGASATTLGLSVGSFLMAAIIVISGVNGSALPRGDLTIAVAGLAGLNLGVAVVEGILTGLIVQFLASVRPDLVGLTDRDTQEEATGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN8</accession>
    <name>V6DQN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_06639</name>
        <name evidence="1" type="ORF">BN903_135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043851">
        <property type="entry name" value="DUF5813"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19130">
        <property type="entry name" value="DUF5813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10549" checksum="AF648E4019C2DA4E" modified="2014-02-19" version="1">MVEDGWADTFERRVVDVGGVTRREREFDPVVETDGDEIAVTYALTDGNERRGVDDAGALIDFVEGTYVQGVIPGYEYTGPVSELLSAARRHGNDGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQN9</accession>
    <name>V6DQN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15851" checksum="AFC63A43F2FC9766" modified="2014-02-19" version="1">MTFSGSRKHSTITCAALINRLFQARIYLKKRISTKPLVYKSLIDTNTAEAPVARRAHARCAPRRSLHSLLRCLLRPRPPRDCPFESRPTATAASHLPSLVAGGLRFARPPPTPSRGAPRGRRGRPLGGTRHRTADRSLFFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP0</accession>
    <name>V6DQP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12437</name>
        <name evidence="2" type="ORF">BN903_209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="210" mass="22586" checksum="FED67E24AC833D01" modified="2014-02-19" version="1">MSTPEELRETVAAATDAGFQFTAHAIGDEAIAAVLDAYEEASETDPGEARHRIEHVELADDEAIERLAETGVVASVQPNFLKWAGEGGLYEERLGPERTAETNRYREMLDAGVRLAFGSDGMPMDPLVGVHHAVNAPAEPQRLAVTEALRAYTSGAAYAGFDEDRLGTIEPGKRADFVALDASPWERSDAIDDIDVGLTVVDGEVVFDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP2</accession>
    <name>V6DQP2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative nickel-responsive regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15002</name>
        <name evidence="3" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transcriptional regulator.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="1">Binds 1 nickel ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory CopG/NikR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075810.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010045">
        <property type="term" value="P:response to nickel cation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00476">
        <property type="entry name" value="NikR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022988">
        <property type="entry name" value="Ni_resp_reg_NikR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NikR_C" evidence="2">
        <location>
            <begin position="54"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="16000" checksum="22AC8CCF50105535" modified="2014-02-19" version="1">MSVVSISMPEVLLEHIDEFADEHGYSGRSEVVREGTRTLLEEFQGQGVDGQKQMCTVTVFFEYCQPAVQQRLTGVRHEYDGIVSATTHVHVQDQYCMELYVLEGITEELSGFVNAVRAVPDVQTVKYSITSLNNVPLNQAIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP3</accession>
    <name>V6DQP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_12956</name>
        <name evidence="2" type="ORF">BN903_141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="6576" checksum="959C3B3D56C960E0" modified="2014-02-19" version="1">MGQHGLEIWTVLALFGGLSAVAVGFGVLTGFSGFGSGDDGPSGQRGKTTVALAGLALTSAAVGAGIALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP4</accession>
    <name>V6DQP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12469</name>
        <name evidence="2" type="ORF">BN903_202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5445" checksum="E39337FA0258CD4E" modified="2014-02-19" version="1">MALEALADNDRARSFYAARGYDAHRVELTKPLGDESDGDGADDDARDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP5</accession>
    <name>V6DQP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS240-type transposase (ISH102)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Halar_3353</name>
        <name evidence="1" type="ORF">BN903_214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5992" checksum="3C6EB66BBEEB804D" modified="2014-02-19" version="1">MKGDGGVSKPSIAENTRFRDCLDEINVAFVEREATPWLLLKFSVLFQLPEIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP6</accession>
    <name>V6DQP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15027</name>
        <name evidence="1" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5009" checksum="BB077E7057A780B6" modified="2014-02-19" version="1">MCHCFSELTEMSDEEQAEIVDEHSTEELRAEYSTEELESLGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQP9</accession>
    <name>V6DQP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6338" checksum="A21A44B113D12F70" modified="2014-02-19" version="1">MSPVNRRGYVLTDEQLRQLLINDGAVARASERSPLATARSTARGSQRRPTGAADEAAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ1</accession>
    <name>V6DQQ1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD_binding_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15052</name>
        <name evidence="3" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075819.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16049at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_9" evidence="2">
        <location>
            <begin position="21"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="430" mass="47440" checksum="22EAE5942114B909" modified="2014-02-19" version="1">MTTNDALEEHPAANRQPYEYVIVGGGIHGTCLANYLLTEGEYTHDEIRILDPREELLASFGKKARQCGIETLRSTFVHHIDTESFSLESFAEGHHRAHELVSTENHPDRPTLDLFLDHARDIIDRRDLDDCHHRSRVTDITRPTSQKGYLLETDTGTVEAHRVVLAVGLGVAPTLPEWTTSLSDDAPLAHVWDDKFDPTTTSEFEGRTFVVGGGITAGQLACCLAEQTDVTLLSRHELDIELTEADPYWINWRHIGKEIHTLPPGSEARLDRIRAARNDATIPPYVERRLTEACDDGTLELRRGEITSAHGTDEGLSLRFDDGTRVTAARVVLATGLEPVPERPVVERVSESLSLARGAEGFPILDDRTLAWRRTDGTDSAVYVSGALAEPSVGPFARNIVGARRAAERILDPPEQARAESLPMSSRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ3</accession>
    <name>V6DQQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5358" checksum="47CF96C0ECD2E28D" modified="2014-02-19" version="1">MTRKDGQRNFALRQLPTTEVVGLDSLAPHGQRQFNYRWAKCAPDVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ4</accession>
    <name>V6DQQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_16351</name>
        <name evidence="1" type="ORF">BN903_212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076335.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104219at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15217" checksum="E3D6B32719362E19" modified="2014-02-19" version="1">MTTLHITVGDREQLREDALQFVQDVEDDDLDDQDGKATLQFGTYDDFVDSLTPLRLELIRAIAEEAPESMREAARLVERDVSDVHSDLKQLEVLGILTLEEGGPSGAIQPVVPFDRIEVHIDYPLIDNGDADSAPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ5</accession>
    <name>V6DQQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_15072</name>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075823.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="120451at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9526" checksum="95A4CFD734BAFBD2" modified="2014-02-19" version="1">MSSPRSLFRTAVDKNAPRETRTAAIDELAEIAATTQLRVIVVADGFNGSFRRQALNGLGRCQATTELAALADDASLPTPLRERADQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ7</accession>
    <name>V6DQQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4699" checksum="C98F172D1A0DDCE0" modified="2014-02-19" version="1">MATSRYRDATLKAMNTNPTAASRVIPATSDQTVFAVSWSVRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ8</accession>
    <name>V6DQQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_01157</name>
        <name evidence="1" type="ORF">BN903_156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6628" checksum="2508CA81DF1B43F2" modified="2014-02-19" version="1">MSAVTADRPQYVTPTRVDVTECRTDRLPDRARANRVDGSEVHLERRGGRTYLVTRPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQQ9</accession>
    <name>V6DQQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_09855</name>
        <name evidence="1" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10591" checksum="2D88D1686EB28EE9" modified="2014-02-19" version="1">MTNEIDIPSEPRAAVDALANHLTATADRPVPPATNRWLGEAEAVARDATSDDLDTPTRRKRVRQVATLLESADKTDDAVADRHIEAAIECCQVALADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR02</accession>
    <name>V6DR02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075884.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121539at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="148" mass="16157" checksum="1F9AADE9DF6A474B" modified="2014-02-19" version="1">MLSSLPTRPLSVDELQSLHRSGSLVAAAPINVVLDPDQDRSRSLVVSAVLATEAFVVGVSYDPSDQTWNKVIQKENGPESEKGPDGTVESVIMEAESALEQEAERLEEDGEVGEIFGSDVEDGVNADYRDGTELNKVLQKQYDEYTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR03</accession>
    <name>V6DR03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="10022" checksum="F0FE7FA92CA0877F" modified="2014-02-19" version="1">MKCCAGWESKGQPGGWRRRRKHRKERVKRATEERSERAPSSRLGLRWSCRSLGNNQKHYRIFALPDGSDLDRPKHLTRRRQHGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR04</accession>
    <name>V6DR04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C443_03294</name>
        <name evidence="1" type="ORF">BN903_309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076396.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101018at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021799">
        <property type="entry name" value="DUF3368"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11848">
        <property type="entry name" value="DUF3368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="18269" checksum="5E21A0EA00462057" modified="2014-02-19" version="1">MRNSGLVVSDTSPLLNLALIDRLDLLQSQFSDVTVPRQVWDELTDGQDGLEALRELRDDGFLHLVEVERSDLFVELFHELDLGETAAVCYAVEENADLVLLDERDGRRVARRHDLDVTGVIGILLRGAKTGEVNLQHELDALREAGFWISDNLYEQILSEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR05</accession>
    <name>V6DR05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CopG/Arc/MetJ family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01943</name>
        <name evidence="2" type="ORF">BN903_302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076389.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95679at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="148" mass="16928" checksum="537DF6836CA2C390" modified="2014-02-19" version="1">MVKSTVRFPEPVVEEIESLVEEGQFESKSEFYRFSADYVLSRTLDEYEPETIDYDAIEAEVIPAEERELGGDGDDDGPPFFDSVAFVRKLALRGKFSDAEDFIDHQYVPGDRHAVLLEEILQLYREDAATEDRPPAPEHDPEPTTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR06</accession>
    <name>V6DR06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator PadR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C491_15492</name>
        <name evidence="2" type="ORF">BN903_205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075887.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="11808" checksum="D7E9CE3FE9528315" modified="2014-02-19" version="1">MEELTSFQRDILHVIAGLDRPHGLAVKHELEDYYGKDVNHGRLYPNMDQLSEEGLVDKSKRDERSNIYVITELGKEMLAVRHHWQKSYFQPSAKLNAAVQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR11</accession>
    <name>V6DR11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4795" checksum="BC544CA3E8307A7E" modified="2014-02-19" version="1">MAHSSKPTFALITLGMWTGGFLAFVLAFLYVVFTDLLTLAMAGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR13</accession>
    <name>V6DR13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8231" checksum="761E9BB93A58E1D7" modified="2014-02-19" version="1">MVVNGAFPHLQPVRQLRHSARLAVHQLLDQREGLFGGSNRMFCVHTDQLRHIAVINVLDNRTKMRSLAAVDAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR16</accession>
    <name>V6DR16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075897.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="138967at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="184" mass="20960" checksum="DDD89AC8509FF974" modified="2014-02-19" version="1">MSFEDGSEPMQDPFSEEEGGDDTELEPDEETEPVEDTTDEQSTTSGTEQAGTRTTTAEPAPKVDQDSARGDRTDVPELGDVDILRRYSPEEIAQLLMDREYHEEDPQVPYAMWRDGTSTGRSRTTIELNPDLDDLVKTVRREFENRYDAEINKADVREFAMIYGLMNADDLFEMAEEWGLQFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR18</accession>
    <name>V6DR18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4925" checksum="E2ACE631C8245158" modified="2014-02-19" version="1">MCETDVPELHSTGEDRVSRCHRHGEAYADPTARRAESDETPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR20</accession>
    <name>V6DR20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_08033</name>
        <name evidence="3" type="ORF">BN903_317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="14724" checksum="978D9A21C94D774B" modified="2014-02-19" version="1">MLVLLTVGGGVIVLAARPIAGVFSPDPAVVDHATTFLRVSGLSFGFIGVMRAYTGGFRGAGHTMIAAVISLITLGFVRLPVAWVAAGSLGAMGLWIAFPVSNVVGGVVAYLWFNRDTWRDGNLTEGGPPAEEIGPGVASPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR21</accession>
    <name>V6DR21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12181" checksum="9914EFE8DFAD28DC" modified="2014-02-19" version="1">MAIATAIETDGIKDTSNVEWDTDELTVDTVLPVNDLAGGEAGFEVEASTTATESKQITKARKNPPGKAHPAEYRNHDVEVHVQIQFFPSRNDNLGGAEGMVQTEGGVPAPPGCGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR25</accession>
    <name>V6DR25_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_10723</name>
        <name evidence="1" type="ORF">BN903_329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076413.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119382at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16365" checksum="49E5DF929621B90A" modified="2014-02-19" version="1">MGDDSATAWTQVLDEMTAISSELSADGWETLASPAGDTGVTAGDDGSLDPGFVHVIPDDDADTFAEWFAPDGFERTEVYRATTPDQLYLLTVLFDDPSERAILVAGAVDRGSLSACRRAAEEVGHVHTHVRRLNGTHLGSFRHADPDAFFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR26</accession>
    <name>V6DR26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TATA-box-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tbp</name>
        <name evidence="4" type="ORF">BN903_225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="PTHR10126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6571" checksum="F967261A6739CFC4" modified="2014-02-19" version="1">MEAVEYEPEQFPGLVYRLSEPDVVILLFSSGKVVITGATDVSTPPKALEAAHGKLDSLGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR27</accession>
    <name>V6DR27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transporters inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C464_10733</name>
        <name evidence="7" type="ORF">BN903_327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="35"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="27572" checksum="DDF3CB5D22612B2E" modified="2014-02-19" version="1">MENVGPGSYDQFDRFHPFGTLTDGKDLLTFLVHGARVSLVVGLLSVGTSTVIAAAFALISAYYRGVADLLLVVTSDTVMGVPRLLLLILLTVLLADTSLAGAYNGGVLLALILAATGWPFLWRAFRGPALQVSEKDWVDAARNYGQSPTGIMRYHMLPYLVGYLLIYSSLVLGGVILAIAGLSFLGLGITPPTPEWGRAVDMGREYVATESWHISLIPGAMVTLVVIGFNAVGDALRDAVDPQSDTGATDASETESRGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR29</accession>
    <name>V6DR29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6034" checksum="CF9EB7B3D82E2575" modified="2014-02-19" version="1">MLVTLPACTRIWKSGIGSPFTQSKEIASRKTVSDLRLLRYGSGYLKKRLGQSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV0</accession>
    <name>V6DUV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4170" checksum="AA19EBAF336703D1" modified="2014-02-19" version="1">MTQGVTGAFRWGLRARSKQKRGGDAARARTIYLSFASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV1</accession>
    <name>V6DUV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome b/b6 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10419</name>
        <name evidence="3" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077477.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70323at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="2">
        <location>
            <begin position="30"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="30510" checksum="ECF21C3689CEFEF1" modified="2014-02-19" version="1">MSLKKQDDMDHNAWLKSQDLTAIETVFLTTLIWLDKRLRIVDYLELLETMYYRANLQMPKSHTEQYDLDNKFWYWYPLYSLGSLSIIAYLLAAVSGAMLGFYYAPSTAGAAAQGDPTAAYDSMVMIMKDVQFGFMLRSIHRWAAQFMVAAVFLHMLRVYFTGAYKEPREVNWILGVVLIALTLLFGFSGYVLPWKQLSFWAAQIGVELALATPLVGEWAAQLLFGGFTLGQATLVRMYILHVFVLPFVVTALIAIHVGIVWVQGIAEPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV2</accession>
    <name>V6DUV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligopeptide/dipeptide ABC transporter ATPase</fullName>
            <ecNumber evidence="8">3.6.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_06039</name>
        <name evidence="8" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.24" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK39999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077521.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41087at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="34"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="452" mass="50229" checksum="1F436172A9695ED0" modified="2014-02-19" version="1">MSEVGPPESDPEALLQVRDLCKHFDNESGLFAGVQLDDEFPYVSRSTSDVRAVDGVSFDIKEGETLGLVGESGCGKSTLARTVLRLLEPTSGSVYFQGKDLASLSGEPLRRMRKDMQMIFQDPQSSLDPRMKVGPIVEEPMKAHGMLDEEGREARAKELLEKVGLDPQHYNRYPHAFSGGQRQRVNLARALSVNPDFIVCDEPVSALDVSIQAQVLNTMEELQEEFDLTYLFIAHDLSVIRHISDRVAVMYLGEVVELADKEELFENPKHPYTKALLDAIPVPDPRSGGRKALLSGDVPSPIDPPSGCRFRTRCPSVIQPDEYDMTDEAWRNVVKFQRAVERRAFEETDPNALRGRYFDDATPSGDAGTLLDEALGHIERDEWDDAERLLAERFTDESVCATSNPAYELGSELGDDRHYAACHLRRDEAVAAAVDESAFDDGVRAGRPEADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV3</accession>
    <name>V6DUV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_11651</name>
        <name evidence="3" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077451.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51434at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039967">
        <property type="entry name" value="MJ1020-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40517">
        <property type="entry name" value="PTHR40517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="94"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="292" mass="32225" checksum="EAC4533DD135BFE2" modified="2014-02-19" version="1">MTDQADDERDPTAGDVADADAEIDPDADRHYDPDADHAFPDERLNEVLERLLSDEEIVAYLEAQNVNPVARKGYNDHGTKHVEIVRDRALQLYDLLKSGGVEFNGARQQGLDEADEPVIVALAATLHDIGHVVHRHDHPYYSIPLAADLLDDLLPAFYDVAEQVRVKAEVLHAILCHHTEEQPLTLEAGVVRIADGLDMERGRSRVPYEEGGRGINTVSSQAIERVSLREGDETPVQVVIRMNNAAGVYQVDSLLKAKIDGSLLEEKVRTVAINTHSDGVDGNEAIVDRIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV5</accession>
    <name>V6DUV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4473" checksum="F8A3F1D04DF0F9E6" modified="2014-02-19" version="1">MSSREPLCINLRGILSILISRWGGVYFQTHLQVSREGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV6</accession>
    <name>V6DUV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03066</name>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="196" mass="21004" checksum="40AA64966917D3BB" modified="2014-02-19" version="1">MEDTSTRSESESPPEEPADPASDGSGDPDAETENGGSRPTASDGASEDETDIEALRERVESEYDFDDFGPSDMAQMSAEEWDAAFDPDTWITGDRLLDRVDAELKSRIATRDVFGVLERVREDGEERILVYSDGGVRDHPAPPARCAARGRSSATSEPVVALAAYGLLRGARAARRLVASPIRTASRRGPASSATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV7</accession>
    <name>V6DUV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_15256</name>
        <name evidence="1" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004598402.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38949588"/>
    <dbReference type="GeneID" id="65212254"/>
    <dbReference type="OrthoDB" id="112906at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8504" checksum="C3CA7DB402561C37" modified="2014-02-19" version="1">MSEYTEEEQRILAYLTDSVTRGERYVRSKTIADAIGLTAKQVGSRLPRLAEKSDDVDIEKWGRAKSTTWRVTPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV8</accession>
    <name>V6DUV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_12621</name>
        <name evidence="3" type="ORF">BN903_297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076726.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112478at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="62"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="16985" checksum="C4DB4FB25F93C762" modified="2014-02-19" version="1">MTTQTLHPRVQIVWVLRAVLLSALVTAPFVGGVYVEYLPEWVPVAVGAAILTLTVAHALLRYRRWSYEIREDAIYLDRGVITQVRTTVPLVRIQHVDSRRGPIERTAGLASCVVYTAGSRGADVRIPGLTPEGASDLREELKRLAIRADGEDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUV9</accession>
    <name>V6DUV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07759</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077526.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113895at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="PTHR43175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="22581" checksum="484F7219C8E9F231" modified="2014-02-19" version="1">MSDHDHDDHDHDTHHEHLEAAVDERDDWARRRRKGIPTDKNLLVVACMDERIPIEEALGIDLGDAQVFRNAGGKVTDDVIRSAALTTNLFDTDEIVVINHTDCGMMSAPDAAIRDGLAAQAGDLDDADLDPSLPELTIGDADLLDWVKMTDDIDAACAAQVEYLRESAFIPDDTTVSGYVYEVESGELRRPDERIAEEISERRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW0</accession>
    <name>V6DUW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3898" checksum="90F95668AEF6D4B4" modified="2014-02-19" version="1">MRLSIIGSGDVRATVAACVTDRKHIGNVDVNADKVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW1</accession>
    <name>V6DUW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HSP20 type chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_03101</name>
        <name evidence="4" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077482.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114842at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="23"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15201" checksum="71FFC771F6B466B0" modified="2014-02-19" version="1">MSGLVETGRAALRSALERVGRGWGKVQERRPLSYDLLESDDAYLVVFDAPGVRGEDVDVTFLDHTVEVSLERFRDFYDGYNLVFPGRGVSLSSSVDLPRDADVTPEGANATLTRNGTLHVEIPKEEGSRDVDVVEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW2</accession>
    <name>V6DUW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_02851</name>
        <name evidence="2" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="23612" checksum="93C5C0D4EBEBE1E0" modified="2014-02-19" version="1">MSEYDDVCVLLPTMNEAETVARVVTDFRDAGFEQVLVIDGRSTDETRSVAREAGARVVEQSGRGKGQAVREAVRDHVDASYVLMADADATYDAADAAAMLDPLLDGNADHVIGNRFADMRSGAMTRLNRIGNRVINLAFRAIHRKNYRDILSGIPGVHPRVVRAPPSHRGRVRDRDRDGRRVRENRLSVTVVPITYRERPGGSATNLHPIRDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW6</accession>
    <name>V6DUW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_10489</name>
        <name evidence="6" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077484.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90707at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="145"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="355" mass="39002" checksum="B7C6C8DDB73F21E4" modified="2014-02-19" version="1">MSAIRSVASLVAAKLVALATAPKRFVVMVQRALYDVRTGKRSSWDVTKSVLMTLFGLAMVLVLLFPLFWITTASLAEGSRLFNTSGIFPDPSTYNLGAYRWVIFESDFFFVDGDWGYPQLVVGGSGGLLPFSFRWAGTDTGPGAVFNSLYIVSVTLAAGFGMIVPAAYAFSRRRFVARKRILYGYVLFTQIGAGLSIATLVALYSLFSTYGLTNNLFILGLFYAASAIPFNTWLLKTYMDNIPVSYEEAAMVDGASFLDTIREVIIPLTKPGLAVVLIFVWLAGWNEFIIAQTLLRPENYPLSVELYNIATEGRFSTPWTRFAAFANLFALPVAIVYFAAQRSVEDGLSFGGMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW7</accession>
    <name>V6DUW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_04793</name>
        <name evidence="1" type="ORF">BN903_307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076734.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119941at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043813">
        <property type="entry name" value="DUF5795"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19108">
        <property type="entry name" value="DUF5795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8106" checksum="3B6348290E644EAC" modified="2014-02-19" version="1">MSNRVVQGRMVTPEKLAELVEGESVLEAESIADADRDCPDCGGDVISVGYMPSVTEFVTGYKCQDCDWSDDDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW8</accession>
    <name>V6DUW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transport system permease OppC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_02896</name>
        <name evidence="7" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077460.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63271at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="134"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="349" mass="37985" checksum="E54C781BC7769A6B" modified="2014-02-19" version="1">MTDRQTHDERGRIRISGFDSDRVRDREPMSDWTDESSGETVGRWRRGFRKFKRNRSAMGALVIVVLMSLAAFFARPIEMFGMVVQPFSLAPYDPTTILYLQDPAVEVYDPPSWEYPMGVDGSGRDLFSRILVGGRYSLSIGFIVVGLTGSFGLIYGSISGYYGGNVDELMMRIVDTIFAFPGLILALIIVAILGGGYWQLVLAFSLFGWAGYGRLVRGEVLKIKENEYVMAAKALGARDRSVVFRHIAPNAMPPLIVLASLNIGSVVIGVAALGFLGLGLDPSSAEWGTMLNATRSTLIQGPGGQIPWWATVYPGAAIFIFVMSMNMIGDGINDALDAQQTGVGRGGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW9</accession>
    <name>V6DUW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transducer protein htrI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C464_13985</name>
        <name evidence="8" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="42"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="115"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="187"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="473"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="79"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="503" mass="53685" checksum="7BBA4AA95A43125C" modified="2014-02-19" version="1">MGVGYVTTGGFIVAVGLITNEVNATIVASIAGLLTLGSINAAETVASVTEIGAQTRRVANGDIDSRVESTRTDEFGQLADSIEEMRVSLKDRLTQMEQTQGELEAAQSEATEMADRYRRTAERYGEVMERAATGDLTQRVDVDEDDEALATVGESFNRMMDDLQATVETVTEMADRIETDAGEMAEMSTDVERRVGEAVGTTSTIQSQSEEQREELESIATDVENVSASAEEIAATVDDLSDRSEDVATASSDARNSSRSALDEMAEVESEAEQAVDRVERLREGMDEITEIVDIIGEIAEQTNMLALNASIEAARAGEGGSGSDGFAVVADEVKQLAEETQTRANEIDEMIDEIADQTEEVTVSIRSTQERVQSGTSTVESTLTDIETIAGSVEEINQSLEEIRQTTADQADTVQDTAGSVDSITELSSETADTATGAATEMEESQEVVERISDSLRSFRQDAVTTLQDRVSAFTVESGGPSPSDLDGGTTGGRATTDGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX0</accession>
    <name>V6DUX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rfbB</name>
        <name evidence="3" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077016.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43299at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="4"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="308" mass="33852" checksum="775BD6CFE95B2F8C" modified="2014-02-19" version="1">MRILVTGGAGFIGSNFVHHVLAEHDDDEVVTLDALTYAGSKANLDGVLDDPRHEFVEGDIRDRELVTDLVADVDAVVNFAAESHVDRSIDGAEPFVSTNVQGTQTLLDAANDADIDRFLQISTDEVYGQVLDGKFAEDDRLNPRNPYAATKAGADLLAQSYQTTHDLPVLITRTSNNFGPRQHPEKLIPKFITNAAAGESLPVYGDGSNVREWIYVEDNCRALDLVLRKGEVGEIYNIGSHAEKTNLEVTEAILDAVGADDDLIEFVEDRAGHDQRYALDTAKIEALGWEPAYTFEEGLDRAVQYYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX1</accession>
    <name>V6DUX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6784" checksum="E67C75410CBE8BCE" modified="2014-02-19" version="1">MGPVRSPGDLIDCRREGRTRGTRGERPDPRTSSDGRVVPVIRVDSLAGNTGKVRLVQYGLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX2</accession>
    <name>V6DUX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="1">1.4.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_05680</name>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019651">
        <property type="entry name" value="Glutamate_DH_NAD-spec"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10712">
        <property type="entry name" value="NAD-GH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="273" mass="29745" checksum="A1E87EA13BF01C7F" modified="2014-02-19" version="1">MDRTAVGRGDEGEVDGRLLLVRQLDLRLLGGVLQALERLPVVAEVDPVVVFELVGEVVDERLVPVVAAEVVVPVRGDDLVDAAAEIEDRHVERAAAEIVHEDGLVGLVVEAVRHGRRGRLVDDALDLEAGDLTGVFCRLPLLVVEVRGDGDDRLLDVVAQVLLGVAFDLLEDHRRDLLGRVLLVADLDGVAVLAHVPLDRLDRAVGVLDGLILRRLADEALVVVSERDDRGRRPVALGVRDDLRLVAFHHRERGVGGTEVDTENFVARHLGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX3</accession>
    <name>V6DUX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
            <ecNumber evidence="5">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C469_13695</name>
        <name evidence="5" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="23307" checksum="5A045B1BB22D7D50" modified="2014-02-19" version="1">MESRDGVTCIFGPNGSGKSTLLKTLAGVVPAWEGQVTHRGTDVTHNRPAENVHNGITMLPQDGGIFGDLTVRENLLLGGYTVDDGAVREERFDEVLASFPELEDKLDERGRSLSGGQQMMLSYGRAMMTGAEVYLLDEPSSGLAPSLIDQVFEMTRRLVESGAQVVLIEQNVREALRIADYVYILAQGQLQFEGTPDDLTNEDDLVELYLGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX4</accession>
    <name>V6DUX4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4662" checksum="43B496E20129197A" modified="2014-02-19" version="1">MPKKVHVYPGKTGGFPVFEAERPRQRRGRVSGPDTVRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX5</accession>
    <name>V6DUX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C445_05993</name>
        <name evidence="2" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8638" checksum="C422B76915720A26" modified="2014-02-19" version="1">MENRESDTETLELASGLIEQIEARIGPSEFETVDAYVEYVLEEMLYNMDKSDEKTDQGGPSKEDVEDRLKSLGYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX6</accession>
    <name>V6DUX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_06164</name>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077534.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108535at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14243" checksum="A5B27D498828EBC8" modified="2014-02-19" version="1">MHFDQRTQRALREAGLETDEIAAVSDRVAELVAADAEALTDFFAGDGPVYSDMEMAHSATDIQEHPTADVDLFTHGSDLRGYLSLDGWGVPVEGGRVLREDDNAEPVLVELALGDTVNDRVRFARDREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUX7</accession>
    <name>V6DUX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10364</name>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="17162" checksum="DD7E91E1F5C9DA0E" modified="2014-02-19" version="1">MFVVGLVAVVVAPAVSARDWKVLLPAELLGLALLPTLVRALLGGELGVFATYLAIAALALVIIVEFHMFTSLQVTHWFAVALVTLTTLATAGAWTILRWNADRLLDTAYLTTNEALMIEWIYVTLAGLAAGILFDAYFRRRGRRLRRAIRRVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY0</accession>
    <name>V6DUY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine protein kinase, PrkA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06219</name>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077538.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2180at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="30"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="695" mass="80066" checksum="6B254B1F4DD08BEB" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY1</accession>
    <name>V6DUY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA family ATPase protein</fullName>
            <ecNumber evidence="4">3.6.4.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_10664</name>
        <name evidence="4" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="257" mass="27422" checksum="42E5A4A2BAA37A55" modified="2014-02-19" version="1">MYWPLEYADRFAEMGIDPPSGVLLHGPPGTGKTLLARAAASLSDANFIPVNGPELLDKYVGASEQAVRDLFATARENAPAVVFFDEVDAVSPKRRGDDTGAGERVVSQLLTELDGLEPLTDIVVIAATNRPDNIDEALLRPGRIEKAVETPLPDRDARREILRIHAREMPVASDVDLEAVADRTAGYSGGDLAALVREAGLLAIEDGIVDDGPTTDSTVGRGHFERALSETSPSTRDGRAGVEPSADDRPESDRSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY2</accession>
    <name>V6DUY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10384</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077471.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82461at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007352">
        <property type="entry name" value="DUF420"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37692">
        <property type="entry name" value="PTHR37692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04238">
        <property type="entry name" value="DUF420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="219" mass="23712" checksum="B8D39BDD917C1D57" modified="2014-02-19" version="1">MSTASVRDRAAEHPTAITVLLTIVGYGAVGGVFLVPEFQALFPTLTQGTVDLLAHAIAAVNTVTVLSLSLGWYWIRNDEVKKHAAAMTTSFVLILLFLAMYLPKVAGGGTKEFVLDSTYAWVPLWDWVYPAYLVMLAIHIVLSVVSVPVVLYAIVLGLTHTEQELRTETPHRRVGRIAASAWILSLALGVVTYLLLNHLYDSTFAAAEAATVLLPAVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY3</accession>
    <name>V6DUY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS240-type transposase (ISH102)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_06262</name>
        <name evidence="1" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4331" checksum="9C710746871C5722" modified="2014-02-19" version="1">MTRSLSLMMRLHFTEPVVNTASILDTNDMEIGTASNVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY4</accession>
    <name>V6DUY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C474_20591</name>
        <name evidence="6" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="111"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="35553" checksum="AC1D34DC21C6CA8E" modified="2014-02-19" version="1">MPDRGANVSTRATVVPDPIAAAAARVTDWVEDLSETQFAYLVLAPVLVVFALVALWPVLYSIQTSFFADSFSQFRGEFVGLTNYVELVTGQRDALLLRPFFDLSNPFQSIIPTTLIYTAVSVVLVTALGFVQALILDKTFRGRSVVRTAVLLPWAVPVVIQGMIFYLLFIPESGLGTQAFNGLGLIGTRPLNDSGATLGIVTLAAVWKRSAFVALIVLAGLQSIDERLYDVAKVAGASRWERFRLITLPQVMPVLLIAMLLTSIGSMRVYGQIDAISNCSTMPSITCAVVGTFNGSLYGTASALAIITALLIGLVSMVYLIKYNDSTAGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY5</accession>
    <name>V6DUY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type transport system permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_06029</name>
        <name evidence="7" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK39997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077519.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63271at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="126"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="328" mass="35384" checksum="950F558E111EF607" modified="2014-02-19" version="1">MSINSATSDDDTPDGADESGGPDEVEARVGLRYTLKQVRQDTTARIGTYIVGFMTFVAIFAAFDYYVLDYAIAEAVLYNPETDPENVRRLLPPVGMENQFGQGVLEHPLGTDHRGRDLLARTIYGTRIAMTVGFLATAIGLGGGTVIGAVSGYYGGWIDDVLQRVTETIYAIPFLVLVIAFMTAFGRDLTFAMIGVGITAIPVFNRLIRSRVVSIREEDYVEAARAAGVKDRNIIFRHIIPNSFAPVLVQATLQVGVSILIVAGLSFLGFGAQPPTPSWGQMLSASRGYMLPAPTFSIFPGIAILITVIGFNILGDGLQDALDPRINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY6</accession>
    <name>V6DUY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8858" checksum="79CE175A7A3D03BB" modified="2014-02-19" version="1">MATTALLALGNTHGVRLATDLDGVTVSGVYLRALKRYFRTIGRRGQRARHARNGEEERDEHGHSASLHSSRMGHPVFNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY7</accession>
    <name>V6DUY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C491_18039</name>
        <name evidence="2" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077023.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116612at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="21339" checksum="D261CC88085EDB96" modified="2014-02-19" version="1">MAPAIAHFLLGAAVLLVFASPILLRYEINRIDAVWLIPIGGVWGIAPDFHNIAPVFVDGLYALHGSPWMDLFGIHYTLDRTAIRARYYGSVFSSIAIFIGAVAGYWAISRSETRNAVVNTAIGRGSVVALATAIATPFATVAFGIAVSVQQGFPVAAGLLGSESVLLGGLGVGTVGLAIGPLFAGGRQLPHPKRLRRFEGGACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY8</accession>
    <name>V6DUY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Menaquinol--cytochrome-c reductase (Cytochrome bc complex) cytochrome b/c subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C472_10414</name>
        <name evidence="12" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="11">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK39961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="188" mass="20576" checksum="EC872F25EE2219F4" modified="2014-02-19" version="1">MLGFPTWPHETIRNLAITSFFLGIILLVAAILPSHFGDPANPGSTPAIILPDWYLYWSFGLLKLDPINPDLAVLGGNIVMSNELLGLIAHGAIFGVITLVPFLNKGNARRPVEEPGWAALGVAGVILAITLAALAIQNFFPVQLELLFSLVFMLPVAGGVVTYAVLKTMREGYMYDLNRRYYMLRPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUY9</accession>
    <name>V6DUY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06069</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="5917" checksum="CB2539F3DD053D12" modified="2014-02-19" version="1">MRRGRIGFMNLTAVLHAGFGVSVLAGILVSDTTLRIAAFALGAVLFVAGIAVSRRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV71</accession>
    <name>V6DV71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalamin synthesis protein P47K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11759</name>
        <name evidence="2" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="1">
        <location>
            <begin position="12"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="208" mass="21830" checksum="1ED2E383F28D5A4D" modified="2014-02-19" version="1">MDDPDETDDRIPVTVLSGSLGAGKTTLLNHLLGNAGDRDIAVLVNDMGDVNVDADLIAEGSEVDVEGVTELSNGCICCELQDDLESAVVRLANERSFDNLVVESSGISEPAPVARLFTTESRAAARYRVDALVTVVDTRQFLDAFXXXXXXXRSASRCRTTTTSTSTGSRTGSCTATTSTATWSSTASASSCTRRCASATRSSSSTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV72</accession>
    <name>V6DV72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07505</name>
        <name evidence="1" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077553.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87280at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="201" mass="22646" checksum="F5EE0A22923AD3CD" modified="2014-02-19" version="1">MGIFDTIRAVLGTSAETDATREADPEDLFGMSTAYMTMEADLGYDHCGEAALCFSGVDSTRFDDAVETVEAILEAGEIETGTGFHRHEDDHGYQWFVLEDDDPEDLVTSVHFAADQFIEEGFGSRLLAAVFGFENDDGAAYWIYSFRRGAYYPFAPRGTNDRNQRVEFKLQSVLDGELGLEDDESYWYPLWPDTRGSHPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV73</accession>
    <name>V6DV73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HalDL1DRAFT_3158</name>
        <name evidence="1" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045920">
        <property type="entry name" value="DUF6339"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19866">
        <property type="entry name" value="DUF6339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="263" mass="30371" checksum="D032535E70B96ABC" modified="2014-02-19" version="1">MTTELYHLQSAAHPMIDNRFLAGDRELTKDDLRPYLQPLGRSIDLSPVDERIEEIRADDDIDAQDSLIDAELAPTLHRTLDLTRNEAADAGLWHFLCVVRFPEFVHYRWDHVFDPESPSNMEEKFLKAGTDAYSNALHRIWWGAELTYEEGESGKVEDRDYSRTKQVLGFQELANDILDHDFARYIPVTHACGDLLCHDTLNEIKEEDTYDDPPSNSNIASRTTTLLREELTVRRVEMMEEDDIVETIEDLRDDVMRGEAGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV74</accession>
    <name>V6DV74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, IclR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_16179</name>
        <name evidence="4" type="ORF">BN903_214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077077.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82473at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="IclR-ED" evidence="3">
        <location>
            <begin position="69"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="248" mass="26878" checksum="3B190624CCC5D13B" modified="2014-02-19" version="1">MGDTDTVAVQATATSFRIVEELYDRDGGGVTELADALDVSKSAVHNHLSTLCDLGYVKNVGGTYELTHQFLRIGFGTRERNPVYHAARSEIRMLARNTGAVANLVVPEDAEAVYLHRIGTRDHPVAVGDGVRLHAAAAGKAILASRSRERVDEYVSRHGLDRETDRTVTDPATLRSELRSIRDRNIAFDRGELDENWQCVASPIVVDGDPVGAVSVSGPSDEMQGKRLEEDTAGLVSSAAKTIELELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV76</accession>
    <name>V6DV76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_08500</name>
        <name evidence="7" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077603.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82041at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="373" mass="38218" checksum="41196AFD5AC8387F" modified="2014-02-19" version="1">MGTTDSSIVDSVRARPGLLFVVLLGGLLLVDLAAKLGGVGLGPIGGSVSVDRLGSNLWNGIVIGLVIGLAGIGLSMTYSILSFANFSHGDLVSAGAFTGWGVAFLIAGFGDIPIRALLTVRDAGSVSPGDIGAHILSTPGAILVGLVAAFVVTALLAVALDRAFYKPMRDRDGISLLIASIGAALIVRYLLQFGYGSDRRGVTASVEQSNLAFGPLGVSVNAHELTILVAAVGLMLAMHAMLQHTKLGTAMRAMADNKDLALITGIPAERVVTATWIIGGGLAGASGYLYVLLRGTIQFDFGWLLLLLIFAAVILGGIGSVYGAIVGGLVIGVVFTTSTIWIPSDFNQAAAFAVMILMLLLRPEGLFGGVSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV77</accession>
    <name>V6DV77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">A/G-specific DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Halru_3020</name>
        <name evidence="1" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="80602">
        <property type="entry name" value="V.HspAJ67ORF102P"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="9108" checksum="228797E5EA7C0C1B" modified="2014-02-19" version="1">MGEENRREYPWRESNRTLSEVFVAEFFLTQTPADNVVVVYPRFLERFPTLDTMAKASEDELVEAIEPLDSKIYVQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV78</accession>
    <name>V6DV78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07460</name>
        <name evidence="1" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077557.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="120594at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024064">
        <property type="entry name" value="FdhE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14360" checksum="56C53725C9EE1751" modified="2014-02-19" version="1">MTDRDTPTDRDTPTDRDLPADRAFVCDDCGNRWYYDRRRCPNCGRSSADTATVRLETGTVVATTTVETTPPDVRAPNYLALVRFDEVQLTAQAADGDLSPGDRVRFAGSHRLREGRDRTDPRLVAVDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV79</accession>
    <name>V6DV79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase D Active site motif domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_16647</name>
        <name evidence="2" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="282" mass="31526" checksum="260559B5A7311918" modified="2014-02-19" version="1">MVRQFDALDRVFAIRNAILALNRRDVTRADVDRELETPLTTREAAALFTCLQKNGAATQSEVDERGFASYTFEVDPPEVDRVLTQQAAVIAADSRSSQTDQDDSVEFVATLPGGFEPTSARVHSIPDIASTIRNQVFDADSSVRIANPYFDPSLELVSDLASLPRRGVETQLLTRETTDEEGDTRTTLNKMWNLIDEEHRDNFEVRDLYRWDEGQGSQAFATHAKIVIVDDRICYVGSANLTDTSLTTNFEFGVVVEGDIIKDAVTVFDEVFEYSYPVDLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV80</accession>
    <name>V6DV80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C464_17232</name>
        <name evidence="5" type="ORF">BN903_219</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BAT" evidence="4">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="212" mass="22932" checksum="629B98005271A9D5" modified="2014-02-19" version="1">MLTQLATAADCTLAYDGGVQQTATENYVFVTVDDAPLDTVVDATDGLTVVEDVQRIRGGDSGGVLRLQLSDPFLATELADHGAVLRSATATTAGTTLVVDLPASIEVRHVTQFLADRFGDLELVSKQTREQASEHGFYASVLDRLTDRQLEVLETAYYSGFFESPRKANGEAVANSLDISPQAFYQHVRTSQRKLFAALVDDHTSIPAQHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV81</accession>
    <name>V6DV81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14072</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077600.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117224at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012041">
        <property type="entry name" value="Znf_CPxCG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42195">
        <property type="entry name" value="PTHR42195"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19769">
        <property type="entry name" value="CPxCG_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015877">
        <property type="entry name" value="UCP015877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="24115" checksum="8D84469FC040CEE9" modified="2014-02-19" version="1">MSDIESGDRVGLPCPSCSPSEPTVHEVLRPGGQATVRCTECDHTHKTEIPEEETVSVTIVVSQDGDSFTTRMDVPADGDVAAGEEFVVDTDDALMQVRITDIELGPEERVEEAAVTDVETLWTRAVDNVAVPVTLHPKDGDADQTRSLRVNVPGDYEFVVDETVEFGEEQFTVEGLQIREDAPEYRHEKLDHPGDLAYAKDLKRVYARDESLTAWSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV82</accession>
    <name>V6DV82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Natpe_4318</name>
        <name evidence="7" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7585" checksum="840BE479028C9E95" modified="2014-02-19" version="1">MPVVLPKDAESDWLAADPNTRKELCQPYPKDDLDAYEISTRVNNPGNDDPQVIELLDHEQSGLGEFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV83</accession>
    <name>V6DV83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6334" checksum="2FAF7EC9A7CBB969" modified="2014-02-19" version="1">MPVSDVLRDAVNATVVFPTTLENRCEMNLNYTENVPGTLPRIQPETHGVYLTPYQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV85</accession>
    <name>V6DV85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4891" checksum="EAA2DC2FACD13ABA" modified="2014-02-19" version="1">MLIQLFQHPDHYYHYNRPSQVRWYNSQRTDSRFMTRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV86</accession>
    <name>V6DV86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_00069</name>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9577" checksum="338B103E3C9EB8C9" modified="2014-02-19" version="1">MYHLRADVPRRLQGDALGVSRLRREQVPVQARRRDGGPDASETPVADLRETYETAKRGYETILEKYAEEEGQDATEDETAGNDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV88</accession>
    <name>V6DV88_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C498_10916</name>
        <name evidence="2" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12820" checksum="5755D92FAC0B2330" modified="2014-02-19" version="1">MGRKNPTYRDALRAIEERWAEFRRALRRRDQPRFDQLFEYAREHADASGLLNHQNPLLPALLSIDLEQEARLVLRDAARSSRRKPAVTTRLGSDGDSPGARGNSGSERDCLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV89</accession>
    <name>V6DV89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_17472</name>
        <name evidence="2" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="15923" checksum="5E1E4228CCB936E7" modified="2014-02-19" version="1">MSDGDESSQRGKRTPTERMDRYVSSSGETPEAEETSKTGEASETLEASETSETEEIVDQNGTFEPRLQWVGGTSVRDRANLNFYLPDEIKAKIEATYLQLNIEYQQQYGEKLKKHEQYYPHLLEQGLNEDDLREQLGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV90</accession>
    <name>V6DV90_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VRR-NUC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077608.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="135961at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="4">
        <location>
            <begin position="95"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="19031" checksum="B411FE6249251111" modified="2014-02-19" version="1">MKITTRYTIQDWQTQEIEFHEIPEPVMELSFKQVLEIALVELGSVDLNPIELTFSCIFSHEEWNVIRTPMNRDTPVQQYISVAIERATGVREALYGSGVPDFFLWTPEGEHKFVEVKASEDSLNSNQKEWADNYDWNFAIAQLAPASERMSDEDILERNKIALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV91</accession>
    <name>V6DV91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_11845</name>
        <name evidence="1" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077569.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77157at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="21435" checksum="17D58FE0018BC201" modified="2014-02-19" version="1">MDYSLAVENGPETIPGGTGLLLVHPSIGETDRIDTDFLKTDTDAFLVVSTRTTAREVEQKLEYYDVDETKATILDTLSVERGYSRRTSDDVYYVSAPDDLDGVVDRVERFLTENEGKRRVSVDSLTEMAYYADDDAVYEAAAEILDLLDEHDAVGIFHLSEEVHEVATLDRFRELFDGVIDLDGDGNVVVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV92</accession>
    <name>V6DV92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7273" checksum="FF5067E17EF53362" modified="2014-02-19" version="1">MKIVCILKRWKEEISLLFLCVGWILLGVINGGLSIPNTPYEVSLLVMFLLTFGILVHKVRQSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV93</accession>
    <name>V6DV93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="11921" checksum="EADA2DC9190F9D7B" modified="2014-02-19" version="1">MDAFDCSAMRMNSLRKSMTLAHQKTSERYEGQMDRRTIIKSIYYLIYQKNIINSVPSYPQIDTWIPTDRIRNAQQTRRVVYFLIGCFPLGVTRNALTVRVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV94</accession>
    <name>V6DV94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077118.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="7931" checksum="A53DD290CEC9E623" modified="2014-02-19" version="1">MDTSHIHSEVIPEIVESYDGELNQDGDVPVRAVRTILVDEHGLTEQEAYDVTNVSGPNGIDIEVTNTGGVVLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV95</accession>
    <name>V6DV95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_08490</name>
        <name evidence="8" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077601.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="42569at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="57"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="89"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="308" mass="33063" checksum="96F55B6C3F0B3B93" modified="2014-02-19" version="1">MSSDAPDADEVAGSVDVADAEEVAGSVDAAAAVDEPEANDSEVEEAAKHVPSGSPPLRVEGLVKRFGGVTAVDGASFEVESGSLTGLIGPNGAGKSTTFNCITGVHEPTAGTVYFEGEDVTGLKPYQIARKGLVRTFQIARELSEMTVLENLMLAPQGQLGESAIRAVTPGLRSAVVGEETEIRERAWETLEFFEIDHLAHEHAGNLSGGQRKLLEMARVLMTDPEMVLLDEPLAGVNPTLEEKLLDRIHQLRADGYTFLLVEHDMDVIMNNCERVIVMHQGSVLAEGTGDEIRNDERVIEAYLGEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV97</accession>
    <name>V6DV97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_06342</name>
        <name evidence="1" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076871.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105806at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="13065" checksum="F25095FAA44162F7" modified="2014-02-19" version="1">MSQQQRAENVSIDDIPVDIAITQSDTVEPDDVPEEIESITRGLASEHPPTNPLVVLKAARWWYIHGKGGTDPAFQWAIEWARHLATDTPSDVERFDEFLKYLVTVGFADEHHELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV98</accession>
    <name>V6DV98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3507</name>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="7099" checksum="65B13B6ABE336FD0" modified="2014-02-19" version="1">MGTELYTIATMPETKKTTVVQDSDGYYRLRVPKALGDAMDLSDKKVEWSVESSKKLSITKIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV99</accession>
    <name>V6DV99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5474" checksum="F5A4FE09DD841632" modified="2014-02-19" version="1">MKERVEGGDEEYREYLKEEYPYLYWSWEWTGDPPEEVTRELGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZA0</accession>
    <name>V6DZA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="150" mass="16006" checksum="9A39FC09872C0A54" modified="2014-02-19" version="1">MSIARSGVGWAIAKLGTLGLSFASVVLFTRVMENPARTLGTFQVFEMIGTFGVLVAGIGLSPALVKRGRQGTQGIGXXXXXXXALYSSFHHLSLCLSYCISAGTMSRLSSGLNRPLCWQPSLSFGYFRAGTSLFQRSRAYLVSVGQVPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZA3</accession>
    <name>V6DZA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="5902" checksum="39EAC078D3F40A57" modified="2014-02-19" version="1">MTDVGLADLLAVPFAVVRFDVAAALLFAAVLVSGGDVRPRTLLVLVSPSLTNSFVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZA6</accession>
    <name>V6DZA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6076" checksum="59436AB906B06881" modified="2014-02-19" version="1">MLSQSLIPIYKTLLIHMKLRNQFTPTNHLSVDAHRSRRISCSRRATVAPLFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZB1</accession>
    <name>V6DZB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferases group 1 family protein</fullName>
            <ecNumber evidence="3">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kuste2609</name>
        <name evidence="3" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.57" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="198"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="385" mass="43260" checksum="D5A60F44A2436637" modified="2014-02-19" version="1">MDQVVGLLRRGHDVHVFALEDPSEEFHHEKVDEFDLTRRTTYLGRPANAIEGTLTAGRLALHHPETLPEIVRSLERGVEGGGRIAALYQFRSHIRSDWKFDIWHAHFGPIGKRWDFLPTLEDKPYVASFYGHDAASNVPENRSTYTYLFDHADRITVLSEDMRDDLVSNGCPRDQTALQPLPVDTERFSPAPEKSWRVGPTEVVTVARFVEKKGLDDALEAIDAVSAEHDIRWRIAGDGLLRDKFESEVAKRDLTDVVKTLGLVSQTEIQRLLAEAHVFLLPSKRASSGDKEGTPTVLLEAQAAGVPVISTEHAGIPEIVRDRESGVLVPEGDPEALIQALEKFLSNPDRWEEMGQAGRELVREKHSLQAVARRLEEHYRAVINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZB7</accession>
    <name>V6DZB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_1494</name>
        <name evidence="1" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="11168" checksum="216AEE7CA7750F05" modified="2014-02-19" version="1">MVDEKMFRLHGQKFWLYGAVGPYTNEIRQVSLYPTATKQTTRWFLIELHRRYQLDDVEFLVDDADYLGPILAEDGYRFRVIRHGNRNAIERVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ0</accession>
    <name>V6DQJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_06342</name>
        <name evidence="7" type="ORF">BN903_164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076300.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108290at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="16594" checksum="6EEC7CD48760846F" modified="2014-02-19" version="1">MTDDETDSDPEADSDDPDRSLAPLMGATYVAAGIAHFLAPKRFAAAIPPSFPRPVGLVYLSGIAEVVLGAGVALRRTRRPSAWGIVALLVAVFPANVHLARSDVLNDLVPERFADIARLAAWVRLPFQAVLIGWALRYARSEETSMSEAEPDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ1</accession>
    <name>V6DQJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06392</name>
        <name evidence="2" type="ORF">BN903_157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076293.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117135at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="10977" checksum="4B5668CF9A24CB7A" modified="2014-02-19" version="1">MDRQRLERALEDEFGGTEAERRAVSRAARDLVDSGRPSEDRGHGLTVSGAVGHMEDAPDGSSLVERWNWWMGALDAAYGGYDYFTVRFVDGDEAAGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ3</accession>
    <name>V6DQJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="12217" checksum="2B2AA74E6FBDB72B" modified="2014-02-19" version="1">MTTTSKSSGLSVGLRPRADHAERGRLGCEFTDCERAETVRAGVRDGRAGHVRLRAAGPGVGISNVEITRYHGICYMGPYLASFYQYCMIKTGILIMSRESGFFTIHLQRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ4</accession>
    <name>V6DQJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeS assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="3" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075778.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19042at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="476" mass="53309" checksum="C8EB04116FBC2103" modified="2014-02-19" version="1">MSSKQDDLKETNTEARFEFKKEEKSAFKSDKGLTEETVRVISEDKDEPEWMLERRLRALEQFQEMPMPTDWPGQPDLSEIDVDEIVPYIRPDVDVRAGVDDWTELPDEIQDTFDKLGIPEAEKNALSGVGAQYESEVVYQNMQERWEEKGVVFCNMDEAVQEHKELVREHFMTKCVPPSDNKFAALHGAIWSGGSFVYVPENTTVDMPIQAYFRMNSEGMGQFEHTLIIAEEGAEVHYIEGCSAPKYSKFNLHCGGVEVFVDEDAHVQYSTVQNWSKNTYNLNTKRAIAEKGGRMEWISGSMGSKATMLYPSTILKGRGASDNHITIAMAGEGQDIDTGAKVYHNAPETKSTVESKSIAKDGGRTNYRGLVHIADGAENSSTAVECDALMFDNESTSDTMPYMEISESKVDVAHEATVGKIGDEDIFYLQSRGLDDDDAKQMIVSGFIEPITDELPIEYAVELNRLVELEMEGSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ5</accession>
    <name>V6DQJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01062</name>
        <name evidence="2" type="ORF">BN903_169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="10086" checksum="71FEAD91D663E7F2" modified="2014-02-19" version="1">MEPHSPSPGRKPISTPNRSADVYLGLALLLLAVGIPHAIWPYEFARFEERIDSIGSKRSWSEVEPAEWKVDLTRVVGIGMVFLGLIELLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ8</accession>
    <name>V6DQJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase ISH18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_14465</name>
        <name evidence="3" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075781.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40179at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="3"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="332" mass="37281" checksum="C33096F3BCADF747" modified="2014-02-19" version="1">MYLGIDVHKRYAQVAVMDEAGKIVEEVRVENANLDELAQRYAGAQAVLEATSNYYHIHDTLSEHLDVTVAHPKKINQIADTDKKTDRVDAKELARMLRLNSVPESYVPTEEVREARALVRGRQTLVENRTKYANKIHGLLSDHGITEDVKPLNVKGRESLRELSLPVPWDTLLESYLDLIESLTEEIQKLDETIEERAGSLKKTQLLMTIPGVSYYTALTIYAELGGIDRFDGDKEVVSYVGLNPVIRESGDSRIEGSISKRGSGRVRWLLVQAANTAVHTSNDEYLSQFYDRLASRKNSQKAIVAAARKMLVSIYHMLDRGEVYDPPGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQJ9</accession>
    <name>V6DQJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="12294" checksum="758EDC632A69A8BC" modified="2014-02-19" version="1">MRVEFHVVGLALAVGIVHRDGDGLARVAVAEDRGERLVVDDALAVDRDDRQRLAEGRPLVVDRAALLNADDVRADRYVRDGDGGLTVRGLDGRGVLGPGGVADRVEDARRCRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK0</accession>
    <name>V6DQK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4838" checksum="717F721BECBA28E1" modified="2014-02-19" version="1">MLYSRSYRPDTQKDSHSIPLTKQYCLRKENQKSLIKPHMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK1</accession>
    <name>V6DQK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spermidine/putrescine ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_00229</name>
        <name evidence="1" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="362" mass="39574" checksum="02FA45DBF3A3C94D" modified="2014-02-19" version="1">MEDRRQFIKAAGAAGVTGIAGLSGCMGGSSGTTVSILTWTGYDAVNDQIEETLDGVELEISIADGSANMFSTVNAGGGEQYDIVIPNNEYVPRFIDADLAAPVDMDIMTNFDALYPTFQDAAETQFASDGDVYGLPVQFGWYAYGYDSSVLPEDHEHSYDVLFSEEYEGVDLTGGITLYDGYYKTIMATGLSLGYTEAFEGDTVSFTDEQLTTIEETLTDFKPNLLGFVHDEETLTQDYQNGNIVASFANRSTHVGIMNDVESVRFSQPAEEELTWFEGAIVTAGSSNKEASFRVLNEYISPETGAALSENRNIMNTSQDAMGNIDSETLQIEPGVLDGMIPFKPAEQDEEWIEMFERIKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK3</accession>
    <name>V6DQK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7667" checksum="E1A6FD7CC06A3207" modified="2014-02-19" version="1">MLCTDVVRKELFPDLEYTPEDVRTVHNELLGRTADGLMRPTGECGPNRRILMCTHSGQNSSTDTNLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK7</accession>
    <name>V6DQK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9172" checksum="690C54E3C4E2D4C6" modified="2014-02-19" version="1">MTTPTEASNVNRISNEAILLVESTFTLDNRPRVTHPPPDETSRNSSARRARSPLPAGVRTLCRTCVSFRCDPHSRYVLDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK8</accession>
    <name>V6DQK8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4865" checksum="8080179B9BA1C66B" modified="2014-02-19" version="1">MNYRNHGGSGLSRGVNRTAERATTRETISGRSLSSFRSLLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK9</accession>
    <name>V6DQK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_08810</name>
        <name evidence="1" type="ORF">BN903_172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076306.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100378at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032836">
        <property type="entry name" value="DsrE2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13686">
        <property type="entry name" value="DrsE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20405" checksum="16E53EA1CECBB699" modified="2014-02-19" version="1">MSTDTPDASADDAPSRAELAARVDELEDALAEATSDDDGKKMSIIATKGTLDMAYPPLILASTAAAFGYEVTVFHTFWGLEILHEERSKNLKLSSVGNPNMPVPNAVAALPGMDRVTTKMMEKKIADNDTATIEELIETSLDMGVEFQACQMTIDLMDYDESEFYDGVTTGVGAATALQDMADADIQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL0</accession>
    <name>V6DQL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.119</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_14368</name>
        <name evidence="2" type="ORF">BN903_184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076314.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88190at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="14080" checksum="F657808D74E61011" modified="2014-02-19" version="1">MPVATVGETATHAVSITDEAIETFAALSGDENPIHVDDEYAAETMFGGRVAHGILSVAVVSGALARLSGDIVYLSQDLSFENPVFPGETVEATVRVTDDLGGDRLAVETTATVPERDERVLSGEATVLSVPHGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL2</accession>
    <name>V6DQL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4745" checksum="E6E245CF42F48D3C" modified="2014-02-19" version="1">MVLVESIERHELTVRVLTSSTEPLLEIKVFVPEFDVSSGTEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL3</accession>
    <name>V6DQL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01402</name>
        <name evidence="2" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076262.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51226at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="7"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="313" mass="32380" checksum="10B959F6F87CA987" modified="2014-02-19" version="1">MSDNQRGVLVVGDTTIDLYPVDGTSITPGSRFAWHVGGTATNVARWAASLGSETSLVTNIGTDVMGELAAQHLADGPVDATHVTRVDAPSPLTLYVPTEAGDRWNAWVAGSCYGFTPPADPASLVVPYEWVHLEGVTLPTEVNQSAVRRLAEAAAEHGAHVSFDLNGRTNQWATPDAYQQALRDVLRHCDLIFAGTDDLAVADVDRTPAGVLELLPPNHSATVFITDGPGETTAVTVEDGEITERVTATPPPATVATTAGAGDAFAGAVLAARDDGVSDLRELATIGNTAGAAAVATIGPFDADGSDLTGELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL4</accession>
    <name>V6DQL4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulf_transp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_14559</name>
        <name evidence="8" type="ORF">BN903_177</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076469.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103517at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="7">
        <location>
            <begin position="50"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="16257" checksum="9DEF66EF8E90981A" modified="2014-02-19" version="1">MSEDRHPLFKPLIFIGGLIFGFGLGFSHMARPEVVLNFLQFDDLGLPFVMFGAAIVSGVAFALLPRIRDAAPLTGNPYERRLKPFDRNVLVGGAIFGVGWGLSGICPGAAYASLGVGNVTILWALAGMFLGAYAQGYWRSHGQARDTAPAGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL5</accession>
    <name>V6DQL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
            <ecNumber evidence="6">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C473_14202</name>
        <name evidence="6" type="ORF">BN903_189</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076317.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58905at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="3"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="255"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="291" mass="30959" checksum="3490EDFCF1589CC6" modified="2014-02-19" version="1">MLLETEGLTKRFGGITAVDGVDFALEAGELCSIIGPNGAGKTTFFNLLTGVLEPSDGRIRFDPPDRADSDASVDITAASPDETALAGIHRSYQITNLFPTLSVLENVRVAAQASRGNDSWKLWRNVTEFEDHYAEATRILERIGLAGDAETVTENLSHGEKRSLEIGVALAGDPDLLLLDEPTAGVSSEGVEEVVALIEDVAADHSVMLIEHNMEVVMDISDRIAVLHRGELIADGPPEDVRGDEVVQEAYLGGYGREGSEDGFAESETATDDGDAAADGGRRVRAGGEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL6</accession>
    <name>V6DQL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C461_08694</name>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="156"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="286" mass="31568" checksum="ABA8451F2773377C" modified="2014-02-19" version="1">MSSVTAKSAVLATDLSTASQTMIESETGLRCLSQIGVKQIHLVTVVPSSVHSGMPGINFEKRRKRALGRYQSQIEDAGFGAETHVVRGTPHRRINGIASTVGADLILIGSRGESPLENRVIGSTARNLARTAVVPLLVDRIERGTDTPGTVRRHLFKRTLFATDFSENAEHAFNTFEYLRHATEEVTLVHVRSPKDDTGDHAEVESRMQPLVERLGEWELDAKTDIRRGDPTKEILRAEREHEPSTILLGSRGRSRLRRLLIGDVSEDIVAKASGNVFLVPQQRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL8</accession>
    <name>V6DQL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="4794" checksum="32E3F3E15D2F8C36" modified="2014-02-19" version="1">MTTTPANPSATPSAVAAVNSSSVATSRVSAGVTTGTSPNSTAATPPVTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQL9</accession>
    <name>V6DQL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4595" checksum="3AB48EB9B24D299D" modified="2014-02-19" version="1">MTNYSQTGFSHIPGKNVVFGILHYEVLLQLPQYCLVEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM0</accession>
    <name>V6DQM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5235" checksum="31654D35423BE66C" modified="2014-02-19" version="1">MDRMRSSYCSLALTRFATKLYNLYKNLLTPADLRRIDYNARFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM1</accession>
    <name>V6DQM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">XRE family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_12539</name>
        <name evidence="1" type="ORF">BN903_194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4647" checksum="1F0756E2790081E6" modified="2014-02-19" version="1">MAAELEVDEDDLLAVEDGRAATANVGGSVVRALEERFGIDVVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM3</accession>
    <name>V6DQM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage integrase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_16632</name>
        <name evidence="1" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="10751" checksum="6036FC3F8518D89B" modified="2014-02-19" version="1">MYQKRTAAIVKGSSLFFHARHYQDKQHDLAATQAQLRHESVKTTLKYDNVSGRIAVSRRHPRNQFRSDVLHQIVKRWCRFRCRLRTDIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM4</accession>
    <name>V6DQM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XerC/D-like integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C483_17338</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8464" checksum="23EBB7DEC6711931" modified="2014-02-19" version="1">MRVTASQLYSDLHELCEIAGIPVENRQMSWYTIRHSVGTYLTWEKDLASAKAQLRHKSPKTTIRYGQTPVEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM6</accession>
    <name>V6DQM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_3626</name>
        <name evidence="2" type="ORF">BN903_199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="310" mass="34344" checksum="6EC9821B53A719A5" modified="2014-02-19" version="1">MDLTSLVPDSGPNYKLYYLIPASFIYLFYQLGREILLVPALIGLIGVISRHSTSESLYGPDGKKEANLSSQREIHRVGALVYRNKVPAKYSADSWLEMAQEGTFQSTYWAIVMGVIFVFQFSVSVLYIIAVYLLFTNLLVIDYIGGVLLFALVGLVVHGAIRLILPDISDIDDIPSIDQELRTVVEGFSHTLNGDDIVVTGAAYGAARGGIFEIAIEAECESDELKRRTINQIATAFCSVVNRSSYPVVRSDFRIEGKNGSAVYFCIDTKWCRKLSNGQISANEFLHHIGQTVSVREPNGEIVVYPINQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM8</accession>
    <name>V6DQM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GtrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_01464</name>
        <name evidence="8" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076274.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88809at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="20"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="140" mass="15644" checksum="E2BCFEFE63BDCC47" modified="2014-02-19" version="1">MIRATLRSFASGPLAVQMRRFIVVGAFTAGIQMCLLWLFDSVAGLNYLLAATIAIEITILLSYVFNNAWTFRARQNTGVSEYFRGMLKTNLVRGTAWPIQIGVLYALVEWGGMVALVANVPAILISGLYRFVLDYQWTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQM9</accession>
    <name>V6DQM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C463_11407</name>
        <name evidence="7" type="ORF">BN903_187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076316.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="394" mass="41802" checksum="C79967E1B06F4208" modified="2014-02-19" version="1">MIVGFLLYPLVYEALLATPAAPFAETFLPAITFMVVVLYMGLFAMSFDFVSGYTGYLSFGHAAFFGTGGYFVVLAANGQVPGVPGGTPFMITLLLGAVLAGVLALVIGSVSFRLTGVYFAMITLGFAQVIYELIRSWGYVSTNPTEGATVSGDALAIGVPYVDRLSLDVGRLTGESVENLLGLGIDLSATVVSYYALGIVVVVCYFAMQRIVHSPFGRVMIAIRENEERARAVGYATYRFKLAAFAISGFFGAIAGGIFAAYSRSVAPDSTFYFLVTADALITTIVGGFGTLAGPVYGTLFNQGLEDVLSTESGGIATLLREGLPAGVLEAELFGVSVELFVNTAVDGRAPLYLGIVFVLFVLFVPNGILGTLRDRLGGTVGKRLPDHLRRYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR00</accession>
    <name>V6DR00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6473" checksum="51048E3851CDABC7" modified="2014-02-19" version="1">MVERFHLPNVKRAVSLFDGPAAPDRAVSESNPEAPSGAEPNVLPRASPSIEHGRRSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR0</accession>
    <name>V6DUR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Huta_2352</name>
        <name evidence="3" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334930.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="391" mass="44169" checksum="300CA62BDFBBC805" modified="2014-02-19" version="1">MTDQASDRRTTDETRRVLILVADEGNRRVLESWVNGHNRYTLAEATDIAEAAFDCCLFDTRQLGEKRSELLKRKESEEIILPYLLLVPEPRHREIHDRLRDEHPELWDAIDGVIDMPLTEHRLGEQLETFFRLRNQSRSAYTQREELRRVRDQLDVLNRVLRHDIRNDMNVVVAWGEMLEDEVTPAGREKLDRILRAGRHVVELTNVARDLSALTHGDETPDRKPVSLRQILTAELEKRRATFSDAEITMPEPPDPGTHVLANELLSSVFRNLVNNAVQHNRTAHPKVMITVEDDAESVRVSVADNGPGIPDDVKADLFGAGEKGLESGGTGMGLFLVDSLVEGYGGDVWIEDRAESESFGGLDEADQTGAVFVVELPTTQRSDNREESSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR1</accession>
    <name>V6DUR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="182" mass="20753" checksum="D1DFC1407F312A53" modified="2014-02-19" version="1">MEAEHDRPEDVREHEQADVGRLAAEVRPEDDVGDGVDDHDSDREEAGDVREQRHLAVDHDRDRHRRRQRDVDDLHPDHGDEAGDARDRTGQRRVRDLDRGGRDRVVSEVGDDRDDRDGDDVEQVPVQHRFKLFVGGFEVLADDRVVVEPEQPVVEPGAVDEQVVRDDDGDEEVQGEPGQRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR2</accession>
    <name>V6DUR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor IF-2 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C464_08720</name>
        <name evidence="6" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077411.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73843at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="PTHR23001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="SSF100966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="SSF75689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="5">
        <location>
            <begin position="145"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="22373" checksum="594AEFB929FBA2D1" modified="2014-02-19" version="1">MDYESSLDRAMEEVPDLGGSDERLSVPDPEAQKDGAFTRLTNLSGIADALSRDPEHVHSKIQQELGTAGQYEDGRARYSGNFRERDFQAAIDSYIESYVTCSECGLPDTRLETENRTPMLRCEACGAFRPVAKQNTQNTQRQEDAVESGNTYELEIVGTGRKGDGVAERGEYTIFVPGAQEGETVTAYIKNVSGNLAFARRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR3</accession>
    <name>V6DUR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">XRE family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_04478</name>
        <name evidence="4" type="ORF">BN903_252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076693.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102704at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017158">
        <property type="entry name" value="Tscrpt-reg_CBS-contain_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037253">
        <property type="entry name" value="HTH_CBS_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="70"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="179" mass="18927" checksum="0E307ABD0E694261" modified="2014-02-19" version="1">MELPTPQDLRERRTALELTQSELADAADVSQPLIARIEGGDVDPRLSTLRRIVNALQEAEGEVVRASDLMNETVISVAPDDAVSGAVELMEAEAYSQLPVLQNGVPVGSISQGDVVHAGENVGDHPVSEVMSESFPTVAPSATVDEVRNLLDHYKAVMVTDGGETVGIITEADIAAQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR4</accession>
    <name>V6DUR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10409</name>
        <name evidence="3" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077475.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124921at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="15206" checksum="38C764929D9B42EB" modified="2014-02-19" version="1">MSSASDDDSSQAFDETGDPIARDDDADPRNEPTGPQQGPSGREVVVPFRLYKAVTVFSTLAAVVTYFVGFTLIDAATLQISFIRTTIVYLLDNAGILPPEDVLVAILAITGVGFIVLGTAVYVLGTRFRGQGMGKSQDDSNET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR5</accession>
    <name>V6DUR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14472</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_domain" evidence="1">
        <location>
            <begin position="2"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="29946" checksum="E22C08A9A37F56A8" modified="2014-02-19" version="1">MSFNLTRDGSGGGFENVFIPGDSDLNNSSRPIQDEEIQRCRDNDIEPVEFFVAQDALTVVVNNEADFIDEISLEDLRTIWSPDTAPELWSDVNPDWPDEPFDLYGPASTSGTYDYFIEAVIGETEADQDIREDFEGTEEDDLIAQGVQGNQYAFGYLPFAYYTNNPDSVKALSLSEGGSDPVEPSLEGAQSGNYPLARPLFFYGHMGKIQEKNHLQEFLEYYINEAAEDYIAQDIGYVPSSQDMVDANLENLEAAIAGEYEFEPISTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR6</accession>
    <name>V6DUR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_10194</name>
        <name evidence="7" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077452.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105011at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010545">
        <property type="entry name" value="SPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06550">
        <property type="entry name" value="SPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="337" mass="34587" checksum="B05F943B404547A4" modified="2014-02-19" version="1">MFPREYRGVAFVVGLFLAVQLGALALVPEFVDSGYQAVENPDNPANSLLYVVAIVAMTGLMLAAFRYDLDGTIRLLIVGVSAYLSWYVFSALVSPLAAAVPALAVGAGLLVHPEWYVIDTAGVLMGAGAAGLFGISFGLLPALLLLAVLAVYDAISVYGTEHMLSLAEGIMDLNIPVVLVIPLSLSYSLLDGETASEEAAGVGEEDADSEPASDSDAEPASDEDVDTEAPEPAEPGDRDAFFIGLGDAVIPTVLIASAATFSSAPNLSVPLIGVNLPALLAMVGTLAGLLVLMRWVIQGRPHAGLPLLNGGAIGGYLVGSVIAGVPLIEALGLATFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR7</accession>
    <name>V6DUR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetolactate synthase, small subunit</fullName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ilvN</name>
        <name evidence="8" type="ORF">BN903_257</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076697.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="85263at2157"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="49"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="23131" checksum="8371C85674026805" modified="2014-02-19" version="1">MSGDASDSRPLPGEQPGPAERDHPEGRRNLEGIRIDPVVEAEHESRRAVISALVEDEPGVLARVSGLVSRRQFNIESLTVGPTTVEGHSRITMVVEETDPGIDQIEKQMAKLKPVISVGEVAGDAVTSELVLLKVEADDPAAVHAVSDMYDGETVDAGPETITVELTGDKADIDSAIGAFERFGIVEVARTGPTALARGNTPTAPGEKPGTAGEPTTHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR8</accession>
    <name>V6DUR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Blue (Type 1) copper domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_11436</name>
        <name evidence="2" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7467" checksum="220A8BA7BCFD160F" modified="2014-02-19" version="1">MHGGIAVGEDVATVEVGGANTGWPEDIAYVGVPLHAHWVGISAILGIGLTFVFTFYMLKYGESAHTGHGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUR9</accession>
    <name>V6DUR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8998" checksum="11D3E16F6E9D49C6" modified="2014-02-19" version="1">MRRRARGGPHRTSRLPSLAVRALRALTALSRGALVGGFAAGCQRDLRSLPTRAVKRALGGARHRLLVVATMKRLNSMPRNSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS2</accession>
    <name>V6DUS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6593" checksum="84EA169DE8E28735" modified="2014-02-19" version="1">MRSGIHRRAGRWLAAREPRVARRPNETNVDLPYQLASESEYARRPRCVYYLLKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS3</accession>
    <name>V6DUS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="264" mass="28656" checksum="96B5F0761304A212" modified="2014-02-19" version="1">MVRVLLDDERPPPRPAVDLLVRPHPVAVPLQPFADEVVRGGLDVAHRDEVVVEVVALRLLCARVLLADPEPDRPPQKRHAVRGPAQLAHLVRLRGGPADVLPGHGHPADVHHEVRVGHVGVFRPVVSELVDGVVGDPRLGDAGVDERARRVPGVRREVRRNAEVGRLVDVAVDDSDGEVGRVGREGAAAGRRGIGHVTRGRRPRREKRAEGRRGNETTEKQTRPPTDLLASSACENICPSATKASSRPAERRFSRTRSSACSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS4</accession>
    <name>V6DUS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4981" checksum="335DA5784EDD23B9" modified="2014-02-19" version="1">MPPNTGVRDRSPRQKVRRSSKTGPTRGDDREESGEYTSNYIWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS5</accession>
    <name>V6DUS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4140" checksum="AD8BD5D225DDA8D8" modified="2014-02-19" version="1">MPATGVDRGGLAEKRSSADRVETAFGRRFSGKRGWLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT0</accession>
    <name>V6DUT0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="230" mass="25489" checksum="A0A36D79289A79E0" modified="2014-02-19" version="1">MTAFERGHELRRRAEPGDPVVVDVGVAVDRRERELLHLERVHLPVQQVVREEEAPRDREQRHPLAVPHLLGELEAVRPGRDDDRLGVEVAVVGLDEEPVPALVDVRHGRAEVNGDALLRAGGVDERLRDRAVVDHVAVGRLERLQLRAGVAPLDDLRLQLFDLLAADLAELREQVAEPVLAVALLQLGDLLVADAEDHLAPLAVHLAVGVFPFEVAREQLRALLDLLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT1</accession>
    <name>V6DUT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C464_07355</name>
        <name evidence="7" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077461.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="99"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="318" mass="34942" checksum="8E5245FB5BA6472E" modified="2014-02-19" version="1">MSLQRFILKRTLSIIPIMFGVSVITFGLFHLTPGDPVTQLVALNPDVSPAEEAALRERWGLSGPVWEQYLNWISNVLVGDFGQELQTGREVSEIVWARLPETIALGLFGWAFALVIAIPAGIYAAVNKDNLGDTVSRFLALSGISIPNFWLGLMLILIFSLYLGLFPVLPPSRQSLLSPEMLWYLILPGLTIGTASAASIMRVMRTSMTEELNKEYVTAARAKGLPERTVILKHVLRNSLISVVTLAATLTASIVAGSVVVEVVFNWPGLGREFIDAINQREINVVMAITLFTGFFVILANLVADIVYAALDPRIRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT2</accession>
    <name>V6DUT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_13222</name>
        <name evidence="1" type="ORF">BN903_272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6448" checksum="67DA4C7874E3FF26" modified="2014-02-19" version="1">MPAVRTVAFLTGLDGDPADLGLVSVNGEVRFGSEPFLRAVPEGSRLAESLRGVDDDLVEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT3</accession>
    <name>V6DUT3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Maltodextrin-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_10499</name>
        <name evidence="7" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015144">
        <property type="term" value="F:carbohydrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006060">
        <property type="entry name" value="Maltose/Cyclodextrin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00181">
        <property type="entry name" value="MALTOSEBP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="422" mass="45134" checksum="31C39909D46E82DF" modified="2014-02-19" version="1">MNEKRRTLLKAMGGSTALAGLAGCISTGGDGGDGSDGGDGGDSGEGGSGGSARLWTDLADSEDEAMSEYVSQYESETGNNINKEAPGGELDQQLETAIPAGDGPDSWIWAHDWVGRFAVREDPPFLYDASDDVDVSLDGYTQAAREAAQFDGGLYGLPFASETVALFYNEDIVDEPPETMEEMVSIMDEHHDPDNGQYGLSFPATDPYQASGFIQVYGGDIFDESNLEVGLDSDACKQGMDALETLYGYTPADPGYESQIVAFADGLAPFAINGPWILGDFQNDVDNLGVTTLPTIDGNHPRSYSGIQLFYFSSMLADADPSTVDVATDLAEWYTTNEDIILTNADERGYIPVLTDVVGNEDLSAEVQAFAEQVDYGVPMPSHPDMDSVWNPLTEALERVFNGEQESAAALDQAASEIREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT4</accession>
    <name>V6DUT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="8504" checksum="6F0BCD548987ECAF" modified="2014-02-19" version="1">MRRGVVRAEAVAAAAVDLPADELSFPGVGVRAVEDDPVGLLYVGDVDGGLADRELSPVGRLPAALGIEHRLVQHDVVPLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT5</accession>
    <name>V6DUT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cobalt-precorrin-6Y C(5)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C441_05589</name>
        <name evidence="7" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076998.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90646at2157"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11644">
        <property type="entry name" value="Precorrin-6Y-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012818">
        <property type="entry name" value="CbiE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02467">
        <property type="entry name" value="CbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="245" mass="26052" checksum="ACF6C35F2EFF0F4B" modified="2014-02-19" version="1">MTDDRPDAATAPEPPRDAVNDPVCAVGIGPGDPEYLTRRGARALREADVVVGFETVVEYVSDETDADLLTCGYDDEAATLDRFADRVRAGARGIAVLMGDPNHSGYQFVGKVERAIDEPVRVIPGVSSLQVAASRARTPMEDAAFVTLHKRGAIDADLDRLGDAVGDRHLLVLPRPFDWMPGDIAAHLIDAGGGPGLDALVFERLTHPDEAVTRTTLGELRESAGGTGRDSIPFSDLSVLVVRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT6</accession>
    <name>V6DUT6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4810" checksum="19C5107A75449948" modified="2014-02-19" version="1">MSRSHRCLYTDPQTQRRLDLDRDWGSGGLRVRPRPDLRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT7</accession>
    <name>V6DUT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiaminase II</fullName>
            <ecNumber evidence="2">3.5.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tenA</name>
        <name evidence="2" type="ORF">BN903_277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076711.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54038at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050334">
        <property type="term" value="F:thiaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026285">
        <property type="entry name" value="TenA_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027574">
        <property type="entry name" value="Thiaminase_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003170">
        <property type="entry name" value="Pet18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04306">
        <property type="entry name" value="salvage_TenA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="1">
        <location>
            <begin position="12"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="219" mass="24740" checksum="EA4F5D826F0AF340" modified="2014-02-19" version="1">MAFSDRLLDAGSEIWDAQKEHPFVVELADGSLDEAAFRHWVKQDYRYLLDYARVFALAGAAADDEETTRRLTGTAHATLADEMDLHRSFAAEYGLSPADLKAVEKAPTCAAYTDFLVRTAHEGSIAEIAAAVYPCGQGYLDVADHMADLASEEHRYTPFIEKYTSDAFRETVAWMRELVDRYGEAYPGERDAMRAAFLRSARLEHAFWGMCYDREEWSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUT9</accession>
    <name>V6DUT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03176</name>
        <name evidence="2" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="376" mass="40801" checksum="CC4189A1E578DB52" modified="2014-02-19" version="1">MDVNSHAEELASDLGVDKEEVKADLENLLEYSVPIDEAKQSVRRKHGGGGGGSTPTPDAVDVGEITTDHDGVTVTVRVLTQGTRTIRYQGDDLTIREGEIADETGVISYTAWQDFGFEPGDSLTIGNAGVREWEGRPELNLNDSTTVAIADEPVDVDHEIGGDRSLVEISAGDRGRNVEVRVLEVDEKTISGRDGETEILEGVVGDETAKLPFTDWQPRSELKPGADLRIEDVYVREFRGVPSLNLTEFSTVTPLPDAVEVADDAPRLSVADAVASGGMFDVEVVGNVLEVRDGSGLIERCPECGRVVQNGQCRSHGDVDGEDDLRVKAILDDGTDTVTVVLDDELTAEVVRGRPRRRPRRREGRDGQGGGRRRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU0</accession>
    <name>V6DUU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077001.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="21493" checksum="62DC90250833B27B" modified="2014-02-19" version="1">MYSRRATLAAAVAATTGLAGCQGVGIEVPGVGGGDELAQQDRRREVLDRYEAGIEGRNDGISTRNRAISLFNEEQYQTAVDEFETARTGFRSAATDLEAAVEAAAELDPAADSDGSGTNTSDGDDGNGDDGDSDDSPDPAAICERTLAEVQTQIEATDVGQAAAVAAVEEADGTTINDHIEEYRSLVEEASATSITEPEGLSEILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU1</accession>
    <name>V6DUU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03001</name>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077468.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100806at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018664">
        <property type="entry name" value="DUF2103_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09876">
        <property type="entry name" value="DUF2103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="29182" checksum="5C192A1B79B31247" modified="2014-02-19" version="1">MNCRRCGTPIEXPGDYCLTCNTANADAVVAEFESDRAHLTILDEDAVVGQTTVTTRPEEGERLSEVQLRNFAGRVADEIRWKRPETVYAAGERAPLRETRAQLHHEFYRVPDGGSSGRRGESTANGTRDGGAREDGEDVSPVVAWVLDRRGDRSLAVVETPPREKIGGSHSTLIGDRKGRKAVQTVAEHPHVKKIVPGPIDAGGTGSRTGLRAKATRAGTNGNVRLLLRDGSSVQENRIVTTAMDRETGERVREDLNEALRDAELQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU2</accession>
    <name>V6DUU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="6">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_10058</name>
        <name evidence="6" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077443.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88886at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="357" mass="37780" checksum="A3A4E1BFCA0D981E" modified="2014-02-19" version="1">MGTAPAQLFPEFIVDTLGLDSVIGEVAASLVAAFVVGNIILAFTGVAGPWAKRKITAAFTDRIAVDRIGPYGLLIIPAAAVQLLAKELIIPEGVDRPSWDIAPILLPASALLGFSVIPMGRIGPINLHLADPEVGFALVFAFASIASVSLVMAGYASNNKYSLLGGLRAVAQNLAYEIPLIVTAMSAVIFAGTLQMSGIVGAQTETLVTIGGITIPSWYAFVNPFAFVLFLTANLAEIGRNPFDIPEAPTEIVGGYQTEYSSAYFVLFYLGEFVHIFLGGAILAVTFLGGASGPGPESIGFIWFVVKIWGFFLFTQWARAAIPRVRIDQLIEIGWKGMLVLSFANLVLTAVIVGVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU3</accession>
    <name>V6DUU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9894" checksum="1C867C5A7CF6875B" modified="2014-02-19" version="1">MHREPLVRLDVEPLEEDERVEVLRVRPRRKRSIRVYARAVADRLAGDGSRSVRTRLTGSHVRPEPTTADKHHDYGTEKLSIKIGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU4</accession>
    <name>V6DUU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10649</name>
        <name evidence="3" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077512.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116783at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007236">
        <property type="entry name" value="SlyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04102">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="14207" checksum="3C9659BA06248478" modified="2014-02-19" version="1">MVDDDAEEEAESTAETTAEREAETEATDDVTIDVEAIDAYEQRIEELSTAVEEREDTIEELQSVVEEQSEQIETLENQFLDLSARVADGRNLGVCPECNGPTEKKERLFRSDTIECTRCGEVIHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU5</accession>
    <name>V6DUU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6945" checksum="8C79E24D1BB23E98" modified="2014-02-19" version="1">MRTTEGRGIYSRSGRTSDKSRGRDVALTADMSDVFGTVQEQFRGPNRSQTSISSNPRSPHQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU6</accession>
    <name>V6DUU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03026</name>
        <name evidence="2" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077473.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109198at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="16327" checksum="2692F9EA8F2A1CD3" modified="2014-02-19" version="1">MDPLQFLVPLGWLSAVGPVLPYAIFVMTVANLATRHLAHRRHVEQGQDADSVEAYNPHVFTNVGLVLLCFLFILDSPVSGTILSVLVLAMFIADFFELEARNVEARNDMEIEAPKSSIAASLVVLVWSSYYALFFVIEGIWNQFVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU8</accession>
    <name>V6DUU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoribosylaminoimidazole carboxylase, ATPase subunit</fullName>
            <ecNumber evidence="4">6.3.4.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_02721</name>
        <name evidence="4" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="domain" description="PurK_C" evidence="3">
        <location>
            <begin position="47"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14358" checksum="D4BE1C443240BA00" modified="2014-02-19" version="1">MLVNEIAPRPHNSGHWTIEGARTSQFENHVRAVLGWPLGPTDLVAPAVTANILGDIDETQPATLRNVETVLAAPDADLHWYGKDDVYPLRKMGHLTVTDAESDPDAVSVDERDALLDRTRELRDGLTLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUU9</accession>
    <name>V6DUU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_10679</name>
        <name evidence="4" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077498.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49614at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="29"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="382" mass="42522" checksum="7120088D68C5BCE3" modified="2014-02-19" version="1">MDPTPLQLGFELVSVGLLALLLVVVTLWQSFEIVDAYEKKTLTVFGEYRKLLEPGINLIPPFVSRTYPFDMRTQTLDVPRQEAITRDNSPVTADAVVYIKVMDAKKAFLEVDDYKKAVSNLAQTTLRAVLGDMELDDTLNKRQEINAKIRKELDEPTDEWGIRVESVEVREVNPSKDVQQAMEQQTSAERRRRAMILEAQGERRSAVEQAEGDKQSNIIRAQGEKQSQILEAQGDAISTVLRARSAESMGERAIIERGMETLEEIGKGESTTFVLPQELTSLVGRYGKALSGSDVQEMEGLDGKEFDADTRKMLGLDDIDEILGQIEESAEMNVEELEKEAEAVKAGDAGASIRSADEVIQEMDDEEAAAEVETDTEVETEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW4</accession>
    <name>V6DUW4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4308" checksum="D49E3B4BFC3E7CAE" modified="2014-02-19" version="1">MRPSDRNRSKVTASAAPDCQDRSTKCLFEFELKLRCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUW5</accession>
    <name>V6DUW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar nucleotidyltransferase II ( glucose-1-phosphate thymidylyltransferase)</fullName>
            <ecNumber evidence="2">2.7.7.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C476_00072</name>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077013.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78828at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="241" mass="27100" checksum="F9C70032BB479E74" modified="2014-02-19" version="1">MQAVVLAAGEGTRLRPLTEDKPKGMVEVDGKPILTHCFEQLADLGADEFVVVVGYLKEAIIDHYGDEFDGIPITYAHQRDQQGLAHALLTVEEHVDDDFMLMLGDNVFQANLEDVVRRQREDRADAAFLVEEVDWEDASRYGVCDTNKYGEITDVVEKPDDPPSNLVMTGFYTFTPAIFHACHLVQPSNRGEYEISEAIDLLIQSGRTIDAIGLEGWRIDVGYPEDRDEAERRLQDEEVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV30</accession>
    <name>V6DV30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6757" checksum="8DD4DC249BFCD004" modified="2014-02-19" version="1">MGTNSEYKAVAGFPRPGRNPRSVTVPVRREISRTMRVCHLPTVVKPPADADALRRSPPGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV31</accession>
    <name>V6DV31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07405</name>
        <name evidence="1" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="4955" checksum="B664B1499DAB0D27" modified="2014-02-19" version="1">MAVEAVVPVDATATATVEAIGFEAVGSGPRIDGASTTRYRFEPDGDAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV32</accession>
    <name>V6DV32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_17288</name>
        <name evidence="2" type="ORF">BN903_164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20524" checksum="FF2993A9B0471658" modified="2014-02-19" version="1">MTHGAVAYLLYVAYAAATTRRLPVRWALVPLAVGSQFPDLIDKPLAYWGVLVYGRSLAHSVFVLFGVCGGLWWVMRSESTPVGDRIPDRLREVAPAAFAVGYVAHLLGDAWGGLLAGDLASMRFLAYPLVSVPRSPSDDIAPWVRVLEIYREPAAAVQIEIVAAALVTFVGLRLWAARRGQWPRREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV33</accession>
    <name>V6DV33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5584" checksum="7778441CAEA6C6DC" modified="2014-02-19" version="1">MPPPRFELAETIDLAALGRCDSPAQIASGAFILLTVRSLRSLTSSQENAASPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV34</accession>
    <name>V6DV34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron/cobalamin ABC-type transporter ATP-binding protein</fullName>
            <ecNumber evidence="6">3.6.3.34</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C443_00442</name>
        <name evidence="6" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.34" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="30"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="208" mass="22661" checksum="2987E78823A85BFD" modified="2014-02-19" version="1">MQGNGKSRERKRSRKLPGDGMDETVSKTALDADDLVVGYPSTDEPVIDGETLAVPEGEVTALIGPNGSGKSTLLKGLANRLVPDDGHVLVDGRRIESFESKELARKLGRLSQQNTAPDTISVEELVERGRYPHRGFFESQTEDDEEAVNDAISMAGVEHLRDREVGTLSGGQTQLVWIAMALAQDTDVLLLDEPTTFLDPRPLQPTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV35</accession>
    <name>V6DV35_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_11990</name>
        <name evidence="3" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043902">
        <property type="entry name" value="DUF5786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19099">
        <property type="entry name" value="DUF5786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5786" evidence="2">
        <location>
            <begin position="3"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6466" checksum="E5873A1EE43DE470" modified="2014-02-19" version="1">MSMGAYDEAEHERREKKTSEVDADFDAERPEYSGSLTYDSGDSTEALLDKFEELQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV36</accession>
    <name>V6DV36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="5904" checksum="2BCCFAAF01186868" modified="2014-02-19" version="1">MTQAPQGASTASDRGAQRASARLAAGASAVTVVTRSAAYSRATGASVVFIVDTQSAIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV37</accession>
    <name>V6DV37_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07709</name>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077529.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101233at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="10"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16018" checksum="A91461C62D7918EE" modified="2014-02-19" version="1">MSIETVVLAVGTEDEKRAKRLANEIIAVAEPADAEVVLTHVFDESEFDGIREKLGVERGSEGSTPDAVAERHATTRALSKALSEAGVRHSVRGAVGDLADEVIETADSLGADRVFVGGRRRSPTGKAVFGSVAQEVMLSAPCPVTFVRETAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV38</accession>
    <name>V6DV38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
            <ecNumber evidence="2">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HalDL1DRAFT_2114</name>
        <name evidence="2" type="ORF">BN903_169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077047.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43299at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="307" mass="33463" checksum="5F79E773B4E884E0" modified="2014-02-19" version="1">MQDARILVTGGAGFIGSNLANHLADAGNDVLALDNGYLGTEGNLDEAVEYVDADVLDEDLPTDVDVVFHLAALSSRQMLEENPREGARVNIEGFVNVVEQAYADGCDTVVYASTSSAYGSRTEPSPEDMDLEAATGYDASMLGRERYAEYYNNFYDDLTCAGMRFFSVYQGYAGNEAHKGEYANTVSQFADKIANGESPVLWGDGSQTRDFTHVDDIVRGLIATADHGLTGVYNLGTGDPYSFNEMIDLINDALGTDVEPEYEPIPLENYVHDTCADISRIREATGWEPEIDFEDGVARVCEPYLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV39</accession>
    <name>V6DV39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C435_16740</name>
        <name evidence="1" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="28982" checksum="BFE70B631A42E709" modified="2014-02-19" version="1">MTNTMTEPDTISSSQIDRHLENVLSDTDGVGLPLIRETVNEPDDRWYGQLVVNSYVSLTDTPDLEIVLPVAAGAELLRGYVRLRSRLLATLADTHPHSLTLEPTPALLGGNYLYTAAFSSLHSAPETSSSDCFEILTTVLESITEAFARSYTSAGSADSDSTVFFDETAGSLGEAAAVLGATLAGVDESNRKHFERLGHGLSTVRQINWVLETDPSGALVIPPTLKESHLRTHAQQRQDDADHALDTLSATVDVTTLRAFVETGVSKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV42</accession>
    <name>V6DV42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5438" checksum="9252618B2F3BC8DB" modified="2014-02-19" version="1">MSIPWTTIGTRILFVSSGQFRESTIQPGSGPFWGDYLRKLDFKESQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV43</accession>
    <name>V6DV43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10693" checksum="835FE251F5A681F4" modified="2014-02-19" version="1">MISSRAKSGHNGTREAAAVRVRGRRLDARGDPPAGRAGIAVAGAVLRGVAHRPARRRRADCAVQRDAALAASAAPGDRGRARRVRLHRRAPDPRDPPEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV44</accession>
    <name>V6DV44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4498" checksum="D92D877B9AFFDD7C" modified="2014-02-19" version="1">MICNGVFATLLIDSCTPSSRRRSDPSSMRRSTANYGRATCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV45</accession>
    <name>V6DV45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="24310" checksum="9AE7746D0DAAC195" modified="2014-02-19" version="1">MNPSVSGGDDRATRFSRRLQPDMRICGRNADRPRPVDTLEANEETVQKCCSLELKRPSLGGIHVTPGRCRVDRERSGPTTERLSPMREGRNEETKHRGRLPVERRRGRGWTRSSVFDVSVTTRIRSRASVRSLASVPGAVGGVSAVNRIPSIILLSGCRISFSRSVGGLSPEPPARRLLYRSPCRGDSIDREPPHPFVSGGTPNRWGRGQGRLIYRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV50</accession>
    <name>V6DV50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein TetR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_07455</name>
        <name evidence="5" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077558.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62280at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="4">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="227" mass="25863" checksum="D1B74C10992563E0" modified="2014-02-19" version="1">MSESQGGSASESAESPTENADADEGSAGETVSSKDTKEVIMEATFRALSKHGYKDLRMRDIGEEMDLTRQVIHYHFDGKYDLMSSFLEHIIDQYEGSVVVDGDADPRTELRARVDQCLFGPEFEEFSHWDRMKVYHELYTQAQNDGDHREIFNEHYERIRGSIVEVVEEGIEEGVFRDVDAERMGQLVTDVIHAARGRRISLGHEDAPEEARKAIDEFILESLEQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV52</accession>
    <name>V6DV52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07610</name>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="5772" checksum="B7E576F5F27D1EDC" modified="2014-02-19" version="1">MELISIAGLLLHSGTEHPDTLWIALTGVVAFALGVAVGRCGRSVSLPVGPSVGGSDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV53</accession>
    <name>V6DV53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BNR repeat-containing glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07435</name>
        <name evidence="2" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077561.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37909at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="366" mass="40170" checksum="B5A2E39FBE6D3E99" modified="2014-02-19" version="1">MTLLIGTDSGLYRADDVPFERDELDPVLDCGVVTAVKSWDHTEGVFVASSTGAYRSLDGGETWTDLEVPLGDRFWHAGQSEVWSILATADGALYAGTNDPYIFRSVDGGETWTEQKGFRELPSRGHWESPIDPHYARLRALETVPGRPDTLIAGVEAGGIHVSRDGGRTWTDHRDAIVDDVHQVLPISEDVWLAATGYLDHDLENLGLGHAVGEGGLWRTTDAGESWDRLDVGSDFSYIRRVFVHDGRVIFCGGEEAPPAWVNDDHEVALFESTNFGRDFERVSFPGEPHEIIETWAVHDGDVLCGSGLFDVPDERDDVEGRIMRRVDGEGVDDESDEGDGGEGDGDPTYETVGRVDANVSRIEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV54</accession>
    <name>V6DV54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8716" checksum="6338FE02B262C393" modified="2014-02-19" version="1">MRMSYQTGTAETSVGFGVVVLLIGAALWGLQFAFGVFAGWGWALAVGSAWMVLGVLLLFPDVRLYTGTRSPAETYHESVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV56</accession>
    <name>V6DV56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_09953</name>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018645">
        <property type="entry name" value="DUF2072"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09845">
        <property type="entry name" value="DUF2072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="15014" checksum="5B0630D3FD298B97" modified="2014-02-19" version="1">MRLVSGPWRRSAATAASRSSSXXXXXXXQIADRSDEDTAQASARSEVVSPDELDRASREVEGAETPPADEEPQSGIDALRDELNDQFESIRIVSPGQYELNLMELYDRQEYIISLQEDGRYVIEMPDAWGIQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV57</accession>
    <name>V6DV57_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07585</name>
        <name evidence="1" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629199.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122578at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7541" checksum="81D9C157BC9D3AE2" modified="2014-02-19" version="1">MVRKKKLSPSGAKDDEGEYHNVHVNLHEDELAVAGMDIGDEVFVRVRDGKIIIQKADANPDQLEHDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV58</accession>
    <name>V6DV58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03876</name>
        <name evidence="2" type="ORF">BN903_195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077065.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98304at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="22131" checksum="D8D1DF57678EA3E7" modified="2014-02-19" version="1">MNPTRRRYLRGVGGIGGAACLAGCASDGPGDDGGDGDGESDDSGGDAGGTRPEGTGGPGVSIVSTDGDVGLPVDLGVEVVREAATADHPPRLRTTLTNASDRRVRVGEGRAVHFEYVSDGSGALTFLPVDMEAPAEPDCWRLTDSIAVTEEYRTFELGAGESRSRSIDLYATPTDTDACLPVGEYRFETTVSIVSDDAEPQSSAEWGFSVVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV59</accession>
    <name>V6DV59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Creatininase</fullName>
            <ecNumber evidence="4">3.5.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Hmuk_0945</name>
        <name evidence="4" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.10" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076834.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35243at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047789">
        <property type="term" value="F:creatininase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="267" mass="28988" checksum="AF5B633213E771BA" modified="2014-02-19" version="1">MIYETIGTNEWEWAGKPYAAIRDIAQRDGSVLVVPVGSVEQHGHHLPVITDTLLVDAIVHGGAESLRDDVPVLVTPVVWSGFSPHHLSFGGTLSLEFEHLRRVLEDIGRTGLENGFDAVCFVNGHGGNASLIDATVSTLGKTTDAEVLGTTYFNLAAPEIGDLRDSEPGGMAHGGEYETSLMLYLRPDLVAEPMIEDGTRWDEHYDWGGGDLLEGGQLSVYRPFEEYSDTGDIGAPELASRGKGELIYDIVTDELGAMFTAIHEHNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV60</accession>
    <name>V6DV60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain/neutral amino acids amide ABC transporter periplasmic substrate-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08480</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="157"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="347" mass="36324" checksum="725D2E46D0067F56" modified="2014-02-19" version="1">MNNVIGTAPSAGGPGADFFAESYQDEYDEEPGVFTSQAYDAMAVEILAATAAGENNGEAIRDRVRTVANPGGEEFGPSNLPEAVEAVAAGDPVHYVGASSSVNFDVNGDMATAAYDITDFQDSELVTLDTVEFGNELSEEDRNATAADPVGVDSFTARIGVLMPETGDLGPLGGPIRDGALLAATQVNDAGLNVDVETRVEDTQTDPQAGDLRRERLVNAGFGAVVGPASSNVNLQVSDQVFIPNGVVGISPSSTDPNVTDLDDNEYIFRTAPSDLLQGPAMADLAVGDVVGASTSGTLYLNDAYGQSLEESYVNAFEERDGTIDQRVSFEPNQATYTSQWSSVLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV61</accession>
    <name>V6DV61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07380</name>
        <name evidence="2" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077570.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105319at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024464">
        <property type="entry name" value="DUF2391"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09622">
        <property type="entry name" value="DUF2391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="15659" checksum="79139FEE416D33D1" modified="2014-02-19" version="1">MKRPKSLRRPNFRLADSAQQAVGGFLLAGPFVVTEEVWVLAAGMNWTQAVLVAGLVAAIGYAALYRADTDRDPETETEIAGIPVRFLSLMIVAFGSVLLLAVLFDAPDTFLIEQGVVGRELWMTTLKAVSVGAVFSVVGAATADSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV62</accession>
    <name>V6DV62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4440" checksum="F85219971DDDBFD9" modified="2014-02-19" version="1">MRQDLLTTQRVDPKITTGFGAPTASIVGHMLLNQLSSGDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV63</accession>
    <name>V6DV63_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_03846</name>
        <name evidence="2" type="ORF">BN903_199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077068.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84281at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019278">
        <property type="entry name" value="DICT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016954">
        <property type="entry name" value="Uncharacterised_Vng0742h"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10069">
        <property type="entry name" value="DICT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030471">
        <property type="entry name" value="STR_Vng0742h_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DICT" evidence="1">
        <location>
            <begin position="123"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="255" mass="28230" checksum="441341F884130767" modified="2014-02-19" version="1">MAESLRSFFDELESPDRHLVLLNRSSPDPVLGLLDSLLDGQSVSISEAVSDDAGDDDVVALVENGTVIARSSLDELLESVLLINSDLYKTGAIELDDVALPDVFRGLDEVPFRVRSYPASNKEKLLLIIISRVIERIAAEHGDGTLRASFQRLSRIDDERGTRSVYERVAGTDVDVHVYGVGDVESLSTLPVTVHSGTSYPYRRSWFVVFTPPDGGDGDHVALLALEDEPNVWDGFWTFRPELVARIERYIAEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV64</accession>
    <name>V6DV64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12021</name>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="178" mass="18856" checksum="981E294A3FD3C274" modified="2014-02-19" version="1">MEPDGHALRSALYKRADVFRSLADAPASKPELVDRLSSSRSTVDRAIADLEDVDCVESCGGTYSLTATGRFALAEHDRYAAATRTVERAAPLLNELPDDASLPSAFLTGATVTVADPHAPSEAATASSELLERATAMRGCSTVLKSDVFILNRGARSRRTQRGGDRRXGGGRGALRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV65</accession>
    <name>V6DV65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_16356</name>
        <name evidence="2" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10575" checksum="610111845980FEDF" modified="2014-02-19" version="1">MSSNSYVSTERSDGSNCHIRDGAAVTTHLTTDVSRRGASKTRYETLEEVQSYVEALIEYRDQSVDTDDLPGTAELVDEPDSIGNGTVVKENITCGDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV66</accession>
    <name>V6DV66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07348</name>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077574.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101231at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="21"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="14024" checksum="83BD294008F709AF" modified="2014-02-19" version="1">MSDPEIEDLVGDRSPSFEHVLSCVFGVRDHESRAYLALLDNPGSTVSELADALDRDRSNVNRSLSTLREKGLVERRRRLLDSGGYVYQYTAIPVPEAKRRLHDALDEWVGDVHDAIDAFDPDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV67</accession>
    <name>V6DV67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5104" checksum="18F9EBC4EA480115" modified="2014-02-19" version="1">MAAGRDRSGQLGVPRWRAPPSALLRARGASREGVGRRSEATAADEAGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV68</accession>
    <name>V6DV68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_11991</name>
        <name evidence="1" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043953">
        <property type="entry name" value="DUF5784"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19096">
        <property type="entry name" value="DUF5784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="191" mass="21711" checksum="8A853573CD666B13" modified="2014-02-19" version="1">MVRAAARLRGASVRHGRRVVRAVLLDRRRRRPSARHRRGPVGYWLGNTETPSELWRTEKYGFDEAPYPVSRWAQRELLAALHDDEPWLADYPHVSWYFLPVFCSKDGAETSRAFFRDHAAGFPDATREDGTRFVEETLRPGVLDDYRETMAGKLGTSASLDLVRMSATIAEFTAARILTEAGYGVTPRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV69</accession>
    <name>V6DV69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C492_00020</name>
        <name evidence="2" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334929.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="34662at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="569" mass="59095" checksum="04C225398F79D92D" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV84</accession>
    <name>V6DV84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6253" checksum="CF99723B0B101E36" modified="2014-02-19" version="1">MVPRLHGGDDPAVEDGVEFVALEGDVVGSVQSGVCPDQQCHIRVSAGRIIKFYQSVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYZ0</accession>
    <name>V6DYZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6038" checksum="05B587234DA9CF55" modified="2014-02-19" version="1">MAKWCRCRLSISERRFGEGLQSPSREAGARSLRSSSLASLVPAVLTLPAPASRLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYZ4</accession>
    <name>V6DYZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin</fullName>
            <ecNumber evidence="3">1.13.11.53</ecNumber>
            <ecNumber evidence="3">1.13.11.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_11045</name>
        <name evidence="3" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.53" evidence="3"/>
    <dbReference type="EC" id="1.13.11.54" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078433.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000031.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105481at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010308">
        <property type="term" value="F:acireductone dioxygenase (Ni2+-requiring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010309">
        <property type="term" value="F:acireductone dioxygenase [iron(II)-requiring] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="47"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13371" checksum="C6546B587483C83A" modified="2014-02-19" version="1">MSDAVEPDPVVKRGDDVASEPVDAADGLSKAVLLDESDGAPNFAMRRFELAPGAAVPRHTNAVEHEQYVLAGEYVVGIGDEERVVSPGDALLIPAGVEHWYRNEGDEAGAFICVVPNGDDTIELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYZ5</accession>
    <name>V6DYZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04912</name>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="9537" checksum="EB92BD817767A25F" modified="2014-02-19" version="1">MTVRTRPLASPRICYRGMSLETMEQRDARFVLLSTLLACILLNTLDAPTTRWFRTASFALAYATLLYAGYVVVRPRLEWLPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYZ8</accession>
    <name>V6DYZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7774" checksum="E6DDB394463EABE4" modified="2014-02-19" version="1">MIYHELFTTIYCDFELLMPVRVLSVDVMTDIKTIYKNGSVRLKDTPRPEDLDATTSPVARLVDWLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQE8</accession>
    <name>V6DQE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_06679</name>
        <name evidence="3" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076275.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89753at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="233" mass="24764" checksum="7A8D151AE5F01D64" modified="2014-02-19" version="1">MKLFSSRADRRRGIAAAVGVAVLAVGLYVLVSRYAGFLTDRQALRTWLDGFGVFAPIVFIGIQALQVIVAPIPGQVVAVVAGYLFGSFWGTVYSLTGVLIGSAVAFSLSKRFGRSFVESVLHEDVVARFDGFVDTVGIPGLFAFVVVPGLPDDAICFLSGLTKWSLPTFIGVIAVGRLPAYVLAVHAGGEIANGQFLSAIALLALIVVASAVGYYKQEAVRDLVERIEPRLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQF0</accession>
    <name>V6DQF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4538" checksum="CF635F85D23DACA5" modified="2014-02-19" version="1">MFTHICPLVEGRYNLCGDETRTVFDAMAAESLLRSENTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQF3</accession>
    <name>V6DQF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="169" mass="18109" checksum="B2E3A5C22CBE3D22" modified="2014-02-19" version="1">MPGDHRQPERVHRVVDGGVGGRRLAPSVVVGPGFGVDQLSADLSERRARIVDVAVERGXXXXXXXLSPVCLASHDSRQICPSVAPGSSTWPSSAARRSPTPGAVVFERSRRRPFSPRKHTSGCASVTCFRAVSSSWRNASTAPTAGAMWYDCRLSPLSRSARFCSLTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQF5</accession>
    <name>V6DQF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6101" checksum="10DD32B5F50C09ED" modified="2014-02-19" version="1">MRYSSSRTSIRFQRTGRYHSGFGLSPRPRSVGSNGPYGVSTEGNSVTVPRYVVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQF8</accession>
    <name>V6DQF8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_06609</name>
        <name evidence="5" type="synonym">cetZ</name>
        <name evidence="8" type="ORF">BN903_134</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CetZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="2"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="392" mass="42164" checksum="21D8C9E1C37119FF" modified="2014-02-19" version="1">MKLAMIGFGQAGGKVVDKFLEYDKRTGSEIVRAAAAVNTAKADLMGLEHIAEDQRVLIGQSRVKGHGVGADNELGAEIAEEDIDEVQGAIDSIPVHEVDAFLVVAGLGGGTGSGGAPVLAKHLKRIYTEPVYGLGILPGSDEGGIYTLNAARSFQTFVREVDNLMVFDNDAWRKTGESVQGGYEEINEEIVRRFGILFGAGEIQQGQEVAESVVDSSEIINTLSGGGVSTVGYAEEEVEERSSGGLLSRLRDDGNDEELDSAHTTNRITSLVRKAALGRLTLPCEIEGAERALLVLAGPPEYLNRKGIERGRKWLEEQTGSMEVRGGDYPYRGAGFVATVILLAGVTNVPRIKELQQVAIEAQDNLDEIREESDENLDELVSDDSDELESLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQH2</accession>
    <name>V6DQH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_14444</name>
        <name evidence="1" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076240.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121854at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10693" checksum="49F133008E8AA276" modified="2014-02-19" version="1">MRLPETRDLFARELDFPASRVTVLERVGNTELSPPDGESTTIREIVERSEVTEFDSADDLYDTLMSLVGPQFVGRRYYDDRGGMPGDEENEVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQH4</accession>
    <name>V6DQH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoid protein MC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hbor_03160</name>
        <name evidence="3" type="ORF">BN903_149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protects DNA against thermal denaturation and modulates transcription.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008674">
        <property type="entry name" value="MC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036620">
        <property type="entry name" value="MC1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05854">
        <property type="entry name" value="MC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102875">
        <property type="entry name" value="SSF102875"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MC1" evidence="2">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7631" checksum="7D052CD276D6902D" modified="2014-02-19" version="1">MDPSSSYERAKEQTTEIRIREKGTDKVYIYDAWAWEEDAPADAPDWMPEQITEANVSKQGVRHMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQH6</accession>
    <name>V6DQH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiamine-monophosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_01227</name>
        <name evidence="3" type="ORF">BN903_147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS_C" evidence="2">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="11871" checksum="9115318A06EE2076" modified="2014-02-19" version="1">MDSSDGLARSCHQLVEASGVGIELDREAVPVHPAVEEVAAGADERFEMAAHFGEDFELLCAVPESEVAAVREACPAGLTRIGRVVEEDGAEAGPRVTADGEPLPDRGYTHGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQH8</accession>
    <name>V6DQH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase class I and II</fullName>
            <ecNumber evidence="5">2.6.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_12407</name>
        <name evidence="5" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076245.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51060at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="41"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="383" mass="41862" checksum="325E976CC28AC5B4" modified="2014-02-19" version="1">MRIDPFGLERWFAEYEHEADIMLAESGIRSLDASRFDLDPGKLGYVIPTNGDPDFRESVGDRYDRSADEVLFTCGTQEANFLTFLSLLGDESGLGEEEVGSGTHAVVVTPTYQALHAVPDAFGDVTRVELEPPEWKLDPEAIADAARDDTAVIVVNNPNNPTGQYHDEAAMRAVYDVAVERDAYLLCDEVYRLLAEEPQPPVASYGAHGISTTSLTKAYGLAGLRFGWIAGPEPVVERAWRWKDYTTISPSLFGQHVAKQALGRREDRILSENRELAAAHRDRVADWVDDHDLDWLDPVGVNAFVTVPDGFDDAESFCRTVVEEASVVLAPGHLFGFPDRFRIGFGLPTKELEEGLDRVSSVIESAGGASAEGDAATRGGGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQI0</accession>
    <name>V6DQI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside recognition domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01182</name>
        <name evidence="2" type="ORF">BN903_154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038880">
        <property type="entry name" value="MJ0871-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38139">
        <property type="entry name" value="PTHR38139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="12892" checksum="156126C2A955346A" modified="2014-02-19" version="1">MYTLVIWLVSTYDVAGLTSVAEPITGVLGLPGAAVPVIAVFTLDTTAGAVTLAGTEAGVFTTRTAVASLLIGSILSFAVSTFRRSIPFQYGIWGASFGTKVIVVNTGLKLVFISATVALLLAPVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQI2</accession>
    <name>V6DQI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_00242</name>
        <name evidence="2" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076249.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83294at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="319" mass="34884" checksum="44A752E16AFA036D" modified="2014-02-19" version="1">MSLRSTIDRILPTALRQRVFQLLWPVWNTEQRRLRAPLRALLPTVLTFILLGILQTAIRARFEHPVRELLELTGIGVILIGAILLSARVIDRRPVSEFGLSLDREWWHSFGVGGLVATAINGGALVVSLGAGWATFVGVMRGSGDLPFVPAMMVVFAYIALAATWEEFIIRGAMLKNVAEGSSGFVSQWIAVGLAVTLSTLVFAFLHGGKITNPSHYGYYLIAGLVISSVYVLTGELALSIGFHVFYNFTQSAIFGLGHSQQTPELFAVDIVGPSRWIGEEGLVFVGFAVLGGLVLMAYIYWRDGSLQLDDRVTSYVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQI5</accession>
    <name>V6DQI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen</fullName>
            <ecNumber evidence="6">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_06372</name>
        <name evidence="6" type="ORF">BN903_160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076296.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98508at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="2"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="16641" checksum="9DB6E4677E34B95F" modified="2014-02-19" version="1">MVSTGDAAPTFTATVGTSDHEPFDLDEEIGDGPVVLAFFPGAFTPPCTNEMIAFQERADAFADAGATLFGISADSPFSQGAFREEHGIEFDLVSDMAGDAIRAYGLEIDIADLGLHGIANRAVFVIDDDGEIVYDWVADDPTNEPDYEAVLDAVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQI6</accession>
    <name>V6DQI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="8480" checksum="B638190FA5F8963F" modified="2014-02-19" version="1">MSLDNTRLPSGDIFIKYNDSLGEMRIRLGRGRTIGAKNSQRVSAVDSGQERGVVPVGSGREVGKETRRFRPGACRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQI7</accession>
    <name>V6DQI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MCP domain-containing signal transducer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_01417</name>
        <name evidence="8" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076252.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48798at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="94"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="159"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="298"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="403"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="439" mass="47366" checksum="9DE0F8AABD941CD1" modified="2014-02-19" version="1">MAAVTQNDQLQAAETASDGDFWRHTFEQFIAELPEAAFVVDAAGDITQWNETTAELLGLPASEAVGMNAYDVFGTEGKDETLAEEVVRTGTAIREDEFRSAERPDGTQAHARAIGTPIQTPTGEVVGAVELLFDVTTVVEQRETLSDLQEELSDNVETSMAQLGESTSEVADRSNEITQLVSEQAAELESTQSDVSGFSATVEEIASSAEEVSTQSAESRELAEDSVETADEVIDQVDDTAEKSATVADDVAELKGEIEQVEELVGVINDIAEQTNMLALNANIEAARNDSDGFAVVADEVKNLANRSQDQADEIEEIVTRIKAKATRTTDEVEAANDEIQSARDDIQGVLENQKQILKAVEQTESGISEIAAATDEQASVAEEISSAVDDVSDRAHVVSDEIEEIADENESQTEMVTRLTREVEDIDRQLANVMSRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQI9</accession>
    <name>V6DQI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H</fullName>
            <ecNumber evidence="2">3.1.26.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_11082</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="77"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="22212" checksum="5E0CD8288141F978" modified="2014-02-19" version="1">MEQLPAARLSPLANQVDNVLAQCGYEIRRGIDAIDDAVVGYGGLFEPETTNNEIRAAVEEVLANNTPAATDGVLGSGGCDLVLYVDGSSRGNPGPSGAGAVIQVGDEGIINLGRPVGSNTENNLAEYAALQMGLEVALTRCNPKAVEVRIDSMTVINDIWGDSDGLPSADVFRDTIVDHVSSLPKCEWTHLADSDLNPADARATVGADIAALGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK4</accession>
    <name>V6DQK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_03452</name>
        <name evidence="3" type="ORF">BN903_167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="45"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="24158" checksum="73F016A8D7C02F05" modified="2014-02-19" version="1">MPEDVLVTADWVEERLDEFQDDDSDHRLVEINNPTVTDESEYTPYEEGHIPGALNFEWDAVFTDETERDIVSKENFAARNGEGGIDADTTVVVYGGGRVPNWFALFGYWIYKYYGHDDIRVIDGGKGYWVANDYPLSTEEPDFTPREYEARGPFESVRAYKDDIDKAIEEGIPMVDVRSPEEFSGEVIAPKGSTRRPSAAVTSPERATSRSGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQK5</accession>
    <name>V6DQK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_08845</name>
        <name evidence="2" type="ORF">BN903_179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076470.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67791at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="150"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="30745" checksum="55E3C4D0D607B781" modified="2014-02-19" version="1">MRALCATDLSAASEAAIENETCLTCLARIGVDTIHLVTVVPANVHSGMPGVNFEERRRQGLDQYRQVIEAAGFDVETHVVRGTPYRRINGIAETVHADLSVVGSRGQSPLKNRIIGSTARNLARTTVVPLLVNRVERATDEPDVLREHLFQRILFATDFSENADRAFDAFSYLRHATEEATLVHVRSPKDEGVDDVSPREQLADHASTLENWDIETRIEVRQGDPAAEILSVEAEVTPSTILVGSKGRSRIRRLLLGSVSEEIVARATGNVFLVPPPRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN0</accession>
    <name>V6DUN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase hydrolase</fullName>
            <ecNumber evidence="2">3.5.1.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_05568</name>
        <name evidence="2" type="ORF">BN903_208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.107" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076928.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79386at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="221" mass="24565" checksum="7D44FB745879CCF0" modified="2014-02-19" version="1">MTNRIWEDLLTERDEQVISAAGYDKEGASSWESRGMGTNPMVLVIDMQRLVVGEDEPILDAVEEYRTAMGSIAWDAIDHIGPFLEFARDHEVPVTYTRVVPSSYDDPHHEDLDIVDAVAPEAGETVIDKSYASAFYGTDLLSRLVWGGHDSVIIVGNSTSGCVRATAIDAQQNGFNVVLPQECVFDRIEASHKIALMDLWMKYAEVLERDEVESWVGGIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN1</accession>
    <name>V6DUN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4636" checksum="65D7472BDFA04CCE" modified="2014-02-19" version="1">MVGRPIRWSKVVSVGVSTWSSIRVIATDGDQILGLFFGNDASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN2</accession>
    <name>V6DUN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_15251</name>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8317" checksum="5A1063E387247E5B" modified="2014-02-19" version="1">MTVRVSRTFEFDAPPADVWAFISDAEQRAGAISVVDSFEVHDDGSATWHVALPIPMIRSTIDVETEDVERDPRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN3</accession>
    <name>V6DUN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11962" checksum="A2A37F842C44809C" modified="2014-02-19" version="1">MGLAVDGHLSLLHRLQQRGLRLRRGAIDLVGEDDVREDRSRREREGAVALVEHVGPGHVGGEEVGGELDPRELQAERGRERARREGLSGPGHVFEEDVAAGEDTERDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN4</accession>
    <name>V6DUN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4728" checksum="D5697CEB3F6162EC" modified="2014-02-19" version="1">MNIRPIISGFKRITASKSDNIREKRHVRSETRRCLLPEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN5</accession>
    <name>V6DUN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4636" checksum="E959C1DE8D766318" modified="2014-02-19" version="1">MRNDDQWCGGACLRAVATGDREAAPREGVGRRSEAEATDEAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN6</accession>
    <name>V6DUN6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
            <ecNumber evidence="5">2.3.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_09978</name>
        <name evidence="8" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.16" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077431.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="39666at2157"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011278">
        <property type="entry name" value="2-MeCitrate/Citrate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01800">
        <property type="entry name" value="cit_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="382" mass="41540" checksum="47761CA26863D17A" modified="2014-02-19" version="1">MADELKRGLEGVLVAESDLSYVDGEVGKLVYRGYDIEDLARGASYEEVLYLLWHGSLPTAAELDAFAADLAAEREVDDDVIETVRALADAGERPMAALRTAASMLSAYDPDDDESGDDGESTLRQGRRITAKIPTILAAFERVRQGEEPIAPDPDLSHAGNFLYMLTGAEPDAVSEETFDMALTLHADHGLNASTFTAMVIGSTMADVYSGVTGGIGALSGPLHGGANQDVMEVLHEIDASSKDPVQWVKDTRDAGGRIPGFGHRVYKVKDPRAVILEEKLRDLAESSGDTKWLDYTTAIEEYLTDQGLLDKGIAPNVDFYSGSVYDSLGIPVDMYTPIFAMSRVGGWIAHVAEYQEDNRLIRPRARYTGPEDAEFVPIDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN7</accession>
    <name>V6DUN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04672</name>
        <name evidence="2" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="34505" checksum="028DDBD7A672B199" modified="2014-02-19" version="1">MSIDIDPLRETDGITVTDHIENTQFEVYTDRPVDPRPRPGSDHYFPVDASVAVETGSIEIPRVAVVETRASDGTLLTHGDCYAMPDGTYHVGINPAPTKLYFAFESGFSVSTTDRTTRIDLDTPGTVALGFRSLHQTPAGTITTPTDPESLMDAVSLLGSALQTTSPERSFPTLRGHPPLIEPGEEFRVPERVEPVDSGVRIVVPPEYRYLYPVVSLAYYFAAEVVPGDAPRIEGDGWTYPLEPGFEARTAEVLRQSFHMDCLTRAEGFYPSTSTSARRPTSTSTGSGCTTSRSRSGSASTSTFPSRRSSRSCRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN8</accession>
    <name>V6DUN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
            <ecNumber evidence="3">3.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10224</name>
        <name evidence="3" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629705.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89031at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="119" mass="12988" checksum="50B037D536897A94" modified="2014-02-19" version="1">MTERVLVVDDSSFQRTVVRDALADRFEVVGEAENGAEAVELFEAYEPDAVSMDVVMPEMTGIEATAAIKDRWPDAVIVMCTSVDQQEKMMEAVKAGADGYVTKPVDAEELVGEFESHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUN9</accession>
    <name>V6DUN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04228</name>
        <name evidence="2" type="ORF">BN903_227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="263" mass="29758" checksum="8EE180A549594FEB" modified="2014-02-19" version="1">MDSGGSTDMTLAFELEALKALADPNAVFSNARQWTEYVGVVSEKPTYVVTNFTRKHRVRQDFFSGPRGVEESLENISGQFDTDRHVFVGVDDEDEAVAEATGWGVPPRRGRRRGRGVDARDRRDRGRGGRGAGPRRLAVARSRGRQGTQGIGXXXXXXXDESRPRKRRGARRTRRRPRGRPRPSPPRRRLRRGRGRHRVVVAERGRGPGGRLRRGRLRGGGPRGRRPRTDPGRLRQRSGDRRQARSTEGHRRGGDHRRHGRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP1</accession>
    <name>V6DUP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_06327</name>
        <name evidence="2" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF_alpha" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6037" checksum="0E9F97A05828D9AF" modified="2014-02-19" version="1">MYLAIGISGAVQHVAGMKGSDTIIAINTDPNAPIFDIADYGIVGDLFDVVPALIDEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP3</accession>
    <name>V6DUP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4660" checksum="C7EC736955DF945A" modified="2014-02-19" version="1">MEQHGPRSCNERSRSGVPSRLLRGGGVRAQGVFLLWRALLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP4</accession>
    <name>V6DUP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_02856</name>
        <name evidence="3" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077456.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100454at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="360" mass="38910" checksum="F75026FA8BE423A6" modified="2014-02-19" version="1">MSSRGTSLRDRIREPEYTGENRCVPCTVLNVVLAAALTAAAAVFGPVVAAAVLVASLGSIYYRGYLVPGTPELTKRYLPDRVLRLFGKAPEGPRDGWERASTGGSDEVTVTTFEADRTAEGTSEVAERSAAEVSDGSADDNSDQSADESEDRSTDETDHDSPAGDEPEFETVERIQDQRENAVDPTEFLLDIGVVKPTDDGADLVFEESFAEAVESRVSSLEREDVRAETLAEMFGVSPDDVAFEDREYPAVTVLRRVRKWPGDGAYLADVASHLALVERTDRWLDVPAEQRLSILQSLRSFLSSCPVCGGEVAATADTVESCCMAHEVVAIRCESCGEHILELEPEKIATPGEDTGITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP5</accession>
    <name>V6DUP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AsnC family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C473_16147</name>
        <name evidence="5" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004598227.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="GeneID" id="64828090"/>
    <dbReference type="OrthoDB" id="97695at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="16766" checksum="76838A79372B2EC5" modified="2014-02-19" version="1">MELDETDRAILRILQEDARTPFSEVARRIDMSSATVHDRVSRLEEAGVIRGYHADIDPKAVGYGVGAFVGLRVEQGREEDALERLRGIDGVREIHLTTGEWDVILRVVAADTDRLRELMFERIAETEGFSRSQTMVILGTDYEQPGPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP6</accession>
    <name>V6DUP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_02345</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077084.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9887" checksum="0A217BFADA0B4C4D" modified="2014-02-19" version="1">MLVLLESLSFYRNVRVGAAVGALLAVLLYLVRTLELLGPVIDTRDYPLFGPDVWFLLLAFVLAATSALSVAIALTVAAAVRGARETDAERPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP7</accession>
    <name>V6DUP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH-ubiquinone oxidoreductase chain 4L</fullName>
            <ecNumber evidence="6">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C473_15106</name>
        <name evidence="6" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077441.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125081at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11434">
        <property type="entry name" value="PTHR11434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="11505" checksum="E5A5AAF8F62FAA62" modified="2014-02-19" version="1">MTAIAASIPPSWYLLLASAVFCIGLFGVLTRRSALYFLMSVELMMNAANINFVAFALYYGDLTGQVFALFVIALAAAEVAIGIGIILVLYRNFGTTDVTVPAEMRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP8</accession>
    <name>V6DUP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4933" checksum="D4FFB6B9A3117002" modified="2014-02-19" version="1">MPPSELVGGGCATTRDFAQTGPRKAVLNSENRAGILMRRTRSAWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUP9</accession>
    <name>V6DUP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monovalent cation/H+ antiporter subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_12891</name>
        <name evidence="3" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="2">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="259" mass="28288" checksum="EABD9AC3E0EA411C" modified="2014-02-19" version="1">MWLAYLGGFMAVYGAFFALLQYDPRRLLSYHIQAQVGYMLAGFGLATYVGDFAVVGGFAHLFNNVLYKSLLFMAVGVVIYRTGVEDIREMGGLWRVMPVTFLVYLVGAASITAVPGFNGFISKGMVIDSAHEVHNYVLLLDSGLLWWLLILGGVGTFMSFIKLGYYVFFHGSATLSPDDATAFQTGGMLLAAGACVFFGVFYGQLIELMPFTEFIRGDEVYFNPYSQSHLTESAALLVAGFVGFFLAEAPARVGRPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ0</accession>
    <name>V6DUQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oligopeptide ABC transporter solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C461_10493</name>
        <name evidence="3" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077504.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6658at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="222"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="594" mass="66332" checksum="4A622D9B7EB60F0C" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ1</accession>
    <name>V6DUQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein</fullName>
            <ecNumber evidence="2">1.1.1.95</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04196</name>
        <name evidence="2" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="15033" checksum="70F4B81B1FE9DB6C" modified="2014-02-19" version="1">MAEHGVEKVEFEELFDRADHVGVYAPLTDATRGIVDADALSRLSEDSVLVNVSRGPVVDADALLDALEADKIKAAGLDVLAEEPPEDDPLVGRDDTVITPHAAWYSEEAKDDLNRSGAADVAAVLNGETPDGRVDPDADWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ2</accession>
    <name>V6DUQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenite-activated ATPase ArsA</fullName>
            <ecNumber evidence="3">3.6.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10354</name>
        <name evidence="3" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077465.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84406at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ArsA_ATPase" evidence="2">
        <location>
            <begin position="329"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="384" mass="40591" checksum="987647955527CF6F" modified="2014-02-19" version="1">MDDIDVEPVDRVDEADDSVDAPETADSDTAVVSEAVADLPAGVDAPDYVLYGGKGGVGKTTMAAATGLASAAGGVRTLVVSTDPAHSLSDTYETEIPAEPAQIREDMPLYAAEIDPDAAVDEGMFGADADPLGGLGEMGDAMGGMGGDAEAPGDEGGLGDLLGGTMPGADEAAAMRQLLEYLDDPRFDRVVVDTAPTGHTLRLLQLPEIMDSMLGRVMKLRQRFSGMMDGIKGMFGGGDDDPDPSADLEALRERIERLRAVLRDPAKTDFRVVMIPEEMSVVESERLVARLDEFGIPVNTLVVNRVMEGVGDVTGGGATGIDPDWVVEPNPDSCEFCARRWDVQQNALREATDLFRGRDVKRVPLLANEVRGEAALRVVAACLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ3</accession>
    <name>V6DUQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein</fullName>
            <ecNumber evidence="2">6.3.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05050</name>
        <name evidence="2" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077407.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101215at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="Alpha_ANH_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022427">
        <property type="entry name" value="MJ0570_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="PTHR12196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039123">
        <property type="entry name" value="Diphthamide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03679">
        <property type="entry name" value="arCOG00187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthami_syn_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="237" mass="25849" checksum="CA7BBC725DD60A69" modified="2014-02-19" version="1">MSDWVSLFSGGKDSSWALYRAVEEGLDVSRMLTVHPAGDSYMYHTPATELAALAAESVGIDLVEVSPDDFGADDVDDAGAQGDAELEPMEAALREIAAGSDVDLAGVTAGAVESEFQTSRIQAMCDRLGIDLFAPLWQRDPVELAEAMFDAGFEIRIVQVAAYGLDESWLGRRYDADALDDLLALREEYGVHPLGEGGEFETYVVDGPHMDRRIDLTYDAVWEGDRGHVEIRDAQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ4</accession>
    <name>V6DUQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5010" checksum="BB06888383B42942" modified="2014-02-19" version="1">MGHVRIQTCWITEDGRRTDGDVATPGRRADSGTDSQTLNAVTEYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ5</accession>
    <name>V6DUQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-ubiquinone oxidoreductase chain 49kDa</fullName>
            <ecNumber evidence="7">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_02691</name>
        <name evidence="7" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077444.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4328at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="5">
        <location>
            <begin position="42"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="6">
        <location>
            <begin position="304"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="554" mass="63109" checksum="8C97D7E58A00224B" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ6</accession>
    <name>V6DUQ6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C464_02390</name>
        <name evidence="4" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="3">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="226" mass="24079" checksum="C4E8F740738900C1" modified="2014-02-19" version="1">MGLSSSAAVVDLLQIPMPGESVITALGAVAILLLVGLSAFFSSSEIAMFSLPQHRIDSLVDEGVTGAKTIRDMKQNPHRLLVTILVGNNIVNVAMTSIATALFGIYLSGGQAVLATTFGITTLVLIFGESAPKSYAVENTESWALRIARPLKLSEYALYPLVVLFDYIVKGVNSIIGGSAAIESTYVTRDEIQDIIETGNGRGSSRRRNARCSTASSDLTTPSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ7</accession>
    <name>V6DUQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_10374</name>
        <name evidence="6" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077469.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92826at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="232" mass="23705" checksum="38E318A791C4B855" modified="2014-02-19" version="1">MSSFVTLGAGVVFGLALAAPPGPMNAVIAEESVLRGRLAGVRAGLGAATADAIFFVLAYVGVVAVVESFPLLQGFMVAVGGVLMLYFAVDAARGARASFRPTESEEPVVAEGKGFRKALVLALTNPYQVLFWLTIGVGLLQPGELDVLARLPVVGADLAGTFVVATGSPALIVGFFLGVLLWVTGFPTGLVAAERRIETFAPVVAVGSAVVLAGFGVYFLYDAATTLSALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ8</accession>
    <name>V6DUQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase/carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05000</name>
        <name evidence="2" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11777" checksum="067343C32F896204" modified="2014-02-19" version="1">MTDVPLEHVHVAPDDGTDGEPAPAVFVLHGRGADEEDLLPVAAELPDELHVISLRAPDPLQGGYTWYELDLSPADWNRASRRRRLPAEPRPDRRERRGGGRRLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUQ9</accession>
    <name>V6DUQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_13417</name>
        <name evidence="2" type="ORF">BN903_247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076690.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113016at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045940">
        <property type="entry name" value="DUF6360"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19887">
        <property type="entry name" value="DUF6360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="11089" checksum="E3EEF55FB0A47235" modified="2014-02-19" version="1">MSNRLLRVNAYTTLDFVDGRVRAHEFETEAPGVVNVTAPREDPEHVSLQVELDGTAVDDLPAHAEEFDLSPAQARELADALNDTADRVEAARRGSSADGDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS0</accession>
    <name>V6DUS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein-tyrosine phosphatase, low molecular weight</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_04081</name>
        <name evidence="3" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076985.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108917at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="2">
        <location>
            <begin position="17"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="16717" checksum="AFB5A9079CEB03EB" modified="2014-02-19" version="1">MTSTDTADDETATDETTILTFMCVRNAGRSQMATAFAERERDRRGLGDRVEIRTGGTDPAESVHEVVVEALAEVGLDANGRTPQAISDAALAESDFVATMGCSTLDLETVDTDDWALDDPGEQPIEAVREIRDEIERRVIAVFDERFGEFDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS1</accession>
    <name>V6DUS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_15261</name>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077453.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6020" checksum="C606BEC59177C0E0" modified="2014-02-19" version="1">MSEGSIESDKEVGVALALGAIAVVGAVVMFAYPGQLGKAWGFAAAFVFATLAVGAVQLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS6</accession>
    <name>V6DUS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_10249</name>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="122" mass="13847" checksum="3A9EC888FC2364E7" modified="2014-02-19" version="1">METSDDEYEVGEPVPFRVTLRNRLPVPISIPTVSPLLWEWTVDGNVEAAEVPIRDPPDEEGQLSFDRGERKEFQKRWDQLFRVSDSEWEPAGVGTHTIGVAINATDAEKRGLTDETTVRIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS7</accession>
    <name>V6DUS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase domain-containing protein</fullName>
            <ecNumber evidence="10">1.3.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C463_01326</name>
        <name evidence="10" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="10"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077430.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36092at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="9">
        <location>
            <begin position="13"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="8">
        <location>
            <begin position="127"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="7">
        <location>
            <begin position="249"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK39901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="402" mass="44038" checksum="FDA9477A36E7F71E" modified="2014-02-19" version="1">MLDYVGLEADLDEEARLIRDTARRFVDEQVRPEIGDHFQAGTFPTELIPEMGELGFYGSNLDGYGLPNVSETAYGLLMQELEACDSGLRSMASVQGALVMYPIHAYGSDEQKERWLPDLGTGEAVGCFGLTEPDHGSDPSAMETRAEREPRSGSDRSGTAAERDGDGYVLNGSKTWITNAPIADVAVVWARETSAEGSPVRGFLVETDRDGVTTNEIDDKLSLRASITGEISLQNVYVPEENVLPGVSGMKGPLSCLTQARYGIAWGAVGAARDCFEQAREYALDRDQFGGPIARFQLQQEKLAEMATQITTSQLLAHRLAELKERGDLTPQHVSMAKRNNVRMARDQSRIAREMLGGNGITTDYSPMRHMANFETVYTYEGTHDIHTLVLGEDLTGIAAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS8</accession>
    <name>V6DUS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4715" checksum="0F3963FC95830438" modified="2014-02-19" version="1">MCLRLPRRSGRGGRTAASPGRPGDGGGTGVGEATDTFDTVRPVWSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUS9</accession>
    <name>V6DUS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
            <ecNumber evidence="3">1.8.5.1</ecNumber>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_10479</name>
        <name evidence="3" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.1" evidence="3"/>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077483.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35759at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045174">
        <property type="term" value="F:glutathione dehydrogenase (ascorbate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="PTHR32419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="175"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="343" mass="39067" checksum="20938E4B503DE585" modified="2014-02-19" version="1">MNQLVNGEWRTDTYETTNEEGAFERGETTFRNWVAGSDVPEHVDAEPDERFQPEAGRYHLYVSYACPWAHRTLLARSLLGLEDAISVSVVDPWRGEGGWQFSPEKDGCTRDHLHDSDYLRELYVEADPDATCRVTVPVLWDTEEETIVNNESREILRMLSTAFDDLGNGASLLPDEGDDATVADVDEVITDIYEPINNGVYRAGFATSQAAYDDAIDDLFDALDRYDDRLADRRYLVGDSLTEADICMFTTLIRFDQVYHTHFMCNRQFIHQYDNLWPYLRDLYQTEGVAETVNMSHIKEHYYTTHPDVTPTGIIARGPDLDFEASHDRDRLAGAPPTPTADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV07</accession>
    <name>V6DV07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HVO_A0115</name>
        <name evidence="1" type="ORF">BN903_134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077034.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95496at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045397">
        <property type="entry name" value="DUF6516"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20126">
        <property type="entry name" value="DUF6516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="12013" checksum="CE533526AEA91587" modified="2014-02-19" version="1">MPATVVYRGENEKPDGSRYEMIAWQVPVTEDFPQGLKYSFQYMDADGDTLLRYDNSPYHLDIGRHHRHPPDGEITKLEFEGLSDLINEFQTEVHEIYEQRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV10</accession>
    <name>V6DV10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="3753" checksum="47BB4425C6D8ACE3" modified="2014-02-19" version="1">MARISMSAVDIQHDPIAAVAVAESAPVGDGPSAGFIGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV11</accession>
    <name>V6DV11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase, IS605 OrfB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C496_06637</name>
        <name evidence="8" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076810.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18222at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="184"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="317"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="426" mass="48321" checksum="5A7D19CECA1E449F" modified="2014-02-19" version="1">MAKQVVTRTYTASIRNQSQVSDDLDALGFAASKLWNIGRWTCSRIWDEIGHIPNHTELTAYLKSHERYDDLHSQSSQRVLQELAEAFNGWYGKRRNGDTRANPPGYRKHNDDHPRSTVTFKAAGFKLDTQYNRVRLSQGSNLKEYWSDFILCAFQTRPDVDLSAVENVQQVKAVWTGDEWKLRFVCKVEVDVSESSGEQTVGIDLGINNFAALAYEDDHSELYPLNCLKQDDYYFSKRLARCDDSNSEQATRLNQKKSGRRTHYLHTLSKHIVQRCVEENVATIVVGDLSGIREDDETDASKDWGTHGNLDLHSWAFDRFTELLTYKAEMEGITVEKVSERDTSKSCSCCGRKRKANRVERGLYVCDNCGTTANADVNGAENIRQKVSPSSPNLSVNRSNGWLAQPSTFRFDKETGAFAPQEQVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV12</accession>
    <name>V6DV12_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C462_08015</name>
        <name evidence="6" type="ORF">BN903_139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077036.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58376at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="53"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="311"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="65"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="398" mass="44243" checksum="F0260C45DE3CDA6D" modified="2014-02-19" version="1">MTERGDIFETGEIFRERELVRVGHVPDLDRVVGRDEEIESIGSTLAPAIRGGPPETTIVYGKTGTGKSLVTRCVAREATRRATANGNTFAYAYIDCSDYGTEAQASRQMARELHERLGDAVDDRSIPRRGIGAADYRDITWELLTEGDVDSFVVVLDEIDKLDGDALLRSLSRAQESGKADTFVGAICISNKIEYREQLGERVDSSLQDNELVFDPYDATQIEAILTRRRDAFAEGVLNDGVIPKTAALAAREHGDARKAIDMLYEAGRLAEQEQADYVTEAHVDEAVDRAEINRFQKLVSGQTPHVKHILRALALLTEQTDTRTFRTAEVYDAYQRIAEQEGTTPLSYDRVQRLLKEQAFLGVTESKHTGGGHGEGSYRVHRLLRSPEIVTRGLDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV13</accession>
    <name>V6DV13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_03221</name>
        <name evidence="1" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077492.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116449at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9834" checksum="DF392F636F4AA211" modified="2014-02-19" version="1">MSVFDKFLAGFSFRGSTPDYAVGDTIEVMVTGTEGDGERGAAVARIGDSTLRIEDAPADAVNTRVLVDVTSWDETEHRGVGTYRKTVGESAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV14</accession>
    <name>V6DV14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06254</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077541.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="11161at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="48"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="458" mass="52037" checksum="9DF41F7C22F39E49" modified="2014-02-19" version="1">MTTQIKDPVHGYIELADPLVDRVIDTSAFQRLRHVKQLSATHLVYPAANHTRFEHSLGVYHLGRRVFENLREEPYFTRETSPETVDEIQSTLECACLLHDVGHPPFSHVCERFFDPAELRDRLAEEGFVASLREAGLGDAPVREASPHELVSCLLILDRFADALRSLSVDPEEVCAYVLGYSLVYERGGPWQHGLGAQLLHSPVDVDRLDYISRDNWMTGANVLNFDTDRMVDAYTAHPDEGLALSEKALSTLGNYLEGRIALYMWVTQHHKSVYANALLRDLTERAAALTGDPPVTIDGVIEDEIDDNTVAERLRRLARDRPETTFATLYDRYRARRFPTTCWKHRIAYADRVDVDREAFGEWLVSGDDRLERALADELGVPAHDVWIERSYVPEYEPSELADIPIAYGGTTRSAGDWGLYGERTFDSPIPFVYVPDGERKRATRWLVDRFRAEYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV16</accession>
    <name>V6DV16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5064" checksum="5FAFFB80F2E443D9" modified="2014-02-19" version="1">MGAAAAGRSFTGASFDSTASKLTNVTRIVARVLVKNIYLGAHSPTVLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV17</accession>
    <name>V6DV17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transport protein (Putative sodium-dependent antiporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sdt</name>
        <name evidence="3" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076814.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78231at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="325" mass="33684" checksum="10CECF0FB5E9B9E6" modified="2014-02-19" version="1">MGVSSGISRAAQVATKYFVVWVIAAAGLALTYPNTFVPVLDYVNPLLGIIMLGMGLTLQPEDFQRLVKRPIDVGIGAVTQWLVMPLAAYGLYLLFDLPDAIGVGLILVGAAPGGTASNVMTYLGRGDVALSVAITTVTTLAAPIVMPAWTLFILGEAIDVTFIEMFTSIVQIVIIPVVLGFGIRYVLDRYSPTAAEIGVDIFPVISVVAIVAIVAGVVGANIDNILTAGALVLAAVVLHNGIGLGAGYGVGTAFGMSKDRVRTTTFEVGLQNSGLAVALAASLFDPAAALIPALFSVWHNVTGPALASYFTWSDDRLTSGSVTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV18</accession>
    <name>V6DV18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterio-opsin-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TP009.19</name>
        <name evidence="2" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077494.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126296at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8064" checksum="B6CA9953A3C4A871" modified="2014-02-19" version="1">MTDTNTEQPPVLRTRSVVGIAVCVVTAFVGIFLIPTLQEPGGGFNVRFWTMAALELLAMVGVVYFVLNLHEEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV19</accession>
    <name>V6DV19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5470" checksum="EAA99A9C1A3A24E9" modified="2014-02-19" version="1">MHHPGKPRMGRVRRTPRTHPGRFDDNRVYVRSRRPLNSSEFVERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV20</accession>
    <name>V6DV20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_11069</name>
        <name evidence="2" type="ORF">BN903_149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9967" checksum="D857BE7EEEBD80C4" modified="2014-02-19" version="1">MTGIGVLTEEGVFRGVPYVGAIALGGEPFWPVIGGTIAWAFLHGTGRGITLLVTTGWLSAGVWLVGHWEIMVGLHFTGNLFVAMWQVLDWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV21</accession>
    <name>V6DV21_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11909</name>
        <name evidence="2" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077559.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40873at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="54"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="451" mass="48864" checksum="0218E82660DB11BF" modified="2014-02-19" version="1">MTQTIVRNGTVVSLDPDVGTLDEADILIEDGEIVEVGGGLSASNAEEIDASGHIVVPGFVDSHIHLAQTQVRGIAGDWSLMNEYFDHMLGNITGLYRPEDMYLGGLFGAFEKLHTGTTTALDWSYPNTLEHGERAVDALKDSGLRAVYTYGPPGDDSAKWWYESDVGLPEENIRQLHEDQIREDDLLSLALGLRGPDFCTDETARGDLELARDLGALSTIHMGAALWPSSEYGGDYQGFGCLEDLLGPDVNVAHGNHFSQEDIDHAIEQGVSFSSTPEVEMQMGHGIPVTGKVLEAGGRPAWGVDVCSNVSGDMGSQMRIGMQLQRMFDNQAVLEGDEEVTEVSISARDTLEMATIEGAKALQLDDEIGTITPGKRADLVLFDANDFMTAPSHSPVQTVVFQSDPSHIDTVLVDGEVVKRDGELTNPKVREEFDRFVASGERLLDEAGIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV22</accession>
    <name>V6DV22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5785" checksum="D2B11DEE607807BE" modified="2014-02-19" version="1">MGAGIIFLLSLPVLADVMSPLGALSPTGLLILFLFAWLFLWLLIAVTRQRVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV23</accession>
    <name>V6DV23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_06024</name>
        <name evidence="7" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK39996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="97"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="36587" checksum="FD1F35869225A348" modified="2014-02-19" version="1">MSLLRYTLRRFAQAIPVLIGIVTITFFLANQIPGDPVEIMLGPTPAQEQVEAIRARYGLDRPIHVRYFTYLSGVLTGDLGLSIYYDRPVLEMIMLRLPVTLLLMLSAFAFAIVTAIPLGVLSAKRRNEPADHVSRIVSLIGVSTPSFWIGLVLIIVFAFYLGWFPARGLILPWANPADVRGAATQFEVLRQSVHHLFLPMIALGTLQMAQITRIERSSMVDSLQGEYVKLARAYGVPESTIVRKHAFQVAQLPVITIIGLGLSTALGGAVLTETVFEIQGMGRLIITAINNQDYELIMGTTLVFGFVYVIGVIVTDITYSYLDPRVTYGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV24</accession>
    <name>V6DV24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_07040</name>
        <name evidence="1" type="ORF">BN903_154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10087" checksum="1E7F5EFFA0FA06BB" modified="2014-02-19" version="1">MTDSNTLENLDAKHDRNREQRIAAIKRWVAYIQAEPPETWGPQQNAVVNGQISAAQHVATSAAHQKHVSDVAQDILAIQNDGSDTAGSQDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV26</accession>
    <name>V6DV26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP-binding HSR1-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07425</name>
        <name evidence="2" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077596.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="65214544"/>
    <dbReference type="OrthoDB" id="61585at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="26"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="23619" checksum="853F07DBF56C519D" modified="2014-02-19" version="1">MGLLTNLRDSISRVTDGLFAADEPKRIGIYGPPNAGKTTLANRIARDWTGDAVGPESHIPHETRRARRKEGVEIERNGRTVTIDIVDTPGVTTKVDYKEFLDHDMEKDDAVRRSREATEGVAEAMHWLREDVDGVIYVLDSTTDPFTQVNTMLIGIIESQDLPALILANKTDLPGSDVQQIANAFPQHETIPLSALEGDNMDEVYTKIAEYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV27</accession>
    <name>V6DV27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleic acid binding OB-fold tRNA/helicase-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_2973</name>
        <name evidence="2" type="ORF">BN903_159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077044.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64051at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="282" mass="31399" checksum="606B9157DACE2E33" modified="2014-02-19" version="1">MSNTNVSTKEVSVDEQGLEPAETEPDAEPLRPRVELQTQAKVDANHPDAGLRGLSLAAEEKALAREAEKARTRERWDRRQSSDREARTRQVAAEGSRQRRDRFAERRASVASWADPERDDPRATLSQDELATVNQEARRIATNTTGWTPAAVSRQLARRVADGESVTTAVIGVTEQIQQAPGTIIPIDTVSEVGRGTVSIAGTWSEDWDPAHPAIQQVGLLADDTGRIKVTVWQKSDQPRINEGEQVRLVDVAMSWYDGRVSVALTGWSRVDFPERDRWWDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV28</accession>
    <name>V6DV28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C435_16820</name>
        <name evidence="7" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076819.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="262"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="338"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="387"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="460"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="579"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="637"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="845" mass="94416" checksum="EC5088E2DF5A390A" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV29</accession>
    <name>V6DV29_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">ahcY</name>
        <name evidence="7" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077524.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17629at2157"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="6">
        <location>
            <begin position="194"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="223"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="302"/>
            <end position="304"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="429" mass="46564" checksum="A8F439083AEC83FA" modified="2014-02-19" version="1">MSETAYPPVSKHLSDVETAREEGRRKMDWALQHMPILNALREEFADEQPLAGETIAMAMHVEAKTANLVELLAEGGAEVAITGCNPLSTHDDVSAALDTHESITSYAVRGVDDEEYYDAMHACIAHEPTITVDDGMDMVKLVHEEYPDLIDSIVGGAEETTTGVDRLRAMDADGELHYPVFAVNDTPMKQLFDNVHGTGESSLATIAMTTNLSWAGKNVVVGGFGQCGKGVAKKASGQNANVIVCEVDPRKALEAHMEGYEVLPMVEAAKKGDVFITTTGNRDVITREHFEEMNDGVLLANAGHFDVEVNLDHLDDLAVDRYEVRDGVEGFEMEDGRVLNVIAEGRLVNLAAPIALGHPVEVMDQSFGVQAVVVRELAANGESYDAGVHDVPDGLDREVADIKLAAEGVEYDDLTDEQREYMGSWEHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV40</accession>
    <name>V6DV40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal peptidase I-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_11946</name>
        <name evidence="3" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="273" mass="28472" checksum="4934D297B165F1FF" modified="2014-02-19" version="1">MDEGDRSTDADESAGRDERTRDGAEKDRGGSPDESKEEAPDESKGEAPDESSDESASENVDDEGGAGPAAGGDSVAEPDISGGERSDAEHASEPVADADGTEIGGESVEVEGAVGADGSAGRSGGRSESGRSPESERLAESEDFSESRDPSERSERPGAGEEESLLYRFRHDRDGALMWIREMLSSVAVVLLVGLLLFGVSGIWXXXXXXXGTSPRSSTRYYGGTNLGVGGLASRLLARGEGRRRRGRRDRGAAAPKVSSSRPSTTTRGRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV41</accession>
    <name>V6DV41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11799</name>
        <name evidence="2" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077576.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69792at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043868">
        <property type="entry name" value="DUF5828"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19146">
        <property type="entry name" value="DUF5828"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="228" mass="25330" checksum="94D82C2C5526917C" modified="2014-02-19" version="1">MEESISGFKMRGDWGDVVEHGERVALALREVGVDGGPYYEFDEWRPKTHERIDEDVSEKTAAQASVDEGKGERAGKSPGDDLQTAGEKLTESYEQVEENDTESARESWGESIEHVARAADSASRKALRKVEDAVYRNVMTQMAPYYFDNELVSANIQEVARAEDGETFVFEVNVNDDELKDEVSAVLGDYESEIDRWHVDTEKRTEDVAAAEGVEPPAEEGGPDSTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV48</accession>
    <name>V6DV48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mandelate racemase/muconate lactonizing protein</fullName>
            <ecNumber evidence="2">5.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hmuk_0941</name>
        <name evidence="2" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076829.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38489at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018849">
        <property type="term" value="F:muconate cycloisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="164"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="388" mass="42341" checksum="E61323B2951DF241" modified="2014-02-19" version="1">MEITGVTATTVDVPLVDLDEPLGIGPYVTNHGQVDSMERVIVEVKTDEGISGWGEMRTFLTADATESVIEDGIGPLIEGQSPFEVERLRRQVFIEYTNVELFFAAVETACWDIAGKALGKPVYELLGGSTAPEQTTAMNADAADHEFGPDRDIEFAFCLGILSPAESRAKAQEALDAGFSVLKTKAGRDWQQDVARIEAMHDEVDGALEFRLDPNQGWSLDQAVRVGAALEDSGIYLQYMEQPIRVNAHNSLATLRKRLRQPIAPNEDTYIPNNLRSLADAGAMDVAVLDLTPAGGISGLRQQASIVEDAGVPFTHHCAFDLGIRTAAILQSVHGIPGFSLPPDTTYYAWQDDIIADPFEVTEGHMRVPEEPGLGIEIDREMIDQYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV49</accession>
    <name>V6DV49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NifU domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07679</name>
        <name evidence="3" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077536.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103746at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="2">
        <location>
            <begin position="22"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="11811" checksum="A02F77537A4E63B3" modified="2014-02-19" version="1">MSDESDESLADRVERWMVGQMPIIQMHGGTSVVREADPDTGEVVVELGGTCSGCGISNITADNIRRDLILDFDEVDDVTVRTASSGDNGASTVEGGRGGELKHETESANHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYV2</accession>
    <name>V6DYV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_10268</name>
        <name evidence="1" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077932.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129602at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009923">
        <property type="entry name" value="Dodecin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025543">
        <property type="entry name" value="Dodecin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036694">
        <property type="entry name" value="Dodecin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39324">
        <property type="entry name" value="PTHR39324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07311">
        <property type="entry name" value="Dodecin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89807">
        <property type="entry name" value="SSF89807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7420" checksum="FB5ED075450D6671" modified="2014-02-19" version="1">MVFKKITLIGTSEESFDAAADEAIDRAEDTLENVYWAEVEEFGVELQGDADREYQAEVEVAFELEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYV3</accession>
    <name>V6DYV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallopeptidase M24 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05372</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="2"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6918" checksum="1FB9968B238D6952" modified="2014-02-19" version="1">MSLHESPSLSGPGELRPGHVVTIEPGVYDPEVGGVRLEDLILVTDEGYELLAEYPFGVVPQARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYV4</accession>
    <name>V6DYV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10561</name>
        <name evidence="2" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077937.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="85146at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20829" checksum="6AF0A69BCB69574D" modified="2014-02-19" version="1">MDDPDDPADLAWETLDSAVDYACPGFDVRRDEVRFPDGETDGFHYVDEPPAVVVLPLTPDGDVVVIDEWRQAVGRVNRGIPAGTMEPEDGDEEAGIERAAARELAEETGYEADAFERLTTVEPTNGMANAVHHHVLATGCEPTADRDLDHNESIAVETIPYDDLLAAVVDDGLRDGRAVTAVLWYELLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYV6</accession>
    <name>V6DYV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_10283</name>
        <name evidence="1" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077930.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113137at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043854">
        <property type="entry name" value="DUF5816"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19133">
        <property type="entry name" value="DUF5816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9032" checksum="8C1EC8E2F2367A2E" modified="2014-02-19" version="1">MSLKATTTPSGERVYTDRSRVERGADGPFYVVFADETGESRWGFRCGNCGSFDTAMDTMGRIQCTECGNLRKPDEWDAAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYV7</accession>
    <name>V6DYV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_05392</name>
        <name evidence="3" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078397.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128202at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="12096" checksum="A737237D5D914CFE" modified="2014-02-19" version="1">MPSNEHTGLVAALVAVGVVVPLYAGAVSRQLLPGLGVGLSALVTAALVARDGTGRRTLARATIAVTIVYGAFTFQLLVAVVAACAVYLSAWLTGSDSPLGAPDTEIVPVEPPAAEDAGAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYX0</accession>
    <name>V6DYX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="4942" checksum="7FC3E79E6F5FCF9E" modified="2014-02-19" version="1">MGVHTLCSDGSPTRRDSAADGRGRDNSSPGNARFGRFLGPRPVVTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYX1</accession>
    <name>V6DYX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3639" checksum="FF055789C5DBA514" modified="2014-02-19" version="1">MLATGGNGKRERTAPSGAAGPGRSRKAVGAAKRGSADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYX2</accession>
    <name>V6DYX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hqrw_3750</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5797" checksum="18CC7C3A5452A77C" modified="2014-02-19" version="1">MVHLRSIRTAIVGLALAVLTTGLIISGDSLDFPFLIFSLFVCLYAFVPPFIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYX5</accession>
    <name>V6DYX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">C472_12655</name>
        <name evidence="14" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">AJ67</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the halobacterial S-layer protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334956.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93516at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011635">
        <property type="entry name" value="CARDB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026371">
        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026452">
        <property type="entry name" value="Surf_glycop_sig_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07705">
        <property type="entry name" value="CARDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04207">
        <property type="entry name" value="halo_sig_pep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0134">Cell wall</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0701">S-layer</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="CARDB" evidence="13">
        <location>
            <begin position="813"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="870"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="888"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="908"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CDK40570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="961" mass="100094" checksum="42E41A390F9D59B3" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYX7</accession>
    <name>V6DYX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_06850</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040087">
        <property type="entry name" value="MJ0021-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43288:SF1">
        <property type="entry name" value="PTHR43288:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="198" mass="22620" checksum="561DD955D67FCC82" modified="2014-02-19" version="1">MHGSEWEEILHIAREEGLTPAFEIPGIRAEPEFLEFLDEGAAEFCNINEFEMSDGNYRRMQEEGFELQEGHMSAVEGSKDDAILEEMASHEKVYFCTSVFKDAAQHRNRLKRMAKNIRREFDEVTDDGTLVYGKAFADAERFEALGVPEEFYTAKSNHVEVAWWLLEEMVEDGDLAEGEIVEQYPTVDGTVVERTPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYX8</accession>
    <name>V6DYX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein AU-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aubA</name>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007295">
        <property type="entry name" value="DUF402"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035930">
        <property type="entry name" value="FomD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04167">
        <property type="entry name" value="DUF402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159234">
        <property type="entry name" value="SSF159234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF402" evidence="1">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="12208" checksum="8668E1C82B48540D" modified="2014-02-19" version="1">MTGGGTYDGLGVDREAGDVAETSLKEGRWWYPTTYRGRDGTVRGTYVNVCTPVEVFPDAARYVDLHVDVVKRPDGTVERVDDDALDESVAAGYTPEPLAEKARSVASALENAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYY0</accession>
    <name>V6DYY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="10286" checksum="140D822C368F0BC5" modified="2014-02-19" version="1">MATTAVGTYRIGVTPERNDPQKTAETTRRTPLPHSLARDGREGDRPHARKVSPSRRVVRADRPRSDADEPVSGRRRRRRTRSSRRGRARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYY2</accession>
    <name>V6DYY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000029">
        <property type="protein sequence ID" value="CDK41076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4324" checksum="8C8B5F6E26ED1DB9" modified="2014-02-19" version="1">MSTRTAIGASALVDAERADGNASLSKALSTQRRLHRTSSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYY3</accession>
    <name>V6DYY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_08844</name>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077967.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83907at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16910" checksum="BA7DF4A9A4DFB559" modified="2014-02-19" version="1">MPTNSEVEMSPAEVDALLSRHETGVLALARDDAPYAIPISYGYDADDRALYLRLVSTPDSEKREFLASTPQARVVVYEDDDGEYASVVGVGPLERVDLDELTPETIAQYGEARRPLFEIWADDKPDLDIELYRFAPETLTGRTVVVERDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYY6</accession>
    <name>V6DYY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">L-lactate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C472_09106</name>
        <name evidence="9" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077971.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="11401at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015129">
        <property type="term" value="F:lactate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003804">
        <property type="entry name" value="Lactate_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30003">
        <property type="entry name" value="PTHR30003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02652">
        <property type="entry name" value="Lactate_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="588" mass="61463" checksum="03D1C5EAAD984E99" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYY7</accession>
    <name>V6DYY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamyl-tRNA reductase</fullName>
            <ecNumber evidence="3">1.2.1.70</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hemA</name>
        <name evidence="3" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000030">
        <property type="protein sequence ID" value="CDK41081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033014">
        <property type="term" value="P:tetrapyrrole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_dimer" evidence="2">
        <location>
            <begin position="26"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="17944" checksum="1A1F68F588B45051" modified="2014-02-19" version="1">MTVYDIDDLEDVTRRTRESREQEAREVESIIDEELARILKAYKRKRADDAISSMYAGADQVKARELDRAMSKLEAQGDLTEAQRETVEDLADALVGQLLAAPTRSLRDAAGEDDWETIRTALRLFDPEFTPEADEAAESDAPDAGIGSPDAIPDSVAEELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYY9</accession>
    <name>V6DYY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipid/cholesterol transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_09126</name>
        <name evidence="3" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="216" mass="23376" checksum="1A5965A78120C20E" modified="2014-02-19" version="1">MRLGERIEAGIRRLNDVIVDRPRAVVVAFLLLTAVFAGGIGLVSTETEPTEGFTEGLDEQEALDAVNEEFEDPFAANGESTQLIHVSGNALSKEALVRNLRVLERVESRESLRMADANGAATTVAQATDPSATTVTXXXXXXXPDRTRSTVGTGVRLASVRAIRRVGSFAFVREDGRESALAGDRAREGILLGRPRSRPIRRSRGAMPVRPARHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ70</accession>
    <name>V6DZ70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5970" checksum="7002C21242F9AF6B" modified="2014-02-19" version="1">MIALVVKAEKYSPDHDCSLDLDIISNWHISTVLNIPIDYTPFHIYYYLTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ71</accession>
    <name>V6DZ71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halxa_0033</name>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078059.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="134793at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20496" checksum="9D933D50FC70E444" modified="2014-02-19" version="1">MSDDPANGTTEVVELDDLAESIQSGQDIIESVEDDIPANALVALETVEDDVEGLEDTVEHVDGTLPSDFEADVQATQDDVNDLQEALTTGGVDPNLFRKVEDLEDTIETIEDRAVDARDQYGVKVDNAPVEFFDEATPTAESILSRFGKNTDDALVEVGTENTYSGTDEVDLSDPGVERFTSQPRTPGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ74</accession>
    <name>V6DZ74_9EURY</name>
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        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">uspA30</name>
        <name evidence="2" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078061.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="153"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="289" mass="31021" checksum="A30FAC8B8C5316FF" modified="2014-02-19" version="1">MFDQILLPVDDSDTSQRAQQYAQVLANAFDAEIHALFVLENGGLSDGDGDGSVSERLDSELRTTAESTLETVVAACESDNIAVRTSITSGHPTEAILDYSDANDVDLVVLGAHSRGRLVRFLRESIAEQVAQNASIPVLTVRSQEEEVAPEIQDILVAIDGSESAQHASTYAFSLANAFDATVHGLYVIESRFGNSGALRDLLERESESVLQAARAHAAQADVNLVPVTREGKPEREISEYATSQGVDLVVLGTHGRSGLDRFVMGSVATSVMRKANQPVLTVRSPLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ75</accession>
    <name>V6DZ75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5933" checksum="B382944B378CD00D" modified="2014-02-19" version="1">MGDLGALREAVDVVVEAVNKAGYELLARERYSIEIDELSGTHQCIWLWRDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ90</accession>
    <name>V6DZ90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_00597</name>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078041.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126322at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="12648" checksum="6B117775100CCCA3" modified="2014-02-19" version="1">MGRTNPTYRDALRAIEERWTEFRRALRRRDQPRFDRLFEYAREHADASGLLNHQNPLLPALLSIDLEQETKLEDHEERLEELEQRISDAEPDRQQPPEEGRTGEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ94</accession>
    <name>V6DZ94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4313" checksum="23609EF70A74BD91" modified="2014-02-19" version="1">MESAYLNTTRVTVPLNRVRGVIYDRGMMGTDTEHVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ95</accession>
    <name>V6DZ95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3862" checksum="F5F5AB32C8A504E2" modified="2014-02-19" version="1">MVHLGVAMLDFSRDEPGAKDTSITDHLSVGSCCPGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ98</accession>
    <name>V6DZ98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C496_23558</name>
        <name evidence="1" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="368" mass="41741" checksum="20042E1C2927BE85" modified="2014-02-19" version="1">MPFLALHDGTEVIPNQVQKGDFLECPKCGDQLKIRDSHRRKGSFVAQHFYHAAEEETGCGGESPPHLRMKSIAYSKLTTEYPDATIGLEQQLGDRRADILVEFLQPRFPEGRGIGVEVQHKHEDKDVDAVTAEYLAAEYSVLWLGERDFSGFNVDLSGILPTWPHAIQHDFSDGYHGVIYWLRQPKPANPSIDVFLPREYLAEHSEDLRRAWEYGKFDQGGQSDWNDLGFWWLSASYDPYQKWFKLTETPDGRTMLQLGKQVRGTEYVLAPVQIEHSRNRGRVHSLAYEVESADTSAGEWADIEKAWLETGLQSTSVIFKLVATPSGELALSLGKYKEHSDDGEFITVSTEFQRNLKESLHELANLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQA4</accession>
    <name>V6DQA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_00442</name>
        <name evidence="3" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="150"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="289" mass="29741" checksum="32AD1B9BC4FEC9F7" modified="2014-02-19" version="1">MSPSAGLAVAVAAVSAGATLVRLSDAPSSVAAFYRVLFTTLPLASVAAWRYRGEFARIRSRDLAFAALSGVALAVHFAAWFESLRWTSVAASVTLVQAQPVFVALGAWLLLRERVTRRMAAGIAVAVVGMASMSLGDLLGGVAIGPRPLYGNALALSGAVAAAGYVLAGRSLRQRISLIPYVTVVYGVCVVVLLAFVLAAGRPLTGYPLREWLLFVGLAVGPGLLGHTVLNWALAHLESSVVSVSLLGEPVGATLLAFALLSEAPTPATVSGGCIVLFGIYVTAAADPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQA5</accession>
    <name>V6DQA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NJ7G_3221</name>
        <name evidence="1" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076243.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115415at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="260" mass="30183" checksum="36677A3215A8A02C" modified="2014-02-19" version="1">MDINYLIDHFNDDAGHKEEVALIIYYIENRSENEIEGVKQVEVKNVIRNSRSRVSTSSVSTYFSRLDDAGWISEANGDRYILTHDGEDDVEELLADGALNTPRNKHERFIDSEIFEEDRYQNLVGDVNESYRQHIYDGTMVLTRKFFENLIFEILRGEYSGKDTQMFFDQENQRHYSFDELLNNLKIGVPDLKRFTKEGLDREMVEDIRDLKEKGNKGAHSIRVEFEEGEVEALSDDATQLAEVIYEVWKGVQNSNGSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQB0</accession>
    <name>V6DQB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="10272" checksum="44EF11238FAA357D" modified="2014-02-19" version="1">MTPCRWRPLRSCGRCADGFRGVDSERRRRIPRADNIALAALTLTCVTSVPGLHWRRLRLLIHLLRWHDRLVSMSLVHYPWRIYQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQB1</accession>
    <name>V6DQB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
            <ecNumber evidence="5">3.5.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C463_11202</name>
        <name evidence="5" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="13880" checksum="E057997B6B1084D2" modified="2014-02-19" version="1">MIVGARTGSEAEWDRAADADVEVVSPEDARAWIDALDGDGSGDGHGGPFDADGSVYCSVDIDALDPAYAPGTGTMEPFGLDPREVRDLVRAVAPRADGFDIVEVNDRDDGQAAALGGKLLREFVFSHADTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQB2</accession>
    <name>V6DQB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MA_1621</name>
        <name evidence="1" type="ORF">BN903_21</name>
        <name evidence="2" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11890" checksum="C77C194B1FED34AC" modified="2014-02-19" version="1">MFSLLRGCLRCSQRISDPCYSGFDAIRTDSSYGVVTLFHAPFQETSDELSRFGCQPEHHIGPKDLRFGLCRVYSRLLTTSRLRSFPALTEMFQFRAFPIARGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQC7</accession>
    <name>V6DQC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GntR family transcriptional regulator protein</fullName>
            <ecNumber evidence="4">2.6.1.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C463_12687</name>
        <name evidence="4" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.39" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076259.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51060at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="73"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="411" mass="45399" checksum="7C3BC196EFC8E82E" modified="2014-02-19" version="1">MSERDQSNDLSHLFTETVQETMDSSVYGAWRGIRDSGAVPLAFGFPYPDSFPNDKLVSAADSLFEIEGDRALQYAGGEYADALPELIVDQARDRGMDCTTDEIHLTNGATNAIDTVCQTFLDPGDTVIVEAPTFMGALRLFRNYGVDIDDVEMDEAGLDIEALAADLAVREAAGDPLPKLLYTIPNFHNPTGVTLTEERRERLIELAVRYDFLILEDDPYGQLRYDGAEPLPIRALDETGRTIRVNTFSKTIAPGVRTGWIVAEESFVKQFDRINAGGEPSFTRGLITRYAEDGRLDRAIEELSAGYRKRRDRMLESLEERMPPGTTWSEPNGGFFVWVEFPDGVDAERMLSGAIDEGVTYLPGSFFYTTDTGTRNARLSFSHASPAEIDEGIAALAATVRAEISRAEADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQC8</accession>
    <name>V6DQC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00080</name>
        <name evidence="2" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020017">
        <property type="entry name" value="XapX_domain"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03510">
        <property type="entry name" value="XapX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="7823" checksum="72C07076DC3BFD33" modified="2014-02-19" version="1">MNERRRRDGMSSTPILTVAALLVGVTVGALFAFLRVPIPAPPELPGVVAIVGIYLGFKIVGYAGVGFDLLDALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQD0</accession>
    <name>V6DQD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4562" checksum="2D909B14A2EA9DC2" modified="2014-02-19" version="1">MLWWSNTVVASVSVAASVRSFIYLRCCRSNQQVCTRSHSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQD1</accession>
    <name>V6DQD1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">bPH_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_06764</name>
        <name evidence="4" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076263.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92108at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="23231" checksum="65029A58537F57F1" modified="2014-02-19" version="1">MSDSALQDEPTTSSENTAGLDLGWLSLEDGEEIRWASTPHKYSIVPALVVGLPLSVVLIGIPLIAASYLQYTNTNYVVTNKGLYSKRGILSRDVQQIGFDKVQNISYSQSAIGSSLGYGSVDVSTAGGSGVELQFRSILNPAAVQELISKEIDKRQQRDSAGTAETDDVLDQILVELRAIRSAVADDEEQVTNGSSSSADAEASPNRPSDGTVDHPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQD4</accession>
    <name>V6DQD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_06774</name>
        <name evidence="1" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="14990" checksum="58C9834BB225A561" modified="2014-02-19" version="1">MDDGTSLQSAADSADGNQFVQCAACESALRSPGRGNLSFLLLDQLTIPLVGCDDHLEEFRSLCGLATESRAELLDHHPAGGVNCPSCRHAPHQPQRVIPVGNGGLAVLACETHQSDILSRFSTGLQVRQHLTSSLDGTSTDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQD5</accession>
    <name>V6DQD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonine synthase</fullName>
            <ecNumber evidence="2">4.2.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01432</name>
        <name evidence="2" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076266.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16594at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="1">
        <location>
            <begin position="74"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="399" mass="41673" checksum="0C8ED569F3947BB3" modified="2014-02-19" version="1">MDRLVCYDCGASYSFGTAARCTCGEPLWFETDDEAVSWPGADPGSTDAVSYGHDSLWRYESVLPAVAPVGLAAAAGGTPLLRTPSIETADGPRVHLKLEGTNPTGSFKDRGTAVGIGRVDGPVGTVSHGNMALSVAAHAAATDREAVILVAEDTPDSRLAMIAQHDPHLFRVRGDYGRLYYDTLEGDFGVTFLNSDSPLQVAGQKTVAYEICEAFRPEVPDAIVLPVSSGGQASGVWKALRELDSAGLIADLPRIYLAQAARCDPIAQAYRRGASRVDPVTDEPTAAVSINNADPPSGNRALAAVHDTNGAVLSIAEETLLAETKRLASDAGIAVEPSCAVATAAVQELSESTELGSDEDVAVVVTGSGYKYESPETESTAVREIDRGDVPAAVRDLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQD7</accession>
    <name>V6DQD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate uptake regulator, PhoU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00055</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076218.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38423at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="332" mass="36582" checksum="7E30E8290993DC27" modified="2014-02-19" version="1">METRKVQVTGGSTYTVSIPKTWATANDVEAGTEIEFHPDGDSLFLTPRSEAERTRGTLDITDLSGQALRRAVTTMYVSGFDVIELEAAEISTEQRSTIRDAVQSLVGLEVLEETRDRVVVQDLLDSSELSIHNAVTRMRLISLSMLEDAIAALAEREHDLARDVIGRDDDLDRLWLVVSRIFRATLRTPKAAEELGLPREECFDYHSSARQLERIGDHATKIAHLTLNIDDPLPDEVVEAVSDLHGDAVDVIDAAMDALFDDDTEAATRRANEARTGVRAIDERVRAIDELLRELDPTRAQLLGLVVDSVLRSADYGGNIAETALQKAAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQD9</accession>
    <name>V6DQD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10965" checksum="320E10415AD4FCC4" modified="2014-02-19" version="1">MRGSSPRSGGRCAGCPDARGRRIEGQTISGYAFQQASIDWPASRARESVRAIDGEGPDTEHSSPWVREWTSCDGQVRGSPIDRRVASRRTAISHPVSTILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQE1</accession>
    <name>V6DQE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6963" checksum="7052339FA34B2919" modified="2014-02-19" version="1">MFVYNDIICLIPAYIRIKVEYIDSYGSEVSNREGSHPNGDEFREYRSYMGNNPCTCTNLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQE3</accession>
    <name>V6DQE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_06704</name>
        <name evidence="1" type="ORF">BN903_122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076269.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91126at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="179" mass="20368" checksum="54F24ED8ED8169EA" modified="2014-02-19" version="1">MTHELRFLERLRQRVASLLHAPLSLVGLYAERETPREQYAFTLRKPSPVVEAQLHRFSFVRNLVSSLKYRAYATPPETTVASWVRYPEGALASDDQLHLALYTGTDRATTDVYAHWEPSWIRHPIRHYRATGVDAQAGIERARSLFENAGIEYAVVPAEERIGVDADTTVPDDRSPPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQE4</accession>
    <name>V6DQE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5750" checksum="A72553DACD566211" modified="2014-02-19" version="1">MPRACRHPIAGAYRHRRFVDGSVRRRQGLLTERTRLSGSDLINTLTSRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQE6</accession>
    <name>V6DQE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00130</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="9862" checksum="FED91EDFBF6D76FD" modified="2014-02-19" version="1">MSAADGTLTDGSEATVDLPGNAPLKFNEPFEIRENTQTTFTADFAPVERGNGRYLLRPVPSGIEVAYGDAEDADESDGSDSSDDAESSGGNTSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQG0</accession>
    <name>V6DQG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C464_03110</name>
        <name evidence="4" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulator TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076233.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86536at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021586">
        <property type="entry name" value="Tscrpt_reg_TrmB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11495">
        <property type="entry name" value="Regulator_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="2">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Regulator_TrmB" evidence="3">
        <location>
            <begin position="110"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="350" mass="38668" checksum="5673670CF831B01A" modified="2014-02-19" version="1">MTDDLRDTLDRVGDRFNLGEYEIDAYLAVLEHGELTASDIADRTDIPQPRVYDTVRSLSDRGLVELRESRPMKIVAVDPEDAFGDLRSSFAEMVDELEARYTAPTRETEAVSLVKSRSTILRYLEEVIANAEYELAVSLTPGLLRRFRDELAAKVAAGVSVELLVTPASNAPDPTEFDYLEVATIARARRGITTPVLAVGDGEYSVYATQDALRDDRERYGVIFNRSALGFLVSGFFGTVLWTTAETLAADGEERPFPRRYASIRRAVKDVREFDGEEFYATVEGRDIETGEEVTVRGKVVDVAFVDTEEVASLVVDTENGRVEIGGRVAALEDVEGQEIVIGRGEPPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQG3</accession>
    <name>V6DQG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_00636</name>
        <name evidence="8" type="ORF">BN903_139</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076280.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58511at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="286" mass="30933" checksum="CE07A87C0C060CE4" modified="2014-02-19" version="1">MYLLQVDAITNAVDVAAIATTALRFVAGFVAVLLLGKYVLIPGLRRIVRSRGFDEAVLSLGTNVLNAVVWVAAIAIGFAVAGYGAFLSAFAVFGGAIALAVGFAAQDLLGNFVAGVFILKDKPFEVGDWIEWDGNSGRVEEIDLRVSRVRTFDNELVTVPNGDLANNAVTNPVAYDTLRQKFVFGIGYDDDIGEATDIIVEKAEEHEEILDDPGVSVRVTELGDSAVGLQSRWWIDDPDRGDFVRVRSEYVTAVKEAFDDAGIDMPYVHRQLTGSVEVLESVADDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQG4</accession>
    <name>V6DQG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_13764</name>
        <name evidence="2" type="ORF">BN903_137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12151" checksum="DDEC6C3BAB860A01" modified="2014-02-19" version="1">MSAARTTSMLALFGFGSLLALVAFHTFLAGVATRFFRLQLSTSWGSVVYTIVLTPLLLLVSTLVFTGALGVGTGIDIGSSTILLALLIALPLALGVAIDYLYVPSPEEYELPDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQG5</accession>
    <name>V6DQG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4242" checksum="916F73F447BB7B6D" modified="2014-02-19" version="1">MAAEPRDQFSCSDLSDRRSGLFQVYISGLISNVLLPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQG8</accession>
    <name>V6DQG8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_06537</name>
        <name evidence="7" type="ORF">BN903_142</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076282.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83329at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="14"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20152" checksum="2021787A47D2C702" modified="2014-02-19" version="1">MSGLAIEYGDHERVCEVVDRLTYCAEGVSVSFDGYDEAHVKGPGLYFAVIGDSDYGAYADPMGENRWPRDDCSSVFDEDAFAAAAESVSVAQDGGVVVAVDGEIESQMVRFRDLGTRDAETDLVDDVSYEPWMGSRHMSAIETSVRPEVVATVTLSEETGRVSVFRDGEADSTGREEIGGRWRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQG9</accession>
    <name>V6DQG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halxa_0312</name>
        <name evidence="2" type="ORF">BN903_144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="236" mass="26319" checksum="157C6142A38319B6" modified="2014-02-19" version="1">MGKSRQMEGSKTILGMLRESRDFVFACILNSALILGVVVFEWSLVEIAVIYLIEIAVINLLFFSVALFTPQSVDDLDGDSWDEEPTPIQPIALIPPVYRRNINYVLRKAIISAFILAVIMRPVVPGYDLDSGLSLSVGLAIAGTVFFQLSRVWRYFIVNRSYRDKSPADALAFAFRPVFELFLMLVFAVAPVSFVIIGTGTDLDSRAVWLLYLVPMGAIRAWIGSLDPQTDDFSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI8</accession>
    <name>V6DUI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4574" checksum="6FA397F9102F773B" modified="2014-02-19" version="1">MSLEGRARPQRSRETPTPSCAFQASLLSSNGLSVYKTRTMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI9</accession>
    <name>V6DUI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xaa-pro aminopeptidase</fullName>
            <ecNumber evidence="2">3.4.11.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04965</name>
        <name evidence="2" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="25"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="199" mass="21959" checksum="59AED3B1920AE917" modified="2014-02-19" version="1">MLDTLGDDYSVRVRGDGPVHAGYISGEETALPHGHTPNERLSEGDVLVTGATANVDGYRSELERTMFVGDYSDEQEHHFELMLEAQTLAIDALGPGVPVAEVDRVVWDYFEEQGVTELAQHHVGHNIGLGGHEPPYIDRGWGERYDGDDALMQPGHVYTIEPGLYTDEYGYRHSDTVAITESGTETLTNFPRDIDSNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ0</accession>
    <name>V6DUJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription initiation factor TFB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05357</name>
        <name evidence="2" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006628763.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125922at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIB" evidence="1">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="102" mass="11258" checksum="742E1933A30FE25E" modified="2014-02-19" version="1">MYRASDRVDNEAWIELLDEACAALDLDEETRSTAVDLFLSRAPDDDRGKRVAAAASLYAAGLIRGEERSQSAVADAMDVSRLSVQKRWKPILEDAGFSPPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ1</accession>
    <name>V6DUJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_11279</name>
        <name evidence="1" type="ORF">BN903_177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076628.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35238at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="301" mass="32724" checksum="79CB21D7BB781E13" modified="2014-02-19" version="1">MTDPIPVAVPRKGRPLEAVLERIAAVSDDDHLDRLADSVSNTLRYEKAVTKGAVDADGGPYERLAEYSDPETPAEPEFTLLRDDRGGKPRRIVFDAATVDLGDVTVKLVGREEPFRALRTHEFALGFDSADLVLEEVVGIRAAGLGNISDINDRIDPVDTDVRVVAGLGDTVYHTLMGREDDRAAGAAFDREYLTDYEGPLCISPRYERLVTAVLGTDALDGVEFVYPDADEEEEAAIARVGLGVYLTVTGSTAREHGLSVGEHLFPSETVLMRNAAEADESVSRVLRALEREAADSEIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ2</accession>
    <name>V6DUJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HQ_3567A</name>
        <name evidence="1" type="ORF">BN903_163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6646" checksum="1B9E25F121821CD5" modified="2014-02-19" version="1">MIKQWAEYVRTHDDREWSRQQNRLIDSQLQSANEMAAAGDTDPVRFAAARDRLRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ3</accession>
    <name>V6DUJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4589" checksum="7EDA3260FE766BB8" modified="2014-02-19" version="1">MSCTVVSVADVLMTRGVTRLYPLRRDDDPKTHFRGAAILAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ4</accession>
    <name>V6DUJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA processing ribonucleoprotein, binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_13148</name>
        <name evidence="3" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D RNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="PTHR10894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="SSF89124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0543">Viral nucleoprotein</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Nop" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="10801" checksum="47785B055A0AE473" modified="2014-02-19" version="1">MLGAEDALFAHLSGRASSPKHGIIYTHEFVRGTPPEDRGSAARALAGKLSLGARADHYAGERRERLHDDLRERMATIRARADSEENGAASDDGAEVTDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ5</accession>
    <name>V6DUJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative aminomethyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gcvT</name>
        <name evidence="2" type="ORF">BN903_183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5030" checksum="432A49969E102066" modified="2014-02-19" version="1">MSPTLDEPIGLGYLHESYADAGTEVSVVVRGDEKRAEVVIPPFLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ6</accession>
    <name>V6DUJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14443" checksum="4A2E5F3EF2105C65" modified="2014-02-19" version="1">MAESRRDRRRDVLVRVAPSLRREDSDRLAVCLPRAATDRLHDAAETAADDGVTAFRESFPEFLRDRRGLGADRTPADDADAHERAHAPAAGKPSESGVRRPQNTSSSFSPVLDVENPTETLIPSRRERKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ7</accession>
    <name>V6DUJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pNG6108</name>
        <name evidence="3" type="ORF">BN903_168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076898.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="200" mass="22786" checksum="266FF40EDA09FE6A" modified="2014-02-19" version="1">MWIPEAESDCVDGETYGQMPFWAVRKAAVALEICPEGAFIEREGENGTYKGFPGYETYNETLKAIGDAGLRHERDPISPEEVTDSEGRDKQDTRSDTASPDSQVSQLDQAHVRERNRLLSAKVDQLESELNEKTDRINMLETEVEHLQKELETVRSERDYLESALENNVLNQGSEQQTEEDPANDRSTLERARQFISFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUJ8</accession>
    <name>V6DUJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C467_12981</name>
        <name evidence="9" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004772">
        <property type="entry name" value="TrkH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006247">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="492" mass="52977" checksum="E494E4CABD287C40" modified="2014-02-19" version="1">MAGERGTHRRRPRRALAPAGVPAARRLLLRRVPLPFIAAIAVSLALGAAFRTVQDPEVNLGPREAFLAVALIWFLVAAVGAIPFVVAGVGTVAHPVNAMFESMSGLTTTGATVLRDFSLHSRSVLMWRQVIQWLGGLGILILATAVLSELGVGGAQLMESESQNQDVNKLTPKISRTAQLIWGIYLGLTMLAVIVYFGLGLAVDPQMDLYNAVAHAFTSVATAGFSPEPLSVGAFHPLIQWAVVPFMVIGSTSFVLIYFAINGEPMRLLRNEEFHFYLGAMGTLASIVAVGLFLDPGSNFGVEGTIRHAVFNVASIVTTTGYASTDYVQWAPAAKHMLFMGMFIGGMVGSTTCSIKSLRWLVALKSFRRNLFTAIHPESVRPVRISGKTVDEGAIRDIYAYLLLSIVIFFLLAIVIVVDAERADLPVTEFEALGAAATTFLNIGPAFGDAGPYGTFASFSLSTRAVMVVLMWIGRIEIIPVLVLFTKAFWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL0</accession>
    <name>V6DUL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HpcH/HpaI aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_12841</name>
        <name evidence="1" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6827" checksum="9DF33F623339D70F" modified="2014-02-19" version="1">MGPITEAFTPDPEDIEWARAVLDARDEAESAGRAVFEVDGEMVDAPLIAQAEGILDRAPETDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL1</accession>
    <name>V6DUL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase ISHwa3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_07104</name>
        <name evidence="2" type="ORF">BN903_183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076910.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44952at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="110"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="276" mass="30997" checksum="6B350BD8709C4C3C" modified="2014-02-19" version="1">MTQISRFIGEVVPVAQRVTGDGGESAAPEGGGGFADYALVSLHCLRIYLDTSYRMTIDLLKEMPQIIGEIGLDAADLPVPSTLCKAFDRISMSVCRVLLRQSAQLHDLSEHAAIDATFYERSAASRHYCQRISYRVQKLKVTKLVDTASQAVLDVHCSTNREGSDADLAEQIARRNAGDLRSLAADKGYDKQSLREGLRNLGIRPLIKHRIFAPYDHAHNARIDDNRYNQRSMTETVNSAVKRSLGFAVRAQSWFREFREIALMCMVYNIKRFVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL2</accession>
    <name>V6DUL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_09983</name>
        <name evidence="4" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077432.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19750at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="3">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="260"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="629" mass="68024" checksum="B69EFA3FA2B4A6DC" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL4</accession>
    <name>V6DUL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_12371</name>
        <name evidence="2" type="ORF">BN903_188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="376" mass="41327" checksum="D7B8F537DEBE4853" modified="2014-02-19" version="1">MPATDLEIALEKVDAGTFEKLAADILSERGYDVSPTEGVGADGGRDADLRRGTDTGVAHFTIRNDWKQKLRKDAQKTVNRELDRDFVVFVVNQLPEPPRVVDEVRDRLQDEFGFPVTILTRADLRTQLTTRNPYLAEEHLGIDAAKPTTDPVEEMEALKDERLSMIESRSNSLPNTLPSGPCAVLHLFPVGMFSTDYGVPPSELPSPPLFGGGRSHLAGRPVGDGVVSINSRIQEEHPEYVFLAEDGYIEAVTTLTFEQTTVDAFSPTDPNHVDPEVGKYLIQIVPGSLDVLDVLGAQPPVYAFVTLLGVEDYQFPTSYAGVSLGASLRPFSDQEEPKHSILETMDDDGTGLRPSLDRLWQRAGRQKGSPHFSNDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL5</accession>
    <name>V6DUL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamate dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_04013</name>
        <name evidence="2" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="1">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="10276" checksum="E7441045F0C8F9D0" modified="2014-02-19" version="1">MADRDVHIVPDILANAGGVTVSYFEWVQNRQRFSWTEERVNEELERVITDAFDTLVETYESNDVHTLRTAAYVVGIGRIVDAYDQAGSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL7</accession>
    <name>V6DUL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton-translocating NADH-quinone oxidoreductase, chain N</fullName>
            <ecNumber evidence="7">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_02651</name>
        <name evidence="7" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077438.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="28394at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00445">
        <property type="entry name" value="NDH1_NuoN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010096">
        <property type="entry name" value="NADH-Q_OxRdtase_suN/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01770">
        <property type="entry name" value="NDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="6">
        <location>
            <begin position="133"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="501" mass="51802" checksum="DCE71C41A7E4B410" modified="2014-02-19" version="1">MVETLPQVTALLPALVLAATGLVLLLVDTISPDARSNTSMAVVSALGALASLSVTVWFVASGTGSVDTGGAITLFADAIKVDTMALFFTAIFASVTALVVVAAHDYFHDHDNPAAFYSLTLFAATGMALLAVANSLAVVFVALEMVSLPSYVLVAYLKQDRGSVEAGLKYFLVGALSSAIFLFGISLVYAATGSLILADIASASIEGLAGVLGVGVVMMIGGVAFKTASVPFHFWAPEAYEGAPAPVSAFLSSASKAAGFVVAFRVFTEAFPLGMAVSANVNWMLAFAILAAVTMTLGNFAAAVQEEVKRMLAYSSIGHAGYALIGVAALTLDGPANGTVMGAAMAHLLVYGFMNTGAFLFVAMAERWGVGRTFADYAGLWRRAPVASVAMAVFMFSLAGLPPFAGFFSKYFLFQAAIDNGFLWLAALGAVNSVVSLYYYSRVVKALFLDDPESPSALDAVDVRPTALYAAVVFAAVATVLLLPGFGPVIETAEAAASALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL8</accession>
    <name>V6DUL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3099</name>
        <name evidence="1" type="ORF">BN903_193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7519" checksum="57A4B46987EE1C39" modified="2014-02-19" version="1">MNRLEDVGYISYDDGLSVVDKRVRDAAHELVAASAGVTLPLVREVLRERVLDRRLDGATTRHWASEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUL9</accession>
    <name>V6DUL9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="2">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="2">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">msrA</name>
        <name evidence="4" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077384.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86136at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="3">
        <location>
            <begin position="6"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="179" mass="20125" checksum="4248842497369B29" modified="2014-02-19" version="1">MTNTETATVGGGCFWCVEAAFKELDGVESVTSGYAGGHAEDPSYREVCSGNTGHAEVVQVEYDHDALSYEDILEVFFTVHDPTQLNRQGPDVGSQYRSIVLTHDDDQHEAATRYVEALDEEGGYDDDVVTEVEPLETFYRAEEKHQDYFEKNPADAYCTMHAQPKVDKVRERFREKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM0</accession>
    <name>V6DUM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine synthase II (Cobalamin-independent)-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12791</name>
        <name evidence="2" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25749at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meth_synt_2" evidence="1">
        <location>
            <begin position="173"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="383" mass="41541" checksum="09F23561E2008D19" modified="2014-02-19" version="1">MANDAHIGTTHIGSLPRPPALLDLLTKRQDGEDVDGDEWDATVAEATRDVVDRQVETGLDSINNGEQSRVSFNWYVADRLSGIGGTQETELWADLQEFPSYAEETFKTDVIDLSEHPVVDGPIEYTGREEAEAEVDGLLDALEAADRDADDAFMTAASPSVVTATHVDEHYGDYEEYLFAVAEAMKTEYELVADAGLTLQIDAPELLTVGHTAAYADEPLEAAKDATRLHVEALNEALANVPAEQVRLHTCWGSYEGPHHLDTDLAEMLPLIYEADITGLSVEQANPRHQHEYRAFGEHPVPDGWTLIPGVVDVKTNIIDHPETIADRLERVADAVDDGIPLVAAPDCGFGTQAGLGMVDPEIAWAKLDALVGGAEIANERLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM1</accession>
    <name>V6DUM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HalDL1DRAFT_0552</name>
        <name evidence="1" type="ORF">BN903_207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5429" checksum="7AAF962D60F8973E" modified="2014-02-19" version="1">MAESQYASIPVRPETRDLVRSLKRGGQDYDSLVRQMCDQYDPDETAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM2</accession>
    <name>V6DUM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH dehydrogenase subunit J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_10048</name>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006629673.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38944444"/>
    <dbReference type="OrthoDB" id="126867at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001457">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00499">
        <property type="entry name" value="Oxidored_q3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9300" checksum="A0EC66B79CF27898" modified="2014-02-19" version="1">MVEVTIAFGLFAAVTLAFALGVVLARDVFHAALLLGGALTSVAVHYVMLRAEFIAAMQILVYVGGVLILVTFAVMLTRSDSETEVSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM4</accession>
    <name>V6DUM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-ubiquinone/plastoquinone oxidoreductase chain 3</fullName>
            <ecNumber evidence="7">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_10073</name>
        <name evidence="7" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077446.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101537at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000440">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038430">
        <property type="entry name" value="NDAH_ubi_oxred_su3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11058">
        <property type="entry name" value="PTHR11058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00507">
        <property type="entry name" value="Oxidored_q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15086" checksum="82C4791C08B5FD42" modified="2014-02-19" version="1">MSDWIAIGALAVVGLLIPIAMMTVSALLRPSVPETGKSTTYESGETPTGGTRIRFNIQYYMVALLFVVFDIETVLLFPWAVIYRPAVQAGVPMADLLWPMLAFVGVLAVGLVWAWRSGAISWARSPRATSRKTTEEPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM5</accession>
    <name>V6DUM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ZOD2009_20432</name>
        <name evidence="1" type="ORF">BN903_212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="17089" checksum="D8A5A3C89014292B" modified="2014-02-19" version="1">MITKCMTHIQDVRSVIRDSTPNQWEYFEQVAPQVSVTSNPDTICYVYEEDVNIRLERGAVAVQDFDEPWVPGAGGQTDSYVWWLTYQNSPVEQFVVVSVDGGRANIPVPDGGQSDGDTPTLTEREANLGRIFDQHSLNGFDDYIDRSDVEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM6</accession>
    <name>V6DUM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04955</name>
        <name evidence="2" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="11888" checksum="F0EABD5CC5AA1BB2" modified="2014-02-19" version="1">MHRLSLSMMSEIVCGRRKAEVGARRFSRSPAEGEDMSDESGGSAFTEGYVVPIAGLLALMFALMAGLTAQRALSGDPADIAVTVGFAAVAVIALRIRIKAVAAKGGDATDDASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM7</accession>
    <name>V6DUM7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="3">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Alpha-IPM isomerase</fullName>
            <shortName evidence="3">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">leuD</name>
        <name evidence="5" type="ORF">BN903_203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the LeuD family. LeuD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076924.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86621at2157"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01032">
        <property type="entry name" value="LeuD_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011827">
        <property type="entry name" value="LeuD_type2/HacB/DmdB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02087">
        <property type="entry name" value="LEUD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="2 3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="4">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="175" mass="18845" checksum="C3685D5E24A741F2" modified="2014-02-19" version="1">MTDTDVDRDIDTTEPGRAWTFGDDIDTDQIIPSRFLVSSDPAELGKHAFNDLRTEFASNVAAGDFVVGGHNFGSGSSREHAPVSLLGAGIDGIVAQSFARIFFRNGINLGLPVLICPDADQIDDGDAISLRLDKGAVINHTADERYNADPLPEFLQTLVDTGGLKPYTRAKLNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM8</accession>
    <name>V6DUM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4656" checksum="39CFCD045F0492FB" modified="2014-02-19" version="1">MFGPGDLADESGAVAHAEREYVRVREVEAAAATVADAVLALLGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUM9</accession>
    <name>V6DUM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase c2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12776</name>
        <name evidence="2" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="225" mass="24201" checksum="1B2300D38CA3912D" modified="2014-02-19" version="1">MTDSPPWADLFGHPEPYPEQADGIDAAIDAAEDGGFLALEGACGTGKTMLALTAGLDRVRDPESDFERVFVLTSVKQQLRQFETDLQTINDDFPSDYDPVSGLTLVGKADVCPYARENRGGIDRENVYERCEGLRERTRNLVGDGGATTTSNLVSEARSQQVGLMDSGNAPDSDGAADYLSVDGEPTRTGRTPRSTTGPSSRPFYAASSTTSRRTATPPRRSRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV00</accession>
    <name>V6DV00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="22998" checksum="C8E20276AB628522" modified="2014-02-19" version="1">MAVIGVLTEADVADHRRVRLRVDPPDCPLDDAVVGVRPAPLGVFRLGDAEEDHGLDAGLGDLLDAVDRLFDRDALVARHRLDRHALVGRRVDEDGCDQVGRREVGLGDQRANAVGPESAWPVREVHVGALAPRGLLAFVSKRGVRWPSATGGAGGPTRRRAKQCDYSEDSMSIRSRSSASSSDSASSSTRCLKCDSQSPTTTPRCSASYVASRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV01</accession>
    <name>V6DV01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_08710</name>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076805.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101233at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="4"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="169" mass="18135" checksum="1E5EE51F89AC558D" modified="2014-02-19" version="1">MTIETVLLPVSDSDEDRLNRLIDTVLEIAAPTDATVVVAHAIPEQDDGVVTTIPAISGGNYPQTLSQPEYDDLLDRYSDSDHSVDEVVSEHETVQSVTDRLDEAGVEYEVRGAVGDPSEAILELAGDIDADRFVIGGSRRTPTDKAVFGSLSQTLLLEAPCPVTFVHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV02</accession>
    <name>V6DV02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5846" checksum="1474939E26D03514" modified="2014-02-19" version="1">MFTSICSGGSVSAGRSSIVEITPVPPANVDWRMRTAVSIIGMTRCRQPNKANYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV03</accession>
    <name>V6DV03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10692" checksum="2F627A2B673BABB7" modified="2014-02-19" version="1">MDRLAVPVDAQVNLDRVRSVVFRRKLREMNSGVAGDSVKTASNRNRRRKPDTREEGASLHTSYGQSPTKSLLTAAAQAVTATVRTAMCSIDTERFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV04</accession>
    <name>V6DV04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_11976</name>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="25474" checksum="3829D1DE21D51283" modified="2014-02-19" version="1">MDGGPGYEERDRNCATNFAAAASAAGIDRIVYLGGLGEDRDELSEHLRSRREVERILADGDPALTTLRAAIIIGAGSASFEVIAGLARRLPVMVTPKWVDTLCQPIAIADVVAYLAGVLDVPETAGETFEIGGPEVLTYAEILRRTRRQLGGGLRIVRVPVLSPGLSARWLRLVTDVNPYLAQSLVEGLRNTVIVEDDRIGEFVSVELTPFELGVARALTDSRNAEGSRLSALPGVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV05</accession>
    <name>V6DV05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05963</name>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077533.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107186at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14520" checksum="69A00A177C7F3A42" modified="2014-02-19" version="1">MTVVPTEWSEPDSRLGVYYELLWIGLAILGFGAVAYWEPFSITVSITPQRLAGATTLGVALGIAVTYGSFVSERSQRLWENSRIRFAGLFIFVMGVQLGLNVAPTWTVLTMLALLFTLIPLRVAIYFRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV06</accession>
    <name>V6DV06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C471_08700</name>
        <name evidence="5" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076937.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118027at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="10956" checksum="D4B690A09081A93F" modified="2014-02-19" version="1">MSWLILFVAGLFEIAWAIGLEYSDGFSEPIPTAGTVAALVISMVLLGKAVQDLPIGTAYAVWTGIGAVGTASLGIVLFDEPATGARLLFISVIVCGIVGLHLVSGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV08</accession>
    <name>V6DV08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8120" checksum="BBAD1324A31B5991" modified="2014-02-19" version="1">MVRDAFGVSSSRKARSAFQTTASVRPPRGWGFGGHAAGSNCVVASGWESGAAHRGNRSLQSYVSTPRIRSRVREKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DV09</accession>
    <name>V6DV09_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase II small subunit</fullName>
            <shortName evidence="12">Pol II</shortName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Exodeoxyribonuclease small subunit</fullName>
            <ecNumber evidence="12">3.1.11.1</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">C472_07490</name>
        <name evidence="12" type="synonym">polB</name>
        <name evidence="14" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">AJ67</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EC" id="3.1.11.1" evidence="12"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008852">
        <property type="term" value="F:exodeoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000738">
        <property type="term" value="P:DNA catabolic process, exonucleolytic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00325">
        <property type="entry name" value="DNApol_II_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011149">
        <property type="entry name" value="Pol2_small_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="PTHR10416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000803">
        <property type="entry name" value="Arc_Pol2_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 12 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol_E_B" evidence="13">
        <location>
            <begin position="140"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CDK40054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="392" mass="43462" checksum="F36C294D4F3AD964" modified="2014-02-19" version="1">MTGRSTGTGEYADFVTTFRDRYERLSKILRGRVNHRPAEAIADMPGGSDAAMIGLVNDVRSTKSGHWLVELEDTTGTFPALVMKDKGLADVVDEILMDECIAVEGTLADDSGILFADSLHFPDVPRTHRPGGADRHVQAALISDVHVGSDEFMADAWHSFTDWLHTPEADPVEYLLLAGDMVEGVGVYPDQDEELEIVDIYEQYEAFAELLKEVPADTEVVMIPGNHDAVRLAEPQPGFNDEIRSIMDVHDPQIVSNPATVSVEGVEVLMYHGVSLDEVIAELPEEKASYDEPHKAMYQLLKKRHVAPQFGGHTRVAPEERDYLVMEDVPDVFHTGHVHKLGWGKYHNVLAVNSGCWQAQTDFQKSVNIDPDAGYAPILDLDTLDMTVRKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYR0</accession>
    <name>V6DYR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="12072" checksum="BAF04A80D0E16AE6" modified="2014-02-19" version="1">MTVFVEIDFVTKTAEAPVARLYVTAFIESNLAAETASRLGLRVPPLRKTFLLASLRGLRLPCSRSLRSRERTATAPHASPASSVAVASLRRLTPSRGAASRPPGAAARRHAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYR3</accession>
    <name>V6DYR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6682" checksum="82FEFD13E2038770" modified="2014-02-19" version="1">MDRCVSEHHHDNELDQQPRNVVRDLVPLLCDPRSFRLHCRRCRSAVSEDIFSEHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYR4</accession>
    <name>V6DYR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06330</name>
        <name evidence="3" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077906.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63240at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013971">
        <property type="entry name" value="HalX_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08663">
        <property type="entry name" value="HalX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20576" checksum="214112076FF5A248" modified="2014-02-19" version="1">MSDPSILVVEDEPDIAALYAGFLEERYVVDVAETAAEAIDQVDAAVDVVLLDRRLPDGSGDDVLEHIRKEGYDCRVAMVTAVEPDFDIIDMGFDLYLTKPVSRSKLLAAIDTLLTRSEYDDLVREAAALASKRAVLSSQKPAAQREGNEAYAELVERLEDLDADIDDLGESLSTDDYRAMFRDLGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYR5</accession>
    <name>V6DYR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TP009.40</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077904.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117611at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="10540" checksum="C0D53AD2BB177FA5" modified="2014-02-19" version="1">MNPATPTGIAVLIAIVNSALLAVLAGVWLDNYHEFGSTLLLGLLGFCAVLLVENLISIAFFFSSMRTLYAMDPLVGRVVLGLSLLELLAVSLLTYATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYR8</accession>
    <name>V6DYR8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Threonine ammonia-lyase</fullName>
            <ecNumber evidence="3">4.3.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ilvA</name>
        <name evidence="5" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04886">
        <property type="entry name" value="ACT_ThrD-II-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044561">
        <property type="entry name" value="ACT_ThrD-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005789">
        <property type="entry name" value="Thr_deHydtase_catblc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01127">
        <property type="entry name" value="ilvA_1Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="222"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK41011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="297" mass="31476" checksum="9C80E31F487C3325" modified="2014-02-19" version="1">MKATRGYGASVRLEGVDYDEAQAYAHQLEREEGRTYVHAFDDPVVMAGQGTLGLEIVDDCPELDTVVVPIGGGGLISGVAVAIKEQLPDARVVGVQAAGADSAAQSLEAGEVREIEGVDTIADGIATRSVGEQTLEVMAEYVDEVVTVDDREIALALTLLLERSKTLVEGAGAVALAAVLSEAFEYDDGETVVAALCGGNIDLNRLGTVVRRGLVQMGRYLKITIDLKDRPGELERVSSIVARTGANVYAVHHDRTSRDVAVNAAELELELETDDAEHAADIVDALEAEGYEVEIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYR9</accession>
    <name>V6DYR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_10468</name>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077908.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115561at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="11572" checksum="8024FB10BE4F12E4" modified="2014-02-19" version="1">MELIEGLYLMTTTVLAGASATLVAFAVAAYRSSGRTAMAYLAVGFGLVVLAAVGTPAAAFRTEFGNAEALLLVNTGLLAASMALIAGSLAVYEPGTQEFVIPESELSRLRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYT0</accession>
    <name>V6DYT0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagellin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_10413</name>
        <name evidence="2" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077947.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106000at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42200">
        <property type="entry name" value="PTHR42200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="16304" checksum="502F21762A78AAEB" modified="2014-02-19" version="1">MGVSVSASTAIIVAGLFFAFTTFYPVAANGLDRVSDAQHGVNERALERQNTEFAVTNATYDTTSDILTVNATNEGSVGLVADDATLVVGNEYVDVGGPNATTTVDGDADTALWLGDEQLTVEVAQNDTSTTIEEGTRIVLVVESGVRDAATVTEVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYT2</accession>
    <name>V6DYT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_10403</name>
        <name evidence="2" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077913.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60868at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="27"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="249" mass="27487" checksum="43835FAA96BABE1C" modified="2014-02-19" version="1">MPHDNLLSLGLGERDRLNKELGGGIPRGSIVLMEGDYGAGKSAISQRFAYGLIQEGASVTMMSTELTVRGFIDQMHSLEYDMVKPLLQEELLFLHADFDSGGAFSDGDGERKELLKRLMNAEAMWNSDVVFLDTFDAIFRNDPTFESLVRKNEERQAALEIISFFREIISQGKVVVLTVDPSAVDDDAIGPFRSIADVFLQLEMVEVGNDIRRQINVKRFAGMGEQVGDTIGFSVRSGTGIVIESRSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYT3</accession>
    <name>V6DYT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10056</name>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8415" checksum="562A33284CBF0454" modified="2014-02-19" version="1">MVGPISEAERDAGNRKIKLVLLAIVTVSPPLIALQLNPSPVQLLAALGGGFLLGLAVVWYLGRLAAEFSGGRRRPGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYT6</accession>
    <name>V6DYT6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protease HtpX homolog</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">htpX</name>
        <name evidence="13" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase M48B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077916.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="M48.004"/>
    <dbReference type="OrthoDB" id="62484at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="12">
        <location>
            <begin position="75"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CDK40530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="290" mass="32191" checksum="D593E1A04FE20867" modified="2014-02-19" version="1">MEWKTDWGLRGRMGLTMFLLFALYVAFVGVLVTFFDVGSLTILIMLGGFSLAQYFFSDKLALRSMGAREVSADEYPDLHRRIERLSQQADLPKPTVAVANTQVPNAFATGRNKKNATVAVTTGLLESLDEDELDGVLAHELAHVKNRDVMVMTIASFLSTIAFFIVRWGWLFGGDNRQGAPVIVAILVSLVVWVISFLLIRALSRYREYSADRGAALITGQPGALASALMTIDGRMDKVPKEDLREEAEMNAFFIIPIKAGFVGKIASTHPSTENRIERLREMEKELETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYT7</accession>
    <name>V6DYT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock DNA-binding domain protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Nmag_1855</name>
        <name evidence="3" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="11"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11672" checksum="2349B5E863408211" modified="2014-02-19" version="1">MPPQSERMFVMANGKVDFFNNTGGYGFISTDDSDDDVFFHMEDVGGPDLEEGQDIDFDIEQAPKGPPCDERRPQLTRGSTSPHGDDRRLVSFGTTLPRRATRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYU1</accession>
    <name>V6DYU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8104" checksum="C406DC77B8F558A4" modified="2014-02-19" version="1">MPSLPFPPSPPSVPLASSLPPSVPSPSPLPSAPSVPSASGSARSASGRSSRTPSGDGAWVIVTLVPSRSTPYAPGKSLSSPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYU2</accession>
    <name>V6DYU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase T2 asparaginase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_10091</name>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6366" checksum="3E6CAD759527CB2D" modified="2014-02-19" version="1">MTLSRRAVKYLDDGVGAQAAAERAIDEFEEITGSGAGVIVLGDDEAGSAFNTEGMQTSVADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYU3</accession>
    <name>V6DYU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMMECR1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06225</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077917.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107157at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="PTHR13016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00296">
        <property type="entry name" value="TIGR00296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="12"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="200" mass="21625" checksum="42AB4808E78E2AD4" modified="2014-02-19" version="1">MSEAQTVQLSYDDGARAVELAREAVESFVQHGQREQPGSMREAFYARTGAFVRLESTRGRGRLRGCAGAWETSDQLGHAIVEAAIKAASDDSCGSEVEPKELDNLTVSVFVVSNTILTNDPLEDLEVGTHGVAVDSGNAHGWLYPTVPVENGWSGAEFLSRACRKAKLSPTAWQEEDTIVTLIEGQVFRERADGGAVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYU6</accession>
    <name>V6DYU6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="5">BCAT</shortName>
            <ecNumber evidence="5">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">ilvE</name>
        <name evidence="6" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000027">
        <property type="protein sequence ID" value="CDK41041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078387.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000027.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41340at2157"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 5 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="309" mass="34770" checksum="2CFB5C0B697BC6E9" modified="2014-02-19" version="1">MGFDEMDVDTIWKNGEFLDWEDATTHVLTHALHYGTGVFEGVRCYDTEQGPAVFRWEEHLDRLFDSAKMYDMEIEHSREEITEATLELLDRQDLESCYIRPIAYYGYDTLGVSPKDCPTDLVLAAWPWGAYLGEEALEDGVDVMVSSWRKHASSQVPTNVKTTGLYVNSMLAGEEARRNGYVEAIVLNKEGNVAEGPGENIFMVNDGEIYTTGPAQSILEGITRDTVITLAEERGYEVHDEAVISRGQLYTADELFFTGSAAEVTPIRSVDDTEIGAGTRGPVTEELQSAFFELVERRTDDHDEWFTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYU7</accession>
    <name>V6DYU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphonate ABC transporter, ATP-binding protein</fullName>
            <ecNumber evidence="8">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">phnC</name>
        <name evidence="8" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077923.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72957at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03256">
        <property type="entry name" value="ABC_PhnC_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012693">
        <property type="entry name" value="ABC_transpr_PhnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02315">
        <property type="entry name" value="ABC_phnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="286" mass="31090" checksum="F58E3A5E44243D1F" modified="2014-02-19" version="1">MLETENLGKTYPTGDEALRDVSVTIGGREVVAMIGPSGAGKSTFVRCINRLVEPTTGSVRLDDRELTGLGEDELRNARRDIGMVFQEYNLVERLTVMENVLSGRLGYVSNWAALRRNFPPEDVERAYELLDLVGLDDMENKRVDELSGGQRQRVGIARAVVQEPKIVLADEPTSSLDPETSRDVMELLTDIAVERDVPVVINIHEVDLAERYADRILGLHDGELVFDGPAADLTDESKGVIYRGEELPASAATDPDRLSNGTGGEGTPEITGDGSNAGNGRLPAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYU9</accession>
    <name>V6DYU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Squalene/phytoene synthase</fullName>
            <ecNumber evidence="2">2.5.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06180</name>
        <name evidence="2" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077921.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62240at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016767">
        <property type="term" value="F:geranylgeranyl-diphosphate geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="321" mass="36580" checksum="F091093065528945" modified="2014-02-19" version="1">MVEQKQVARSKRIQRRTGKTFHVATRLLPQRIRHPTYVLYGFFRIADEVVDAADTAPPAEQRAELDRLRATALGEEPTDDPVLEAFAEVCERNDIPDADVHSFVDAMASDIDTDRYETYADLEAYMDGSAAAVGRMMTAIMDLDPEAEAEALPHATKLGEAFQMTNFLRDVREDVVERDRIYLPLETLRRHGVSEQQILDLEFDEHVAAAVREEMARTERLYEEGVAGIKYLPEDCQLAVLLAAVLYVDHHRLIRNRGYDTVSATPELSFARKISLLVRTRWKWQWNRDPEAVFYDMCTDFDPGHDRHGHGPHGTGVPQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYW0</accession>
    <name>V6DYW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oligopeptide/dipeptide ABC transporter ATPase</fullName>
            <ecNumber evidence="5">3.6.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_09448</name>
        <name evidence="5" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.24" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="45"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="128"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK41056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="22751" checksum="F3B3644EDAAB8E4A" modified="2014-02-19" version="1">MSDPLLSVDGLKKYYADDQSLVDRLLGAESESVKAVDGVSFDVREGETLGLVGESGCGKSTTGETVLRLREPTAGEVTFDGADLREMTDGELTEFRKRAQIVFQDPFSSLDPRMTTGDIVAEGLRIHGLPRSDPSVETTADLTVEGASLDAGAVYGSRRRRRRPTSSTPREGSRGSPSPSARTRRASSPPSTGRETCSERLSRRPATRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYW1</accession>
    <name>V6DYW1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="3">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">panB</name>
        <name evidence="7" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3 6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077935.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60112at2157"/>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="3 5">
        <location>
            <begin position="40"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5 6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="27954" checksum="7E144649FCDAEBB0" modified="2014-02-19" version="1">MTTTRGLREGDDPITMLTAYDAPTAAVVDDAGIDIALVGDSMGNAALGYDSTLPVTFDEVASRTAAVARATEDALVVADMPFLSFGVDEAESVRNAGRLLKEANADAVKIESGPHTVETTRRMTEVGIPVMAHLGLTPQHVNRLGGYTRQGTEQDAAEEIIDLAGAHADAGAFALVLEHVPANLAGAVTEALDIPTIGIGAGPDCDGQVLVINDAVGLGEWSPPFAKQFGDVRGEMIGAVEAYKEAVESGAFPADEHSHVEEDLEDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYW2</accession>
    <name>V6DYW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09266</name>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077957.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101947at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="13061" checksum="E26667640B814926" modified="2014-02-19" version="1">MSEAQAVTDESTAASDLTAFQQNILSILAEEPMYGLAIKRELESYYGSEVNHGRLYPNLDDLVELGLVEKSELDKRTNQYELTDAGHDVVLGQIEWILDRFVTDEARADEVRALLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYW5</accession>
    <name>V6DYW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_09418</name>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000028">
        <property type="protein sequence ID" value="CDK41061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="14357" checksum="C8F687CCCEDFC602" modified="2014-02-19" version="1">MSDAESTADAYEERGWNVLAAHPGDVNPVVDAARIDVLLPGSEFETALSAVEDAAIDGVDVYAGTAGGVAYRLVVATGEAAQVALCVPTYLRNDDLSSLRAAAEASGALTVRLRPLDDRDHAEIAIDDPAVFFDAPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYW7</accession>
    <name>V6DYW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077961.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8744" checksum="CD200FEA8467743C" modified="2014-02-19" version="1">MISPVLAFGGVPGGPELLILLVVFALLFGVPLVVIVGVVVFLKLRADDEEVDTDRVAELEAEVERLREKVDDEPDDGDARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYW8</accession>
    <name>V6DYW8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">ppa</name>
        <name evidence="6" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077955.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103587at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="20381" checksum="EBCCBB3728F4F6CA" modified="2014-02-19" version="1">MVNLWEDLETGPNAPDEIYAVVECLKGERNKYEYDKDIPGVVLDRVLHSNVHYPYDYGFIPQSYYDDEDPFDVMVLVEDQTFPGCVVEARPVALMKMDDDGEQDDKVIAVPTEDPRFDHIEDLEDIPQQILDEIDEFFATYKNLEAGKEVETLGWEDKQAAKDAIEHAQDLYDEQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ30</accession>
    <name>V6DZ30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08776</name>
        <name evidence="3" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077996.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101342at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="117" mass="12789" checksum="100F2223E7362A26" modified="2014-02-19" version="1">MEPLVAVILVGVPLAWLVGFAAYAYVDAPKHGMDPRKWAVIAFVVPLFGFLAYVFERDEQGYDPESDPYAEGSEERTGGFAVHESRQGEKRLGPAGTEADEGDDADDEWNDPDGVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ31</accession>
    <name>V6DZ31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C472_05481</name>
        <name evidence="12" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000039">
        <property type="protein sequence ID" value="CDK41136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078477.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000039.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90656at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026469">
        <property type="entry name" value="Peripla_PGF_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026371">
        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04281">
        <property type="entry name" value="peripla_PGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0701">S-layer</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="11">
        <location>
            <begin position="83"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="326"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK41136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="407" mass="41714" checksum="50733E151FB61ED8" modified="2014-02-19" version="1">MRNSFAIAMAVLVTTALLGGVAGTAAGAQPTISTEGPTAVGGSAAGEIGTADAPTQTDDACGFPVEVTDATGTTITLNESPDRITTINPSAAQTLWELGEQDRVVGVSQFALYLDGADERANVSAEFGASVERVVDTEPDLVLAPNSSSADVQPLREQGLTVYHFQAATSIDDIAEKTETIGRLVGACDAASETNEEMYDAVDAAENRTGDVDRPAALYPLGGGYVAANNTFIDAIMNAGGTDNVAAEYEAYPQLSDEVILETNPELLLVTDSEATILDQEPYASTTAGVEDNYVVMNRNYLNQPAPRSVIESTTTLSNAVVEIQADSEGSTDGSSGDTDDDSPSDGDDSSGDGEDGSNDGDADNGTDLTTADGNETDGNTGAESPGFGVVAAALALLATGLLARRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ33</accession>
    <name>V6DZ33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C445_17059</name>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078029.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107331at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="16002" checksum="ACE99338D9C13A31" modified="2014-02-19" version="1">MLLNDTEIQNNIDEFVEAHGVEGFFRVYLREYLFQLLNKEIEAATNDPESDSALQLHFSQNVETDQEIEEFEEQLRDQCANRADELVEKIQDQPELAPIFEDVDVELLEHEDVEEMIRNTMHEMIKTWGDEDLEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ34</accession>
    <name>V6DZ34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000041">
        <property type="protein sequence ID" value="CDK41141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4592" checksum="65AE0971F2E49ABF" modified="2014-02-19" version="1">MDTVCRPSRSLASFVAIGMSELLKLYIERIKQILINYVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ36</accession>
    <name>V6DZ36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_16732</name>
        <name evidence="1" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7935" checksum="CB8C6D3C61454AA1" modified="2014-02-19" version="1">MRALLDTVTDRSGIEFTVREHHESQQEHYPTHYVDISIQYRAVLNHPNTTSIDVMVDEHVAFDPVCIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ37</accession>
    <name>V6DZ37_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="148" mass="16831" checksum="F416BC9E3995AF15" modified="2014-02-19" version="1">MGLKRQAGGWTQFTRRCFWRWTMRLFSRGRGEGRRLRVYVSTEQHRASGTDGVLRGHDVGSDAARTPRRRAGSGRGRELPSLRRTGGHDRVRGAARVPGRNDRLADETDADHRGRIHHPYRRRRSGHHGKKSDRNENTGAPTAGSRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ39</accession>
    <name>V6DZ39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_16214</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000042">
        <property type="protein sequence ID" value="CDK41146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078487.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000042.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122908at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13463">
        <property type="entry name" value="HTH_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11965" checksum="C6DAF282BC1D67CE" modified="2014-02-19" version="1">MPESSSDPPAETDLDVLIDDATTAVDVKALSAFGYETRYRLVRLLVETDDAVRFDEITPYVSISDSAVSHALTLLCDAGLVEKEKDGRSRRYAATRRAEALVTALDDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ52</accession>
    <name>V6DZ52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LPS glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TP009.51</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000047">
        <property type="protein sequence ID" value="CDK41161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="200" mass="21717" checksum="BE45D13EFDE8D9C7" modified="2014-02-19" version="1">MLGWGFPPNITGGLDVHVGELFTGLRDDLGVDVTLVLPAEFAPDDGPGLEPVETGEGDVAARVGQLSDRFAELAPDHDVIHTHDWFGYGPGRAAARESDATWVSSFHSLASDRNIDPPSREVETERRLANAADTNIAVSEIVREDIRELYDADSRVVYNGFSTPTFSGKDVRSDLGIDGEMLFFVGRHTDQKGISTSCTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ56</accession>
    <name>V6DZ56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C493_00335</name>
        <name evidence="3" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="128"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="359" mass="42194" checksum="7D4EE60195087DA0" modified="2014-02-19" version="1">MRVDFFRRWLNDELSWVIYNEDDEHEIAEKRNKWREEVIQHESEVNWTTGGDLRPENLSIDEAHNYFQALSACPRYGGGSEVSHVKAIRQFYEFTLNRGHSWFTSTGNPIELALNEGGDKIIGSKSSRNPEIISVDEMGEYIRSFSHPLFESLTALMAKTTIRRGVTHNLDLQDVYLDHPACDWKVHRELRHKDRPFIYISSKPEEGKLWEERQRVPKSSNKTSVDRTIPIDNELCDLLLRWLVIHPGPLESNTPLFVSLFRNWGERIHAQTLQKKLREHSEDLGYWYEPYDDDNINPHYFRHWSTSVIDQRLEAAGAGGHSTTTKLIRGDEEDTMDNYTHWSDDRVKRYLQVCPKFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ57</accession>
    <name>V6DZ57_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable GTP 3',8-cyclase</fullName>
            <ecNumber evidence="11">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">moaA</name>
        <name evidence="13" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="11"/>
    <dbReference type="EMBL" id="CBVY010000049">
        <property type="protein sequence ID" value="CDK41166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078503.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000049.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18533at2157"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_A">
        <property type="entry name" value="MoaA_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013485">
        <property type="entry name" value="MoaA_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02668">
        <property type="entry name" value="moaA_archaeal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 11" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="8"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="263"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CDK41166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="334" mass="37168" checksum="E3CF2B92812D3111" modified="2014-02-19" version="1">MAGPLADDFGREVTGVRISLTDRCNFDCVYCHNEGLGDTRGPMEPSESEMSADDVVRFLEVVEGYGVDAVKFTGGEPMLRQDLEEIIQRTPDSMEVSMTTNGTFLPGRAADLKAAGLDRVNVSQDALDPDDFAEVTKSGAYEKVLEGVKAAVDAGLDPVKLNMVVFTHTAGYVEEMVEHVAENEGLQLQLIQYMPELTGKPEWNVDIGRVHDWLAEEADRVEHREMHDRKRYFVGEESDDETGGMVEIVDPVENEEFCANCGRVRVTHEGYLKGCLNRNDDLRSMGEMTREEIAETFEAVVANRVPYYGEYLVEGDDGEYELNEKYLGTPPAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ60</accession>
    <name>V6DZ60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_02690</name>
        <name evidence="1" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078050.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128367at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8332" checksum="704295266B97CFEF" modified="2014-02-19" version="1">MTDADIDIAETIDRLEEIAETLEDGEVDLTTAKELREEADDHLEKLRDALDVGDGDIIEIDGEDANIEASESATQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ61</accession>
    <name>V6DZ61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="7332" checksum="3B51BEF14DBE5BCF" modified="2014-02-19" version="1">MKREKRDRYNTMSDRYCLSRAGSTNTPYCFTVTEIRNSCVAYLKPRQRRHRLGLPLDRRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ65</accession>
    <name>V6DZ65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_15886</name>
        <name evidence="1" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078053.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114573at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8513" checksum="BC98E1938451CE54" modified="2014-02-19" version="1">MPDTLTDEYPEAAPFIAEAAEDHGEEWVLENYYTELYPLSQVMTMSEKEELPFFDPDIDEAMAKDEQIKMYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ80</accession>
    <name>V6DZ80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase I</fullName>
            <ecNumber evidence="1">6.3.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purQ</name>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010075">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurQ"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01737">
        <property type="entry name" value="FGAM_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="17274" checksum="E2CB5F7EEB9B3E11" modified="2014-02-19" version="1">MAARDPIMDEVRAAAESGVPVIGICNGAQIGSESGLTPGAFTTNASARFQCEPVHLRVERADTPWTAAYDEGDVIEVPIAHGEGRFEIGDEAHADLVADDRVLFRYCDADGNVTDAANPNGSTDNVAGVLGERETVAVLMPHPERATLPDLGRSTDGAGILEAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ81</accession>
    <name>V6DZ81_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C488_08022</name>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078034.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="53583at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13463">
        <property type="entry name" value="HTH_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="306" mass="35906" checksum="589C1F9ADE5500FD" modified="2014-02-19" version="1">MLRRIELEVLATIDRGDTISELATKLDHSESYLSRGIGDLVEKRLVYTERDGRRKRVVPSDARAVELYQDLVRQYPHIDFPELLTGKTLEVLYYLDQPRTVAEIADRSDNYRNTVNRVLKRFRDRGLVGADDGRYDFNADFTRLHEFARELTHHLHRQRLEAVAPKGTILWEDYNAFLAQTRTEIDIEAFHETGLARFAAFDLQFLLTDHRYYFYSEELDILSPADLCCHTLLIDDSSRYRSYCLLLLRQVDVDEGDLREQAAKYGLEDEIDALLRYLETHGDVTDDRLLEWDEFQKLAAEYEIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ85</accession>
    <name>V6DZ85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_09845</name>
        <name evidence="2" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="17840" checksum="6683D11C967A6C4C" modified="2014-02-19" version="1">MTDAEDETFSGDSQPGEQAEVFGPIDAGALREIRDLIVTQEPLVETASLDDPLNPQILSIELADGVGAASTARIDIRWSLAGNYAAHYTDNQGRDFRFDCHPKPDAPTRHFHPPPDAPSRPVEPSCITVREASLVTRAILHRWRYAYTNSTFEGINDAENPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ86</accession>
    <name>V6DZ86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_13907</name>
        <name evidence="3" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078077.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76450at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="10"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="186" mass="20684" checksum="2F206A196133A903" modified="2014-02-19" version="1">MVQTESESELDRGDVAPDFELPGADGETYALDDFETDALLVVFTCNHCPYAKAKIDLLNDLAVEYDDLAVVGINPNDADEYPEDSFEAMREAVADGTVAYDAYLRDETAEVAAAYDAVCTPDPFLFGREDRKWRLRYHGRLDDALNPDDEATEFYVRDAVDAVLAGEEVEIPDRPSRGCSIKWPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQA6</accession>
    <name>V6DQA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_00445</name>
        <name evidence="2" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076250.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115195at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="12651" checksum="9D5FADFF2F4ACAE2" modified="2014-02-19" version="1">MDEDEDTVLAILDDEYARAILAHLTIEPMSVDELCTACEMSDATAYRRLSRLQDADLVTEQQEIDPDGHHYKRYVATVETVTVTFGDGGYEVAVTRSKTDPADRFTDLFEGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQB5</accession>
    <name>V6DQB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C461_07094</name>
        <name evidence="3" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="175"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="313" mass="32427" checksum="683E5C61C63E9535" modified="2014-02-19" version="1">MTTFSHVVPKMTIPSLGSLVGLTLAIVAAVLLAVQNLCIRIGTDSGNTSDAVIVVMSVNLGLIGPLTAVLYYPDYGLSAVAVGAFATAGIVGLVLGRVCMFAGINRVGASRTTPIVSASTLVSTVLAVRLFDETLTLPHLAGIFCIVGGVAGIAWQTASTDRPQDSLREVGALLLLPVSAAVFTGVEPLLLRVGLDTGTPILVGLSVMMLTAFIGYTGYRTLHENALPRLFENPQMRWYAGAGLASTIGLLAYFGAIASAPVVVAIPIIHTAPLIVIALSIVLLPQHLEQITWRLVLAAVFVVTGASLVTFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQB7</accession>
    <name>V6DQB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_00455</name>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11068" checksum="0C77434A729EB62C" modified="2014-02-19" version="1">MGGVRRWDAMIVESLLALEPLSMVSVARGVTAVVGLFVATLAYRGYRRNGSAKMRALAIGIALLTAGVFVAVMFADLTGAGNGVVLLVRGLVTVIGLCVVLYAITTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQB8</accession>
    <name>V6DQB8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TATA-box-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Box A-binding protein</fullName>
            <shortName evidence="5">BAP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">TATA sequence-binding protein</fullName>
            <shortName evidence="5">TBP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">TATA-box factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">tbp</name>
        <name evidence="6" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004046033.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38743093"/>
    <dbReference type="GeneID" id="65213164"/>
    <dbReference type="OrthoDB" id="83880at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04518">
        <property type="entry name" value="TBP_archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033711">
        <property type="entry name" value="TBP_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="PTHR10126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="1" evidence="5">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="186" mass="19967" checksum="C599BC9958E0968D" modified="2014-02-19" version="1">MTNPADSIEIQNVVASTGIGQELDLEALAEDLPGADFNPDNFPGLVYRTQEPKAAALIFRSGKIVCTGAKSIDDVHEALGIIFEKLRGLQIPVEDDPEITVQNIVSSADLGHNLNLNALAIGLGLEDVEYEPEQFPGLVYRMDEPEVVILLFGSGKIVITGGKRTDDAEEAVEEIVERIEGLGLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQC1</accession>
    <name>V6DQC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8011" checksum="8DDF17188A28CF0E" modified="2014-02-19" version="1">MVALVALVFAAVPLGGLGALVGTTAGGVVLVAVLVCAVAATVALALPVRLVARTYLIAFEVSTLAGIDPGSAPLPPESAASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQC2</accession>
    <name>V6DQC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spermidine/putrescine ABC transporter ATPase component</fullName>
            <ecNumber evidence="8">3.6.3.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C463_12697</name>
        <name evidence="8" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.31" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076258.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="8"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="355" mass="38974" checksum="9C6DCD22B2B91A45" modified="2014-02-19" version="1">MTTPTTAVQLDGVRKDFGDTTAVDGIDIDLRHGEFFSLLGPSGCGKTTTLRMISGFETPTNGSIRIEGEDVVHRPPNKRNTNLVFQGLSLFPHMTVAENVGYGLKKNAVEADERDRLVEKYLDIVDLSGYGDRKPQDLSGGQQQRVAIARALVNEPDILLLDEPLSSLDRKLRQQMQVELQEIHDRVESTFFYVTHDQDVAMSMSNRLAVMNNGQIEQIGTPKEIYREPETAFVADFIGDTNLLDGVVENTTHPPRLELDAEVDVTVELGEPSTKGEVIASIRPEEVEVTEAGGGAIDGTIVDQYFHGERTNLVIEPHDDSLPELDVAVQGRTDVPDSGEVSVDLNADAMSVYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQC3</accession>
    <name>V6DQC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LysE family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_01392</name>
        <name evidence="6" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076253.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89853at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="210" mass="22117" checksum="DCF40B63477A4897" modified="2014-02-19" version="1">MVTTAFVHGLTLSVGLIAAVGPQNVFVFQQGATQPRLRRSLPTVLTAGVADTVLILGGVLGVSAVVIEFAWLQTVLLGSGVVFLIYVGWTLLSAPATALDSQDETRLGVREQVGFTASVSLLNPHAILDTIGVIGTNALAYASPGRWAFTAACLLVSWAWFLGLAAGGRLLGSSVLSDDRLRYLNVISAGVIWIVALYMAWRLLALVGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQC5</accession>
    <name>V6DQC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine/putrescine ABC transporter permease ii</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_12712</name>
        <name evidence="6" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076255.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97465at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="90"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="288" mass="31190" checksum="10DD5E5848E733E5" modified="2014-02-19" version="1">MSDREKYSWLSQIVGEPGLTESVSVDRIVSAVASYGMWVLTIGVIVFLWLPLSQIIVLSFTENSVLFPLGGVTLQNYVSLFTNEGLLMAARQSAFVATVSASIAALIGVPMGFAITRHTFRGRSILRGLVIVPLLMPGIIMGISILILFRVAGLPSGFFATVLTHSVYGLPFIVLPVIARLAVFDRKLEEGARDLGAGSRSVLTDVTLPIISPAIAAGFIFAWLRSFEDFIRVFFVGGTMDALTKEMYGMVVYSQGTEAMDPMATIIVLIVSIALAVAINFRDILEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRA1</accession>
    <name>V6DRA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4594" checksum="9D2D800CD298B056" modified="2014-02-19" version="1">MPDSASRSSRRTGARRGLREIHSVRPFRRSHLSAAVGVDFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRA4</accession>
    <name>V6DRA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Anaerobic dehydrogenase cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C470_13492</name>
        <name evidence="1" type="ORF">BN903_361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4950" checksum="E6F3CC547C0114DF" modified="2014-02-19" version="1">MNKVDDEADAAAARKIAGEIRFRANVPRVLLTRLTAEDPVVEVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRA5</accession>
    <name>V6DRA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02282</name>
        <name evidence="3" type="ORF">BN903_285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="182" mass="20236" checksum="08FA56CE96285AAE" modified="2014-02-19" version="1">MKEQVNRYQKILVVDDGPQLRELQRLFLEPQYDVETASSGESALDALDPTVCVVLLDRKMPGLTGTETAIEIDRSEHTPAVAIVSANPPETDIFDIPCDACLEKPVGEHDLVGAVEELLSRPLHNPPQREYHALRSKHRALDKSPYGNCYTTPEYKHSVKKLGSLEERIGITDKKQAPVAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRA6</accession>
    <name>V6DRA6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">engB</name>
        <name evidence="9" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076522.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="73254at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="8">
        <location>
            <begin position="8"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="206" mass="23398" checksum="217376E4942FA479" modified="2014-02-19" version="1">MFEDRPDRDAEVVLVGRSNVGKSTLMRELTGHDFSTGGKPGVTRQPNHFDWASESFMFTDLPGFGFMSGVEDEHREQIKTDIVRYLEDNADSILAGVVVLDGKAAVDIIDRHRERGNIPHDVEMFGFLEDVGVEPIVAVNKTDKIDDLDERLDAICDRLGLYPPWQQWSDRVAPICAKRGDIEALEECLRTRFHEHNRDDLLKFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRA7</accession>
    <name>V6DRA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_12116</name>
        <name evidence="4" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076511.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99964at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020948">
        <property type="entry name" value="P_starv_induced_PsiE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06146">
        <property type="entry name" value="PsiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="173" mass="18492" checksum="706BFF8E01E1FD28" modified="2014-02-19" version="1">MADSPPADPSDDPSSPDRTPNPSVAKTRGDRVSDATNRFIHGVELAAAALFALLFGIGVIDLAIQIAESVPTGAITDPNTVIGFIETGLLLLIIVEVYETVVAYIEQSDTRRIVRLVIYTGVIAMVRKVIIYRTTEYSSAEGALFAAVSYTIIILGLVALLYVERSVGNPLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRA9</accession>
    <name>V6DRA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mandelate racemase/muconate lactonizing protein</fullName>
            <ecNumber evidence="2">5.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01674</name>
        <name evidence="2" type="ORF">BN903_366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018849">
        <property type="term" value="F:muconate cycloisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="206" mass="22112" checksum="00A456EC1B9B0AF7" modified="2014-02-19" version="1">MREKAADAVEAGHSVLKIKLGTDRDRELVDAVREAAPDARLRVDANEAWTPKEAVRKADWLADRDVEFVEQPVPAEEPEGLRYVYERSPLPIAADESCVTVADVPAIADRCDIANLKLMKTGGLLEARRVIAAARAHGLEVMCGCMIESNASIAAAAQLAPLLDYADLDGSLLLAEDPYAGIDLPDGEIRLAEQDRAGTGARPTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRB1</accession>
    <name>V6DRB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_12076</name>
        <name evidence="1" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076514.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="126440at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="8807" checksum="A1E801BA39E11DC5" modified="2014-02-19" version="1">MPDEIHLSRVESALEDHAYPADSEALAESFAGTTVLFADGEGDLGDLLADVDQETFESAADAFAALQNVLPIEAVGEPGQSDGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRB3</accession>
    <name>V6DRB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dihydroxyacetone kinase, phosphotransfer subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C464_12120</name>
        <name evidence="4" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076519.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117161at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047324">
        <property type="term" value="F:phosphoenolpyruvate-glycerone phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039643">
        <property type="entry name" value="DhaM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036662">
        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38594">
        <property type="entry name" value="PTHR38594"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
        <property type="entry name" value="EIIA-man"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
        <property type="entry name" value="SSF53062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51096">
        <property type="entry name" value="PTS_EIIA_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="3">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="145" mass="14148" checksum="79E1AA4CC79877EB" modified="2014-02-19" version="1">MVGIVVVSHSERAAEGIAEIAAEMAGDTRIEPVGGDGKGGIGTVPDAIEAAIDAAAGIDAEDGSDAGDENGGDPDGSDPVVVLVDLGSAVMNADIAVELSDAEAVIADAPVLEGAVNAAVAATDASATVESVREQAEAARDIEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRB4</accession>
    <name>V6DRB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongator protein 3/MiaB/NifB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_12026</name>
        <name evidence="8" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29724at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005909">
        <property type="entry name" value="RaSEA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004954">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01210">
        <property type="entry name" value="TIGR01210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Elp3" evidence="7">
        <location>
            <begin position="35"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="344" mass="38212" checksum="ED02F7768898EFC9" modified="2014-02-19" version="1">MMRDIRAERSETYDPTEPTRVWIDEDNTPDGVVNSLTIILNTGGCRWARAGGCTMCGYVAESVEGGSVAHEDLMTQIDACLDHEREEADEPAELIKIYTSGSFLDEREVPAETRRAIASEFADRDRIVVESLPDFVSREKIADFADHGIATDVAVGLETATDRVRHDCVNKYFDFADFEDACAEAAEADAAFDADVGIKAYLLMKPPFLAEPEAVDDMIDSIRRCADVDGCHTVSMNPTNVQRYTMVDELFFEGGYRPPWLWSVAHVLEETADADAIVVSDPVGHGSDRGAHNCGECDDRVQTAIKDFDKRQDPSVFEQVSCDCEATWEYVMEAETSYNMPLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRB5</accession>
    <name>V6DRB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4874" checksum="EF42C4D7CD556515" modified="2014-02-19" version="1">MEIGALTVPLGGEPIEDAVASPDDRGVDVLDRAVFETEPGDAYWAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRB7</accession>
    <name>V6DRB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-formyltetrahydrofolate cyclo-ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_11930</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="12142" checksum="944CF93E61BE07DC" modified="2014-02-19" version="1">MDKQAVRDAVWDAFDEGDQARFPFPPHDRIPNFAGADAAAEQLADTPXXXXXXXAPGRPSTSRSRGCATRTRSSGSTPRKSPRTRSTTRRPSRGSPSTGRRPRPRTSRTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRB8</accession>
    <name>V6DRB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase, TrmH family, group 1 protein</fullName>
            <ecNumber evidence="3">2.1.1.200</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_11976</name>
        <name evidence="3" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.200" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="251" mass="28222" checksum="455B803909C45DFC" modified="2014-02-19" version="1">MVVVEPETPGNVGTIARAMKNFGLSDLKLVDPPELKEDGEAYGFAGHAREDVLPNAEEVTFDEVVENYHTVGTTAITGEDDRSHERFPFKTPVELRESLKTVDAQTAIVFGREGRGLNNEELSRLDEVCSIPAADDYPVLNLGQAATVLLYELRDLTVNETQLPDTEVTRAPEPDVERFHEFFDDFLASTGQRDHVREKNALLMRRLLGRAHPTEREIHTLLGTFRKANTKLEHADHLAAKYDEPVYPQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRC1</accession>
    <name>V6DRC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="5971" checksum="B0FDCC35C320B621" modified="2014-02-19" version="1">MIRTDRRPICGAAARASECLLKARGAPREVAGGGAAGRQRIFDSRWSQSPERSAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRC2</accession>
    <name>V6DRC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5940" checksum="664DBED9287152AF" modified="2014-02-19" version="1">MLSLFGRLWFRGERERYTINPNLSASMISSRPRTADVRNCKRFHRRVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DRC3</accession>
    <name>V6DRC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6144" checksum="1988AE1EF8982F40" modified="2014-02-19" version="1">MKARKLDWAARLLRWLERRRGERFAVLDGRREAADEALEEILGEGFEGDRGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK0</accession>
    <name>V6DUK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
            <ecNumber evidence="2">1.1.1.91</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09953</name>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.91" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077427.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43721at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047681">
        <property type="term" value="F:aryl-alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="341" mass="38429" checksum="59BE3741821665CD" modified="2014-02-19" version="1">MDYRRLGNTGLSISELCLGTWRFGRETNGVVETGREEAHELLDAAAGRGINFIDTANVYGTPHGTSEEYIGEWLDERDREDYVIASKVYFPFDGRGEPGPNDSGLGRKHIRAQVEGTLDRLDTDYLDVYYIHRWDEETPIEETMRALDELVSEGKVHHLGASTMAAWRLTKAQWTADVNDYASFDVVQPLHHAGYYEDVKEYLDVCIDQDLAVCPYSPLAGGFLTGKYERADPDDPEQVIAPDGSRASFDDRFERFYLSERGWKVLDAVREVADELDATPAQVALAWLSGWDEFTCVPIVGARTVDQLDENVAATDLDLSDAQWDRIMDARYDPDGTLWGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK1</accession>
    <name>V6DUK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02979</name>
        <name evidence="2" type="ORF">BN903_187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076640.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92473at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14066" checksum="A62BFA7776FDC817" modified="2014-02-19" version="1">MADIETSTVSEEGYASTSQVGEFDLRIDATDETGPNPNATLVATYASCYLPAFRVGGSQRGEEELGKIQIDASAELDDDDDLESIAFDVHVEADLDDETAADVAERAEGICHVHSALREGLHADISVYPGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK2</accession>
    <name>V6DUK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C437_15034</name>
        <name evidence="1" type="ORF">BN903_173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="304" mass="32626" checksum="DDFC21FB142818FE" modified="2014-02-19" version="1">MEVTMMSRDTSTPNDRKIGQSISRRRLLACSGTALLSGVAGCLGTNTARNGTESPTGSPSPPIDSVFEEIEFVGPNLVVTLAEDHDVDRLNLISPDGGTFEQVTVTEGVTTAEFQILYKSGGSYDTGNYELVAVRGESSDTMSVELRPEISVVDVEPDVDVDDQNSTGRLFVTVENTGTGPTWVYNIGFRNAPYSNAPEVIEGDGVADTRFERPQDPQQEFLQPNTEQRFLKGRGVLIISDDDSISCEGGSIELTVVVQTPHGDIEQPIRADLSGGYHVDDQAAVQHPCENADIELLSGGSNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK3</accession>
    <name>V6DUK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">XerC/D-like integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C483_17338</name>
        <name evidence="4" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="192"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="374" mass="43945" checksum="A6820EB11FB795FC" modified="2014-02-19" version="1">MGPKPMEKIGKAPIVGGTARDYLDERRYTDYYDYKERLLRWLDTMGKNPERAEGYADSTVANVTYKIDLYNVWNWKETGNYGTRLTTDRADAHMMYLIMEGDRYSDTYKDIVQKCLKRVFKYQNHVEGADIEWEPEHTFSQDLSAPRDFLTMDERRAVRDAALDYGSVPAYNGLSPGERDQWRQYLSQRLEKPKKKVVPEDWTKANSWKIPSITWTSLDTGLRPIEVERARVQWVDTKNNVLRIPKDESSKNEDNWTVSITERTGSALERWLDEREYYDEYDDSDALWLTRHGNSYNSSSLRKVLHRLCGIAEIPVENRQMSWYTIRHSVGTYMTREEDLAAAKAQLRHKSPKTTMRYDQAPVEDRRDALNRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK4</accession>
    <name>V6DUK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Monovalent cation/H+ antiporter subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C463_16327</name>
        <name evidence="9" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002758">
        <property type="entry name" value="Cation_antiport_E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34584">
        <property type="entry name" value="PTHR34584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01899">
        <property type="entry name" value="MNHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="267"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="315" mass="34601" checksum="45FC6FC96BB56B04" modified="2014-02-19" version="1">MIGADDYLFGADDYVRVLVEYAERNDADRVVLDPEYTPVGNTTLLQPLEFALSNTSLSVETAPVDRPTRRERFRTEATTGRFVALFGLSLAFYLLLGDPTYWFDAVTGVATAAIVSITLSRVSLDSTPAIPRTPMRILRGLVYVPVLLFEILKANLVVARVILDPRLPIEPTMNRVRVIVGSGLPLMTLANSITLTPGTLTVRARDSDLYVHSLVPWAREGLFDGSLERWTRFVYYGRRSARLPTPRERDDVAILQGDDATEELPIAAADGGRADATDEINTVDATDPSAATDTIDTTDDEDATAPVDGREVIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK5</accession>
    <name>V6DUK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_15059</name>
        <name evidence="2" type="ORF">BN903_178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076905.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97459at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13576" checksum="740F37D8AAE21332" modified="2014-02-19" version="1">MLHETVLIFGVYLVACGIAWILHESAHYVVHSLYAESVTFGVNRRGPYVDAIYDPDAPTFAIRVGSVAPTLLYTPFVFLGIAGYLSIYSLPQLDPVEWSLVTIPLLILTFPTGSDIQSCLEAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK6</accession>
    <name>V6DUK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5331" checksum="7B2C8720590C535F" modified="2014-02-19" version="1">MSVDYLQTETESYSRAAEASQRFVSVSDFYSRNYPASVTKKCGSRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK7</accession>
    <name>V6DUK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2-oxoglutarate ferredoxin oxidoreductase subunit beta</fullName>
            <ecNumber evidence="7">1.2.7.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_02596</name>
        <name evidence="7" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077429.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000009.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43666at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047553">
        <property type="term" value="F:2-oxoglutarate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011896">
        <property type="entry name" value="OFOB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032686">
        <property type="entry name" value="PFO_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12367">
        <property type="entry name" value="PFO_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02177">
        <property type="entry name" value="PorB_KorB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="51"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PFO_beta_C" evidence="6">
        <location>
            <begin position="202"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="287" mass="31326" checksum="ED67F5BBF10B3087" modified="2014-02-19" version="1">MSSDIRFTDFKSDKQPTWCPGCGDFGTMNGMMKGLAETGNDPDNTFVVAGIGCSGKIGTYMHSYALHGVHGRALPVGTGVKMARPDIEVMVAGGDGDGYSIGAGHFVHAVRRNVDMTYVVMDNRIYGLTKGQASPTSREDFETSTSPEGPKQPPVNPHALALASGATFIAQSFSSDALRHQEIIQEAIEHDGFGFVNVYSPCVTFNDVDTYDYFRDSLVDLKETDHDPTDREDAKDVILDNEKEHQGVIYQDESSVPYHEKHGVDEDMSVIPDGAPESATDLVREFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK8</accession>
    <name>V6DUK8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4167" checksum="63A13852BBC72190" modified="2014-02-19" version="1">MGGISTNLYSGEPAFSQSARENILELISTKTGNPIQELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUK9</accession>
    <name>V6DUK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Halar_0028</name>
        <name evidence="1" type="ORF">BN903_197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6891" checksum="568273F823B7D115" modified="2014-02-19" version="1">MTEQVPLKRRATYNHLRSLADEGRLESKQIGGRNTVWWLAESEKPGPRTFFEKNVDDSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG5</accession>
    <name>V6DVG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
            <ecNumber evidence="2">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05719</name>
        <name evidence="2" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.274" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077162.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35652at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="8"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="29707" checksum="496E9E872D8A1EB2" modified="2014-02-19" version="1">MTDAFDRLGYGTYKLAAGEECAAGVAHAIDTGYRHVDTAQGYDNEASVGDGIDRSDVDREDLFVATKLSTDNLSYDDAVETAQASRDRLGVDSIDLLYVHWPINSYDPAETLPALDDLVDDGVIDRIGLSNFEPDQLDEAIDRLDHDVFAHQVECHPFLQQETLREYAVDDGHWLVAYSPIARNRVADVDALREIAASHDATPAQVSLAWLLSKERVAPIPKAADFGHVADNWAAREIELTDEEIARIDALDRGERVVDFEEAPWNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG6</accession>
    <name>V6DVG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase/fumarate reductase, flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02674</name>
        <name evidence="2" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Succ_DH_flav_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="123" mass="14456" checksum="7250FCF9572445C5" modified="2014-02-19" version="1">MTANVNVFREEGRLEETLADLHEAREAYKDVAVSDPSRTFNTDLIHTIETRNILDIAEALTMGALAREEFRGAHWRKEHQERKDENWLKHTLISWNDGEPELWYKPVVLEGENKTYEPKSRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG7</accession>
    <name>V6DVG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5212" checksum="CCEE25A58E5ECD80" modified="2014-02-19" version="1">MRTDINYPTRRLNLRARYAEVERKRRFDSASSEKLAIENEAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG8</accession>
    <name>V6DVG8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04221</name>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="36103" checksum="17F9EE9E311D1450" modified="2014-02-19" version="1">MNPDRSADWTVAVRYSLADGNETAAFETAGDRFRDGDIGPSADLFEGFRREANRNVGRSMSIGDVDREVVVHEDPEEFDVATEEAVAVGELRLTFTWTAFLAQDGENLVLGDALTTPGNETWLRSLESSQTLEVATPEGYTVTGTPSTAVTRLSDGDVIIEGPQTFDGGEPVAIVYGPAGSPPWEMVVAAILLAATLVAGSVVGYRRINAAEAEAGEPVANGDEREARAEARGPVTGPNGGGGPETDAGGSADTDGSEDGTDLSLLSDEERVERLLDENGGRMRQADIVAETGWSDAKVSQLLSAMADEGRVEKLRLGRENLISLPDGEDSEGGDEAERVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG9</accession>
    <name>V6DVG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_05291</name>
        <name evidence="2" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="467" mass="49628" checksum="056A12C24CF57975" modified="2014-02-19" version="1">MNRRNVLQFFGVSSAAALAGCGDSSTVDNESSNGDSESSNVASERIVIRDIEWDWGDDGLDQVTIVVVNKGEYPVQLERAEFTLESPDTDLSRSLNTTLSPGTADKIAISSSQSIKVENLGTQIGTATVETDIGTVSESFPYDPGLPALLTFVSLRPSWDGNTITDATFRVGNLGELLTSVQISATANGEEVATAPTEKIYPGTGRSLVVSDPESLQTATSGEDAELEFTADSPAGQAAGIISQQITDTDLSVDSMSSGWANGQFVELLATLSVNADTDLNPSAQITIDDNKIKNGSFTIQANERLEDLPFYDEASSLGRQAIEPDPYEIRTGGTHEVVLNLELEDGSISASHSKEFDGLDTVFSDIEASFSSPGNGTDDVELSEVKFGVRNDGDVVLRYDSIEIGIGDPSRTDELTSSKGLLPGSSEQEHVRLSNGRAVSPGEKELTISLLYKGDEIERTTTTVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH0</accession>
    <name>V6DVH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="11530" checksum="05CFD37E180B9F3D" modified="2014-02-19" version="1">MRTKHAAASTGRSERSERLKRAARRASPASESERDHERRSAERSEATVFRRYSRLGLRRCSWSKSEPVSFVYDHGWIDAPHQTDRSPRHGQYRKYANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH1</accession>
    <name>V6DVH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4737" checksum="9FE6DD2DA5AFFEBC" modified="2014-02-19" version="1">MADERLTRSGSFCWLISTNREKPAQKHSEAVSCSLSPRSRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH2</accession>
    <name>V6DVH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5967" checksum="56A23ECB29BD8380" modified="2014-02-19" version="1">MPRGATRTLLSGRRRHESRSRARRAVRSGAGPTGPRRRCRCRGRPRRGTARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH3</accession>
    <name>V6DVH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C461_08274</name>
        <name evidence="2" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5323" checksum="1679D7F0B8A5C10A" modified="2014-02-19" version="1">MVPVLGTIAGVFVQFYALVAAAAIIGWTWADVRPIALDETEPEPAERPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH4</accession>
    <name>V6DVH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_05689</name>
        <name evidence="3" type="ORF">BN903_111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077168.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118262at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="15436" checksum="1B84EBF6AACEA666" modified="2014-02-19" version="1">MGNKNKTISFRVNEGAFEALRDIAEERDISLSAVFRDYVDALVAHDGQVRVVPESELEGMGDDGESFPPKIEVPKSFVREHERLELEAEHLREQLDEHKRYVNYLREQLEEGDDEVIHLEDLDGEPDEPSFRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH5</accession>
    <name>V6DVH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8433" checksum="C17E47B0A02F1104" modified="2014-02-19" version="1">MFYFRFLSVTICRLLVHLSHLLAGITAVNSRVSLTSGFRGESIRTGFQQSSSGGDPRRTPRLGEPALPRRGTDRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI0</accession>
    <name>V6DVI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative circadian clock protein, KaiC</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_2353</name>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010624">
        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KaiC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20523" checksum="6EAD3617BC7CE7C1" modified="2014-02-19" version="1">MTAERVSTGISGLDEILDGGLIQGRNVLMRGSPGAGKTILGLHFLSAGIDAGESALYVNMGEPQAYVEEAADAFGLNTDQIQFHNLSPTQEQFSKRNSYSVFESAEVEQPGFIAALREQIDKIEPDRVLLDPITEFRYLAGDKRQFRSGILGLLDYLKEMDATVMLTSQAGGRSPMTICSSSSTPSSHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI1</accession>
    <name>V6DVI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Galactoside O-acetyltransferase 1</fullName>
            <ecNumber evidence="2">2.3.1.30</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13807</name>
        <name evidence="2" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077666.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37174at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="311" mass="35161" checksum="129F4ABFCDD16338" modified="2014-02-19" version="1">MTKRHVSLPDGAEAGVRGFIDEVDERLSSDEDTCEVVRDVLIDLHGDREAWEAWQDGESVSRAERVRLQGYDPCNATLESEYYAEKDEDRFQRSKHLQWLWRQFDATPMADNVEFALRFRQMLGSHLFAECGDNCRFFKGISVTYGHNIEVGDNVVVHDGVHLDDRGKLTIGDRASISDGVHLYSHDHDIVDQTTVRNFHTIVEADARVTYDAMVRAGCRIGENSVVGARSVVQGDVPDHHVVVGSPARSVRVKPGWESAAEELEDGRLPDNQDDREIEYELPDDLDQFDEFGRDLKPPDVENPSPPSTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI2</accession>
    <name>V6DVI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen-fixing NifU domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hlac_0148</name>
        <name evidence="3" type="ORF">BN903_122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077172.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112009at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="2">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="12892" checksum="C0DF5BE71C96C760" modified="2014-02-19" version="1">MSTDATDADNDLRERITNFLRRNFPQIQMHGGSAAIAHLDREKGEVTVQLGGACSGCGISPMTIQAIKSRMVKEIPEIETVHADTGAAAGADGDLGGTSSGGMSPSFPGETTDDGGDDEGPQAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI3</accession>
    <name>V6DVI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6294" checksum="E4565263939F6107" modified="2014-02-19" version="1">MVPVAESFAAKTLTYGLTTGASEVFTASPAILPLIPSLPSKEPSYKHALATNRFKRGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI4</accession>
    <name>V6DVI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C468_05518</name>
        <name evidence="10" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="9">
        <location>
            <begin position="2"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="289"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="351" mass="37996" checksum="4CC0CF7434C96F1C" modified="2014-02-19" version="1">MPPGEVALRIAAGVFLILINAYFVAIEFGLTRLRQYPESEMDSPGLRRAWEMTDDLEFYLTTCQIWISGTSIALGIVAEPGLAAVFAPVFENTTLASAGAGSLLAFFLINMVHLTHGEQTPTYLGVERSKQVAEYGARPLYWFAWLISPLIKFGDRVAKATLRLFGVEMTGSWTETEGEVLETRAQLRTRLGSMMEEVDLPEERRQEVLAALDVDEVAVGDVMTPADEIVSLSTTASAEANLDRISDTPHARFPLVGTDLTAFEGIVYAPSIVSHFEALRAGETTFAEIAAPPMTVSAATSVSDAFDQFQAERQELALVIEDGAVVGLITATDALEAVMGQLEDPLDAGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI5</accession>
    <name>V6DVI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11660</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077690.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="131484at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6936" checksum="266317D6DC1A98E0" modified="2014-02-19" version="1">MNRAEIDTDDLLKLVLLLVVVWLLVEIVETVLDIAFWVFDAIPTLIGIALVVVIALHLADRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI7</accession>
    <name>V6DVI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I protein</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C462_10213</name>
        <name evidence="4" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_II" evidence="2">
        <location>
            <begin position="2"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="3">
        <location>
            <begin position="59"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="1">
        <location>
            <begin position="181"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="255" mass="27373" checksum="B6794ED14302BDD0" modified="2014-02-19" version="1">MTFGGDSPEPSAEHLEALAERVTDPESDVDLGIANDGDADRIAVVTPERGVLDANLFYAACYDRLLESDSGPAVRTVSTTFLVDRIAEAHGEEVYETPVGFKWVAEAMGEHDALFGGEESGGFTLRGHVREKDGVLMALLAAATHAAEPFDARVDRLLDEHGHIAAGKVSLDCPDDRKAGVLDELEDHIPESVCGSPVAKVVTLDGFKLLLENGSWLLVRPSGTEPKLRVYAEADSDEAVEELLAEGREIVEPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI8</accession>
    <name>V6DVI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4994" checksum="6052DFD70F03E36F" modified="2014-02-19" version="1">MGSRVPRGRGDNRVIGRSRSGIRRRGRSTIHRLSLGDRHRRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVI9</accession>
    <name>V6DVI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5799" checksum="83976ABB6A7F0CD8" modified="2014-02-19" version="1">MSHRRSRRSSRYSPRARPRRPRRRSRGSVCGSSSSRPDRGSSCVLGLPKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ0</accession>
    <name>V6DVJ0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase sliding clamp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Proliferating cell nuclear antigen homolog</fullName>
            <shortName evidence="3">PCNA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">pcn</name>
        <name evidence="8" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077693.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70433at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PTHR11352:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCNA_N" evidence="6">
        <location>
            <begin position="6"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PCNA_C" evidence="7">
        <location>
            <begin position="163"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="247" mass="26845" checksum="02F2CD27B4E3A81B" modified="2014-02-19" version="1">MFKAIVGASTFQDALDSVSVLVDECKIRLNEEELSIRAVDPANVGMVDLTLEAAAFESYEADGGVIGVNLARLEDIAGMANSGDLIHLELDEETRKLHIEIDGLSYTLALIDPDSIRQEPDIPDLDLASEIVVEGAQLDRGITAADMVSDHIRLRVDESDEAFYIEAEGDTDDVNLKLDREDLIALTAGAADSLFSLDYLKDMNKAIPSDAEVTVELGEEFPVKLHYGFAEGLGNVTFMLAPRIQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ1</accession>
    <name>V6DVJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6374" checksum="AAB5712108C5DA21" modified="2014-02-19" version="1">MDLVFRSKGAIRFGSLLSEAAPASEDGAVDRINRVYTNRAEKCGMIHARRVTTARGGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ2</accession>
    <name>V6DVJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
            <ecNumber evidence="8">1.8.98.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_09863</name>
        <name evidence="8" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.98.1" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076980.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44343at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051912">
        <property type="term" value="F:CoB--CoM heterodisulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="289"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="371"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="729" mass="80256" checksum="E4F489589306DEC7" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ3</accession>
    <name>V6DVJ3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LUD_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07134</name>
        <name evidence="3" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077696.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90418at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="2">
        <location>
            <begin position="27"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="23834" checksum="EA126769FBFA266C" modified="2014-02-19" version="1">MSQQKADYADDAEIDAELDDIPDAETVEETVANLEERGFDVIVVDDADEALETVKSQIPAGVSVMNGHSTTLEEIGFDEFLSEGDHDWESLPDRIWGIDDDAERQTARRESQTADYFLGGINAIAGTGELVAADLSGSRIGAYPFAAGNVVIVSGVNKIVPTLDDAFDRLESVAYPLENERAQEAYGVESAIAKQLVYRRETEEGRTTLVLVRERLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ4</accession>
    <name>V6DVJ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="8097" checksum="770E2F041CF562CE" modified="2014-02-19" version="1">MTEERSERLAVSQLGLRRSAWEKQSRRKRPCRSEPLALHQLQSRPLRIERLGLRRSRSRQLRHDKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ5</accession>
    <name>V6DVJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3899" checksum="92BDC9BDBA8212C8" modified="2014-02-19" version="1">MSDQGCRVKSVGSPAGRYETVTATDTTAEAPATTKPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ6</accession>
    <name>V6DVJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5052" checksum="415BFCC6FB8C4ACE" modified="2014-02-19" version="1">MYGSRGVRRVGTPPSDASERLPEVRDGSEVNTYIRQPSVSTSDEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ7</accession>
    <name>V6DVJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphate ABC transporter, ATP-binding protein</fullName>
            <ecNumber evidence="8">3.6.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pstB</name>
        <name evidence="8" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.27" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076984.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78752at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="33"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK39268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="30752" checksum="1D5F2954986D8B45" modified="2014-02-19" version="1">MSESDTSPKIQTTIETGDEDRGKAPLDAEETVIEARNLDVYYGEEQALNGVSMAINEHDVTALIGPSGCGKSTFLRCINRMNDMIDVCRVEGDVEFNGKNVYDDDVDPVALRRKIGIVFQKPNPFPKSIRENVAYGLKIQGYEGDVDERVEESLRRAALWDEVKDQLGSSGLDLSGGQQQRLCIARAIAPDPEVILMDEPTSALDPVAASKIEDLIDDLAEEYTVIIVTHNMQQAARISDRTAVFLTGGELVEYDDTAKIFEDPEEQRVEDYITGKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ8</accession>
    <name>V6DVJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FeS assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sufB</name>
        <name evidence="4" type="ORF">BN903_142</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="3">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="441" mass="49430" checksum="9F7F7C00B667005C" modified="2014-02-19" version="1">MSSQQDDLQETDTEARFEFKKEEKSAFQTEKGLTEETVRVISEDKDEPEWMLERRLRALEQFQEMPMPTDWPGQPDLSEIDIDEIVPYIRPDIDVRGGAENWEDLPEEIQDTFDKLGIPEAEKNALSGVGAQYESEIVYQNMQEQWEEKGVIFCDMDKAVRDHEEIVREHFMTKCVPPSDNKFAALHGAIWSGGSFVYIPEDTTVEMPIQAYFRMNSEGMGQFEHTLIIAEEGSEVHYIEGCSAPKYSAFNLHSGGVEVFVGEDAHVQYSTVQNWSKNTYNLNTKRAIAEKGGRMEWISGSMGSKATMLYPSTILKGRGASDNHITIAMAGEGQDIDTGAKVYHNAPNTKSTVESKSIAKDGGRTNYRGLVHIADGAENSSTAVECDALMFDNESTSTRCRTWRSTSRRSTSPTRRPSARSATRTSSTSSRAVSTTTTRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVJ9</accession>
    <name>V6DVJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hbor_09680</name>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7066" checksum="F9335E7AC30542BE" modified="2014-02-19" version="1">MSGPEFPSSWSDPRYIAAIVSVIATGALYFYAGLTQSGLTIEEITLVIFAILLPTSIAYEIARRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK0</accession>
    <name>V6DVK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4945" checksum="FAEDD8EB87B0A5DE" modified="2014-02-19" version="1">MPPSPPSPSSTCSARXLTTNSMSIRNVLTYVRRDGGRTVDRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK1</accession>
    <name>V6DVK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_09609</name>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9838" checksum="4ABF3738B61068BB" modified="2014-02-19" version="1">MYMMMLRRVLGDGFTVWDKSAALEFIEPGRDTLYAEFELPRSETEAIRETLDPGESTDREYLVSLVDESGTVHAACEKTLYVRRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK2</accession>
    <name>V6DVK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_08805</name>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077704.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117849at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10765" checksum="DAB7F05DE9B83233" modified="2014-02-19" version="1">MNHDRIHAREPSHHVDRWSVGVIESIGERDGHCVVTVRPVSEKGDETSDTEPGSGGDDRSVELVITFAVRDLFVGRLAIADDESPVGERVWYRKRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK3</accession>
    <name>V6DVK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6474" checksum="8C30E75DE133EBCB" modified="2014-02-19" version="1">MCRPRGWGFGGVRVDQRFISNYVSPSGWGFGGVRVDQRFISNYVSPSGWGFGGDRSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK4</accession>
    <name>V6DVK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lycopene cyclase domain protein</fullName>
            <ecNumber evidence="10">5.5.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C467_11475</name>
        <name evidence="10" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.19" evidence="10"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077706.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90912at2157"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045436">
        <property type="term" value="F:lycopene beta cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016120">
        <property type="term" value="P:carotene biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017825">
        <property type="entry name" value="Lycopene_cyclase_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03462">
        <property type="entry name" value="CarR_dom_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="247"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="276" mass="30053" checksum="E6A4333A17B2C0EB" modified="2014-02-19" version="1">MLPTLTYLQFHLVFSLPVLALLWYLAPRYEAVRQRRATVGIAILVAIAYLYTTPWISYMIRQGAWSYADGAVLVRALSIPLGEYLFFTIQTVVTAFALHLIGFDPTFREGDFDRGPRVAGVLAGVAMVVGGLWLTTLDPSYLYLGGLVAWVGPVVALQWAVGGGYLVRTPRMWLAATLLPAAYFWVADRIAIGMGTWSISAEYTTGVAVLGLPIEEMLFFAAAGVMTVNGLVLFEWVLDWNDRRGSVAESVPSGGAEHDVPGPEPPADPDPDVVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK5</accession>
    <name>V6DVK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4277" checksum="BEF7FA4B70A85734" modified="2014-02-19" version="1">MSDHSPQPDRMRRPPRSAVGPRPPAATPFPRGGELIIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK6</accession>
    <name>V6DVK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4775" checksum="17D49718901D6131" modified="2014-02-19" version="1">MIIRRLSDIKTTMRNIRTFIAGFYGKRCDRIGRLLCQLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK7</accession>
    <name>V6DVK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_15707</name>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077716.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124553at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="8890" checksum="41057F37F8C9CA85" modified="2014-02-19" version="1">MLTAMVALTLFGLTLLGATFVTAALQSRGRLPFGVPEGVYVSVSIGAMSIVAQSLVGSDWETIAILAVGTLAWATGYETARGADER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVK8</accession>
    <name>V6DVK8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DZANK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_04026</name>
        <name evidence="6" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DZANK-type" evidence="5">
        <location>
            <begin position="62"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="118" mass="12502" checksum="CEB834E6F357F8A3" modified="2014-02-19" version="1">MPRPAPGNAGDINVNVTLDAPNAGPDEDEEAVSVTRETADDAEPSARKTSESPGAKPRENVCGGCGENVPSDHVYCPNCGEKQSHRAFCECGDELRTDWAFCPGCGRRTPAADVLNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYS0</accession>
    <name>V6DYS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_10473</name>
        <name evidence="1" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004597591.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="GeneID" id="55594927"/>
    <dbReference type="OrthoDB" id="105261at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12858" checksum="63DD75ACDB1244AC" modified="2014-02-19" version="1">MVGDDLITVLGNKYNTDILTATGDAKSAQDLSDQLDVPIATCYRRINELEEADLLELHDRPLSDEHRRVKVYRRKVDGVEVDFRDGLTVEVEERSAVKNRLDDVWRDLSSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYS3</accession>
    <name>V6DYS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4458" checksum="1BB32076B9CE8F2E" modified="2014-02-19" version="1">MAGIGIRIVHRRERTGHRRGSGPATRGGRTETIVKVFTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYS4</accession>
    <name>V6DYS4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C471_06935</name>
        <name evidence="6" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Archaeal flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the archaeal flagellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077909.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="94462at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097589">
        <property type="term" value="C:archaeal-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35903">
        <property type="entry name" value="PTHR35903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01917">
        <property type="entry name" value="Arch_flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0974">Archaeal flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="197" mass="20473" checksum="95EF03CB7533E190" modified="2014-02-19" version="1">MFETILDEEERGQVGIGTLIVFIAMVLVAAIAAGVLINTAGFLQTQAEATGEESTAQVSDRLQVVSQSGNVTDGNSGDRVVDQLNITVAQSPGASNIDLNETSVELIGDNGQETFQLSADQASIDIYTGEDGDVVLTDASDRADVGIDLNTTNSGIYGVLEGGDRLSVTFTTPSGATTTAELRVPTTLTSEQSSVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYS7</accession>
    <name>V6DYS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4411" checksum="EACFA9B0DBD9DAB7" modified="2014-02-19" version="1">MKSSSSGSAGSASSSLMGRGSARRKIGVAGGRAAARWLPRCSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYS8</accession>
    <name>V6DYS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain-containing protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_08061</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000026">
        <property type="protein sequence ID" value="CDK41021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="510" mass="56000" checksum="4B9F62386A4FF3D9" modified="2014-02-19" version="1">MRGRTEDFIPARRRYLAMRFSRDRRGQSVVVGTVILFGFLILALSLYQVQVVPQENAQVEFQHFEEVRNDLVDLRAGVLTAGQADTPQFKSIRLGTTYPNRLFAINPPPPGGTLRTSDAYNVTIANGTETITIPSRFISYSPGYNELSRTPTRYDNSVLYLDGREQGEDIVVIEDQSLVDDGTVRLTVLQNEYRRSGTQRATVEIYPTNSTASDGIPTGEVNITIPTRLNASTYWDGAIGDQSVYTGVEDDRYADGVHGLTLQADSDDTRVNTVGIQGSPNEGPVRENVRSPSAEDPGDDPTDDISMRVDDLTDRRSNSPEFYVSYDYGGQFDEIEVSATSTDSSARVTRSLSSGRSGVSLSPGFGNGQEFAVTVRAIRGGQTVDQRTIYTFADTQNPIENDDLSRSDSASIEDYTIEDRSNNNNDVRYRFRYDVSQTGSFSEGLFSVLNRNGNGASASRSTTDRNVNNFRVEPGDGTNTPYKVSILVIDGNGVVVDSRIVTDTADGTDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ41</accession>
    <name>V6DZ41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphonate ABC transporter, permease protein PhnE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnE</name>
        <name evidence="6" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078006.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61191at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017797">
        <property type="entry name" value="Phosphnate-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30043:SF1">
        <property type="entry name" value="PTHR30043:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="107"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="322" mass="34781" checksum="FF71D41E598DC568" modified="2014-02-19" version="1">MSHDDAVRDRYKAIVLARRVRALVFGVGLVVLAGLFYYALTSVGFFEANIPRYLPNFLNALRDFFPFLTPGFPFIDPSGFAAYWSFITEQNLIWGGFGGDTPLLGEAGITLAMGFAGTVMGFPLALLFGVLGSGRVTPFPFNFIFRGLMSSIRAIPALVWGLIYIPLGGIGPVTATLAIATDTVGNLGRLFTDELEEIEDGPIEAMETTGANKPQLITFGMLSQVTTPFIAWTLYIFEINVRIAVSLGIIGGGGLGQVLSVQQGLFRFTNMMATILVILVLIISVEIVSQRIRSALREGDEAQGIVALLLGFPQRMAEAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ42</accession>
    <name>V6DZ42_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C473_01928</name>
        <name evidence="5" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078036.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58376at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="66"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="78"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="448" mass="50058" checksum="7FCA1B6D0EE34DE7" modified="2014-02-19" version="1">MVDGDDQQSLSQSIKGRLQEGVQNSVFRDKGLLDPDAVIDEDRIVGRDDQLDDIITYLRPAVQGNRPPNMLLYGPSGTGKSLIINAVCQQVLELANAQDDRFGVIKTNCQTIKSHDRAVYRLVENAANEADVEIGVPQSGVSTDQKLNRFYEILSNNFDSVIIILDEVDLLVGRQRDPNDEPAYSKLLYQLSRASQLGQIEGHVSVAALTNDPRFMENLDGRAESSFNPQDVVFSDYDADQLQSILKRRRDAYRDGVLEDGIIPLSSAFAAQDHGDARKAIDLFRKAGEIADREGEDMVHEGHVRDAQKEAERDRTLTQMQGLSTQKKLSLYATAIVPVYSQRNLNAVPSTVAYRVYQYLTDLLDADTKSRDSYLRYMSEAETYNFVTSEKRGRGYGSGVHKEYTFVDDPGVVAETLRADIRIEEADNEGDLIKSVVNAQIDNFFEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ43</accession>
    <name>V6DZ43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_08536</name>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000043">
        <property type="protein sequence ID" value="CDK41151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078492.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000043.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58391at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="PTHR12150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="288" mass="31020" checksum="271AFA809DD19CAD" modified="2014-02-19" version="1">MRTEDGLTICVPSSLVREAEDDREATRKLGYVARAAAVFRADRLVVFPDREGDGRRGGEYVRTVLGYAATPPELRKDLWGQRDELRYVGVLPPLRVPWRTGSTPSGGESKTQGLVTEVGPEGRVRVNSPLREHPISLLVPSDMEVEQGERVTIRVSSREPVRARIAGKPEEGFQVVAADLSEALAGDGLAVATSRHGAELSVSRLGDLVSDARKAGGYTVAFGAPERGLPEMLGLSPDRIRAAVADGRSVEPDPGFDLWLNTIPAQASEVVRTEEALFATLGSLTLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ46</accession>
    <name>V6DZ46_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">OB_aCoA_assoc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14219</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000046">
        <property type="protein sequence ID" value="CDK41156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002878">
        <property type="entry name" value="DUF35_OB-fold_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01796">
        <property type="entry name" value="OB_aCoA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="10071" checksum="31A27C7649FE0308" modified="2014-02-19" version="1">MCPECGTADLSRESLDGTGTVETYSVVHVPSPRFADDAPYATAVVDFGPTRLTGVYREGGDAAPDPAIGDRVTVDVGERVTDGERLVVFRPANEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ47</accession>
    <name>V6DZ47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7541" checksum="3F4CEE027B3EB1AC" modified="2014-02-19" version="1">MISTDRTVHLVSLSHAEPSSETCRVPCGPAAYSSPHGLPNRVPRTRAGSCSGSGDRCMTPSGLLVVTECGTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ48</accession>
    <name>V6DZ48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15554</name>
        <name evidence="3" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078018.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26597at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="433" mass="48803" checksum="0020F16F8E165C8C" modified="2014-02-19" version="1">MTARRSVETPIEDTFTKYLTDKGKGDAGEEGAYRADADRELHRFRRWCLGKTADPANATPPESWAGVVDDDTVRFVDLDTTVFSDYARYLSTAGYAAGTVLTYYAHVASWCGWAHAQGYLPRHYARESDAEDPLPENDGRRPGDQQAWEPLHRDLITQFVDRRVSETFDELGAIEVPHADRGDPESETWQAKQQARFKAYQRCREQALVYVVAYTGLRGSEFLSAPKEDREGRNGIRWRDVSFADSSVTVFRKSREWKEASLPEPVITPLKRYAEVLDVPESWPVFTTLHRPSLASHVTEGLADAGLDDDEIERVRAGAPDLIVAAEHDLNAPKPLTTDGARSIMERLWNDDALAERRDELDLSLDGDYLELHGGRRGVGEVLVRQFGYAAAARYLDNSEEQVRDAYQHIEAAERADMATEAFSQTDQRVSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ49</accession>
    <name>V6DZ49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C468_04871</name>
        <name evidence="3" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078043.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21452at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011579">
        <property type="entry name" value="ATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004256">
        <property type="entry name" value="DUF234_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01637">
        <property type="entry name" value="ATPase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03008">
        <property type="entry name" value="DUF234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="DUF234" evidence="2">
        <location>
            <begin position="310"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="464" mass="53175" checksum="C0FEAA4B55D3E69E" modified="2014-02-19" version="1">MTDFVNRSEELERLHDLFDSETADLAVVYGRRRLGKTRLVKKALEGRKNAVFYQARQKTRELQLEQFVEAAANTFPGIEDIRPDWERLFRYLGDQNAIVVLDEFPYLIEQDESLPSVLQALFDHEFDESAPTFVLVGSSISMMEEATLLGDSPLYGRTSLTLDIRELSFDAATKFLPDNVTADEAVRAWSVFGGVPYYLEELDADRSLGENIQQTVLHRHGSLRNEPEYVLRMELTEPTRYFSILEAIAGGATSRNGIAGVTGIDYNQLSTYLDRLSRLRLIERHVPVTEKPERSKRSQYRLRDPLFRFWFRFLSGSADRYDQFGEEAYDRLVDPELADFVAPAFEQLCCEALWTLYDDTPIVNVGQWWYQDHEIDVVGLTDEDTLVVGECKYQASPLDYSALASLETHVGELRWQPSDGSTRTVEYALFSRSGFTDSMYDAARERDNVRLYTIDDVVTALGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZP0</accession>
    <name>V6DZP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nitrate/sulfonate/bicarbonate ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_09476</name>
        <name evidence="1" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078173.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78272at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="341" mass="36194" checksum="AE516244A89C7540" modified="2014-02-19" version="1">MYESTRTASRRSFLAAAGGTATVGLAGCLGGGGGGLDELTVAHMPIYPDLQWYVMEGEGYFSEIDAEVSGQEFGNGPAIVQALGGGDIDVAMFGIVPAMIAIDNGIPARVTAANIREPMGIMAESSFHETFEQQGGDAFATWEAEQGEPFTFGTFPQGSVPDVLLRYWLRDVGVDPESNDSVEIIEISGASSVWQAIANDEIDGTSIMEPVPTIAQAEGSSVTMLRTAAEVLPGQPAAVTLMSDAVRDSPLAAQFLEQHVRATEFIGEEPDATAEHVNEGIGMPVDRARNALDSPLSNFITDPNEITDATQVFSEFAAGNDQIDEQLSTDEIFDLEVYDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZP2</accession>
    <name>V6DZP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein Hsp20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_12872</name>
        <name evidence="5" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078199.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98354at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13553" checksum="6E97ED2F0955D567" modified="2014-02-19" version="1">MSALRDALRDLPDAVFADLLESDEGYILVIDLPGATAETTEVLVEDGRIEIEGRREKAVPEGFEYVREDRPLFLDAELPLPNDADGAGADAETDRGVLEITLPKRDRDVSRTIPVDDADDEGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZP7</accession>
    <name>V6DZP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_13687</name>
        <name evidence="1" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5916" checksum="AE2DA69AC39DF4F1" modified="2014-02-19" version="1">MTDESTDAAVERFLDRAASAFDDYDQGYADADATLATLRTHVDELSASVEETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZP8</accession>
    <name>V6DZP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
            <ecNumber evidence="2">1.1.1.317</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10281</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.317" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078206.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43721at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="325" mass="36877" checksum="B3B3DCB6A26983D3" modified="2014-02-19" version="1">MEYTTLGSTGTTVSKICLGCMSFGDSDWREWVLDEEEGKELIERAIDLGVNFFDTANMYSNGESERVLGDALDGYDRDEYVLATKGYFQMDESNPNSGGLSRKAIEQELEHSLDRLGVDTIDLYQIHRWDDETPIEETLAALDDAVRRGDVRYIGASSMWAHQFADALHTSEREGYERFAAMQNHYNLAYREEEREMLPLCEKENVGVMPWSPLARGYLTRPHEDVDATLRGETEEHLYAHPYREGGGLAVNERVEELAAEKGVKMAQIALAWLFHKEWVDTPIVGTTSVEHLEDAVEALDIDLSDSDIEWLEAPYEPVRVSGHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZQ1</accession>
    <name>V6DZQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4595" checksum="84E818E0A932B3EE" modified="2014-02-19" version="1">MDISPTGLRGFGECGSARRPAFGTPGNRIGTQLSERVRGSVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZQ3</accession>
    <name>V6DZQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12817</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078209.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="5988" checksum="EE40DB43DDA2D3C4" modified="2014-02-19" version="1">MRDTLGIEGIVGLLVVFAGIGILTLHDPVVAGALMVVLAGLALIAKGLADTVMRSFGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZQ6</accession>
    <name>V6DZQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4925" checksum="BBA8DE0C127FB512" modified="2014-02-19" version="1">MSEGRSGDRGDPDPLIAAFEAGYESAGDPDVLDRLRDVADRGRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZQ8</accession>
    <name>V6DZQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AsnC family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_12787</name>
        <name evidence="5" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078212.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97695at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="16922" checksum="11D4F2FEE0ED66E0" modified="2014-02-19" version="1">MTYENLDAKLINSLLSNGRASLRSLGDELDVSVTTVSNHLRDLEEEGVIRGYTPVVDYDKLGYDVTAILQLKVEGSALPDVTEKLRQEKQMVSVYEVTGDYDVIAIGKFTDTDGMNDQIKSILTDADIRESNTSVVLNAVTENAQFDLDVDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZR2</accession>
    <name>V6DZR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_14237</name>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078219.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74434at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="235" mass="25709" checksum="F3CD7311A0C3A34B" modified="2014-02-19" version="1">MADTILVPLELPDPEPLSPVLIEDLSSLSVVVLGHYDLPEQTPVRSAREQFGEAAQATLDAVAERFVDAGASVRTRLVFGKDRAAAIRQVAAEEGCAAELDPAPTEGIARILVPLPDVAEFDRLPRFIRVLSEDSIQEITLFHVVEGAERRERGETVVSETRERLIEDGFDAGSLDTLVVEGDGHDEEILRIAAEYDAVVMYEPESTLSDRVFGTLADRIADETGDPVILVNRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZR7</accession>
    <name>V6DZR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10266</name>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="10209" checksum="58363807C5CE63C0" modified="2014-02-19" version="1">MPQTYQISITVVAVRSHKLMPGLAMVPDMTASSLALAGLAAPAQAALLGSQVGQLLVALVAVALVVIVGKFVLKLAWRLITIGIVVVAAFYLLSTLGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZR8</accession>
    <name>V6DZR8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L19e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rpl19e</name>
        <name evidence="9" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078225.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109335at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01418">
        <property type="entry name" value="Ribosomal_L19e_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_L19/L19e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_L19/L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_L19/L19e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_L19/L19e_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033936">
        <property type="entry name" value="Ribosomal_L19e_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015973">
        <property type="entry name" value="Ribosomal_L19e_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015974">
        <property type="entry name" value="Ribosomal_L19e_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="RPL19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="PTHR10722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="SSF48140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L19e" evidence="8">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="47"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="17420" checksum="896C52F22AF16C87" modified="2014-02-19" version="1">MSDLKAQKRLAADELDVGKGRVWLDPEAQEEIADAITREDVRELIEQGTIRAKDAKTNSRGRARERSDKRSYGHQSGAGTRKGKSGARQNTKDDWKARIRAQRARLKELRDEEDVLDASEYRTLYNKASGGDFEDVARLEAYIRTQFGYEVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZS0</accession>
    <name>V6DZS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12822</name>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3930" checksum="3A00B1A115FD3CFE" modified="2014-02-19" version="1">MLGAWAVGMGLIALYVGLVGLGYEQAIPRLRRLANGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZS3</accession>
    <name>V6DZS3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C470_10500</name>
        <name evidence="4" type="synonym">rpl5</name>
        <name evidence="8" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078229.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97230at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_A">
        <property type="entry name" value="Ribosomal_L5_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022804">
        <property type="entry name" value="Ribosomal_L5_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="6">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="7">
        <location>
            <begin position="66"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="174" mass="19048" checksum="503D41BAE65552FD" modified="2014-02-19" version="1">MSEADSAANEMREPYLEKVVVHMGVGQGGEPLADAEEIIEEITGQQSVRTTSKRTIAEFGIRKGDPIGVKVTLRGEDAHAFLETALELVEIGRSQFDDTGNLSFGVEDHTDFPSQEYDPNTGIYGLDVTTTIVRPGYRVSKRDKATGTIPARHRMTAEDAAAFLETNFNVEVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZS5</accession>
    <name>V6DZS5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating)</fullName>
            <ecNumber evidence="4">1.2.1.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">gap</name>
        <name evidence="14" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">AJ67</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glyceraldehyde 3-phosphate + NADP(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10296"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.59"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.59" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078210.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57885at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047100">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="13">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="9">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="9">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="27"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="11">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CDK40843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="350" mass="37343" checksum="88129787F1DC4CE0" modified="2014-02-19" version="1">MSKSHLAAGDDVSDDEVVRVGLNGFGRIGRNVFRAVLESPRIELVGINDVMDFDDMGYLAKYDTVMGRLEGVERDGEELTIGGTSVPLFNVQDPADLPWDELDVDVALECTGIFRTRDDASAHLDGGADTVIISAPPKGEKPVKQLVYGVNHDEYEGDDVISNASCTTNSITPVAKVLDAEFGIDAGTLTTVHAYTGSQSLIDGPMSKRRRGRAAAENIVPTSTGAAGAAQEVLPQLEGKIDGMAMRVPVPTGSITEFVVSLDEQVTEEDVNAAFRDAADSGPLAGVLGYTDDEVVSSDIVGLPFSSYVDLQSTNVIAGGKLLKILTWYDNEYGFSNRMLDMAAYVHDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZS8</accession>
    <name>V6DZS8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="4" type="synonym">rpl22</name>
        <name evidence="8" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="4 6">This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078236.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103467at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_A">
        <property type="entry name" value="Ribosomal_L22_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_L22/L17_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="PTHR11593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="154" mass="17101" checksum="B26FAF344AD962F0" modified="2014-02-19" version="1">MGINYSVEADSETTAKGMLRDRPISVKDSKEISREIKGETVADAEEFLREVIDEETSVPMRQHNAGAGHRSDIDGWDAGRYPEKAAKDFLKLLENVRNNADEQGFDGEEMVIKHVAPHKVGERPGRNPRAAGATEWNTTLADVELIIEEPEADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZS9</accession>
    <name>V6DZS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_08401</name>
        <name evidence="3" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078217.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118830at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="246" mass="26727" checksum="F65A825FB49239B0" modified="2014-02-19" version="1">MVSPARVDAITDIAYGALIAVSIVLIATTQMNTVAMAFGIGVFASYVIHVVWKMARFDPDWMTREVADQVGKQVEESVGETVDKEVEKTVGETVNKEVEKTVGETVSKEVEKTVEETVGEKVEETVSKEVEKSVGETVNKEVSGVADDVSNTVSEEVTGKVEETVGETVEKTVEEKVGETVEETVEKTVEEKVGETVEEAVEETVGETVEKTVEETVEKKVEETVDEKVDADDDTEASGNGRRDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQX0</accession>
    <name>V6DQX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Halar_1479</name>
        <name evidence="3" type="ORF">BN903_160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334862.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103133at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="12847" checksum="98C270F209D486C8" modified="2014-02-19" version="1">MSKPTVLLADDEKDLADLFALYLDDHYDTRVAYNGEEALEKLDSSVDVILLDRRMPGYSGDEVLAAVRKEGWDCPVIFLSAIAKDADRENSADDYLEKPTNRDELVEIVKKNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQX1</accession>
    <name>V6DQX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4187" checksum="3BAAC8DBCFE56CAE" modified="2014-02-19" version="1">MTTTSADAELTLGVTTGNLMKHGVRVRSVRSARIDRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQX6</accession>
    <name>V6DQX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01352</name>
        <name evidence="2" type="ORF">BN903_279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5879" checksum="687E8231AC7F48AE" modified="2014-02-19" version="1">MLEPGEFAVVPRGTEHRPVAEPEAEILLFEPSETRNTGDVETDETVTDIEPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQX8</accession>
    <name>V6DQX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_12247</name>
        <name evidence="2" type="ORF">BN903_170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075867.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124778at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="11112" checksum="5BE0AC715842B139" modified="2014-02-19" version="1">MYDLTGFQRDLLYVIAGLDAPHGLAIKDELEDYYEKEIHHGRLYPNLDTLVEKGLIEKSQRDRRTNEYTTTRRGTREIKARVEWEDQYIDHDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY4</accession>
    <name>V6DQY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5478" checksum="B7C76418C4CB0A34" modified="2014-02-19" version="1">MSTITDKELCVCRDTEERMRSTCPQCGGSVTREHGSLGCLACGYTPNHGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY5</accession>
    <name>V6DQY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="5005" checksum="0D0017659483AE21" modified="2014-02-19" version="1">MLLRRGDRALVHISPYTLRRLKPFTSQIGFEKCYHASPNQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY6</accession>
    <name>V6DQY6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5615 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_2989</name>
        <name evidence="2" type="ORF">BN903_180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041049">
        <property type="entry name" value="DUF5615"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18480">
        <property type="entry name" value="DUF5615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5615" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="11054" checksum="CA47D97AF0A696A5" modified="2014-02-19" version="1">MPPAIVSALRGEGHDVAVVGDDVELGSEDTVLLEYARETDRLILSEDTDFRGADPELNVEDHPGIIACDTAASAGEIAAAIRRIEMYTDELVGTVLYVPGNWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY7</accession>
    <name>V6DQY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01372</name>
        <name evidence="2" type="ORF">BN903_277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076371.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88066at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20691" checksum="8C17C50954A1FC55" modified="2014-02-19" version="1">MDDTPLHERMRRYETLASEARKATKKRDKMGKAIGRRLATSVTDAVEREGANVEVLGQSADGDRYRFAARLDRAALVAALTETLPDGFVVSHVNDDGTLSVEWTGDERTPSKRQHGAVLKAVIAEEMVVDDDGLVESVPTRDRVLARAVELGLDEDDAAARLDRLATLEVVDLDDGYVYPDENFSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY9</accession>
    <name>V6DQY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-glucuronidase</fullName>
            <ecNumber evidence="2">3.2.1.139</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_00960</name>
        <name evidence="2" type="ORF">BN903_246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.139" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046559">
        <property type="term" value="F:alpha-glucuronidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037054">
        <property type="entry name" value="A-glucoronidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011099">
        <property type="entry name" value="Glyco_hydro_67_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07477">
        <property type="entry name" value="Glyco_hydro_67C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_67C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="13256" checksum="F416F224FC975D41" modified="2014-02-19" version="1">MAERFADVETCPEEFLLFFHHVPWEHELADGTTVVQRLYDNCFAGVEEARRLRDLWESLDGQIDERRFRHVAERFDEQVAQAARWRDVLTAYFYDHAGIPDERGRVPGDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ0</accession>
    <name>V6DQZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4657" checksum="549BEB99BADBC744" modified="2014-02-19" version="1">MFVVSNVVPSYIEKQGVEFLTDVEFIEMLEGELEVYTPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ1</accession>
    <name>V6DQZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_01317</name>
        <name evidence="1" type="ORF">BN903_282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076377.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81883at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014518">
        <property type="entry name" value="UCP022079"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09920">
        <property type="entry name" value="DUF2150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022079">
        <property type="entry name" value="UCP022079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="193" mass="21491" checksum="ADD013528F8D2BAC" modified="2014-02-19" version="1">MTDDDAVETFYTDERWQNWLDRLAEEELDPENEDSARLLLNLQDDAAIAVVKVLAAFDDDRIDEERAVEEVRDIRDIVLADVEFDDEDKVMLIDGVQTSLVPVFYAAEEYVVGGVVEGDVSEFVRAAAEAEEGDDLDAALGYVVQAGTRVIDGEALDIELVEDLEYGLVSEWVNGLDSLQSAIEDPEVVEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ5</accession>
    <name>V6DQZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4318" checksum="8744555FC371ED12" modified="2014-02-19" version="1">MTLDRACQSGSSVRPRYLKWAISPVYRLSNSEEFKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ6</accession>
    <name>V6DQZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_00374</name>
        <name evidence="2" type="ORF">BN903_287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076381.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117536at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10466" checksum="0A03B74009F2FB4F" modified="2014-02-19" version="1">MTLDTPTTDPAVVVAASERKRVVAGLADGTVETVADLRVRGRADEIAAELRETHLPALEEAGYIEWDREAGTIKPGPNFEEAAEHVDDLPMPEPSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ7</accession>
    <name>V6DQZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C444_18337</name>
        <name evidence="2" type="ORF">BN903_195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334865.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66764at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="23745" checksum="D5105CF9401994CB" modified="2014-02-19" version="1">MASRGSEFETSPAEGTEEDRLVRYGTSMFGGRPTFTLVRRETDSGGEWTLHELLPREQAEARRDRLERDGRSLSTTPVEDLISDVAGDDLLSKLDGWTWNGWVGAKVARLDPTRVRALQDVVREAIEDTPGETSEVLTGGAGFVFLPETAGVRLAVAFRGVKPLQRIDRMRSLARGVARMSDEECYYWYAKCRSPSSPNGEKALRVLLTDHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ8</accession>
    <name>V6DQZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6238" checksum="1E2F820D4C4AB21D" modified="2014-02-19" version="1">MVRVVDGYECVLHGCLHEPVPYKTRLSKGNRPEMGQTRPVIYRTVPARRTRSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQZ9</accession>
    <name>V6DQZ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08140</name>
        <name evidence="2" type="ORF">BN903_292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7083" checksum="C2B70263F5391B61" modified="2014-02-19" version="1">MAKWFRYGATHEEVIDFAAAHDADLIVVGSARRTGLDRLIHPNPLPGRLQRGADAPVLVVGPDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR90</accession>
    <name>V6DR90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="13243" checksum="1C12E6730895FBAA" modified="2014-02-19" version="1">MTEPINPENLREAYDQTTIPKPGTPERRPHTESDDETEIAVNVGDVIERRNPHNGGTVADVRYVLEVYDHGLVMWVLEDKRYTYCPSEFLREDLSEYDLRVHEDPWGLREDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR92</accession>
    <name>V6DR92_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidophosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purF</name>
        <name evidence="8" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="374" mass="40587" checksum="CECC7DEA84C07269" modified="2014-02-19" version="1">MREELAAAGHAFTSDGDTEVIAHDLARNLLEEDLVRAVKHTMNRIHGSYSLAITHDDTVLGVRDPLGNRPLCLGKIDGGYVLASESAAIDTLDGELIRDVRPGELVVLDPDGTGYDTYQLVERDATAHCFFEHVYFARPDSVIDESLVYEVRRNLGRKLWEESGVESDVVMPVPDSGRAFASGYADAAGETTPDGEPRESDDDGVEFAEGLMKNRYVGRTFIMPTQDERERAVRLKLNPIRSTVEGKSVTVIDDSIVRGTTSTQLVELVREAGAEEVHLRIGAPPILAPCYFGIDMATRDELIAADASTEEIREEVGADSLSYLSVDAVAEALGESRADLCLGCVTGEYPFDVEGEATDRDVDAPTPDAPPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR93</accession>
    <name>V6DR93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_00612</name>
        <name evidence="1" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008508">
        <property type="entry name" value="DUF790"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39640">
        <property type="entry name" value="PTHR39640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05626">
        <property type="entry name" value="DUF790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="198" mass="21360" checksum="76A54B632C91CC22" modified="2014-02-19" version="1">MIPDFAFDYDHADFRLFFEVMGFWTPEYVEKKLGQLADVEDVDLLVAVDESLGVGEEIAARDHRVVTYSGTVRVKDVVDVLREYEAEFVADAAAALPDALSPDADAIGLAELAAERGVGVEAIEGVSFPDHERVGRTLVRPAVLEALTDEIEPGMSLSAAEAALDEYGIDDASAALSRLGFRVEWEGLGGGTVREKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR95</accession>
    <name>V6DR95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
            <ecNumber evidence="2">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01794</name>
        <name evidence="2" type="ORF">BN903_351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="3"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="190" mass="20195" checksum="34D2F223105C1114" modified="2014-02-19" version="1">MLHTRAEIEAGEKVLVLGASGGVGHAAVQIADHAGCEVFATASTEEKLSHAEDCGADHVIDYETNDFADEIGERTGKRGVDVVVDHIGEATYPDSLKSMAKGGRLVTCGATTGGNPGAGLNRIFWNQLSVLGSTMATPGEVDDVLELVWDGTFEPRVREVLPMSEASRAHEMIENREGFGKVVVKPDSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR96</accession>
    <name>V6DR96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12101</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="66" mass="7336" checksum="EFF8CBDB8FBDAEBB" modified="2014-02-19" version="1">MKLGKLLSTPESIVGAFLLLATLWGTSFVAIEAGLHYFPPLLFAGVRYVXXXXXXXWSCEKDRERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR98</accession>
    <name>V6DR98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075953.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="15265" checksum="D1028C4D1034793A" modified="2014-02-19" version="1">MDSDNTSASNTDTDLYFEDAQTLHDEYRDQRATIRRKQAALEDLCGRLAHIDCDIGTASLGIDNDGTISVVISTPRFPDEVKSILHDFQWPRKFDNGYDTMSRCLTWSLKTDIDTLIEDHERNQQAHASATEQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA1</accession>
    <name>V6DVA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_14141</name>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077605.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31291at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="333" mass="37246" checksum="6A7833E98F378C21" modified="2014-02-19" version="1">MGKHERGWVEATEKLTARLANGAEPDDDLTEAGRPDLAEALADRLRSDFPDRTTMRHAGNSYDSLGDLVVGSADGETFVEAKFVASGGTRANLGQDTLTDFGLFVDATAWSDFREEIGFPEDREALLREFDDYPDDVRDWSYKSAVYDRAKHLKNAIDVSRGQNTGSRADEVLADPNASETEREAARIVNGILELDREEKLAYFDHLRAAEQDPRAIETFAHLIVCGYHTADALREHFDADLDEIKRLIETDAYRLYEVNKNTGSVAVENPVDLLAGFEWEDTRVEIPEDGTSVSVVTGPPDDRRRVLNIAYNWKNKFQGIQTPSMNVFVPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA2</accession>
    <name>V6DVA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease self-immunity family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Clole_0268</name>
        <name evidence="2" type="ORF">BN903_141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="212" mass="22003" checksum="FCEE67F951147C28" modified="2014-02-19" version="1">MVAPFFLTTIVLTVVFTATGGQSPVPRFATGIYSLVSILIVALLLQQLSPTTTAEILPTHVPGRREIGVTVIAILVTILIFDPVATFVVGVISGGGGTTDSFNSSIGAAIFIFSSVVIAPVVEEYLFRGVALDALRSRYGVGIAIVGSSVLFGGIHILIGGVSGLVSATLSGFVYAGMRIKFENLTGTIIAHSANNLYWVLTIAGVIPKIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA3</accession>
    <name>V6DVA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_11764</name>
        <name evidence="3" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11511" checksum="A980CB0DE8299776" modified="2014-02-19" version="1">MGEWAGVPFKPGESGASRRRDGGRARADTLIRCGRRTRDMVVSAGSVALVSITMTVLMIAAMLYLVWETLDSDIHSPSPDDSDAPELDAGDESGDAEEPQGELTEGSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA4</accession>
    <name>V6DVA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
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            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4746" checksum="7867C5D21570EBC6" modified="2014-02-19" version="1">MPNQEQSVSLISVAKRRLHAMRGECLVLGRIEPRELEVKCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA5</accession>
    <name>V6DVA5_9EURY</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="primary">C437_14874</name>
        <name evidence="2" type="ORF">BN903_146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
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            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076883.1">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="191" mass="21373" checksum="FE43EF4B430074C5" modified="2014-02-19" version="1">MSTRSQLRFVQRVEQPDESESDDERIAQVYRHSDGYPQTVLQDLAELKELLDATRTERGPAYTAATFVFLDKLSTVDLYLDGSPERTIDAAQPADLLDPANMEHLDQPLFLLGHGIEDPAGGIHGDEEYLYVVELPTTNAFDEPAEWTVKVSGHSAFPRWDGPTDEAFEQARWQFHGSLDDALTELVAKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA6</accession>
    <name>V6DVA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
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                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8489" checksum="06D7EE5E8A2B1F66" modified="2014-02-19" version="1">MLQTSSSISEGLYRELPTCVATLYRWYSIVWIRVSIIGLYREQFTLQFKCFNPQQRFGTDGLLIALNFMNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA7</accession>
    <name>V6DVA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="1" type="ORF">BN903_151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7266" checksum="10043BB78531F160" modified="2014-02-19" version="1">MYQNIEVGSRAVLYRAPDSYRYKWRGGILIGEKSADGINVQRWFDCPDGGRKLHSTQSTTLSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA8</accession>
    <name>V6DVA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_2886</name>
        <name evidence="1" type="ORF">BN903_156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076890.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125005at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="7138" checksum="35C7D46AD1BEE468" modified="2014-02-19" version="1">MDQHVKQGYRMHCALSNLNRLDVDRLDDADQERIERARTLLKEVSLLTQPADGDGRDTRVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVA9</accession>
    <name>V6DVA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5534" checksum="F808B15BA2CEA0A8" modified="2014-02-19" version="1">MGRYLTPPLLIALCLEGRHFWRERRRDYRVVVRGIVQKTIPQVNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB0</accession>
    <name>V6DVB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="10273" checksum="163989D36AB4923C" modified="2014-02-19" version="1">MFPPHSFRGFRAEVQSLNNTLISRSRCIFHWLSLHRRPAVRCSNHRAFSERPHPEGQLPSRLFLRGKYIYSFLCGKLLYLYGCYQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB8</accession>
    <name>V6DVB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C454_18054</name>
        <name evidence="1" type="ORF">BN903_166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10225" checksum="E25A53AF6C09EE14" modified="2014-02-19" version="1">MTAYTWGKVERVSHPICIDCAIQATPDPEERNHYACDSCGLVVDAFAALTRFRVELGHLEGPVHLCARCSPGGLATYWTRDLEQHLVRTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB9</accession>
    <name>V6DVB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08575</name>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077622.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101942at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="18841" checksum="71B3467463EC00C3" modified="2014-02-19" version="1">MADSYRGVFGAIPYAFRATESWTMRAYAALGALTAGFVALVVTLGLVVWMGETVSAQGGTFLFSRSLFVVAGLAAVGPLLAPILFVARRHRRDDPVAADYDRWMGVVGFLFLVSLYLAMVISAPADLRDPSGSAVINALYALPPLAGFVPPTAAALAVFATHFRLRGGSDAGATPETDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC0</accession>
    <name>V6DVC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Halar_0039</name>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077128.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57042at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="538" mass="62127" checksum="F83E283B47A59194" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC1</accession>
    <name>V6DVC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription regulator sirR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C472_14191</name>
        <name evidence="9" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077624.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110491at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="234" mass="25302" checksum="9DED533D336ED476" modified="2014-02-19" version="1">MPTDAVEDYLKAIHRIESRSGPPVSTSQIAEALDKTPATVTSMVETLADRGLLSREKYTGVELTPAGEVAALEVVRRHRLIEAFLAEQLDYEPTEVHDEADALEHHVSEEFTRRVERLLDYPAADPHGDPIPPADLSTPEDAGTTLVAALEPDERGTVVRVSDRDPDVLEFLVDAGITPGTTVEVVEVTSFGLVTVRTDDGDEHGLPEAVADRVYVRRAADSAAATDRQEAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC2</accession>
    <name>V6DVC2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S8e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rps8e</name>
        <name evidence="6" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077627.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116294at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00029">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020919">
        <property type="entry name" value="Ribosomal_protein_S8e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_S8e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_S8e/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="PTHR10394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="123" mass="13336" checksum="62319B1FC1AD1C5D" modified="2014-02-19" version="1">MKDQGRSTRKRTGGRLKHASNKKRHQLGREPAETTVGETRLQYIDARGTDKKVRALSTNVAQVADGGEVSEAEIENVVDNPANVNYARRNIVTKGAVIETSAGRARVTSRPGQTGQVNAVLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC3</accession>
    <name>V6DVC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_15024</name>
        <name evidence="2" type="ORF">BN903_171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076902.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79034at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="337" mass="37975" checksum="0A201D75A4A523C5" modified="2014-02-19" version="1">MSSATDPTKRIPKSLGTDTQFLGKYSLTDLAVAGLPGVLVVLVTQVAIPPSLTVRGIPVSALTIPVAAIAIAFGGLFVYLTPSYTNSLDWLGTFVGFHRSETEIAHEEAKEYTHVERVYPRHDAIERTDRALVGAIQVSPPTMALATDEEWEQKTEAFQDFVNTTVEFPIQIYSTTQSFPADEYVGRYEDRLSDPDVKSNEKLQALIEHYVDWYDRELAQRQMTIRDHYVLIPVRPEEVRYERASLLEKLAGIPVLGILVQIVTAPPEEEERAAMLEELDERRRRVERGLRGIEGCDTRPVDSDELTRLIAEYWIGKEIEYGNPEQVLRTSPVITNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC4</accession>
    <name>V6DVC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_05016</name>
        <name evidence="2" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077630.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55424at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017271">
        <property type="entry name" value="Tscrpt_reg_HTH_MJ1545_prd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037724">
        <property type="entry name" value="TF_HTH_MJ1545_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="233" mass="25619" checksum="199E9018C3F8D931" modified="2014-02-19" version="1">MSDAREELSRRIAGEITLSDDPGATLRKWRTDFDVSQTELADQLGVSSSVVSDYESGRRESPGIGVVRRTVEGLLDIDERRGGGRLRQHARVLSAGFESDIVHDLREYSTAVPLAEFYEAMGATEIVRGDHDHVNGHTVIDSIQAITRLSSEEFYRLYGQSTNRALVFTRVTRGESPLVALRVVSPTPNAVVLHGIEDGNLWDHAADLARVDGFSLATSNRDLDDCLADLQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC5</accession>
    <name>V6DVC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_14216</name>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077628.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103666at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14975" checksum="BDAD021687045D58" modified="2014-02-19" version="1">MVRDPSRDPEPPSVDEVLDALADDAARRIVAALTEPKTASELSEECDIPLSTTYRKLEKLTDASLLSESTDIRRDGQHTTRYSVSFDAVTVSVDDGAENTEDRREFDVEFSRPERTRDERLADLWSELREET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC6</accession>
    <name>V6DVC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor TFIID (Or TATA-binding protein, TBP) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C444_08780</name>
        <name evidence="4" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="PTHR10126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="194" mass="21340" checksum="E4D4DB5BF95D0885" modified="2014-02-19" version="1">MIMCDYPNQDSIKIVNIVTSGGIDREINLEKVANDIKIFDVNYDPSNFPGVVIKTAENGSTILLFRSGKFTVTGSSTQDEVKESIDVFSESLLDLGIINSAINRDQYDIVNLVCSAEVEIDEDLNSIAIILGIENVEYEPEISPFIIYRPPNHNCVMTIAGSGRIVVTGMTSLDTAKEAVIHLEKILNQARENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC7</accession>
    <name>V6DVC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_15049</name>
        <name evidence="2" type="ORF">BN903_176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6149" checksum="B0AA7F40A38EA93B" modified="2014-02-19" version="1">MADTNTTSNTGGTSAETSDDVARINMRIPQEKYEWLQQELDSFTSDTARFQYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC8</accession>
    <name>V6DVC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08670</name>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077634.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115092at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="265" mass="30643" checksum="2DC66A07237D6B41" modified="2014-02-19" version="1">MISDAQLRRLARDLNVRLGYAEKNYVNSWILWAIYTSPYGDNLLFKGGTALSKLYFPETWRYSEDLDFGVRGNYGGSEAELQGALEDAARASGIDFEVTKHRKLQKEAYPTHYVDINIQYNAVLGHKNTTSLDVMIDEYVAFTSLDHRHSYEDVPEFELTAYSLEEIFAEKLRALYQRSQARDYYDLYRMITEADIDDSVIFPSISRKCEHDGLDIDLRDGLPREKRDEIRDGWQNTLPDLVADLPDFDPVYETLEEYVASLADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVC9</accession>
    <name>V6DVC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vng6047h</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">VNG_6047H</name>
        <name evidence="1" type="ORF">BN903_181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7482" checksum="BB384C60CB355863" modified="2014-02-19" version="1">MTVYIEAGESYDGMSDLIVKAAVKNALSENNVSADFYDALNEEVAELLDDAAERAESNDRKTVQPRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD0</accession>
    <name>V6DVD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08660</name>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8636" checksum="520A89A0E85AE3DF" modified="2014-02-19" version="1">MLPSGIFWWVIPVSIVSAVMTVDASRYWSFSYLAGVCIGIYLAIPIFLEAGLLSTLDILIYGGLTLAAVGLRIKIHSSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD1</accession>
    <name>V6DVD1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">C464_05945</name>
        <name evidence="13" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="12">
        <location>
            <begin position="63"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CDK40142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="320" mass="35732" checksum="2EA9A4FBF33108C0" modified="2014-02-19" version="1">MSDSDGATADDDVEVGGDEEVSDLPADLDAVRDALVDWYEADHRAFPWRGTEDPYEILVSEVMSQQTQLDRVVPAWEDFLDEWPTSADLAAADRADVVAFWSDHSLGYNNRAKYLHEAAEQVETEYGGAFPETPDELRELMGVGPYTANAVASFAFNDGDAVVDTNVKRVLYRAFDVPDDDDAFERVASRLMPAGESRVWNNAVMELGGVACGKKPRCDEPGCPWREWCHAYQTGDFTAPDVPEQPSFEGSRRQFRGRIVRLLGEHDEMGLDTLGHRIRVDYAPDGEHGREWLRSLLSDLSDDGLVQIEEGNDQITARLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD2</accession>
    <name>V6DVD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C449_12163</name>
        <name evidence="2" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334944.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99792at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="16754" checksum="1845A4D2E54F59BB" modified="2014-02-19" version="1">MGESKQVTVYVPKEMVVGWDEERAELNMSRSEYVQSMVCAGRKKFSLDHEVDETKRELRRERNELKNKLESARDDINDLEVRAYGGEREALIEVIEREPGITYADLVRELGNDLPARVSQHLDDIVGEQIERENNCFYPTDFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD3</accession>
    <name>V6DVD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6329" checksum="6F169CAE55DEA33D" modified="2014-02-19" version="1">MRQNSDFVEISNGALCRTQTDRRVTRLLARASNLIYPSVALLKSHSSDTFSSETAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD4</accession>
    <name>V6DVD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5665" checksum="F6A20E4755A5F676" modified="2014-02-19" version="1">MLKRLRPQISVRVIYGAFRKLNPLTAVLLFPTGVSSLVRSGQLSLLVISAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD5</accession>
    <name>V6DVD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11398" checksum="DBE467B2F30A9404" modified="2014-02-19" version="1">MIGQPRGHLRPGVRRVEVGEQEFRKATPPRPPLRFSEVGRDRERLGVARLARPRQRRSCEPXXXXXXXVAGCGFAYGSGRTLRLEGSWSVVIVGSGSPARGVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD6</accession>
    <name>V6DVD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_14306</name>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077637.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93701at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="30439" checksum="97160DD749A4E5DA" modified="2014-02-19" version="1">MARLPFGVARLDSILGGGAPPGSVVLLAGEAGAGAREFAYTSAAMNALARADEELFDLYYGDIDAGAALPESVHYISFTADTDAITREMGYTMADEIVDAAVDEIEFRDLSPEYFQLSPVPRDWYETATASITELGDRGEYEDVLTAFGDYLSEHGQGSLVCIDSVTDLVSMVSDDTDWSDVAMVMKGLKKAAYEWDALVLVLVNTEALRDREFGTLMDAAGGTLQFSWESGGSQRARTMFVREFRGVLSRLEDENIVRFETEIHEGGFDISDVRKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD7</accession>
    <name>V6DVD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14346</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077639.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111301at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="16633" checksum="EB13935209516770" modified="2014-02-19" version="1">MYRNGHIGASLAVYAPFGFLVTALVSLEAGLLGALGVASTAMVPDLDVRVPFVKHRGITHTVWFALLVGAAFGTVGLALGVRNDAATALLFGGVGFLFGAGTIVSHLLADALTPMGVRPYAPVRDDEYTLDLFAAANPVANYALLGLGGVTAAVALVAGEAVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD8</accession>
    <name>V6DVD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4792" checksum="D986A9FF755863D3" modified="2014-02-19" version="1">MLGTARSGKSRHFGRFNVLLLYRSVLTDPLRSVDNRKTLISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVD9</accession>
    <name>V6DVD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8772" checksum="579FEB17004889CF" modified="2014-02-19" version="1">MSGCDSTREPPARESIAGAKRWRLTRLGRREVLCWAVRGGTRRGSREAGAGDARTAGTSSASDEDRSERAPASRLGLQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE1</accession>
    <name>V6DVE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C472_14356</name>
        <name evidence="9" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006686">
        <property type="entry name" value="MscS_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01246">
        <property type="entry name" value="UPF0003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="411" mass="43921" checksum="C3723D5B4DF56350" modified="2014-02-19" version="1">MIGGLGTRFGAVLSDVATTEGRIAVTAGIALVTLAIGWLLLPRAVRAGERTVSGWVEQFLDNRAGKSTEGAVETLREGVPTSFLLRLAVGFLQLALFALAGVAVLTLWGRFDLVVAVRPVAEDGVRIGAQVLVSAVLLGGVYVASDALEAYVADLSAGSDRITAHQEQLLTRLAQVGLLVLALITVLGIWGVNLGGLLVGAGFLGIVLGMAARQTLGSLIAGFVLMFARPFEIGDWVEIGSEEGFVTDITIMNTHMRNFDGEYVVVPNDLVANQAITNRSREGRLRIHMEVGIGYDDDPDEAAAIAEEVLNGIDHIANNPQPYAIPSGFGDSAILLDLRFWIDPPTPQARWRSKAIAVERIQDRFVDAGISIPYPQRTVSYPPDTAEAADTVERVERTDEDGDGRSDNRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE2</accession>
    <name>V6DVE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5558" checksum="60192F95AA911741" modified="2014-02-19" version="1">MPFAVAGGDRSRARATAQSVGFAPISGWDATQRWAVERTASYGPTDRNGRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE3</accession>
    <name>V6DVE3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit Rpo5</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rpoH</name>
        <name evidence="2" type="synonym">rpo5</name>
        <name evidence="4" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077145.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123463at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="SSF55287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb5_C" evidence="3">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8549" checksum="AAC977E3381DAC28" modified="2014-02-19" version="1">MVDVSQHELVPDHVLLDDPEEVESVLAEYDVKKTHLPKIKRTDPAIPDEAEVGDVVKIVRNSRTTDEAVVYRLVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE4</accession>
    <name>V6DVE4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="3">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">pdxS</name>
        <name evidence="7" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077643.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64452at2157"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="SOR_SNZ" evidence="6">
        <location>
            <begin position="16"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribose 5-phosphate binding" evidence="3">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="302" mass="32897" checksum="0B997C8782FFC326" modified="2014-02-19" version="1">MPEATDLEELKRGTELVKRGFAQMQKGGVIMDVVNREQARIAEDAGAVAVMVLEHVPADIRKRGGVARMPDPERVPEIIDEVSIPVMGKSRIGHRKEAEILEALGVDMIDESEVLTPADDEYHTDKRDFTSPFVCGARNLPEALRRVHEGAAMIRTKGEAGTGDVNQAVKHQRTIKNQIRTLTGLNYEEREKWAREHGAPRDLVHETAEAERLPVVNFAAGGIATPADAALMMYHGCDGIFVGSGIFGAEDPAAMGNAIVEAVNNWDDPEELARIASGTGKGMKGQSNEDMKEEEQLQGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE5</accession>
    <name>V6DVE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6168" checksum="E1A82698BEF3E54B" modified="2014-02-19" version="1">MRLVRCRCCRSHRYSIGVCRFRISPPQSGHEPGLSSARMMFPHSKHSYGDSSSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE6</accession>
    <name>V6DVE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="341" mass="37445" checksum="762BD2CD145E383F" modified="2014-02-19" version="1">MKRRDLIAVGSLSLIAAGSGCMDLSEGESQDEPRVSMPVTVDNIRVGFDTEQVIEIFDLAGSQLPEENQEHTVRIDVTPLEQYGVNTEDLSVETTQGRYGSTEAYNNNVDTLDITDGIIDLVIRTSEDASDADPIALKLTGYQFTDVEAVTEVQYDVQSPDDHVEFRQGSFHGGKSGSKCGFALSLDGEFTLVNPQLLPPTLCPNSINTYRETQQDLYVEWLTPEADEVVIEIDISLLEEYGTIEGFTIEPLSKSRNSDEPMVWGATLENLAIDDWTISMKLVPDSGTNYASVGVQLSGINLNIGDPLRDVSYDMTIEGDADETVETESFDIVDDPPDNDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE7</accession>
    <name>V6DVE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_10873</name>
        <name evidence="2" type="ORF">BN903_201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076923.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102573at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14554" checksum="0FBB86A9C77C7326" modified="2014-02-19" version="1">MQARHIDHINLRIPTDGAADAREFYVEKLGFDIEDALYAADDKPFFDVRLSETAVIHLWPTESFEAPTKTNYNHVAVIVEESVDKIKTELADVGVEVEKTLDSPLGATGKAGAVYVRDPFGYRVELKSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE8</accession>
    <name>V6DVE8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable transcription termination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_05819</name>
        <name evidence="5" type="synonym">nusA</name>
        <name evidence="7" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Participates in transcription termination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077150.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99842at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_A">
        <property type="entry name" value="NusA_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010212">
        <property type="entry name" value="NusA_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01952">
        <property type="entry name" value="nusA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="KH type-2" evidence="6">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="14750" checksum="9A23E4E77A1A1E5A" modified="2014-02-19" version="1">MRELSDEARRYIGRFDELTGVTPTDCLVEGDRLVFVVPAGEMAAAIGQGGETVAEAERRLAKSIELVEDADTAEAFVASTLAPAAVNAVTISEQTDRVAYVEVPEADRGVAIGADGANIETARRLAERHYDVDDVQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVE9</accession>
    <name>V6DVE9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Proteasome subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">20S proteasome alpha subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Proteasome core protein PsmA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 7" type="primary">psmA</name>
        <name evidence="7" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00289_A">
        <property type="entry name" value="Proteasome_A_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019982">
        <property type="entry name" value="Proteasome_asu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03633">
        <property type="entry name" value="arc_protsome_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PROTEASOME_ALPHA_1" evidence="6">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="272" mass="28864" checksum="BE089670EB6ADFE0" modified="2014-02-19" version="1">MMGGNDQQAYDRGTSLFSPDGRIYQVEYAREAVSRGAPSVGVRTTDGVVFVAMSRPSSSLMEAESIEKLHKLDDHLGTASAGHVADARQLIDLARRQSQGNRLRYGEPVGVETLTKFVTDHIQENTQRGGTRPYGAALLIGGIDDGEPRLFAADPSGTPNEWKATVIGGGRQDIQGHLEDEWRDDLSLEDGIELAVAALAAHDDDFEPSDLAVATVTEADGFRTVPVDEVEAAFEAAGLGADEADDEGTEADAESDADAGDADEEDADGSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF1</accession>
    <name>V6DVF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_09124</name>
        <name evidence="1" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023906">
        <property type="entry name" value="rSAM_target_put"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03995">
        <property type="entry name" value="target_X_rSAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="14668" checksum="A37BA7F8E2DFD73B" modified="2014-02-19" version="1">MDRSTGRAVVTLPSNMFARSGIRVGNVPPIEMATHDDHDHDHGADPVTDHVHENSWSANLEGPEHAANRDLLVRQAIEAVEHTAAGNHVNLVTHGDHGHPEAYLFDALEAAFDDDLDPEYVEQCGCGGHVVRVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF2</accession>
    <name>V6DVF2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-carnitine dehydratase/bile acid-inducible protein F</fullName>
            <ecNumber evidence="1">2.8.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_13770</name>
        <name evidence="1" type="ORF">BN903_206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.16" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033608">
        <property type="term" value="F:formyl-CoA transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="365" mass="40255" checksum="287D78A453FF3A03" modified="2014-02-19" version="1">MIKVEHPSTGDHLRHFGPQKEGVGLWWKYLGRNKQSVTLDISTEEGKVVFEDLVADADALIENFRPGTLERWDLGYDHLSDLNPGLVMLRLSGFGQTGPYSDRPGFGTLAEAMSGFAYLNGYPDREPLLPPTGLADGIAAMFSTMAVAFALYSRDANGGSGQYIDTSLIEPIFSLIGPQPLRYQQLDEIEERSGNRSTSSAPRNVYQTGDGRAVAISASAQPIAMRVFDAIERPDLKDDPRFADNEKRLENVEELDAAIQDWMDDHTREEVIDRFEEYEATIAPIYNVADILEDEHYQARDAVVDIPDDQLGTGAVQNTIPHLSETPGSISHLGPPLGAHNEAVYGERLSYDEETLAELDAEGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF3</accession>
    <name>V6DVF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <ecNumber evidence="3">3.6.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08059</name>
        <name evidence="3" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077154.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="94658at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="17022" checksum="EEA822D27937917F" modified="2014-02-19" version="1">MFDSGAAVAAALSAAGADLDDAQRQPNGVDLTVDAVFEPTEPGFVGRDGKRVAERRELEPEDGRYRLDRGTYVVRYGEPVRIPEERIGFVLPRSTLLRNACTLDTAVWDAGYEGVGEGRLDVGHAIEIEPGARIAQLVFAEADHDGTYDGAYQGERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF4</accession>
    <name>V6DVF4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methionine aminopeptidase</fullName>
            <ecNumber evidence="3">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">map</name>
        <name evidence="5" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="13"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="275" mass="29615" checksum="778E6E87D57140D7" modified="2014-02-19" version="1">MSHGSLDADAVESYREAGAVLTEAMNEAREMVEPGRTHLEVAEWTEDFVREQGAGLAFPVNVSVDPEASHATPGRDDETEFGEEMVCLDVGVHVDGYIADAAVTVDHSGNPELVEAAEMALEAALDEAGPGVEVGVVGQAIEDVIRGYGYTPVLNLSGHGVQRYDAHTGPTVPNRGVDRSVELEPGQAVAIEPFATDGRGKVGEGTDEEIFEQQGSASVRDRRARQALEEIEAFDDLPFAARWLESDRAEMSLRRLKQANAIKGYPVLRRTTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF5</accession>
    <name>V6DVF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6516" checksum="D1D8F4FB6B1D044B" modified="2014-02-19" version="1">MRVRCRTLGPRRAERESGAPPEADAPRRAAARPNPGVFKAGESTPIYHTPAGHGEPTSARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF7</accession>
    <name>V6DVF7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C494_15728</name>
        <name evidence="4" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="381" mass="43835" checksum="FD1AC47D410C453C" modified="2014-02-19" version="1">MSTNVSRKLYKKKKEIYGKIYQTIQHPLKSVVHQKLIRQSKLKQVASKESIIRFGKREQYQPDLGRHEWIVKHCGTRGPQTFPRPFTCVIDDAKLVGSYPIPLTNSHRCPLDAIGTEDTFNLNLLFSLKSIPGEARSYLSKNSFDVDLGFLMYDYWSSGYFHWHFDNLIQLRGLEAFESTTGRRPKLIVPPDLSDWQQESLEIMGYDEDDLVRWEPPLGTVEELVVVTNQRPRPDSVRWLRQSLDITNVDQPSNSRIYVSRSDADRRRVLNEEEVMACLSQYGFDKFVPGNHTVRDQIRTMKNAEVVVGPHGAGLTNILHCPEDTNILELLPKSDPRRHFFDLANKLNLNYSCCLCDDSGTDLVVDVEALHQELQEVLDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF8</accession>
    <name>V6DVF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen</fullName>
            <ecNumber evidence="2">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02789</name>
        <name evidence="2" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077650.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98508at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="16684" checksum="1064696A1ADA5F57" modified="2014-02-19" version="1">MLDPGDSAPEITLTDHRGETVTVDPAAASHTVVYFYPRADTPGCTAEACSFRDEWDAFEDRDVAVVGISDDPVEDLEPFAAEYDLPFTLLSDPDGAVAAAYDSYGEKSMFGNTFDGVFRNTYVLDGTGTVALAYEGVSPEDHAVEILDDIDALDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVF9</accession>
    <name>V6DVF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TrkA-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C461_08329</name>
        <name evidence="3" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077656.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="59289at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="2">
        <location>
            <begin position="242"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="402" mass="42211" checksum="5B5271C4EF71792D" modified="2014-02-19" version="1">MELTRDWVTVRASIALTFAVAILSILAGLAQIGGLGVSGPLAPYVPDVVRQTVGFTGTITGFTMLASGFALRNGYRVGWYSTAVLLPLTAIQGLMQASVLSFPLVALSLLSMPALLYNRGRFDRQFRPSPTQLAAGAALVTAISYGTVGSYALRDQFNGVETIVDAFYFTVVTASTVGYGDVIPATGPDSDIAQLFVLSSLVMNVAAFAVALGVLLTPAIEAQLSKALGKMTEKQIDLLDDHVLILGYGDLTEPILEELDGRGGTTYAVITTNEAAARRLDERSVPTLTADPSDVEPLERAHIADARAVVVATENDAQDALAILTARQLNPGVRIVAAATQRENVNKLRRAGADQVISPSTLGGHILIDCAFGSNSDEATTDLLGGALDGDADRDAMTRDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG0</accession>
    <name>V6DVG0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glyS</name>
        <name evidence="9" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076965.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32623at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="4"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="587" mass="64405" checksum="75544DDD3831DFBF" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG1</accession>
    <name>V6DVG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyhypusine synthase</fullName>
            <ecNumber evidence="2">2.5.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_09184</name>
        <name evidence="2" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="33806" checksum="6B2A52D86AC7F927" modified="2014-02-19" version="1">MTVSELVDGYGDAGIGAAAVNEAGDVLAEMFANEDCTVFLSLAGAMVPAGMRRIVADLIRDGYVDALVTTGANLTHDAIEAIGGKHHHGRTHDPEKSLREHDEGLRDEGVDRIYNVYLPQEHFAEFEGHLREEVFPALEADPDADGTDAVSIADLTRELGRANAAVNERDDVPEGPGVAAAAYECDVPIYCPAVQDSVLGLQAWMYAQTADFTLDALADMTELTDLAFDADDAGCLLVGGGVPKNFTLQTMLVTPRAYDYAVQITMDPEATGGLSGATLEEARSWGKLEKDARNASVYGDATVMLPMLIAAARDRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG2</accession>
    <name>V6DVG2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05749</name>
        <name evidence="2" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077160.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="137148at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="163" mass="17338" checksum="5126E568C577066D" modified="2014-02-19" version="1">MSDRASNAESRTRSAERRRRPTRRAVLVGSALTAGGLSGCLGGAFRDESPTAAVSARSTEPVDDPEHDASVEVDDETARIDGRFAAPVECVALDVNTFTSSPEEGIAIVEVAVTETRNGCKGPAAVEYEGEVAFGFPLRDLTVNHRLDGGEDRVTVARYEQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG3</accession>
    <name>V6DVG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="260" mass="27829" checksum="3ACE7F67CB76B018" modified="2014-02-19" version="1">MPHVEVDVLVLDAAALVDLGQLGAGDDVAGGELAVVVRVAVFEHEPLAVLVVEDSALAADALGDEDAGRRQRRRVELDELHVLHRDAGAVRHRDAVAGVGDRIGGVIEHLPHPARREDDAVLRAEAANLTALDVVADDAVTGPLGGVVLVGDREIHHVPLVVHRNSAFDHLLVHRVEHLVARLRAGVRRPREGEPAERALGDAAVVLAGERHPPVFEPDVPPRGSLYRGPRPPGRPRGSPSPSSCRTRGPARSRRRVTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVG4</accession>
    <name>V6DVG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6738" checksum="07A00CAF08EDBAA9" modified="2014-02-19" version="1">MFERLSDRGFDVGHGGSTSALGGEKTGSLTGQMSEFATSRGLSILSCPSDLTTLSWQRYLIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH6</accession>
    <name>V6DVH6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YrdC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_09813</name>
        <name evidence="2" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9093" checksum="15335BBDA8C6CDC9" modified="2014-02-19" version="1">MPDHDLARDLLAETGPLTATSANVSGTGSVTRLDDLSDRIRGGVAAVIDGGETPGTESTVVDPEAGEIHRRGAMAGAIEAWLADPPVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH7</accession>
    <name>V6DVH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02609</name>
        <name evidence="3" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077664.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="75455at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014470">
        <property type="entry name" value="UCP01500"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10028">
        <property type="entry name" value="DUF2270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015000">
        <property type="entry name" value="UCP01500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="235" mass="26399" checksum="1FD33B8D1AF99120" modified="2014-02-19" version="1">MPDPPEDFDPESREEREVAAEAASDRSDFLSLMGHTYRGELGRTSSWRTRIDRTTNWAVVVTASLLTWTFSNESRPHYVLLIGLVMLSVFLGIETRRYRTFDVWRSRVRLLEENVFANALDPEGVEQSNWRELLSEDLREPTIKMPGVEAVSRRLRRVYAPLFSVLIAAWVVRLTVFTPPGSGVVATAAVGAIPGAFVLALVACFYVVVLGLTLRRAPRQAKGEMGTAEDADEWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH8</accession>
    <name>V6DVH8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="9">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lpdA</name>
        <name evidence="13" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9" id="KW-0274">FAD</keyword>
    <keyword evidence="3 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="12">
        <location>
            <begin position="11"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="11">
        <location>
            <begin position="347"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CDK39565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="469" mass="48939" checksum="F3795DBBE9229AF7" modified="2014-02-19" version="1">MVVGDVTTGTEVLVIGAGPGGYVAAIRAAQEGLNTTLVEKDAYGGACLNRGCIPSKALITGSGLAHEAGNAEFMGVHADPAVDMGKMIEWKDGVVDRLTSGVEKLCKANGVNLIEGEASFVDEDTVRVAHGGDGQGSETLSFEHAIIATGSRPIQIPGFDFSEPHVWSSEEALDAEVVPDRLGIVGGGYIGMELATTYAKLGADVTVIEMLDDILDPYEDDVKRIVRKRAEELGVEFHFGEGASEWSEAPDGGYLLHTETEDGEESSYSVDNDXXXXXXXDVGNAGIETDDRGFIETDDRTRTAVEGVHAVGDVAGDPMLAHAASNEGIVAAEVIAGEPAALDRQAVPAAVFTDPEIGTVGMTEAEAEDDGFEPVVGEMPFNASGRAMTTGHTEGFVRIVADDETGFVLGAQIVGPEASELIAEVALAVEMGATLEDVAATVHTHPTLAEAVMEAAENARGQAIHTLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVH9</accession>
    <name>V6DVH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intracellular protease PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_13802</name>
        <name evidence="3" type="ORF">BN903_114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077667.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98884at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01382">
        <property type="entry name" value="PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="5"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="197" mass="21380" checksum="A50F210F6AB52DAF" modified="2014-02-19" version="1">MTGQQILMIVGDFGEDYEIMVPFQALQAVGHEVHAVCPDREGGESVKTAIHDFRGDQTYLETRGHNFELTHGFDEVDPAEYDALVVPGGRAPEYLRGYDEVLDAVRHFFEADKPVASICHGPQILAAAGVLNGYEMTAYPAVRPEVEAAGCSWVDGVTTDGNLVTGQAWPDHPEWIAQFLDLLGTEIEHGPAAATAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZI3</accession>
    <name>V6DZI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mut/nudix family protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_10898</name>
        <name evidence="3" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="76"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="23299" checksum="6ECC3C6DEE849E11" modified="2014-02-19" version="1">MSASRPERRRPSARRRAAGDVKKAVPVGGMSRIIISTGRVGGAYVDHPSDGSIRRVRDERGTSSVPPNVPEGVPERRELRVGAKAFVTDRDRVLLVKERREDGSTFWTLPGGGVESGESFAECLRRELDEEIRCRATVGERVGRCVYRHTSRPATTVYSVFDATLGSEPEPNPTERVLDHAWLEPADLLPTTLDPVERFIHQSVAGTDGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZI6</accession>
    <name>V6DZI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="7">2.1.1.182</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ksgA</name>
        <name evidence="7" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="6">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="15832" checksum="FC9F1BCAF96CBC6E" modified="2014-02-19" version="1">MLMFQAEFAERMVASAGESEYGRLSVSAQHYADVEIVERVPKEAFDPQPAVESAVVRCTPRDPEYTVGDEAFFLRFVKALFTQRRKTVRNAVRNTAHISGLDDPEAVVDAADEELLSSRPGTLEPAAFAALAELARERGSPTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZI8</accession>
    <name>V6DZI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoesterase RecJ domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_09861</name>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="36575" checksum="3C2E8AB64B9A552F" modified="2014-02-19" version="1">MEDVTRDLNFALEGRARHGQKLPFLLMLDNGSTEEDVPAYENLAHYDIPIAAVDHHHPDPEAVEPLLDAHVNPYLHDEDYRVTTGMMCVELARLIDPSITEELEHVPAVAGLSDRSKAEAMDDYVALAEDAGYDESDLLDIGEALDYAAHWLRYSEGKTLVNDALNVGCDDEERHEELVAFLSERAERDVERQLDAVDDHVEHERLASGAHLYRIDLDEYAHRFTYPAPGKTTGELHDAKVKETGDPVITIGYGPDFSVLRSDGVRLDIPNMVTELNEELPEAGVSGGGHLVVGSIKFVKGRRSEVIEALVAKMADAEIDEALSSTIALDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZJ1</accession>
    <name>V6DZJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_13532</name>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8329" checksum="F0509C13D339B8E0" modified="2014-02-19" version="1">MRIAAAGLGRPKSICPPLPDRVVMTTGDRIERDVESAADERPTVAATRCSQERTVFTEQGNTDAWIATDLTVDLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZJ3</accession>
    <name>V6DZJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c oxidase subunit I</fullName>
            <ecNumber evidence="8">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C468_03728</name>
        <name evidence="8" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.9.3.1" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01660">
        <property type="entry name" value="ba3-like_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033943">
        <property type="entry name" value="Ba3-like_Oxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="7">
        <location>
            <begin position="26"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="524" mass="57716" checksum="80A758F60AD7A924" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZK0</accession>
    <name>V6DZK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SirA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_2416</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078138.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124510at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8551" checksum="DFC82032D71E07D9" modified="2014-02-19" version="1">MSDIDIEPTDTVDARGAACPGPLMDLIGRVRSANSGDVIALLSDNDQSLTDVSEWVGETDNELLAVDESGDDYDFYVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZK3</accession>
    <name>V6DZK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CheW protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_13392</name>
        <name evidence="3" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="2">
        <location>
            <begin position="145"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="292" mass="32446" checksum="9538804400630A40" modified="2014-02-19" version="1">MRRQHQHRRRRLLHQPLDGFESAHTGHLDVHRHDVGAGLGDHRERLFSVPRLADDRDPRIAQEITYQTPHERGVVDDHHPRRPVPTAAPIRRPAHVPHRTQNQHKSTDPVITPDNSGDTIICRLTAGTGMAATEANTESTADAEPTKVLEFGLGDGTYCLDIGVIDEIVDAGELTRIPNSPDHVEGVMDLRGRTTTIVDPKTLFDIDEEGPRERIVVFDDSEIDEGGTVGWMVDEVFQVRDVAPEDVDQSTTVEEEGVRGIVKSDDRFVVWVSPDVDDELAAELDDVEAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZK4</accession>
    <name>V6DZK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4041" checksum="743037F2AE97E4C6" modified="2014-02-19" version="1">MLPIQTELANMTNAWARPEGSLNTTSLILEGTEQVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZK9</accession>
    <name>V6DZK9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Adenylate kinase</fullName>
            <shortName evidence="5">AK</shortName>
            <ecNumber evidence="5 7">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">adk</name>
        <name evidence="9" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="5 7"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078167.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55175at2157"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3 5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADK_lid" evidence="8">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="5">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="58"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="83"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="22706" checksum="6650BBE82923EA4F" modified="2014-02-19" version="1">MSHRILLLGAPGAGKGTQSAKLADEYGVEHVTTGDALRANKEMETEYGTPKSFMDAGELVPDPVVNEIVEAALADADGFVLDGYPRNLDQAEYLSSITDLDAVILLDVDEEVLVDRLTGRRVCDDCGANYHVEFQPPEEPGVCDECGGELIQREDDTEETARERLEVFYENTEPVVDHFRDEGVLVEVDGEATPDEVFDRIADVVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZL0</accession>
    <name>V6DZL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="9343" checksum="8E421E86D0972902" modified="2014-02-19" version="1">MRSERTESSRLGLRRSRSEGRLRRGWIRTAERLGLRKCSPERRHLLINSCQQHPILLEKVQRPRLHALIGRVRRGGRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZL3</accession>
    <name>V6DZL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_09651</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078151.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112466at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007003">
        <property type="entry name" value="DUF655"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40734">
        <property type="entry name" value="PTHR40734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04919">
        <property type="entry name" value="DUF655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="210" mass="23016" checksum="A7B2EF9B073CC0BE" modified="2014-02-19" version="1">MDHADGDGTPGDDRDGGGNAADTGADGVDDGGPTAVLLDVLLNGRPDDDRPQSRKSPVAYGLGTDSFALYELTLAGDVDVSVGDRIGVDGPAVGRYREVSFDDLTRNAAAEIEYAVEAVVEADEERFVDFYNEAGPITLRLHQLNLLPGIGKKLRNDLLDERKRGPFESFDDVEERISGLHRPQEVILERIVEEIREDDLKYRTFVGREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZL4</accession>
    <name>V6DZL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4134" checksum="48861E430DCD0C31" modified="2014-02-19" version="1">MRLAGVDVEVGEFAADVRVVALVAVTAVAGRDRRGVPLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZL8</accession>
    <name>V6DZL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5036" checksum="B73076D498A8AB03" modified="2014-02-19" version="1">MPNHAIAKPISASGGTGRSVRTSGAVRSSSRRRPPETGRTLRYKLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZL9</accession>
    <name>V6DZL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C488_09604</name>
        <name evidence="1" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6296" checksum="EBD41020ADE8240D" modified="2014-02-19" version="1">MAENSVPKVVVEEDVEVSVYALGCVGAIAAAYYTGQTGAWEPLMAVSIGLSLATLFVTSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZM3</accession>
    <name>V6DZM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6954" checksum="4591E9427F99844E" modified="2014-02-19" version="1">MAIPIGDSWFPVRVSKVNPSGGILTLGERRRDRGREWLPSLSIGVDNLRGGVLFPSCGYPRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZM4</accession>
    <name>V6DZM4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cysteine desulfurase</fullName>
            <ecNumber evidence="3 5">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_09591</name>
        <name evidence="7" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3 5"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078158.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24071at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="43"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="425" mass="46071" checksum="D99DB9929CF4C99F" modified="2014-02-19" version="1">MGVQGQYPFDVEALRADFPILDRKVGGDPETAGEGEGDDTPLVYLDNAATSHTPDPVVDTISDYYQSYNANVHRGIHQLSQEASVAYEEAHDAVADFIGAAGREEIVFTKNTTEAMNLVAYAWGLEELGPGDNVVLSEMEHHASLVTWQQIGKRTGADVRFIDVTDGGRLDMDHAAELIDDDTEMVSVVHVSNTLGTVNPIGELAELAHDRDALIFADAAQSVPTRPVDVEELGVDFLAFSGHKMCGPTGIGALYGREEILEGMQPYLYGGDMIRRVSFEDSTWEDLPWKFEAGTPSIAQGIGLAAAIEYLEEIGMDRIEAHEDLLAEYAYDELEALGGVEIYGPPGDDRGGLVAFNVDGVHAHDLSSILNDYGVAIRAGDHCTQPLHDEMGVAASARASFYFYNTVEEVDALVDAVREARDLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZM8</accession>
    <name>V6DZM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13612</name>
        <name evidence="2" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078164.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110148at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="122" mass="12760" checksum="89CD7535DF92A2AF" modified="2014-02-19" version="1">MKVLCGIGGSDDSFRALDRTVERAAVANDDLTIAVVDNEDSSVSPDEVADRATTAVDEAGIDAEVRRVEGDPGSRLVEIAETEGFEEIVLGGGHTSPMGKITIGSIAEFVLLNAKTSVTLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZM9</accession>
    <name>V6DZM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter (Putative substrate nitrate/nitrite) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nasB</name>
        <name evidence="9" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="6"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="432" mass="46006" checksum="3E1C85234042FF3E" modified="2014-02-19" version="1">MTKYRTLLLATVGFNFSFLIWFSFAPFTGPMAEEFGLSVAEIGILASAAIWLAPFGRILTGWLSDKFGAPAVFAIVLAYVGVFSMWSAVAESYAVFFGTRLIVATAGITFVIGIQHVSEWFDEAELGTAEGIYAGIGNAGAAGGALLLPRVFSTGWDGPLFSVNWRAAFFYTGVVSILLAVVYYVFGEAAKSDEKRRATAEGASFKEWVFTATRYGTVVLALAYVMTFGLELSMNGWLATYYREGFNTENLVLASTFAATFSVAAGLLRPIGGYVSDRLARAERNILPIFRGRYREQWTFVSLCFVVVTMFAMTLAGLSGRVALAVGTGFLVGMGCAFSEGAIFAQVPAMFPNSSGAVAGVVGGVGTVGGIVYPLVYAAPFLPNLHLGYSIVAVTMVPIVLLTAWVFQPHVAERATDAGFVGDDESAAVADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZN5</accession>
    <name>V6DZN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_09817</name>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4830" checksum="6B2974EB4D6DD41E" modified="2014-02-19" version="1">MKVQFECSCSEEISEFTRGETSRGVHVECGNCGAVYAVTITELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZN6</accession>
    <name>V6DZN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6538" checksum="1A7EC73A4E9E57F5" modified="2014-02-19" version="1">MDLGIEPRRDVDRDGDGSLDAVGAVGRDHDGVEHGRSLAGGVGKTRRSVRSESETFGNGSSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQR1</accession>
    <name>V6DQR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C460_00680</name>
        <name evidence="3" type="ORF">BN903_217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076336.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105481at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-1" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="14904" checksum="0723B582CCC4E1BD" modified="2014-02-19" version="1">MVAEKRFVSPDDVETIQLDWGTIKWMNTPSVTGAAEFSAGVVVLEPGKGHERHTHPDSEEILYFLSGEGEQTIADEKRTVGAGEMVHIPSGVEHSTINTSWEPLRFLAAYGPPGPEAEIREDEDATVFPPGEFPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQR4</accession>
    <name>V6DQR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8580" checksum="F4E983DF6E9494E6" modified="2014-02-19" version="1">MYVHLCNPHYFGQVIEYKANTDCFSQAVFRGEDRLTPAMSDTPTEEESDLIETRTRVPSEDDERDRIVTQTRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQR5</accession>
    <name>V6DQR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_01819</name>
        <name evidence="2" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="12028" checksum="97679B8E380AE35E" modified="2014-02-19" version="1">MAFITGLIHLVATTRAIEMSVVLAVLFVLNGLGFLGGAALHFTRFWRRSLFLVAAVYSLVTILALFPFRGWGIEAFYMHGGINPIVTITKVAEAFLVIVSAYLYRCSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQR7</accession>
    <name>V6DQR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6716" checksum="4A85383484E4A81F" modified="2014-02-19" version="1">MICSGKTILRLLLKLGTRIYLVLLSFLNTILNFDMIGLMSSNDSLKIVLSDRFSPEAAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQR8</accession>
    <name>V6DQR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_06317</name>
        <name evidence="2" type="ORF">BN903_166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076302.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="14803" checksum="59E66821579ACEE1" modified="2014-02-19" version="1">MSYLVATDGSTESDEAVRYAARQAVAFYETLEIAHVLTPDSELVDGTIILPGEEAAVEAGQGVLENARAVAEEAVGDESIDVETQLLTGRPADAITEYAADGAVDAIYVGHRGLSEEREQVVGSVAKSVVDKADVPVTVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQR9</accession>
    <name>V6DQR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GMP synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_06370</name>
        <name evidence="1" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5089" checksum="8657626642542419" modified="2014-02-19" version="1">MVSVMNSANFTVYKVSDGGFLPPVSTAGWRFDGIVISGSQTSVYDGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQS4</accession>
    <name>V6DQS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4868" checksum="A504C6536DB4424A" modified="2014-02-19" version="1">MDLRVGTYQISDLSGCRALDLQADHIAVRDDPSGVVGVVDDREPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQS5</accession>
    <name>V6DQS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4634" checksum="43AD5E677C344721" modified="2014-02-19" version="1">MVADSVLYLRFQAVQLYCVDCVAFCRLPPTTEVVGFRLVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQS6</accession>
    <name>V6DQS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="7110" checksum="ED6BEA3457D32ADA" modified="2014-02-19" version="1">MTVGFLGLQSLSTFIFRITEVYLDITVGWNEHTLSIEWYCSDRDFVELSAVDSATLSIAQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQS7</accession>
    <name>V6DQS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Adaptin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C480_22009</name>
        <name evidence="1" type="ORF">BN903_244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20008" checksum="54F6B8077AF2CEE3" modified="2014-02-19" version="1">MTAASLLGKVVVNHPDLVAPHVRTLVSGVQATEPAEFADIGEFVDHPGTLETIAEHERGERERRASARRMLVNVAVAVTETTPESAFDAVDPLAALLDDDDPEIVGGAVDALGELAAADPEVVAPAVDRLRDCLDHYDRSVRARSIRALGRRGDPDVVDELRTVAAEDDDETVRELAEETVTFLAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQT1</accession>
    <name>V6DQT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kinetochore-Ndc80 subunit Spc25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C468_04639</name>
        <name evidence="1" type="ORF">BN903_237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7748" checksum="5B9FDCCFE99A70FB" modified="2014-02-19" version="1">MFALAGYLVHDVHETVPFVLLDSLEAIDSDRIARVVDYFRTHADHLVAALLPEDAAALSEEYTYVENID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQT2</accession>
    <name>V6DQT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_03614</name>
        <name evidence="2" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10408" checksum="B9F2A42DFB077245" modified="2014-02-19" version="1">MSCEKRRVFGAAFVLLQGVVTAVFPQLSVKLAKKMIGKNFDNASDLEANPAYVRQLRALGVGMVAAGGTTLLLEGPQETESDLSKDSASDERSTESST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQT9</accession>
    <name>V6DQT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fused rhodanese domain-containing protein/hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_12826</name>
        <name evidence="2" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075840.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25677at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="27"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="397" mass="42824" checksum="15197F6975112DE9" modified="2014-02-19" version="1">MNADDFPTPDAEVASVEPETLKDRIDAGNDVTLLDTRMSSDYEEWRIDDDNVTSINVPYFEFLEDDIDDDVLDRIPDDREVTVLCAKGGASEYVAGTLVERGYEVDHLENGMNGWASIYETVEVSDYDGAGTLLQYQRPSSGCLGYLLYDDGEAAIVDPLRAFTDRYLDDADELGVDLKYALDTHVHADHISGVRDLDTAGVEGVIPEAAVDRGVTYADDLTNAADGDTFEVGDATIETVHTPGHTTGMTSYLVDGSLLATGDGLFVESVARPDLEEGDEGAPDAARMLYESLQERVLTLPDDTLIGGAHFSDAAEPAADGTYTATIGELVDEMDALTTDEDDFVDLILSDMPPRPANYEDIIATNLGQNVVDDEEAFTLELGPNNCAASQESLAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQU0</accession>
    <name>V6DQU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4728" checksum="3F10B7862ECCAC89" modified="2014-02-19" version="1">MITPFTLTEYYYLIINAIILCRCPRNSHSVSEQIQRSRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQU3</accession>
    <name>V6DQU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6278" checksum="2102644CE1776BA0" modified="2014-02-19" version="1">MSPAAPTAALVRRRYDRRVWSSRIHDPRTDTTMKGRVKMLTAHVKSPDYAYFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQU4</accession>
    <name>V6DQU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-flanked domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_2926</name>
        <name evidence="2" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5305" checksum="AE10155538732FAE" modified="2014-02-19" version="1">MSATTSKTDNTVNEQSTEEDNTSHNEFVSSKRRAENSPTDQKSDDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQU8</accession>
    <name>V6DQU8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thymidine kinase</fullName>
            <ecNumber evidence="2">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tdk</name>
        <name evidence="9" type="ORF">BN903_196</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11103" checksum="C14DAE82D0C34765" modified="2014-02-19" version="1">MIVSGTDQTFRGEPFEPLPQLMATAEYVDKLQAICSVCGEPASRNQRLIEGEPAHVDDPTILVGAEESYEARCRDCHVLLTGDRPEEERPFEGAEADPAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQU9</accession>
    <name>V6DQU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SOUL heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hlac_1279</name>
        <name evidence="3" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_haem-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="PTHR11220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK37930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="23996" checksum="B4B3056B59D60C5F" modified="2014-02-19" version="1">MRSVTKTILIGGGVALAGWVGWGIYSIKKAKSVPYEQLRTVNDTEIRRYPQTVLVETTAPTQRIAFQRLFRYISGANQGNESTSMTAPVETQSRDSIAMTTPVRSEATETGAETIRMAFYLPSEYTPETAPEPTEPDVRLITEPQKTVAVDQFSWYAPEWRVTRRTQKLLSTLEGEDIEPEEDPYLLRYNDPWTPPFMRRNEVAVEVVEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQV1</accession>
    <name>V6DQV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00967</name>
        <name evidence="2" type="ORF">BN903_201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076328.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="6870" checksum="179D4667E6C26026" modified="2014-02-19" version="1">MDPSDRALLGVAGIVGALVLAVAFAGGYLFGFDESAARPIRLLAVEPLTWIVVAALVVAVVGNAYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQV3</accession>
    <name>V6DQV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_00262</name>
        <name evidence="2" type="ORF">BN903_135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075845.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47092at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="112"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="273" mass="31479" checksum="BC69282D32654F25" modified="2014-02-19" version="1">MKALPKSQILRFTEKAINLARRAVSRYSSKFSKHRYTLPQHVVLLCLKVRKNTTYRGLLDELIEMPRIRRALGLAELPTPSTLCKAFNRLDMAVWRVILTLSATLLPTSGIVGVDASGFDRSHASKHYTKRAKLTIQQLKVTLLVDAKMNAILDLHVTTTRKHDSQIAPSLIKRNPETINILLGDKGYDDQKIRRLARQHEVRPLIKHREFTSLHKAWNARLDADLYGQRSQSETVNSTLKRKYGAFVRSRHWWKQFRELTIACLVHNLDRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQV4</accession>
    <name>V6DQV4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Usp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HSB1_40970</name>
        <name evidence="2" type="ORF">BN903_257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076359.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114597at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="6"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16841" checksum="EA5ACBB69C4A2666" modified="2014-02-19" version="1">MEDAFVAIDDPDHSSDLLREAAAYAVGADAELVLYFPLTPEEFEESQESLDKIGRVEHKDYGDEDAQTVAKQFVDDIAREPLADFDVEYSVVTDVTEEIDAGRIIELAEERGCDHVYTTGRRRSPTGKAMFGDTTQQLILNFSGFVTVRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQV5</accession>
    <name>V6DQV5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8 9">Uridine kinase</fullName>
            <ecNumber evidence="4 8 9">2.7.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Uridine monophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">udk</name>
        <name evidence="11" type="ORF">BN903_206</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + cytidine = ADP + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>ATP + uridine = ADP + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 9">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076332.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70045at2157"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00551">
        <property type="entry name" value="Uridine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026008">
        <property type="entry name" value="Uridine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="10">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK38531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="232" mass="26507" checksum="0DA23E14928FE88F" modified="2014-02-19" version="1">MAIPSFVIGIAGGTGAGKTTVSRLVTRDLGDSVTRIPLDNYYEDLSHLDFEERQEVNYDHPSAFEWELLREHLESLLEGQSVQMPQYDFEVHNRKDERITVEPTDVIVLEGILALYDEEINDMMDLRLFVETDADVRILRRIRRDVIDRGRDLEGVIDQYLSTVKPMHEQFIEPSKKHADVIIPEGANSVAVNLLEEKLRAEVEGDAVRSWERGSLEQELGEKRSLDVDGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQV7</accession>
    <name>V6DQV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_3093</name>
        <name evidence="2" type="ORF">BN903_140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075848.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125851at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="11024" checksum="0E7A4ABB0EE2BD9C" modified="2014-02-19" version="1">MSEEWDWKLTDRSKRQLDALDEYARDRIISKLEEVVTDQWREPTDHLEPLTGAPHQKLRVGQFRLGCRADREQRILYVVAIRKRGGNAYRGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQV9</accession>
    <name>V6DQV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="184" mass="20882" checksum="CE920A1006F002CF" modified="2014-02-19" version="1">MWSGWVAADSVPVLVRIRPELDEQLLHPRELDVVEIASCGVMLVPLRVLVGVVVPDEREIVEGAQMERVLPARGVRSRCRQSVEARRSRRGRFRRACTGRAALRASLTCWDTSQQHKRWAEVQHRTETPLVPQRPLIGLPHRSKPSPESPLNQPLLPGWCLRHLNNTPSQPHICTQYAIGSMLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQW2</accession>
    <name>V6DQW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="5">3.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Halxa_3774</name>
        <name evidence="5" type="ORF">BN903_270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076366.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43138at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="PTHR31490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="GH10" evidence="4">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="34175" checksum="9DBE67D78A5D0452" modified="2014-02-19" version="1">MRTLRDAAAEADLHVGAAVDVESLRTNTDYRETVAREFDAVTAENAMKWGPLADGESGYDFAAAADVVDFAARHDMYVRGHTLVWHRMYPQWVRPWARSDAEMRRLLSDHIHTVAGRYRGRVDAWDVVNEAVADDGGLRENAWLNALGPEYIDRAFEHAAAVSDADLFYNDYGADGLSAKADEVYELVSDLVAREVPVDGVGLQLHVFDDVVPPADVAANVERLTDLGLDVHITGLDVGIGEAVADRDEQAEYYYDVVSAAVDAGVDTVVTWGVDDGQSWLPARGFGDAPLLFDEEFRRKPAHGAVLDALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQW3</accession>
    <name>V6DQW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HalDL1DRAFT_1102</name>
        <name evidence="2" type="ORF">BN903_145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075853.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62026at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041113">
        <property type="entry name" value="Heliorhodopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18761">
        <property type="entry name" value="Heliorhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="241" mass="27155" checksum="C9F8C9417124FDFA" modified="2014-02-19" version="1">MAVLHFLQGLAMVLLAEGVLWPITRTRYGFNPETESIFPETVSFIDANLPLLVAGFLFISALAHAIIATNRYEAYVAYLDRGMNPYRWYEYSVSASLMIVVIGMLAGVWDLGTLVALFGLVAVMNLCGLLMEQRNESTDKTDWTPFWVGVIAGIVPWIVIAITFIGSVTASAGEFPQFVIYIYFSIFVFFNLFTLNMALQYLEVSRWKNYLFGERMYIVLSLVAKSVLAWQVYFGTLNSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQW4</accession>
    <name>V6DQW4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5574" checksum="B9867C7E4C252171" modified="2014-02-19" version="1">MNTYLPNYFNFVEAVTVNEWFRSFASHGLSASKYDRTIDTNVFNRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQW6</accession>
    <name>V6DQW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_01750</name>
        <name evidence="2" type="ORF">BN903_150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075857.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113414at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK37950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11135" checksum="E2C6BF977C9BBC13" modified="2014-02-19" version="1">MSTETSTNDDVRSGRTITLTQADDGWWVARDEATGVASQGETRQDALDNLDEAVALHKGETGDSVDNWEEEKEVLDELGIDPDEVQQARDEHDDLPDFMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQW7</accession>
    <name>V6DQW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Branched-chain amino acid ABC transporter ATP-binding protein</fullName>
            <ecNumber evidence="5">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C471_00055</name>
        <name evidence="5" type="ORF">BN903_221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076340.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58905at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="252" mass="27586" checksum="A792E0A5AAAE6125" modified="2014-02-19" version="1">MALLETDELTKEFGGLTALKDVDIAVEEGELVSLIGPNGAGKSTLINTITGRLTPTEGTVTYAGTELVGMEPFEIAQLGVGRTFQTASILPELTVRENVQVAAFAAEHGSFRINFLSRRDSFDEVQRLTDDILDTIELDDKSETKAASLPYGDKRRLEVAIGLATDPDLLFMDEPTAGMSPAETEMTVDLIENLQSEWGITIFLVEHDMDIVFNISDRIFTLHQGELIAKGTPDEIRDHPAVREAYLGGEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY0</accession>
    <name>V6DQY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="9508" checksum="B1485121A10A7F02" modified="2014-02-19" version="1">MKSESSSSAVSRTTLPGWTVFTEVENPFAMELLWGTPAASARRATESVNASESSATSLSSTTPWSIARTTSSSSTYSAWTLASYSAATAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQY3</accession>
    <name>V6DQY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="6016" checksum="60CCE963D9FCB54B" modified="2014-02-19" version="1">MFDIFNHRYSGGVLYNDRVVYSDIENKAVVVSVFRYRRFVAVNTRRHPNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR32</accession>
    <name>V6DR32_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_12135</name>
        <name evidence="2" type="ORF">BN903_230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075910.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="SSF47802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="314" mass="36034" checksum="D26AFE926C680432" modified="2014-02-19" version="1">MIDTENPAEEQQPQSNIPECTLPETVSGWTSRTTKPGNILEYWRKGCTHIACSFEQLVARQRGDGDITLVKRCYDKYRHLLNTQSISQHDPSNFDWICDQAKQRMERYPGIEPFTEPPTFPTGVGEWDAVSLPKEQPIGLAKWELGLGRAELFCEETEIISHYSHTRRPHTVSYRELDTESTTIAKGVSKTMAYEIAVNTLESLPRPVSEMGETKRDLQEIKGIGPAKSRNLILLGVTSREQLREHIQSENNPINHHHSKAVSKLLTETIEDDLTTTDQSKYPHTHPRRRRTDPERNRDRRPARTVTEARRDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR35</accession>
    <name>V6DR35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5388" checksum="AD05F1B11A80F0E0" modified="2014-02-19" version="1">MALSLPATIAYSFIAAAVVGFSFSLLTDRVSVKMGFLMAVCTTAGTVVGRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR38</accession>
    <name>V6DR38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4835" checksum="EFD9D71A177927A1" modified="2014-02-19" version="1">MTCGTGSDTRASRRQNASTTTSTGCSSSTRDHYSKSLDLSDFPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR39</accession>
    <name>V6DR39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4330" checksum="E9E34C0466EC0226" modified="2014-02-19" version="1">MTTLLAVLSSAMSPGGLYGLHDGPQRDGFAVGSTPCGSETEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR42</accession>
    <name>V6DR42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3982" checksum="9D98238E916052E9" modified="2014-02-19" version="1">MCSDDSRLLGRIVNPTKTGFVGGTVDSAEVTELTVGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR44</accession>
    <name>V6DR44_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08145</name>
        <name evidence="2" type="ORF">BN903_291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="114"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="360" mass="38871" checksum="62A212D6BF66346B" modified="2014-02-19" version="1">MVTVPTVGVTDVGIVGAGAGAAAAAFVIDRTVPDADVTVVEKSGGLCGRAATRRYDDLTYDYGANYLKSDDDRVVELITETLDDEGLVDATEPVYTFDVDGTVSPGRDADEHKWSYRRGLTQIAKRLFGRTDATVHRRTRVETVRRVDGANPTDDGRWELDDADGETHGPFDVLLMNPPAPQTADLLRTAEWDDPLRETLVEAVGAVEYGSVWTAVLHYPFALDVPYYALVNTDKEHAVGWVSREECKAGHVPDGETLLVVQAGGAWSATHYDDDPAENVAALAAHTADILGDERLADPAWTDHQGWRYALPEDGVDRGPVDSARDAGLYLLGDWVAGEGRLHAALANGLDVGERVAYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR50</accession>
    <name>V6DR50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="7958" checksum="D467564A49449027" modified="2014-02-19" version="1">MRSLTTNSSSRSFAASSASLRPCPTTRSYSTAGRCETQLLIASRTRSPGSVTEAYSAVSRSKKASSAWVTYRGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR51</accession>
    <name>V6DR51_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps11p</name>
        <name evidence="4" type="synonym">rps11</name>
        <name evidence="6" type="ORF">BN903_354</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Located on the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004595254.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="34508617"/>
    <dbReference type="GeneID" id="64827084"/>
    <dbReference type="OrthoDB" id="114285at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019961">
        <property type="entry name" value="Ribosomal_S11_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03628">
        <property type="entry name" value="arch_S11P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="13611" checksum="A434988FD6521CFF" modified="2014-02-19" version="1">MSESEDGGKWGIAHVYASFNNTLITVTDETGAETIAKSSGGTVVKQNRDEASPYAAMQMAEVVAERVKDAGLEGVHVRVRGPGGNLNKSTGPGAQATIRALSRAGVEIGRIEDVTPIPHDGTKAPKNKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR56</accession>
    <name>V6DR56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075923.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="14783" checksum="452DA8F97A4A4319" modified="2014-02-19" version="1">MAHHDIPDLPSGWVVSTNIEEHISLLRAEGETRYSIAIYPTNPATTRSGWTVMGLANYEPFRPVFTENASLEDALSTAIDEITAKINGEQIAHVRKAGSDQDAEPTDNPEPESADEDTETDSDSSDGQSDLNHWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR59</accession>
    <name>V6DR59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_00659</name>
        <name evidence="1" type="ORF">BN903_362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076433.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80443at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="224" mass="25096" checksum="B05278AAB425331D" modified="2014-02-19" version="1">MDLRESTLRDRAREYAAAEPLYDVECQHVETVPKTFAGDEYGRRDAQWIVRWYFRRYLGEFPDRERREREEAFRDNAFDDVVDALDAAVNALDVADALDAADVLDTAGAVESEPADSGADRDADSDVDVALDALTDLDGVDVAVASGFLQFLAPSRFVAVDRRTWAVLAAAGELDGDYPEPPSTVDYRRFDDACRTVMERTGVDAWTLYRALWRSFAELPEPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR61</accession>
    <name>V6DR61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C435_03278</name>
        <name evidence="1" type="ORF">BN903_250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075928.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="246" mass="27169" checksum="CE3B557F71E72F74" modified="2014-02-19" version="1">MSESSTTIGDFELAGAPTSVEQISESAPAHVLEAFSALSSWGTGVIINEIDEPLLVGAETDDHTKSYRLYHGPSADHGLQFAGVLAHSHSYSDEIPDRVGFVPAGDGPDEPTEVAPIETLDVTDHDRTARLDELLPYIRTEITDSDWVNGRGDTTYPEWGQAVRRMAEFMRNDLDAELAFDRQLLRLPRVEHALGRYPLDAESILTQFSNTIDQKSKLDHHSESPEAFRELLFAFAAHHDITGGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR62</accession>
    <name>V6DR62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C461_07899</name>
        <name evidence="2" type="ORF">BN903_311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16784" checksum="98079F50DC4CDC50" modified="2014-02-19" version="1">MDVSDAEAASGDGSLRIWNQGDYDDGVTWAVHPVPVESGGSYQIEVSGQFWSESESFNTIRHALMRLGPEPPETEEEFPQPGLNTTDLGETPYGGLRDSLWLADGWREYAFEWTTPELSTDTLYLAVGTAVIWEADATHYVDDLSVRVEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR64</accession>
    <name>V6DR64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01669</name>
        <name evidence="2" type="ORF">BN903_368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076438.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="142909at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="7166" checksum="5C188D3B80D57B31" modified="2014-02-19" version="1">MVPKHLIWIGGLLIAIPLFLALLSAAWIWVPIGLFVLGIGVVLYGFKQYHEKRMRDRFERSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR66</accession>
    <name>V6DR66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08038</name>
        <name evidence="1" type="ORF">BN903_316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076400.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103543at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043852">
        <property type="entry name" value="DUF5814"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19131">
        <property type="entry name" value="DUF5814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16909" checksum="A1FB79A52E249C51" modified="2014-02-19" version="1">MAFTDKIYVKNHRQLASQLETNIPKGAFAGATLDLLFTGDGLSKLDETTRDRVLDFAEDFLDCTCDANPYCGCPEEKFMRYVLELRAEGLGPQAIVDVMTDDYMVYAYTGDVLSFLDDSVRKLEAIETLADVDGNGEMSERARKRKRELSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR67</accession>
    <name>V6DR67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075933.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="225" mass="25538" checksum="9C1187854D3486FE" modified="2014-02-19" version="1">MESNHSHSDDTDAAVLAPSPEYLICLAELSPANLKLYNTETEQFVRVVPSDQEFEMEHRAGPEQPWEHQSTGTDLKAIVREATDVLDLAVTTKTCPQTGLEDLYIDTGEHGQLLIDDRDQFPVHIVKKHPNPFDPTNEEFLIEAPNKQGESIPNHYSYHVHTRHCIEDEWEAPHSCYEELSPAAAMDRFSAITDLDTLMIDEEEEPTEVFQEPHETETESPNTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR71</accession>
    <name>V6DR71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08008</name>
        <name evidence="1" type="ORF">BN903_321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8109" checksum="D65C2C78F3EDD124" modified="2014-02-19" version="1">MSLPTDWMTRWEISFIGSRGMPPTSYPDLFALIEATDIDPGALVTSELSLSEVSGRLAAMEEYDARGVEVVTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR72</accession>
    <name>V6DR72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075936.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10905" checksum="3770AA9F47936163" modified="2014-02-19" version="1">MTNIKSLKELKRSNITRYEHTRTGEAKRIHTIDIRGKREDPKLVGSVVTIDEDGQSDEIDAQEFQNQLALEIIKPLPDTNSETSTLDSFENTPAGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR76</accession>
    <name>V6DR76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_00547</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076498.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006276">
        <property type="entry name" value="UspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="144" mass="15251" checksum="D36D0C00131BA906" modified="2014-02-19" version="1">MYSEILVPTDGSPASDAAIEHAIDLADRYDARLHALYVVDGGAYSSLEAGAEVVVDALESEGEEATRQVADAAADAGVDCVTTVTSGTAYQSIHDYVDEHGIDVVVMGTHGRKGLDRYLLGSVTERVVRTSDVPVLTVRQPTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR77</accession>
    <name>V6DR77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075939.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="145" mass="16512" checksum="244672CFB81D1150" modified="2014-02-19" version="1">MSSRHTHIAEDRAVHVVDDGEFEQELTETADPNEVLAFICQLVEWYESDVDHRDELPLFATVVNDGCVYIRDAQGGEWLTWTVDEWTLPPEEGQASDGDYSLEDTDRRLNTDVIRPIINAIATTYESPSEIKQRHDCTQIESCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR79</accession>
    <name>V6DR79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_15988</name>
        <name evidence="1" type="ORF">BN903_331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076415.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116806at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="14496" checksum="E014B1CCF551C479" modified="2014-02-19" version="1">MAKTRSTSEESWEELVRNADGTIPDPVGFGPSERVEIETRYLDKTAKALKFPLDHVYCLHESDFAVALNPDLDVGKLVLTSHETWDEHRFRVTMPDAVTDEFYERLEMYERVSPERFGVEQSSVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR80</accession>
    <name>V6DR80_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">gcvH</name>
        <name evidence="6" type="ORF">BN903_379</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076445.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96879at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="13777" checksum="CF2C1551968330F7" modified="2014-02-19" version="1">MSFDVPDDRRYLESHEWATTGGDPVRIGVSDFAQDELGDVVFVELPEVGDEVVAGEAFGVVESIKAVSDLYAPVSGEVVAVNEELFDRPELVNEDPYGDGWLLEVEPVEGGEADGLLDADEYDDQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR81</accession>
    <name>V6DR81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA methylase, NOL1/NOP2/sun family protein</fullName>
            <ecNumber evidence="6">2.1.1.178</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_12171</name>
        <name evidence="6" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.178" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076502.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32049at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="17"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="106"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="321" mass="34565" checksum="585CECE2B4B780AF" modified="2014-02-19" version="1">MNPLDRYESLVDDVDAFRAACDRPLPSVVRTNEIAATPARVREAFDEAGVAYEAVDWHDGLFRLPDGNPGGNWPYVHGWTHGQEEVSVLPGLALDPQQGERVWDACAAPGSKTTQIADAMADEGTVVANDNNLGRLSALRHNAERLGITNAVVTNQDARNFSMKPLAFDEFDRALVDAPCSCEGTCRKNPDVLDEWTLDHVHAVAGIQKGVLARAVQATRPGGVVVYSTCTFAPEENEAVLDHVLANEGCELVDFDLPVETDPGVTEWDGETYDESVTQAKRIYPHRNDTGGFFCAKLRVGGESEDGVSDGGAADDGEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR83</accession>
    <name>V6DR83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C484_16389</name>
        <name evidence="1" type="ORF">BN903_270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5081" checksum="DB74D76568EF2418" modified="2014-02-19" version="1">MKEALDDKNVAADFYDALDGEVEELISDAAARAEANDRKTVQPRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR86</accession>
    <name>V6DR86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9909" checksum="5C8D8C87B2EF1BE8" modified="2014-02-19" version="1">MSHRKAGVHDRVTCAVPVCTNDILYVSVGGRRRSRDRRRYADARNAFYERPSSVIHDNIPRETRYQSSGLINNKSCIWLIDYPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DR87</accession>
    <name>V6DR87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5830" checksum="D536BDA84CB50D49" modified="2014-02-19" version="1">MRGLDVELVVRVEQRPVHRLLRAEVLHDRHHLFVEFEQLVFVHALGYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV7</accession>
    <name>V6DTV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_11155</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="208" mass="22589" checksum="98E6161C98F844B9" modified="2014-02-19" version="1">MNLTDCFTDGDSDDSNDTVGSITVPLTDDNREFIASQAGDRNASYEEGKTTNEIWGDGDSASKHEIGFAGELAIAGLYESASIDTSVSASGDGGVDTEMRIEGETRTVDVKSATYDGPGASIMVQQDHAERFTTVLPEVYISCYVPDDLSCVKIRGWEYADEVILESNLKDAPGGDWINYDVACDDLRNMVEPTGDELTEDEDYHVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU76</accession>
    <name>V6DU76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate ferredoxin/flavodoxin oxidoreductase subunit beta</fullName>
            <ecNumber evidence="4">1.2.7.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C464_07785</name>
        <name evidence="4" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.3" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077321.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43666at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047553">
        <property type="term" value="F:2-oxoglutarate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011896">
        <property type="entry name" value="OFOB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02177">
        <property type="entry name" value="PorB_KorB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="3">
        <location>
            <begin position="61"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="34684" checksum="EB966EE38CA25B77" modified="2014-02-19" version="1">MSTFSAIGEEREIDRDEYTPGVEPQPTWCPGCGDFSVLKALKQALPEVGRTPEETLLCTGIGCSGKLNSYLDTYGFHTIHGRSLPVARAAKLANPDLEVIAAGGDGDGYGIGGNHFLHTARENHDMTYIVFNNEIFGLTKGQTSPTSPKGHKSKTQPSGSAKEPLKPLSLSLNAGASYVARTAAVNPNQAKEIIVEAIEHDGFAHVDFLTQCPTWNKDARQYVPYIDVNDSDDYEFDKTDRVEAAEMMRETEESLHEGEVLTGRFYVDEDRPSYGEEKQAIGEMPEEPLAERYWDDDYEWERSHDMFLDKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU77</accession>
    <name>V6DU77_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Ribosome biogenesis protein Nop10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">nop10</name>
        <name evidence="9" type="ORF">BN903_131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NOP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077288.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130364at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00803">
        <property type="entry name" value="Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023532">
        <property type="entry name" value="Nop10_arc-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="SSF144210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6808" checksum="EB8310E68547D82D" modified="2014-02-19" version="1">MKSDIRVCANWEAVHDRPVYALGDRCPECDGPTENSAPAPFGPEDPYGEYRRRARRRGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ0</accession>
    <name>V6DUZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Non-histone chromosomal MC1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C471_08180</name>
        <name evidence="4" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protects DNA against thermal denaturation and modulates transcription.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077542.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113390at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008674">
        <property type="entry name" value="MC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036620">
        <property type="entry name" value="MC1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05854">
        <property type="entry name" value="MC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102875">
        <property type="entry name" value="SSF102875"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MC1" evidence="3">
        <location>
            <begin position="7"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="12516" checksum="FC791E2C4E89F78E" modified="2014-02-19" version="1">MVREDGKRNFALREEDGSEPSEFSGNMPRQAALKAARTLDPAPSEDEAERTTLRLREKGTRKVHEYEGWAWKDSAPEVDEAEEDFWLNDLDDITKANVSKQGIEYLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ1</accession>
    <name>V6DUZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mannonate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C471_08750</name>
        <name evidence="4" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008927">
        <property type="term" value="F:mannonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006064">
        <property type="term" value="P:glucuronate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004628">
        <property type="entry name" value="Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30387">
        <property type="entry name" value="PTHR30387"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03786">
        <property type="entry name" value="UxuA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016049">
        <property type="entry name" value="Man_dehyd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="337" mass="37492" checksum="55E88DE7B6E4660F" modified="2014-02-19" version="1">MVQLSLILPPEPDDRWHLARQMGVTSAVVHPLEIGDNKTNWTYDELKGMTNWFEEVGLDLSVIEGSVPLTDRIRLGLDGRDEDIAEFKQFLRDCGAVGIPVVCYDWMAGVRWARTEAHVETRGGAYTTGYTDERMSGGPPIDEDVNRDQLWEALEYFLTEVIPVAEEAGVKLGLHPADPPIDSVRGIPRLANSVESYDRILDIVDSEHNGVTFCQGNFAAMGVDVPETIRHFGDRINFAHFRDVEGEADDFVETWHDDGPTDMLAAMQAFEDVGFDGPMRPDHVPTMVGEDNSNPGYHTKGRLFAIGYMRGLLEQTTANRQGDADHEAAFNPETVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ2</accession>
    <name>V6DUZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_13150</name>
        <name evidence="2" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="22576" checksum="86897F2DBB3D5AE3" modified="2014-02-19" version="1">MTTSDPPENLWEGDVNEAVVEQWTDDTTAFDRVRQAVDVTTEPQSAAAIADRARVSPPTARKYLSTMAADGRVKRINTDTGSQYMRAPQMLAMRRIAAIHREHTKAEIRSSIKELQEERASIKETHDVGTIDELTLALDAGDDGWEDVARWRQIEQNLEIAQAALALYGFDPDDSHAAAVSTAESTTERRERGAFGDDTSRSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ3</accession>
    <name>V6DUZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_03066</name>
        <name evidence="3" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="10844" checksum="56FA8CC53DD650EB" modified="2014-02-19" version="1">MIQVVAAIQVLAGIALLVASAVADLGTIVAPAMGIVFLLVGGFLFAMVANARLSDRFRSEEYRDRLRALREAKERPEFVPVEDGVVTDEAPGESDRDRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ4</accession>
    <name>V6DUZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07570</name>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077545.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="127736at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="9413" checksum="61EF25ECBFD536D0" modified="2014-02-19" version="1">MTTVWLVDRQFDSKGLVRLTYATEDGERMHTKELAEQRLVTGDGITAGREVEETALGESPADEVERFTTEASKMAAEHDLDDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ5</accession>
    <name>V6DUZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07754</name>
        <name evidence="3" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077527.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128544at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="10282" checksum="C3012CB63D6B99E9" modified="2014-02-19" version="1">MVDFGTVYLIATGAALLFALGVGLRVLAGVFRDGRERSRKRREGEVERYTEDPVYDRDPPDADAGGQRICPQCGAENASEFVYCSECAAPLGPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ6</accession>
    <name>V6DUZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
            <ecNumber evidence="3">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C471_08730</name>
        <name evidence="3" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076801.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43299at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="287" mass="32851" checksum="C192183736642D6E" modified="2014-02-19" version="1">MNVLVTGSYGRCGTAIIDHLDDNPDYEFTYLNRSDRPSDHRYGGFDTHVADITDYDAIRPAFEDQDAVVHLAAYPYTDGAWEDVFEPNIIGMYNAIEAARDAGVDAFVFASTNHVMGMYEEEHAPELYEPDYDLRLDPTDRVRPDSCYGATKSFGEDLGRYYTERYEYPRRFYALRICSVLPHGIDHPYGRAERRVENGEIERGSDAYDRSVARTKATWHSRRDFAHLVERCLADGSVTFDVFNAVSDNDRRWFSIRNARGRLGYDPDDNGEAWDGPPIEHEHEGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ7</accession>
    <name>V6DUZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_14025</name>
        <name evidence="1" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000009">
        <property type="protein sequence ID" value="CDK39971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5703" checksum="BB0EEB8AABB91CF7" modified="2014-02-19" version="1">MPSTMEVKCVSDDCELDMFENHYTYDVPDDHAVADLSCPYCGGSELVEIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ8</accession>
    <name>V6DUZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C444_16913</name>
        <name evidence="2" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000005">
        <property type="protein sequence ID" value="CDK39350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077099.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000005.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84707at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="191" mass="21865" checksum="17F7376CE6CA9D49" modified="2014-02-19" version="1">MDLTDIPGEAYTDDESPPDLDELDTPDSLLKSGPIRERLLDSVIGLRTPTKVSTIADRADCDTETARDYLGWFHEMGLVHRHDGHPVRYKRNDAYFQWRRRNKIREDYSDQEIVDALAATLEAIDAYRTQFDAQHPDEVSLVNATREQDLSTEAAWEALSEWETLERRAALLDTARRTDPVSRRTPGHVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUZ9</accession>
    <name>V6DUZ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
            <ecNumber evidence="1">2.7.1.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_06154</name>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.60" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000010">
        <property type="protein sequence ID" value="CDK40012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077530.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000010.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61440at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009384">
        <property type="term" value="F:N-acylmannosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="325" mass="33864" checksum="1AF5CE83C730C07A" modified="2014-02-19" version="1">MYYVGVDLGATNVRAVVGDETAAILGSASRGTPRGPNGIAVTEAVLEVIRGACTEAGIAPSEPVAAGIGSIGPLDLAEGVVQGPANLPDTVERIPLVGPVGRLLDTDEVYLHNDTIAGVIGERFHSERNPDDMVYLTISSGIGAGVAVDGNVLSGWDGNAGEVGHMTVDPHGFMTCGCGLDGHWEGYCSGNNIPHYARELYEEDPIETSLPVEDPDFSAVDVFEAAGEDTFADHVIDQVAHWNAMGIANVIHAYAPLVVTIGGAVALNNPERVLDPIREKLPEMVFINVPEVRLTDLGDEVVVKGALASALTGGTGDRSRVESPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB2</accession>
    <name>V6DVB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_3625</name>
        <name evidence="1" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="193" mass="22545" checksum="037CF998BCA3B10B" modified="2014-02-19" version="1">MGSSNSDPEKIVEQQPVPKCIGKRWEEAVRNSLIRAGYKAERTAWLWGFEGDVIARYQGENQPQKLYVQCKYTETDEKIMPKDMWRLIAFSFSLHAEPVLATNMCLTGDAEEIAESWKVRILRPSSLDRPDRIKPHSTENRSRNLDQFPDLMESDVPLSDVVAPRYSHRDLVGDREIVFQRKKTDFPSERWWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB3</accession>
    <name>V6DVB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077614.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11440" checksum="91E0F9ED0AF166CC" modified="2014-02-19" version="1">MGGEPSLKELVEAALLIVVLIGVIALFTLTDFDSVQQSSNNLSRFIWAVTHIAVPTTRFAVYFEMALAVVGGITIERIDARATIIGGFALYFFINFVDAWFAAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB4</accession>
    <name>V6DVB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NP_6012A</name>
        <name evidence="1" type="ORF">BN903_161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6464" checksum="D984D33CBF2D4F35" modified="2014-02-19" version="1">MSGRRLRTVVADTSALVSLAVPRVDAAVGTDIADPFQYLLTSCEVFVPTEVVAELRDITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB5</accession>
    <name>V6DVB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C486_16905</name>
        <name evidence="3" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11724" checksum="CF040E10F0930D39" modified="2014-02-19" version="1">MLTFLPTESRYYIMDAYAVSYDLNEPEQEYTELIDALESYEAHWHELTSFWLLDTDESHTEIRDNLKQYIDSNDEILVLGLSGSAAASSINDWDWIEEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB6</accession>
    <name>V6DVB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AbrB family transcription regulator domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">OE_6070R</name>
        <name evidence="3" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="34"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12285" checksum="FB9FFF30C79AE9CE" modified="2014-02-19" version="1">MPSKPLSEINNVLHKSERSITGPYLLHMSDSENGTTVNVTSKGQATIPKEFRDKLHIDTPGRVRFVEADGEIVVKPVKRPSEIRGALAAEETDGETSATKMLLKARKRDSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DVB7</accession>
    <name>V6DVB7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_14161</name>
        <name evidence="8" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Potential transporter for phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Membrane</location>
            <topology evidence="2 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077619.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40216at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="387" mass="39461" checksum="4730E31EECE919F4" modified="2014-02-19" version="1">MVEILLLVGVTVAAFVGYNIGGATTGPAFGPAVGADVLSKSGAAALMSVFFFIGAGTLGQRVVTTLGEDLVSGANVFTLETSIVVLFFIGGALFVGNFAGVPASTSMTAVGAIAGLGLATNTLNWAEMGEIAIWWLVAPIIGFWVSGIVGRYFYSTINDWVAIDSTEGALFEFDRSGLVPKPVPGPNTTRRELFGGFVVIAIGCLMAFASGTSNIANAIAPLVGAGVEIRPLILLGSAAVAVGAFTIARRTLDTLGNDITDLPLTAAIVVAVVSSGIVISLSAVGIPASFVIIATMSIVGLGWGRATRTVTVRQGIRGEKEPTVSVGALAADEMPDIGEGDASDVPSASDLFNPGTSARVVLMQNVVPILSTVGALVTFTALFTFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZC1</accession>
    <name>V6DZC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arsenite transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C498_00115</name>
        <name evidence="8" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="7">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="241" mass="25552" checksum="26539ABCC69BD5F2" modified="2014-02-19" version="1">MLVVLLIILGAIVMFVTEWLPIDVTAIGIMVTLIVLEPWTQITPAEGISGFSSSATITVLAMLILSAGISQTGVVQIIGRKISSFAGDSLNKQLLATIGVAGPTSGFINNTPVVAILVPVISDIAHKGKTSPSKLLIPLSFASMLGGTLTLIGTSTNILASDTAARLSGEYPELHAFDFFEFTILGVIVLITGSVYLLTIGHRLLPERVPVEDDYVEEYEIADYLAGSRRPRAFAAGRANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZC2</accession>
    <name>V6DZC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6462" checksum="63CB0C203062159F" modified="2014-02-19" version="1">MSSDTVSTTRRRTSPNSLRSPRLASVTLRELFPHGSGYQGSKSMRQPSRWLASVVLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZC4</accession>
    <name>V6DZC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar phosphate isomerase/epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_14592</name>
        <name evidence="3" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="30"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="315" mass="34474" checksum="FCF1CCECC16BAAB0" modified="2014-02-19" version="1">MRASDMTSPRTAFQLYSVRSDPDSLPDVVRRVAASGYDGVEFAHRFRREPSEEVAAALDDTGLAPAAVHADLPTIEAALAGEDDLLERCATVDCDRIVVAHPDSTHFHTRESVRALADRLNDAATALDDRGVELGVHNDRRWLSPLLPGGVETLIDATPIPDGSDEYLQEATRRLRARNAGKIPRRTPLWQLIAETDPGAVWFELDVAELRAGGVAPTEALSLLDDRVKMLHLRDVTPGPGLDDYESVPHGDGVVDMEGALDVAGDADLEWLVYENELDTPPETKIDDGRRFFDRMPGERSPTNGSVSLRAQAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZC6</accession>
    <name>V6DZC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphate/sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C495_08205</name>
        <name evidence="9" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Potential transporter for phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="35668" checksum="A5D7444614C97112" modified="2014-02-19" version="1">MTFFVFLGGITVGRNVMDTLAGDIISIPITLEAGVGVLFFIGLGILIANVFGVPVPTSMTTVASIAGLGLATGTLNYETIGSIVSWWIVTPIIGFWIGAIIGRYVYPELERRYAIEVSDGPLLSLDRSGRIPRPTYGPNTDRREFVSTVAVLMIGCYMAFSAGASNVPNAVAPLVSSNAIDEVNAIALATVAIGIGGFTIARRTMESVGTELSDIPLLAALIVMSTAATITTALSAAGIPISLVMAMVMTIVGLGWGRATRPVTARDALGGQTQNPIATGAITADNGDTARPIGQPESRKALNTGNLFNPRAILKYVSMWILGPSVALALSYAFFVVVPFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZC7</accession>
    <name>V6DZC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HSB1_41630</name>
        <name evidence="3" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078114.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72347at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="2">
        <location>
            <begin position="14"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="266" mass="29421" checksum="47C88BB2255FFF07" modified="2014-02-19" version="1">MDTSDNVEDAVQILQQLGLKEYEARCFVGLTRLDTGTAKKLSEITEVPRTRVYDAIRVLEAQGLVEVQHSSPQQFRAVPLAEATETLRDQYEERVERLHDALDTIEIVDEGDRSAVQQIWAISGHEAINNRTCQLIEAATEEVVLVVGDESLLTEELVETLTDVDDDIDLIVGTLTEPLRDEVEAAVPRATTFVSGLEWLRDDEATDHETAVGRLLLIDRSSILVSSILLDGNREQAVYGEGFGNGFVVIARRLMAHGLIPGQDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZD0</accession>
    <name>V6DZD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14019" checksum="70FEF3ABE5C5DD32" modified="2014-02-19" version="1">MSINDLSTGTASYSRAAGASVVFTAARLSATYNRVTGTSRTSPFLTEPRSTTERRLLTHLDSYCGEPPSVTAVSTDSAHQTLLRRPARESSILTTDPTGRSATRSRASSSAYSTTWYVSLRGWARTVVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZD5</accession>
    <name>V6DZD5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_02749</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078080.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77089at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="21"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="403" mass="45365" checksum="408CE1D3F1906DEF" modified="2014-02-19" version="1">MYLCQVAPYVTYPPRMGGDHRTHGLVKEFPKEGHTVHRYCQGGSPAMYKSLDLRRHVRIAEDYDEYRHLNPLHEATKAPMLLGYPNLLAHRSLRIANDGLDEMFERADVVLAREPWQMPYVLDHVPEDTPTVFSSHNVEIERFGDISQPAFAECVEREVDRLEQRSVEETDAIVCTSENDADIYRKRYDPEGPILVAPNGTYEDRLRDHRPGSDAAKRVRREYGIDTDATVALFMGSNYRPNVEAAEAVVDIARELVDADIDAQFLIMGSVGNALDRSSLPENLVTTGYVEDEFEAHFDAADIALNPMLSGGGTNIKLIDYFARSLLVISTPFGARGLQATAGEELLVAELDKFPEKIRSLSQSPDRQHRMGDAGRQLAAEKYTWEASSRMLLKFVTENFGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZD6</accession>
    <name>V6DZD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_10993</name>
        <name evidence="2" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078117.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121637at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7999" checksum="C438AF08A0C7E392" modified="2014-02-19" version="1">MTRSSLDGEWEGQPDDPAGDDLGYDLDEWERIRAAGVDSDKFLYLPGDDDLLREEAFVVVAPADVADLVDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZD9</accession>
    <name>V6DZD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">dTDP-glucose 4-6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rfbB</name>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8783" checksum="E5A6D2A6DF35076E" modified="2014-02-19" version="1">MRAITRIHRITVSVAYIGFGTLSRDKYLLIEELAELVVDVVETDSDIVYEDLPVEDPQVRQPDISRAKERLDRTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZE4</accession>
    <name>V6DZE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family protein</fullName>
            <ecNumber evidence="2">2.4.1.250</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OCC_01439</name>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.250" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="201"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="373" mass="41239" checksum="A0E48D0220259293" modified="2014-02-19" version="1">MSKSVTYAFGGDLGGAGIGRIAGHAVGGVQRSSLRGKAISYTLSDEQLTEVTQTHSGGSILRKIPNYHVKDVLFNRLTARKIEGSDLFHGWNNMCLHSLRTAKSVGAKTVVERASTHPTVQRSLVQQERERFGVDEPSRNERLHERAVTELTEADAVFVPSEFVYESFLDEGFNEKQLYQIPFGVDHEQFAPPENYIRSEHPFSALFVGSISLRKGIQYLLPAWKQADVDGTLRIAGEVTKPAEPIVDQYREDDSIEFLGWVDNPSEEFRRASTFVFPSVEEGSALVSYEAMASGLPAVVTSNVGSLVRDGEDGIVVDVGDINALTDAIERLGSSPETRERMGKSARKRVEGYTWERYGDSVVSAYESILQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZE5</accession>
    <name>V6DZE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Family 2 glycosyl transferase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_10938</name>
        <name evidence="3" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="143"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="460" mass="49748" checksum="206A9254BE06944E" modified="2014-02-19" version="1">MYRGATVAVVVPAYNEAGFVGEVIETVPRFVDRVYVVDDCSTDDTWAEIRETLSGFEGSERPGGLLRPVVDRAETVSDGSGAITDGSGTITDGSGAITDGSEAVAGGSGPIDDGPRPVPDGLKPAWRDRIVARDARSGTPLPDRHIVALRHRENTGVGGAIKTGYRNAAGDAAGVDVVAVMNGDGQMDPTILDRIIDPVVNGDSHYAKGNRLRHTEYRRDMSVWRTFGNFLLTGLTRIASGYWGMTDPQNGYTAISREALKRVEFESLYEDYGFCNHLLVRLNRQGLRIADVPCERCTATRRATSGTARSSRRSRCCCCGATSDGCSTPTEEGSATRRPPHSSSGWDRSSSGSRLGWVRSSRSLRRRRPRAESWRFSVSSRSSPASRPSDGGTPTWRSESTRTHRRXXXXXXXPTPLCRLRLPRLDLAGTARRAELDSMSRIAIADPTSATGSSIGSARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZE9</accession>
    <name>V6DZE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C477_09104</name>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="217" mass="23943" checksum="DA0B9783D2A33D86" modified="2014-02-19" version="1">MLKRLYNTLIRERLPRKIGVFNGVPVRQPRLLDRTDVQPDYEDALITAIRQCISEGDTVVVVGGGWGVGTVVAAENAGESGWVITFEASKEQTEHVRETIRINQVESRTDVEHAVVGPDIHVYGEVMGARQLSPGDLPECDVLVLDCEGAEMDILQHTQQVGKEIIVETHPMYDAPAEKVEELLTEGGFVVKSVRHEQSTYGELPVLTAVREESANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZF0</accession>
    <name>V6DZF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6279" checksum="247A731847067DE5" modified="2014-02-19" version="1">MDRFDRCDNGRFDRTLPGLFDHLFGTFDHLSETFDHRFAGIVARGQSAFDRGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZF4</accession>
    <name>V6DZF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ISH9-type transposase ISHwa3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_00307</name>
        <name evidence="1" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6427" checksum="B46C41328D6C4281" modified="2014-02-19" version="1">MLKRVTGDGGESAAPEGGGGFADYALVSLHCLRIYLDTSYRMTIDLLKEMPPNNRGDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZF6</accession>
    <name>V6DZF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_14531</name>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="11612" checksum="8F468D5C1B7FEE45" modified="2014-02-19" version="1">MRSRFDPWTALIGNRLYNVYSFSKRENTGIIYFRGADSFGMDFSIQQAVLLILGGLIPAVVFIADRSEVFVAVSLVNVLLIWVSLRIATGGSVPGISGDDTEPDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZF9</accession>
    <name>V6DZF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide sugar dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HLRTI_12820</name>
        <name evidence="2" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8114" checksum="FC52FB4EF3BD7797" modified="2014-02-19" version="1">MIKYANNAFLASNISIANDLGNICKEYSVDMYEVADARGLDSQIARLFLDSSLDWGGSCFPQGRRRDHRCRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZG2</accession>
    <name>V6DZG2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="11575" checksum="C4FCDE30835A1AA4" modified="2014-02-19" version="1">MADRARGGRPGVAVSVPFSALASRPRQLCLRNARQSYGRDTRHGSVSRLFARDDSRQAPRRPRRRERPRVDDRSRGRVDHRIARFGRLAGRCRRRCLRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZG5</accession>
    <name>V6DZG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="9397" checksum="19DC424745CA57BC" modified="2014-02-19" version="1">MDRTVAIRLTDRLADRVAAVPRHDDELVDDFAGGLEHLFEQRAVPDRQERFRSAVRQRSHPGPAAGREHDSVHVRHRRRAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZG8</accession>
    <name>V6DZG8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_13377</name>
        <name evidence="1" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078141.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100747at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="202" mass="22256" checksum="A52E67650BD44B55" modified="2014-02-19" version="1">MTVLPDAVRGADSVLISGPPMSGKYDLFNRLLAAWSDGPVVISTGRTAEKVRGDYEGLTGKAGDDVVVIDCVTHEQGDKREDTPTTKYVASAGNLTDIGIKFTDVVESSAGRERAVGIYSLSQLLMYWDPERIYQFTRVMTSQTSGEGWPFVGVLGSTAHDEQVVHTLHEPFDTVVETRVDDDAREFRVRDRVGQPSDWQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZH0</accession>
    <name>V6DZH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C468_06188</name>
        <name evidence="4" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulator TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078112.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72347at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021586">
        <property type="entry name" value="Tscrpt_reg_TrmB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11495">
        <property type="entry name" value="Regulator_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="2">
        <location>
            <begin position="14"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Regulator_TrmB" evidence="3">
        <location>
            <begin position="120"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="30438" checksum="7C529695C5AF0083" modified="2014-02-19" version="1">MTDQPARREAVELLQQLGLKEYEARCFVALSRLPSATAKEISERSGVPRTRVYNAARVLESKGLVEARHASPKRYRAIAVDEATDLLRDEYQSLTDSLREDLRSIDPVESDEGSDPHQTVWTLSNAPAITNRMRRLVEGAEDEVVLLVGREGEVAEPLRRTLRDAHGRGVSVVVGATTDALRRSFEDCRDVDTISLRDTWIEQSAAAGTDAEIGRVLLVDRETVLITTVHADGRGERREEAVFCQGSANGVATIVRRAVLALLPADDVAAVAQQSGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZH5</accession>
    <name>V6DZH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_09716</name>
        <name evidence="1" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11650" checksum="9C346FA562809E4A" modified="2014-02-19" version="1">MSYEAVLFDLDNTLYPYAPCNEAGKRAALDALRERGYELDRDAFDDLYAVGRREAKRETRTTAASHDRHVYFKRGLYRHAGEPDVAGALAAGDATGTVPRRDGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZH6</accession>
    <name>V6DZH6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alginate_lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_11018</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alginate_lyase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="131" mass="15018" checksum="AD3FD769F5EE88E7" modified="2014-02-19" version="1">MKHEIGRVDGLEYSVYGLKALTLTAEIARHYGVDLYGYRLPGDDESALCRAFEGHRPYVLDADEWEWGTGENGYTDADRTAAGSVYELAHSRWSRSEFRRVVESMGRPLYERRILGWTTLTHANRFELDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZH8</accession>
    <name>V6DZH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6484" checksum="442035B4FC925C0F" modified="2014-02-19" version="1">MNATRGDRAWFPCHLTSPFRPLIPALFRFLGSIPPFAVAAPTDGAVVPRRPGRRLARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZI1</accession>
    <name>V6DZI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4905" checksum="BEFFF43E785EBFBD" modified="2014-02-19" version="1">MTHYERVRELPGLALSEGEVRLVVARAIRHRTGDVRPHDRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZJ9</accession>
    <name>V6DZJ9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="8">SHMT</shortName>
            <shortName evidence="8">Serine methylase</shortName>
            <ecNumber evidence="8">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">glyA</name>
        <name evidence="11" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078160.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="22518at2157"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="10">
        <location>
            <begin position="7"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="123"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="353"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8 9">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK40790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="415" mass="44453" checksum="0234091D984BA2E3" modified="2014-02-19" version="1">MDHEHVREVDPAVADALAGERDRQEQTLAMIASENHVSEAVLEAQGSVLTNKYAEGYPGSRYYAGCEYADEVEELAVERAKELWGADHVNVQPHSGTQANQAVYYSVLEPGDKILSLELNHGGHLSHGHPANFTGQLYDVEQYEVDTETGYIDYEGLREAAEEFEPDIVVSGYSAYPRTVEWERIQAAADAVDAYHLADIAHITGLVAAGVHPSPVGVADFVTGSTHKTIRAGRGGIVMCDEEFADDVDAAVFPGGQGGPLMHNIAGKAVGFKEALAPEFEAYAQQVVDNAEVLAETLQGHGLSLVSGGTDNHLILADLRDSHPDLSGGEAEDALAAANVVLNGNTVPGETRSPFDPSGIRAGTAGLTTRGFDEDAIEEVGDLIYRVVDDVDSEDVIYEVGERVVELCEAHPLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPJ2</accession>
    <name>V6DPJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076006.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="18193" checksum="E7E026B8157F9D6B" modified="2014-02-19" version="1">MSHTKTLTAREAYHDSLQFFEEIKQNIGHGIINDKSTVSFTEKLEPEEDFQIRLKATHATLAMFVKRYRAAEFTFHTERAPIDGYPETARQNNPLVTHYAEFTVDFTPYGTIFGGHSDDNGGNATKQTCSSHRDGNALTGPTGPATPDTPTGPMAEQTSAVQSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPJ3</accession>
    <name>V6DPJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HLRTI_11965</name>
        <name evidence="1" type="ORF">BN903_281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="12347" checksum="F2E3342688E21593" modified="2014-02-19" version="1">MPTDGFTTAQRRRIQRDLGRWKLELEMPNRFSDADLEAYLQELQTLDDETLACWWTDNVGEWIASRGDLDIPPDADVDEWLDAQFDTLVRGDTTAYGFVVDVLLPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPJ7</accession>
    <name>V6DPJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076011.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="131963at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="263" mass="29181" checksum="8042671A59166C1B" modified="2014-02-19" version="1">MSNDNSRFTSDRRPLDRATWSETEDWEAGVAENLDIDSGDLVAQRLTTIGETPDTVVDNFETGDLSRYDTASGGNFSVTPNQVINGAYSLEADFEYDTPNQKNIFSMSGLANYPKKGDTFSFWYRANSSYGEKPRVFFNYIDSDNYYMIGINRSNGGPNYYKVRVFRIGDDGSEIICTTGGNGSWKGNANTWYEFEIVWATDDVFELYIKDIDGVVEASASGSDSSPLPPAEGIGFNASGDSAYGAGTTKIWFDNFQIKNRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPL1</accession>
    <name>V6DPL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6616" checksum="42ED66ACD95CAD99" modified="2014-02-19" version="1">MTTNTSNNGESSDAEQQDAGGFAELTAMEEEMEAEKREALEEIAKFSVSPPSDLPVSRPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPL3</accession>
    <name>V6DPL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5192" checksum="EE7E44964DBF5E7E" modified="2014-02-19" version="1">METVIRTQVLDGNLHPLFVWFTWTFCVVSRLKFSLNSVSSAADFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPL5</accession>
    <name>V6DPL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6779" checksum="3205AE4EE2CB8A06" modified="2014-02-19" version="1">MVAVRFHEVCRVACYVAHVCWFLVRSSERGLSGGCFSPFSLSSPPLGTYKTSLRGALFSPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPL8</accession>
    <name>V6DPL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_364</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076016.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="20482" checksum="C788A9BE8B146FBD" modified="2014-02-19" version="1">MLADRDHVTLEPQGYDGSETFPILNGRRIDELSILFNIPVEELTSKYMLRLEELRADKTFENDYDGYDVFHLKCQKAVESAINTHDPRVKNARADDVVAENVGHMYTEGTTDWSELALTWLTEWLRLYNSNLRYNTNDLAEGIFEAIRNAAENEYITRDEIDHLVDVALSEEPTDHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPL9</accession>
    <name>V6DPL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7536" checksum="0415127CF09B2A20" modified="2014-02-19" version="1">MTLQTNHETSNSPECNRCDHGFSKEDKACEVLSGRSGSRLGTAVVCTSCAKKAGVDVGAFARPAPEVLPELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPM2</accession>
    <name>V6DPM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="11853" checksum="E40D0864CD2902DC" modified="2014-02-19" version="1">MTPPPPTGPYADALADADLRFAFSRIGSLIREGVYKQFPENCPECGGGVLVSHGGDRVRCWANRGVDDCGWNETRCHDCGVTPNGWFTYIQDGDLLNPPCVQHRGYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPM4</accession>
    <name>V6DPM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="12802" checksum="FFEB242E0B215B76" modified="2014-02-19" version="1">MVVDALLFESLLCGIGLDIFDELAVEFLVVDASKWAVGLVIASVVDDSLAVRTLRSRWGVPRRSRTVRIDVWWERQISVSSTIIGRYKLSNRVARRGDSTESSMDRLSRIEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPM6</accession>
    <name>V6DPM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="5982" checksum="B3998FD9E7DDD794" modified="2014-02-19" version="1">MEVHIDGLGIGSEFLALVIKRDGPIGESLGIEVGVDGRDGEDGVGIVNIQAVAFAEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPM8</accession>
    <name>V6DPM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8255" checksum="895B9DABC95E07DC" modified="2014-02-19" version="1">MFFGFSEQAVEELREGIGLAGVKVNNVGFTTIEQETQSPSVTIQGLDTKNSRLLATTLSEAGLGGLVESDPIVIIESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPN1</accession>
    <name>V6DPN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14797" checksum="6A827130BF13F9D0" modified="2014-02-19" version="1">MSQSELIAAPMSNDETVTIRVWRGRHRDFDRDPDETHEVSCHDGERWSAETVQIDGTNSCGWLAFDLVDLPEDMETATLFVHENNSGHEHPLNTRAVERGLVFDGRPYKPGIDPPCFLLDGEVVAHVARGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR0</accession>
    <name>V6DTR0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Catalase-peroxidase</fullName>
            <shortName evidence="8">CP</shortName>
            <ecNumber evidence="8 9">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">katG</name>
        <name evidence="12" type="ORF">BN903_119</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer or homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="8 9"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077170.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2839at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8 9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEROXIDASE_4" evidence="11">
        <location>
            <begin position="111"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="PEROXIDASE_4" evidence="11">
        <location>
            <begin position="454"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-77)" evidence="8">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK39567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="711" mass="78769" checksum="423E983570ECF2EF" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR2</accession>
    <name>V6DTR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_05714</name>
        <name evidence="3" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077163.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130239at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="8126" checksum="7D44E5BE388B2D98" modified="2014-02-19" version="1">MPDPNPETDAGPIPETRPTADVGPAPDGESNPRDRPALLAATPDADTVFERLRTLALLAGFLGLLLTLIAVELLVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR3</accession>
    <name>V6DTR3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08259</name>
        <name evidence="2" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077173.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124564at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025707">
        <property type="entry name" value="DNA_bp_PD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016702">
        <property type="entry name" value="DNA_bp_PD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="139" mass="15643" checksum="5337F74EC38D3ECF" modified="2014-02-19" version="1">MYHREVEPTAEYVARFETGADWREEIESLAREEDVEAGWFTALGAVQDADVWFYDQEDTEYRSVTFDEPLEVAACVGNVSLLEGDVFAHTHVVLSRPSGQALAGHLDSATVWAGECHLRAFAEPLERSHDEATDLDLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR4</accession>
    <name>V6DTR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase</fullName>
            <ecNumber evidence="2">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_13642</name>
        <name evidence="2" type="ORF">BN903_229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076667.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100703at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="197" mass="21106" checksum="5284511262302E57" modified="2014-02-19" version="1">MKVVVVDNFDSFTYNLVEYVSDQRIDGEPVGVEVFKNTASLDAIEGADPDAVIISPGPGHPKNDRDVGVTMPVLRDLSRRVPTLGVCLGLEAAVYEYGGTVGHAPEPVHGKAFAVDHDGEGVFRGLDQGFRAGRYHSLAATEVPDAFEVTATTDHDGESIVMGIRGRDHPIEAVQFHPESVLTGSGHDLIRNFLTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR6</accession>
    <name>V6DTR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_00604</name>
        <name evidence="2" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="298" mass="33301" checksum="5025506229900E4F" modified="2014-02-19" version="1">MSELRQEAEAIAEQFSDHTDVDPDDVEERLATLVDEYRVPLDEARRSVTNSYLEDAGMERDELGRGGSEEVLVNDIDEDEQWVDLRVELVDLWEPRSDSISQVGLLGDESGTIKFVAFETSDLPELTEGQAYELTNVVTDEYEGSYSVKLNRTTGITEIDEEIEVGDNADTVEGALVDIQSGSGLIKRCPEEDCTRVLQNGRCSEHGQVEGEFDLRIKGVLDDGETVTEVIFDREATEDLTGMTLEEAKNMAMDALDTTVVAEEMGEDVLGRYYRVTGPTFGRYVLVDEMEDPGRCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR8</accession>
    <name>V6DTR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_00859</name>
        <name evidence="3" type="ORF">BN903_146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077190.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102375at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="158" mass="16614" checksum="0F4F551EA063EC8A" modified="2014-02-19" version="1">MFSLDEDDEGEISVGESSDAERKMTPDIPEAPSVKTFDDAGDFEGASDVDSGTLRAFVVAVIYANAAVLLVALGPMVWFFEGWSRLGPALIVAGLLAGVRTYQTYRSWSRARDGDADSGESGSGEKADVDSDADPDDETATADDDRTGADPEPASPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTR9</accession>
    <name>V6DTR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3863" checksum="C235B62584A7A112" modified="2014-02-19" version="1">MRWRVPARPHRGRGASREGVAGSRSGAEGASDEVGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT0</accession>
    <name>V6DTT0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6913" checksum="D2CA61299F135BCD" modified="2014-02-19" version="1">MAIRICAWYRTEIKAPPNPGRVHGRRRADGADGADRERRIRPSKTPGIGADRDRGSTEVTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT1</accession>
    <name>V6DTT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_13407</name>
        <name evidence="1" type="ORF">BN903_249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076781.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113344at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10971" checksum="16BDB8E0BBC01494" modified="2014-02-19" version="1">MRVLDDGAWISVNDDRKVRVSELWRLDAPDLCECALTDLVVENFQAVGVDGGAVEARVYGQCIACGETGITGWIPVGRLQDGSFAEIDRDAVRCPTRDSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT2</accession>
    <name>V6DTT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4303" checksum="11587FE4F11B1C74" modified="2014-02-19" version="1">MSFADAVDGGWLALVGVGGGYALAVGLVFLLFFVAPYLAVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT3</accession>
    <name>V6DTT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08269</name>
        <name evidence="2" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077177.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118444at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="11452" checksum="DE071DCD468796CB" modified="2014-02-19" version="1">MLVVHAAFPIDPDRIDEALDHAETLVAESNREDGVIDYRAARDVEDGAMLRFFERYEDAEAFESHSRTDHFEAFEAALPDLLAGEPEVWQFEVESAAQLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT4</accession>
    <name>V6DTT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_08125</name>
        <name evidence="1" type="ORF">BN903_293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076384.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="60" mass="6112" checksum="DE7FC36A991ED8EA" modified="2014-02-19" version="1">MDVLSRYTLAFVLMALSLPAISYGASAGIAIAWGVGLAMLFVGGLVPPAMRFAAADPDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT5</accession>
    <name>V6DTT5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="5">4.2.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C471_13983</name>
        <name evidence="12" type="ORF">BN903_254</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the LeuD family. LeuD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076694.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86621at2157"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="14"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK38960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="23536" checksum="71790D55E4D7A47A" modified="2014-02-19" version="1">MSSPEFSDGEAPAEKVTEVSGTGIPVRGNDIDTDQIIPARFMKVVTFDGLGQFSFFDQRFDDEDNEKDHSFNEERYRGANVLVVNANFGCGSSREHAPQALMRWGIDAVVGESFAEIFAGNCLALGVPTVTADQDDIEALQDYVEANPDAEIDIDVAAETITYGDTVIDATVHDAQRKALVEGVWDTTALMGANEGAVRETARSLPYVPAEHVSGDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT7</accession>
    <name>V6DTT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="12704" checksum="D02CB5B27114AA90" modified="2014-02-19" version="1">MFQLLVAGVEAVERVDVRGDRRGPLVDVAVLRLAPLGHAGVAVRVDQPGRDVVARDVDHGRFRGRLAVLDGDDLAVVDDDGGVDRSPLRCRVDGPADKRVHGTGFCGAVLNGQGCGRSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT8</accession>
    <name>V6DTT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="5674" checksum="F6270B421DCEBA8D" modified="2014-02-19" version="1">MTESEPERCSRPSTVDILFPLVFSSLVGGLFFGVFGAAVGGALGATIGGLVGNSDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTT9</accession>
    <name>V6DTT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_12776</name>
        <name evidence="3" type="ORF">BN903_133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077180.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63636at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="41"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="260" mass="28204" checksum="23E78477097A75B9" modified="2014-02-19" version="1">MSDSAHATNGSAAAVAERDEDESGAETSGDRDEPYTFDDLSVVMGTYNEEEAIGTVLEDIEEVTDGKAEVVCVDGSSDRTAEIAREHGATVIEQEPQGYGVAVQEAILTPDRPVVVTTDCDDTYPMEALPEFLAEINDGADVVSGDRLYHGAAAMPAFNRFGNHAFAALASLLMGERVHDTTTGMRAYRRDVVEEIGWTENTGLSAELLIRPLMRGYDVRERPIRYAERLGETKLDPIGGGAAIAKSIVTVCLEERLRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU0</accession>
    <name>V6DTU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_03244</name>
        <name evidence="3" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077215.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="310"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="506" mass="56313" checksum="6AF554E4A8DBAEBB" modified="2014-02-19" version="1">MSGHPRGSASDQDLQAVLDRMADGFFALDADWAVAYANEQGRRILRSAMSDDAVGPGESVEGRNLWESIPGSTETAFYEEYHRAMETQEPVSFDSYYEPLDTWFEARVFPSESGLSVYLRDVTEQRELERRQRESLHAIQRLYAVSSDHDRSFEEKVEAILTLGCEYLDVPNGFLTRIEDGTQHVEVSHADHPLLQPGEACPLDEAYCKRTIERDHLLTVVNASEEGWADDPAYETFGLETYIGGRVEVDGEQYGTLCFAATTPRGEPFTDTQQTFVELLTRWVSYELERQRAATRIERERDRLDEFASVVSHDLRNPLTAARGRIDLLAGESDSDHVDAVQRSLSRMETLIEDLLTLAREGNDVDDPEPVDLAALAADAWETTDDRDGTLRVAADEFGILADEARLRQLLENLFRNSVDHGGEAVTITVGSMPGGSGFYVADDGEGIPESERDQVFETGYTTATDGTGFGLNIVEEIANAHGWEVRVVESEEGGARFEFTGVKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU3</accession>
    <name>V6DTU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_03269</name>
        <name evidence="1" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3888" checksum="88066BEF3A67012C" modified="2014-02-19" version="1">MGDDACDREFCPACDLAVACTDEECPECGAPIGPRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU5</accession>
    <name>V6DTU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C443_03289</name>
        <name evidence="2" type="ORF">BN903_308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0175 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076395.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118704at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005368">
        <property type="entry name" value="UPF0175"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03683">
        <property type="entry name" value="UPF0175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9280" checksum="6A7AACC7740AFF31" modified="2014-02-19" version="1">MATIEIDDDVYEALQLPERERSPALKRELAVSLYAQDVLSFGKARALAGLSKREFQDLLGEREIPRHYGKRELEEDLGYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU6</accession>
    <name>V6DTU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transporter inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_04528</name>
        <name evidence="6" type="ORF">BN903_264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076700.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68860at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="266" mass="27858" checksum="2015926185F519F5" modified="2014-02-19" version="1">MATDARTEPRTIGPVAVPSADRFHPLLGLVVPAALVVGWHVVVATGVIAAYQLPTPLRVAETLYGMAASGELLGHVAITVQRVFLGVGLGIAVGTVFGTATGLSRTASDLLDPLLQSLKNIPSLAWVPLFLLWFGIGESAKVLLIAVGAFFPVYLNLSTGIAAVDEELLEVAEVYDLGRVESLRRVVFPAALPSLLVGIRGGVGLAWMFVVAAELIAASQGIGFLLSDGRTLARPDIIVGSILLFAFLGNCSDVAVKEVRDRVVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU7</accession>
    <name>V6DTU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077218.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110213at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="141" mass="15387" checksum="DFBE6C1B2B4B8841" modified="2014-02-19" version="1">MQKSRRDVLKGSAGTTLLTGLAGCSASDRIPPSLNPLGDAPAIKFRFDGFAGQRYEITHTGGDTVDATRVRVQYTEVDSGEQKYIKWNLFGKVNSELDISPDKTLTTPTGVEGGTKIRVIWVPQNGDDNRTIGVYEVQKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU8</accession>
    <name>V6DTU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4281" checksum="A471C60AE1931D3E" modified="2014-02-19" version="1">MSGSSSDPESARVLFLSDRTPPLTPTGGLGGFIRSHEHPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTU9</accession>
    <name>V6DTU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_13297</name>
        <name evidence="1" type="ORF">BN903_269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="33515" checksum="E0CDB6E07C2E9991" modified="2014-02-19" version="1">MPTPDADPIPPGASVLTPVSYVNYLRRGVSSHGDLCAVFLFNSDEQAEAFRNAYADPETPDGIEKWRVLSAPSSDAVSDVFSDSSTDIVYCGLPIDDGAVVSVDGRVEISSLGAPNELNSPAVVVLEGTRDVKTGLGLINAGALGTVLFDGNLPSESVRQLIGLLSAGGSISVATALAIRDEGTQARFIGDPGTLASKNRGFPLQLLSLRSLDTNSLAVDRWSFTSIKAMLGMECSTIVDSLDRRRRLAGTRHREPEPIAVSDALNIHSGSEVQICLNGDLVLKSDDLTAEDIEESATKALSEVSETESHADSQCRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV0</accession>
    <name>V6DTV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5017" checksum="BC877030CE40C2E6" modified="2014-02-19" version="1">MTSHINVDYPSAAVLPTPTPFSPPTTDVVVSDVDRAISWCRATLSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV2</accession>
    <name>V6DTV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_12961</name>
        <name evidence="1" type="ORF">BN903_149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077193.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129932at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9634" checksum="AB137C6F14BFCAA5" modified="2014-02-19" version="1">MSTTDAVTADDGTADRWAAVRDLPPSAKLVAKVLDYNDTLTQSELAEETLLPPRTVRYALSRLEDEGVVDSRFSFTDARKRLYSLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV3</accession>
    <name>V6DTV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_13212</name>
        <name evidence="1" type="ORF">BN903_274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076709.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89147at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="19113" checksum="6CE624107FE1F4E4" modified="2014-02-19" version="1">MTPLEPTDDLLESLYVVNKVAKQFADEATAAYERGDVTESNVRSARKDALYRLKTAVLSRIVAYDAERVTGEYHAINGDVWLFLTVGDWHFHQPPHAIGGDLTDDIEISNSRAEPLDAPYVRDAGVERSDRTLDEALAHLADAGVNANDHLARPTVTGEHDRIVDVRWSFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV4</accession>
    <name>V6DTV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077220.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20105" checksum="4ECD71D86C1D4209" modified="2014-02-19" version="1">MSTENTPTTSDAPEAPVGADEDDVGADVIASLQAEQRRLSNELDSLREENEQLRSELEATTNLARKAHERIHDLESTQSSVSDATELEIALQQSDTVIEERYSVAEQRALVMAHYTASCGGPRGVRISDDTFQRSVEHELEESLAWAQLDRAADALASMAGDAVEHVSDGDGNRLVVNDDSVLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV6</accession>
    <name>V6DTV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="709" mass="78467" checksum="D81C1D68B2BDA32B" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV8</accession>
    <name>V6DTV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FeS assembly ATPase SufC</fullName>
            <ecNumber evidence="6">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C470_07941</name>
        <name evidence="6" type="ORF">BN903_143</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077188.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44302at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="307" mass="33833" checksum="E99758814EF6E88A" modified="2014-02-19" version="1">MATLEINDLHARVAEEGGERILLGVDLTVESGDIHALMGPNGSGKSTLAKVIAGHPAYEVTGGEILLHLSEEDVADIDADLDDEDYHWELLDLEPNERAALGIFLGFQYPAEIEGVTMTNFLRQALNAKADEREELFEDEDEAEAEADEEDDEGYDTSPMEGAADEGEIGVAEFQEILSEKMELLDMDEKFMQRYLNAGFSGGEKKQNEVLQAAMLEPSVAVLDEIDSGLDIDRLEDVSKGINALRDEQGTGILQITHYQRVLDYVEPDHVHVMLDGEVVKSGGADLAEKLEDEGYDWVREEAFEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTV9</accession>
    <name>V6DTV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxal-5'-phosphate-dependent protein subunit beta</fullName>
            <ecNumber evidence="3">2.5.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_03234</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077214.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47519at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="2">
        <location>
            <begin position="14"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="326" mass="35062" checksum="A9CA089F07A56D18" modified="2014-02-19" version="1">MTTHAEPLSSVVETIGETPLVRVHDSPDAVPVYAKLESFNPGASIKDRIGKYMLERMLERGDVGEGGTVIEPTAGNTGIGIAVAAGQLGLNAIFVVPERFSVEKQQLMRALGAEVVNTPSKDGMELAIERAHEIAEELDDAVVPQQFSNPLNAEAHYETTAPEIDEALDGEVGAVVAGCGTAGTLMGVARYFREADADTHVTAVEPAGSAYREFFGEDVEHGEYKTEGIGTHDIDTNELFDPDLVDEIQAIDDRDVHEEMGRLAAEEGQLVASSAAANSLAAKRVARDIRDGEIDAPHETVVTVFCDSSERYLSKGVYRSFEEWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW0</accession>
    <name>V6DTW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04673</name>
        <name evidence="2" type="ORF">BN903_279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076714.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="56787at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="320" mass="34697" checksum="C27C616FE3A0466A" modified="2014-02-19" version="1">MSQFDRSGGVASDGDRADRIDGADAAAATPRTESRIPPAEVFAVLGNETRVEVLHALLELGGDESPVSFTDLFERVDATDSANFSYHLDQLTGHFVRRREEGYEFRAPGRKVVSSIFTGTLTERAQLGFFPAEGSCHACGGDLHAWYVDDTLSIGCTDCGAIQVSYPFPAGALDGRSTDDLLEAFHHYVRHHYCLAADGVCPECTGTVETDLVRTPDEEGQAVAVEHACQRCSYDLRSTVGLLLLDDPDVLRFHADRGVDLSSVPFWEFDWCVSDAATTVVSEDPLRVRLTVGCAGDEMRVGVDESGTVVETDGPERDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW1</accession>
    <name>V6DTW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="11122" checksum="F2691BAC5E324A40" modified="2014-02-19" version="1">MFPDDRPTRHAVRLGGLDVPLVDRFEYGCARNPEFAPHRRRPKHHRRGQHLFDGREEAGRRRQTRQVGRAGHGGRHEELAPVEPQQRVRLREHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW2</accession>
    <name>V6DTW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077227.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9094" checksum="5376986AF874C327" modified="2014-02-19" version="1">MFSDLVTDEILLGIAIGLVFDEVGRKLVLSRVRTILGAEECADVDDDSDSRDDTATRGDSTSAHTDTADYFDPTVAGGADKVRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW3</accession>
    <name>V6DTW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_14464</name>
        <name evidence="3" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="295" mass="31026" checksum="A2365160F6718870" modified="2014-02-19" version="1">MSNADRRTQFWALYLTRFAEGFGFITLITLLGTYINTLDPQATTVLGVTVSAGFIIGMYTTGFTLAQTVAVVPLAWAGDRFDKRTVLLGVLAVGAGVYALFPLVDSSGSFILVRALQGLVVTGAGLMTLSLVGQIADVGTRADKIGKANAASFAASILGSLSAGGIYDAVGFGPIFTIIALLMVAAWVVTWLFLDDDDTRIEGFPFSDLAVNRRILTMTSFRAQYAFAVTMVRTWVPIYASTEMATGGLGITGIAIGVTVTAEKATNMVGQLFTGRLSDAYGRSLFVFAGGGATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW5</accession>
    <name>V6DTW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4905" checksum="EB31F3B06EE27113" modified="2014-02-19" version="1">MVRHLRLFKKTDISEYTIRISIPTPADDYMRKVILRVLLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW7</accession>
    <name>V6DTW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4631" checksum="87933B1D2CFE0856" modified="2014-02-19" version="1">MSMWYADICSSASDIILTPSTAENFSETGSTHVDRIPPRQSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW8</accession>
    <name>V6DTW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Huta_1074</name>
        <name evidence="2" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="68"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="234" mass="26945" checksum="063EE13550BAF50A" modified="2014-02-19" version="1">MLTVHALRIELAKSYRVAVDLLSEMPGVLEEIGLTRLPHYTVLRTWFERIPTKTWRAFLGASAEKCTGHAAIDSTGFDRDQPSRHYANRTNYRVRALKVTALVDVETLYITDIHSTTSKKHDAKIGPQVARRNAGDLRSLAADRGYDSKAFRDELRENGIRPLIKHRIMNPLDHAHNARMDGDRYHQRSMSEAVFSSIKRTLGSAVRARSWWLEFREMLLKATVYNLRRSVRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTW9</accession>
    <name>V6DTW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="11086" checksum="72C0B7B6D187A90A" modified="2014-02-19" version="1">MINRYRISRRDSQTDPRPRVYKVREGEWKIGAYLAIDGRLVLPHRAERPSLRIHWLCRNPQQLIVSRLQSLNTGNSRIAQYTLLTAFSQPLCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU31</accession>
    <name>V6DU31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6608" checksum="FE0BF69810BCB0BC" modified="2014-02-19" version="1">MSLDAYRARRQIQRVPSKIGKIFIMFVYNYVSMERHAIGERLLNVSDPEIRTNHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU32</accession>
    <name>V6DU32_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4145 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nmag_3626</name>
        <name evidence="2" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025285">
        <property type="entry name" value="DUF4145"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13643">
        <property type="entry name" value="DUF4145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4145" evidence="1">
        <location>
            <begin position="115"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="27454" checksum="3E69C058C9DD5D24" modified="2014-02-19" version="1">MRGGIRIEGACQSHFTDILGYCLFIRRDIYDKMDDNYVAPKYKEDGFNCPHCGAYAQIMWSTMAYNQRKIEGDISKCNRCGNYSLWMNRKLCYPRTPSASKAHEHMPDDITGEYNEARNVVDESPRAAAALLRLALQKLLENHLDTPGDGIHHDIGHLVDENEIRPRVQKMLDGVRITGNNSVHPGEMDMEDDRDTALALFKLLNYVVDETIGRDKEVEEFWDTLPEQEKEWVEDRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU33</accession>
    <name>V6DU33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5326" checksum="94382AABF5795FC4" modified="2014-02-19" version="1">MTASRSSWRSNQSMTDELFAYCPEHDRLFENESLMARYQAKAGGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU35</accession>
    <name>V6DU35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="7645" checksum="5C44E27F4C80DE77" modified="2014-02-19" version="1">MLSLRQHPRTIPFDRYATSGYAVSIFEAVSTFKALPLGSTRSISLPAISRLRLPKPQSLGSTRSVSTGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU36</accession>
    <name>V6DU36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Na+-dependent transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Natoc_4239</name>
        <name evidence="3" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076808.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96924at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="282" mass="29215" checksum="A76D2535C1B47E32" modified="2014-02-19" version="1">MIADVTDTIVNLTTTVFVLSTMLAVGLDLSIGQLREAMGRRRLMTKSLLVNLIVIPALAYLLVYSIPMVPSYAAGVVLLAVSPGAPFGPKLAEISDSDLAFASGLMAILAVVSVVTIPVSLALLLPGNVSVDPVAIGRLVFGVQLVPLLAGFVVTYRSSPAADALYSPVQRLSNYSFILLIVVLLTVYIDDMAALVGTGALFVSSVIVAGSLAVGYVFGGPARSTREVLATTTAARNAAVALFIATAGFSDPGVLTVVLAFSFLGVVASALLATIWRRRTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU38</accession>
    <name>V6DU38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4280" checksum="E8086BA20DC744AC" modified="2014-02-19" version="1">MSVYVGTNCRRLILAVSVAYVMFAEYSLYHPTNAPNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU39</accession>
    <name>V6DU39_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L44e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rpl44e</name>
        <name evidence="4" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004595867.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38950144"/>
    <dbReference type="GeneID" id="55718058"/>
    <dbReference type="GeneID" id="65212839"/>
    <dbReference type="OrthoDB" id="106603at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01476">
        <property type="entry name" value="Ribosomal_L44e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_L44e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="10655" checksum="CB447772F0D26610" modified="2014-02-19" version="1">MEMPRRFNTYCPHCDSHHEHEVEKVRSGRATGMKRDARQRRRALATIGNAGGYSKVPGGDKPTKKTHLKYRCGDCGKAHMREGWRAGRLTFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU50</accession>
    <name>V6DU50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6541" checksum="0C076BC6C18A8491" modified="2014-02-19" version="1">MTFWNLPELGKSHLPNTERVVARVPALFSLKRILNHSVKQACEVTDRFQHFWMIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU51</accession>
    <name>V6DU51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6866" checksum="8136A86327BF06D6" modified="2014-02-19" version="1">MKTYRLNFKPYLNTAGLTTARVSLKSQCQIVMRTSQVADRLVSRRLPATVPVASRAEQAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU52</accession>
    <name>V6DU52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03334</name>
        <name evidence="2" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077267.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125727at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7857" checksum="2CEE6AC6B4A9570C" modified="2014-02-19" version="1">MRDRLTSDLGVYALSGLFSLVVFAIALGILSRTLPGGLASRQLGGLVVGYLLFVGVYTTAWFIYTGIDSREEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU53</accession>
    <name>V6DU53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metal-dependent RNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C450_20761</name>
        <name evidence="4" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="3">
        <location>
            <begin position="44"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="158" mass="17504" checksum="AB2460A4C3F3E5E8" modified="2014-02-19" version="1">MPDTAHPWLPKDTDETFDPLEHADIEPSPETPLVITPRGGDREVGRSCYQVDTEHGRYLVDCGLSQGTGDKFPDLRGLQPQSIDAVFLTVGTETNVDMAAISPEEIDSTGYTELEDQIDHLYDLLSKLNEEVASARNEAGLSEAEIREVVQDEMETKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU54</accession>
    <name>V6DU54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail tape measure protein, TP901 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C481_11025</name>
        <name evidence="4" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077249.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97497at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010090">
        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10145">
        <property type="entry name" value="PhageMin_Tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01760">
        <property type="entry name" value="tape_meas_TP901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PhageMin_Tail" evidence="3">
        <location>
            <begin position="87"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="886" mass="94164" checksum="44016F4DA0B94BFB" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU55</accession>
    <name>V6DU55_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11971</name>
        <name evidence="2" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076529.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97111at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="196" mass="22285" checksum="6AECE2F58CE315AC" modified="2014-02-19" version="1">MAKVSIGLRGWRFEEDEIFTGDEELKPLDEIPEDSRERLLRLVSLVEEPCDVCYLDYGEAEVHRCNEAEIVYGEPDGEVLLCPEHEPDLLYWFREAGGSDHKGSVEFADRFHEWVAAGNEAPEGYAPVEHVEEDPDGLPDLPDQQEVQERLEEGFDGDRIDILELAGERADDDETVTDEEVVESDLDLSTDYPSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU56</accession>
    <name>V6DU56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PUA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03553</name>
        <name evidence="2" type="ORF">BN903_143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090304">
        <property type="term" value="P:nucleic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040777">
        <property type="entry name" value="DUF5591"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17884">
        <property type="entry name" value="DUF5591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5591" evidence="1">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="210" mass="23756" checksum="8631D59D17E0D8C9" modified="2014-02-19" version="1">MRDAEVTAASAETLDRVEIRRFADRVTSRYRNRFDDQPLVLVPCSATKPYSDSQSHRQFHDAIKWRGHTVSMTSPIGVVPQELETTYPAQHYDSVVTGDWSEDEIEFVAEVLRRYLTRNDYSRVVAHVPEDGYREICERVEADPEIDVPFEYTCVDHPTTDESLGELNAALQGEPAYSKREREHNTVRALADYLLGDGAGDDLFGGAGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU58</accession>
    <name>V6DU58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5497" checksum="17AB717F07571320" modified="2014-02-19" version="1">MCLKKRVSTGLTEFQYSALLKASEVDSFLLSTTHESLNTDEGCATRGEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU59</accession>
    <name>V6DU59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4423" checksum="8AAAAF85330C15B7" modified="2014-02-19" version="1">MRLTGPLDADPTPHVIGEQYGLSARQTAPRWKATRLRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU60</accession>
    <name>V6DU60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Creatininase</fullName>
            <ecNumber evidence="4">3.5.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_00851</name>
        <name evidence="4" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.10" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076531.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84020at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047789">
        <property type="term" value="F:creatininase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="29055" checksum="D83B5430C404970E" modified="2014-02-19" version="1">MYLADHTWPELGDALSPGSVALVPLGSTEQHGPHLPLATDHLIAEALATAAADRSDAFRTPTINVGVSPHHRQFPGTMWVDPPEFRDYVESFSRNLAYHGIDRVVFVNAHGGNVQHLREVGRRLHEDEVAYAVEWMWDESIPELVDELFERNGPHAGPKETAMITHIAPDLVREDRLEDARDGGLVDLDDSDAVVHGARTFYDSIDNSPNGAFGDPTDVTPEKSERLFEAAADQLVQLAEWIGDRDRDELFPEPRVEREDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU61</accession>
    <name>V6DU61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rieske iron sulfur protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_03573</name>
        <name evidence="6" type="ORF">BN903_148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077298.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102560at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="16347" checksum="B0A50F0EF140AEE2" modified="2014-02-19" version="1">MSDYRLTTVETVREQGSWAFTAREGDTDREVFLVPCADEPDGEAERSDRAVRAWINRCTHEDQRLHREEVGAVTRGESVVCPKHGSAFDACDGSCDNGEAAGTTLREIDVAVRDGAVFLTDDDLTYLYEGLPDDDGDDEGPASSSHLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU62</accession>
    <name>V6DU62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8214" checksum="5569EBE6922A3F68" modified="2014-02-19" version="1">MLGPIVRGYQRTDLWHTARPFPALADKYTATTPAFGPHSGINECILNPDTRPHRDRRDENRSGVRRSRSTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU63</accession>
    <name>V6DU63_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11324" checksum="A8D571DD3DEF7ECB" modified="2014-02-19" version="1">MRGRRMFQTICCCWVNHSGLAEPSRNARHASRLNRIWGSKTAPHASPSVSGKAPKLTWRSVAPTNTARLPSATPASVESAYQRLAAARRSPSLSNSSAIGPTDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU64</accession>
    <name>V6DU64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_10044</name>
        <name evidence="1" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015001">
        <property type="entry name" value="DUF1850"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08905">
        <property type="entry name" value="DUF1850"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="176" mass="18753" checksum="08F2347882754075" modified="2014-02-19" version="1">MIPGFRGALRATAGRRRIAAAALVGLLVVAVVAATVGGVPGGDSGADRTLVVTHENGTELVAAPVGDDTEVVIEYTHSVEKTLVRDVYVPTDDGIRMTRMEFSSFGAGLPSRADVTERDGRYVYYPPPTEYRTLHLKTGLVADHDLIVGDRRYDIAGLSEGGAVELTVERRGLFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU65</accession>
    <name>V6DU65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Basic membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_03603</name>
        <name evidence="4" type="ORF">BN903_154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077302.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="22162at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Bmp" evidence="3">
        <location>
            <begin position="69"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="383" mass="39549" checksum="ADA24654D347A27F" modified="2014-02-19" version="1">MASDFERRRFIKAASAAGLIGLAGCSGGPSDGGDGSDGDDGMDGSDGEDGSDGSDGGDGSDSPPARVGIVYSDGGLGDNSFNDAAKQGIVDAEEEFGIEYAESEPDGTGEFGQYQQRYASSTDPNYDLVSCIGFNQGDALTETASQFPDQDFMIVDTVVDSPNVANYLFREEEGSFLMGVLAGRLTETDFSAGGGSTAPDSTNVGFIGGVDSPVIRRFQAGFEAGVDYASDDVDVSTSYVGSYSDPTAGQEQALSMYQSGADIVYHAAGATGVGVFQAAQSEGRFAFGVDQDQSVTEDSFADVILASMVKRVDTAVYESISNVVDDDHQGGSTTALGLESNGVECVYGQEIGDQVPDEIVTAVSDARDEIIAGNIDVPDTTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU66</accession>
    <name>V6DU66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cu(I) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14912</name>
        <name evidence="2" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008719">
        <property type="entry name" value="N2O_reductase_NosL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05573">
        <property type="entry name" value="NosL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="16996" checksum="AEE338197685A427" modified="2014-02-19" version="1">MVIGDHGGPNGQVFYADAEPEPRQGPAEDAEDTAHLAWFHTLAHGLFPYHFDMVDDGAEATAIYVTDYSRVNWEIPEGTERKKMPAPTAPDTFADATDLTYAVKTDVMGGMGPDLLPFSDSDEAETFAEDYGGRTLGYDEIDRQLLEGIQMTGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU67</accession>
    <name>V6DU67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C468_06103</name>
        <name evidence="2" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077281.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69271at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="161" mass="18400" checksum="713F5246F9A1192A" modified="2014-02-19" version="1">MRETVLYRSLRNHFEADTPWDETALFAVLTEEIDAGRAVWHDCDTEAAVRRRCERLDDLYETLRRDGYRSQLELARRNRVAPGPDAFPRVMRHEIAVDVSRDGEPLLVEGKHRLMLADLLGVDSVPAVVYVRHPEWLAKRDAAGTEASGRGRRSDSGAERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU68</accession>
    <name>V6DU68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C470_14693</name>
        <name evidence="4" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076825.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81806at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="199" mass="22941" checksum="68419E60270F8065" modified="2014-02-19" version="1">MADEPASDILDATHRTLCEYGYADLTLQDIAAEADMSKSSIHYHYDSKDQLFVTFLDELFDRFINRIDTPEGETPHEQLDTLLQVLLTSDTHPDVREFRTAMLELKAQAPYNPALQERLTKFDEFLFEQFREVLAKGVTTGQFDETIDPPRAAEYLTTVITGAHTRHVAINQSSDWLYDTMTRYIERHLLADEYTEVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU69</accession>
    <name>V6DU69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transcriptional regulator containing an HTH domain fused to a Zn-ribbon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_14419</name>
        <name evidence="1" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077259.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107730at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038767">
        <property type="entry name" value="Transcriptional_reg_pdt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40663">
        <property type="entry name" value="PTHR40663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="10710" checksum="8B47CFCB050E097A" modified="2014-02-19" version="1">METTRQRIADALREEPRTASDLAATLSLPTPTVYEHLEHVSRSITEADGDGGEEFLVAPPTCRECGFDGFDDPVNEPSRCPECKCERIEEPTFVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU70</accession>
    <name>V6DU70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
            <ecNumber evidence="8">3.6.3.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_14932</name>
        <name evidence="8" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.28" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076541.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="59367at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="7"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="271" mass="28265" checksum="91F50F8C5F769D9F" modified="2014-02-19" version="1">MSERVLAEVVDLTRTYGGIRVLDEVSLSITSGITTVVGPNGSGKSTLLGVLAGAVEPTAGAVRYAHEGSTDDGSDKRIGYLPQRVPFRGEFTARETLGFYAALVGDNPDAALADVGLADAGDKRVSALSGGMRRLLGIAQATLGDPAIAVLDEPTSGLDPEMRERAFRAAAARASDDTAVVVSSHDLDLVDTYADDVVVLDRGRVAVAGSRDRLVDDYGVDDVKGLYRAVVNDRVSAESDIDTGDTDGDDDSKDVNEAAPESVHVTGVSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU71</accession>
    <name>V6DU71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5572" checksum="D45E156B23EAF0F9" modified="2014-02-19" version="1">MRLRPWVVYKDEVKEGVGRTPAIGASTCRSRVSVRIGAERGDGSGRTQGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU72</accession>
    <name>V6DU72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="10">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C496_03843</name>
        <name evidence="10" type="ORF">BN903_126</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="10"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="18"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="219"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="430"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK39727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="639" mass="69731" checksum="05DB9508E4060217" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU73</accession>
    <name>V6DU73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">L593_06755</name>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076827.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90282at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13398" checksum="14182D8A2D5921BE" modified="2014-02-19" version="1">MEEISTDDAPDAIGPYSQGVIDDGQVYVSGQGPVDPQTGKVVSDDVTEQTERTLKNVDAILEAAGSSLENVVHANVYVTDMDDYETVNEVYAQYMSEPYPARAAMEVSRLPIEIAVEIEVVASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU74</accession>
    <name>V6DU74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C485_13555</name>
        <name evidence="7" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077264.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57897at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="122"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="36596" checksum="0B32C33E4E732F10" modified="2014-02-19" version="1">MWDEFQEYLTYLQVDKAVAEKTLQTRSRSLEDFTNYCESNEIYDISEVDRRTISKYIDYLVAEGFAYNTIMKERYLSIGATLRFLYRERRMDKSVMERVDNSAMKRKARNAMSAQEKKDENEPPAHLSKAEVYELAENVGPPSDRNSLLIKLMFWTGIRASEAELIEIGDIDLEAPSISVYSPKTDTTRTVSYPAPEINPELRDWIHNGRLRYKDADASDRLFLGENGPINKHRINKVVRNAADTAGHQKEERTTKDGNTRLESTAHILRHSHAMYYLNEEGKSMEVISQHLGHSSLSVTEQFYAQTTEKTLIDEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU75</accession>
    <name>V6DU75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_14947</name>
        <name evidence="1" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076543.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115607at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="167" mass="19307" checksum="CF67080B5CC47AEA" modified="2014-02-19" version="1">MPDTRTQIRRHVCDTPGVHFNQVGRDLDIATGQVQYHLRRLVRNDELAVERIGGRTHYFAPSFDPWERRALAFLRRETTREILVRLHADGPKRPKTLASDLDLARSTISWHVSTLAENGIVEKSDDRPMTLTLNRPERTAELIETVSPSLPDRLVDRFVRTVDELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU78</accession>
    <name>V6DU78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="16006" checksum="652EA595E0FB8906" modified="2014-02-19" version="1">MNSSYILPISRRISLTQSAQKGVNDLTASVAHSFDYGQASCYILFRSYRQLVADVRARDERLVARAGDDESALSIASSVSAVSALSCSGRSTVIVATPRSSTSNAMGSLLIRFSSRGGMKTIRQADPAFGGRILVSVVRPLRGCRSRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU79</accession>
    <name>V6DU79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C437_13075</name>
        <name evidence="6" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076831.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57718at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="75"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="281" mass="31245" checksum="F77456222ACB94A6" modified="2014-02-19" version="1">MTMAGQQRTWLRKVRLYGVLIALLGVMMFPFYAMFSSTLKRESELFSSPATLVPEDLTVEAYLQVWSQTDILLWIANSFLISIGTVVLTLALAIPAAYSCARNDFIGKRTFLLSVLVVQMFAPVVLIVGLFDVITTVGLFNSYLAVIIPAAAFTLPFNVWMLYGYFKTIPVSLEESARIDGAEQWQILTKIVLPLTKPALVASVTYTFLYAWNRLLFVLTFLTDAGKYNVPRGVFSMVGALQTDWRMMLTASVVGIIPLLILFAFLEEYIVAGMTAGAVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU80</accession>
    <name>V6DU80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C463_10860</name>
        <name evidence="4" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="3">
        <location>
            <begin position="67"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="350" mass="37786" checksum="D79477AB92860C84" modified="2014-02-19" version="1">MSDGGRTDECDICRQPIAGGSVSGDSDGAFCSTGCRDIDRALGRADTPDRSPTGAAPERSHSDAVTRTFFRIDGMYSSTCEAYLEHIADTQSGVVAAEASYVTETIRVDHDADTVSVDDLRDALSRTGYTAFLRSEANADGDASGTRRSREADGIRKRRSDEVLGLRYAAGIVFGAFLMVPYVAIMYPTHLAPYVDATFLDGFEGAFQLSGSSGFLFLRIYFVLTVIVLFFTGMPVLRGAYLSLKMRRPTTDLLVAITVVSAFCYGTGAVLLGDNNIFYDLTLVVAAVVSGVSFYETSIKQRALERLTELTVSQVDSARRLDGDDATEVSVDSLAPGDRILVREGERVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU81</accession>
    <name>V6DU81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Archaeosortase A</fullName>
            <ecNumber evidence="12">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">artA</name>
        <name evidence="12" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="12"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077325.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100786at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014522">
        <property type="entry name" value="ArtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025737">
        <property type="entry name" value="Cyco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04125">
        <property type="entry name" value="exosort_PGF_TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="9">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR025737-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR025737-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK39769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="320" mass="34736" checksum="0B543E24FF358B85" modified="2014-02-19" version="1">MFGHGVPAVLSVIPDTFTFAWIVAVLFAASWLLDSRGLDAGRALAAATWALFGLFWLSTVPYFAFEHQSYVEAILALVGFPASVYAGYLLYNGRASLFTLTRAIAFMLFIYLPFETIPAFTVAGVAVPEPRRILIEVVAAQTGTLIDLLGYAPEAVTSSEGYDAAYSWTLADGHTVVIHIVLACTGLGSIAIFGGLVAAVEAPLSRKLRALAVSVPLIYVLNVLRTTFISVVAGNQYMHWYPDLVLAMFGASDPYRVSFLISDRIMSQLLAVVALIAITFLAVRELPELAVILEDVLYLITGEEHDLTEALDLPREPTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU82</accession>
    <name>V6DU82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_08017</name>
        <name evidence="3" type="ORF">BN903_136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="208"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="402" mass="43372" checksum="45A4963200A71BC1" modified="2014-02-19" version="1">MSRLSNLPNPFRALILYIGFALARVGLIDRHRVVRTTDLAWPRIVTGIARMXXXXXXXEAAEDVLGFSVVTVRVHDADAGGLVPAAVSTAAAELLPERETFTAGGGSLNWAAFEADEVRVYDDIREMDALDADTPLRSLMILPIGEFGTLSIGETEPGVFDGTDEFLARILATAVETAFQAEERTRRLHERSAELERQNDRLTEFASVVSHDLRNPLNVAQGRVELAADECDSEHLTAAAAAHERMEALISDLLTLAREGEMVSETETVRLADIAEGCWANVDTSNAALAVETELSVRADESRLRQLLENLMRNAVEHGGDDVTVTVGTLPDGFYVADDGPGIPEDEREAVFDAGYSTSESGTGFGLRIVEQVADAHGWSVRVAESEAGGARFEITGVESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU83</accession>
    <name>V6DU83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7474" checksum="4B50873479868678" modified="2014-02-19" version="1">MDVESVLFETRVVERREVVEDGDVVAVAEERRREVAADEPGTARHDDVHRVTLRVGDSGVASVSAGIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU84</accession>
    <name>V6DU84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Halobacterial transducer protein 4 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">htr5</name>
        <name evidence="2" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="143559at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15428" checksum="458E277F917A293F" modified="2014-02-19" version="1">MSCRSKRGPKNISFRETDRLCSVTPVRSHKQPLRSPSKERTSEINDAAETDTDIREISDTTDDQAASIEEVVTMIEEVSDIGRKTANESDSASAAAQQQPASMSQVSDNVESLSGRAKQLRELLSTFDVSESALLNPQKAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU85</accession>
    <name>V6DU85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10906" checksum="4B6598CC5EF2C511" modified="2014-02-19" version="1">MEVVELAEFEPFRPVVGPATLGVGQRTVLAGLPVADLQEPLADVRRGAVGTADDDRYHAPDSAARDRIPVGSRRGRGTAGLRSVLWGPRPRYGSNRYTKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU86</accession>
    <name>V6DU86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C447_16299</name>
        <name evidence="3" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="29410" checksum="A9082A642D6097F4" modified="2014-02-19" version="1">MTANVAMILPDSFPPDIRVTKEAHALGEAGHDVRLFCPTEPDRPDRETIDGIDVVRVRTGERTGLDRLRRNLSVALTGYRPEWAAAVAAHGDWIDVIHVHDLLLAGTALRVGDHLDAPVVVDCHENYPEAVRQWRRSDPAWWRSPPDFLRTPRVPGVAVQAVRTPLDEGGRPTAHRGGRGRAALRPRLRRPPDRRDGRRQHGLRRGVRPRDAPGTRRRRGLVRRRLRRVVRPAPRPRNGAPGDRGRRVGTPRSASPPRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU87</accession>
    <name>V6DU87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5316" checksum="768A55727701ECC6" modified="2014-02-19" version="1">MAESASRTGWKVRISHGIIPNSVRIVHYWTTLELSPSDKTAILTTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU88</accession>
    <name>V6DU88_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diadenylate cyclase</fullName>
            <shortName evidence="6">DAC</shortName>
            <ecNumber evidence="6">2.7.7.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cyclic-di-AMP synthase</fullName>
            <shortName evidence="6">c-di-AMP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C467_00936</name>
        <name evidence="6" type="synonym">dacZ</name>
        <name evidence="8" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the adenylate cyclase family. DacZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076550.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80301at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019932">
        <property type="term" value="P:second-messenger-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00840">
        <property type="entry name" value="DacZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014499">
        <property type="entry name" value="DAC_DacZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045586">
        <property type="entry name" value="DacZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19294">
        <property type="entry name" value="DUF5912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019073">
        <property type="entry name" value="UCP019073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="7">
        <location>
            <begin position="109"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="28929" checksum="9BF3FAF048615052" modified="2014-02-19" version="1">MDSLTDHLADLVADVDATLLFSPTSSFYDRFADDGVEVVVVAPENDVDAETFVELPLPFDNVKDRIRFGIEGAMDEGLLSEGDEVACVVSVFDGGSDAVIRVTVDETIHTGIYDLFANSRAEPSVIRDVFEVAIELGQKGQKGKPVGALFVVGDAGKVMNKSRPLSYNPFEKSHVHVGDPIVNVMLKEFSRLDGAFVVSDSGKIVSAYRYLEPAAEGVDIPKGLGARHMSGAAITRDTNSTSIVLSESDGLVRAFKAGELVLEIDPEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU89</accession>
    <name>V6DU89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6580" checksum="14DD486A3CBF2C47" modified="2014-02-19" version="1">MSLPRSRSKRPIPPYPRSEAKGLTSAGESEGRAARTRVRSSDPSNAAAGPTYTSGFGGRCER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXZ0</accession>
    <name>V6DXZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13252</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045466">
        <property type="entry name" value="DUF6498"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20108">
        <property type="entry name" value="DUF6498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="425" mass="45286" checksum="674DD3872DFF348B" modified="2014-02-19" version="1">MVALPRSPDASRSAAVAVGIANLLPLVGVVALGWDATTLVTVYWFELGVVAAFAVLRGVFAGRPSGFDANVLVFGAIVEKRLSVPVPRTGVRVHLSSLFSLAVLVPFLAVLWAVTGPILLALAGAEGVRPETVGTALLAAVGIAAAEALRTAVDYFYRGGYRDESAGTALRGVLLRMATLLLVGFFVVPLVAAAVADDADVPIGEVAEPTTFGPIVLGLAVLVKFAFDLAALYGDRLVVFDESTDYDLGWAYDLPARERDLDPVPDPDRRLRPTGIGRVLGHPLAGIRRPGGWLLAAFLATATLLAGISGATLLAVGLALLAVTAPVTAPAFDSLIRYGPLEYRIDDEDPSIVAYDRLFGGVLWRIEPWDEEGLRVERDRIDRLTATRSVVVELRDREVRLPRLADLGPVLDVFDRRAERPDDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXZ3</accession>
    <name>V6DXZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-lysine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_11415</name>
        <name evidence="3" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="22789" checksum="4E0E4B83D371FE7F" modified="2014-02-19" version="1">MINGEPSGCGGVTLGYRGLLEGTYVNTSESGHSSRPEPNAIQHAIDWWHGVEETFTPDDAETAVFDQVTTKPISIDGGLSEDGLAVETTMDVQLRVPPSRPVDEIHELAEAERGDRLGPGGASRSPPVMESPRTDLARAFRVAIRSAGGDVRLLRKTGTSDMNLFAAAWDCPMVTYGPGNSDLDHAPDERLPLPDLDRAVRVLTDVCRERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXZ6</accession>
    <name>V6DXZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6421" checksum="61D6FD68720121F6" modified="2014-02-19" version="1">MVSSPPLNASATLVITGGDTAYALKFSGFIFVRKKLSGRSRRLQSRLHGTKRRERDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXZ7</accession>
    <name>V6DXZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5822" checksum="5EBC43159D7B6D63" modified="2014-02-19" version="1">MSSAATMLYRATGASTLLATVTPSVHEPLGRGDPSETREGYRTLLYESVATFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXZ8</accession>
    <name>V6DXZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5311" checksum="EB04FF4D957308A5" modified="2014-02-19" version="1">MCERGLPARPSDAAGAGLVAFAGVGISVVAVPSALSSKLLRSPRSARGIYITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPF3</accession>
    <name>V6DPF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075967.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119723at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10176" checksum="352FCDA84A62C8FE" modified="2014-02-19" version="1">MAGEKLSIEENRFLRLGTLPAFCPSEQCGEYLTLENATVKTEGGSPFRLQCPECEELIDQACPDCGSKDFQIESGVEECLLCGHLVKVEYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPF4</accession>
    <name>V6DPF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075972.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="456" mass="51570" checksum="338FB796404BEF4F" modified="2014-02-19" version="1">MSDRHASIDQLLTGDGITTESELRSAIWCGDPRVFENHDGKAITQAAKHLTWDGFDFTRLDVDDLSRRSRVLEEVNNTALAVLGPDGNVYQLGDTVRAEVQKPRHGWGRRPDPDETATYETELTRVSELGVSLSFDPTYSNSSGKSASAKPGRDPLELLSRSDLGEYRERLTEGTDIDIPEEVNGWTLSETDEYDRDTNHLQNNLITKIQWCNGESTYITAKWRGGYNCWYLTAPIPGTLTDANQGENDYLYEIDVPQRVVTSQEIISLAVKAMESLNPAHFQSAYDLRDADEIDSLRDQRYGPAPVSFPKQLGDWTRESIHPYEVVYANSREMCPWDGYQVKIDMHGGVIVKNEADSVVHDRRLVERYFPNGEPYPANIDTHDYVGESRDMFDENWYYGVAFMAQSSKARPDHTTLETLEQHTPADISLMTFDHGLSTNATESQDRENGNLFAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPF7</accession>
    <name>V6DPF7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15647" checksum="EB5BEE32F81CC5D5" modified="2014-02-19" version="1">MTMTTYPYSDNENRKFTYEETERAVTITHEPEAVSLEFKHVSNPTRTTKVSVIVNRGGLDQFPTDLFDETPFESTAVEVDDWTSFITTDFIELDTYTVLLPVLKALAKYAWIDTMSSLYIHNSDTPAANHLVCVLGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPF8</accession>
    <name>V6DPF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075977.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9200" checksum="98FFAE9999E479F0" modified="2014-02-19" version="1">MTTDKVTYTIESGSIAMREHVANLITEIGNNTPVSVDTSTGDTGVTATVIGDGYELPLIEDSIRTSLPASLQITDTDVTIGADRSADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPH2</accession>
    <name>V6DPH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="130" mass="14793" checksum="A8598C0521840F4A" modified="2014-02-19" version="1">MELMETPVTQAQAQQALEATFEEEDDQPDLEVFMALLREYQAYFLDEELEGHLESVHEGYVRIYAAYADCFVIETSYDAHSIGLGELGYGHQPLQRAVMNAHRKVAEEIEDEVGPDIYPIALNLPNRTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPH5</accession>
    <name>V6DPH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075989.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="9668" checksum="164C5D8E617788D5" modified="2014-02-19" version="1">MSDSTPDITDVKAWLDDEYNQYMSTYLYDNYLRLTNGSAAHFVDIRITDDEEIQLFGERYGDQIDKRCEATRESLLETLSSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPH6</accession>
    <name>V6DPH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C480_19287</name>
        <name evidence="1" type="ORF">BN903_314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334877.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129107at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="17266" checksum="B8482F6BA41A4A6A" modified="2014-02-19" version="1">MLTESSKQYTVAVAEKVNVSAPNPEKALREVSRVTGLSEQRLSIEAVEDVDNIDGPYVELEFTPQEWIRGRAEPVETEGKRSWLVPVEDAVNDEGVLISPTDFEADGLKDHERAPFWVQNWSGPFSIKIIDIGGIPTDLKELLSNGEPVDDVLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPI1</accession>
    <name>V6DPI1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable thymidylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tmk</name>
        <name evidence="5" type="ORF">BN903_319</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334880.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114844at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="11642" checksum="7D067DF208511929" modified="2014-02-19" version="1">MTGRFISIEGVDGAGTTTQAQAVADELVERHDGLTEDDTLVTAEPTDGEIGRLIRTGLAGDIELSQQALALLFAADRVNHIKTTIEPALNDGKTVITDRYYLSSYAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPI4</accession>
    <name>V6DPI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075944.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="173" mass="19519" checksum="E35A1C2EC546EA3C" modified="2014-02-19" version="1">MNLTKTEYTIAVEEEVTLEAFRNATSDGVNIRWVNIAPIHHRTTAPLDTKRVTHEIIAEMAALCEDWPEDETTLYWNLHIPDTDTLIDPLTNRSIRTPAVPHLQPPPAPIVTACQRWYDDDNEEIEGDSDRALLKGFFIKTTISQDGTVTDAELIARYTEPSNTRAGLNTPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPI7</accession>
    <name>V6DPI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3873" checksum="19C2A844567ECF90" modified="2014-02-19" version="1">MDEAMAKAVEFTFVKAVDTNSAVVVFHSGGSCESGGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPI8</accession>
    <name>V6DPI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075949.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="119" mass="13512" checksum="9813731E35DD64BD" modified="2014-02-19" version="1">MENIPVYLKEILNEATAYFEEDDNISRVGAAHEIAHQHESLVVMDDGERDALELLRDIRTVHTLCGDEFETYRQGRNAEYADSILEAVALRSLEELINVHLHSDQSFDKNEPATAQTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPK1</accession>
    <name>V6DPK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8373" checksum="B7CB9F2E1D83EA49" modified="2014-02-19" version="1">MGDPKDAPTISDFVLITEDSIHGVHFNGDSWERLATRSKPDGAFEGAFITNTDHDHDEYREVVEALDDARADPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPK3</accession>
    <name>V6DPK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="5859" checksum="FC0C9DF54166D3D0" modified="2014-02-19" version="1">MSDTNDTTEAEAAVGNARAFLSDFEDESLEVQHGAIEHAISELQNAKRALPDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPK7</accession>
    <name>V6DPK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076003.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="10253" checksum="87BC8684CCD8C12F" modified="2014-02-19" version="1">MENWTEMPSEHLTGNGYRNIIRGWENTEARLNNEVLVYRTEGTDVEATAEGEFAVQHPLDEEGLNTHFFDDEDAALDYAKEYMKDNPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPK8</accession>
    <name>V6DPK8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dual specificity phosphatase, catalytic domain protein</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">51</name>
        <name evidence="3" type="ORF">BN903_372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334886.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88409at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="2">
        <location>
            <begin position="62"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="15871" checksum="1C2671575E59E824" modified="2014-02-19" version="1">MNEIIPHLHIGDARTARALSEIDNPFDEVVTVGYARVLGRECPRESTTGDEFVFPDGPHEYETFEAAADYVLDAVESGEVTFVHCQAGVSRSCSVCAAVLAVHSGVDVDEARRRVKQVRPRVDPEQEVWSSATRYVDEHPRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN0</accession>
    <name>V6DTN0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0173 metal-dependent hydrolase BN903_189</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_03744</name>
        <name evidence="2" type="ORF">BN903_189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0173 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076642.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76909at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00457">
        <property type="entry name" value="UPF0173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022877">
        <property type="entry name" value="UPF0173"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="240" mass="25667" checksum="C2D86C801EC6113E" modified="2014-02-19" version="1">MELTWHGHSTWHVVVDDTELLIDPFFDNPKTDVDPEELDPDYLLLTHGHSDHIADADRFEGATVVATPELTSYVQENFGHEHTLPAAGMNIGGTAECGDAWVTMVRADHSNGIDNGYGTSAGMPAGFVIGDKKPTQESDADCTTFYHAGDTGLMSEMVDVIAPYLEPDAAALPAGDHFTMGPAGAGIAADWVGADVVFPMHYDSFGPIEIETREFVNEVKAAGAAAEPVVLDGDETYTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN1</accession>
    <name>V6DTN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08069</name>
        <name evidence="3" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077156.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104239at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="14351" checksum="594466BA0C46F8AB" modified="2014-02-19" version="1">MDEIEDVFVARLMSTDLHTVTPDTLVEDAAAVLLENDISSVLVVEEDDGALVGILTSTDFVDIVAKSQPKAETTVERYMTADPITASAQDDVSAVAATMLEHGFHHVPVVDGDTPIGIITTSDFAAYVSSPESVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN2</accession>
    <name>V6DTN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4668" checksum="A7E99F97665E6B4A" modified="2014-02-19" version="1">MKPRSNRSSRNYTTTFVIPAAFIISEQTMGKPTVSSQFECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN3</accession>
    <name>V6DTN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_05659</name>
        <name evidence="1" type="ORF">BN903_121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077171.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115656at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043952">
        <property type="entry name" value="DUF5783"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19095">
        <property type="entry name" value="DUF5783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="13080" checksum="937A83B40523271A" modified="2014-02-19" version="1">MADEFDPEKFEDKYAHYFNELQRAYKNAFNQMNDRYDSELIHGIDQTVLNESEPFYEDGEFRVELPENPRERIRGAVAVDDETFEETLDEYVERIESELYRTLGVDRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN6</accession>
    <name>V6DTN6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="4 6">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">nadE</name>
        <name evidence="9" type="ORF">BN903_94</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00193">
        <property type="entry name" value="NadE_ammonia_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022926">
        <property type="entry name" value="NH(3)-dep_NAD(+)_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="268" mass="28743" checksum="0020F42665179A84" modified="2014-02-19" version="1">MLSDDPPLDLRLSESELEATRERIVSFVSDVVDDAGAEGAVLGLSGGIDSTLTAHLAVEALGEDGLHGLTMPSAVNDADVMSDAERVADDLGIEYDVVEIQPIAEAFFDAFPDAADDRTAAGNVYVRTRAVLNYFVANAEDRVVLGTGNRAEAMTGYYTKYGDQAVDCNPIGNLYKQQVRQLAAHVGVPRELVMQEPTAGMWEGQTDAAEMGLDYDTVDAILAVHVDGGLSRSATVRELDVPEEAVDRVVDLHERSAHKRAMPPAPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP0</accession>
    <name>V6DTP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C485_13510</name>
        <name evidence="1" type="ORF">BN903_199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076651.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122587at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="7667" checksum="9527B1EB324F1E74" modified="2014-02-19" version="1">MEDTHTEDKECTEQQILRRLPGFHLDSGSPCTCGVDAIRTSKSVGYSDFVAYTHSCTECGNEFVTYIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP1</accession>
    <name>V6DTP1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Siroheme decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.111</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_08109</name>
        <name evidence="7" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 H(+) + siroheme = 12,18-didecarboxysiroheme + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:19093"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
            <dbReference type="ChEBI" id="CHEBI:140497"/>
            <dbReference type="EC" id="4.1.1.111"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Ahb/Nir family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.111" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040523">
        <property type="entry name" value="AsnC_trans_reg2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17805">
        <property type="entry name" value="AsnC_trans_reg2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg2" evidence="6">
        <location>
            <begin position="108"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="208" mass="23161" checksum="F7EFE3FEE85E39C5" modified="2014-02-19" version="1">MLALPMLTDYYIDLEFPVVNGDRFARESLDETDVSATRISENARGDLSALEADLLFAIQDGFPLSATPYADVASEVDADVDDVLAAVERLLADGCIKRIGCIVNHVVTGFTNNCMVVWDVPDDELDERGEVVGSLPYVTLCYHRPRRSDQGWKYNLFTMIHGREADAVDAKIDELAADHLPFDHERLYSTETLKQTGARYKDLVADAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP2</accession>
    <name>V6DTP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="280" mass="30873" checksum="5B55A83519BA5E9D" modified="2014-02-19" version="1">MGTGLALRVGLHEEPAEVRDQVVYLVGLSPPPLADTVVERIGGVEVADQHRCREVHREVRPNSVPPEHRRQPGEVFEAFGFEELPPLERVEGGVGAPAVGLDRVDVVEHDAVDPHRREQAGVVLVAVSEVGQPLPVEDRLAAVPALDRPVERRVPLVDHAVCGRRLLADVEVVDRFPGTQQAEEVEGPVDEPPVGRRGDDDTVSAVPRHRAHEVSAVIEAVDVLGGNRVGDHRHVVRRADGEEPVDRRRRVLPEVRLPIEKRRDRPTEFVTDGATLRRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP3</accession>
    <name>V6DTP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10574" checksum="43D5B96DEB3674BF" modified="2014-02-19" version="1">MEYYSDLNALPYDPVFEIEFECKNCGKEFSRKFDSNVEVRPAGAIGPNFRGIDEVHGNRYVAVIDGDKYPIECDNCDIDTSLYELNREPLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP5</accession>
    <name>V6DTP5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps12P</name>
        <name evidence="2" type="synonym">rps12</name>
        <name evidence="6" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004599087.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38945268"/>
    <dbReference type="GeneID" id="65214674"/>
    <dbReference type="OrthoDB" id="85293at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_A">
        <property type="entry name" value="Ribosomal_S12_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022863">
        <property type="entry name" value="Ribosomal_S12_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_S23_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15562" checksum="DCF159BDB733DCF3" modified="2014-02-19" version="1">MANGKYAARKLKKDRQKRRWSDSEYARRERGLKKKSDPLEGAPQARGIVLEKVGIEAKQPNSAIRKCVRVQLIKNGKQVTAFCPGDGAISFIDEHDEVTIAGIGGAKGRAMGDLSGVNYKVEKVNGVSMIELVRGNAEKPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP6</accession>
    <name>V6DTP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08139</name>
        <name evidence="3" type="ORF">BN903_104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077164.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119032at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043808">
        <property type="entry name" value="DUF5790"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19103">
        <property type="entry name" value="DUF5790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="133" mass="14038" checksum="EFFC7F396F921416" modified="2014-02-19" version="1">MAQSTFDDDDLFGEAAEETRAEVEEHLAAAREQLPDPDAVWETDADNVLGALNGLKSALDAGDAIDSVRSAKKAYVLGERADAFEDADDLEAEIEELESLVGDIESAADEVASLTGTIPAIRGALQDAADDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP7</accession>
    <name>V6DTP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_13310</name>
        <name evidence="1" type="ORF">BN903_253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076356.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115895at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="119" mass="13259" checksum="20E1B21CA6FD2655" modified="2014-02-19" version="1">MTRYVPDCDDGRLTLVSEAGDDRVDIGTIDDVITAIGDSTHSIEYDQKQRTQPWLDTDDGTLAIDVREAVTTLPHTDETVDELREYDMSTERYGLPLRTVKFANELLDILDAQGTADPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTP8</accession>
    <name>V6DTP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6357" checksum="629C9E9446DB35C7" modified="2014-02-19" version="1">MPNHFRGSGLQIHSNPRNELQSDENPRPRCPRSTAKLLFLCSLFTSHSLYFREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ0</accession>
    <name>V6DTQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_05574</name>
        <name evidence="1" type="ORF">BN903_136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10182" checksum="52AFBE7C5D7AF678" modified="2014-02-19" version="1">MRLAGAPNGSASIDPAGDVAILTVTLVAPDGSTFTYRQEATVRTLDSDRVEVVWPPERWVCRLVTECGSEGTYLPDKSGVHSEWVVFETVAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ1</accession>
    <name>V6DTQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08174</name>
        <name evidence="2" type="ORF">BN903_109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="24116" checksum="7583E18179612FE3" modified="2014-02-19" version="1">MSQSAPTREVARRVFASEFNDAGYTFTESDDERAPVYALLPTGESSNRVFFVGTLTEKEDVGDDSEYWRGRIVDPTGTFFVYAGQYQPEAASKLRDLESPAYVAVVGKPRTYETDDGTVRVSVRPSRSPRSTPPLATAGSPETARRTVXRVAAFRRRGQRXXXXXXXTRRPRRRRRRRRSACPCRAARAVRAVPCCRPGGTRRRHRRRGRRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ3</accession>
    <name>V6DTQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEPN domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076657.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007842">
        <property type="entry name" value="HEPN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05168">
        <property type="entry name" value="HEPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN" evidence="1">
        <location>
            <begin position="141"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="264" mass="30931" checksum="4F1B163AFDAA63D6" modified="2014-02-19" version="1">MSEEIEYSDEFVENFLDNTFELWFEDALEEKGLERNDFEKGQVFLKNPFALSQFEDLESGDSDVEVRVNDDAEVRIMAEIDTDREIEEGDPIYARDIQGFDEVILDEEQEDYGHVIVADLGKFGWYFNFDFRYNRSYADPLIDAADQFIEMAEYAEENELWRGFVENAFHAAERMMKIDVIFLGWSAEGHSDVQARYSDLVQMGQGNSDLYDVFNQLKGKYRFSASYVDPRGDVDEREFEFSEDEAEEFLSVIKEHRETMSNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ4</accession>
    <name>V6DTQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7591" checksum="24FE3464D708BFC6" modified="2014-02-19" version="1">MASPATAPQRGIEALSSSSEIGYFWLAVRTLCVLTTSRKALRAFRTTANVRPPRGWGFGGLGHGVALGESTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ6</accession>
    <name>V6DTQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FeS assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sufD</name>
        <name evidence="1" type="ORF">BN903_141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077187.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19042at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="404" mass="44731" checksum="C961D77AB52D028D" modified="2014-02-19" version="1">MSTQAIESLSEDTVRRIADERDEPEWLLETRLDALAALETAELPDVIQTPGRRWTDLEALDFEALVDPLNQADATERTAGDDEAVVLPFTEALAEYGDIIEANFGSVLDPDHNYLTALSVALFTTGTFVYVPEGVDVEDVTVRAEMNSRSLFSQTLVVAEESSSVTILESIETGESEVGDDRYFSNLVEVVAGENANVQFGSLQNLDTDSYTYSLKRGVTDTYATVDWIESNFGSKLTRSDIETELNGDGSESQIVGTFFGTDDQHFDINARVWHQAEQTTADLVTRGVLDDVARSVYEGVQDVGEDAWNTSSYQRENTLMLSDDAEADASPKLIIHNHDTEASHSATVGQVDAEDLFYLESRSIDSRTARNMLVEGFFVPVLEEIAVDEFRDDVEELVVERLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ7</accession>
    <name>V6DTQ7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Isopentenyl-diphosphate Delta-isomerase</fullName>
            <shortName evidence="6">IPP isomerase</shortName>
            <ecNumber evidence="3 6">5.3.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">IPP:DMAPP isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl pyrophosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">idi</name>
        <name evidence="9" type="ORF">BN903_219</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="3 6"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076658.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68553at2157"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00202">
        <property type="entry name" value="Idi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018427">
        <property type="entry name" value="Isopntndiph_ism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="59"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="204" mass="22864" checksum="D4E8360A3350B2CA" modified="2014-02-19" version="1">MSSEDATASGDPAGDGAAETGDTGDTDHENALQDVIAVDPDDVAQGTVNRLDAHTGDGIRHRAFTCLVFDRDGRILLAQRAPDKRLWDGHWDGTVASHPVEGQSQEDATEQRLEEELGISPDQYDDLRVTDKFEYKRYYPNEGVEWEVCAVLKVTLDDTGLDPDDDEIGGMLWADYDHLHENPALYRQLRLCPWFEIAMRRDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ8</accession>
    <name>V6DTQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3793" checksum="2AB26D0D14176542" modified="2014-02-19" version="1">MNPIPVVPARPTIKVPTLAVGASDQGVNVSDSASSETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTQ9</accession>
    <name>V6DTQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4688" checksum="59BB6A49C561FD63" modified="2014-02-19" version="1">MDVHITLTLFEASYGMRETQNNLEIQFQPLERYVRAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS0</accession>
    <name>V6DTS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08344</name>
        <name evidence="2" type="ORF">BN903_134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_oxred_C" evidence="1">
        <location>
            <begin position="36"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="170" mass="18366" checksum="65F24791B5971FC3" modified="2014-02-19" version="1">MESALTGDDWGDPLLERLRGEYGNHVAMGALVEQLPDADSRITLADNRVDDRGNPVPRVEWTVGDRALDTIERAKEIQVEVLAELGADIEWVAGPDATGPAYHHMGTTRMSDDPDRGVVDADCRTHDLENCWIASSSVFPTSGAMNPTLTIAALALRVGDDVAGWLSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS1</accession>
    <name>V6DTS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit</fullName>
            <ecNumber evidence="3">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdhA</name>
        <name evidence="3" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077206.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="46312at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03181">
        <property type="entry name" value="PDH_E1_alph_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="2">
        <location>
            <begin position="37"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="367" mass="40862" checksum="931625AD34B1E4F8" modified="2014-02-19" version="1">MTVFDRAYDDTVRVLDEDGEVVGDVPDLDDDSLVEMYRHMRLARHFDGRAVSLQRQGRMGTYPPLSGQEGAQIGSAYALDDDDWMVPSYREHGAALVHGLPLKQTLLYWMGHEDGNNAPPDVNVFPVAVPIASQVPHATGAAWASKLRGENDAFVCYFGDGATSEGDFHEGVNFAGVFDTPTVFFCNNNQWAISVPRERQTRSATLAQKAEAYGIDGVQVDGMDPLAVYSVTAAALEKARDPDTDRPRPTLIEAVQYRFGAHTTADDPTVYRDDDEVERWKRKDPIDRLESYLRDEGVLDDERVAEIESSVEAQVADAIDEAESMARPDLRELFEHAYAELPPELERQYESLAALRDDRGDAAFLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS2</accession>
    <name>V6DTS2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="4">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Htur_4871</name>
        <name evidence="9" type="ORF">BN903_273</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076367.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="7365at2157"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="504" mass="54415" checksum="B8BA651F6BE59631" modified="2014-02-19" version="1">MADVRDSPTVTDYPDPETADHITYNPSLATLRGYSSHVETTTDYGAPAYVSEYRSRSAERTKNAVDDGFGAEDFRVFEQALDWVRDPHNDVVCVDRVVGRHGDAAHVCRLFVPEEYGRIALAWAKLLEPAEGADPDFVTVQVPDATPEPTIRILPEAGVTTVLGSDYTGEAKKSFLRLFMLRAKQRGGLGLHAGSKRVTLDDADGRREVGQLFLGLSGTGKSTLTSHGLWLDDPEGVEMIQDDVCALLPSGTVAGSEGGGLYIKTLGLAADEQPELHDAATDESAVLENVAVDDDGSVHFDEPRHGRNARAVIRRDRLASASEDVDLPTVDQVFFITRNPLMPPVAKLTDAQAAVAFMLGESVETSAGDPSRVGESIRVVGTNPFIVGPEGEEGNRFRDLIATLDVQCYVINTGVVGTDDPVDVGVEETVAILEGIARGTVEWTRDDDLDLTVPASVPGVDVDRFAVADRVDGFADAQAALRADRREYLARFETLDEDIVDATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS3</accession>
    <name>V6DTS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04393</name>
        <name evidence="2" type="ORF">BN903_239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="340" mass="35922" checksum="B27F3281383693BC" modified="2014-02-19" version="1">MLRRGAGLAVAGTAASVAGCTGGGDGGSGGFNAGYAAFFTLNDWANEVAGDRASFEDPVDVGQLGHGWTPDGTLSADVAATDAFVYLDSPEFSWAQDLAATLEDDYDTVAVIDALDGVEDDLLDWDHSHGDEDGHDDHDGEGGNHEGEEGSHDGEEGGHDEQRYDPHVWVDPVLAAEMVETIATGLGEPDPDNADAYADNAAAYADELDAVDAAFESIAENAARDVAVLAGHNSFQYLEARYGFRLHSPVGVSPQNEPTQTEIADTIDLVDSEGMDVVLYDRFQSPRLAESIVENSDATEAVPVTPAGGTTREWNDAGYGYLEQMTEINVPAFERAFGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS4</accession>
    <name>V6DTS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron (Metal) dependent repressor, DtxR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_13309</name>
        <name evidence="6" type="ORF">BN903_139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077186.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110491at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="16104" checksum="0370ADA8C154E90C" modified="2014-02-19" version="1">MNTADQYLKTIYVVQDSEDGPASTGSIADALGVSPASANEMIGKLEERGLAEHEKYKGVKLTDDGIVRARKALQTYCIIERFLANVLAVEDFQAEARELEAVIDDTVAERLDTIIDRQPECPDCFDPETDACACLEIAPTPVEPEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS5</accession>
    <name>V6DTS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdopterin binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_10170</name>
        <name evidence="1" type="ORF">BN903_278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5091" checksum="17B1A1AA5F520BB9" modified="2014-02-19" version="1">MGCYPDREADHNRLKVTATDDDALDDAAAWLLANVDASETPVSRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS6</accession>
    <name>V6DTS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="7011" checksum="C965A9265C52BA47" modified="2014-02-19" version="1">MIRDLLRSNDSSPELSEIRTVCFSTGVPEMCIHLKEEVAPPDDYFADSQIELHYFDIIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS8</accession>
    <name>V6DTS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_04443</name>
        <name evidence="2" type="ORF">BN903_244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076687.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118207at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="224" mass="23269" checksum="604C622664BD28D5" modified="2014-02-19" version="1">MSAGSTLSGRRIGGLYFSGTEIRDLLVAWLALGVAFMLFFVGGWGGIGRILAAGVFPPLFVALATAGVAFLLHEVAHKVVAVHYDQVAEFRADNSMLFLAVMSSLLGFIFAAPGAVHHRGRLTPREHGHIALAGPAVNLGLMVAFVPLFVLGGVLGSDLVTVLGSRGIAINAFLAAFNLVPYGPLDGKTVMGWSKPVWAAVFVPSALLAVGLVFVLGLGFGGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTS9</accession>
    <name>V6DTS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6353" checksum="6E02BD526C5AD63F" modified="2014-02-19" version="1">MPGAKRLQSAPSRSSRTFDIAKYDLLRHRSTTSQNRPRRQKIAERQTKRPIFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU10</accession>
    <name>V6DU10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4518" checksum="BCB2F3D6C8556F93" modified="2014-02-19" version="1">MSRTAFRSRTTPATGREIGSTADPGGAALPRTESRAGRDDPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU11</accession>
    <name>V6DU11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4894" checksum="EB7138A88579898B" modified="2014-02-19" version="1">MVRNGEAVSSSRDAFGVSNDSERLTASRLGLRECRSQGWLHRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU12</accession>
    <name>V6DU12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucuronate isomerase</fullName>
            <ecNumber evidence="2">5.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C471_08760</name>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; pentose and glucuronate interconversion.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.12" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076797.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17433at2157"/>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008880">
        <property type="term" value="F:glucuronate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006064">
        <property type="term" value="P:glucuronate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003766">
        <property type="entry name" value="Uronate_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02614">
        <property type="entry name" value="UxaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="454" mass="51233" checksum="2E2C9296418ACB26" modified="2014-02-19" version="1">MGFLDANYLLESPSARQLYDEISDLPVLDPHSHVDVAALARNEGWNDIWEVEGETDHYVWELMRKRGVSERKVTGDATNREKWDALASVFPEFAGNPTYEWVHLDLKRRFGIEKPISADTADEIWAETKTALDDPAMRQRRLLREMNVEVVSSTDDPTSDLKHHRTLAEELDEVTVRPTWRPDAALGIDAAGWHEYVAELGDATDTDVSDLDGFLAALRTSHEYFEANGCGASDHGLSEIRSKPVDRHRAADVYERAYAGEAVTDDDVADFEAFVLERIGEMNRETDWVTQLHIGPVRDYRDSLYDHLGADAGGDVSTGDLALADGLRYFLNRFDEDLEVVLYVVDPTHYPTVATIARAFPNVSVGAAWWFNDSPHGMRSQLEYVGTVDLLANYGGMVSDSRKLMSFGSRFEMFRRSLANTIGEMVERGQMPMEVAEDRVRQVAYERPAALWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU13</accession>
    <name>V6DU13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077224.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="20566" checksum="C88D7FFAF364C906" modified="2014-02-19" version="1">MSIDISSNDVEYSTSNLTDAEAAVELVGVLDVVTEYRDLLEDIEGDGWFRLRFRDDVSFSDICVLSSAFLLERDTSRNMGAVADWCVTDRASRLLDAVPKDIEITEEESEALFSIGKSMFEIPQAGVGWKLRELKDAEIAPRSLGVLNEAGLLDMTNDPRGHPSTWVATERLDEIKHTLIGVINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU14</accession>
    <name>V6DU14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OSG_eHP6_00010</name>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077240.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="404" mass="43326" checksum="785EF4364E2F0B52" modified="2014-02-19" version="1">MTTETTDTVEHTTTSSNPTGVARCEALEDQSEPYTVHGVAIGANEVTFGSNGPKFWPDTALEASVQSLVGVPLNKNHDDKTVESVVGEVIDAGFEPGVGIVFEAEIDDEELATKVARGRLEVSVHALHGDGGRTSEGEVIVEDVRFLDLSLVPRGGSPSNYVEAGEHPSEVLASLSESDVDAILATSGSDSTTTMTDENTDDIEPDDEESEMESRSPGSSPGEEAEEAEVEADTESEDTEEAEVEADNESGDTEEAEVEADDESDDTEEAELQGDELRDEVATLRSQNQELRNELESVRLEYASQLSEDTAFEAEMLAEKFSFDELRETFDEAEASLVTSNDDTSEATPAPQTGGDGDAELSTGGESESDAEIAELESQIESYDSMGWDAAKRDAEQRLDELQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU15</accession>
    <name>V6DU15_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIB</fullName>
            <shortName evidence="7">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">tfb</name>
        <name evidence="11" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076499.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35979at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="10">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="1" evidence="7">
        <location>
            <begin position="137"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="7">
        <location>
            <begin position="231"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK38708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="35838" checksum="9159BD205BD9F325" modified="2014-02-19" version="1">MERPSRQRQQEQDTERETDESTVACPECDSENIVTDADQELVCEDCGLVLDERNIDRGPEWRAFNHNERQSKSRVGAPITETMHDKGLTTTIDWKDKDAYGRSLSSEKRSQMHRLRKWQERIRTKDAGERNLQFALSEIDRMASALGVPRSVREVASVIYRRALNEDLIRGRSIEGVSTAALYAACRQEGIPRSLDEVADVSRVPQKEIGRTYRYISQELGLELKPVDPKQFVPRFASALELSEEVQSKATEIIDVSAEQGLLSGKSPTGFAAAAIYAASLLCNEKKTQREVADVAQVTEVTIRNRYQEQIEAMGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU16</accession>
    <name>V6DU16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4304" checksum="02D4F286E87E9E1C" modified="2014-02-19" version="1">MSERQRLPALKGSNLADPHTIEIAVFSLRCGGRTSLNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU17</accession>
    <name>V6DU17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7306" checksum="03D5CECE611195A1" modified="2014-02-19" version="1">MTIRPETSTSITSLFRQLIRISTVSPGILWAYTSGFTPKTHDDVRIDLYSRGLAYWDSVGYAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU18</accession>
    <name>V6DU18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11050</name>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077243.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="131991at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="11764" checksum="68FC4AA3DD1934CE" modified="2014-02-19" version="1">MAGITMLGLDGVLDALDYDGFGSRKYRVGTNVEYAVYVEYGTASNQAQPFLRPAVERAVSELDQYASDVDSVDELIEKLAIKIEEYAKKKAPVDTGNLRGSISAQRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU20</accession>
    <name>V6DU20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03354</name>
        <name evidence="2" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="11578" checksum="BED207A163B43AD3" modified="2014-02-19" version="1">MLAVVIGLQNVPDGFAFAVPMAETGMSNLRVFWYTALSGVVPQVVASVFGYLLVGLGTGLFPIASGFAAGAMLAVVFRELIPSSHGHGHADAATTAFLVGFVLLVVVDAVVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU21</accession>
    <name>V6DU21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12166</name>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076503.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="78955at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="176" mass="19717" checksum="5BE0A9EDEC14553D" modified="2014-02-19" version="1">MSDDAPTNDGQQFDRLPETPADREIEGRASRAEVLDWWHERFGIEPAVFEGYSFWEKGAGKVWIFNGEATDPSGVEAIGMTFLRTRQEHWKPTGRAVSRFGRHATRNVIELGPERASRFAAGEDQDLPEWDGDWGYLIATHEVAGESVPIGVGLYLYDELRSVVPKGSRADLPVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU22</accession>
    <name>V6DU22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6523" checksum="7D16299EE7214CDC" modified="2014-02-19" version="1">MWATESRIESNRALSRIQAGQVVDDSAWVCRRLSDVQIDRFLAPISSTIWLFNHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU23</accession>
    <name>V6DU23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11040</name>
        <name evidence="1" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8936" checksum="130E89FF27A8C869" modified="2014-02-19" version="1">MTAFAGSREDYDITRGQRLQAEQMGDEVSRVLGHNQSPSEYLTLAVGPRTDLVDDDASPTEYAVQFQVQYTWTKEPPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU24</accession>
    <name>V6DU24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6744" checksum="6010EFF340F0AAB3" modified="2014-02-19" version="1">MASSRRVVEREATARGLPVDDRPHRVVDGLAHAVGREVLVQPHPAVEQEAVLGVVEVGVAGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU25</accession>
    <name>V6DU25_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C462_01233</name>
        <name evidence="6" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="17"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="22543" checksum="77121DA2ED39B6F7" modified="2014-02-19" version="1">MPCLPRLELNKLKADVQTVFQSAVRRGTVITGSAGNDSGSLQGSGFTLPNSVPAAFTVSATSPADTLSFYSNFGTSDIDIAAPGGWYETTDRTLNASAEDGEIPFPQNGVLSTWPTDEESSVGLTGYDYISGTSMAAPQVAGLAALVRELDPDANASQVEQAIQKGAELANGKSDPEFGAGRINALNTVERLADGKGNGNSNGKANGKANGKAKGNGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU26</accession>
    <name>V6DU26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dihydrodipicolinate synthetase</fullName>
            <ecNumber evidence="1">4.2.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_08720</name>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.41" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076803.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="52406at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047448">
        <property type="term" value="F:5-dehydro-4-deoxyglucarate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="34368" checksum="B5AB1FE638BFBE23" modified="2014-02-19" version="1">MPTTAAQVKQRLRDVAVGVLTPFDKQRAIEYRKMEENARTLYDEGMRTFLAAANISEYHSLSRRERIESVETVVKAVPADACVLAGVGGSTADALELIEEYDRVGADAMMIMPPDHTYLHERGLLDYYRELSAATEAPLVPYVRGFDPSAEYLADLSRVDGVVGVKYALEDPVKLGEAIRAGDDDVIWVNGLAEPYAVSFWAEGVEGFTAGVSNFRPEVGRELFDALTEGDWERARELRDICLPYQRLRGERGQNNVLAGAISVPAVKKGLELAGLHGGEVREPIRPLPAEAADRAEAIYDELDGDIDRLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU27</accession>
    <name>V6DU27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11020</name>
        <name evidence="1" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16262" checksum="9F13869848F4BBD1" modified="2014-02-19" version="1">MTDISWTIRTLDNGILTVPGAIGSSLPTFGVGRTVSLQFLADSDGVAFDILREYARYSNESTTSTGTDIRGKPWYHQSIHPSAGFASTLVLIEPGTSVGDLQDWWAVVTGASIATTPVGTGRRVTLDLFVLAETAEYSERQFVVDEFEAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU28</accession>
    <name>V6DU28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5241" checksum="00B1673580A73A70" modified="2014-02-19" version="1">MCTSLRCHRKRGIQLVWMEIQVGANTSHTNSTLSPHNLYLDSNTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU29</accession>
    <name>V6DU29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="107" mass="11355" checksum="48824CE12D46BFB3" modified="2014-02-19" version="1">MSAPNGFEQFDAVGLGRLVGRDDAVEPXXXXXXXRTRGRSRGVRGRRPSTCPASPGSRRARRAARRGTRTRSGAPARASRPKSSAPGRFFHGSVASTTSRSASIVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU30</accession>
    <name>V6DU30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamyl-tRNA(Gln) amidotransferase subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gatE</name>
        <name evidence="6" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004414">
        <property type="entry name" value="GatE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF2">
        <property type="entry name" value="PTHR11659:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="5">
        <location>
            <begin position="2"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="7796" checksum="6F7366DF91EE7FEE" modified="2014-02-19" version="1">MSAAEAVEEAGLSGVSEEEVREAVVEVVERNADQINAEGMAAFSGLMGEAMGALRGKADGEVVSDVLREEIGKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU40</accession>
    <name>V6DU40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="7346" checksum="4100C943859BFB28" modified="2014-02-19" version="1">MRLRSDGTRRGSCRRRSRRLPNNLRFSRWGFGSLGNNVGFVVASDAGSIILQFSRRNRRQQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU41</accession>
    <name>V6DU41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinetochore-Ndc80 subunit Spc25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C469_13285</name>
        <name evidence="4" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076812.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="12724at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="3">
        <location>
            <begin position="11"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="334"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="642" mass="73637" checksum="4B16E34C18C94676" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU42</accession>
    <name>V6DU42_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_03319</name>
        <name evidence="3" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077260.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58046at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="4"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="225" mass="23914" checksum="1999687D0E5F623F" modified="2014-02-19" version="1">MTSALFVVSEEGYWAEECIEPLTTLESEGVDVTVATPSGSPPVVDERSLDPEAAGGEERVAKLREVDEEHPELNDPEPIAAVEADGHDAVVFPGGHGTVWDVNQDRHARQLLLDAVAGEESVALVVCHAVGILAFTREADGTPLVEGRSITGFPNEWEEDIVDDRDVMPDGRKLPYWVEDEVVLAGAAFDAELDADTSVTVDGDLITARGPGSSADAAATLLDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU43</accession>
    <name>V6DU43_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BppU_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_11075</name>
        <name evidence="2" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077239.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="129862at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018913">
        <property type="entry name" value="BppU_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10651">
        <property type="entry name" value="BppU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BppU_N" evidence="1">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="11389" checksum="1BE866FBA9762C53" modified="2014-02-19" version="1">MAETFSLAVGDTAPSIQAVLRDSVGDGVDLTDADVQFQMRQPRGGDVLIDKPADVIDATAGVARYNWNASDTNELGRYRAEFVVTYKSGAVETFPNVGAHDIVITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU44</accession>
    <name>V6DU44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_06780</name>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025098">
        <property type="entry name" value="DUF4013"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13197">
        <property type="entry name" value="DUF4013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="24646" checksum="10B84A4D04084DC2" modified="2014-02-19" version="1">MFRSGVLEDGLGYPVRGDWVGRIIIGGVLGLLSVLVIPTFAVFGYLVRVLERTVAGEEVPPEFDDWGDLLAKGVVATLIALAYSVIPVVAYGIFITVVAGIGSGIGGDIGALVGLTGALLALAFIPVLFLIYYAVPAALTAYAARGEVSAAFDVGLLKPTLFSVDYLLAVLMPIVVAIGVFVASVVLLVTVVGAVFVPFLQFYGQVAVFRMFGTAFADQSDRLQAKPTGGDGAAATSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU45</accession>
    <name>V6DU45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="7723" checksum="3637C476B35383AE" modified="2014-02-19" version="1">MALMLRERAHEVPVVQLLDVGPVDVCILERPQRGLAEQVAACALRVATETGEPDPGDAYVSHTRTMIDDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU46</accession>
    <name>V6DU46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4796" checksum="319810E159195780" modified="2014-02-19" version="1">MTFLCVVPTSTRSTSRWHLVTFTRGVMWVNHPDPVPEFGAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU47</accession>
    <name>V6DU47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="6007" checksum="F2107DCC923F8593" modified="2014-02-19" version="1">MHPSQYEYPPGLMPDAEPEYDCIHACGEVTIYEIDDLADTRIKSDVYMPVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU48</accession>
    <name>V6DU48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C450_00015</name>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="8002" checksum="0463F6C62E245CBC" modified="2014-02-19" version="1">MNAAATETVPLFEYLEFCSIENAVRERDHSVLTSFLRLLSANERMISRNYRYQNCERRGESCVRLIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU49</accession>
    <name>V6DU49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="238" mass="26167" checksum="0739E4AB17A769AD" modified="2014-02-19" version="1">MRRADDEVGLGFERLDGGLGSLRVAEHLPVLGVVRDVVKAGGAHPEDADGVAPDLDGRPALRAGDRLPFRREEVGDHPRELGGLEALARGVDAEVELVVPGTDGVRSHLVERLDHVLALELEAEDRRREVVAVPEEGRVRVLAAKLLDDGVVPRDVYRLVASVLEPAVEVRVVDERERAVVLRRHAARRAGSEGTDGYSARGRRQQATTRLIDDRLRTPVFRHTSVRRRDAIKHLHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV2</accession>
    <name>V6DXV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_09344</name>
        <name evidence="6" type="ORF">BN903_115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077668.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="107233at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="135" mass="14188" checksum="ADEA1B77A3A3C932" modified="2014-02-19" version="1">MSDDATDSTDDLNRGAPSQLGRVLLGVGLAAQASEDFRDMDDTVEYAESAGVPMPEVAAPFASGMMVVAGVGIALWRLPRVATGAAVAFLTVVTATMHDFWNANEDDASGERLAFFGNLAMLGGALVFLREAYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV3</accession>
    <name>V6DXV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000048">
        <property type="protein sequence ID" value="CDK41164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5083" checksum="5C9BF24F0263CACC" modified="2014-02-19" version="1">MTFMRGGSLRVTSFFCWSVHASRSDAPDERRVNIAVPTSRSAVPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV4</accession>
    <name>V6DXV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="9677" checksum="3C4AE13F98A0F534" modified="2014-02-19" version="1">MLIGTNRSEAPAARRADARCAPRSVASLPRCGAYVVIRTLRVLIGSRELRSRERLCPPRGCPFESRPATAQHLMPPQPRQSPSLRSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV5</accession>
    <name>V6DXV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome b subunit of nitric oxide reductase</fullName>
            <ecNumber evidence="3">1.7.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_08255</name>
        <name evidence="3" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.5" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000048">
        <property type="protein sequence ID" value="CDK41162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016966">
        <property type="term" value="F:nitric oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="2">
        <location>
            <begin position="185"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="472" mass="52403" checksum="CBCBC374795E9FF5" modified="2014-02-19" version="1">MGGLLAHFYIERAGFFGIEQIFGVHILQLLPFSIAKTWHIDLGILWIASTWLGAGLFLPPLLTGHEPKRQGTYVNVLLGALVTVVVGGMAGIWLGANGYLPGELWWLLGNEGLEYLEVGKVWQFGLLAGFVLWAVLAIRGLKPLLDREPAYGLAHMILYAGGSITLLFVAGFMFTPSTNIAVTEFWRWWVVHMWVEGAFEFFIVAIIGLTLVSMNLLSRRSAEKAVMLQALLVMGTGVIGVSHHYWWIGMPDYWVPIGSVFSTLELLPLIFILYEAIGQYRAMTETSGFPYKLPFMFIVASGIWNFVGAGVLGFFINLPLINYYEHGTYLTVGHAHAAMFGAFGFLALGMVAYMLQLSIDPDRWDGSWLRASFWCWNVGLALMVGISLLPVGFLQLDVAFTEGYAAARSLEFYNRDLVQTLFWARLPGDTLIIIGTAIYMADLIRKRFVLRASEDDPSVDDMAVAEGIVGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV7</accession>
    <name>V6DXV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12436" checksum="33B400BEF36CEE70" modified="2014-02-19" version="1">MAFSHLCREMNADRERDRSVGAGGLVVAERRGALGVGYFDTAAFELLDELGLAEPRLRGRLRQGQGSRTVQRQRTRQPVRGHTLSSRVRDYEGYYFIKGPDTPYTIYIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXX0</accession>
    <name>V6DXX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4058" checksum="C1C40FA2DE63DA09" modified="2014-02-19" version="1">MPNAAAAARSALRNPESLRSVAILVSAGGDGTERSSQSSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXX4</accession>
    <name>V6DXX4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminotransferase class V</fullName>
            <ecNumber evidence="6">2.6.1.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_11545</name>
        <name evidence="6" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077753.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20398at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="5">
        <location>
            <begin position="31"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="369" mass="41694" checksum="F5F49031A15FA8D7" modified="2014-02-19" version="1">MTKKREYRDDYDDKTLYIPGPTEVREDVIEAMTESTFGHRMDRMTDLYTTIVEDTKEFLGTDNEVVILTGSGTEFWEATTLNLVDEHVLVPTCGAFSERYANVAERLGKDVTRLEYEWGEAVKPEDVREAIESADGHYDMVAGVMNESSTGVRNPIEEIGDVLKEYPDTYFAVDAVSSLGGDYVDIDAHGIDAIFASTQKAFAMPPGLAVCVVSDDAYDRETEKGDSSWYGGFRRTIDYYDRKGQTHSTPAIPIMLAYRKQMKHMLDEGHRARDERHREMTEYVHDWADEHFAMFPEEGYESQTVACIENTRGIDVAATIEEVSEEYDMAFSNGYGDIGEETFRIGHMGEHTVESVKELTDAIEDVADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXX7</accession>
    <name>V6DXX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_11033</name>
        <name evidence="3" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="12232" checksum="8DE33B94641B9545" modified="2014-02-19" version="1">MVPRSHIEPMDTPDRPLVSAVVITCDRPEKLVGALASLRRQTYPNLELVVVDGSREPVESSSSARLRSEYGPVTPSRGDRSRTQEVRWLGHRTHLRAASLSTHPDIYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXX8</accession>
    <name>V6DXX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6217" checksum="9CF70008AD4D76FE" modified="2014-02-19" version="1">MSDLREMLFAIEITLVGITAAVLSVLYNSFLLSVIAGGTTIFGLLGAIIVRRRARRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXX9</accession>
    <name>V6DXX9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="3">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_07079</name>
        <name evidence="3" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077699.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121393at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="DNA-dir_RNA_pol_M/15kDasu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOL9" evidence="2">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="104" mass="11384" checksum="CF7E5D0567FB78B4" modified="2014-02-19" version="1">MKFCDKCGSMMHTDGDRWVCRSCENEEPRDSGAEAAMATRDGQRDDGAPAVADATQDSAETVQEPCPAADCDSDRATSEMMPKPGGSYEVRLFTCVECGHKWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXY0</accession>
    <name>V6DXY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase AglI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C464_10983</name>
        <name evidence="3" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="58"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="357" mass="38718" checksum="5312BAD1FAFBDBA0" modified="2014-02-19" version="1">MSAHRSGGRTAGTAPITMCVVADTLGVTPQPSPSTADRRPSDAGDTADAEGDELPFVSVVIPVYNDPDGIEATLDSLRRQSFPADRYEVIVADNGSTDETRDVVREFLGAFDGLRLIVEDDVQGSYAARNAGIRATTGDVIAFVDADMVVDPGWIEAVARRMARTDAEYLACDVRLFTTGDEGAVAEYNRREDLHVERLVDELSFAPTCCLVVRRALLAEVGGFDPRLRSGGDMEFGNRVAASGRDLEYAADVVMYHPTRTTLGALLGKSRRVGRGKTQLRRHYPDRYGSPVLSALNPAAFLPPRPSFMRRAVRGWAELSARKKLVFLVVSYVESLAKAYGQLLELASPTETSADAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXY3</accession>
    <name>V6DXY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5576" checksum="B2E7260D2B4D387E" modified="2014-02-19" version="1">MCASFECFSSDPDFDAPLKFLGAVTVAIGDLWTEKGCHGNLTTNFILYSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXY4</accession>
    <name>V6DXY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="3">5.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisA</name>
        <name evidence="3" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="172" mass="17518" checksum="67C196E52CA00FB4" modified="2014-02-19" version="1">MEYVPEEVGLQLGGGIRTAEGARDLLDLGLDRVILGTAAVETPEIVAVIDETHPGSVVVSLDAKDGEVVVSGWTEGTGLDPAEAAARYEELGAGAILFTNVDVEGQLAGINREAVESVVEAVDIPVIASGGVASIDDVVALKAAGAAAVVVGTALYEGEFTLREAQYAADEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXY5</accession>
    <name>V6DXY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegT/DnrJ/EryC1/StrS aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.87</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_10953</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.87" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099620">
        <property type="term" value="F:UDP-4-amino-4-deoxy-L-arabinose aminotransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="331" mass="35239" checksum="8596D1DDE96F5EFF" modified="2014-02-19" version="1">MLTGGRLADGPVVRTFEREFADYCGVERGVATANGTAALQTALEAVGIGEGDAVVTTPFSFVASANAVRLCGARPVFADIDAATYTLDPEAVEAAVAENDDVAAILPVHLYGLPAEMGRLTEIAEEHDLALIEDAAQAHGATYEGTNVGAFGDAGCFSFYPTKNMTTGEGGMVVTDDQGVADRAARFVNHGRADAAAHGYDHVSVGHNLRLTSLAAAIGVEQLRKLPAYNARRRENAARLSAALSDVPELVLPTEPPERRHVYHQYTVRCPDRAALRDHLDERGVDTAVYYPTLIPDQPAYDGYEASVPTARRIADEVVSLPIHPGSSTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXY7</accession>
    <name>V6DXY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_07039</name>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Succ_DH_flav_C" evidence="1">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15521" checksum="5B29D43514076CC5" modified="2014-02-19" version="1">MDAALADLRELMWDHAGILRDEASLREGLDRLADVRERVADLRVGSVTSESFEFAVDLGFMTVAAEAVLRGALEREESRGAHYRTDFPDVDADWRRNVYFEAADVGGMRLRTEPVDEPSEAVQAALDEGHELDYHQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXY9</accession>
    <name>V6DXY9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11485</name>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077705.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76892at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="195" mass="20944" checksum="C8A457695F56D1A6" modified="2014-02-19" version="1">MDEIAIRDPRPGDAEPLEALITSHFSEGSSYGVDLGLDDPMYRVLVAVEAGSDGGASTDRDDAILGVMALRELSDAAAVADEMYFFDDPDLLPAAELYGHLEMGYVSEAATGRGIGSRLLERLHAIGAERGVDLFVADSWYHGGDDTPERLFDGHDYETIHRDPIDRPAAECPKCEGECVCEGALAVRRVEGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXZ4</accession>
    <name>V6DXZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_07771</name>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6453" checksum="45EA849D33B97BFC" modified="2014-02-19" version="1">MGQNETAHAPTDDVSGDTEEFDPIGTLTLIGIYFAILVLSWVYIYYIEFLGRDLIVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY72</accession>
    <name>V6DY72_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_01684</name>
        <name evidence="2" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zinc_ribbon_2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5880" checksum="F16A8B2843C98DA9" modified="2014-02-19" version="1">MLSKQFIQQIVRPEPLSTTHHECRHCGYSVEEDVDECPQCGSREIAAYDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY74</accession>
    <name>V6DY74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RimK domain protein ATP-grasp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C465_08346</name>
        <name evidence="4" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="3">
        <location>
            <begin position="97"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="161" mass="17144" checksum="0DE91EF403A40945" modified="2014-02-19" version="1">MIRLAMTTDAETFERVREPLGERGIEVGHVRAKERSLRVSSGGGERAEPADEFDGFDVGLVYPTRLMEGAVVDERLGVPWVNGRDAVVTSRNKAGVLAALDAAGLPTPGTTLVSNPVDESVVVDAVNDFSYPVVVKPNSATRGWGSRPRATSTRFSASSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY75</accession>
    <name>V6DY75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C452_14055</name>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="23967" checksum="3620D7D927BCABD4" modified="2014-02-19" version="1">MELNKTDQLILAKLREGRCTPRYLSDELDRNQSYVSQRLRHLQDEGHVDRVHRGLYRSAAVDSSHVSAEDLVESHEPAELVSSVANCSQNDATTNEVFPKKSSLSIELGTDDIPTVVTRVCQSGTSEEQQVLESIFRDILWTLIQDGQITDKELRAEVNRLTDIDVVGFRDIHQYKTKITNRLTSHPQISLKRNLPSQEIIYTGESPVLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY77</accession>
    <name>V6DY77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C457_15902</name>
        <name evidence="9" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077768.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45576at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="27"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="283"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="382" mass="39979" checksum="F5E169D750D5578F" modified="2014-02-19" version="1">MGLVSVLRRFPSVLMAWRNLGRNRTRTALAVLGIVIGVIAIASLGMAGVALEQQATASLGGLTDEASVSPGDDIETDGITDQQVDTIQDIASGTTVIPQKTNRTELTARNGEAANVQVTGVTNAAPLYDIAVGDEPSRLETGALISESTTRTLGLEMGDPIEYEGQIFRVRGFIASDSGFGPDGGGELVLPVSALNEQEYYTTVTIIAEDGDSATEAANAIEDHFNDEDDEILSVTTYGNVQENITSFTDTLELALLGIGSISLFVASVAILNVMLMSTIERRGEIGVLRAVGVRRGEVLRMILTEAAFLGAVGGIVGAAGSLAVGLVIFHLLVGDPVLALAWSSSKYLLYGFVFALVASTLSGIYPAWKAANESPVDALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY92</accession>
    <name>V6DY92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">IS1341-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C465_13865</name>
        <name evidence="7" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="13"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="147"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="206" mass="23410" checksum="3821F9F662B99F01" modified="2014-02-19" version="1">MKVVWTGEKWELHFVCKVEIDVSDSPGEQTVGIDLGINNFAALAYEDGHSELYPLNCLKQDDYYFSKQLAQCNDSNSEQATRLNQKRSGRRTHYFHTLSKHIVQRCVEEDVGTIVIGDLSGIRENDETDESKDWGIHGNLDLHSWAFDRFTKLLTYKAEMEDITVEEVSERDTSKSCSCCGRKRDATVLNVDCTCATTAGRRQTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY94</accession>
    <name>V6DY94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5556" checksum="19E811B2AE43F72B" modified="2014-02-19" version="1">MTADPYFNRLSRRPISLHKRQVNPRDTFAEALDLRHRHSEVERLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY96</accession>
    <name>V6DY96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018243">
        <property type="entry name" value="Neuromodulin_palmitoyl_site"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00412">
        <property type="entry name" value="NEUROMODULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5208" checksum="DFE0B368CDB78040" modified="2014-02-19" version="1">MLCCLRRDTLLCPHLVRPFVINQRYIEGATGLGSEYSQPASHFRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY97</accession>
    <name>V6DY97_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L32e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_12455</name>
        <name evidence="7" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078226.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89813at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_L32e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_L32e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_L32e_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="PTHR23413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="SSF52042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="HhH1" evidence="6">
        <location>
            <begin position="3"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="54"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="88"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="236" mass="26218" checksum="813B1D4BAF5014EB" modified="2014-02-19" version="1">MADELEDISGVGPSKADALREAGYETVEDVKAASQSELSEVDGVGNALAARIKADVGGLEVDEEADAEIEDETDEEEAVEETDESETVETELRPRGHADKTPELDDETARALAQKHREGKPQFNRQDYHKKKRIPTSWRKPRGGLSKQRRRMKSKGPVVEAGFRSPTASRDLHPSGFEEVRVHNTDDLEGVDGDTQAVRIASKVGGRKRELIEDEAEEREIRVLNPTYVEVEVDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPB4</accession>
    <name>V6DPB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075947.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="143420at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="11763" checksum="10450E1B4753BE5A" modified="2014-02-19" version="1">MPATETEYGRGGPYPKDGERFDPINGTPPNGWDLDAHLVGGGADTPRRETALWSHPAGGTIRVVRLPNANEKPYALVVTATGESRRGKREAIFDQARETMGRHHSTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPB5</accession>
    <name>V6DPB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4715" checksum="8D140E78BC804FBB" modified="2014-02-19" version="1">MTGPNHREIDFCLLPWTVATVSLSWYLPCFLVVISREGDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPC8</accession>
    <name>V6DPC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075955.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="19382" checksum="31267C9E4779290A" modified="2014-02-19" version="1">MNDSFKELLHTSPTCPFCGCAPVDARLIGLNAVVCEPCSENIYFHSAAYATIFADGTSIELWDYPAQAQAWRQAESTNAVFLEPNYTTSELTDSQQTAIAAFVTNTHRDVLSRRPLADIESKYLKTIRRGQTYGDSGSKEAQLKQSIDGPVILTSQHLYAPDPAALTAAQETQATLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPD4</accession>
    <name>V6DPD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="105" mass="11936" checksum="D908ED243E9E3060" modified="2014-02-19" version="1">MTEFETTLKNTDHLTEETAQELREQLLEALEYDNSWTLDADSAEPCVDETGDWHLFTLSHDDSHDRCVTVLIHAITLTIQTYLEPAGVYTEPSQSIEHIQTALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPD9</accession>
    <name>V6DPD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="255" mass="27308" checksum="319ED59A85ED2E87" modified="2014-02-19" version="1">MDDTPLFTSDRRTRDDSSWSGGDWEAGSASNVDIVDGGLVPVVTNLSGEIGDQFATSFETASVGSIPDGWTNAIHGSNGGAGVDDGRAADGSRSLKNRDPNTGSPSHSHISTAAYSPTGDHAFEFDYYVHGNKNNSGSADSFSFTNLNQVYDATSHNGIQRGFSVNAVNNGSWIAAYDGDGDGGGNNVNLEPAIFDRWVTLRFVVEYSQNRYSVFIDGEQYGPFGFQYNGTSADFPVFANSVDNYTGWIDNFRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPE2</accession>
    <name>V6DPE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075911.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="123" mass="13308" checksum="49CB95A75A424385" modified="2014-02-19" version="1">MSTKPSGPVGLKYGTGPQETARTAHEDKTLAATIRYDDEKEIGAGSDLVLQDANGEPFGTATVVHCEMLLTMCAFGPVRAYGAEYGLSTIPELLLTLNRYYNDTVTLETPVKVIIYEPHDITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPE4</accession>
    <name>V6DPE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075960.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="17757" checksum="C58248E0C3743DD1" modified="2014-02-19" version="1">MSDTSDDTDNTPDGFRAVDPEPGRTSPIGEPVELIYEPEGCVLDFEGSDYTCTVVVLQTPSLYLTELSIETEAGDTKFEKGYAANEARALAEQLLGGNAPKLTQFVGGVQNAETLGQYLKYGASMAGTLAIGEVAGDDTINAFKEGKITPEEFLHEYGRNVDKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPE5</accession>
    <name>V6DPE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075961.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="10008" checksum="E4D548A4F7DE621C" modified="2014-02-19" version="1">MEEYVRRVERWLPDSEMVELHNGIAVVRTVEGDVLETKQTKNGLYHQFTIANDPCWLDLLAPTVTCDECLHLGDLSVEYDDGFLVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPE7</accession>
    <name>V6DPE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075916.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15670" checksum="5BAB154BBA14F2BF" modified="2014-02-19" version="1">MIPCFPDHIKNGECPECDIVHSEYSSFPDEPITVNECNELERDAGIDMILPIFRVEDTDEQGYYVQVVPAVVAIEENIVRVLWCNPSSDDDWIVVSEHETPMPYELARELRNTLRESAQLERTVAGHNVIEEPLITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPG1</accession>
    <name>V6DPG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MBGDF03_00942</name>
        <name evidence="2" type="ORF">BN903_251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075929.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112053at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="158" mass="17926" checksum="CD884B282A58A6B4" modified="2014-02-19" version="1">MSDQTVVGITACSKSKSVDDDFQGKIEAQHLYDSWLFDSRRDALKANCDEWAIFSGKFGYVEPDEKLPWYDQQISELPEDEQWELAEEVADNVTHTDKVLILMGRDYAEKLKDALDASVTIWDPLEGVQLFDQRGKLKELADGTDPTGQTTFAELDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPG5</accession>
    <name>V6DPG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C474_12511</name>
        <name evidence="3" type="ORF">BN903_256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="20081" checksum="5201B4681B45D4E7" modified="2014-02-19" version="1">MSDENTNSSGEVDSDDAAESEEVVEPEDGQPSLVLVLAGVAGFGILIGTGALIGVEAYTVDWDGEVELVSEGETVETFSVVHADTQSEKESGLGGVSELEAGTGMLFLHDEMRTFTYAMPRMEFGIDILFIDDSCVIQAVHEADAPTGNETGVEPHHQYRGVGKYVLEVPKGAASGVVEPGDSVRIDGGCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPG6</accession>
    <name>V6DPG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075982.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="19661" checksum="4CAA69E473841CDB" modified="2014-02-19" version="1">MNSETHADDPADVATALRNIKRHTVGYGERYPQPDTDHFVTEDTNANGGVHHQNQSNEYGYDLTSFGSGRQGVRNFVAVLDAGNLDPVDDYYRVFRDMGRGVDIDYRDRFVFVWANEGAMVVCSNNPITGEANGPNINNEQGGAGYVGVAGDTPAVDDIIEAIDQHGTTKSGRREGSLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPG7</accession>
    <name>V6DPG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="17827" checksum="902A1FB1AB02A66D" modified="2014-02-19" version="1">MQMEDAEAEAETKTKPKGGRDRVSHKQLERCSCGPSQVESVSYGLPDDSFISLTRCLSCEGLTDWTIRKHETKFNRDSDEPQETPSNDPEPKTDENTTDAPDLGGVSGFISFLGRETIALVIVGIGVTIFAVQWGFTMLTGAIALLSFLVILPLLYFTNSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ2</accession>
    <name>V6DTJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen</fullName>
            <ecNumber evidence="5">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_01311</name>
        <name evidence="5" type="ORF">BN903_144</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076600.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98508at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="2"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK38850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="156" mass="17065" checksum="B9040C450A86A915" modified="2014-02-19" version="1">MPHVGDDAPDFTGSLVDGDIAPFELADHLGDEPVVLAFFPAAFSNTCTDEMEALRDEFDRDDCTLFGVSTDLPHALAAYRTQYELPFALVGDPDHRAIEAYDVIEDFEHYGVETVAQRAVFVIDADGTVTYRWLADNAGQEPDYDALDEAVADATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ5</accession>
    <name>V6DTJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4937" checksum="DFA1FAFABB79CFD6" modified="2014-02-19" version="1">MGPESGTREVRSISEDMSSRSIKMVSKMIEYYSDTSNDLFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ6</accession>
    <name>V6DTJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5972" checksum="FF79DFC5C01654C7" modified="2014-02-19" version="1">MIFVDLRDSALFRRGVNRVLQSLFNERDRVESYSRSDSVHLTEQLTTAVGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ7</accession>
    <name>V6DTJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C463_07312</name>
        <name evidence="3" type="ORF">BN903_149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="15711" checksum="4C54E8B4C8907350" modified="2014-02-19" version="1">MSGERGTRPRSGTQSGRWTLDSTDRAQTVLDFVVGMSVFLVAVGFTFAFVPSLLEPYAVGEGATVIVAERGAARLAESSLAXXXXXXXVVGPDASCSTVRPSCDRGTPRGDADAREPRGRDGRRRRGRRDLRGRRAGLGRRGRARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ9</accession>
    <name>V6DTJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14630" checksum="AD9F06E1D6C5CF76" modified="2014-02-19" version="1">MMNRTTLIALLSLLATVFLIGIPTAAGFYPPLFAGFAESLPIEFILTWMLRFGILTLGFTLGWYLRGDSEVTDAERVDTIEGCIQTNDIAWKGTAALSRGKVVDTDVEYKQICPKCQTPMKDDTFEASAQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTL1</accession>
    <name>V6DTL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4682" checksum="7D773524435F2C2F" modified="2014-02-19" version="1">MDTDSASVSVLVRSRDRRGGSLVGRTDAAARLRRIDAASRSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTL3</accession>
    <name>V6DTL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C472_08124</name>
        <name evidence="9" type="ORF">BN903_101</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="73"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="146"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="7">
        <location>
            <begin position="218"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="399"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="117"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="450" mass="47747" checksum="12D905262C2F665D" modified="2014-02-19" version="1">MDKGPIERIRSSYGTRLALSLVAVTGVSVAYGAIVYLRATELGPAGAEVRSGLVGMSLLTVIGLALIGVTVGSNTVIALRQLTGKAERMADGDLTVELESGRSDEIGRLFGAFDEMRGSLRAEIDDAERAREEAEQARREADARAETVERKASEYETAMRALADGDLTRRVEPASDNEAMARVGTAFNEMAEELEGTVASVATVAEDTADVAGRVDDRTDSLRATTGTVSEAVTEIAEGARTQRDDLRAATDEAESLASSAEEVASTVTDVAETAEHAAAVGEEGREAAEEALAEMDAVEETTAETTAEVEALAAEVEEIGQVVDTISEIAEQTNLLALNASIEAARSGADGAGFAVVAEEVKSLAEETQESAGEIEARIHAVQERAETGAAAMARTEERXXXXXXXSTRRTPRRRSSRPARPSRTRATTERNPRSRFELPDFVEISNSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTL4</accession>
    <name>V6DTL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/Gluconolaconase/LRE domain protein</fullName>
            <ecNumber evidence="2">3.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C461_05522</name>
        <name evidence="2" type="ORF">BN903_169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076625.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="52063at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="15"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="289" mass="30840" checksum="B9F46903186707FE" modified="2014-02-19" version="1">MARTERVADARAHTGEGPLWHPAERRLYWVDIPAGVLYRYDPETGENAVAYETDGVPIGGYTIESDGALLLFTHGAVERFVPGESDTETVLTVDAAGRFNDVIADPEGRVFAGTMPTEGTLGDLYRIDTDGSARVVVEGLDIPNGMGFSGDGTTFYLTESEARRIDAFDYDYVTGEIANRREFVETPPGDGVPDGLTVDAEDHLWSARWDGGRAVRYDPSGRAVAAIGLPARKVASVTFAGPSCDALYLTTALAGGDREREGDGAGALFRATGLPASGRAEFRSRIAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTL5</accession>
    <name>V6DTL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor CBF/NF-Y/histone domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_07999</name>
        <name evidence="6" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal histone HMF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077144.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108727at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBFD_NFYB_HMF" evidence="5">
        <location>
            <begin position="4"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="CBFD_NFYB_HMF" evidence="5">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="15619" checksum="D895A970FCA8F3A7" modified="2014-02-19" version="1">MSVELPFAPVDGIIRRNAGELRVSADAAEELARRIQSHGAELAVDAAERATADGRKTLMAADFGVEQVVSREDLTLPVAPIDRIARLRIDDRYRVGVDARVALADILEDYANNVASAAATLARHADRRTVQAEDIETYFALFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTL6</accession>
    <name>V6DTL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5939" checksum="4ADDE811452CFE77" modified="2014-02-19" version="1">MERSHGSLSHGVGSDEVDDTKRWRAPPRPHRGRGASREGVGRRSNAEATDEAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTL8</accession>
    <name>V6DTL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11284</name>
        <name evidence="2" type="ORF">BN903_174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076627.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93794at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043828">
        <property type="entry name" value="DUF5805"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19121">
        <property type="entry name" value="DUF5805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13955" checksum="8B3CBF78BF5079DF" modified="2014-02-19" version="1">MGGDRQSVKTYVPAEQKDVWRNHADELDMSLSEFVRTMIQAGRKGFAPTESSGDEEPASDPSDPGGRDLETRVHAVLESGPRSWDELVEAVIGDVEDELEATLDDLQDQNRVRYSGRDGGYVLTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM0</accession>
    <name>V6DTM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05954</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077136.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63960at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="17"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="217" mass="24862" checksum="E41FE2B37C22C630" modified="2014-02-19" version="1">MATDSDAASGTDEPDAITVYSDYVCPFCYLGRNVLTRFLEDRDNDIDFDWHPFDLRAGKRSPDGSIDHDADDGKDDDYYEQARENVRRLQEKYDIDMAQELRTDVDSWNAQQASLYVREEHPGKWRDFDEALFDALWTEGHDIGDLEVIENLAEDIGLDPVEIREAIKDEEWSKRLENAHREAKQKGVTGVPTFEYGGHAARGAVPPEHLERLVEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM2</accession>
    <name>V6DTM2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate 5-kinase</fullName>
            <ecNumber evidence="7">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-glutamyl kinase</fullName>
            <shortName evidence="7">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">proB</name>
        <name evidence="9" type="ORF">BN903_179</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="167"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="27826" checksum="6427CA6AB561D334" modified="2014-02-19" version="1">MIVKAGTNSLTDDESRLDRVKLDKLVADVMDLRERGTEVVLVSSGAVGAGTGRLDAGPESRDDVDSIVENQALSTVGQGLLIRHYTQSFERFDQDVAQILVTGTDLDAPDRFDNFTNTVETLLSWGVVPVVNENDAVATDELRIGDNDMLSASVALGLDADLLVTLTDVDGVYTENPKRDADAALIEAVDDGYDRLREIVGDGTETDFGGIRTKVEGAHDVSRHGIPAIIAGSAERDVLARIAAGKPTGTLFVPKTGDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM3</accession>
    <name>V6DTM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="5154" checksum="72FE76E855886D6D" modified="2014-02-19" version="1">MIVSAVRNNNFHNVNHRPGPRRLRRIVRTPFRWPVTASPTRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM4</accession>
    <name>V6DTM4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpsG</name>
        <name evidence="5" type="synonym">rps7</name>
        <name evidence="10" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5 7">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077151.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80498at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_A">
        <property type="entry name" value="Ribosomal_S7_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_S5/S7_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026018">
        <property type="entry name" value="Ribosomal_S7_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="71"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK39532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="217" mass="23672" checksum="8EEB5F145C11A2B1" modified="2014-02-19" version="1">MSGEETEAASGEDVAADEPDPDAPASSEAANENAKLFGVWDVTEIAYEDPSTKRYMTVTPIAHTMGRHASKQFKKSEISLVERLINRLMQTDENTGKKQQATRIVRDAFDIVHERTEENPVQILVTAVENAAPREETVRLKYGGISVPKAVDVAPQRRVDQALLFISDGVASATYKSTTSAAEALANELISAADYDVEASYSISQKEERERVAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM5</accession>
    <name>V6DTM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_07959</name>
        <name evidence="1" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077140.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117927at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15694" checksum="0367F29C4E41BB3D" modified="2014-02-19" version="1">MPRSTTVIEDTDVQTIEWDDEVGVPVFTWNDYVAGETFRENARRWEEFVAERGADTYIVNTEGVTAHDDADKRWLAEEWVPNLIDEGVRRGAGVYPDSAIASMEMEEVEEQLSALDPDFEFRAFASNEKAKEWLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM6</accession>
    <name>V6DTM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5645" checksum="2E083CADC0C571FC" modified="2014-02-19" version="1">MSVICHIGTNSAPTSSAAAASGSARRISVSRASDERMALFLRFDDEPRAHLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM7</accession>
    <name>V6DTM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain alpha-keto acid dehydrogenase subunit E2</fullName>
            <ecNumber evidence="2">2.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05674</name>
        <name evidence="2" type="ORF">BN903_116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="2-oxoacid_dh" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="177" mass="19298" checksum="D06B9F2C8976467D" modified="2014-02-19" version="1">MKLTYMPFVMKAIVAGLKRHPYLNSELREDDEEIVLKGDYNLGIAVATDAGLMVPVVENVDEKGLFELAEEVNDLAARARERKLKPAEMKGGTFTITNFGAIGGEYATPIINYPETAILGLGAIEERPVVREGEVVPAPTLPLSLSIDHRVVDGAIAAEFANTVMEHLENPLLLLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM8</accession>
    <name>V6DTM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="9999" checksum="04A3A3D78833CF9F" modified="2014-02-19" version="1">MLLSRLLSTGDLAIDPPDCGGARLRAADRRRANTREVAGGSAAGCQRIFDSRWSRPTGATRREADEAGASAVVFAPLAAIPPLIASSPSKYPTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTM9</accession>
    <name>V6DTM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="7082" checksum="4B6275EE514FB9CB" modified="2014-02-19" version="1">MIRTHEKRLIRFRYSVNSRPAGTHRRDEPMTVRDPIPTFAPRRSVGRRIRGAVTARLGAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN4</accession>
    <name>V6DTN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="69" mass="8156" checksum="6078687E5E7F0DE0" modified="2014-02-19" version="1">MLFRAWCVRKRPDGVLRERRSRERRARPDGDLNSERRSASLRSAAATFLLKSPWRFFQYVLLATLAALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTN5</accession>
    <name>V6DTN5_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">BN903_194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
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        <lineage>
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            <taxon>Halobacteria</taxon>
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            <taxon>Halorubrum</taxon>
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    <reference evidence="1 2" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5482" checksum="6120082C20C5BBCE" modified="2014-02-19" version="1">MSFSSVDHDYRCAPFFWPRNRNDTAGRLKPPITLTSGVAWYHVAHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU00</accession>
    <name>V6DU00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="80" mass="8697" checksum="75C319C52EE0A228" modified="2014-02-19" version="1">MRGGRGRSRGQSSREPIRTLRVLMTTQAPQGESRALSRHHEMPESSQTTRACAHLAAGASVVVSISDLQARLNDQITLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU01</accession>
    <name>V6DU01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5119" checksum="B6D58051A69231C7" modified="2014-02-19" version="1">MVTVKGLFIRPRHRRTSSGRIARTRPDEGGDRVPPGVGGTVIYSRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU02</accession>
    <name>V6DU02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="4846" checksum="B010AFEA3882D65E" modified="2014-02-19" version="1">MTVETEATEATEATAVTEATEATAVTEATEATAVTEAMEATAVTLPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU03</accession>
    <name>V6DU03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11110</name>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077232.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="145" mass="16089" checksum="99C79D69827D4CFF" modified="2014-02-19" version="1">MANGSRGAPEGNDNAVSHGLFQSRENLRNNLSDREERLLVDVAVDLIERFPDEADVGAYERGAIENIALDTIKRMRANEYILENNFIDETEKSNRANQVYSRIMSDTTAELEKLGLLKEGPALKDAEASEDWMAAISDATDRAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU05</accession>
    <name>V6DU05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5416" checksum="F3E61CE69502FD4C" modified="2014-02-19" version="1">MIERFDCSKIKEQRQRKQRSLLVTNKAWAGETVAVSRWDDRRVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU06</accession>
    <name>V6DU06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_03304</name>
        <name evidence="1" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077257.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118195at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="67" mass="7267" checksum="1B3C0938091C41D9" modified="2014-02-19" version="1">MYVPDDPPANCPACGDPYDSVSRHADGFVANLLDNDRYQRVCFTPVSDAGGPALDCYHHTHEQAGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU07</accession>
    <name>V6DU07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Halar_0123</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="3"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="13254" checksum="E1220451F100391E" modified="2014-02-19" version="1">MFGRHGTDPAAAFLAGLREKHDLSDATFLVDQFGYRTALSRLDLNGQVDYTDRNLIEKWFHTLKMRIDRFHHSWVGSRASVREWLEQFVHYYNHQRPHQSLNDRTPAEEVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU08</accession>
    <name>V6DU08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8426" checksum="AAAB6FA14F7A3B38" modified="2014-02-19" version="1">MPNILFITPLMPLIWTDDDGFVTRIHYRPSMVDDANRQDSEYVSSIPSSPGDLSENEARKNLYYSDELGIRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU09</accession>
    <name>V6DU09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6772" checksum="0806744D27E192F1" modified="2014-02-19" version="1">MGAEEAVEKNAYAGSHTNYSLYVDEPEPMPEPTGDIPTKDVDYTVIRNCPVYGAEIPILWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR6</accession>
    <name>V6DXR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C464_06623</name>
        <name evidence="4" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000036">
        <property type="protein sequence ID" value="CDK41122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="257"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="333" mass="36510" checksum="AB2B15F4EBCC5303" modified="2014-02-19" version="1">MNGPGRWRSWERWLGGESRELLLDRGECVECCNSACRSGGSVEVFITRGLEGVTDRHGHHTDDCAVADINGSRRSGTRLNLDRLDSRMREVTFRIYHAGEPECEVSANHPEVRYRSVSSMTGSGPERKRIAELTGPPAEIEAFVEEFREFDLIVSAEPLAPIEGTHAYVALTIDVAAADWEGIGDRFSRMGIHYRTGTTISGGVERWTAYLEDGDDLSAVMRELERGGNEVELARNVELASIERSPQLPASGLLDDLTDRQREVLATAIAAGYYEHGGGVGVEEVAAELGLGSTTVWEHLSRAESAVMNALFDRFAEGEPVTAVREADRLDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR7</accession>
    <name>V6DXR7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2249 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_09119</name>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077648.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116838at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018720">
        <property type="entry name" value="DUF2249"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10006">
        <property type="entry name" value="DUF2249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2249" evidence="1">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="78" mass="8615" checksum="091976558C1D9F37" modified="2014-02-19" version="1">MSADPFDDADERLDAREIDGEPFGDIMAALDGLDDGESLLLVNSFEPVPLYDVLAERGFTHETANPAEDEWFVEITPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR8</accession>
    <name>V6DXR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000037">
        <property type="protein sequence ID" value="CDK41124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7179" checksum="7C2FC74768E96449" modified="2014-02-19" version="1">MTPQRGHGTANATSIANVGIHTRSLRERIMCDKSVSVDTKNYRIDSKMRIGEKFSSIAVDGGAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR9</accession>
    <name>V6DXR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000037">
        <property type="protein sequence ID" value="CDK41127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8560" checksum="9954C17DBE9E6A1B" modified="2014-02-19" version="1">MRTDGDRTRTKPVVRSVVFRFEKRRDSVEHVRTDRTRGYSVELSEEGTPDAEKSRVGPADWSPLTLRPSRRSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT0</accession>
    <name>V6DXT0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase and fumarate reductase iron-sulfur protein</fullName>
            <ecNumber evidence="2">1.3.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02669</name>
        <name evidence="2" type="ORF">BN903_95</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="209" mass="24185" checksum="B2E4070AB5F3E7BD" modified="2014-02-19" version="1">MTVLDALMYARDTYDSSLTFRHSCRQAVCGSDAMFVNGGQKLACKTQISDLEQPVRVEPLPHAEVTKDLVVDMEHFYDQMEAVEPYFQTNEFPDGELEEQRQDRENREKIKMSTRCIWCGACMSSCNIAAGDNEYLGPAAINKAYRFAMDEREGEEIKQKRLEIIEQEHGVWRCQTQFSCTEVCPKDIPLTEHIQELKREAVKNNLKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT1</accession>
    <name>V6DXT1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ferredoxin_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15419</name>
        <name evidence="3" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000041">
        <property type="protein sequence ID" value="CDK41139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078483.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000041.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121416at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031604">
        <property type="entry name" value="Ferredoxin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16947">
        <property type="entry name" value="Ferredoxin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferredoxin_N" evidence="2">
        <location>
            <begin position="12"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9441" checksum="5B795BF3E66BB1CA" modified="2014-02-19" version="1">MHRDHEAPPDIDDDEFDGWAEDQLGDVEYDTELGKEMGKDAIRLARGEMDEAEFHEKYHEQVKDEFGVDDRPTKPEGFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT2</accession>
    <name>V6DXT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_93</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="9817" checksum="FCE078829BC11AD1" modified="2014-02-19" version="1">MPAGALPEDDELRQRVAAEAVRAVDRRTGALAGRVQPVDDGLAVLVRLDAAHRVVLAGLDRHRLREPVRALEVLREVEDVLQPVEDALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT3</accession>
    <name>V6DXT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase (TCE33)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C444_18227</name>
        <name evidence="1" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="5006" checksum="52CFAB3A74CBD984" modified="2014-02-19" version="1">MPPTDESRRAVFRYIAQHSYAGWPVYGMSPLYERTSLAGLESDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT4</accession>
    <name>V6DXT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_15414</name>
        <name evidence="4" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000041">
        <property type="protein sequence ID" value="CDK41142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078484.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000041.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116807at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="60"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="132" mass="14350" checksum="E9D1CE01D588690C" modified="2014-02-19" version="1">MATNDASERDGRHTVSIEIDPGADVAAVLGEIAELDVNGARVRDVSGEERSAVPVDPADLTAVQRQTLLRAVEAGYYSDPREATLSDLAAEFDISKSAVSQRLHGAEATIVRRVVEGMDREDRPTTRFDQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT5</accession>
    <name>V6DXT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000042">
        <property type="protein sequence ID" value="CDK41144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4768" checksum="9938F55A2DDAC36F" modified="2014-02-19" version="1">MSGGSLRWCETKERPELLSVPIVAREGTSIRRRSRMIGPLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT6</accession>
    <name>V6DXT6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HQ_2145A</name>
        <name evidence="3" type="ORF">BN903_100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="387" mass="43880" checksum="BD50393E75F4B0C9" modified="2014-02-19" version="1">MLSGMAGEGDAVAADRSANRDRAAIDDVEPDDDVEPDDDDIDAFDEDLWLDRISRKLGMGWLSDMLPGNIPPSYLYAVVTITTLELVVGAYSYAMGEPIIYLQNPFFVFQPIALFAAVYGSRSLRRRYYHVMKEMRIDDRVDESERLTDIIPSWLPWTVFLSALAINYIRMFALGGPITIYREMNLAAVIGWTVSNPVWASIATQFFAVYLSVELIAPRRLRNSDVGIDFLDPEGLGGLRPIGELIKHAYYYVVAGLIAFALLLYGPAIIGIEMERTAATNIVFTAIWAGSIATVGYAVFTLHRFMRDEKRHELRRLKSIEQRLVENRWDIKRYVVSGEDRDTVEELRRRMEMVSSTNEYPATFSIWSQLLLSIIIPKATQLLVARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT7</accession>
    <name>V6DXT7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rpl11p</name>
        <name evidence="4" type="synonym">rpl11</name>
        <name evidence="9" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077660.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="98187at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="7">
        <location>
            <begin position="68"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="158" mass="16425" checksum="83290326CAAC6C30" modified="2014-02-19" version="1">MAGTIEALVPGGQATPGPPLGPELGPTPVDVQDVVAQINDETAAFDGMEVPVTVEYDDDGSFTIEVGVPPTAELIKDEAGFETGSGEPQENFVADMSIEQVKTVAEQKSSDLLAYDTKAAAKEVGGTCASLGVTIEGEDARTFDDRVDAGDYDDVLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT8</accession>
    <name>V6DXT8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHOCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_16269</name>
        <name evidence="4" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078072.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="3">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="123" mass="13024" checksum="DC92BFF78E652EAA" modified="2014-02-19" version="1">MIVFDFVAVGPLMGGMAGSGMAGGMGGWMFAFPLVALFTVSVLIAVGLVGIKLLVSETDDGPDEGDPDETPVERLQRRYAAGELAEEEFERALERELEREGSDGVDERTAAETESAGEAARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXT9</accession>
    <name>V6DXT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_00057</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000042">
        <property type="protein sequence ID" value="CDK41147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="150" mass="16267" checksum="0C6C10F251AFFB7D" modified="2014-02-19" version="1">MSQGVVKQKGQTNSDRGMTVDDSLSEESKRQRDGIDNVGAFGMRTGESDLVFFQGILPEINGDVKGSEPVDEQIRMCLDRLELMLENRSASLDDVMKVEVQLADADAAAVVDRAYESRFDAVEFPPRTVVGVCSLPGGADVQLDVIAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU0</accession>
    <name>V6DXU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterio-opsin activator HTH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Hmuk_1556</name>
        <name evidence="4" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000042">
        <property type="protein sequence ID" value="CDK41149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="104"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="165" mass="17700" checksum="0E55E8420C10FA22" modified="2014-02-19" version="1">MTLSPDDCGCADDDCTEVVHAASAVGDRCPCEVFSEYGCVPQITEIDGDDVVVETYLPDRDVLTDLVDDLKAVVDGISLRRLKRIGSLEREEPRADVTLNLFELTEKQREAAAAAVAAGYYSRPREADLGELSADLGISKSALSQRLTAVESKLATSAFARATAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU2</accession>
    <name>V6DXU2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpl3p</name>
        <name evidence="6" type="synonym">rpl3</name>
        <name evidence="8" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000043">
        <property type="protein sequence ID" value="CDK41152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078490.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000043.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31722at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_A">
        <property type="entry name" value="Ribosomal_L3_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019928">
        <property type="entry name" value="Ribosomal_L3_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="PTHR11363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03626">
        <property type="entry name" value="L3_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK41152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="338" mass="37382" checksum="27F374BB42E7ABC3" modified="2014-02-19" version="1">MPQPSRPRKGSLGYGPRTRAESEVPRIRSWPEDDGAPALQGFAGYKAGMTHVMMVNDEANSPREGMEEAVPVTVVETPQMYAVAVRAYEETPYGQKPVAEVWSGEFHEELDRALDLPAEDTFETDAEELRALLDDDVVDDVRVITHTAPSDLSNVPKKKPDVMETRVGGGSLEERADFALDLVSEGGAHEFGDVFRAGQYTDVSGITKGKGTQGPVKRWGVQKRKGKHARQGWRRRIGNLGPWNPSRVRSTVPQQGQTGYHQRTELNKRLIDFGEGDDASVDGGFVNYGEVDGEYALIKGSLPGPDQRLLRFRPAIRPNDQPRLDPEVRYVSTESNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU3</accession>
    <name>V6DXU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6767" checksum="2E5CC9D432C6B8C7" modified="2014-02-19" version="1">MAVFDRSEIRDLLRLSECAISSRNRCCGRISDSLRSSRGTAHPNSISQHTALIRLDPLLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU4</accession>
    <name>V6DXU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000045">
        <property type="protein sequence ID" value="CDK41154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5352" checksum="E827E1DCA6AB1258" modified="2014-02-19" version="1">MIPVHTQRDIKGTIMVLNDDQRSNARVASGADLGKSMLAHDRRHPADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU5</accession>
    <name>V6DXU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5425" checksum="AA6EA0294D27ABC6" modified="2014-02-19" version="1">MPSCRSGRLWARCPDEDFNRAGGQALKRVLTEITETRPFYSLPNSPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU6</accession>
    <name>V6DXU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multi-sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="8">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C471_15047</name>
        <name evidence="8" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000046">
        <property type="protein sequence ID" value="CDK41157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334975.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000046.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="137"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="254"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="328"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK41157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="539" mass="60418" checksum="4D127F8298202F8E" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU7</accession>
    <name>V6DXU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5950" checksum="DC535D6B903C1748" modified="2014-02-19" version="1">MNVERERKQKPLTLMIVGGFFQVAVGVSGDISPVIGVGFGTVLIGLAWIWASKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU8</accession>
    <name>V6DXU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS240-type transposase (ISH102)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C473_06237</name>
        <name evidence="2" type="ORF">BN903_12</name>
        <name evidence="3" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="80"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="24279" checksum="8C21C07B905F47D4" modified="2014-02-19" version="1">MPENARLSGCLDEINLEFVEREATPELLMKLSIQLHLSGLSLSNTVSFLEVFGVDRVRSTVHNWVHKADLQPETGRSPNHVAVDETVIQLDNEQYWLYAAVDTDSNDLLHTRLEPTRTNVIADQFFAELCDKHDVEDAIFLVDGAVPLQRACDKHNLDFRYERHGDRNSVERVFREVKRRTTSFSNCFSNAKAETANEWLRSFAFAWNQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXU9</accession>
    <name>V6DXU9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S3Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosomal protein S1e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rps3ae</name>
        <name evidence="4" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000047">
        <property type="protein sequence ID" value="CDK41159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078499.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000047.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96138at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00359">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030838">
        <property type="entry name" value="30S_S3Ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_S3Ae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="24037" checksum="972223FDDF9DF89C" modified="2014-02-19" version="1">MSERSVSKSREQKRWYTVLAPEQFDRQELGETLAEEPQQVVGRTITTTLDQLTGDSNANNTKLTFKITDVGSDSAYTEFIKYELTRDYLRSLVRRGASKVEASITVLTTDDYRIRVQPVALTTKKADRSQEKAIRRVMIDKVHAAAEERTFEAFVDAIVDGNLSSAIYGDAKEIYPLRRVEVQKLTLEARPREVAAEEETAVDVDADEVAVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV0</accession>
    <name>V6DXV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="131" mass="13935" checksum="CBF9725377E1B535" modified="2014-02-19" version="1">MKLEHVDVVGVEPVERGLERLGEVLAVQLLRQFAVAGLRVVVEIVADLRRQRHLVAAAVDGPPDYLLAVAVAVHVAGVDVGDARVERVLDHPDRLFVGAVAPPIGADDPRAEADLGDLDAGVPQFAVLHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV1</accession>
    <name>V6DXV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4595" checksum="839479593FE0D864" modified="2014-02-19" version="1">MSFTGGMERRHKSDCEFAIVSPEDRTPKNALPSRSTSLKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV6</accession>
    <name>V6DXV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferases group 1 family protein</fullName>
            <ecNumber evidence="3">2.4.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CLDAP_10410</name>
        <name evidence="3" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.57" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="162"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="359" mass="38842" checksum="08AE9119BBA31087" modified="2014-02-19" version="1">MGHDVHILVPESWPNVPGDDEPSDSVPFSIHRHSSALHGYDGVYFLQGLSESIERIDPDGVITHGEPWQFITGQTGWICNRLGVSHAVFSWENLDRVPSSRVKRGLESLVYSRIDGIIAGSEATETRLRNRGFDGPITTAPQTGVDTEKFSPDVDGTDVRSSFGIGADSPLVLYAGRLVAEKGINVLVDAVPAVSKAVPEAEFLILGTGPMEDELRSQIDKTVDTDRVTLVTERQPYSRMPKIYNSADIFTYPSVTIDDWAEQFGYATVEAMSCGVPVVTTECGALPSVVGDGGLVCPEHDAGSLADRLSDLLTDPEYRREIGNAARERASTKFSLSGVAKTQVEFISQLSSSRSGGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV8</accession>
    <name>V6DXV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hisS</name>
        <name evidence="4" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HGTP_anticodon" evidence="3">
        <location>
            <begin position="9"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="10176" checksum="2FFC86E8DD878B09" modified="2014-02-19" version="1">MLSVGDTRSEAAALANDLRALDDDVVVEQDVSGRSFGAQLGYADSINAETVVVVGERDLENGEYTVKDMSSGDETTVPVGEFPPEEGLPTYEDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXV9</accession>
    <name>V6DXV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000049">
        <property type="protein sequence ID" value="CDK41167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4823" checksum="8E58486677A6CB44" modified="2014-02-19" version="1">MTVDAVEVTPVGERNPDSRHLPSEVVREWAGHTRQERLRALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW0</accession>
    <name>V6DXW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_04256</name>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000050">
        <property type="protein sequence ID" value="CDK41169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078506.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000050.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117149at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045490">
        <property type="entry name" value="DUF6432"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20024">
        <property type="entry name" value="DUF6432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="99" mass="10820" checksum="24912DED3A104443" modified="2014-02-19" version="1">MAAKPEYRDRPDVEVALLDALVDRGDEGMTVLELRAAVDADIDAVEEALSALKDDSLITVETEERVRVYAHDRVIPDPDAATDDASESLVDAIRDRIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW1</accession>
    <name>V6DXW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Malate dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_07199</name>
        <name evidence="8" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the LDH/MDH superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077691.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69007at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="7">
        <location>
            <begin position="147"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="304" mass="32535" checksum="7343EECA22023FDB" modified="2014-02-19" version="1">MTKVSVIGAAGTVGAAAGYNLALRDVVDELVFVDIPDQRETTIGQAADANHGVAYDSNTTVRQGDYADTAGSDVVVITAGIPRKEGQTRLDLAGDNAPIMEDIGSQLAEHNDDFVTVTTSNPVDLLNRHLYEAGDRDRHKVIGFGGRLDSARFRYVLSQRFDAPVKNVEGTILGEHGDAQAPVFSKVRVNGRDPAFDADEREGILADLQESAMDVISRKGATQWGPATGVAHTVEAVLNDTGEVLPCSVVLDGEFGYEDTALGVPAKLGSDGVEEVVEWDLDEYESDLLDEAAEKLSEQYEKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW2</accession>
    <name>V6DXW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="10447" checksum="24273E975BDF36CE" modified="2014-02-19" version="1">MMNVSEILGKYSTKKAIFILVIQRSGTDYQTSCLYEHRPKSVPLLLMWKYTQSVNSQSSAPATPEGPSPTCFADLVHDIVNIDIDQKLVDRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW5</accession>
    <name>V6DXW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_11665</name>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077689.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112029at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="182" mass="19864" checksum="313FD7644449C9D3" modified="2014-02-19" version="1">MFSLNVPLSPGVDRLATDLHPKLKGFDTVRERRTLVCKRFGVDDVRDPDDDAGATPTKDDVLDRLRGRLGRPLAEIDPFEVAVTGVDVFDVPASGSRPVVYLTVESEGLVRLHRRLCAAFGAVEGIEGDDYVPHVTLARGGNPEPGAVAGVVDAAFEPIRWRVHALDVWDPEFREVAATIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW6</accession>
    <name>V6DXW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thermosome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Hlac_2662</name>
        <name evidence="6" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="PTHR11353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="383" mass="41161" checksum="6D2FBBB6D7365380" modified="2014-02-19" version="1">MGNQPMIVLSEESQRTSGKDAQNMNITAGKAVAESVRTTLGPKGMDKMLVDSGGSVVVTNDGVTILKEMDIDHPAANMIVEVSETQEEEVGDGTTSAVVVAGELLDQAEELLDQDIHATTLAQGYRQASEKAKEILEDEAIEVSPDDRDTLVQIAETAMTGKGAENSKELLAELVVDAVLAVQDDDGIDTENVSVEKVVGSSIDESELVEGVIVDKERVDENMPFAVEDADVALFDGAIEVKETEIDAEVNVTDPDQLQQFLDQEEEQLREMVDHLVDIGADVVFVGDGIDDMAQHYLAQEGILAVRRAKSDDLKRLARATGGRVVSNLDDIEADDLGFAGSVAQKDIGGDERIFVEDVEEAKSVTLILRGGTEHVVDEVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW7</accession>
    <name>V6DXW7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4637" checksum="8DB28F6CE384DF46" modified="2014-02-19" version="1">MSVLLGECLTQPFGRVKFGENCGRQRRLRANFERSLARHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW8</accession>
    <name>V6DXW8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">C472_03758</name>
        <name evidence="12" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="CBVY010000018">
        <property type="protein sequence ID" value="CDK40726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078089.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000018.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47911at2157"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="324"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="160"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="261"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CDK40726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="434" mass="46146" checksum="AF7DF295B4D1AEBA" modified="2014-02-19" version="1">MRLSIIGSGYVGTTVAACFADLGHEVVNIDIDESIVETINDGDAPIHEAGLDELIAAHAGPEGTGRLRATTDYEAVHDTEVTFLCLPTPQNDDGSIDLSIMEAGATQLGETLAEKSGWHTVVVKSTVVPGSTEDTITPILEDASDTTAGEAFGVGMNPEFLREGTAVDDFLNPDKVVLGADDERALSDMRDVFDPLVDRADAPVVETDTRTAEMIKYANNGFLAAKISLINDIGNICKEFGIDSYEVADAIGLDDRIGEQFLRSGVGWGGSCFPKDVAAIIAAAEEQGYEPPVLNAAVDLNDRQPGRLVNLLAGHLDLAGARVTVLGLAFKPGTDDVRNSRAIPVVEQLQERGATVTAYDPVATENAKAYLDDVEYADSAAAALDDADGAVVVTDWDEFAALDEEFDAMANPVVVEGRRIVERRDGITYEGLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXW9</accession>
    <name>V6DXW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_13954</name>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="155" mass="17710" checksum="13D78FE02DA497BE" modified="2014-02-19" version="1">MALNIYVQLGRYPLKRHPIGPARKRSKRPDEAADDHRERHDGSPQPEPFEPVFERLRLVRVVVAGRRLGLAVSEPLARFRIGWRIGGSIPVGPRFAGRPFRVRLSVARSPAARALVARIFLALRWFGVDATRRRQRVVDHGRSRPGIRPYEAICR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY36</accession>
    <name>V6DY36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8837" checksum="43C3A0644FA09533" modified="2014-02-19" version="1">MKQPLDGICEENTVRYYDPRTASGAESMRMSSPVSKTIAVTRNPPANCRRSDGRDSASPDRANPTAATSELMLGTPRRIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY39</accession>
    <name>V6DY39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_84</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5455" checksum="A10ED4CA9D7A8896" modified="2014-02-19" version="1">MNPAATAERDPGRLGRRYRRRSRPESVRIGCWLLLYTPDYLMYLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY51</accession>
    <name>V6DY51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transporters inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_13677</name>
        <name evidence="6" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="148" mass="15924" checksum="722D15F50D6B3646" modified="2014-02-19" version="1">MPPLALIGFAIAWFGINDWGAAFIIAVGAFWINFYAAYGAVEGVSEDLLDVGRTLGVRGDLDAVRSIVLPAATPGIMTGIRTGLGRCWMLVVASEIFGVPGVGREIIRASNNLAVDQAIAYILVLSLMYLLVDVAFRAVERRVLVWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY53</accession>
    <name>V6DY53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2',3'-cyclic-nucleotide 2'-phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06664</name>
        <name evidence="2" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5_nucleotid_C" evidence="1">
        <location>
            <begin position="286"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="497" mass="52959" checksum="99BC0E4C558997F7" modified="2014-02-19" version="1">MTIIHDTHLQGRYGSLDEPANVANYVGLIDRLGEEYPDALRVGVGDDLASSVLSSVFDGEHIVDALNAADLDYDGFGNHDFDMGPDTFRAQVANSEFPWLCANCLDGRTGEVFAAEEGAMRYALTEVDGVTVGLTGILTEEAPNVASMGENAEVTDPAAALQEVVPRMREEGADAVVVLSHVASPVVESEVAPAVDGVDAYVGDHAARTYETPNVVNGSLVSVVGDEFEHLAELHLEVEAGEVTGHEFTRHATAEAVGRGLEPNDEVVGLVEEYRSRLDDAVGEEIGRTGTTLDCREPVVRREESNMGNFVADAMRDDTGADVAVQNGGSIRTDTRYEPGPITRRDVVNVLPFGNEVTVLEVSGGTLRAVLENGVSEVERLSGRFPQVSGLRYAYDPTNDRGERIVDASLGGEPIDPEATYTMATNNFIADGGDGYEMLTDAPRVLTPGNGPVLSSLIARQIEANSPIAPEVTGRVTVRNPPWEPLVEASSALVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY55</accession>
    <name>V6DY55_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_99</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10827" checksum="A26652E26AC013B7" modified="2014-02-19" version="1">MNGSVRSIWTSPPCDSRSRSARNAAYTVSSNNAARPNRRATTDSWRRHRFRRPVRAAAEYVTTNNTPAADRSQNLAVPNRKVSVSANDRDSPPGGRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY56</accession>
    <name>V6DY56_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="4">DERA</shortName>
            <ecNumber evidence="4">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="4">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">deoC</name>
        <name evidence="5" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078178.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="74992at2157"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="4">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="22201" checksum="28A583B7B462757E" modified="2014-02-19" version="1">MNREEFAASIDHTVLGPETTWADTRTVLDEAADHGMNACIPPCYVAEAAAYENAPDTIATVVGFPHGQHAPEVKRDEAVAAWEDGADEIDIVINVGRLKAGDDGAVADELSDVVAAVPVPVKVIIETALLDDGEKRRACEAAVAADAAMVKTSTGFADGGATVPDVELMSEYLPVKASGGVGSYEEAMAMLDAGAVRIGASSGVEIVEGHPESPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY58</accession>
    <name>V6DY58_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HalOD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06640</name>
        <name evidence="3" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077746.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109003at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040624">
        <property type="entry name" value="HalOD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18545">
        <property type="entry name" value="HalOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HalOD1" evidence="2">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="101" mass="10345" checksum="1EF8CE5379F9B8E6" modified="2014-02-19" version="1">MSSVTPEPNDPSSMSETARVRHGGSGPSPSLAVVEAIAALAGVEPADLSDEGVALYEHVDPDALNALVSDRSDADLDVSLTVAGYDVRVGPESAVAQRSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY60</accession>
    <name>V6DY60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6183" checksum="1EFAA700B0169BBE" modified="2014-02-19" version="1">MRNNKFSGILFDSVWMSRNESTDRFPSRQRVVDPFDDRAVNPVDHRASASEGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY62</accession>
    <name>V6DY62_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C462_11019</name>
        <name evidence="4" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077751.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109691at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="3">
        <location>
            <begin position="50"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="12685" checksum="06EBF266546C01D0" modified="2014-02-19" version="1">MIPSSPVAIGVVVAVALLALFVLVRRLRGPSAEARESKRAHEAAQERDAPVEIGETYEFGVTELTDHHSGSEVAVGKVQGFVVFTEDIPGGLEPGDVIRAKVLSFNEGRTSADATFVGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY63</accession>
    <name>V6DY63_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4246" checksum="AA62395D639E8443" modified="2014-02-19" version="1">MSKRRLDDIALGSAIPTLRSSMVMSEYRTHFLYVDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY64</accession>
    <name>V6DY64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10196</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="45"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="253" mass="28002" checksum="5FCADF0BDC60C5C6" modified="2014-02-19" version="1">MARRXXXXXXXGVLYGGVTYHRRRAETAHRDLETSNQQLQVLSRVFRHNVRNDLNVIRGYADLLGDRVDDDRSEGYVETIRETTDDVVAISEKLRVIEDASSEPPDGRVDLVDAVREAVGSVDVDDAEVTVETPSAAWIRADDSVAFPIREVFENAVTHNDASTRRVEATIRENGTTTCLEVTDNGPGIPQDERAVLQAEEETALSHASSIGLWLVKWMCETQGGTVRFEAGDDGTTVRLRFESTTPPATPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY67</accession>
    <name>V6DY67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4200" checksum="36DE3B743C021BD9" modified="2014-02-19" version="1">MIGHQLEETMSGTKSQLLIGNTTIRTATSTGDLPQHDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY71</accession>
    <name>V6DY71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_10246</name>
        <name evidence="3" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078200.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="94738at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024464">
        <property type="entry name" value="DUF2391"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09622">
        <property type="entry name" value="DUF2391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="237" mass="25396" checksum="B1667506033E441B" modified="2014-02-19" version="1">MVDSDERDADTGRADGSGERVDPARGPDEPDIDDLLAKLDALSDTVDEGHEREKVRQTISLVERMPGRAAFAERITKYTSRDLAESFVGAVLFALPLLVEGGVFEIAAWFAAITVAGVPVLLFAHVGFVFAAVAGLLYFADFRQIVIRHPILGIIPRRYAGVLLVSLTTSTVMLLFWGRLHEGDPTAVERLGRIAVVWAAAAFGAGLGDILPGESQGDDIGPLDLDPFDGDGPKRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY79</accession>
    <name>V6DY79_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C468_00195</name>
        <name evidence="6" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077767.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58376at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="49"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="302"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="420" mass="47687" checksum="F9CFA2FED2E2E382" modified="2014-02-19" version="1">MDSPFKGANDIFQTKEPFEEAYHPEEILERDEEIETFAAALQDVLDGFGPPNVFIYGQTGVGKTATTHKVTEYLEADAIEAGVNLTVFSINCNKRDTTYKVITHLANELYSEKTFKQGHHPDTLWDRIYTALDELRGSVLVVLDEIDKLGEDEELLYEFPRANAMGELEHAKVGIIGISNNFKFRESLSPRVKSTLTEREIQFSPYDADELRTILDYYADLVFYENVISDDVVPLCAAFTAQDTGDARMGLDLLETAGDIARHEDADQVVEEHVRIARSQVDRANTERIVTNRLTVQMQTVLVATTFLDVDQSADAKVKTIYSFYKDLCNRLDIDVLSESRVRDHLDTLDMFGLLETEEVNLGRRGGRSYIYSIVDEPRVVIETLYNMDRFENLFGDSAEEFLDTYEADTRSDIQTKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY82</accession>
    <name>V6DY82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_13920</name>
        <name evidence="3" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077794.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81806at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="25187" checksum="C33987B1B89E3261" modified="2014-02-19" version="1">MTQFTNEDRKRLRRELIEAGHDYFTRFGFDRTRVSDVTSEVGIGTSTFYQFFDSKEALYLTVLLSERERLFETLESAMVAAETPREEAEMILRTTLGEVRTNPLIRRLFVGGEIRRLESQLDGATYEGDLTSEQFESPTTFKRVLQQPDEWVEHDEVWIDDPDVVRGLMRSVLFVTQARNTPIIPDDSYEAIEEALIETIVAGLFTTEENTDRSTTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY83</accession>
    <name>V6DY83_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translation initiation factor 1A</fullName>
            <shortName evidence="3">aIF-1A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eif1A</name>
        <name evidence="3" type="synonym">eif1a</name>
        <name evidence="8" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3 6">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_008584833.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102432at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="PTHR21668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="7">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="11231" checksum="D6209FD2FCA4BF51" modified="2014-02-19" version="1">MSNGDGSGRNDLRMPDDDEVFAEVVEMLGANRVKVRCADGNERTARIPGRMQKRVWIREDDIVLVEPWDWQDEKADISWRYEKSEAEQLREEGHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY84</accession>
    <name>V6DY84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Natoc_0450</name>
        <name evidence="4" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="211" mass="24463" checksum="B2652D1CEDA28997" modified="2014-02-19" version="1">MNDEIFALETLTISDSEMAEHTDEAIMEATYQALCKHGYPATSISKITDEFSKSTSLLYYHYEDKENLLEDLLCHLLDQLEDQLVDLDQEGPYDYLMAVIDQLLPTQVDNNQFRFQRALLELRSQAPHIDAYHKQFQRLDELVLSEFTTTIETGIERGLFREIDPEQTAVFMYSTVYGALERGVSLEDASLLQQNRQTLEEYVRSNMLVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY85</accession>
    <name>V6DY85_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Glutamine synthetase</fullName>
            <ecNumber evidence="2 6">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glnA</name>
        <name evidence="8" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2 6"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078213.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47310at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="7">
        <location>
            <begin position="117"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="3">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="455" mass="50111" checksum="8E6BBFB6389A53E2" modified="2014-02-19" version="1">MTDEHAKPDGGLTAEEQAVLDEIEEENVDFLRLQFTDILGTVKNVSVPAHQAEKAFTEGIYFDGSSIEGFVRIQESDMRLVPDPDTFAVLPWRSGEDGSAAARLICDIVDTDGEPFVGGPRQVLKSVLEEAEEMGYSVSIGPEPEFFLFKTDDEGNATTNPHDNGGYFDLAPKDLASDVRKEIIFTLEEMGFEIEASHHEVAKGQHEINFKYDDALTTADNIATFRAVVRAVAAQHDLHATFMPKPIADINGSGMHSHISLFDEDGNAFADEGDEFNLSETAYQFMGGILNHAKAFTAVTNPTVNSYKRLVPGYEAPIYVAWSDTNRSALVRVPDAAGVSARFEVRSPDPSCNPYLAMASLIAAGLDGIKTGADPGDPVREDIYEFDDEKRQEYGIETLPPNLGAAVEELEEDEVLQEALGPHTSEKFAEAKSQEFSEYLTQVSQWEEDRYLETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY88</accession>
    <name>V6DY88_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C465_13850</name>
        <name evidence="5" type="synonym">cetZ</name>
        <name evidence="8" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CetZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="9"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="490" mass="51997" checksum="B8BB5104790A3567" modified="2014-02-19" version="1">MVVAGEHMKLALVGVGDAGTRIVDHFVRREQATGRSITAGNILVFNTDDRAFEDTREISEERQVLLGETHSAVKRRPNSTDVSVSAEDNGDADRVHTGTHTDIIDSYGVGGNPDVGATVAEAELPEIRRALDQIDETEVAATMLVVGLGGGTGSGVGSVLLEELNAIHETPVYVLGVLPSTTEPDHRALTAARGIRTLVPLADATFAVDNEAWRHSTDSVAARHNEINEGIVTRLLAVFGAGERDPEATSEMRVDSADLSRTLEIGGVTTIGYATHELNCDDNNLFARLLRLLSLSNDTDDNGADAATIKRLIRQALESKLTLPCAVDSADRVLLILSGPPNTISRKGFETGRYLLEEETTTVEVLAGDEPVSGATEITATVVLSNVTDIPRIDEIQRQAVATQPLSSLDDHDTAAGRDSDVDGDGREDEVDPDRVLTDDTAGGAGDGSVGEDDDAEVDDAAKSNAADSSVEAVDGETNHSFDFDVERDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY89</accession>
    <name>V6DY89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1877</name>
        <name evidence="2" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="206" mass="22330" checksum="87A930A28974A262" modified="2014-02-19" version="1">MTRPRSRRRLLAAAAPLALAGCLIEANPDATDGNGQAVEERTETESESEVGDPTTGSGAGNEGTAAQTDDTSAVANASDGENETPDPAGITVESTNISRIIESIYLSQIVADVAIRNSGEYTYGTLELRIDAYYEPPEDDRTYHPPRVDDRTAVGRTYAEETFDSFDTGTRTFENVVIRYDAEEANDSTDPAEFDLEIAVRRAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPA0</accession>
    <name>V6DPA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13628" checksum="BFFE690AEE6C8EC2" modified="2014-02-19" version="1">MTPEELAAIGVLKSSDRLLPELDEFSEALKSFAADYETLRYTGLSGEDALDAARFIYLPRVYLVESETFDESFVQELDAETVEVVVENGLTEFLASRGISTADDMVFDIAAVEDTAMEDGLDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPA2</accession>
    <name>V6DPA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075938.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="106" mass="11869" checksum="97F446EF2DBAD65B" modified="2014-02-19" version="1">MHNGVYTDIDEFTDAVDESGEIHRDFDLQGAPMNRTIGTLIEMNDEFDLLSVVTSHRHDLPYPTGADFHVTSVHEFADLIEKLGGNCIEDIEQNDDGSAQVGYHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPA5</accession>
    <name>V6DPA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK37991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK37991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7590" checksum="5C9CD677917CBDF6" modified="2014-02-19" version="1">MDSKEILPGTERIQFLLDTDSLDNLGNQEYTTLEKLVRYTDFGVPPHILTVKKHREASKKTWNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPA7</accession>
    <name>V6DPA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal sequence peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sec11</name>
        <name evidence="3" type="ORF">BN903_262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="233" mass="25097" checksum="B906BDB5869DAD65" modified="2014-02-19" version="1">MSQDDDGSGFVYPDPDSDSESEAIEYPEMEPPTDEGGGKSTIGLWIRDGSLGFGIVIVGLLLLTVAAGVWPPMTVVESGSMEPNINQGDLTIVSAPDRFVNENADENGVVTHDFAVQEGIENLGGYGTVIVFQDPQTNGPATIHRAMFHVEEGEDWFERANESFLHGATSCSDLRNCPAPNAGYITKGDNNPYYDQAIGLSRPIDGGWISSVARADVPYVGWIRLIFSGRLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPC4</accession>
    <name>V6DPC4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043902">
        <property type="entry name" value="DUF5786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19099">
        <property type="entry name" value="DUF5786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5786" evidence="2">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="54" mass="6265" checksum="4B8E6733C40EFFCC" modified="2014-02-19" version="1">MGYGEYDEDEYARFEGMRSFETDEEPLSGQHDGELRTEGGEDTTALIERLDEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG7</accession>
    <name>V6DTG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="202" mass="22546" checksum="D9F79E49B4BA4879" modified="2014-02-19" version="1">MEALSIVASTLLTLGLVILYQQQHRVLRYQQIPQLEISEFNMTDNFEFIQVDVSNVGGGPATSMDLRIDLYELSGEGPVQTAHGGLRRIESLGDGTEKKTRASSIRPSEINISFEAESKGVLGSGSRTQNQDSLASIVASELEKDRDVIYGKLSIEYINKFSENDAFEADFSLKFTQHNDLKYEVFDFQPWEDDHQHPALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG8</accession>
    <name>V6DTG8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0033 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03174</name>
        <name evidence="2" type="ORF">BN903_173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076307.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124510at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="1">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8605" checksum="49AB97787F009B75" modified="2014-02-19" version="1">MSAEYDIAETLDVKGASCPMPVVKTKGAIDDLAAGEVLEVLATDPGSMSDIDGWAAGTEGVELVDQEEGDDVYKHYVRKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTG9</accession>
    <name>V6DTG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="191" mass="21951" checksum="6C0481333796B27D" modified="2014-02-19" version="1">MSSVLDSQIFNGSRRLSLVEMDAKEKVEEVFESTTAEDLLESTEEEFVQEVMNEVEIEIPDIDFEDWEPRTSGEGGKRKLEIPLSYEGDAELLEIPPSNHDPQNLTARVTAGTLTFSFDLNDLDSDDPQGDIEESLNHLEEGLEALQEELQELKEEIQDDVRNEFRERKEQAKENEKKLEKLDFPSDDQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH1</accession>
    <name>V6DTH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9841" checksum="390E5C23A5267ABA" modified="2014-02-19" version="1">MYVCLWSLQKRKSQNRIGSLVTQFRYRLFELSQVCSTCFTYSVHSARSAEKYRAGSPSNSVTTYTGWLLHTDLCLGNEIPTEPETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH2</accession>
    <name>V6DTH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Resolvase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_3506</name>
        <name evidence="2" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="4"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="239" mass="27456" checksum="E01BA9767415AF15" modified="2014-02-19" version="1">MNRAVRIIRQSQGSEDSISLKQQRESTRKLADDLGIDPDTNLDTIDLGNCTGFSLFHKNESEDRLDDHPRIQELIENLRSGIWDYLIAHDDTRIARDHYFHVIEHAALEGACDLEFVVDVPQDRLTFSIQRAVESRVKRKEIERAKQAVEHRVEKGYWQGAPPFGLQFDDDGQFLIKDQKEWSTIEQVFVLHEQGESYRGIAKEIEDVSKSGVGKIVRDNRELYLTRLDADHPAVSSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH4</accession>
    <name>V6DTH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_07954</name>
        <name evidence="6" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077139.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51390at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="25"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="293" mass="31061" checksum="14B179133F8EF11E" modified="2014-02-19" version="1">MATSSEDPGPDGRIGSDVQAEIAETVEQLLRISQIVSKGSDEVTDLTNEQSASMREISEEVSDLSATVEEIAATADEVKSVSDDARALADEGCDVAEEAIDAMETVESATDGVSETVSGLEERVGQIDQIVDVIDDIADQTNMLALNASIEAARAGEAGDGFAVVAEEVKSLAEESQRNAEDIEELVDEIKSDTHETSDRIDAASEEIRTGIDRVDETVEMLHDIDDAVTEASHGVSEVAEATDQQAASTEEVSAMIDDAADTADEVATEAERIQAANDEQTKKIRDLDGLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH5</accession>
    <name>V6DTH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="65" mass="7774" checksum="31E6BC80E92F0B66" modified="2014-02-19" version="1">MGTIWSYRSGWTLTCYFIRVVWLSRSSLIRRMDPHRCSHWSRTWARCVTGRRVQLSRLIVTGDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH6</accession>
    <name>V6DTH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11649</name>
        <name evidence="2" type="ORF">BN903_124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="9875" checksum="71218EFF5DC96BA8" modified="2014-02-19" version="1">MVGAVVGAVVSAGLLAFWPPKPATDTSFALGALVLGFGVTAWSTAVGLGRTIEGLQARLDVSSNWTEASAREAFFVLSWTGTGWAFAAALLSVAFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH7</accession>
    <name>V6DTH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4616" checksum="3337831873C7FCEC" modified="2014-02-19" version="1">MTFVFGDSRDTHTYTKRATKRQNCENNWNNLENLFTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH8</accession>
    <name>V6DTH8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03134</name>
        <name evidence="2" type="ORF">BN903_183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076311.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="96961at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="15544" checksum="6A74375716A9187B" modified="2014-02-19" version="1">MPDSMAEQLRQDMACEGLLECFHGLKDLDRECYQVLVESGEPLTVDELAERVDRERSTAYRAVQRLLQTGFIEKEQINYDQGGYYHVYSPTDPSKITDEMQRMLNDWYAKMGQLIQEFETKYEQAETSAPATES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTH9</accession>
    <name>V6DTH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-sulfoglucosamine sulfohydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_01166</name>
        <name evidence="3" type="ORF">BN903_129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="39"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="374" mass="41189" checksum="8B0778AE37CB84CA" modified="2014-02-19" version="1">MERFRNTGQPDWDWWGRVWPTPGETLRDLGVEPGNRVAEIGSGNGYFALPAARIADPGPVYAVDVDGDLLAELDALADAQGIENLRTVEGDARDLPGLLPESVDVALLLNAFHGIPEPQAVVAGIAETVDDGGRFVVVNWRDRPREETVIGGEPRGPPTDRRLXXXXXXXLPRAKGTCYDPGIGTALLIHRPGVVEGGEVHDDLVTNVDFTPTMLDLLGIDPPTGVSGESFAPLLRGDSHDGRDRIFAEMTWHDRYNPIRAIRTERYKYVRNFSVLPEVFVPMDVTPTASGREVHEEFHVPQRPAEELYDLEADPHESENLASDKKPFETAAEASDPDPAHVDALDRLRDELEAWMESTDDPLLDGPVPYPDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI0</accession>
    <name>V6DTI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_05874</name>
        <name evidence="3" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="285" mass="31555" checksum="6C928284D4680414" modified="2014-02-19" version="1">MGQAILRGIGDDYEWRLLDREPLPAAKVPADVTDADLHVADITDERAVREAVADVGAVIHLAGDPRKTAPWDSVLRNNIDGAQVVMRAAAEAGVEKFVFASSNHAVGGYETDERTPNLYREDDDYRLDGTELPRPGNLYGVSKAAGESLGRFYHDEYGMSVVCVRIGNLTKNHPPREYERGQAMWLSHRDCAHLFDRCLRADYGYEVVYGISDNDRRYYSIERAREALGYDPADNSADYTFEGEPKPDPDSDTDRESVDDPDVTADDAPAEPNFPADPDAPSDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI1</accession>
    <name>V6DTI1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C449_12018</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077129.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115539at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="29"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="240" mass="28227" checksum="68DE9A77CFF556EB" modified="2014-02-19" version="1">MPETASRTVTLLNRDISYEVRHSDEATQPRIDVDIHGVRVVLPKDSTTDSEELLLENAAWVIKKKQKYDTYREQVPDREFEPGETFPYLGEEFEVIVERRPSSEIAENAFRLAEHHVEQTSIQRALETLYRRKAREYFEDRADQLADEMGVEYDRIEIRNQRTKWGSCSTTGTLGLNWRLMMAPPDVVEYILIHELAHLREQNHTDDFWSIVAEYDPEYEDNSEWLETNSANLIFSEQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI2</accession>
    <name>V6DTI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Insertion element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03893</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077125.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36015at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024442">
        <property type="entry name" value="Transposase_Zn_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12760">
        <property type="entry name" value="Zn_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="120"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="294" mass="34264" checksum="3719F6CE97823EFC" modified="2014-02-19" version="1">MIPLDVFGSESVAADLLQQVRWRDGVSCPRCRSDRTVRNGSYGHFQRYLCKDCDRTFNDKTGTIFAHSKIALRKWLFSIYAFLRFNTSLRQLQCEIEVTYKTIHRRVERFTEALDAPSLDLRGPVEIDEFYVSAGLKGRERDRWSRSRGLSRRGRGTYEQDKPPVFVLVDRGTERRYIVPAKSADESTIRLLLADRQQEPLTVYTDGFRAYDPLEEDESFDREYVVHGDGEYAADTVHVNTCESHASLARRWLSPHRGISKDRLTQYFRAFQLRRELYRKPGREALKHAVKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI4</accession>
    <name>V6DTI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10827" checksum="EB717398CB18B750" modified="2014-02-19" version="1">MSSPHAATRSKFGTMSAETNFRPSPRTTHCSTNSLAANRSSIGPGATFSRREHEQLLRALAEGDVPVRAELDXXXXXXXRNRYCTHSDGDVPHRDVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI5</accession>
    <name>V6DTI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4404" checksum="82E29FD7D9BB0834" modified="2014-02-19" version="1">MRPPRDWGFSGLDDRHCAKTSYVQPSDWGFSDRYVVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI6</accession>
    <name>V6DTI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">XRE family transcriptional regulator protein</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C468_03233</name>
        <name evidence="4" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334941.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="PTHR11630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM_N" evidence="2">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="MCM_OB" evidence="3">
        <location>
            <begin position="106"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="HSDR_N_2" evidence="1">
        <location>
            <begin position="289"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="418" mass="47745" checksum="4A61218840575BF4" modified="2014-02-19" version="1">MAQAGNQDLTERLIQFYRNNYREEISTLEQNYPNNQRSLYVDYEDLYQFDQDLAVDLRTKPEQMREYAEEALRLYDLPADVSLGRANVRIENLPDTIQTSDISAHNDQVGKLVAIEGIIRRATEEELKITEAAFECQRCGTMSYIPQSDSDYQEPHECQGCERKGPFRVNIDQSEFTDTQTVWLIENAVNLSSGTAPREIEIVIRDDLAGKAVTGDRVRIIGTLHLDQDASNSQSNPSFTPYLDGMSIEQVERDSSGKSGNQHTSIPDLETYTELATTALSTLPEDAREEETKAKLITPFVEALGWNKYDSMEVRLEYTDSKTTLRPDYALFGPESDIPDVIIEAKQIGTDLEQKEQQLYDYLRVFSAEWGVLTNGEEFYVYRRTSDNYLPEKLTEMKLKDLSQASIVDSLLRSSFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI7</accession>
    <name>V6DTI7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AlbA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CcarbDRAFT_2933</name>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="1">
        <location>
            <begin position="52"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="512" mass="58473" checksum="7E6AE27362BC3358" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI8</accession>
    <name>V6DTI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8664" checksum="ECE5CDBDA050FD44" modified="2014-02-19" version="1">MGPHRPDLGDGLVDHARTVDRAGKRGSGDGRVLGRGSPDGRDRSQSDLISVKSDLSQVRSGRPRAEDTPLPAPDTSSGPRPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTI9</accession>
    <name>V6DTI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="12379" checksum="1D804F3BD9C39713" modified="2014-02-19" version="1">MDALDTGVFQHRAGAPHGSELVDRRALRVVSEDVTEVRGHLVGSGRKVRHRRRLCGRSRLVVESNSEQHVVHVRCFVRSGYKLHRRSVARGIAASRSTLTAFYLVPPKADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ0</accession>
    <name>V6DTJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5787" checksum="41DCB8F233A7169D" modified="2014-02-19" version="1">MGAGGGEKLSRDTTDVYTRQRHKTYQAPLRTAHESGAFDTHTHARFPQKDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ1</accession>
    <name>V6DTJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="11078" checksum="F30CF4DD7D597399" modified="2014-02-19" version="1">MKPSYSRSTQSKKIWVCSNDECGHSANRDTSEYSDAENLFERHIRRIVESEDEEYSLQSLLDRLGEDEKVTGRRIWEKYAEIVDDDQISTNCFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTJ8</accession>
    <name>V6DTJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00915</name>
        <name evidence="2" type="ORF">BN903_203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076330.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99962at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="149" mass="15891" checksum="137209CD4CCD9173" modified="2014-02-19" version="1">MYDHILLPTDGSVGVDRAIDHAIDAAARYGATLHVLYVVDGGVVNAYSGDEFVDGAEGAEETLEETGREAIDAVAALADDAGVEAVTAMRYGAPHEEILRYIDEEDVDLTVMGSKTRSGDYRRMLGSVTERVSRQSTAPVSIVKTTVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK1</accession>
    <name>V6DTK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4321" checksum="D9906A7AF7F7EE2A" modified="2014-02-19" version="1">MVIRRETRRVASRGSAGLADRPASRIPDLPLPNDLFGSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK3</accession>
    <name>V6DTK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077133.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="8965" checksum="2A0A10309D365863" modified="2014-02-19" version="1">MNEVTSTSPSSTLGHSDDSAEIHESELNFNSDDEPLGTFLFLEPDELEEAGISPTQYETFQYCVTNGDIKLIPPEREVKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK4</accession>
    <name>V6DTK4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_00925</name>
        <name evidence="4" type="ORF">BN903_208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="57"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="197" mass="22177" checksum="BEE0A7476A350983" modified="2014-02-19" version="1">MELTDAERERYDEKQGTFVEYVREAGITFTSGSDYQELVKRSGNDPAAREALLAKQDAREIMMNAERKVAKLAGILDRHRDDRVIVFTGHTDLVYRLSERFLLPAITAETGAKERREILERFRDGTYGRVVAANVLDEGVDVPDANVAVVLSGSGSEREFTQRLGRVLRPKEDGGRATLYELVSAETAEERVASRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK5</accession>
    <name>V6DTK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_91</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4879" checksum="DAB7F413C229C981" modified="2014-02-19" version="1">MLLLAPPPTFTSSKQPLRGSSSDIYHFENVPPQSSIRIQTLPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK6</accession>
    <name>V6DTK6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Proteasome subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">20S proteasome alpha subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Proteasome core protein PsmA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 7" type="primary">psmA</name>
        <name evidence="7" type="ORF">BN903_159</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076615.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57654at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03756">
        <property type="entry name" value="proteasome_alpha_archeal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00289_A">
        <property type="entry name" value="Proteasome_A_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019982">
        <property type="entry name" value="Proteasome_asu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03633">
        <property type="entry name" value="arc_protsome_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PROTEASOME_ALPHA_1" evidence="6">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="264" mass="28622" checksum="268BC0786095C24B" modified="2014-02-19" version="1">MQGQSQQQAYDRGITIFSPDGRLYQVEYAREAVKRGTASVGIRAEDGVVLAADKRARSPLMEPESIEKLHKADDHVGVASAGHVADARQLIDFARRQAQVNQLRYGEPVGIETLTKNITDHIQQYTQVGGARPFGVALIVGGIENGEPRLFETDPSGTPYEWQALSIGSDRSDLRDYLEAEYEEGLSTDDAVGLALDTLAQSNDGELTPDGVGVATITVDDEEYTERPVDEIEAILDERDLLPADDDEADESGDGENGESAGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK7</accession>
    <name>V6DTK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mutS</name>
        <name evidence="1" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5395" checksum="BBBDECAD8C1FB499" modified="2014-02-19" version="1">METAAAAESDRLDPETRAVIEELGDVDVAETPPVELLSRVQEWQERLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK8</accession>
    <name>V6DTK8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_08094</name>
        <name evidence="5" type="ORF">BN903_96</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077159.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35427at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="4">
        <location>
            <begin position="30"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="3">
        <location>
            <begin position="106"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="362" mass="39026" checksum="2A1CE488ABE9AFC2" modified="2014-02-19" version="1">MAQATQEFGDWPLKRLMTEVCGSGHKSADDLTRAQATEAFERILAGEPDPTTLGAFWLANRWKRNTAEELGAYVDVMCERVEYAEPDADPVDCGANYDGKGRTAILGVAAGAVAAAAGTPVVVHSGDRVPTQKQDAYKHVLDELGVHTELTPSDSADMVDETGFGFYYQPAFNPAVDDLFDRRDQVGVRSFVNTIETLANPAGASTHLGSFYHLAFAKKVVDTFVESEFHDLDRVLMFQGMEGYDDVRPGYTKVAEWDAAGDEAGSEGASFTDFEIETAEYGMDLEEEDLAVDDVAADSAEITEAVLAGERDDAFADAVAVNAALRIYAGEDADSIEEGLELAREAIDDGSAAAVLDDLREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTK9</accession>
    <name>V6DTK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4253" checksum="349D0BDA45584FF9" modified="2014-02-19" version="1">MFSAIDGFETPPSPFKPYLRTTTGILKTVKLEWDDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH0</accession>
    <name>V6DUH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6474" checksum="2CC3E1FE41062CBA" modified="2014-02-19" version="1">MRIDHLSLLTHDVSHSYDDNFCQIVHVSGMYSVSYGVPRYFIQLDGDVVDCCLPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH1</accession>
    <name>V6DUH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monovalent cation/proton antiporter, MnhG/PhaG subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C464_08530</name>
        <name evidence="2" type="ORF">BN903_108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077397.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105926at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005133">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34703">
        <property type="entry name" value="PTHR34703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03334">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01300">
        <property type="entry name" value="CPA3_mnhG_phaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="11632" checksum="E9D47969553BBBBF" modified="2014-02-19" version="1">MTAAALETARVWLIVVFTLLGLFFSFVSMTGVLRLPDVYSRAHTASQADTLGAGFGLAAVALTVGLAGAGFKSVLLLFFIFLTNPTAAHAIARAAFEEGIVPWTNGDDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH2</accession>
    <name>V6DUH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent protease Lon</fullName>
            <ecNumber evidence="4">3.4.21.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C472_05322</name>
        <name evidence="4" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK39832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="186" mass="19476" checksum="5DCE90582545EC75" modified="2014-02-19" version="1">MTPTQGGGQVIATGQLKEMAEESVQNVSAIIKKFSDENISEKDIHIQFIQTGQQGVDGDSASITVATAVISALENVGVDQSLAMTGSLSVRGDVLPVGGVTHKIEAAAKAGCTRVIIPAANEQDVMIEDEYEEMIEIIPVSHISEVLDIALEGETEKDSLVSRLKSITGSTLKDGNVSSPSSPSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH3</accession>
    <name>V6DUH3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L31e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpl31e</name>
        <name evidence="6" type="ORF">BN903_162</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ribosomal protein L31e family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076617.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115384at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00410">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_L31e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_L31e_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="SSF54575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10417" checksum="AAA7160AD46A3271" modified="2014-02-19" version="1">MSTNDFEERVVTVPLRDAKDKPVQQRADYAMKITRQHLAKHFSVEEDDVIIDGSVNEAVWSNGRQNPPSTVRVRAARFVEDGEPVVEAEHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH4</accession>
    <name>V6DUH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C445_06705</name>
        <name evidence="2" type="ORF">BN903_143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="103" mass="10975" checksum="6CDC67A2F4E173DE" modified="2014-02-19" version="1">MTWLETTTLTVFGLPALTWALLTTGAIAIRGATSTDLHVQTPSSLHISLLFGVMLGGVAAVYLATAGGYSTLWSIAAYVTVTGITIFWYWLMESDTVDTPTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP0</accession>
    <name>V6DXP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_05011</name>
        <name evidence="2" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077629.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114990at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9586" checksum="3B83C1D207910261" modified="2014-02-19" version="1">MNPYIDLTIIAAKTAILVLGGSITYYALRAYDRTGDRSLRELGIGFGIVTVGALLGGVSHQIIGADLAVGIAIDGLLTAVGFAVIVYSLYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP1</accession>
    <name>V6DXP1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_15864</name>
        <name evidence="7" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000033">
        <property type="protein sequence ID" value="CDK41102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078451.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000033.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84339at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="33"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK41102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="253" mass="25826" checksum="0297E5BB378F1D31" modified="2014-02-19" version="1">MPSPLALLSRPIGSVLDRVRDAFDTPRAGAIAVAILVVVTIGTTLGIVALGGIFDATVDQQVTVDNPDRPPESTCERFGDDPDSVFGERCDEPARIDVDAGEELRDAANGYLHYGLIGVSVWWGIFSLALHVGALFAGGSGSVGDTFVIAGWALVGELLRVIAGVAAIWVALSNAAITGSTFEAIAEEIVAAITGTTGPLLVASAVAIAVQWVIVVGGLEAHHDLDRGAAAGVATVFAAVALLLAVPANFGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP2</accession>
    <name>V6DXP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5862" checksum="FE9AA35BC0CAC506" modified="2014-02-19" version="1">MIPLSDTSSRSNCAFDAPSDEHVRKRLCGLVDDLADDGLVESDATGGDVVVSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP3</accession>
    <name>V6DXP3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AbiEi_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Huta_2938</name>
        <name evidence="3" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077633.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72343at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025159">
        <property type="entry name" value="AbiEi_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018547">
        <property type="entry name" value="AbiEi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09407">
        <property type="entry name" value="AbiEi_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13338">
        <property type="entry name" value="AbiEi_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AbiEi_1" evidence="2">
        <location>
            <begin position="88"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="277" mass="31042" checksum="B08123BB1152DA22" modified="2014-02-19" version="1">MEPTNEEENQRKSLSTRESRALSRLASEDRQIITINDLVDVLDIPRKSAKDMAYTLKEKGWLERIAHGKYLILPLAAGENAVYTEHEFVIASALVEPMYIGYWSAMNHHGLTEQMSRTVYIVTTERAQDREIHGVTYRPVSVTDQKFFGYQPTAVGSNQVNISSIEKTLVDCADHPEFCGGIGELAKAIQNAVEQGCSWERVVEYLRRVGNGAATKRTVYLADQLDIDLPEYDELVGEFTTGYPLLDPTREATGTRDSTYQLRLNVGPESFLPGGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP5</accession>
    <name>V6DXP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_08979</name>
        <name evidence="3" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077638.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104239at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="108"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18516" checksum="0B91CB35359F88C9" modified="2014-02-19" version="1">MSLTARDLMEPDVKTVSPDDDVAEVFKRFARYEFSGFPVVDDDERVVGVITESDLVDLFEPEDETLWIPIGLPPFVDTLSYQVKRPWADLDLGVDLIRNADRPISEVMSADVATVTPDASVDAVLDLLVGDDPDINRVPVVDSDGWLVGIIARQDVIRAFRDKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP6</accession>
    <name>V6DXP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_08989</name>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077640.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124405at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="90" mass="8874" checksum="2EEB777E29C0CC6C" modified="2014-02-19" version="1">MERLYVFNGAFAVIGLSIGVPAIRSLAAGDHGIGVLLMAVGGVGLVATAGYESLRTDPEGFTASGGALLLLIGAACLTLLGTVLSEISGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP7</accession>
    <name>V6DXP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000033">
        <property type="protein sequence ID" value="CDK41099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6166" checksum="5287A48AF883AF33" modified="2014-02-19" version="1">MYTKITEVFMYRPGIVADTRTPLALVESHAEMNGSSCRRPDAPQRAVAIAGAVMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXP9</accession>
    <name>V6DXP9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
            <ecNumber evidence="2">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08856</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078455.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000034.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103066at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="14"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="213" mass="23119" checksum="9C520D12056CB598" modified="2014-02-19" version="1">MEPIAVTADAEEFTCNAYLVVGDATTLVDAGTMPGVEDAVAEALAEADADGLDRVVLTHQHHDHVGELDAVVDRFDPEVLAYADHPHRDVALEAGDEVFVGDEACEVVYTPGHADDHVSLVGDERLYSGDVVVYNDGAFSDGSFGRTDMAGQSRERLIESLHDLLDRLPDTVEAMYPGHGGVYRAAEGPDSVREVIERATERAERREPKYPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ0</accession>
    <name>V6DXQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4566" checksum="1494A4FB767F4A77" modified="2014-02-19" version="1">MLLTVAFGDRSEARATAPQIGRFSPCVERSRLQNYQLLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ1</accession>
    <name>V6DXQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3890" checksum="DD7E77C0F844A3F3" modified="2014-02-19" version="1">MARARERSPPATANGTARGSRWRSSEAKTASDEAGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ2</accession>
    <name>V6DXQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="330" mass="36120" checksum="A6B49B6EFADD17F8" modified="2014-02-19" version="1">MEGVVESGDRDLRLEGVLLSPERVAVDRDVDQPQRLDPVVLRVGRADDEPGAGGEDGLAGRDVVSDLGGDPLAVDQPRDGRRLPARHEEDVAVGHDPRVPDLDDLRGLVVGGRGVADGGGVFGHVALNGDDACFHTDRWGGRVEKGRATRPDRRAEKRERRGSLRDRQREDLDEHAEENAERDHRLGVDRDGVPVLVVEVADQSRAGHQPAGVGTTHVRLCASPRSKRFVRRRDAAVFSRLFRRRRFPVVSAESSSPRNRRLRGIAVSAGSSPPVGRRVRGVIASVVPPSSRGFVSRAHEWETLMRGPAVVEADYDRSTAGFPRRVVRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ3</accession>
    <name>V6DXQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C471_09535</name>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="216" mass="24831" checksum="B9E5F3D7635D5D64" modified="2014-02-19" version="1">MDPTASKIVLAIQRGDSINRIASKIDISYSWVYDWIERLENADIIVNTDNGLQIVDHEMRQQYAEMTAALYSRDPISQEDAYVIPHFAGMEFAYTEIDAAYVWTQGGYQIARSHDDYPVFIEVHDRDVDRWIGFFQQFGIDMTINERPDASDVNGNVHYVLFPKTNDIDTEWVDGNPVIPLDTAVDQMIENRPAYEPALEIIADEYDRDIDARTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ4</accession>
    <name>V6DXQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_01299</name>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="6712" checksum="16E1166BF2E5648A" modified="2014-02-19" version="1">MRPEAIGDAVDALDGASVAFESLSWSEPSLEDVYLRLTGEEYAHRGDERAVTKTVGDAEGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ5</accession>
    <name>V6DXQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="6573" checksum="2DB4E5E9BEEEDFD3" modified="2014-02-19" version="1">MEGGQRAPGRGASELIRGDDWEPVPDRSPNPGDPSRDRVTGPPVERFSFGREIERNGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ6</accession>
    <name>V6DXQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078047.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25194at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="356" mass="40970" checksum="2B1786754F47D49C" modified="2014-02-19" version="1">MDIEYKRDNDGYDIRYVEGARHGRVPHSEICDDETEYVIRYVTSEEGTSRWEYRHLGSGYRNVDKVIPTLTKLPTLDDGQNVQILLNFGRVEEEFGMEKVGSLYGSDEYLPVYRLSPGMERTLNITYQDEMTLPILDSEPSARGLGGSPTDIAPRLFAAILNLLAKSDEIEEWHEYWNDDSDPFQQGEFYETVYAPLFVAYSIVDEEIVELVNRYHLEQRNDKEIKKSYMHCGFSNKIDNITPLLTPEEEEVIREAWKYRNDLIHGIHSRFGVQIMDIDFEVLSKNLLFSIMKARTLNSYVNSAEYRIGVTTPEEAVSHLKGDSNLQDAVTAAQKAIRGEMHAKSQLFGIDEKQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ7</accession>
    <name>V6DXQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C470_07454</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="24"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="231" mass="26072" checksum="FB7B072D166607F4" modified="2014-02-19" version="1">MAPELDEIDLGTVPLGRTGLRTSELQFGTWRFGRVTEAGNVEIDEDRAHELLDAYETAGGRYIDTADVYGGGDCERWIGDWLAERDRERYTVASKVYWQIRDGDPNSRGTNRKNVRHRVDALLDRLDTDYIDVLYIHRWDDETPARELMKTLNGLVESGXSTLPRRVDAPPERLEGRPRQRDRAQRGVGAVQSAPAAVQPRRPRGRRGITSSSRASGTSPSPRGVRSDRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ8</accession>
    <name>V6DXQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_09039</name>
        <name evidence="3" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077644.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122436at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="173" mass="17966" checksum="AB3C661A70DE1B4E" modified="2014-02-19" version="1">MSPPGGSPDNERLDSDSPDSGRLRRHLVGNRRPRRALLLSVAVLLAAVSVAFLAGASVGLYVFFGWLVIVPAIAVAGGLVGAGLTPTTGSLGLIAVWGYVFPPLLGYLTGEWAVGSRYSYPRMLGYAHGSARAELMGGLESVVEFALPLAVVLGTVGYGVGTTVRWGARRVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXQ9</accession>
    <name>V6DXQ9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">trpS</name>
        <name evidence="10" type="ORF">BN903_75</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="400" mass="44597" checksum="B5BA2A5FF58C5E11" modified="2014-02-19" version="1">MSWSEIDEHARNYLLSLLALGFDAEGGEIYRQSDNRTVQDLGFELGSKANFSEFEAIYGFDGETNISHMQSVITQTADILYPQLVDEPKPTVIPVGPDQDPHVRLTRDLATRVRYFKVTEAFASFELDDDERRLVRAAYDALAADADSSETDVRCEDAADWLADYEPPESDRESVDLAAAKASALDKLEAGGKEPLRPRVRFFDRNATDEAFEALIEAVEGEKRVFEGHVDAFDLTRGEAESVAREVEIDHDGFGFRQPSSIYHRFMTGLTGGKMSSSIPASHISLLDDPEDGYDKVRSATTGGRDTAEEQRELGGEADECPVYELYAYLLAGDDDELTKTVYSECVNGERLCGGCKEQAAELMREFLEDHQEKREEAEELLDDLDIDLDSNRRGTGGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR0</accession>
    <name>V6DXR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000035">
        <property type="protein sequence ID" value="CDK41114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5207" checksum="E77E2D63000975D2" modified="2014-02-19" version="1">MKLSTADGFHIVFAQCGEVTDESPVRWRVPPSGRLWRPRGAPREGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR1</accession>
    <name>V6DXR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exodeoxyribonuclease VII, large subunit</fullName>
            <ecNumber evidence="8">3.1.11.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">xseA</name>
        <name evidence="8" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078051.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="24568at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_anti_2" evidence="7">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="6">
        <location>
            <begin position="138"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="456" mass="50296" checksum="3A3DF379C40C191C" modified="2014-02-19" version="1">MAADDDTGSGHVEIDEPVWSVSRLNNEIAVTLESAAERFPTYVVGEVSDATAKGYGTFFTLRDVDSEETIQCIVWSSYRDRIDESITESEEVIVRANVDFYADGGRTQLNVKNYWPVGDSDRSQELEALRAELNEEGLFDSDRKQPLPPFPSNIGVITSLTGSAREDFRESTWGRAPGVTLTFFGATVQGTNAATSIVGAVQQADRDPDIDTIVVTRGGGADDTLWCFNEEPVVRAIADCATPTVVAVGHEDDETLAEDVADQAAMTPTDAGIVATPDMSTIRERVDTIERRLQTGYETVVSEQLDALSRRIENAVIGLEREVETRQARLQRAADLEQRIDTAYTTLTGSRLSEIDDRIETALQDIEHTAETEAVTVRAARGRIGGLETRIDRAYETYVDQETETLERRIEEAYRDIETDTDVREAKQEAQQLRIIILVLVGLLLLGVALWAVGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR2</accession>
    <name>V6DXR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetamidase/Formamidase</fullName>
            <ecNumber evidence="1">3.5.1.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_09069</name>
        <name evidence="1" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.49" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077681.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104958at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004328">
        <property type="term" value="F:formamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="PTHR31891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="312" mass="32371" checksum="7C1CE8F0A10E0AB2" modified="2014-02-19" version="1">MSREVVSHRDGHVYEFAPEMDPVYEAADGESLTVETVDSLNGAIQTDDDLLDAIPEEVNAATGPIAVAGASPGDLLAVDIEAVRVAEDRGRVLTAPGFGLLRDDPEIDHPATRITEVDRDGAAAAGSDDGGRIEFEGIDVPIEPVIGTIGVATGGETVSTLTPDDHGGNLDTTDVTGGTTVYFPVFQEGAMLAMGDAKAAMADGEMCGTGAEIAVEVDATLSVIEDPPVSLDRPVVDTGDAVKTLASAETVEEAVELANGDMLDLLAHHHGFSRTDAYLFSSLVGGLEISQVVDPQVTARNAVPSEYLSLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR3</accession>
    <name>V6DXR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000035">
        <property type="protein sequence ID" value="CDK41117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7958" checksum="EAEC75600E1C6CFA" modified="2014-02-19" version="1">MRPQLESLLLGKSLKRSLRYLGYSVILMGLFFGQLYLTGNFDVGTSSSLLMSPLGATVSASILAGIHIEMTEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR4</accession>
    <name>V6DXR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PAS/PAC sensor signal transduction histidine kinase</fullName>
            <ecNumber evidence="1">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_02794</name>
        <name evidence="1" type="ORF">BN903_80</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6152" checksum="B43410274DFEA02B" modified="2014-02-19" version="1">MFTEARETALEHASGLGLWLVHWIVTESGGDLKIDTREPTGTVVRMWLPRAAEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXR5</accession>
    <name>V6DXR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tubulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02619</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000036">
        <property type="protein sequence ID" value="CDK41119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="96"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="476" mass="52495" checksum="47612496550C34D1" modified="2014-02-19" version="1">MRRDEFAERDYKFVADLEPMSVVYGEGDDMKRRMTDRVPKPGAVAEEAADDAEIKTGLKIPDDGVFLGHLSVGGEKVRTAAEPPTVDYRVKDDYADGDPLAFRHTLVAGGTGSGKTHASKNVLRQYLDADRTYPMGDGRESRMAVVQFDPQDEYAQMHDDNPDLDDAFARRLEREGIAHGGHDDTVALVPRAANATYPGEGHRAERVEFTIPFSLARDMPWLVAGSGLNDNQYPALLTLLNRFFDNYGDSGTYSQFLSYLDDPALKEELHESGRVHEATFDAVKRRVRGVPSGVFDQDAKPITELDHTLVRPGGLSVVPTYHLPTSRQKEIVVLAVAGLLIDDKLSNDPASDRIKETPLLVGMDEAHNFLADADNVQAQKVVQKFTEAAKQGRKERLGLFLITQDPQDVAESVFKQVNTKVVLNLGDEDAISSVNIPSNLAGKVPYMEKGQMVVYSPDNSEPVELIGLSECVTRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS0</accession>
    <name>V6DXS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_01956</name>
        <name evidence="1" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="12861" checksum="74C0AA1D69D2C7EF" modified="2014-02-19" version="1">MIMSKGHFYSAGESVDYGTAACLFPVDELDANVFQHRDAQLTLEAVDGDAVIIVSPTSLATGYKLGGHPVTAIRVDSLPVNITATLDAAVEDDIETFDLIQIGRWNHSSPNHSLAEFTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS1</accession>
    <name>V6DXS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02724</name>
        <name evidence="2" type="ORF">BN903_85</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077654.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000011.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130309at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="6926" checksum="B98AE91A4803BA2D" modified="2014-02-19" version="1">MAVELHAAIPGALDRADLLLLAFPLLFVAVYGALALNTGDGIPPLAGASAVCCLLIVDGVFLNPPVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS2</accession>
    <name>V6DXS2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemL</name>
        <name evidence="9" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000038">
        <property type="protein sequence ID" value="CDK41129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078471.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000038.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264at2157"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK41129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="445" mass="48264" checksum="AC697EF30198902A" modified="2014-02-19" version="1">MNHERSRGLYDRALSVMPGGVNSSVRANMPHPFFIERGDGGHVIDADGNRYVDWVMGYGPLLYGHDLPDPVEAAVQSHVAEGPMYGAPTEIEVEHAEFVARHVPSVESIRFVNSGTEATVSAVRLARGHTDRDKIVVMQGGYHGAQESTLVEGSADDPHPSTKGIPEEFAEHTLPIPFNDPQAAKEVFAEHGDDIAAVLVEPILANTGIVAPIDGYHETLRDLCDDYSSLLVFDEVITGFRVGGLGCAQSKFGVTPDVTTFGKIIGGGFPVGAIGGKAEIIERFTPAGDVFQSGTFSGHPVTMAAGKATLEYAAENDVYEHVNRLGRKLREGIAEICAERAPEYTVVGTDSMFKTVFTRDAPDDVDACCAGGCRQNPDCARYETCPKTGADVAAAATDRWERVFWQEMKDRGVFLTANQFECQFTSYAHTEEDVERTLEAYREAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS4</accession>
    <name>V6DXS4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TATA-box-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Box A-binding protein</fullName>
            <shortName evidence="5">BAP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">TATA sequence-binding protein</fullName>
            <shortName evidence="5">TBP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">TATA-box factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">tbp</name>
        <name evidence="6" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000038">
        <property type="protein sequence ID" value="CDK41132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078475.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000038.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83880at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04518">
        <property type="entry name" value="TBP_archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033711">
        <property type="entry name" value="TBP_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="PTHR10126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="1" evidence="5">
        <location>
            <begin position="11"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK41132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="186" mass="19605" checksum="F6BFD591057B12BE" modified="2014-02-19" version="1">MTADPKETITVENVVASTGIGQELDLQSVAMDLEGADYDPEQFPGLVYRTTDPKSAALIFRSGKIVCTGANSIEAVHGSLDIVFDALRALNIPIEDPEITVQNIVTSADLGKSLNLNAIAIGLGLEHIEYEPEQFPGLVYRLDEPEVVALLFGSGKVVVTGGTSPADAEAAVDVIVEELNGLGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS5</accession>
    <name>V6DXS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3481" checksum="29D3BC1DFFF63D4D" modified="2014-02-19" version="1">MSTDADAAGEAASGASPPASVGLAGFKCGLGDPEVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS6</accession>
    <name>V6DXS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase E1 component</fullName>
            <ecNumber evidence="3">1.2.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_02203</name>
        <name evidence="3" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000039">
        <property type="protein sequence ID" value="CDK41134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="2">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="201" mass="22173" checksum="A100530B9A47DAF2" modified="2014-02-19" version="1">MNFAGVFDTPTLFCCHNNGWAISIPESRQTASDTFAAKATAYGFDGVRVDGMDPLASYAVTRKAAERARSNGGDGEEGDAPRPTLIEFVEYRFGAHTTADDPSAYRDPDDVDPWRALDPIDRMEAFLRETGRIDDEGVAAVRAEADDVVADAIDFAESIAAEPSDMFEYAYAELPPEIRRQRDELLAAVERHGEEAFLREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS7</accession>
    <name>V6DXS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uracil-DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_02684</name>
        <name evidence="1" type="ORF">BN903_90</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000011">
        <property type="protein sequence ID" value="CDK40180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9945" checksum="AC209C64AFA757E3" modified="2014-02-19" version="1">MINPQIIVPVGERPLRELAVEYTTRRPDSFDVDAEHATTIRGRGFELVPMKEPATMTDAEADAFRDHMRESVLSRDYRQTKGRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS8</accession>
    <name>V6DXS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6481" checksum="6831F9B5424F394D" modified="2014-02-19" version="1">MSDTDVSLAARAFGPSAGEHAGEIIAGRPDSLSGRGNSRRPPAALGARWAGDAYVAVGYQPVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>V6DXS9</accession>
    <name>V6DXS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_09216</name>
        <name evidence="1" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000040">
        <property type="protein sequence ID" value="CDK41137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045396">
        <property type="entry name" value="DUF6517"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20127">
        <property type="entry name" value="DUF6517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="162" mass="17718" checksum="A5411B901ADC932E" modified="2014-02-19" version="1">MSEETLSREVEAAGQTREVRVTNTVAEYDKAVELFGERYQAAVFAAVTTPRIEVLGQALNPVAEFSTRERAEIILNRFENVGDLERGSEYTTTVLESDADVVVYTAQGEIEGTGASTELELHIGEPVSVDDDFVLPLAAYPAAFSDGENVRLMMNGIEHESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY10</accession>
    <name>V6DY10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="153" mass="16979" checksum="231B12460C41B9D0" modified="2014-02-19" version="1">MAAPHPTVHVTPQSTPRIGPPRRRRRRVRGRRLLRADRSPRTGGRRRVGRHRHYPVRLRRRAGLFAVAAVLXXXXXXXXXXXXXXXXXXXXXRLPGRRLLPSEVDVVRVSRLVGLSLTPGSEFVLLAELLGGALATGLAWSLTPPVGHCSDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY13</accession>
    <name>V6DY13_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L21e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">rpl21e</name>
        <name evidence="5" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006112901.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="GeneID" id="55595157"/>
    <dbReference type="OrthoDB" id="107212at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00369">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_L21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_L21e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022856">
        <property type="entry name" value="Ribosomal_L21e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10575" checksum="1352EF58ACA12C41" modified="2014-02-19" version="1">MPSSNGPQKATRDKLSNKPRNRGTSPPQRAIQEFDEGSQVHLKIDPSVPKGRFHPRFDGRTGTVVGKQGSAFKVEIPDGGKTKTLIVTAAHMRAQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY15</accession>
    <name>V6DY15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C465_15781</name>
        <name evidence="5" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077727.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49614at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018080">
        <property type="entry name" value="Band_7/stomatin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01270">
        <property type="entry name" value="BAND_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="63"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="409" mass="44972" checksum="8BD613FA972BD69F" modified="2014-02-19" version="1">MGTQGPRGGSAELADVMDEVPDGVWQYLALGVALVVGFALLSQSLVYGVAALAVLLAAVTVVSAVEIVDAYDKEALTVFGEYRKLLEPGVHLIPPFVSRTYPFDMRTQTIDVPSQSAITRDNSPVTADAVVYIKVMDAKKAFLEVDDYKNAVSNLAQTTLRAVIGDMELDDTLSQRELINNRINEELDEPTDEWGIRVEAVEVREVSPSQEVQRAMEQQTGAERRRRAMILEAQGERRSAVEQAEGDKQSNIIRAQGEKQSQILEAQGDAISTVLRARSAESMGERAIIERGMETLEEIGKGESTTFVLPQELTSLVGRYGKALSGSDVQDMEGLDSKEFDKETEKLLGLEDIESALEQLDTVADSDLRTDETRDADTARDVDLAKQEKETREADRDIELESESERPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY16</accession>
    <name>V6DY16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonucleotide reductase</fullName>
            <ecNumber evidence="2">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C465_15771</name>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077725.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="36566at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="39946" checksum="1BBF7B74E0508618" modified="2014-02-19" version="1">MSESENTDTNASTGTDIETDIFSERKQLKPYEYSEFLDYVEAIRNSYWVHTEFNFDGDVQDFKVNTTPAEQTVIKRTMLAIAQIEVQVKTFWSDIYEEMPKAEVGNVGMTFAESEVRHMDAYSHLLDVLGITDDFEQVTAEPAIEERIEYLDEYLEKSESDDEREYVMSILLFSTFVEHVSLFSQFLIMTSFDKHEKKFKGIANAVEATSKEEQIHGLFGIELVETIREENPDLFDDDFEDDVQEACQQAYEAETEILDWIFDDGELEFLPRAHVDAFLRDRFNQSLENVGVEPIFETDDDLLEETRWFDEDIMMTKDNDFFSKRSTTYNKHTQSVTAEDMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY19</accession>
    <name>V6DY19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalamin-independent synthase MetE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_13502</name>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meth_synt_1" evidence="1">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="147" mass="15774" checksum="45F1CEB927210F28" modified="2014-02-19" version="1">MTTPPAEGEESTATDAIATVADATDADVVVQTAYGALGEKLYAHLVDEAGADALGLDLVAGDRDDTVYNVQEFGATDSLALGLVDGQNTLVEEPETIAERVEWFESQIPNEAFDRTYLTPNTELFYLPTNKYRAKLNTLAAATEVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY20</accession>
    <name>V6DY20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="8052" checksum="0713891581DC7CA6" modified="2014-02-19" version="1">MYSNKGRHRGYQVADVLVFAYISNEQTHRNSGTIWMANGQTPPPPFPQLRDSTGRLLKLRLTGCWCSGHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY22</accession>
    <name>V6DY22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hqrw_2444</name>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077729.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76971at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="243" mass="27220" checksum="76185DC3D5273A22" modified="2014-02-19" version="1">MRENNLTSVTEMILGVLTESRGFVFHLTLNFALILAVIVLEWGLIEIVVTYLIEIAIIHFIFLIVGLFTPQPIDDRDGDVWDTKPTTLQPISLLPPVYRRNIRYIGYKSIFPGVLIVALMIGIFSNSDVVSALPRSVGVAIIGITLFQLGQVWRYFIVDQSYQDKSPQDAVQFAFAPVGEVLFVMFYAFIPVTFVIVGGVIVAVIDLPSRLVLLLVYLVPIGAVRAWMRSLDPQTDDLEMRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY24</accession>
    <name>V6DY24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="7785" checksum="E3F7BFE9D2CFEACA" modified="2014-02-19" version="1">MRVLRNKIAGFPLPVDPRLVRIGVRRPGSAHLEARALGRTEPPPVRESDETVGLAAKLHVPTVGLDDLADDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY26</accession>
    <name>V6DY26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C467_09596</name>
        <name evidence="4" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078157.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118604at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="36"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="200" mass="21549" checksum="1E499AF44916480E" modified="2014-02-19" version="1">MTDHSPSDTRADPHAAADRTESPTDGSEIADREPTTVLHVEPNVRSAELLEAFARRHTGRIRVRSVDCAADALDAVDAGVEIDGERVAVDCVVTEQRLPDGTGVELAERLRETDPRLPVVFYTTCPSEEGEAAAFGAGADAYFEKGSDRGRYDAILDRIRALVDERRNREKGAHEGGAEAEVASTTRASGSSEDAVRSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY29</accession>
    <name>V6DY29_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4237" checksum="5F9A03E8CE3068BF" modified="2014-02-19" version="1">MMLGIQKPILSQNTVSFGVSIPLDLSRLTAYRLGRSTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY31</accession>
    <name>V6DY31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_09167</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078161.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113499at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021414">
        <property type="entry name" value="DUF3054"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11255">
        <property type="entry name" value="DUF3054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="14305" checksum="BDAD85D75FD83D1A" modified="2014-02-19" version="1">MDAPPFLAARLDRDAAPLAVGDVIALLALLTVGTLNHTSVEFLTANPLYLPEVYAPFLIAWVLIAPLVGAYSAGAAETAKSSVPLVVRSWIPAAVVGLALRAFVFRGGAELSFAAVMLVLGSLALGGWRALYFRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY34</accession>
    <name>V6DY34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_79</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4395" checksum="2576B62D0037814F" modified="2014-02-19" version="1">MVYSCLIVISYQGSIYAVFIYSPMCSLYVLTGTGTEPINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY35</accession>
    <name>V6DY35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide-binding protein, PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C496_16542</name>
        <name evidence="2" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077735.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="97956at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10130">
        <property type="entry name" value="PIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="138" mass="15223" checksum="26B6B31F8390D64D" modified="2014-02-19" version="1">MKLVVDANVVISALIADSKTRELIVTLEPDLLTPAFVRDEIGNYRGLIVEKSGMEPDRVAQFVDLLFRYIDIVPADDFYPAIDRADDAIGDTDPDDVLYLACAIAAGAAIWSDDTDFEEQNLVETYSTSDVIGSFETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY40</accession>
    <name>V6DY40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4844" checksum="BFF16DFE813EBA65" modified="2014-02-19" version="1">MAKATDSKVPPRLSRECPHTCGALENYDIRGSVEILFFRHILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY41</accession>
    <name>V6DY41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_09516</name>
        <name evidence="7" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078168.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41167at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038978">
        <property type="entry name" value="MJ0935"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42198">
        <property type="entry name" value="PTHR42198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="166"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="301" mass="33659" checksum="11A860AA8A9F1C50" modified="2014-02-19" version="1">MSKVERRVRSLVREDGEMRDAIETVLDNASGGEVRWVDVRDKISSGQWGRLIEKEILVDGEEGFALADRDEIEAGLEDDDSGGSDVETPETTSWSKWDKLAGLATVGAFVGYAVGPVRNAIAGGIDVVLGPLLNVVPFYVVIMVIALGTGLYSTLLRAGLMDMEKMAMYQDRMKDIQERRKEAEERDDDEALDEIQEEQMEAMGDQLGMFKEQFRPMVWIMFLTIPAFLWMFWVIGYRGSTAEYPAVAAQELVVPLAGTVTWDTGIVGPIQMWILWYFLCSMAFTQIVQKSLNIEMSPSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY44</accession>
    <name>V6DY44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_04514</name>
        <name evidence="2" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077738.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000012.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91336at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15615" checksum="2F31C2130444CF5A" modified="2014-02-19" version="1">MSYDPAIVGRYGKLVELWATDHYPLTLDYPVVDGLKFDATDRGGRPWDVKGSMVNGVRPTFKFWEDQHETLADADGGYALVWYRAEGREITIVSSRTVRARDLEITNWTNPGKTHHRSHSREAQLHSGQLQLCNKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY45</accession>
    <name>V6DY45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05386</name>
        <name evidence="2" type="ORF">BN903_89</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="134" mass="14712" checksum="4265BD6AFEB45A0C" modified="2014-02-19" version="1">MIARPVDRVRMPSRSAELVIETWQVRERSLPRVPPDGWETIDRLREAVCLAVACAVEGVEDIESFEGPAAERERFEATVTADSIGHEHVRIASPTSAGSSTDDGADPSELSDARGEGFDETTEQFDLDDALDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY46</accession>
    <name>V6DY46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_09082</name>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000019">
        <property type="protein sequence ID" value="CDK40806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078172.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000019.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121369at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7995" checksum="36D1BD974D4864EE" modified="2014-02-19" version="1">MSTDEPSVPIVCDECETETRVPLDDLADALDKHNAQKHDGDEVAEVDPAIKDRLADLVAEDLGLFDEESTEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DY49</accession>
    <name>V6DY49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000012">
        <property type="protein sequence ID" value="CDK40298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5116" checksum="577C56E928092B81" modified="2014-02-19" version="1">MTAGGVRIGVESETGRESGVTGVGPIFPVDIRGSKFIKGIALSTSNQQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYP3</accession>
    <name>V6DYP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-tyrosine phosphatase, low molecular weight</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_01967</name>
        <name evidence="2" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="127" mass="14091" checksum="883754A0F22990BC" modified="2014-02-19" version="1">MAAAFAERERDRRNAGDRIEIVTGGTRPADRVHEVVVEAVAEVDVDVSDRTPREVTPDELRAVDLVVTMGCSASDVCPATWNGENRDWGLDDPHERPIEAVREIRDEIEARVVALFDELLPETPSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYP4</accession>
    <name>V6DYP4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpl1P</name>
        <name evidence="6" type="synonym">rpl1</name>
        <name evidence="8" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds directly to 23S rRNA. Probably involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077888.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70269at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_A">
        <property type="entry name" value="Ribosomal_L1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023669">
        <property type="entry name" value="Ribosomal_L1_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK40488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="212" mass="23413" checksum="716CCE79CDE96EED" modified="2014-02-19" version="1">MADTIQEAVTLALDDAPERNFRETVDIAINLRDLDLNDPSNRIDESIVLPAGTGQETQIVVFAEGETAVRAEEVADEVLDSDDLEDLGDDDDRAKDLADDTDFFVAEANLMQDIGRYLGTVLGPRGKMPTPLQPDDDVVDTVNRMKNTVQLRSRDRRTFHTRVGAEDMSADDISDNIDVIIRRLEADLEKGPLNIDGIYVKTTMGPAKEVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYP8</accession>
    <name>V6DYP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AsnC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_07497</name>
        <name evidence="2" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078346.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84413at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="161" mass="17497" checksum="43385E1181E02410" modified="2014-02-19" version="1">MDNGSIDDVDRAILYALQEDARNTSSGDIAERTGTSDSTVRKRIGRLESDGVIKGYSASVDYQRSGYPLRMLLYCTASIPERGERIPEILDIDGVVSVQELVTGEENLLVTVVGESDNDITPVAQELLDMGVTVADEVLVRTHETTPFGRFDAGRDDDADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ14</accession>
    <name>V6DZ14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C472_08906</name>
        <name evidence="8" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078456.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000034.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="82991at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="16"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK41111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="251" mass="26306" checksum="DC56E7A3F3248285" modified="2014-02-19" version="1">MTRLGRIRTEAVAAARSFTRRRTAVFFTFFFPVILVVIFGALIRTQPTGGGLFAEPAGYYIPGYLAVVVLFTPLSRVGSEIARHRDGGRFEKLATTPLSRAEWLLAHTLVNVAIIGAASLLILGLVLAVTDATLIVSPALAALPAFVAVAVALFCGLGAVLGAVADSQDGVIAASNTVALPLLFLSETFVTPSLLPEWFLPAVAASPLTYFARGTRAITYEGGEWAGDLLVLTALAAGFLAVGAYAVPRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ15</accession>
    <name>V6DZ15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8191" checksum="23255E251F944C92" modified="2014-02-19" version="1">MDRTTDRHDGSPRVPTGRVPAVSPTGPGTGVAVPTSVVGSDRSPLSEARDPSRSPFFVSAPVDGSVAVRTPVRPATRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ16</accession>
    <name>V6DZ16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_08826</name>
        <name evidence="3" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="112" mass="12327" checksum="DF9AB98CD704DE7F" modified="2014-02-19" version="1">MVLIGVSVVFSVVLGIIALITRLVQLAVLAGLVYVAYKAGSWLLGDGDSPSVDSIGGRTSSTSIDAAESRQDRIRQQYVEGQISEAEFERRIADELETEELDDIDRELERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ18</accession>
    <name>V6DZ18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase (TCE33)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C471_10185</name>
        <name evidence="5" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="DUF772" evidence="4">
        <location>
            <begin position="72"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="3">
        <location>
            <begin position="336"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="546" mass="63398" checksum="723CD5FC08EFFF2B" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQA1</accession>
    <name>V6DQA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_12306</name>
        <name evidence="1" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004598519.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38950451"/>
    <dbReference type="GeneID" id="55595920"/>
    <dbReference type="GeneID" id="65213152"/>
    <dbReference type="OrthoDB" id="115424at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002753">
        <property type="entry name" value="UPF0058"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036519">
        <property type="entry name" value="UPF0058_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42203">
        <property type="entry name" value="PTHR42203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01893">
        <property type="entry name" value="UPF0058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140371">
        <property type="entry name" value="SSF140371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="8693" checksum="A311E8E9B38E8FE1" modified="2014-02-19" version="1">MKKQELIHLHGLLAEVRKQCEFWDDDVDLEAYEELGVKPTSIHKSKTDHKAAVFKLTEGITEPMESSESEPLAPTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB0</accession>
    <name>V6DUB0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C470_01163</name>
        <name evidence="8" type="ORF">BN903_102</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="4"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076567.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="85944at2157"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="PTHR21039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="7">
        <location>
            <begin position="3"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="29161" checksum="68A5EE6C9A34A3CF" modified="2014-02-19" version="1">MYDYHAHTNYSDGAFLRWMVEAAADAGLDGIGFADHCNVSPEPNAERHKRAFGFNLDLTYERRREAIEAVRENAAVEVYDAAEMDYDPDHETPIAEFLDDAGFDYAVGSVHDLDGANVHVRSHFADKPASERRALVDRYFEKLVALVESELFAIAAHPDLIERNPHLRGFATEDHYAAVVDAFRDSRTVPEVNAGRLLDDYGEFHPAPAFLDRLVDAGVEVTVGTDSHEPDEIAPRLREIETELDRRGVEPVRLDGIVADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC2</accession>
    <name>V6DUC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I protein</fullName>
            <ecNumber evidence="2">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_03608</name>
        <name evidence="2" type="ORF">BN903_155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_IV" evidence="1">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="84" mass="8986" checksum="FB70781DFC070C50" modified="2014-02-19" version="1">MSVSCPDDAKESVMDRLETVLPGAFPDAAVDTDHGVRLEFDDASWTLVRPSGTEPYVRVYAESDDVDALVADVEDVVEDAVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC3</accession>
    <name>V6DUC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_00535</name>
        <name evidence="6" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077361.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="21317at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="PTHR43127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="61"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="292"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="369" mass="40873" checksum="8BC60E4D990D08B6" modified="2014-02-19" version="1">MGLEEEIEDLREEIAETPYNKSTEAHIGRLKAKLAEKKEKLENQSSAGGGHGYAVEKHGDATVALVGFPSVGKSTLINALTNADSEVGSYEFTTLDVNPGMLKYRGANIQILDVPGLIEGAAGGRGGGKEVLSVVRTADLVVFMLSVFEIEQYDRLREELYATNIRLDTEPPNINIRKTHKDGLGVTMSDEVSLDEETVKQVLREYGYVNAKVTIPHDLTIDELVDAVMDNREYLPSMVTVNKADLIDKSYLPTVKEELRERDLDPDDVLFISAEKGLGLDGLKERLWEELGVIRIYMDKPGRGVDYEEPLILFEGDTVGDACTKIGGEFDERFKFARVSGESAKHDDQQVGKSHELADEDVLRIVARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC4</accession>
    <name>V6DUC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4295" checksum="75D48664EF5D3626" modified="2014-02-19" version="1">MIGADLRLAFSSRRGNCVENGNDERRRSGQSATAATIPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC6</accession>
    <name>V6DUC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="95" mass="10673" checksum="71BA67BD52CFB181" modified="2014-02-19" version="1">MPDATIVPEFISITTEPITKQTTIPTDTHRSDRIRIIAKEPRMPEQSLSGQRGVERVDPVPAKRRLSHRGISHSGRSLISDLRSRKLPIERIIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC7</accession>
    <name>V6DUC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_14069</name>
        <name evidence="3" type="ORF">BN903_159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="22419" checksum="CDFD0CC9F5AE6A39" modified="2014-02-19" version="1">MDLAAFLNPFTVAGGLLLLASTGLAAVTYTASDLRGGLDLRAVDAVIAAERSEGSWLGGDETPTSDAEFDERLLRSYAEWIDYNARVTAVNDLLATVTVLLIFVAFVYVIAGVVVGAAGLSATESWVSFVVLTVFSTAFTWISAHMDHLGPETTHPAASFAGIPLSKGGDRRQAWSSLRAMLGRAPTEAEELGVATTEPKVDEGGAGDVEGPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC8</accession>
    <name>V6DUC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HhH-GPD family protein</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_02078</name>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15501" checksum="62267422BE91699D" modified="2014-02-19" version="1">MAGLPDQKAARIQRALAAIREETGGAYSLAFLDAMATDDAKAWLTEIKGVGPKTASVVLNFHFGKPTMAVDTHVERVSKRFGLVPGSASNQRAHEVLDEQIPDELIYPLHVLLIRHGREFCSARSPDCDNPVCETYCDCEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD1</accession>
    <name>V6DUD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_05888</name>
        <name evidence="3" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077322.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104239at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="75"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="128" mass="13697" checksum="D9716C362DC6D4F6" modified="2014-02-19" version="1">MNDVPVERLMSTDLTTIERGAAAADAAKRMRETDVSSILVVETDGTLAGLITATDFVTLVRDNDPKDRTPVEAFMTTDVVTVSRDDTVAELAEPTAHGYTHLPVTDDAGKPIGMVSTTDLTAYLSRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD2</accession>
    <name>V6DUD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylosuccinate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_00675</name>
        <name evidence="2" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006188">
        <property type="term" value="P:IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASL_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="87" mass="9679" checksum="BB937971A0504359" modified="2014-02-19" version="1">MREELDATPEVIGEAVQTILRREGDTEAYERVKALSRGRSVTLDDFRELFDDLDVDDAVRAELKALTPASYTGFADELVDEVDGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD3</accession>
    <name>V6DUD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription regulator-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C469_04312</name>
        <name evidence="2" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077365.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="122167at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7255" checksum="A1C230D79C859739" modified="2014-02-19" version="1">MRNDLSDRRAETGESQADLAAAVGVTRQTINAIERERYDPSLELAFDLAAHFDCRIEDLFDPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD4</accession>
    <name>V6DUD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="82" mass="8770" checksum="BDD3239B04DD9A7C" modified="2014-02-19" version="1">MLNDSCSPPDQTPVISRLLAPPSPPSPPSPPSDPPPEQPASATLPSTDAVPVVFSTPRRVVQDRSSDMSFPSFGPNYFKFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD6</accession>
    <name>V6DUD6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription elongation factor Spt5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplX</name>
        <name evidence="3" type="synonym">spt5</name>
        <name evidence="6" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Spt5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077326.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91936at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00950">
        <property type="entry name" value="Spt5_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011590">
        <property type="entry name" value="Spt5_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00405">
        <property type="entry name" value="KOW_elon_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NGN" evidence="4">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="150" mass="16292" checksum="FE014EC3C92E4749" modified="2014-02-19" version="1">MPIYSVKTTASQERTVADMLAEKEMPEIQAVIAPDQLTSYVMVEATDGTVFERILDEIPHANGVIQGGDGPAESPFSEVEHFLSPTPDVEGIAEGDIVELIAGPFKGEKARVQRIDEGKDQVTVELYGATVPIPVTVRGDQIRVLDSEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD7</accession>
    <name>V6DUD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_15801</name>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077348.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112562at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036825">
        <property type="entry name" value="MTH865-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024093">
        <property type="entry name" value="Uncharacterised_MTH865"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07747">
        <property type="entry name" value="MTH865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69025">
        <property type="entry name" value="SSF69025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9196" checksum="9F7EF4C95EA062A4" modified="2014-02-19" version="1">MSDVRAELREQFLEAFGGADFPVENQMDLVPALPDGPATKFEAGDVSLTAMEMAAKLGSEQEFPYDTAEELVDDILDGLEAKGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD8</accession>
    <name>V6DUD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_13118</name>
        <name evidence="1" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077372.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="87054at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043811">
        <property type="entry name" value="DUF5793"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19106">
        <property type="entry name" value="DUF5793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="157" mass="17354" checksum="BA0C1A40B51565C5" modified="2014-02-19" version="1">MRRDCFDLTVDGVGDGVDSRSPPLVRIDFHGPEELLRDRLSGGESGGDDDLLTADEIDVAFRLREPLDEADEPEGVVGVTNRYTGDFVLELNETATDVLPFIHAARDATEDGDAQYRVEIDVEGERLVAYDKDTFLVYDHEGNLLRSESLIPSGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUD9</accession>
    <name>V6DUD9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="3">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="3">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C463_07192</name>
        <name evidence="3" type="synonym">sucD</name>
        <name evidence="8" type="ORF">BN903_132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetate + ATP + CoA = acetyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15081"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076589.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37867at2157"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="3">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="3">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="3 4">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="289" mass="29616" checksum="10F046EC63D1BF00" modified="2014-02-19" version="1">MSIFVDDDTRVVVQGITGGEGKFHAGQMIEYGTNVVAGAVPGKGGQEVDGVPVYDTVDEAVEAEDADASVIFVPPAFAADAIFESLDTDLDLAVAITEGIPTQDMAKVNKRLTETDTRLIGPNCPGIITPGEAKLGILPGNIFSDGNVGLVSRSGTLTYQVVDNLTERGLGQSTAIGIGGDPIIGTSFIDALEAFEADPDTDAVVMCGEIGGEDEEQAAKFIGEHMDTPVAGFIAGRTAPPGKRMGHAGAIVSGSGTGTAQSKIDALNDAGVPVGDTPEEVADHVEDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUE1</accession>
    <name>V6DUE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05843</name>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077330.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130442at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="6568" checksum="3790BD4C5CBF84AD" modified="2014-02-19" version="1">MEFDLPRAAAILVLIVAIGAGGLIGAGMMPLQTTLMMVVPSMLVFGAVAFALGVKHGEFRSAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUE2</accession>
    <name>V6DUE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3781" checksum="1F9A214671DA5390" modified="2014-02-19" version="1">MFSSIVGCSALQPTSQPTPSRSSDAGVSNLSKASLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUE3</accession>
    <name>V6DUE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5464" checksum="472CB935E9AAD8CC" modified="2014-02-19" version="1">MTGRSRAARPSPGTITSTLPLSSSQISPRATSKSVTRGFRAETVTRWCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUE6</accession>
    <name>V6DUE6_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
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            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077333.1">
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    </dbReference>
    <dbReference type="OrthoDB" id="83653at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="169" mass="18650" checksum="6D3903B1E6900765" modified="2014-02-19" version="1">MERTPDGTPVGVDDPYEVAGVCDHLTDDGRCRFALTRASDDPEFSADRRAEGYDCHVGADGEWRACPHYRSTTDAKACVRCGIGDVRLAHENARPLVEEHHLSYDGDDAHEITVGLCRWCHAKVHGSVARIDDDASPDPEAIAERETRKARQQEELSFGTAAERVDDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUE7</accession>
    <name>V6DUE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="1 2" key="2">
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                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="CDK39844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8388" checksum="25BF0F5836201040" modified="2014-02-19" version="1">MDLKKDNHYIILSLPESYTTPLATHRFGVLLISRSCFGPLRPFYHGLEYNPSRVELSYLRGISRHIRSPSDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUE8</accession>
    <name>V6DUE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
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        <lineage>
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            <taxon>Halorubraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="9341" checksum="BCE2E383F36F890E" modified="2014-02-19" version="1">MTPLTLAFVTNDSPPNAVPPSANPIPRRRSCSTSSISCSLILLDSSSQFIYNHSWVHGSGSAAYRSCFALLNYYPSDIFLPETSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF0</accession>
    <name>V6DUF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Halorubrum</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7368" checksum="A1C03BF44AC955F9" modified="2014-02-19" version="1">MLPRWLKNQSSLTPADCGEEGPIDRAVRAGKHTVGHNSVATFDGSRESVLEPRGNAQPEYPLRGILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF1</accession>
    <name>V6DUF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5784" checksum="510E51975D51BE00" modified="2014-02-19" version="1">MSDDYDYSRSRRSWSQSAYQVYSGGSNPWRGSILRPLTYLLIALFSLYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF3</accession>
    <name>V6DUF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_0986</name>
        <name evidence="2" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="348" mass="37611" checksum="22DC9C2F6CE5D600" modified="2014-02-19" version="1">MTRAQYYQSPGRNGGDIMNDSAVEGGRRGTDVTVSTLLGDDHETFESALSGERAGPVAVVGDPFSGRESVLERAERDLDATRVSLDPGDGIDEIRARINGGPVVIADCQHLYERRIDGFEELSAFLDDLAGLDSTVVTGWNRYAWAYLTAVQGLDREFPVTVEVQPLPADRIAELVLGRYDTMPEFVADDPDRGGLIATTRHEIGWRDWSVSVPIPTLSPVAVRDLFSDGDLDPKDLTFGRLAAVSNGNVGVATAIWETRHGAEVRPSDIAVPASDSDLTREEAFCLRIVLSKERVARSELSEIVDGLDRIIRRLSADGLVTVGDGIVELDPAAVPVAATTTERGQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF4</accession>
    <name>V6DUF4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NJ7G_4320</name>
        <name evidence="7" type="ORF">BN903_123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076864.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58376at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="76"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="6">
        <location>
            <begin position="330"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="88"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="425" mass="47852" checksum="F5BF7D98A7BC632A" modified="2014-02-19" version="1">MAEEPSQLSDFDGRYEDPADDPLFDFDEDDPDRANIFARKELLKVGHVPESGRIVGRDGEIKAVAAELRPIVRGDPPNNVIIYGKTGTGKSLVARHVTERARRAAESNGVSVGTVYVDCAQHNTQTRVARTVTRSLNETEETDFDIPRAGIGSGEYYDYLWEILDTAYESVIIILDEVDRLDDDDILMQLSRARESGKADCHLGVIAVSNKIEYRDQLNERVKSSLREEEFVFQPYDANQLREIMKHRRDAFHDSVLSDDVIPLTAALAAQEHGDARKAIEILRHAGELAERENVDTVVEEHVRDAQEWAEIDRFEELLRGSTTQVKFILYSLALLTEENPNKDGFSTNNVYERYKAATEKADAKTLSEHRVYELLKEQAFLGVAESTRTGGGRGEGSYLEHRLVQDTGIVLKSVLRDSRLEDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF5</accession>
    <name>V6DUF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05561</name>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077342.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116457at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018652">
        <property type="entry name" value="DUF2082_NA-bd_Znr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09855">
        <property type="entry name" value="zinc_ribbon_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="12050" checksum="CF1089919353DC4F" modified="2014-02-19" version="1">MPSQNDETEYSVFDDDERDDRRDGRDGSAERGRDAQTDDRPASLGGDGEDGCPKCGGIETETDEIATSGTGLTKMFDVQNRRFLVVSCADCGYSELYKGQSSGDAIDFFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF6</accession>
    <name>V6DUF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="117" mass="13508" checksum="05380A75F235D469" modified="2014-02-19" version="1">MVPADRRGRDLAHALDALGGPRVVADHVARAVDPVDRGHVVEDRLQRREVRVDVRDETDLHRRRVRLAGGNRLWREVRRGTERIQVRTLGGQSTRKSRKRLSAVLWRVPPSGRHRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF7</accession>
    <name>V6DUF7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hbor_35660</name>
        <name evidence="1" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4822" checksum="BCBE7D17B7395C17" modified="2014-02-19" version="1">MYGDFEQEQVLHRGEVRVLPNGWVALPTDRLLSPEAVHHIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUF9</accession>
    <name>V6DUF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_15679</name>
        <name evidence="2" type="ORF">BN903_128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076868.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="112736at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12947" checksum="85FB26FAE4D8C966" modified="2014-02-19" version="1">MEQPSPPTSLPKYLAEGLPKQDTETLREVQRYIEALIKYRDQSVAAEELPETAEPVDEPDNTEKGTVVKEKVTCGDDSCKCASGNPADMHGPYLYRYYRENGTMKSEYVGKPRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG0</accession>
    <name>V6DUG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gatA</name>
        <name evidence="2" type="ORF">BN903_98</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="216" mass="23535" checksum="7127790956AA7EEC" modified="2014-02-19" version="1">MTVGVPTELFEGADERVVETVEAAIDDLEAQGAETTEISLPSVEHAVQAYYVIAMAEASSNLARFDGVRYGHRSESDGNWNESFAETREEGFGAEVKRRILLGTYALSAGYHDKYYEKAQDARAWVRQDFEEAFEDVDVIASPTMPVLPFELGESLDDPLRMYLADANTTPVNLANLPAISVPAGEADGLPVGLQLVGAKFDEETIVRAASAVEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG1</accession>
    <name>V6DUG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M42 family protein</fullName>
            <ecNumber evidence="9">3.4.11.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C467_02233</name>
        <name evidence="9" type="ORF">BN903_35</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.15" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077347.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27966at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="352" mass="37779" checksum="14D5ECBEC938F8A9" modified="2014-02-19" version="1">MAHEFDFEFDLLRELTEARGVPGYEDDVREVVRREFADRVDRVRTDAMGNVVGTIEGDADYSVAVAAHMDEIGFMIRHVTDDGFVQVDPLGGFDARVLRAQRVTVHGDEDLTGVIGSVPPHTLTEEQQETDDEVKDVFIDLGRDAEAVDDLVSVGDLVTLDQTTTRMGDRITGKALDDRICLFAMLEAADRIEEPDATIHFAATVQEEVGIRGATALGVDIDPNLAIALDVTVANDVPQIGDEADAVTELGDGAAVKLKDSSVITSPKVHGRLTDVAEAADIDHQHEVLPAGGTDTAGFQNTAGAKPVGAISIPTRYLHTVTETADGGDVEATIDLLTSFLESETGEHDYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG2</accession>
    <name>V6DUG2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase zinc-binding domain protein</fullName>
            <ecNumber evidence="3">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_05391</name>
        <name evidence="3" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077363.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="33975at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="19"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="340" mass="36229" checksum="BC48E034FF94097F" modified="2014-02-19" version="1">MTNTNREWLLAERPEGEPDTDSFELRETDVPTPDPGELLVRTRFLSVDPYMRGRMRDVESYAEPWDVGDALKGGIVGEVVESGSDAYDAGDLVTGEGKWADYATLDADDVAPVDPTVADPEAYLGVLGMPGRTAYFGLLEVGQPKPGDTVVVSGAAGAVGSVVGQIAKRNGCRVVGFAGSDEKTDWLTDDLGFDAAINYKATDDYRAALDEAAPDGVDVYFDNVGGPITDAVFTQLNLDARVAVCGQIAHYNDEGVPTGPRKLPQIIPVRARIEGLLVGDFATRFGEASERLGGWVATGDLKHRETVVEGLENAPDAFLGLFSGDNIGKQVVRVSSADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG3</accession>
    <name>V6DUG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_01356</name>
        <name evidence="2" type="ORF">BN903_152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076606.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="164" mass="17252" checksum="6A9EC3969592C51A" modified="2014-02-19" version="1">MREGPGGTDRAVSVTVGYVMTLAVSTLLLSGLFVAGGSFVETERERAAQGELTVVGERIAADLGTVDRVASTASPPRENLTVDRPLTLPDRVSGTGYRIRIEATGSAGTIALESEQADATVEVPFRTSEGITVRNATVRGGDLRIYWDAPSGVDDEGEVVVSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG4</accession>
    <name>V6DUG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_14829</name>
        <name evidence="2" type="ORF">BN903_133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076873.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118104at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8365" checksum="8F3559FF05394129" modified="2014-02-19" version="1">MENSADSNGSDDAFPPEKRLEAPNYRLIKAGIATISDMETLRECVAYENAHQNRTQILRRLQWKAEELRESEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG5</accession>
    <name>V6DUG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="5024" checksum="7AF4725786A545C0" modified="2014-02-19" version="1">MESRTPYNGRKHPYKDEERGPSIHTVICLLVRHESFGLVNNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-02-10" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG6</accession>
    <name>V6DUG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl-CoA mutase, large subunit</fullName>
            <ecNumber evidence="2">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12966</name>
        <name evidence="2" type="ORF">BN903_103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077392.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8357at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="1">
        <location>
            <begin position="38"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="566" mass="62971" checksum="DF8E3BF6DC949B19" modified="2014-02-19" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG7</accession>
    <name>V6DUG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4859" checksum="CC57927F7B73AD9F" modified="2014-02-19" version="1">MVSLGRSPSVFTTPRTRFRQRRLRSRLSPMDLRRCVKSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUG9</accession>
    <name>V6DUG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ArsR family transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C489_19066</name>
        <name evidence="1" type="ORF">BN903_138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076876.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115195at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="13142" checksum="CD663429E2A010C0" modified="2014-02-19" version="1">MGQSDRLNEITQLLGDKCVQTILKETSQEPMSAAELNEACTASRATVYRRLDELTDCDLLVEQTKPDPEGHHHTVYAATLDRVMIDFVDGEFEVTVMTQQRAADRFTNFIEGLYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH5</accession>
    <name>V6DUH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HacjB3_18373</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9365" checksum="9D40F11C5908A4EE" modified="2014-02-19" version="1">MDRDLPLAALCGLLVGFGIYRFLSPGGFVSGATGAVYAGAAYFYFAFDVSLLGTAVQFDDRTDRLGYAIXXXXXXXPVDSGPVLSIARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH6</accession>
    <name>V6DUH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05282</name>
        <name evidence="2" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4754" checksum="0AC57A3B0CA4B1F6" modified="2014-02-19" version="1">MPLISPEIRTAFVLAGIAVLGLYAAYRIVAPLPDGRGVSHETMAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH7</accession>
    <name>V6DUH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05060</name>
        <name evidence="2" type="ORF">BN903_113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077405.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111821at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="12611" checksum="173AF8C08AA5FDE1" modified="2014-02-19" version="1">MTFSPETDADPEEIEQRVETVLADNDVVLFMKGNRLMPQCGYSKRAVELIGQHVEEFETVDVLPALPQYREALEAHSGWETIPQTFVDGEFVGGSDVLAELDERGELAAELGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH8</accession>
    <name>V6DUH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HFX_4085</name>
        <name evidence="1" type="ORF">BN903_147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5419" checksum="8EA1886ED8D39C45" modified="2014-02-19" version="1">MCEYLVPTDGTPEELEQCLTVSVEYFQAHRWTDPVDPGHPFLPGKNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUH9</accession>
    <name>V6DUH9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prefoldin subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GimC subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">pfdA</name>
        <name evidence="8" type="ORF">BN903_167</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterohexamer of two alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the prefoldin alpha subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076623.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105878at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00308">
        <property type="entry name" value="PfdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PTHR12674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00293">
        <property type="entry name" value="TIGR00293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16855" checksum="F7893B461BF95209" modified="2014-02-19" version="1">MGGGQQQLQQLSQELQALDEEIEELEAEIADLREEQADIDDAVEAIETLDTGAAVQVPLGGGAYLRAEVQDIDEVIVSLGGNYSAEQEQDDAIDVLRSKQESLDERIEETEAEVDELESESDELEQQAQQMQQQMQQQQMQQMQAQEEDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI0</accession>
    <name>V6DUI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_05416</name>
        <name evidence="2" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="35"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="20136" checksum="FD130BF4F08EF4CC" modified="2014-02-19" version="1">MRNLRADRDDHHTRPDDVEQYSYDDRFHGFTLAPHVDGLPNEDVLSRLEDADLPLFVHAGREFPPEAVETELLGYDLPLVLGSFGGYPLDAELMNRTLDLLDEHDRVYVDTSAVRYREVLERGVLEHPDRVLFGSGAPDVHPNVGVMEVLTLDVSEDLMARVLAKNPARLVPALAEGADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI1</accession>
    <name>V6DUI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_81</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077378.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="86" mass="10159" checksum="8E023AB54FC42AD9" modified="2014-02-19" version="1">MTDNINIDTEEIEELTEEYVTCGTPKRRREIEIELLEVTLWKALDRENGRAFAEFSEEEMEILSEAIDKEDPDVSRLVRRPFLDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI2</accession>
    <name>V6DUI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_12806</name>
        <name evidence="1" type="ORF">BN903_118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077409.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="111776at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010368">
        <property type="entry name" value="Com_YlbF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023378">
        <property type="entry name" value="YheA/YmcA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06133">
        <property type="entry name" value="Com_YlbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158622">
        <property type="entry name" value="SSF158622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13956" checksum="19B2DBEBB2663F3A" modified="2014-02-19" version="1">MSVEQVSIEDLGRELGERIAETPEYERFEEARAAVQRDEEVQSRIDEFEQLRAEFMQARQSGQATNEGLQRVQEAQDELHSMPVMSEYLDAQDELEDTLEAVNEAISEPLAVDFGGEAGGCCQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI3</accession>
    <name>V6DUI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C473_01869</name>
        <name evidence="1" type="ORF">BN903_153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076886.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99354at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="140" mass="15158" checksum="E46650308D7226B3" modified="2014-02-19" version="1">MTDETADNPFDDCELAPDAILGTHTFEDVLFTDETETPVNALTGKTPAHSQATVEEATEFAASIDTDTPQVALPASVETQIETQSKPYTGAAFFHFKATGSLELHRAYHAAYDSDAFNVDFEADYESGDLTISVDRADES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI4</accession>
    <name>V6DUI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="5015" checksum="B8EC5D50DD29A5CA" modified="2014-02-19" version="1">MGPRVLCLTAYRAAAGRVFNIAIYNLLVHSQIKLVVERATEMDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI5</accession>
    <name>V6DUI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_02108</name>
        <name evidence="2" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGA_cap" evidence="1">
        <location>
            <begin position="44"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="269" mass="28426" checksum="A08CFDCE256152CB" modified="2014-02-19" version="1">MVSRRALLASGVAGATGIAGCAASPSGSDDGAIDADAADGDATRIGFVGDLMLGRSVADRWADAXXXXXXXGLTDQSTAFAATDADPGTAFARLDPSVRETRALVGDVLDRVADLDPDLVVASLHWGANWETEPRAVHERFGRWLVEQGVDVVHGHSAHVLQGVEVYEGRPIIYDAGDFVDDYLDYVDREGVRNKRSALFELVVRDGDLDALDVVPTAIDDETAALADGEVAAWVRDTVAERSEAFGTVVDGTDGELADGRLRVPLGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI6</accession>
    <name>V6DUI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_86</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="4971" checksum="944404D758334161" modified="2014-02-19" version="1">MSIYPPKLVKIKKIPERLTSFRTCIRKYSSHNRLFVNKYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUI7</accession>
    <name>V6DUI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C486_00624</name>
        <name evidence="2" type="ORF">BN903_158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="291" mass="31670" checksum="0B1652726BD52B66" modified="2014-02-19" version="1">MTGRYSDDEALRPIGEATHVPDDRLASSDEPRRQRSESIDSGYPDTPTATETECASCGASIPASQSKCRFCLTNYLGDEAIETSQASDLTLLGIIHLVVESTTFYGAVAKGGAAATLLTANEAEPAVDDYTLIYDLNETLARQVTDRWPSLPDAVQVSSEEGAQLLSAACDRAGWHGRETSERQEQVQTPLYDQRGAGIREETRLKAIVDEANDELWLVPAIALTATTSERDSQSRPSPVPTTDRLECQGCGRATDHQFDTPESIPDETWSGQPIWECRRCGTARYGPAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYJ0</accession>
    <name>V6DYJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5367" checksum="045AC94CBEF19B11" modified="2014-02-19" version="1">MPLGHGETVGSPSPNPRVPVAAAIVSRPRRLPNLTDTRLPTGIINLDRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYK6</accession>
    <name>V6DYK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_65</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4100" checksum="6C57F2C730D4BF50" modified="2014-02-19" version="1">MLPSITGATLNIAIAVIGVDARCGHLSGRRRSGFVWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYK8</accession>
    <name>V6DYK8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">tRNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="9">6.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C472_02369</name>
        <name evidence="9" type="synonym">rtcB</name>
        <name evidence="10" type="ORF">BN903_63</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:68080"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8 9">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the RtcB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077855.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="22545at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="PTHR11118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="6">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="334"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="398"/>
            <end position="401"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="424"/>
            <end position="427"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU371113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="502" mass="54093" checksum="90D073B0FF3417EA" modified="2014-02-19" version="1">MTTREVGGFELRKVREHVWELPREGDMNVPARVLASESLLEEIGGDDTLEQLRNATHLPGIAAPALCMPDGHQGYGFPVGGVGAIDAENGCISPGAVGYDINCGVRMVRTNLTYDDVRGREEELVDALFEAIPSGLGGGGVIGGTADAIEGALERGVEWAVEEGYGIESDLARCEDEGRRPDARPEYVSQKAMDRGRNQMGSLGSGNHFLEVQRVTDVFREDVADEYGLREDGVVVLIHCGSRGLGHQTCNDYLRRIEQEHGDLLDELPDKELAAAPAGSELAEEYYGAMGACINFAWANRQLITHQARETFGEVFDADPIDDLGMELLYDVAHNIAKRETHEIGVDAEGDPAVGDAVVDREERDLYVHRKGATRAFPAGNADVPAVYRDVGQPVIIPGSMGAGSYVLRGGDESMSVSFGSTAHGAGRLMSRTQAKQEFWGGDVQDDLEDGQQIYVKAQSGATIAEEAPGVYKDIDEVIRVSDDLGIGDKVARTFPVCNIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL0</accession>
    <name>V6DYL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chorismate mutase</fullName>
            <ecNumber evidence="3">5.4.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C471_03050</name>
        <name evidence="3" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078314.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116021at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="11304" checksum="865A06BB7D61B7E4" modified="2014-02-19" version="1">MSDTPNTENRSLDELRREIEDIDREIVELIARRTYVADTVAAVKEERDLPTTDEGQEERVMERAGENAEQFDVDANLVKAIFRLLIELNKVEQRESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL2</accession>
    <name>V6DYL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_70</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="59" mass="7129" checksum="D4B0AB9F5D96A6D3" modified="2014-02-19" version="1">MRRSGVKTFRRTTYIHILYVIRSVILQYRRHLEKNILDTTWYVISTFRPAAGQFRSKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL4</accession>
    <name>V6DYL4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PIN_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C473_07869</name>
        <name evidence="5" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077861.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="102178at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="PTHR12814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_6" evidence="4">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16721" checksum="E7507F990D50F374" modified="2014-02-19" version="1">MEVLDSSAFIHEYTTDDDVVSIPAVHEELTGEVALRFDAMEGSGMTVHVPAPEAVDRVRRAAKGSGDAAELSDTDIRLIATALELHATLVTDDYAMQNVAERLDLPVEAIARDGISEEREWRFQCVGCNRTFDENKERCPICGSDLTRKNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL5</accession>
    <name>V6DYL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="57" mass="6107" checksum="22B2C5E40EEE487A" modified="2014-02-19" version="1">MFAAVRSDAERDRSAPAGERADLVRGLDGARSRATETAGLRRVRASGIRPNMLPLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL6</accession>
    <name>V6DYL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase AAA</fullName>
            <ecNumber evidence="3">3.6.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_02479</name>
        <name evidence="3" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_lid_3" evidence="2">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="9992" checksum="CEC2564E40A6A4C5" modified="2014-02-19" version="1">MPEPDREARHKILDVHTREKPLVDGIDLDRLADETEGYSGAEIAALSRAAAMRAIERVADEHGEAANDHADEVGITEADFDAALESVRPETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL7</accession>
    <name>V6DYL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4433" checksum="2827A5DA5763C233" modified="2014-02-19" version="1">MEILFCGGKVSWNSRSVKRAYKAVISCLMLVMGMGLLLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYL9</accession>
    <name>V6DYL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1697</name>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078321.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116056at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13213" checksum="E0D375CFF6B6861F" modified="2014-02-19" version="1">MTDAGSGSVFRADEVRSWGARYWFGLLCSVGVAGINYYVWALTGMPQFLAVAGSFAFGVGLFFTRFWNPALYLVGIVHVIALGVVWVLDGGTYPVIGLVNGAFSVGVLLTASSLFLAEHRAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYM0</accession>
    <name>V6DYM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10998</name>
        <name evidence="2" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7183" checksum="3B3A49BD17FB217B" modified="2014-02-19" version="1">MNCASDAKTDVIAALEDAGVAVADFHTREASLEDLFLAYTEGDAAERDTDASDSTRPDDETAAEEVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYM2</accession>
    <name>V6DYM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4353" checksum="B3CC184831AB9D72" modified="2014-02-19" version="1">MPGVPRGDSKPYRSVDSGWHGRSRAASVPIGGRASTTVRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYM4</accession>
    <name>V6DYM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_14037</name>
        <name evidence="2" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078328.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000023.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61519at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="234" mass="25063" checksum="0344E87E7D3CB967" modified="2014-02-19" version="1">MNAAVVTVGDELLVGDTENTNATWLCDRLDARGVSVRRVTVVPDEVAEIARVVNEYHAEYDAVVVTGGLGPTHDDVTMEAVAAAFGRDIEENEEAAAWLAERGYSGGDLAAETTHLPVDCRPLPNEAGVAPGAVVESVYVLPGVPSEMKAMFESVEGEFSGTRTHVATVDVDEPESELLDRVAELRERFDVRVGSYPGTVVTVKITGESEAEVERAAAWVRDHADAVERESPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYM6</accession>
    <name>V6DYM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="290" mass="33089" checksum="1CAF2BDCB64848DB" modified="2014-02-19" version="1">MTVHFTTYQNLIIHMPDSDSSESGILLKELRRQSEEREERHQERIQILVALSLFAGYITAFFNNLFNNVVLNVATTVLFGVILVFLLYKLILNSHVTNNDLITSDKVDRVFSGLYLFSVVGFAVVAVFIITAEQLNISIQDIGSGTIGSILVASMFLLMIILFTFIGKKQNQNLRNQEKRLREELPAALKLLEMGDMLDSSKRSALIERLEALLEEDKEKIPDLFWFGSLMMAMEPDGFVSLNHSDRSRLLTIVERVARRDKHGRHDEEDLEKIEAIIERAEESERSVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYM8</accession>
    <name>V6DYM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="6259" checksum="D42C4F05CA21C7F3" modified="2014-02-19" version="1">MAVVTADAQSDSSTQVLRKEAFLSRESLYETEVVEALWREAKRNPKTGGLVSLRMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYM9</accession>
    <name>V6DYM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytoplasmic chaperone TorD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_15439</name>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078333.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="92455at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="226" mass="25293" checksum="7CA03BB7622E2F1E" modified="2014-02-19" version="1">MSSTNTEPEADNPASREPADSPDESPVDARVYRILGEQLLSRPDRERVDAVGAWAREWLATAESLPVEIETALGRIADGSEADVEPLRTAYTHLFRGISESDPDPPYESMYVGGGFYSETTTEIRQGYRWAGVDVDTTGSNEPPDHLGLELQFLGELLTMDDTEADADEPDVEDAKWWLLDEHLAEWLPTYMARIQQADPHDYYAGIVELALATVKSHRDRLGERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYN1</accession>
    <name>V6DYN1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHOCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_09038</name>
        <name evidence="3" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077881.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106455at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="2">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="136" mass="15415" checksum="FD3C003CD761395F" modified="2014-02-19" version="1">MTGLARRIAWNLRHRWRRVFALCVVGSGVAAPILSGLWWTLPLVWFFGLVIALPVLHTLVKPIPDDDAGSENATGDPALDALRERYANGEIDEREFERKLDRLLETEDAETVDPGDGDVADRVREGLRREVERIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYN2</accession>
    <name>V6DYN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_06505</name>
        <name evidence="1" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="11048" checksum="DB513711FBA59C3B" modified="2014-02-19" version="1">MKQYVGLSATPDLPEGEGMLFVHGEEAERAYVMRDMAFPIDIVFADANGTVTRIHEAEPEPRPYTRYEGTGRYVLEVPRGWSDRHGVDPGDRLVIDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYN4</accession>
    <name>V6DYN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Nmlp_2052</name>
        <name evidence="9" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078338.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="37712at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK40976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="333" mass="33985" checksum="909019F16E17C2E7" modified="2014-02-19" version="1">MIPPGTEAALLDSWDYFVHLAIVLTPLFIGASFLVGLAQEYLPPERVEEMLRARDHGSGNVLAAGLGAVTPFCSCSTVPVLAGLLGAGAPTGMAFSFLLASPIVNWIAVFLLFGLFGTGVTVAYVTTALLAAIVAGLIIGTLDLDEYIKDVRITAGGREIATDGGAAPSDASKAADAASGCSECGTTATNWTHKERVTAAGEGALSFFRDTLPYIAVGIAIGALIHGAVPAEFLQRIAGPGNPLATPIAALAGAPIYVSLSGMLPIAHSLTEAGIPIGTVIAFVIGGAGISIPNLILLNKLFERRLLAIYATTVVTIGITVGVLFNTVFAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYN6</accession>
    <name>V6DYN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6856" checksum="118C3606C275C854" modified="2014-02-19" version="1">MPVGPASVSLSIRRRYLSRSGVGISLDPASMPPQSRRVRKRKPEEYNRFMAVDGVLEIVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYN8</accession>
    <name>V6DYN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_06485</name>
        <name evidence="7" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077884.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="53481at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="105"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="328" mass="36222" checksum="0F51895E74B9B449" modified="2014-02-19" version="1">MTRNTDTGDDSGDAVTDGGVAEDRKGSGFSPITALNDRFGSDFVGSSQFWLPPFLLVGLFVYGAIIWNFLISLTDFTGFGNPRYGDLDLEMYGRALSESGFVDAAVNTFVLLVGFTLVTLALGLGLAILVDRNIRFENTFRTIYLLPMSLSFVVTAQFWAWMFNFNNGVINIVITSLGLGRVDWIGNPDIVLWAVMFALMWQFAGYAMVVYLAGLRAIPNEHYEAAKVDGASTIRMYWRVIIPQLKGSTISASVVLMVFALKAFDFLYSLVGGYRPPNGADILATKMVREAYANLNWAYASAIAITLFLMTLGIVGPYLYYQYNRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYN9</accession>
    <name>V6DYN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arsenic resistance protein ArsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_07457</name>
        <name evidence="1" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000024">
        <property type="protein sequence ID" value="CDK40981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078340.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000024.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="101440at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010712">
        <property type="entry name" value="Arsenical-R_ArsD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06953">
        <property type="entry name" value="ArsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11974" checksum="48D58C8D2A1AF150" modified="2014-02-19" version="1">MTELTLYEEAMCCSTGVCGPDPDEELVEVSAALDQLEDAFDDLDVSRANMQHNIDQFLETQRIYDRVQENGPSVLPITVVDDEIVAEGEYLSYDELTAAIGEGATPQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYP2</accession>
    <name>V6DYP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10933</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077890.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130379at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="71" mass="7193" checksum="2EF2CAFBEC94CBB2" modified="2014-02-19" version="1">MEIDAELRRQITVSLAAAAVFIVGLVGIGVTFGGSTVLPEAGALALVALLAGFVLLMAGVGTYLMRADDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYP9</accession>
    <name>V6DYP9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_06400</name>
        <name evidence="3" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077894.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100195at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="115" mass="12879" checksum="9CC5C61CEDF29C31" modified="2014-02-19" version="1">MEPVDDWRAAITEAGELTGPIAASIVDEHGDRGQRAIEAVGESRVKQYRDFTVVVGHEDEYVIEDGECDCADATYNLDPDDPSERCWHAIAVDVAEAIDAVDHHDMWYSEVREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYQ0</accession>
    <name>V6DYQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="3736" checksum="44FD6E0FA05E1AF8" modified="2014-02-19" version="1">MSRSERVEGAAAKRLPASTAGGFGGRVRGNDYVVVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYQ3</accession>
    <name>V6DYQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hef nuclease</fullName>
            <ecNumber evidence="2">6.5.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_10843</name>
        <name evidence="2" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="75" mass="8146" checksum="9ACB3F4E3EB77C5B" modified="2014-02-19" version="1">MSVHGEKTTKTRAEQQEYVVSSIADIGPVTARTLLEHFGTVEAVMTAPEDDLLEVDGVGPVTAERIREVVGSEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYQ4</accession>
    <name>V6DYQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK40996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="76" mass="8569" checksum="888D14067C2A5C96" modified="2014-02-19" version="1">MLRPPGCPFESRPATAQHLTPSQPRRRSSASLRTADSLARRSFVVAGGDRSEARATASLIDRHRRRYRYLNIAPNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYQ5</accession>
    <name>V6DYQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_10833</name>
        <name evidence="1" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077900.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000015.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106920at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043830">
        <property type="entry name" value="DUF5807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19123">
        <property type="entry name" value="DUF5807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="146" mass="15739" checksum="EA08F665CBECF0F9" modified="2014-02-19" version="1">MSNLDEFLAGERLDDVVFYVSDAYLDDDSRLRSVGTEVDGGVRLILDGETGRSAFQAGTGMGAMEFAKTAMGAEGEIARSLDDGACPFAAENPDDDHEIRFVFAFAEAQNXEVGGLYAEGDVVHAYAHCTCGESYSHKWVVGDRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYQ8</accession>
    <name>V6DYQ8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fer4_23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_06464</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000025">
        <property type="protein sequence ID" value="CDK41001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041346">
        <property type="entry name" value="DR2241_Fer4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18009">
        <property type="entry name" value="Fer4_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_23" evidence="1">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="14776" checksum="E6F462C598E7B6AF" modified="2014-02-19" version="1">MNWVAEACCDDSQCLKRREWEYDEDEDLDVDGGDGIFPCREPCSVVVSAARKWTRLESEQERTYEFDLTPSEKEQVEAIIDAVADGRTDEIREADTKEGANRYRARFLRAKRFDDDGNLGGVPSESDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYQ9</accession>
    <name>V6DYQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000015">
        <property type="protein sequence ID" value="CDK40505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="51" mass="5969" checksum="3CCFAD413C87FC33" modified="2014-02-19" version="1">MFVAHTSTNFYNRQLRQLMPPSTGSVVPFRRPRRSRLPEACVYGRSGSNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ01</accession>
    <name>V6DZ01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5460" checksum="DFD5DF7717DAC2F3" modified="2014-02-19" version="1">MCDRSITLIHENKATPVGVFTGSRSRVNIRSRRRRISSHRARPTAALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ02</accession>
    <name>V6DZ02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C465_09080</name>
        <name evidence="3" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000031">
        <property type="protein sequence ID" value="CDK41091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010879">
        <property type="entry name" value="DUF1508"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036913">
        <property type="entry name" value="YegP-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07411">
        <property type="entry name" value="DUF1508"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160113">
        <property type="entry name" value="SSF160113"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1508" evidence="2">
        <location>
            <begin position="4"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1508" evidence="2">
        <location>
            <begin position="76"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1508" evidence="2">
        <location>
            <begin position="135"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK41091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="184" mass="19847" checksum="8438CD07794B2ED6" modified="2014-02-19" version="1">MFRDAAGEYRWRLVHENGNVLADSGEGYASRQKAQQGLDSVRSNAGGAGLAFPDDEDAEGRAGDGESKATFEAYEDRGGKWRWRLVHDNGNLIADSGEGYASKSNATDAIERVGEYAPDATTLAAGSAAFEIYEDAAEEWRWRLRHRNGNVLSDSGEGYASRSNAVEAVTRVKANAPGAETVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ03</accession>
    <name>V6DZ03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077980.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7417" checksum="1697F6F7E5DE42CB" modified="2014-02-19" version="1">MNADGKIQTLLFGVSGVVWVGCGLLVGIGISPFMWGLTLILFGYFLSRLVQETKRLADATEKIAERSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ05</accession>
    <name>V6DZ05_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="8">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">tyrS</name>
        <name evidence="11" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000032">
        <property type="protein sequence ID" value="CDK41096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078443.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000032.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="59062at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02008">
        <property type="entry name" value="Tyr_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023684">
        <property type="entry name" value="Tyr-tRNA-ligase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023617">
        <property type="entry name" value="Tyr-tRNA-ligase_arc/euk-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006588">
        <property type="entry name" value="TyrRS_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="193"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="38"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="212"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK41096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="328" mass="36197" checksum="4E0AF0938839617A" modified="2014-02-19" version="1">MDAHELITRNAAEVVTEAEIEALADDPDGKRAYVGYEPSGVLHIGHMLTANKLIDLQEAGFEVTVLLADVHAYLNDKGSFEEIRHTAERMRDQFIAYGLDESNTQFVLGSDFQLDDDYTLDLHALELETTLARAERAMAEISSGDSVKVSQAVYPLMQALDIPYLGVDLAVGGMEQRKVHMLARDVLPSIDREPPTSLHTPLIADLGTGRGKMSSSEGVTISMEDSREDIESKVNDAYCPPTADPEPTDDGVERENPVLQVFEYHVFPRFDSVVVERPEEYGGDLEYDDYETLEAELASGELHPADAKGALAEYLDRLIAPGRQQLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ07</accession>
    <name>V6DZ07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobyrinic acid ac-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_08721</name>
        <name evidence="2" type="ORF">BN903_50</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="209" mass="21531" checksum="91E66AF723468BDC" modified="2014-02-19" version="1">MADTSDGDDIIVASEDEADAETVGDDDEADTEVDDAETADADDAETVDSESAEAEIADTDHDGADSEIADDDEADAESVTDDRGTAGEEDAAVDANTDIDATAESDAETDDGDDPDAIPDADETARVTATERTESDDDIDDELAGSIPFRDDDTGTMNTVLSEEPEDGDDASGESADGETGAESPPDAGDEEDEGDGKDGGFFSRLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ08</accession>
    <name>V6DZ08_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dCTP deaminase</fullName>
            <ecNumber evidence="2">3.5.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Deoxycytidine triphosphate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">dcd</name>
        <name evidence="4" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the deamination of dCTP to dUTP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dCTP + H(+) + H2O = dUTP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="EC" id="3.5.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000033">
        <property type="protein sequence ID" value="CDK41101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078450.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000033.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91282at2157"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010550">
        <property type="entry name" value="dCTP_deam_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06559">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="105"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK41101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="203" mass="21876" checksum="5F548E42E6B663ED" modified="2014-02-19" version="1">MILSDADILDRLAEGDLAIEPLDDVDQQVQPASVDLRLGERFLEFQRTNIPCIHPTEADEVGEYVTETTVPEGDEFILHPGDFVLGTTVERVAIPDNLVAHVEGRSSLGRLAIVVHATAGLCDPGYEGQITLELSNLGTAPVALSPGMRVSQLTFTELKRPADRPYGAERGSKYQGQDGPQASRIGDDPEFAGDKRNAAEGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ09</accession>
    <name>V6DZ09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
            <ecNumber evidence="2">1.2.99.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_04937</name>
        <name evidence="2" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.99.4" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_zinc_N" evidence="1">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="152" mass="16253" checksum="520DE8C377572CCD" modified="2014-02-19" version="1">MGHHEDRLELAAEFGATETVSERGEEAVERIRELTYGGPNHVMECVGAASAMNTAIDVVRPGGQIGYVGVPYGVDDEGLDVFGMFGDNVTLAGGVAPVRAYAEELMSDVLQGTLDPSPIFTETVDLDGVPEGYRMMDEREAIKVLVKPHGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ11</accession>
    <name>V6DZ11_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">V-type ATP synthase subunit F</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">V-ATPase subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">atpF</name>
        <name evidence="7" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077991.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="113093at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00312">
        <property type="entry name" value="ATP_synth_F_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022944">
        <property type="entry name" value="ATPase_V1-cplx_fsu_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="SSF159468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="109" mass="11669" checksum="D5620ACF034B0B9E" modified="2014-02-19" version="1">MSQEIAVVGSPEFTTGFRLAGVRAFENVPDDEKDEKLDDAVERTLDDEGVGIIVMHDDDLDHLSRGTREAVEGSIEPVLVTLGGSGAGSGGLRDQIKRAIGIDLMEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ12</accession>
    <name>V6DZ12_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L40e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">rpl40e</name>
        <name evidence="5" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000034">
        <property type="protein sequence ID" value="CDK41106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078454.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38944915"/>
    <dbReference type="GeneID" id="65214832"/>
    <dbReference type="OrthoDB" id="127293at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00788">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="L40e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_L40e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023657">
        <property type="entry name" value="Ribosomal_L40e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39649">
        <property type="entry name" value="PTHR39649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L40e" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK41106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="49" mass="5721" checksum="67270E76ACDF96FD" modified="2014-02-19" version="1">MAKFDAAERRMLDRQICMRCNARNASEAERCRKCGYTNLRPKATERRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ17</accession>
    <name>V6DZ17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000035">
        <property type="protein sequence ID" value="CDK41116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="70" mass="7346" checksum="FBE800181B19021E" modified="2014-02-19" version="1">MSIASAVIILSGYGLYGIVSLNHPQPDYGLLTGVGTAILYGVPIGITTSTIAYVSRRYVTSRSSVAPEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ19</accession>
    <name>V6DZ19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02599</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000036">
        <property type="protein sequence ID" value="CDK41121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078465.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000036.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125485at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="63" mass="6612" checksum="E499FF437D1C7324" modified="2014-02-19" version="1">MDDGTVSVPDEQYERLAALAAARGVSPETQLARLIDDAYAGLDADSDSPESLPLGVSDCSEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ20</accession>
    <name>V6DZ20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_00756</name>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="347" mass="39696" checksum="DDEB071033E18AB7" modified="2014-02-19" version="1">MTDEPLSLPPGFARELTQLIDAMEALRDALSEEETLTAVQDVTVRRRLSLALYPLKGVRRQLADTEHTPSQVDQEVVTWDDSDQALYHIELRLDRLLEDFSIQGYDHSSQEYSIEQTLKTIRDHIVILQDALSEGSTDDSTLPEQLSSHRYVYADVAGRGIADGRWLEYQLHRALKRWGYRAETRQHLFGLEVDVVAKRKPKQQQPTDWLVAQCKDWTSDTITPSTIFRLCTIAFACRAMPVLCHTTDLTADAEELARHFEVRMFDLDDLERPTLPGPQVYKPTAELNKWPPHYGARDDRGMLPLMFQREPGKRFSYVPGFTPVGMGAEYKPVDEDRDDDTHPAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ22</accession>
    <name>V6DZ22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="9521" checksum="AAC6251A0CA5D603" modified="2014-02-19" version="1">MLCVPASAASGSTEVAARAAKRAGPSSGGAGLEGAAARTKTRDARTAGSERSERLRTVVRESEALSSSRDASGVSNDSERIESSRLGLRRSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ23</accession>
    <name>V6DZ23_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000037">
        <property type="protein sequence ID" value="CDK41126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK41126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6791" checksum="4F283AF1965A83A9" modified="2014-02-19" version="1">MRLVEPRDHVEEVALETCEVVHTTVSTYLSKINKYTVISVSVRPDAPPYHPATDTPVLSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ24</accession>
    <name>V6DZ24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078022.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000017.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="96" mass="10429" checksum="09062AECA672FE3B" modified="2014-02-19" version="1">MGDSETTLLRMNEQGVTTIPSEVREVLDIDGKRAILRVKDIEVAKVTEDPTSESEPEAKDDGNKMPNDVGDRGHIGAKPLIAGLGLIIIFFLITLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ26</accession>
    <name>V6DZ26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_11350</name>
        <name evidence="2" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000038">
        <property type="protein sequence ID" value="CDK41131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078474.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000038.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123023at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK41131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="119" mass="12444" checksum="A0392AC880C89833" modified="2014-02-19" version="1">MLLQTVTPVSVLGTTVLLALFLSVTAHVAARNVLGDVDPRRALYVGPLPAVISVVGNAFDAPAALIVLGALLVDGTMFWWSYEEPRRVVAAMTLIHAVVTTLLAGVLILISVLLASMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ27</accession>
    <name>V6DZ27_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit E</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">V-ATPase subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">atpE</name>
        <name evidence="7" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000016">
        <property type="protein sequence ID" value="CDK40603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077989.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000016.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="93762at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="PTHR45715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="11"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="192" mass="21524" checksum="8580EF1D7C9DCFC9" modified="2014-02-19" version="1">MSLETVVEDVRDEARARAEEIREAAEAEADEIVAEAETDAERIREERLAEVDDQIDQEREQTLSSAKLEAKQERLGARRDVLEDVHDDVEAAIEGLDGDDRRELTEALLDASLAEFDGDEDVAVYTRAEDVELLEDLVADRNAEVDGEVDCLGGVVVESDTSRVRVNNTFDSVLESVWDDELKNISDRLFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DZ28</accession>
    <name>V6DZ28_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1863 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HLRTI_08720</name>
        <name evidence="4" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000017">
        <property type="protein sequence ID" value="CDK40635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036490">
        <property type="entry name" value="MTH538_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52206">
        <property type="entry name" value="SSF52206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1863" evidence="3">
        <location>
            <begin position="6"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="207" mass="23583" checksum="EFCA7680F4BEAEFF" modified="2014-02-19" version="1">MTSKDREAAGFFDAAEQETIKQATDEKIRHWINEQLQGTSVTVVLIGNETAERDWIHYEIKKSIERGNGIVGVKIHSLNDKESNTDFSGTNPLKKFVVEEGDKVRTLSTIFPTYDWKRDNGRENIGKWAEEAAQTAESLSRDQQNSVRRRETISEGLNPDAGTVIFVLIIIAILIDKYTDINLRETIDLSQLQQQNDQSDPFSKHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPR2</accession>
    <name>V6DPR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="10147" checksum="673DA2F89E1B8775" modified="2014-02-19" version="1">MTQDELSTSVDSIHITGSFARGVATPGGSDLDIRIVTAGYVSSTELSDLTERIESEEDPERTPAECDSLDIHATPFELLHSEPSIEIWNGENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPS2</accession>
    <name>V6DPS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076010.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="91" mass="10328" checksum="4F341F53397960F2" modified="2014-02-19" version="1">MSTEDTHHDSSPQRELEPNEVPLSTLDVGDVFSFNDDDPRYELIDMKFLGEHRDNVWAYANAETGEFEGLIRDGACPAHFPEPVVPHDTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPU2</accession>
    <name>V6DPU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076024.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13916" checksum="75C5E946E09650B6" modified="2014-02-19" version="1">MEFFDTRNRLSHWFPRLEPLDIPTIDTQILELEGGSGGEFLKEEEIDPIGIIMTEDPEPVFKFFGHPDFSVITSFVENTDNKQAFLRSDYKSATNLGDGNHIEVNSRGRNREDGHAPAPGSAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ32</accession>
    <name>V6DQ32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_00452</name>
        <name evidence="3" type="ORF">BN903_14</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076205.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="2">
        <location>
            <begin position="10"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="166" mass="18826" checksum="FE22E9B624F4DA7D" modified="2014-02-19" version="1">MPTYRRTTRVPAPIEDVWAFHSTVDGLRELTPDWMRLRIGDVEGPDGSPDPEVLVAGSTIEMSLRPFGIGPRQRWTSRITERDPEGTTPPERSARFVDEMEGGPFRRWEHTHAFYADGDETLLVDAVAYRLPLGPLGDAAGPPAKIGFEGMFRDRHRRTIERFSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ33</accession>
    <name>V6DQ33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_22</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5320" checksum="1822650007369E2B" modified="2014-02-19" version="1">MGDATRIEHDDRCTIPGNRGWEGFDERPAHTRGDSMTTVYTCDPDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ38</accession>
    <name>V6DQ38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_19</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="3982" checksum="1F953E45699E11BC" modified="2014-02-19" version="1">MRVGLVPASSGGVLGHRPASNGRAVAAPIIISVLIASSVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ39</accession>
    <name>V6DQ39_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C463_10895</name>
        <name evidence="6" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076209.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58376at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="54"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="309"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="66"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="400" mass="44464" checksum="58274B6A9AA98764" modified="2014-02-19" version="1">MDAADDLFTREDPIFANKELLEISHLPGEGRIVGRDDEIADLATAVNPAIFGQSPSNVLIYGKTGTGKSLCAKYVSKRLVSTASEEGVTATFAYVDCAQDTTETQAVQTIAEGVNDPEETGINVPDKGLSTSTYYKRLWRILDQRYDVVLILLDEIDKLDDDAILMQLSRAGEAGKITDCKLGVVGISNKIQYKDRMDERVKSSLCEREFVFPPYDANQLREIMQARADAFHDDVLEPSTIPRAAALAAREHGDARKAIDILRYAGEIAQANGEPTVREEFVTQARERAETDRFRELIRGSTPHSRYVLQALALLSLSNGRQDGFRTSRVYEIYENICRQEGSDSLSLRRVRDLLKEHAFLDIIEQSKHSGGSAEGSYTKHQLLEDPSVVKEVLTEDADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ44</accession>
    <name>V6DQ44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5608" checksum="C606081FE4D4F5FD" modified="2014-02-19" version="1">MEKYIPDSRSRDLPTDIVSPRYYRVSTDRSPANRSMKSHDVAQIVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ46</accession>
    <name>V6DQ46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate hydrolase</fullName>
            <ecNumber evidence="2">4.1.1.68</ecNumber>
            <ecNumber evidence="2">5.3.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_12073</name>
        <name evidence="2" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.68" evidence="2"/>
    <dbReference type="EC" id="5.3.3.10" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008704">
        <property type="term" value="F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018800">
        <property type="term" value="F:5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="229" mass="25128" checksum="65360AB1D95EECAD" modified="2014-02-19" version="1">MAGRHVDGTIVADDGRYEVGRDGRLLPPCDPSALYCVGRNYAETLDQMDYERPEEPDFFIKPPTSLLAHGEAIRYPEWTDELTYAGELVAVIGERCRDLEPDEVPEVVRGYTVMNDVDALDQQGRTARKAFDGSAPLGPWIETDVDPTDLDIETTVGGETRQDANTELMLFGPHEIVSYLSKRFTFEPGDCIAFGSPANPGLVEPGERVEITYEGVGTLSNTVVDPGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ48</accession>
    <name>V6DQ48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein Crp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C462_16104</name>
        <name evidence="2" type="ORF">BN903_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076210.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="41689at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012015">
        <property type="entry name" value="UCP_HTH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004955">
        <property type="entry name" value="HTH_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="1">
        <location>
            <begin position="30"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="270" mass="28493" checksum="9A0C8774094C03E9" modified="2014-02-19" version="1">MEPSEDPGEATAPRVLDNRRDATRYRVLVEIAARQPAVSQEEIADVIGVTSQAVSDYVRDLVDGGYVEKRGRGRYEVTKEGVDWIITRTDALSEFVSRVSDDVLGSVDVDAAVAADAVEEGDEVGLVMRDGVLHAVPEGGSATAVVVTGGEAGEAVGVTEFEGVVEYDPGVVTVVPVPAVTEGDPPSSDVITDRAAAADLIAVGGTEAYALATRTGLRPDVRFGSATGVSQAALRGLNVLLLVSTDELSRHTTRLREDGVRYEVRDSLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ52</accession>
    <name>V6DQ52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_37</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4833" checksum="656D0C4901E0D16F" modified="2014-02-19" version="1">MMSDDDDATGGSDGDEGIADGEGTDDDESARDRGPYQSWEGKAHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ53</accession>
    <name>V6DQ53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4161" checksum="6C75E32CC3A1F6FD" modified="2014-02-19" version="1">MLGQGFEPWSSADFRTGADAPRPPKGQHDWPDYTNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ56</accession>
    <name>V6DQ56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_42</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="7423" checksum="B125C66007D6C86E" modified="2014-02-19" version="1">MDLPRFHTPPSGANHLNFDQNIYLGAPPILTVEFGSKRLSDWWIRSWRMRNRPIRSILYRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ59</accession>
    <name>V6DQ59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MoaD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_00045</name>
        <name evidence="1" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076216.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="119587at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010038">
        <property type="entry name" value="MoaD_arc-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01687">
        <property type="entry name" value="moaD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="93" mass="9923" checksum="98231DB02BE06B3F" modified="2014-02-19" version="1">MELELRFFATFREAAGGKTVDAEFADGSTVGDVLRELESEYEGMAGRLIVDGELAPQINVLKNGREVLHLDGLDTPMADGDRLSVFPPVAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ62</accession>
    <name>V6DQ62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="5861" checksum="4B8275F61097D073" modified="2014-02-19" version="1">MGEESQFLILSTPQVFTGANGSRGQPMTIRIDERSGVGGRLVRAGVPTGQEGEIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ66</accession>
    <name>V6DQ66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4630" checksum="FB062A51745ACB71" modified="2014-02-19" version="1">MDRLSEHQNVWIAHGRETRRGRDKIWPWEAVSALRDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ67</accession>
    <name>V6DQ67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_52</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="98" mass="10812" checksum="ED409A7FD0A544E5" modified="2014-02-19" version="1">MCLASHVLVITSYSIHYTKLYESTRAGGRRDGTGGRAVPISTTAAMAAISVVRMAFIAIPDRVQTHLNAASRSAHFRPILPGLTERRRFNDRDRGSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ70</accession>
    <name>V6DQ70_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="100" mass="10460" checksum="7F6D0A29C3AF8483" modified="2014-02-19" version="1">MRSAVTDSAVKPATHAATTSAITKVPTPISFSTVRSRVGARARRSNTQLTSGLTTYRPGRYSAAATTRNSAICAGRPTYFEASPVVTYGAVIPDTPVGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ72</accession>
    <name>V6DQ72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_57</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076224.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="89" mass="9493" checksum="AE3F32B3611A94DE" modified="2014-02-19" version="1">MSDDVTVDVEVEVEVDRDELEIERDDAELIEATYEANGIEIEVEAEVETYGSPDGGSDSDTDGGSDSDTDGGSDSDTDGDDEGGYEDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ75</accession>
    <name>V6DQ75_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="50" mass="5373" checksum="46870F797627A691" modified="2014-02-19" version="1">MSSTARYAPPETQMTRSTRSTLVRSASVAFLGWTGIGYGTPNPRSVRPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ79</accession>
    <name>V6DQ79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_62</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="40" mass="4564" checksum="254D80F7433F9C43" modified="2014-02-19" version="1">MMSTAPRSTGRVHENGRYTPSVRRLSDSCLTEPYMFGDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ83</accession>
    <name>V6DQ83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_00270</name>
        <name evidence="1" type="ORF">BN903_67</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="6108" checksum="C283189EE199E8A7" modified="2014-02-19" version="1">MRLVDTANAVYDLGVDAAPLEAFAEEIRRHYEDLAERIEEREPEGSYDRMYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ85</accession>
    <name>V6DQ85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MscS Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Halar_2029</name>
        <name evidence="8" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334911.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="58511at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDK38384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="300" mass="32556" checksum="4A4F53FDACEA0A3F" modified="2014-02-19" version="1">MTTGILTAATVLRQASEPDPGPEELTVFWPLLVQLGWFLAGFSAVVLIGWLVVQPVLRRAVRRRNRNNPTLQAAVVLYFRLLVVLVGTLVGVALAGYGELLGDSALVISAVALAVGIAAREVIGSLVSGVALVLDPEFNVGDHIKWNGGEGTVQSIALRITRVETAAGELVTIPNTILTAHEITRPYGRGNHRIVQELRVGYESDLDDVLYQLIEVADETEGILTDPPPAAYVDELGDDAVSVRVHYWITDPTRRDVFAVRSAYARAVKDRLEAEGINVSPPAERELSGRIRLSDPSERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ88</accession>
    <name>V6DQ88_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_00507</name>
        <name evidence="6" type="ORF">BN903_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK38326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="278" mass="31650" checksum="39DE0DD58A12E1E8" modified="2014-02-19" version="1">MPIYVALDSADVWASPEAFRLDDGNRPTAVAGVPPNAGDNGQRWGNPLYDWDRLAESRYDWWLDRFRRLFELADVARLDHFLGFVKYWAIPADSDDPADGEWRDGPGRDLFETVERELGEAPFIAEDLGFEEPAMDELMAEFGFPGMRVPQYADWCAEGNEYQPMHYPEGVVGYTSTHDTDTWVGYFEDLPERQRDCFRYNVGSDAEEPAEWAIIDELWASEAILAVTTVQDLLGLGSDARFNEPGTLAGNWEWRVTRGALDDEIADRLWELAGDHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ90</accession>
    <name>V6DQ90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_72</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="81" mass="9472" checksum="4122A185559C3E12" modified="2014-02-19" version="1">MIGLRYVESVNSLLQTPSRRNGWPARVRRDWHQARTHNIRRISAGQTRIDQKERVSAEYENECLSGDYTRGSSTLEIRPLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ93</accession>
    <name>V6DQ93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Adenylate kinase</fullName>
            <ecNumber evidence="1">2.7.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C465_11882</name>
        <name evidence="1" type="ORF">BN903_77</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076241.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="79684at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="184" mass="20102" checksum="2CAF3C526B99EBAF" modified="2014-02-19" version="1">MSVTLVSGVNGVGLSSVCQAVRRGLGDGYKLINFGDAMLEQAAAMGITTERAQLGTLSQTETRRLQRRAGEFVAREAATTNVILSTHLAVETLDGYVQGLPVEVLHDVSPDAFVLVEAEPETILERRRESDRDLDGVTERKIDFEQDLNRSAALQYARDQNAPVQFIENEGELEDAAERLADAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ94</accession>
    <name>V6DQ94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
            <ecNumber evidence="1">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C463_08646</name>
        <name evidence="1" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076198.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67908at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="262" mass="27340" checksum="675FF5133606B185" modified="2014-02-19" version="1">MDLEIAGNAALVTASSSGLGKASATALAREGVDVVINGRDEDRLAEAKAEIESVAEGEVVAQPGDLTDPDDVTALVEATVDEFGGLDHLVTSAGGPPSGAFLETDDEDWEEAYELLVMSVVRLAREAEPHLREGDGGTIVNVTSRSVKEALDSLVLSNSVRMGVIGLEKTLSKEFAPAIRANAVLPGPHETSRIRELVNDAVDRGEYDSYEEGLAEWAGNPLERIGDPMELGNTVAFLSSPKSGFINGTALPIDGGATGANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ97</accession>
    <name>V6DQ97_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_12342</name>
        <name evidence="3" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076237.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18140at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="238"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK38399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="406" mass="44486" checksum="7CA85365CE7ADA42" modified="2014-02-19" version="1">MTRDPGPTPPSERITSLDALRGFALLGILLINVWVFSMPEQTLLNPNVYADAAVYGDLSGANYWAWFAGHVFAQSKFITIFSALFGAGVLLFIESKEEKGQDAVRLHLRRTAVLIGVGLLHAYLLWYGDILVAYGLTGIFLLFVRDLDARQLAGLSGVFLLFLPAVELFAAVSIGGDAIAGQWLPSEAALRQQVATYRGGWLEQMSHRVGSSFQRQTTGFIGQNFWRVGGIMLLGMALYRWGVLTGERSTAFYRRLVAGGVVGVGIVVAGVAYIEANDWSAGAALFWRQFNYVGSLLVAGGYVGAVTLFVRWRGEGILTTALAAVGRTAFTNYLLQTLIATTIFYGHGLGLFGSVTRVEQYGIVAAIWAVQIPLSVLWLRYFRFGPVEWVWRTLTYGEAQPMRLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ99</accession>
    <name>V6DQ99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_00803</name>
        <name evidence="2" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076246.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="125423at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10348" checksum="F01130EDEF9CBF53" modified="2014-02-19" version="1">MGLVGDLKDDVVGLVRDPTDEQKILVIAFIAMAAADRYMYFNDIPFVVRTTAAVGVGFIVMFVVSYLLTGQFVPPDGNVDDDEEQAEYVDELDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ0</accession>
    <name>V6DTZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14464</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="129" mass="13119" checksum="94368DFE4E2AFEA7" modified="2014-02-19" version="1">MGIPFSEAIGTALGAGVTLPILGDLPPAYLPLVAFSGLLGVADSFREPASMALFADEGTDDGGVASSFGIRELVWRPGSVAGPLIAGWLMVEVSMGSVFYVGGAFAITGVLAFLAILVHDHGRAALSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ1</accession>
    <name>V6DTZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="62" mass="7128" checksum="EC2386F029B64D06" modified="2014-02-19" version="1">MTQLQRRYQAIRFELTNTTVDAHPSLVKSNRGARLAEWERLVMGETDRVSLGAMSDLTQKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ3</accession>
    <name>V6DTZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11030</name>
        <name evidence="1" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077247.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="136154at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="150" mass="16894" checksum="512D21FE684E1939" modified="2014-02-19" version="1">MTSNNSDDLNIAQPEDFFVQRDSDDNLQPVTQPLPGVEQEIRVVPMSMGDLNEYGDANGQLNPADLSDEDIAEILNEHWYDVRENDDFDVTAEKVDEDMIGFGLEALIQAILRASGYDMQNALNLENLEMLDQVPEGKLETMMELAESQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ4</accession>
    <name>V6DTZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cellulase</fullName>
            <ecNumber evidence="9">3.4.11.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">C467_14454</name>
        <name evidence="9" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.15" evidence="9"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077217.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27966at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK39616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="351" mass="37097" checksum="5B3DAA206F3295E8" modified="2014-02-19" version="1">MTANATFDFDLLARLTDAPGPVGYEDRVRDVVRDELPAVDAVRSDAMGNVVATVEGSADPDYEVLVAAHMDEIGLIVSHVDDDGFLSVEPLGGWNPDALRGHPVTVHTRDGDYDGVVGINAAHTAAEEAPEEWTLDDAYVFTGLDPDEATEAFGVGDVVTFDSDLREMGECVSGSALDDRAGVYAMLEAARLADPDVTVHYAATVQEEVGLRGAAALRVDVDPDLVVALDGTLEQSYPGVDPSNAITTLGDGVGIKRKDASVIPTAEVVERFESVAETRDIAFQREVSWNIGTDTAALQNAGGARPVGALSIPVRYHHSAVETADARDVEAAVDLLTAFLDSEDGTDYAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ5</accession>
    <name>V6DTZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5717" checksum="40508E075DB7E663" modified="2014-02-19" version="1">MELEARTVDVDERTPAKNRALLIRGRLGDQWWWNCSEKSIRNLRYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ6</accession>
    <name>V6DTZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="68" mass="7880" checksum="393080AB6F160685" modified="2014-02-19" version="1">MNPEDERSEVLVVHNPSGPTSCRRKQTRERWHRTELGLNSATTEASPCGVRSLRPHFPSRERSDKRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ7</accession>
    <name>V6DTZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C481_11005</name>
        <name evidence="3" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077251.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="108" mass="12363" checksum="D08F2826D8AA288A" modified="2014-02-19" version="1">MTNIPTGLLEMSITLIAGVLFTLVGIIYRRLKKRITELEENIAQLESQLLKLKRDMDTAQSWMFGLDEDETNHGIASQISSINKRLTQLIDALHDEDDLEFERDDADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTZ8</accession>
    <name>V6DTZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5719" checksum="496FA144858E24E0" modified="2014-02-19" version="1">MLGDHRYRRVRVRSYKIRGESGSLCRISGTECERLVPRGRERGRRDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA0</accession>
    <name>V6DUA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor IF-2 subunit alpha</fullName>
            <ecNumber evidence="5">2.7.7.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_03479</name>
        <name evidence="5" type="ORF">BN903_130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077287.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="84684at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="PTHR10602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="SSF110993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="SSF116742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="10"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="266" mass="29174" checksum="1CE4D438B169AA80" modified="2014-02-19" version="1">MKYSGWPEPGELVVGDVDEIADFGVFVDLDEYEDKRGLCHISEVASGWIKNVRDHVREGQTVVAKVLEVDESSSQIDLSIKDVNEHQRKETIQDWKNSQKADNWMEIALGEDVDDDRYTAVANALLVEYESLYDAFEAAAISGDEALEDVDVDDDTVDAIVTAARDNVSVPYVDVTGYVDLESAAPDGVDDVRDALAAAEGNGEIPDGVELDVGYVGSPEYRIKVRAPNYKTAESQLEAAAERARESIEAAGGIGGFHRERREDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA1</accession>
    <name>V6DUA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C464_07960</name>
        <name evidence="1" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="425" mass="45328" checksum="F79D07D8D65E4533" modified="2014-02-19" version="1">MPNCATVVSARPQCVPRQKARRSGGPRGVIVSIERESDRTTPTERFARIGCFRPIPGVRNGDHGSNHKTDLSRSCPEFRMPSRSRRALLAAVGTGFAGGLAGCSARLGNLTSQTDPNEFSVGPLYVADGVPLPDGADPQTVDDPAAARVALFPSDGFDRPEPGTALRESTPVVVVGRNAQVLPMDLCAADGRPYGFASDGWGSDTRVAAAVPSEDGLVTHVFEGIEVPGGLAGAVDTVLNPPRTACAVDAELSDRPPGFDEEARTLGPSYVHGRNDVATFTRRDAVRVVSDADGTHVELELRGTIRGGDGTYDADQVRLVASFDDRLRATAPPASETGGLAVRRVAEETGDTVDHRFTQAGDGVRPEFTACQRSLVTAAETPGPFSYVGNARFRWRDQRLIREDDLWHHHTPGQGVWYPDGGRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA2</accession>
    <name>V6DUA2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">pyrB</name>
        <name evidence="9" type="ORF">BN903_92</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer of catalytic and regulatory chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076753.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="51351at2157"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="150"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CDK38798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="313" mass="34627" checksum="FF77DD356F7E8F17" modified="2014-02-19" version="1">MRQDHLITATQLSRDDIETVLDRARAVADDPAAYADRHAGRVLALCFFEPSTRTRMSFDSAAKRLGMNTIDMGDVDSSSVSKGESLSDTVRVIEGYADAIVLRHPSEGAATLAGERVDVPVVNAGDGAGQHPSQTLLDLHTIREDHGLDDLTIGIMGDLKYGRTVHSLAAALTNFDVNQHFISPESLRLPRSVRFDLHETGAQVREHEELEPVLDELDVLYVTRIQKERFPDENEYHRVAGEYQIDADTLADAPDDLTVMHPLPRVDEIAPDVDETDHARYFQQAHNGVPVRMALLDTLMENAEAAEGTEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA4</accession>
    <name>V6DUA4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_03524</name>
        <name evidence="3" type="ORF">BN903_135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077292.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128536at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="146" mass="15032" checksum="C6F58A2F09E835F8" modified="2014-02-19" version="1">MDATATTYLPYALLAMGAYALVSPLMRVATTGPNAIPSDVAVVVSNSLLIVMAVGVIAYTGQGFTTHLASPKLPHVLAAGFFLGVGILALYRSLSLGPVSVVTPIFAMFLVFSSVIGFLFLGESFTLRKGLGIVFAAASVYLVSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA5</accession>
    <name>V6DUA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase GroES domain protein</fullName>
            <ecNumber evidence="6">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C465_11061</name>
        <name evidence="6" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077350.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31525at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="5">
        <location>
            <begin position="30"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="4">
        <location>
            <begin position="183"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK39799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="346" mass="36476" checksum="31B82EAE42308162" modified="2014-02-19" version="1">MEAARLHEYTDDMSEGLTIDEVDRPAATGPDDVIVEVEGAGWCQTDNHIIEGMWAEYVPQELPMTLGHENAGTVVETGDNVDLVSPGDPVICHPVQTCGTCRPCRLGETMYCENDAFNGLTTDGGFAEYLHTSERSVIPLPSGVEPIDIAPHADAGITAYHAAKKAVGELNPGDHAVVIGVGGLGHIGLQCLDAMSAAQITAVDLKDSALDLAEGYGADFLVNPTDDDVAAEIEAITDGTGAAQVLDFVGEDVTTAYAPEITAAGGDHHIIGYGGHVHEPSQALVNGEFSFVGNIVGRYAELQELVALVEQGDVDLHTSRYDLGEINAVAEKLEHREIDGRAVITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA6</accession>
    <name>V6DUA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HTH DNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C473_04809</name>
        <name evidence="4" type="ORF">BN903_97</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076561.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000003.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81770at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="161"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK38803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="222" mass="25238" checksum="FE33513CD08B6B50" modified="2014-02-19" version="1">MKYLRLELRYPPDLMHPMHRLVDESDAVERDVLLQGTILDETADTFLFYVEGDIDVYTDALRAVDRIREYEVTRIDDDGYYVFLTQRRDAVDEAMFDPLQRTGIVVVPPVDFRPSGIVRLTLIGERGPLGDALAELPDRIASDVLRIGEYDWRQDLFDPELTDRQFDALAAAVETGYYDSPRSGTVEEVADRIDAAPSTASEHLRKAESAMMSAFMELRDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA7</accession>
    <name>V6DUA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction protein with CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_02398</name>
        <name evidence="3" type="ORF">BN903_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077323.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83765at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK39767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="124" mass="13329" checksum="7F66555AB4E71656" modified="2014-02-19" version="1">MDLDDRTRVADVMSAPLETIAGDAPLREAARRMRDQDISALVVTTGGGCIVTQSDIVGAIADGRDPAETTVRDVMTEDVETVTPDLMMQEVAAMMTMYGVKHLPVVDDDYVGMVSTTDIAEHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA8</accession>
    <name>V6DUA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenine specific DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HVO_A0237</name>
        <name evidence="2" type="ORF">BN903_140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041635">
        <property type="entry name" value="Type_ISP_LLaBIII_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18135">
        <property type="entry name" value="Type_ISP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Type_ISP_C" evidence="1">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="272" mass="31543" checksum="D6830080A07D5CD5" modified="2014-02-19" version="1">MLAGDNVALALPNRTERTPFDHAFVTDGIMEQSGLSTKEGNHLFPLYLYPNVPDETTSKLPNTTQQTSINSRLISQLSEAYSDEVTPEKVFNYTYAVLYTRPYRLTYSEFMETDYPKIPFPRDEVLFKKFESLGEELVLLHLLDHSNLESPGIKLHTEEGGDGENEVSENTGEYYRHYDEEKQRLYINSDQYFAPVPQDVWEYEIGHRPVVNKWIQNRIGETLSSNDIRKFCRIIRALMETISIQDGLDKSWEAIESNYLTFELKGQQTFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUA9</accession>
    <name>V6DUA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6129" checksum="3525948632671EEC" modified="2014-02-19" version="1">MMCRLPPRHSDTLAALIPRLFQARMCLKNRISTEPVTSILNEPSQNILLFEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB1</accession>
    <name>V6DUB1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Protein transport protein Sec61 gamma subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">secE</name>
        <name evidence="10" type="ORF">BN903_11</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006628863.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="SMR" id="V6DUB1"/>
    <dbReference type="GeneID" id="7401271"/>
    <dbReference type="OrthoDB" id="121918at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="SSF103456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK39772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="58" mass="6176" checksum="0E8AF3DA006E4554" modified="2014-02-19" version="1">MDVPYDLNSYIRVLKLASTPSTDEFLQVSKIAGAGILLIGFIGFLMFAIMSLLPGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB2</accession>
    <name>V6DUB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4910" checksum="4861D67A018E5C1E" modified="2014-02-19" version="1">MRSSGELEAVSFVELRCSILGRKTGSDTFNQDALSSPGCFRRETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB3</accession>
    <name>V6DUB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C462_05034</name>
        <name evidence="1" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077354.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123038at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="8270" checksum="CBF4286D27E32C08" modified="2014-02-19" version="1">MSDAETPEERIDETTTWPDLAIGLYDRLTGRNAEIHYQFEDMTVEVPSGTGDDAEHAEWRIDGGVRVTTSERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB4</accession>
    <name>V6DUB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HQ_3591A</name>
        <name evidence="1" type="ORF">BN903_83</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076839.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000004.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="115780at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="77" mass="8810" checksum="4ED956FDE4C0492E" modified="2014-02-19" version="1">MANSRRPIAPAEEDVLDHLEAYLEELGDTDPLTREMAITYLAEQEIRPADARDIIEQLLLKGYLYEVGDEIRIPPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB5</accession>
    <name>V6DUB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4377" checksum="3845173A1ED21535" modified="2014-02-19" version="1">MTYAWFGPAGQKASAPRRTSVSAARDMRVRVYLRPHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB6</accession>
    <name>V6DUB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenazine biosynthesis protein PhzF family</fullName>
            <ecNumber evidence="1">5.3.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_02353</name>
        <name evidence="1" type="ORF">BN903_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.17" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077331.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38937at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102943">
        <property type="term" value="F:trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="317" mass="33531" checksum="12C616026A7E4E2E" modified="2014-02-19" version="1">METRRALLVDAFAAEPLAGNAAGVLLDAEGLSDDQMAAVAAELGASETAFRTDEDETTEGGEAVNTVDGGEPVDDRLRYFSPTTEVDLCGHATIATYGALFAEEAIDGGERTLRTNVGDLTVAVDDDGTVWMRQQAPSVEVVDVDLGRVADALGIDPAALRDVGADLPVAVASTGLPFLVVPVNFLERLGEADPDDEAIERLSEEFDVAGVYAFTFDTLEGDSTLHGRAFVPSLGISEDPVTGTASGAVGGYLRHVDAFDGDEPDELRFEQGHFLNRPGYVRVRIESDGVRVGGQTTVSLDGEIRIPDDEDDEIIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB7</accession>
    <name>V6DUB7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_14139</name>
        <name evidence="7" type="ORF">BN903_150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077300.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54799at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="348" mass="35436" checksum="916E9816214E30C5" modified="2014-02-19" version="1">MRNPLSSTRVMEGLFESDYVRSLVVGTVGAFALVGILGLLFPDSIAGDLAGIVFSTSTATSTARLAAPIVLAGLGGIFAEKSGVINIGLEGLLIISAFVSVYAASVVGIGNAVLGVPALAIGFIAGIAASTLLSAVFAVVCIEFKADQIIAGLAVWLIALGLAPFMSTVFFGGVNTPNLGANVGWAYSATLVLIATAGSWWLLNRTAFGKHLRAAGENPKALDTVGVSVSKVRYAGVLLSGVLSGVGGSALALSIGQFVGSGETMVQGKGFIAIVAYLFGNYNPVGTLGAGALFAGLDAMQIRLQQLGYAVPDTLVQTIPYVVVIVVLALVGRTQIPEAAGEHYETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB8</accession>
    <name>V6DUB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="4951" checksum="C4A05D12E87C0606" modified="2014-02-19" version="1">MSVIDLVTGLWLGVGPDPWTVVGLSLAGALCRAIDRRDTRSVGRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUB9</accession>
    <name>V6DUB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="242" mass="26801" checksum="85D14F513D44A330" modified="2014-02-19" version="1">MGRGAVGVGDAVGPARPEIVFRPERLHVRGDGVEPRLLFQHPQHAVEQRDLRPAVVVRPVPEGDEPEAVQKRRDVPDHPVDQIGPPGRRQPLRGEVAVPVVHLAEAAAGHDVRVREGDDRRPRGVGGVEGPRQRPPQRGHVVLHRPRRGEVGRGPDRLGQPEVVLDERRQIEVPLAPFRQVPFEEQVRVDARFGVDEPLVVLEEVPPLDGPKEFAGDLRKMTVVEETGTHLQHVVKGSLSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC0</accession>
    <name>V6DUC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_88</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4359" checksum="2BBF807EE8E74AE2" modified="2014-02-19" version="1">MSMPKNADYVILLNFNVREEHVLRRTELAATRDDPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DUC1</accession>
    <name>V6DUC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C449_02537</name>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="160" mass="17773" checksum="D377D3F6AF2B3E8D" modified="2014-02-19" version="1">MSLEHSHAPDFTLESTSGETVTLSETLADGPTVVLINRGHWCSFCAEQLQTFSEVSYDLWFNDGVDVLPVVTDPIGPLTEMRDRYDLDIQLLADPDGEVADQYSGTEETERGVTGIAATYVVDGDGDVRYEQVADNPGDRTYGNYVRYFVRQEFSDPFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYC1</accession>
    <name>V6DYC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_61</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="4945" checksum="688CA887840DFF4E" modified="2014-02-19" version="1">MTGGDTPPADNASKERPPTRRTSRSAGGTTDRLTNAIDNQPSWGSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYC3</accession>
    <name>V6DYC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_59</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="43" mass="4986" checksum="8F7084E0C7093ECA" modified="2014-02-19" version="1">MTNHLGEISTEDEGRPTLARLDYHRNPQNQTRICESNIIESVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYC6</accession>
    <name>V6DYC6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2061 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_01818</name>
        <name evidence="3" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078257.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="121527at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018638">
        <property type="entry name" value="DUF2061_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09834">
        <property type="entry name" value="DUF2061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2061" evidence="2">
        <location>
            <begin position="18"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="79" mass="8602" checksum="D625FDD5D9E2A92C" modified="2014-02-19" version="1">MNLGVFSRDAVNARRRAVVKTLCYRALMVTITVVVAWLVVGDVGQAASIGLVTNAVKTLTYYGYERLWDHVSWGVGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYC7</accession>
    <name>V6DYC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OE_7206F</name>
        <name evidence="2" type="ORF">BN903_66</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="229" mass="26005" checksum="3926CF23203DC383" modified="2014-02-19" version="1">MTDTQARALETLRDIDIRLHRLFEAVDEADETTATPADPLTTLRRARSQIDAALFEHQRRTDDRTLPDNGSCVLQWDPPCTPPRRLILDPDNDSNTWTRRELEWTGESWRICGRDSVTDVAISAPAEPQYPNPIDPPTIETQLEWIRETWTHPDPDVLVFDPTATIEQGVLGAVDGELRYREADSPQWVTVTDEAALSHHLQEQGQPTVQPLSETSLTRQHFTPSPLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYC8</accession>
    <name>V6DYC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C436_21805</name>
        <name evidence="2" type="ORF">BN903_64</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="92" mass="10396" checksum="2A5749742AB942F1" modified="2014-02-19" version="1">MRYRYEQRDSKLDHLIDNLGVSSTTLEVVERFETASERSLPAGVAGVELTDSLLPHFQSVGHHPDRSDEESAVQKEVLGERDAVEETERNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYD0</accession>
    <name>V6DYD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C474_13864</name>
        <name evidence="1" type="ORF">BN903_71</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="169" mass="18789" checksum="F532850CEA77BBCF" modified="2014-02-19" version="1">MSNGSDPDAVLTALNRAQDAFEMVGRGRAAFEDGISADEDWKTQLTKACRLLEVVDTLQSQDGYYTAVIEVCFGAIERSIEAYTLAMTNDTLQDFQDHQFSYERAHQIGLFERETAEAMKDLYSENRTESYYGGGRPTEEQAEAMTDLASAVHQFAVSQIREGGVCLCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYD1</accession>
    <name>V6DYD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C436_21775</name>
        <name evidence="1" type="ORF">BN903_69</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="61" mass="6600" checksum="DB194882B5FC988D" modified="2014-02-19" version="1">MYLAQAITRCESPVVRAHLEAAREQCRNLPPTPLVECPVCGATGLPERIAVHDCPAVARDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYD2</accession>
    <name>V6DYD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_16464</name>
        <name evidence="3" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004045866.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38950185"/>
    <dbReference type="GeneID" id="55596195"/>
    <dbReference type="GeneID" id="65212881"/>
    <dbReference type="OrthoDB" id="122478at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="64" mass="7119" checksum="830707C8B1ECA1D8" modified="2014-02-19" version="1">MATGKVDFFNDTGGYGFIETDDADEDVFFHMEDVGGPDLEEGQEVEFEIEEADKGPRATNLTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYD4</accession>
    <name>V6DYD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C437_07862</name>
        <name evidence="2" type="ORF">BN903_74</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077790.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="109264at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="133" mass="15336" checksum="826A26E82D155731" modified="2014-02-19" version="1">MTEDDPFADLGETLEDEPDDEPQDTDEASEPERTEDTSTQDSVEPRDPITDTAFSYEAAKQRPFYARETTIEDFDSWLKYELEREINQQGYQNIVVREMTDALLRTVVEEDLVDEVAERFGQARESASLESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYD6</accession>
    <name>V6DYD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C472_15554</name>
        <name evidence="3" type="ORF">BN903_76</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077791.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000013.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26597at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="433" mass="48715" checksum="CCCFAC8E7098C59F" modified="2014-02-19" version="1">MTGRRSVETPIEDTFRKYLTDKGKGDAGEDGAYRTDAERELHRFRRWCLGKTSDSANATPPESWAGVVDGDTVRFVNLDTTVFSDYARYLSTAGYAAGTVLTYYAHVASWCGWAHAQGYLPRHYARESDAEDPLPENNGRRPGDQQAWEPIHRDVITQFVDRRVSEAFDALGAIEVSHADRGDPESETWQAKQKARFTAYQRCREQALVYVVAYTGLRGSEFLSAPKEDREGRNGIRWRDVSFADSSVTVFRKSREWKEASLPEPVIAPLKRYAEVLEVPESWPVFTTLHRPSLANHVTEGLADTGLDDDAIERVRAGAPDLIVAAEHDLNAPKPLTTDGARSIMERLWTHDALVERRDELDLSLDGDYLELHGGRRGVGEVLVRQFGYAAAARYLDNSEEQVREAYQHIEAAERADMATEAFSQTDQRVSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYD8</accession>
    <name>V6DYD8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Type 2 DNA topoisomerase 6 subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Type II DNA topoisomerase VI subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">top6A</name>
        <name evidence="10" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Relaxes both positive and negative superturns and exhibits a strong decatenase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Heterotetramer of two Top6A and two Top6B chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TOP6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078264.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="22842at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00132">
        <property type="entry name" value="Top6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004085">
        <property type="entry name" value="TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="PTHR10848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01552">
        <property type="entry name" value="TPISMRASE6A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="SSF56726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TP6A_N" evidence="9">
        <location>
            <begin position="67"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="361" mass="40957" checksum="D345B15A44029A7B" modified="2014-02-19" version="1">MTTESDARDELIDLAADFYDQFADGKIPEMTLPTRTKSNIEYDEESGVWTYGDRTSTRSANSVRGARKLLKAAYTIEFLADQLDDDRSSTLRELYYLSESWDNDEAQFSSQDESNDLVEDLEIVTGVTREDFHMRPEESGAKVMGPLELREQTNRGDREIHCQLDVGQGGYQIPNNPDTIEFLDNDAEFVLCVETGGMRDRLVENGFDEEHDALVVHLGGQPARATRRLTKRFRDELDLPVVVFTDGDPWSYRIYGSVAYGSIKSAHLSKYLATPEARFIGIQPEDIVEYDLPSDPLADSDINALESELEDPRFQTDYWKEQIELQLDIGKKSEQQSLASRGLDFVTDTYLPERLGEMGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYE0</accession>
    <name>V6DYE0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">C468_01915</name>
        <name evidence="4" type="ORF">BN903_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052334955.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="105420at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="13"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="223" mass="23797" checksum="7B08FB79087E02B6" modified="2014-02-19" version="1">MTVTEHTAALNDGEFVRIEYTARTAAGDRVVDTTDPSVAADADLVGIEADGPMVVVLGEGHLFEPVEEAVREAGIGGSATVRVGPTEAFGERDPRKVETVPVGLVPPEKREAGRTVSVAGRDCVIELIDEETVTLDYNHSLAGVTLEYEVSVLERLPDGDRAAGLCALHGLDADVTLSERELSIFVAGTEPSPELDRRLRAFVCDAKQLLPVDAITIDQTYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYE1</accession>
    <name>V6DYE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="97" mass="10995" checksum="D7C188C67558E5C1" modified="2014-02-19" version="1">MTAADLTDSEYAHEHPDRPSPRDDNPAAAVPFRLVEHDVGDDAASEDDEDRSPDDFRDVRVHLPLRRLLLLVLPVRSELSPIFVVSDLIIDEHLLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYE4</accession>
    <name>V6DYE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
            <ecNumber evidence="7">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C477_14268</name>
        <name evidence="7" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="7"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="153"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="216"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="407" mass="45294" checksum="84D3EF78003E3448" modified="2014-02-19" version="1">MPGETGLDFLKRVREDRPDLPFILFTRTGDEAVASESIEAGVTDYIIQEAIENQAPLLARKIITYVEHHRTKREVDRRNGRLREIAAVTDQVWWVFSPTWDELGFINDGHEAIFGQPVAELRDDPTSFLERIHDDDADRVRQAMEAVSAGDPQVVQYRVAKSDGIRLWVESRCTPVTDESGTVTSLVGLTRDITDRKLYQRELTETVDQLEEFTATVSHDLRNPINVAAGNIRLAAAEGESEPLDTAFDAIERMDALIEELLTLAKEGKTVGERRPVPFEEVVARSFENVRAPETTLRVTGSVELSCDPARLTEAFENLVRNAVEHGRSDVTITAGVFPDESGLYIEDDGPGIPPEARDRAFEKGHTTRKDGSGFGLAIVERIVNAHGWDVRIADGETGGARFEVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYE6</accession>
    <name>V6DYE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02002</name>
        <name evidence="2" type="ORF">BN903_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077810.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128933at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="114" mass="11664" checksum="E7EDC616A5443FFB" modified="2014-02-19" version="1">MVLGAIVSFVVALLVGGLGIYVSGRVVADVDDYSHAVVTALIGAVAWAIGSLIPIVGSLVALVAWVWVIKWRYPGGWVKAAIMGVVAWAAALAVIFVLNDVLNLGITALGVPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYE7</accession>
    <name>V6DYE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_16204</name>
        <name evidence="2" type="ORF">BN903_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077808.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="90282at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="151" mass="16399" checksum="2B2EC74960D7C100" modified="2014-02-19" version="1">MGQRTTEVDSDKNRAADMNIDPTLSEESKRQRDGTDNIGAFGKRTGSSDLRFFEGILPKVDGQILGDHSIEEQFSTALDNLESALADNRNATFGDVMKLEIQLTDPSAAEAIDHVYESRFDDVELPPRTVVGVCSLPGGADVQLDVIAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYE9</accession>
    <name>V6DYE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="73" mass="7983" checksum="D5BCCEEEB677A62C" modified="2014-02-19" version="1">MTARPPRTWIVKLSHGSEYPCSCILASPCGDRSPAPGRRGPVPGRRAAIEHVNYYHVKPPDPTTRSPVADSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYF1</accession>
    <name>V6DYF1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 4" type="primary">ndk</name>
        <name evidence="4" type="ORF">BN903_15</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077815.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="106462at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="3">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="159" mass="17918" checksum="C21FC2F47D07C22C" modified="2014-02-19" version="1">MSHHDERTFVMVKPDGVQRGLIGEIVSRFEDRGLKLVGGKFIRIDEELAHEHYGEHEGKPFFDGLVEFITSGPVFAMVWEGADATRQVRAMVGETDPAESAPGTIRGDFGLDLGHNVIHASDHEDEGANEREIDLFFDEEELVDYDLDTSAWVYEDEDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYF4</accession>
    <name>V6DYF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="72" mass="8091" checksum="19A24B202701836A" modified="2014-02-19" version="1">MKTPWVGGIIPGNILFQPRITRPDGDESGKQPSQSTPCVQAKRGPKHRGQRTDLRFVPFQTGRFRLYLSPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYF5</accession>
    <name>V6DYF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4519" checksum="E7F5786FB28EC63F" modified="2014-02-19" version="1">MENLEDIVLDENEEALAPAVVIATVALLAVFVVGILVSVVGLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYF6</accession>
    <name>V6DYF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_20</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="19630" checksum="F522E24798E79CD4" modified="2014-02-19" version="1">MPELRRVHVVALADVGQGRGVDADRDVVDVREVRVLDAEAHERVPGGLAERVERRPPDQHPVVVEDDGVVHASLCVADGQKGFTPRGIGRPSAGRSDPHRPNSRTNSPASSATVPAITPTNGIGTGSGITISATPSAISAVESFTADHRPRRGNTFREIPTVGRRVRADATTPALSIPGPSKTQNGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYF9</accession>
    <name>V6DYF9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L7Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ribosomal protein L8e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">rpl7ae</name>
        <name evidence="10" type="ORF">BN903_18</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit. Probably part of the RNase P complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006628114.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114541at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00326">
        <property type="entry name" value="Ribosomal_L7Ae_Arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_L7Ae/L30e/S12e/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_L7Ae/L8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022481">
        <property type="entry name" value="Ribosomal_L7Ae_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000948">
        <property type="entry name" value="Ribosomal_L7Ae_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00884">
        <property type="entry name" value="RIBOSOMALHS6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03677">
        <property type="entry name" value="eL8_ribo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Ribosomal_L7Ae" evidence="9">
        <location>
            <begin position="18"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="120" mass="12593" checksum="9F5C0A5BDC743CFA" modified="2014-02-19" version="1">MPVYVDYDTPADLAERSLEALEVARDTGTVKKGTNETTKAVERGNADLVIVAEDVSPEEIVMHLPELAEEKGIPVVFVDTQDEVGQAAGLEVGSAAAAVVDAGDAADDVEDIGEKVAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYG0</accession>
    <name>V6DYG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="16605" checksum="B1DA8081D5743FFE" modified="2014-02-19" version="1">MCRSHTCNVLDSDMCFLATDLDPSPDRFTPSSVSRRPGSLSPEHEYEDQDRQQHHDRRERALVVDNGVDRSRKHTTPIRPPRQYTSVSVTNGFRRHRDSDEWHAAARTTEDWSDFSRTARTARNDLRLRTVPWVCVTLTRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYG2</accession>
    <name>V6DYG2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_02112</name>
        <name evidence="1" type="ORF">BN903_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077826.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="69256at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="218" mass="22769" checksum="02336C2EC6200E19" modified="2014-02-19" version="1">MNLDQFTAENAPTDSAEPFQRENSYTLDVAVTGTVMAKAGSMVAYTGDVSFTGKASAEGGITGFLKEAATGEGTPIMAVEGDGHVYFADDGKKVQVIELGADESITVNGEDVLAFEESLSYEINTIDSLAGALAGGFSNVYLEGPGYVALTTHGDPIVLEPPVATDPGATVAWGGTSPDVEVNRSLSDMVGQESGERYQMRFDGDGGFVVIQPREEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYG4</accession>
    <name>V6DYG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5203" checksum="5295DADA291338AD" modified="2014-02-19" version="1">MAAQRRPTTDGAVTLADLFHLFRQPPALATAAEREALNPRRRWVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYG6</accession>
    <name>V6DYG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C467_07335</name>
        <name evidence="5" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077823.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="80199at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="68"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK40413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="247" mass="26942" checksum="70ADD9A1B14FBBEA" modified="2014-02-19" version="1">MDRRHFLRSLAGTGVVAGTTATAGCAGVLGDTDGSSNGDEGSDSPDGSGDEETILGPPEQSRGDPVHPIRGDEMPDFTVPDPITGEEISTSQFEGERAYLWTSFYTSCPDGVCPALILRLRRAQEVAAEEGFGDEAAFLAQTFDPERDTADVLREYAGQRGVDLDAGNWHFLRPESYEAGVELMDENFGLKIQKTDGEQYESLEYAFPHYGLILLVNKQGIVERAYPRGPATDIERIVDDFRRVVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYG7</accession>
    <name>V6DYG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_30</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="3881" checksum="39B33FA21F9D68FA" modified="2014-02-19" version="1">MSASRIGSAGAASVELISVGTRLAVIMVLDSTHNTVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYG9</accession>
    <name>V6DYG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sensory box protein</fullName>
            <ecNumber evidence="6">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C472_10914</name>
        <name evidence="6" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="6"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078290.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000022.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16486at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="15"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="141"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="278"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="482" mass="53240" checksum="F99E65381CEBA99D" modified="2014-02-19" version="1">MSIEDPQEAATAPVEVLHVDDDPSVLDLTESFLDAELDGVAVTTTTEPEGVIDHLAAGTFHCVISDYDMPGRDGLEVLCDVRDEYPDLPFILYTGKGSEEIAAEAINAGVTGYLQKGGPDQIRRLANRVEHAAVEYRSQIESERYSTVLKALDYPIYVVNEDAEFEYVNEPFVDLTGYDREEIIGSSPGLIKTESDVKKANEKLAEIVSSTGPERRKFSVDIRSKDGKEIPCYDHMAALPFDEEFRGSVGILRDASEEQRRREELLRQNERLEEFTSVVSHDLRTPLNNAEAAAELARLDGDEEHFDRLASEHERMEQMIRDLLRLARNGRTVSETEPVDVGAVASEAWKSFGCPTDELELPDGELVVEGDSARVRQLIENLLRNAVDHGQSPVRVRVREHAGGFHVEDDGPGIDEDRVDEVFEPGFTTASDGTGFGLTIVKRIADAHGWAVDVTESDAGGARFEFAVDAKANASLEEPHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYH1</accession>
    <name>V6DYH1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translation initiation factor 1A</fullName>
            <shortName evidence="3">aIF-1A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">eif1a</name>
        <name evidence="6" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006628131.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="34508521"/>
    <dbReference type="GeneID" id="55595502"/>
    <dbReference type="OrthoDB" id="102432at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="PTHR21668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="5">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="11023" checksum="F4BBA3A294E16677" modified="2014-02-19" version="1">MSEESGRKNLRMPNDDEVFAVVTEHLGGNHVQLRCADGVERLGRIPGRMKYRTWISEGDVVLAEPWDWQDEKANVEWRYEDEDADQLRREGHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYH7</accession>
    <name>V6DYH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02162</name>
        <name evidence="2" type="ORF">BN903_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077835.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95484at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="244" mass="25241" checksum="73221DB61DC814D3" modified="2014-02-19" version="1">MSDDPPAAAVGERLTRVASALFAIVFAFLVANAVTVPGTNFAASLGLVSEGSNGYRLLQTLLQFAGFVAAIAGYLAVTDQWDLARASRPTAREAGIIVGGGVLLFGFQYGALFALDQIGLSTGQNQAVVPGGDPVTYYLAMIAVSLAVVGPVEELLFRGVVQGGIRRAFDAAPAILIASVAFGLIHLPAVSGTMVEQWAYVGVVVVLGAVLGAFYEWTDNVVVPGLVHGVYNAVTYVVLLAQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYH9</accession>
    <name>V6DYH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_06182</name>
        <name evidence="2" type="ORF">BN903_40</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005240">
        <property type="entry name" value="DUF389"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20992">
        <property type="entry name" value="PTHR20992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04087">
        <property type="entry name" value="DUF389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="430" mass="45015" checksum="BF1B3E6025DB838E" modified="2014-02-19" version="1">MRLVQVMIPAGKRAAVVRALDDEGVDYVVTDETSGREYTAVATFPLPTAAVEPVLERLREAGIDESTYTVIVAAETVISRRFEALEEQYEEDAEHGGDRISREELQAKAEGLASGLGTYVLMTVISAVIATAGLLLDSPATVVGSMVIAPLIGPAMSAAIGTVVDDESLFRRGVRMQILGVAVAVFAATAFALALRSLALVPPGLDPLELAEVSERLAPNVLVLVVAVGAGIAGIVSLITGVSATLVGVMIAVALIPPAAAVGIGIAFRIPRLVIGAGIIVAVNVLSINLSALVMLWYEGYRPQRWFREDDARAAFLKRVAVLAVAIALLSVFLGGVTYDSYVASTTETDIRAAASDELTALNSEFELLELTVERTGTVPPLKTDRVVVTVGVPPGGPVEGIAPVLDGRIETVVDGEVTVEVRTVTVERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYI1</accession>
    <name>V6DYI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_38</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="41" mass="3862" checksum="899315BA862608D1" modified="2014-02-19" version="1">MAESYAAADGGDASGGASTAVETGDVSVSVSVNVVYEAVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYI3</accession>
    <name>V6DYI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_27</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="38" mass="4181" checksum="94A7FF82BCE33A4B" modified="2014-02-19" version="1">MTGLITSIPSERAVPTYKPAGRTAGRLRRRGFLNISHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYI5</accession>
    <name>V6DYI5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydrofolate reductase</fullName>
            <ecNumber evidence="1">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">C467_07195</name>
        <name evidence="6" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="5">
        <location>
            <begin position="10"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="178" mass="19355" checksum="57ED7B2E89C3C40E" modified="2014-02-19" version="1">MMAGDDADPDLVLVAAVAENGVIGDDDGMPWHYPADLAHFKRLTTAHPVIVGRKTYEGIRDRLGGPLPDRTSVVMTTRSIDDGDLSDGAVVAHDLDEAVSRATADAADRGVDAVYVIGGATVYEQFLDRADQLVITEIPERPGGDARFPEWDAEEWAETDRERADDLAFVTYERRGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYI7</accession>
    <name>V6DYI7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Imidazole glycerol-phosphate synthase</fullName>
            <ecNumber evidence="3">4.3.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisF</name>
        <name evidence="6" type="ORF">BN903_32</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">AJ67</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000022">
        <property type="protein sequence ID" value="CDK40936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CDK40936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="215" mass="23103" checksum="103D04C7D6829CC0" modified="2014-02-19" version="1">MGLTKRIIPCIDVDLDEEGDAAVYTGVNFENLEYTGDPVELAKKYNAAGADEFVFLDITASAEGRETMLDVVNAVADECFIPLTVGGGIRTKADIKETLRAGADKVSITTGALERPELIEEGAAAFGSQCIVISVDARRRYDDGGEHFYEDEDGETVWFECTKKGGREGTGIDAVSWAQEAEERGAGELFVNSIDKDGTKDGYDVPLMKAVGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYI8</accession>
    <name>V6DYI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_43</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="52" mass="5972" checksum="41B1AFBC6B728DD4" modified="2014-02-19" version="1">MDDVRKLRPAFSRAFPSLSSRVPPTSATDRVAVSVPVRSRFFFCPRRHSPPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYJ3</accession>
    <name>V6DYJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_02267</name>
        <name evidence="2" type="ORF">BN903_48</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006628157.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="GeneID" id="38950889"/>
    <dbReference type="OrthoDB" id="111320at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043835">
        <property type="entry name" value="DUF5811"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19128">
        <property type="entry name" value="DUF5811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="125" mass="12444" checksum="623B78ABDE1D69BF" modified="2014-02-19" version="1">MNGNNPYAGAPGVTDAGSPAAVDLSPDQERQLRRAVAGIVSRTESYLPDSYAVGSELSVGANGPQATVAVNPPAGHPVSAGFTPDPEDLDAGIAESDTDEVARGLAASAAVQVMDAVGDITPTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYJ5</accession>
    <name>V6DYJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nicotinate-nucleotide pyrophosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C467_07110</name>
        <name evidence="3" type="ORF">BN903_55</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_C" evidence="2">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="88" mass="8735" checksum="899A3132C989B11C" modified="2014-02-19" version="1">MEDPTDAARAAAAGADVVLLDNMTPAETREAVDRVAAGDADALTEASGGITVETVPDYAATGVDVISMGGLTHSAPTLDLSFRTGGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYJ7</accession>
    <name>V6DYJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="44" mass="4804" checksum="E47BF67CEE43C22B" modified="2014-02-19" version="1">MGLEGAVARTKTRDVRTAGASNASDEDRSERIESSRLGLRRSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYJ8</accession>
    <name>V6DYJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="113" mass="11133" checksum="4ED449251C87FB5C" modified="2014-02-19" version="1">MCPATEVSRYSAESLADEESDGPADDGSDGSADGDSDAESSDDGDEPRVYEETEGTPTVSRGGAPAADAADTDDGGGVAMISVSKLLCGSTPRATGSATTRADGSKETADHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYK1</accession>
    <name>V6DYK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetamidase/Formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_02327</name>
        <name evidence="1" type="ORF">BN903_60</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077852.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000014.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17853at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="PTHR31891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="435" mass="46023" checksum="880DCD576E200BA6" modified="2014-02-19" version="1">MSQKEVRDELYVDQYTLGLVGPDQEWAGTVADGGTVKTYTPPGCWGPMVTPSFRGGHEVTRPIRVEGAEVGDAVAIHVRDVEVTSMATSTGSMAEREGAFGDDPFVDHRCPECGTAWPDSVVEGTGEDAIRCAECGANASSFGFEYGYTVAFDHENAVGITLDEEGAHELALDADEVMDIPENARQHPILLYEPDEIPGTLGRLRPFIGNIGTTPPVTMPDSHNAGDFGQNLIGADHDYGVETEEDLELRTDGHMDVPEVRAGATLICPVVVDGGGIYVGDLHANQGDGELSLHTTDVSGTVTMDVEVIEDVELGGPVLLPNEEDLPFISAPYTDEEVAAGEGLGAEHGVDVDTDAAPIQVIGSGATVNDATQNAFDRAGKLLDMTEGEVRARCTFTGGVQIGRLPGVVQLDMLVPMDILADAGLDAAAREQYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYK2</accession>
    <name>V6DYK2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C448_06720</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000014">
        <property type="protein sequence ID" value="CDK40448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12217" checksum="4E95316EE0A614EC" modified="2014-02-19" version="1">MHSYYERVDADDYDGLLALFADDIVYDRPGQDSIEGIDALERFYREDRPLSDGEHEVLVVAVDGDTAAVRGTFGGRQGGERVAFGFADFHTVDADGLIAHRVTYTDRDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYK5</accession>
    <name>V6DYK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000023">
        <property type="protein sequence ID" value="CDK40946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="6139" checksum="03E3E80570B6D0A3" modified="2014-02-19" version="1">MRLDVLRHRLSDRPRPVLDPLVAPHPIELRDDLVGDVETCSHGLVVDAADTRTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPP4</accession>
    <name>V6DPP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="271" mass="29533" checksum="89886884F9B1EAE8" modified="2014-02-19" version="1">MLLDGWVFGSELVGASNAALWGVGCMVDESSRFTSDRRGRGEASWADEEDWNAGVSENVVVAGGGLSPHFAEGDAQYTVFDDFDDGVFDTSIWRKVIVSGGSVSERNNQIELRGGGRGDNRPYLRTADEVQDGQNGNPCSLDAMIEFAGDRQQIVIALFWDGTAVGKYATAENSIEVHYSQDAQEWRIQMREGTEFRREVQVPFNFGSGARQVEIDFNGDFSSFTIDLVVDGSSVLSHSDSFSPTASCPFVGFAPREFSGGINIDSIGFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPQ3</accession>
    <name>V6DPQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048075992.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000001.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="137" mass="15322" checksum="8A906F844E9F1B86" modified="2014-02-19" version="1">MSDDDMLNEVTVCFTNGDELNVDAVVRLVGAEWLTAEIVQPSDDGEDGSMDFEYVALRADDVRYIRSDRVTPAGQNGTNFRVHHTHGYEGEEPDIMFEAWIGQHQLHPDDDPSAYQGSEQKWPPDGADPRYPGEAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DPQ7</accession>
    <name>V6DPQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000001">
        <property type="protein sequence ID" value="CDK38141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4298" checksum="E6486E272A83D2E8" modified="2014-02-19" version="1">MVLWGILCGWAGSLGDPCPVFRIDEVRVAVRVDIRVVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ13</accession>
    <name>V6DQ13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na+/Ca2+-antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_12271</name>
        <name evidence="7" type="ORF">BN903_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076195.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43312at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="13"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="191"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK38327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="342" mass="35539" checksum="EE40C7543D767DF1" modified="2014-02-19" version="1">MTGLLPDAPVVHVLVIVAATGFIWLGSGWLEEAAETLSGYYGLPAVVQGSVVVAVGSSFPELVSVLVTALTGVFDMGVGALVGSAIFNVLVIPAVAGIGGEGELEANRTIVYKEAQFYMLAVSALVVTFALAVIYFPVSSDPIVGTMPRSLAVIPLALYALYLFIQYQDVGDAAIDNVRDGVDVRREWAKLAAGLGLIVVTVERLVASVESLGVTFGIPEFLAGVTIVAAATSLPDTLVSLRTARENRGATSLGNVLGSNTFDLLVAIPLGVLIVGEVAVNFSTAVPMLGVLTVATVLLFVTLRTELALERRESYALLAAYGLFVAWVVAETVGATNALRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ18</accession>
    <name>V6DQ18_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_08651</name>
        <name evidence="2" type="ORF">BN903_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076199.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="108947at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="116" mass="13126" checksum="8AB9767EADACE81A" modified="2014-02-19" version="1">MRAVRFDEAETYEPDAGWRRVAMAGSDRFSFEWFEKPPGHSSPLHDHENEQVCLCLEGELTVVTDDGDEATLGSNDSVHLEANEPHRVENTGDERAVGLDVFAPGRSFDFWTDREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ20</accession>
    <name>V6DQ20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="48" mass="5343" checksum="12ABD395B6489C8A" modified="2014-02-19" version="1">MSDYEGDPDQEDDSAFRTLEEQRGHVDSDENGRRQVFLGSAGAARRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ23</accession>
    <name>V6DQ23_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0212 protein BN903_12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_00462</name>
        <name evidence="2" type="ORF">BN903_12</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0212 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076203.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103672at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01223">
        <property type="entry name" value="UPF0212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007564">
        <property type="entry name" value="UPF0212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42199">
        <property type="entry name" value="PTHR42199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04475">
        <property type="entry name" value="DUF555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016934">
        <property type="entry name" value="UCP016934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="126" mass="13770" checksum="A1CEBDC4DBACC9F0" modified="2014-02-19" version="1">MDCRVVVEAAVPVYDVETVDEAVRIAISKTGEMLNPDLNYVEIDAGTRTSPSGEQLDPAFVAADEALVALELQMDVFNVDRDEHASRVARKEIGKRLRNIPLKVLSVTEIDPEESDRAADDESAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ27</accession>
    <name>V6DQ27_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIB</fullName>
            <shortName evidence="7">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">tfb</name>
        <name evidence="11" type="ORF">BN903_9</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076201.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="35979at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="10">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="1" evidence="7">
        <location>
            <begin position="178"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="7">
        <location>
            <begin position="272"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDK38334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="360" mass="39546" checksum="613620F88F8AFFAB" modified="2014-02-19" version="1">MTETDTYSGGGTERERLTNANDATDTNGGDESGERTRTRATESATERSESAEETTSEREGERTTTCPECGGRLASDTEHGETVCSDCGLVVEEDSVDRGPEWRAFNSGERDSKSRVGAPTTNMMHDKGLSTNIGWQDKDAYGKSLSGRQRRRMQRLRTWNERFRTRDSKERNLKQALGEIDRMASALGLPDNVRETASVIYRRALSENLLPGRSIEGVATAALYAAARQVGNPRSLDEFTAVSRVEKMELTRTYRYVVRELGLRVQPADPTSYVPRFVSRLDLSDETERRARELLDDAANAGITSGKSPVGLAAAAVYAAALLSNEKVTQSQVSDVADVSEVTIRNRYKELLEASGDVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DQ28</accession>
    <name>V6DQ28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C467_00437</name>
        <name evidence="1" type="ORF">BN903_17</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048076208.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000002.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="110560at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="94" mass="10202" checksum="DEA73C9AD9D9F2A0" modified="2014-02-19" version="1">MCADTFGVGIRVTETELRVVVGVPSDIDSGWTDPETFQSLVAETVWERLDQRRTLEAVAARYETGETAPLGSVTIEPDGTVMETDLERVGAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX0</accession>
    <name>V6DTX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="8968" checksum="A15A86CF083289A7" modified="2014-02-19" version="1">MSWISVIGTSVRAYKYPSTRCSLPRRSGVFRPVVPTSSSLSPGARFVPLSTVHTAAPLADSGGSTPARNRVLYRRSSAPLHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX1</accession>
    <name>V6DTX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_53</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077231.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12146" checksum="22FC77FCBFCC28A2" modified="2014-02-19" version="1">MSDDQVECDYCGQEYDKRGIGAHEAHCDEATEEEMQPDSGASDLSTFEAEVRARDDGQCARCESIEALVVHDVDPDVEQERANAVTLCEQCEDELTGLHPLTKRTKIGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX2</accession>
    <name>V6DTX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_21</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="39" mass="4192" checksum="8BC4744FB2D6D0E8" modified="2014-02-19" version="1">MSQIAPGPLLTNAFSASTSESADQEVRTRGSIEDRPHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX4</accession>
    <name>V6DTX4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C481_11100</name>
        <name evidence="2" type="ORF">BN903_58</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="506" mass="55578" checksum="A4EA9C6119EF7662" modified="2014-02-19" version="1">MSLSDRIRSRTNQAREALLSTADPQTKQSSGDYSGFTVRGETNSISPDSGDIEAYWEQYRSNPLVRRGINIYASDVVAPGYRVEAIDDDLVDELLEWLSGAAIVAGESNQDFVEILEGSVVHEEVRGSCIVEKIPTKENPEETWGFRLVNPSTVEAYTYDSQAVLIRPDDTDVSGVQLTPRGEAAAYGQWGNGALAGPFNKDTVYLSQDDIIKMVHDPDTADIFGNSTIEPISKEIAELDRMLSDVGEAVHSKGYPHWVFKLGEPNGDAQNPRAGIWPEEEMTSYRDKHKAGEWDVEDKDFVPGDVEIDTISSDVPEIEELLDWLVEEIISALPVPKYKLAHTDSINRDVTSEQTPQYERRVEAKRHKLESIFTPVLKEKAAQLGYSDEAVSSVQLTIEEPTEENPLRRDGFDADEFATLAQGLKAATGEGESPRDIVPAEEMRGILGLPDVDEAEESALESGLDESDANVQAEFEELYGEPATPDSVGDGGDVELDTSSGEEDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX5</accession>
    <name>V6DTX5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA double-strand break repair protein Mre11</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C472_08429</name>
        <name evidence="2" type="synonym">mre11</name>
        <name evidence="5" type="ORF">BN903_148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="2">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">Nuclease activity is regulated by Rad50.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077192.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000006.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25870at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045027">
        <property type="term" value="F:DNA end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02044">
        <property type="entry name" value="Mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032885">
        <property type="entry name" value="Mre11_archaea-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="4">
        <location>
            <begin position="3"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="443" mass="48418" checksum="9AA0A54AE4CD9B77" modified="2014-02-19" version="1">MTRVIHTGDTHIGYSQYHSPVRRQDFLDAFEAVVDDAVDDGVDAVVHAGDLFHDRRPELRDLMGTISVLRRLDDAGIPFLAVVGNHESTRGGQWLDLFERLGLATRLGDEPVVVGDTAFYGLDHVPVSRRDDLEYAFADHDAEYAALVAHGLFEPFGYADWDTETVLTESDVAFDAMLLGDNHTPDTAEVADTWVTYPGSTERASASEREGRGYNLVTFDADAAGGDDRVEIRRRALDTRPFVFVEVELREGEGESRVRERVREYDLTDAVVHVEITGEGEPVTPAAVEEFATEEGALVPRVADRRDVETDGEVDVSFADPEDAVRERLDEMSLSTVARDVESAVRSDTVPDANVRGTVKRRVEERLDEEEELGAFDPAGSDSEPVDSEAETVGSDAETGDSDDGDTDDSDNNGEPEAGSDPEEPADDGAASTDGQVSMEDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX6</accession>
    <name>V6DTX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_26</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="47" mass="5361" checksum="7A8F64B3658D2EC5" modified="2014-02-19" version="1">MIFEQSKRSINEIVPTHGRWRTTDRVGADVRDDENGISLGVDCNRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX7</accession>
    <name>V6DTX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C467_12606</name>
        <name evidence="7" type="ORF">BN903_294</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="258" mass="26762" checksum="41642BF5A887F3F9" modified="2014-02-19" version="1">MLSPFGSGDRARFQRAAAVNVVGNAVKIAVVGATGLAFGSVALLADAAHSVADLVASAVVFVWGGSRYEGADETHPHGHQRIEPLTALFVGATVAILGLLLLRESVLGFVGPVEVRPSPLLVGALLFAMADMYLLYRYTELVNADLGSTALDALAVDSLNDIYTTVAALVGVFGVLLNVPVLDPVAGALVSALVVYQGIEIGRENVTYLVGAAPPPGDRNRVVAALRDHAAVRGSTTSPCSTTGRTWRSRSTSRSTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTX8</accession>
    <name>V6DTX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Succinylglutamate desuccinylase/aspartoacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_01818</name>
        <name evidence="1" type="ORF">BN903_348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000002">
        <property type="protein sequence ID" value="CDK38673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK38673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="55" mass="5693" checksum="58444CB04F9C2459" modified="2014-02-19" version="1">MVAATGAERGEVTADRDGYVLGRTEGVAAYEGDPIGSLAVRDDSELVVPREAGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY0</accession>
    <name>V6DTY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_05452</name>
        <name evidence="2" type="ORF">BN903_153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000006">
        <property type="protein sequence ID" value="CDK39601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="240" mass="26152" checksum="EE146A0228DA7CC6" modified="2014-02-19" version="1">MLPDADAVVFAASSGGRGADAAREVYVDGLANVVDEYGSRASPPDRLVYTSSTGVYGDHDGGWVDEETPVEPTTEKTRVLAEAERIAAERAADAGIDGTVVRFAGLYGPDRYRLERYVEGPVTAGHLNMVHRDDAAGSIRHLLETDSARDRVVLVVDDEPVDKHAFADWLADACGVARPEKRSKDERIAAGDLSAAAERRIRTSKRCSNALLRDLGYEFVHPTFRSGYREAVRAYRVATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY1</accession>
    <name>V6DTY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_31</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077222.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="74" mass="8210" checksum="3440E8FD5C955A36" modified="2014-02-19" version="1">MLDGEKELDDFIRKENAILHRNQGDILRGLVDEMVTTQAVRVALKEDGLDPDRIDGIVATIEEVENTVSGDADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY3</accession>
    <name>V6DTY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK39005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="56" mass="5545" checksum="61FC9A99486308CD" modified="2014-02-19" version="1">MFSSAHSVASPYGTTHKKPRGTAAGRPSSPGTAKSNDDAVACAVEPAARVQSCGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY4</accession>
    <name>V6DTY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11055</name>
        <name evidence="1" type="ORF">BN903_68</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077242.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="136057at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="110" mass="12148" checksum="B1C7292C7198A1DD" modified="2014-02-19" version="1">MPRIVPHDVSEILETELDVGDLSAFIEDAHIVVNRRCKPFTDDESALADVETYLAAHIATAKEPRVSSTSGAVTKVTLDTDADRYWNRALLLDPTGRLNSPQRGYSVYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY5</accession>
    <name>V6DTY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C467_14489</name>
        <name evidence="2" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077213.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99870at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="142" mass="15382" checksum="EB491116AC108705" modified="2014-02-19" version="1">MLITKDEGLDRLLDAETIAVVGCSTTPGKAAHDVPAYLQEHGYHVIPVNPYADEILGERAYDAVGDVEETIDLVDVFRPSEEVPEILDAVRERHASRGDAGAAWLQLGISHDEAATNAAADGIDVVQDRCIKVEHGRLRGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY6</accession>
    <name>V6DTY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077225.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000007.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="186" mass="20948" checksum="46FEE01509EAF08E" modified="2014-02-19" version="1">MSDFFDNKIESGCKLVDQTLMLEFVEAVDKLDSHRDLLRMMVEDERQWFRLKLRNDVEENTLAELDSAGLIESRSNGGEEQPDFRATGRAQYLFDSIPEDGELDGVEVGALFVVAGDIWDIPGRQIEWAEQDLTVDVSDRGLRLLLDGGLIQLVSAGEAGSNQSDMWMSTRRLEQLQSLIYGFAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DTY8</accession>
    <name>V6DTY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C481_11040</name>
        <name evidence="1" type="ORF">BN903_73</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="46" mass="5230" checksum="098D04F2413F33E8" modified="2014-02-19" version="1">MPETIPDPKLTVRDILRDLWDNGSVYEALGDRDIHTGWFDGSVQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU91</accession>
    <name>V6DU91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="5873" checksum="C81ECC11A4EEFB28" modified="2014-02-19" version="1">MVTVTTTHITTVVNTNTHGFSKSIRRTSAIHQLPISIVNTFPELNGKYMSVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU92</accession>
    <name>V6DU92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hlac_1432</name>
        <name evidence="2" type="ORF">BN903_82</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003847">
        <property type="entry name" value="Put_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02697">
        <property type="entry name" value="VAPB_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="85" mass="9858" checksum="8C70D299029C6069" modified="2014-02-19" version="1">MLPRWQTFINIRIRLCAVMSTKTISLDEEAYERLKSHKREGESFSDIVKRIAGERSWTEVAGILSEEEADELESLVEDGRSRSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU93</accession>
    <name>V6DU93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative signal peptide protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C472_05813</name>
        <name evidence="1" type="ORF">BN903_23</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048077335.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000008.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="81547at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045396">
        <property type="entry name" value="DUF6517"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20127">
        <property type="entry name" value="DUF6517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="220" mass="23181" checksum="6BE7A49F644B9733" modified="2014-02-19" version="1">MNRRGLLAALAASTSVAVAGCAGQDQNLDLNAEPARIPESAYADGFTGQEPESFSIDREFNATGVNVEVSATTWVAQYTNDEIGSALFVASTPNESVAGQSVNPLVRVEGAELIRRLLDQIDQQGIGGNGTEIQTDDIEEAGEETQTILGEETTVSILETTVSADVNDASNQSGSVEDVPVLVYIATVQDGDDVIVTVGVHPQEIDQSEQLLSMMGSIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU94</accession>
    <name>V6DU94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl-CoA epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C470_02095</name>
        <name evidence="2" type="ORF">BN903_125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="143" mass="15394" checksum="822440895AC6D032" modified="2014-02-19" version="1">MRFDHVGVATRDATTLADLFGGLLDAPVAHEETFDGMRIVFLELDGGGYFELLEPDTGGTIADYLDREGPGRFTTSPLAVDDLPAALDDARDLRALGPPSXXXXXXXGIDLVDEEPRPGAWGHEVAFLHPRSTGGVLVEFVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU95</accession>
    <name>V6DU95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">C472_03593</name>
        <name evidence="7" type="ORF">BN903_151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK39752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="263" mass="26911" checksum="ABB71004F5B23802" modified="2014-02-19" version="1">MLIAVGTAAGAVGGGLWGAIPGALKAYADANEVITTIMLNFVAANVAYVLVLEVFRAEGSSVVATEYVPEYAQLRPWLFPASSDFALVALLIGVGFIGALYYFVEHTSLGYDLRTSGVQAAAAEYGGVNAKLTTVRAMTLSGALGGVGGAVWVLMSEGRWLASIPDLGFDGITVSILAGNNPIGVLPAAFLFGVLKGGALEIGFRTDVPTQLVAVLRGLIILFVAMPEFFRMIGRYAGLGGGGVAAPTESDETAGGEGGETDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU96</accession>
    <name>V6DU96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Hmuk_0947</name>
        <name evidence="5" type="ORF">BN903_78</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000004">
        <property type="protein sequence ID" value="CDK39095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="73"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CDK39095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="261" mass="29119" checksum="87EF7A1857241E6F" modified="2014-02-19" version="1">MVYMTENRTPRRIKSVGIAFDILKILRDEEGATVTEVSEAIDRSPGTTHTYLVTMEEKGYVRVEDGEYQVGLFALPLGEYVRATSRLYQIGKSEVDKLAQETGEAAHLVVESHGHEILLYEQFGHNAVGEDLYTQIKGYPRRNLHCSAASKAILAHIDESRRTEILNGYEFVARTPNTITDVGTLRAELERVRQNGYAINDEEQITGVRAVAAPIIHEDTIYGAISLSTPASRMQEDEFVNTAPERVLDVANVIEVNIQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU97</accession>
    <name>V6DU97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_11819</name>
        <name evidence="2" type="ORF">BN903_87</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000003">
        <property type="protein sequence ID" value="CDK38793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK38793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="180" mass="19794" checksum="C3961BDCD2BF3B32" modified="2014-02-19" version="1">MFSRDPMPTLDFETDAHVDEYVVDAENTTVFAASDGELTYMRAGETAAVSVPVGDVNGVEFDRNDGLRRHTFLGLFFLVLSLVLTVGTVLLVYQGRVESPREIGLAAFLSVFVLGGWNTAYDLLSRSDRDVIDVYVTAEADTHVLCGEVDDDEFVDACQQLVDSRVPTTNRHPALEAELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU98</accession>
    <name>V6DU98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BN903_28</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000008">
        <property type="protein sequence ID" value="CDK39789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK39789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="42" mass="4579" checksum="20ABEF3CFE437196" modified="2014-02-19" version="1">MRHSIGAVPRLACGAKTRTRGGPASDRRERVGPREEMTEGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DU99</accession>
    <name>V6DU99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000007">
        <property type="protein sequence ID" value="CDK39757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK39757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="37" mass="4195" checksum="8996E70F74B8B4B3" modified="2014-02-19" version="1">MCETSFMLSRSSATLTPDTPDLRINPSWKEIMSPHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYA1</accession>
    <name>V6DYA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase ISH18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C463_14465</name>
        <name evidence="2" type="ORF">BN903_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="121" mass="13630" checksum="CC72AABA3F7DE412" modified="2014-02-19" version="1">MYPGIDIHKRYAQVAVMDEAGTIVEEVRVENANLDDLAQRYAGAQAVLEATSNYYHIHDTLSEHLDVTVAHPKKINQIADTDKKTDRVDAKELARMLRLNSVPESYVPTEEVREARALVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYA3</accession>
    <name>V6DYA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISH9-type transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C473_00267</name>
        <name evidence="2" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="214" mass="24394" checksum="9A361EB83437F665" modified="2014-02-19" version="1">MAEVRDALDLDQDDLPDHTTIHKSFDRLKMWVWRALLRVSAQQHPQSGHVALDSTFFDRQRTSSYFRQRAGQTIQTLKATTVTDVESLAVLDVHIAARWKHDTKTGPQVVRVSADDLQSVAADNGFQDWHTEYEIAAHDVEYLVHYRGSSAKAAANNALNRANGYSQRWMAETSYSTTKRSLGDAVRALSWYRQFREIVLMFAITNIEPLCEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYA4</accession>
    <name>V6DYA4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">30S ribosomal protein S4e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">C470_10500</name>
        <name evidence="7" type="synonym">rps4e</name>
        <name evidence="10" type="ORF">BN903_39</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">AJ67</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078230.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000020.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="89943at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="KOW_RPS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_S4e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_S4e_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_S4e_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_S4e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018199">
        <property type="entry name" value="Ribosomal_S4e_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="PTHR11581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00528">
        <property type="entry name" value="RIBOSOMAL_S4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RS4NT" evidence="9">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_S4e" evidence="8">
        <location>
            <begin position="91"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDK40861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="239" mass="25843" checksum="7E7059AF86DF80FA" modified="2014-02-19" version="1">MTRHQKRLSVPNSWPVERKTDTFTVKAGAGPHGEAGVPLVVLLRDVLGYVDSTKEARYALNNDSILVNGDAISDEQRPIGMFDILAFPERGEYFRVFPDEGGRLALTPVDEEAAGSRLGKITNKTVVPGGVVQLTLHDGTNVRVDDDADYETNDSIVVDNETKEIVAHFEYEEGALVTAVAGQHAGQIGEIDDIDVTLGSGDNTVTVASEDGGYETVEEYVVVIDENFTDDEEAGDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYA6</accession>
    <name>V6DYA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_12645</name>
        <name evidence="2" type="ORF">BN903_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="185" mass="21327" checksum="1A7B3462B4F667D2" modified="2014-02-19" version="1">MIAPTLALLALLVSQRVWGGWPDLWRVRRVALPIVDRLADGDYDETVDAIDEHTSIDVSSAVDKLSEKTGLPLNTRTFVGVIDVPPSEVREEFQSIPRWWPCWLASIQYEMRDEQRVYEVGSYAFRSEGLLNPRQVHVRLTPREGTRRQHCGRTRSGRPGDGRWRTTAVRRGRRSTGCDTWRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYA8</accession>
    <name>V6DYA8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpl2p</name>
        <name evidence="4" type="synonym">rpl2</name>
        <name evidence="7" type="ORF">BN903_44</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_A">
        <property type="entry name" value="Ribosomal_L2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_L2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="89"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="275"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="290"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDK40866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="352" mass="38180" checksum="F18E74F193BC5227" modified="2014-02-19" version="1">MGRRIQGQRRGRGGPTFRAPSHRYKAELSHKKLEDVDTITGEIVGIEHDPARSAPLAEIEFEDDDRRLVLAPEGVRVGETIQVGVSAEIKPGNTLPLAEIPEGVPVCNVESNRGDGGKFARASGVSATLLTHDRDVAVVELPSGEVKRLDPQCRATIGVVAGGGRTEKPFVKAGNKHHKMKARGSKYPRVRGVAMNAVDHPSVAVVANTPDSRSPSRGTPRRDARSVTSHPSAPDEVATNEFRLPNRPRGQGVRLPRSLARRAAGDGRRRGRGTAPRTPAAKHRSRTRHRTAEAAGDGPEPRQGDDGRRPDPDASARHADPAGVRRRHLLRVQRSQLRARSGRARDDRALPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYA9</accession>
    <name>V6DYA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BN903_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="83" mass="9391" checksum="2C4B7A10818494C6" modified="2014-02-19" version="1">MVGEVDVGVLAVVPNGAGRTADQQEYLERLSRTVVPHLPVDAESRWWIVNVGVSRGTMGIKYREYDTMVLWHRITSHITERQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYB2</accession>
    <name>V6DYB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C469_10916</name>
        <name evidence="1" type="ORF">BN903_51</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="111" mass="12938" checksum="70D1D73DF4D06F93" modified="2014-02-19" version="1">MTDFDRLSERTTWIDLSFVERDRTPRWAIEVGIRCHLAGMSLREVSKFLEIFGINRTHVAVHNWVHKADLQPISTVSADQLAVDEKMIRLHGQKFWLYGAVDPYTNEIPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYB3</accession>
    <name>V6DYB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hlac_0923</name>
        <name evidence="1" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="53" mass="6174" checksum="45D84FC15496644E" modified="2014-02-19" version="1">MTRWFLTELHRRYQLDGVEFLVDDADYLGPVFAEDGGCHRTIVMGGMRERLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYB4</accession>
    <name>V6DYB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase domain protein</fullName>
            <ecNumber evidence="2">1.1.99.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">C472_06005</name>
        <name evidence="2" type="ORF">BN903_49</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.28" evidence="2"/>
    <dbReference type="EMBL" id="CBVY010000020">
        <property type="protein sequence ID" value="CDK40871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047061">
        <property type="term" value="F:glucose-fructose oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="1">
        <location>
            <begin position="14"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CDK40871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="187" mass="20458" checksum="FAF92573644F0A5D" modified="2014-02-19" version="1">MSQTMLGELGSDTDQWRLDPELSGGGALMDLGVYPLNTTRFALGSDPVRVSGRTRSEHEAFADVDEHATFRLEFPGGVDALCTVSQNAQHASRLEVTGTDARLILDPAFYEREDRGFAVVRDGTRVDVEFDQVHQIEEEFAYFGHHLLAGEPFHPDGEHALVDVRALDGIYESAETGRPVALDGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYB6</accession>
    <name>V6DYB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTR-like protein</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">C491_04200</name>
        <name evidence="3" type="ORF">BN903_56</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="178"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDK40370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="373" mass="41171" checksum="29F2F967D2205D55" modified="2014-02-19" version="1">MMGRTNNGDIRYEQVVSKLHDVASELAKRDSREEICQQIIDSAETLLDFDLSVVALEEDGQLHPKFVSSGLEPDEFDAMSIDEGIAGKTYRTGESYLIEDITEWEEANPQGSWISAISLPIGEFGNFQAVSKEADAFNEQDLQLAELLITHASHHLDRVANKEELEQQNDRLEEFASVVSHDLRNPLSVATGRLELAKDECDSEHLDGIARAHDRMERLIDDLLTLARTGNRVSNIEPVDLATLTANCWENVSTSEATLNTEINRQIQADQSRLKQLLENLMRNAVEHGGDNVTITVGEVDGGFYVEDNGPGIPDEEQEVVFEMGYSTTEGGTGFGLNIVKQIAQAHGWDIHVIDGSTGGARFEITGVEFAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYB8</accession>
    <name>V6DYB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase ISH11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">C449_04902</name>
        <name evidence="1" type="ORF">BN903_54</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">AJ67</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CBVY010000013">
        <property type="protein sequence ID" value="CDK40368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CDK40368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="45" mass="4999" checksum="66D6B189C6939D70" modified="2014-02-19" version="1">MKDCGLGRTHAEAAFMHERRCSLRCGFVSSSQSPTTNEETIREAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-02-19" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>V6DYB9</accession>
    <name>V6DYB9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-dehydroquinate synthase</fullName>
            <shortName evidence="3">DHQ synthase</shortName>
            <ecNumber evidence="3">1.4.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-dehydroquinate synthase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">aroB'</name>
        <name evidence="4" type="ORF">BN903_5</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Halorubrum sp. AJ67</name>
        <dbReference type="NCBI Taxonomy" id="1173487"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Haloferacales</taxon>
            <taxon>Halorubraceae</taxon>
            <taxon>Halorubrum</taxon>
            <taxon>unclassified Halorubrum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Burguener G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2013-12" db="EMBL/GenBank/DDBJ databases">
            <title>Draft Genome Sequence of the poli-extremophilic Halorubrum sp. AJ67, isolated from hyperarsenic lakes, in the Argentinean Puna.</title>
            <authorList>
                <person name="Maldonado M.J."/>
                <person name="Turjanski A."/>
                <person name="Farias M.E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">AJ67</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) = 3-dehydroquinate + H(+) + NADH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:25956"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58859"/>
            <dbReference type="EC" id="1.4.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal-type DHQ synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.24" evidence="3"/>
    <dbReference type="EMBL" id="CBVY010000021">
        <property type="protein sequence ID" value="CDK40876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_048078250.1">
        <property type="nucleotide sequence ID" value="NZ_CBVY010000021.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29853at2157"/>
    <dbReference type="Proteomes" id="UP000018894">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102042">
        <property type="term" value="F:dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01244">
        <property type="entry name" value="Arch_DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002812">
        <property type="entry name" value="DHQ_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563">
        <property type="entry name" value="PTHR33563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01959">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006655">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDK40876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000018894"/>
        </source>
    </evidence>
    <sequence length="390" mass="42126" checksum="782317B443D92982" modified="2014-02-19" version="1">MTRTVWVKADGDVGDWEARKRRVTAAIEAGADWVLVDEGDVGRVRELGDVNVAAFRSDADVIDDAESDAEADAYFVGKGGEGDGTIAMPDDLSGSADLTTLRRRDDRAQGAYVRVLGTEYEAFAEAAADDAEFTVIVGEDWSIIPLENLIARVGEETHLVAGATTAAEARTAFETLEIGADGVLLDADDPDEIRGAVEARDAADRETLDLRYAEVTAIEQTGMADRVCIDTGSLMDDTEGMLVGSMSRGLFFVHAETAESPYVASRPFRVNAGAVHAYVRNAEGGTNYLAELSSGDEVQLVDTDGNTREAVVGRVKIEKRPMFRIQAEIETEEGTDRIETLIQNAETVKIATSEGRKAVTDVEEGDEALVYYEDVARHFGEAVEESIIEK</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>